Spica_1457 9a42412d815d64154876b2723eb1fc70 541 Pfam PF14052 Capsule assembly protein Wzi 193 448 2.5E-18 T 13-10-2018 IPR026950 Capsule assembly protein Wzi Spica_1457 9a42412d815d64154876b2723eb1fc70 541 Gene3D G3DSA:2.40.160.130 152 505 3.2E-22 T 13-10-2018 IPR038636 Capsule assembly protein Wzi superfamily Spica_2805 8dc542736917fc59938d989e19c8521a 140 Gene3D G3DSA:3.40.50.1010 3 137 3.1E-12 T 13-10-2018 Spica_2805 8dc542736917fc59938d989e19c8521a 140 SUPERFAMILY SSF88723 6 126 1.09E-21 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2805 8dc542736917fc59938d989e19c8521a 140 Pfam PF01850 PIN domain 6 123 1.6E-15 T 13-10-2018 IPR002716 PIN domain Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 157 171 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 84 98 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 57 78 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 175 194 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 100 113 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 213 232 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 132 148 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 41 57 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 259 278 3.1E-47 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 PIRSF PIRSF019574 1 354 4.8E-100 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 Pfam PF13416 Bacterial extracellular solute-binding protein 51 306 1.6E-29 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 Gene3D G3DSA:3.40.190.10 39 318 2.8E-115 T 13-10-2018 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 SUPERFAMILY SSF53850 36 352 4.4E-73 T 13-10-2018 Spica_2143 9341a3260abb0590cd2026a8b9ed112d 354 Gene3D G3DSA:3.40.190.10 142 347 2.8E-115 T 13-10-2018 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 Pfam PF01312 FlhB HrpN YscU SpaS Family 34 374 5.8E-122 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 33 380 3.2E-124 T 13-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 Gene3D G3DSA:3.40.1690.10 245 386 9.6E-56 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 329 350 2.8E-40 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 235 253 2.8E-40 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 299 314 2.8E-40 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 36 58 2.8E-40 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 255 272 2.8E-40 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_1526 ee1a4abf27cf72055d791f29d7eb2bd0 386 SUPERFAMILY SSF160544 272 378 2.49E-40 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Spica_1160 fcd56e19b71596276abcfe4904a087ed 195 SUPERFAMILY SSF141571 48 191 1.57E-25 T 13-10-2018 Spica_1160 fcd56e19b71596276abcfe4904a087ed 195 Pfam PF13599 Pentapeptide repeats (9 copies) 114 186 6.8E-13 T 13-10-2018 IPR001646 Pentapeptide repeat Spica_1160 fcd56e19b71596276abcfe4904a087ed 195 Gene3D G3DSA:2.160.20.100 15 195 5.5E-24 T 13-10-2018 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 264 272 - T 13-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 SUPERFAMILY SSF53795 240 605 2.11E-153 T 13-10-2018 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 240 604 4.1E-169 T 13-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Gene3D G3DSA:3.90.228.20 240 603 1.7E-265 T 13-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Gene3D G3DSA:3.40.449.10 13 239 1.7E-265 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 PIRSF PIRSF001348 1 606 4.5E-284 T 13-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Gene3D G3DSA:2.170.8.10 49 398 1.7E-265 T 13-10-2018 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 SUPERFAMILY SSF68923 6 239 8.37E-99 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 13 236 2.8E-102 T 13-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Spica_2387 e1946a44cf9793eebb3a382515034c89 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 2 605 49.232 T 13-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 Spica_0326 855d7bab44276e6d259f421958a83a32 208 Gene3D G3DSA:3.40.50.360 1 208 1.8E-43 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0326 855d7bab44276e6d259f421958a83a32 208 SUPERFAMILY SSF52218 1 203 3.81E-37 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0326 855d7bab44276e6d259f421958a83a32 208 Pfam PF02525 Flavodoxin-like fold 1 192 6.4E-30 T 13-10-2018 IPR003680 Flavodoxin-like fold Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 Pfam PF00672 HAMP domain 233 281 9.8E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 333 507 1.8E-37 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 SMART SM00304 232 285 4.7E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 Gene3D G3DSA:3.30.70.1230 323 525 1.7E-64 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 SUPERFAMILY SSF55073 330 513 1.73E-56 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 SUPERFAMILY SSF158472 233 282 9.55E-8 T 13-10-2018 Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 SMART SM00044 299 506 2.0E-31 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1000 96ef63172b50d7c41716d21addf1bb34 589 Gene3D G3DSA:1.20.1480.50 192 290 2.0E-10 T 13-10-2018 Spica_0419 f30a4c50af03b1664103305666d3d222 678 SUPERFAMILY SSF81271 374 444 1.2E-17 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Spica_0419 f30a4c50af03b1664103305666d3d222 678 SUPERFAMILY SSF109604 13 191 1.08E-67 T 13-10-2018 Spica_0419 f30a4c50af03b1664103305666d3d222 678 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 491 2.0E-193 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 Spica_0419 f30a4c50af03b1664103305666d3d222 678 Gene3D G3DSA:3.30.460.10 193 325 3.7E-47 T 13-10-2018 Spica_0419 f30a4c50af03b1664103305666d3d222 678 Pfam PF13291 ACT domain 605 674 2.2E-6 T 13-10-2018 IPR002912 ACT domain Spica_0419 f30a4c50af03b1664103305666d3d222 678 Gene3D G3DSA:3.10.20.30 378 453 4.1E-30 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_0419 f30a4c50af03b1664103305666d3d222 678 Pfam PF13328 HD domain 26 175 2.3E-51 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0419 f30a4c50af03b1664103305666d3d222 678 SUPERFAMILY SSF81301 181 389 8.99E-57 T 13-10-2018 Spica_0419 f30a4c50af03b1664103305666d3d222 678 Pfam PF02824 TGS domain 385 444 4.0E-18 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Spica_0419 f30a4c50af03b1664103305666d3d222 678 SMART SM00954 235 345 1.2E-61 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Spica_0419 f30a4c50af03b1664103305666d3d222 678 Pfam PF04607 Region found in RelA / SpoT proteins 236 344 7.7E-38 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Spica_0419 f30a4c50af03b1664103305666d3d222 678 Gene3D G3DSA:1.10.3210.10 2 191 5.0E-72 T 13-10-2018 Spica_0419 f30a4c50af03b1664103305666d3d222 678 SMART SM00471 41 153 5.3E-10 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 Pfam PF00005 ABC transporter 53 226 8.2E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 ProSitePatterns PS00211 ABC transporters family signature. 199 213 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 Gene3D G3DSA:3.40.50.300 388 626 4.1E-59 T 13-10-2018 Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 Pfam PF00005 ABC transporter 411 561 2.7E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 Gene3D G3DSA:3.40.50.300 30 295 4.3E-60 T 13-10-2018 Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 Pfam PF02361 Cobalt transport protein 736 951 9.9E-21 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 SUPERFAMILY SSF52540 411 613 7.92E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 SMART SM00382 62 274 9.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 SMART SM00382 420 608 3.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 SUPERFAMILY SSF52540 48 292 4.86E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0697 4f541ea09d472eed164b74dd50d4dd12 957 ProSitePatterns PS00211 ABC transporters family signature. 533 547 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1299 47296a81110c710c1911a4df6772757f 491 Gene3D G3DSA:3.90.1580.10 410 490 5.4E-9 T 13-10-2018 Spica_1299 47296a81110c710c1911a4df6772757f 491 Gene3D G3DSA:3.90.1580.10 293 409 2.1E-9 T 13-10-2018 Spica_1299 47296a81110c710c1911a4df6772757f 491 Pfam PF08308 PEGA domain 58 109 2.8E-10 T 13-10-2018 IPR013229 PEGA Spica_1299 47296a81110c710c1911a4df6772757f 491 Pfam PF03781 Sulfatase-modifying factor enzyme 1 411 483 2.4E-8 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Spica_1299 47296a81110c710c1911a4df6772757f 491 Pfam PF03781 Sulfatase-modifying factor enzyme 1 302 405 4.4E-10 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Spica_1299 47296a81110c710c1911a4df6772757f 491 SUPERFAMILY SSF56436 302 483 3.06E-29 T 13-10-2018 IPR016187 C-type lectin fold Spica_2509 4826f4e1ed4460e21bdbe3042a5b69be 177 SUPERFAMILY SSF55469 1 172 1.57E-54 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_2509 4826f4e1ed4460e21bdbe3042a5b69be 177 Pfam PF00881 Nitroreductase family 7 146 4.1E-25 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Spica_2509 4826f4e1ed4460e21bdbe3042a5b69be 177 Gene3D G3DSA:3.40.109.10 3 175 4.3E-55 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 Gene3D G3DSA:1.25.40.10 239 403 2.3E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 Gene3D G3DSA:1.25.40.10 23 238 1.1E-35 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 27 60 0.014 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 324 357 13.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 61 94 0.0035 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 231 264 270.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 265 298 0.03 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 129 162 99.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 197 230 68.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SMART SM00028 163 196 0.21 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 Pfam PF13432 Tetratricopeptide repeat 237 298 3.0E-9 T 13-10-2018 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 Pfam PF13432 Tetratricopeptide repeat 134 192 4.4E-6 T 13-10-2018 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SUPERFAMILY SSF48452 26 262 2.94E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 SUPERFAMILY SSF48452 236 359 7.02E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1231 222010a4e78ccf4a3a77ee2396d3bac2 659 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 44 119 2.5E-7 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Gene3D G3DSA:3.10.20.310 30 103 1.3E-6 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Gene3D G3DSA:3.10.20.310 356 431 1.4E-21 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF07244 Surface antigen variable number repeat 356 428 3.5E-13 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF07244 Surface antigen variable number repeat 187 271 1.7E-14 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF07244 Surface antigen variable number repeat 274 347 2.2E-12 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF07244 Surface antigen variable number repeat 104 181 2.4E-14 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF07244 Surface antigen variable number repeat 31 103 2.2E-4 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Gene3D G3DSA:3.10.20.310 185 271 4.0E-18 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Gene3D G3DSA:3.10.20.310 104 183 1.2E-16 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Gene3D G3DSA:3.10.20.310 272 354 9.3E-17 T 13-10-2018 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 PIRSF PIRSF006076 1 820 2.6E-146 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 Pfam PF01103 Surface antigen 460 801 1.6E-34 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Spica_1347 8d9af4907c909b000d7a6bd7d568246d 826 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 30 804 1.9E-150 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 105 4.7E-7 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Gene3D G3DSA:3.30.420.130 1 113 3.0E-10 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Gene3D G3DSA:3.30.70.20 215 262 4.7E-10 T 13-10-2018 Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 SUPERFAMILY SSF52540 154 419 1.33E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Gene3D G3DSA:3.40.50.300 153 212 7.1E-10 T 13-10-2018 Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 SUPERFAMILY SSF54862 209 272 6.7E-16 T 13-10-2018 Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Gene3D G3DSA:3.40.50.300 263 436 3.7E-18 T 13-10-2018 Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 SUPERFAMILY SSF53146 1 112 1.7E-13 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 249 260 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0706 b957f2d9b9b799a5de10e254b5503b50 438 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 154 412 4.9E-22 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spica_1788 23d11985f5e9d24f6017775a4c79e3b9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 5.2E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_1788 23d11985f5e9d24f6017775a4c79e3b9 111 SUPERFAMILY SSF143011 29 91 2.94E-7 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1788 23d11985f5e9d24f6017775a4c79e3b9 111 Gene3D G3DSA:3.30.2310.20 1 101 2.1E-20 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1766 23d11985f5e9d24f6017775a4c79e3b9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 5.2E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_1766 23d11985f5e9d24f6017775a4c79e3b9 111 SUPERFAMILY SSF143011 29 91 2.94E-7 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1766 23d11985f5e9d24f6017775a4c79e3b9 111 Gene3D G3DSA:3.30.2310.20 1 101 2.1E-20 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1746 23d11985f5e9d24f6017775a4c79e3b9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 5.2E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_1746 23d11985f5e9d24f6017775a4c79e3b9 111 SUPERFAMILY SSF143011 29 91 2.94E-7 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1746 23d11985f5e9d24f6017775a4c79e3b9 111 Gene3D G3DSA:3.30.2310.20 1 101 2.1E-20 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1755 23d11985f5e9d24f6017775a4c79e3b9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 96 5.2E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_1755 23d11985f5e9d24f6017775a4c79e3b9 111 SUPERFAMILY SSF143011 29 91 2.94E-7 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1755 23d11985f5e9d24f6017775a4c79e3b9 111 Gene3D G3DSA:3.30.2310.20 1 101 2.1E-20 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 SMART SM00387 509 650 5.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 568 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 594 604 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 647 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 628 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 Gene3D G3DSA:1.20.120.160 351 454 2.8E-7 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 SUPERFAMILY SSF55874 494 647 4.71E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 Gene3D G3DSA:3.30.450.20 188 336 3.1E-5 T 13-10-2018 Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 512 648 2.4E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 Gene3D G3DSA:3.30.565.10 466 648 2.8E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2534 9a231667e02c58023eeca2c5776d2e62 657 SUPERFAMILY SSF47226 352 441 2.49E-8 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 SUPERFAMILY SSF74650 121 230 8.47E-13 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 SUPERFAMILY SSF51011 602 685 2.16E-19 T 13-10-2018 Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 Gene3D G3DSA:2.60.40.1760 4 233 2.4E-14 T 13-10-2018 Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 Gene3D G3DSA:2.60.40.1180 633 686 8.4E-7 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 Pfam PF01055 Glycosyl hydrolases family 31 238 688 4.6E-71 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 SUPERFAMILY SSF51445 248 600 9.59E-53 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2068 8f94f78718b3bf0f57e915621acd55cd 723 Gene3D G3DSA:3.20.20.80 245 632 6.4E-90 T 13-10-2018 Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 Gene3D G3DSA:1.10.8.630 2 112 4.3E-25 T 13-10-2018 Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 Pfam PF00271 Helicase conserved C-terminal domain 436 517 3.4E-7 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 Hamap MF_00983 Probable primosomal protein N' [priA]. 5 658 23.871 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 SMART SM00490 421 518 2.7E-8 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 TIGRFAM TIGR00595 priA: primosomal protein N' 152 656 4.7E-189 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 SUPERFAMILY SSF52540 145 528 2.62E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 Gene3D G3DSA:3.40.50.300 113 310 8.6E-63 T 13-10-2018 Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 SMART SM00487 122 323 1.2E-21 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1554 f994de396026a0b1c2c4c5073746fc22 659 Pfam PF00270 DEAD/DEAH box helicase 130 292 2.0E-14 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 Pfam PF00293 NUDIX domain 56 165 1.3E-14 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 PRINTS PR00502 NUDIX hydrolase family signature 77 91 1.6E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 PRINTS PR00502 NUDIX hydrolase family signature 91 106 1.6E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 SUPERFAMILY SSF55811 8 182 7.58E-38 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 ProSitePatterns PS00893 Nudix box signature. 82 103 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spica_0436 05a768dd2fbdeaebfc1f2cdffecb952e 186 Gene3D G3DSA:3.90.79.10 5 182 1.8E-42 T 13-10-2018 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 211 7.6E-88 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 SUPERFAMILY SSF54821 110 207 2.09E-33 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 SUPERFAMILY SSF54814 2 108 7.19E-33 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 Gene3D G3DSA:3.30.1140.32 110 210 7.6E-37 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 SMART SM00322 62 127 4.4E-7 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 Gene3D G3DSA:3.30.300.20 17 109 1.4E-27 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 Pfam PF00189 Ribosomal protein S3, C-terminal domain 122 205 2.5E-34 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 209 36.472 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 Pfam PF07650 KH domain 49 112 1.4E-17 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0391 d83baacf0c373d0a78b61da09ec44e12 234 ProSitePatterns PS00548 Ribosomal protein S3 signature. 166 200 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Gene3D G3DSA:3.40.50.300 436 718 7.3E-102 T 13-10-2018 Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 SUPERFAMILY SSF46785 733 795 1.17E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Pfam PF01580 FtsK/SpoIIIE family 581 631 2.1E-11 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Pfam PF01580 FtsK/SpoIIIE family 452 577 2.2E-44 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Pfam PF09397 Ftsk gamma domain 735 794 3.5E-29 T 13-10-2018 IPR018541 FtsK gamma domain Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 SUPERFAMILY SSF52540 413 705 2.32E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Gene3D G3DSA:3.30.980.40 331 435 1.1E-32 T 13-10-2018 Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 SMART SM00843 733 797 3.4E-34 T 13-10-2018 IPR018541 FtsK gamma domain Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 SMART SM00382 475 654 7.5E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0361 68435482e27ea7e255bbb5aee6dd8dc1 797 Gene3D G3DSA:1.10.10.10 732 794 4.2E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 Gene3D G3DSA:2.40.50.100 2 127 2.5E-48 T 13-10-2018 Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 Pfam PF01597 Glycine cleavage H-protein 8 125 2.3E-42 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 36.159 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 SUPERFAMILY SSF51230 6 124 3.59E-42 T 13-10-2018 IPR011053 Single hybrid motif Spica_2358 05dad96d8bb58b25581e2066a23805fe 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 126 1.5E-43 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 Gene3D G3DSA:3.40.50.2300 5 128 2.0E-25 T 13-10-2018 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 SUPERFAMILY SSF52172 4 161 2.56E-29 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 SUPERFAMILY SSF81606 180 382 7.98E-10 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 192 383 2.7E-25 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 SMART SM00331 163 383 4.3E-17 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 Gene3D G3DSA:3.60.40.10 131 383 1.2E-45 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 Pfam PF00072 Response regulator receiver domain 6 121 9.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0696 1bd0cab8e1e4e6dae5dc8b6d3bcc5dd3 384 SMART SM00448 4 121 7.8E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 SUPERFAMILY SSF51182 100 197 1.64E-26 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 SUPERFAMILY SSF47413 5 72 3.1E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 Pfam PF01381 Helix-turn-helix 11 62 1.3E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 SMART SM00530 10 64 8.9E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 Pfam PF07883 Cupin domain 129 196 2.2E-14 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 Gene3D G3DSA:1.10.260.40 5 72 6.4E-10 T 13-10-2018 Spica_0586 9ad26dc4a5d57f239beba570eb7555f4 201 Gene3D G3DSA:2.60.120.10 89 198 2.9E-28 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0189 595a0259a35845d0d2b306ba50812980 407 Gene3D G3DSA:1.10.357.10 221 390 2.5E-19 T 13-10-2018 Spica_0189 595a0259a35845d0d2b306ba50812980 407 SUPERFAMILY SSF46689 224 297 3.06E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0189 595a0259a35845d0d2b306ba50812980 407 Gene3D G3DSA:1.10.357.10 1 160 4.9E-15 T 13-10-2018 Spica_0189 595a0259a35845d0d2b306ba50812980 407 SUPERFAMILY SSF46689 2 64 9.48E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0189 595a0259a35845d0d2b306ba50812980 407 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 248 271 1.1E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0189 595a0259a35845d0d2b306ba50812980 407 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 227 240 1.1E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0189 595a0259a35845d0d2b306ba50812980 407 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 52 8.7E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0189 595a0259a35845d0d2b306ba50812980 407 Pfam PF00440 Bacterial regulatory proteins, tetR family 227 272 4.3E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2393 bd19b43ea96d5f35e16266d847039dad 331 SUPERFAMILY SSF56935 23 289 1.79E-10 T 13-10-2018 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 Gene3D G3DSA:1.20.120.140 8 291 2.1E-84 T 13-10-2018 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 SMART SM00382 91 250 4.0E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1236 07d99601070da29bbf0f0c50132a247a 296 Pfam PF00448 SRP54-type protein, GTPase domain 93 293 5.0E-68 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 SUPERFAMILY SSF47364 3 76 9.55E-7 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 Gene3D G3DSA:3.40.50.300 88 282 2.1E-84 T 13-10-2018 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 20 291 5.8E-88 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Spica_1236 07d99601070da29bbf0f0c50132a247a 296 SUPERFAMILY SSF52540 93 294 4.84E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1236 07d99601070da29bbf0f0c50132a247a 296 SMART SM00962 92 294 7.9E-92 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.9E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.9E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.9E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.9E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.9E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.3E-30 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 9.1E-213 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 58.735 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Gene3D G3DSA:2.40.30.10 208 336 2.6E-51 T 13-10-2018 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 6.3E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 2.7E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 SUPERFAMILY SSF50465 304 396 2.13E-34 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Gene3D G3DSA:3.40.50.300 1 205 5.0E-68 T 13-10-2018 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 SUPERFAMILY SSF50447 207 303 4.57E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 4.7E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 SUPERFAMILY SSF52540 9 228 1.83E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0383 8078a9c0f76a6032635a19aff6df87cc 396 Gene3D G3DSA:2.40.30.10 340 395 4.2E-25 T 13-10-2018 Spica_0136 cb1d8620a437011ff262ac6ae062ce1c 221 Gene3D G3DSA:2.60.120.10 10 134 4.7E-30 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0136 cb1d8620a437011ff262ac6ae062ce1c 221 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 67 84 - T 13-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0136 cb1d8620a437011ff262ac6ae062ce1c 221 Pfam PF00027 Cyclic nucleotide-binding domain 20 104 1.5E-19 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0136 cb1d8620a437011ff262ac6ae062ce1c 221 SMART SM00100 1 117 1.2E-9 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0136 cb1d8620a437011ff262ac6ae062ce1c 221 SUPERFAMILY SSF51206 13 129 2.09E-26 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Gene3D G3DSA:1.10.720.10 194 242 4.6E-12 T 13-10-2018 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Gene3D G3DSA:2.40.50.140 243 319 5.8E-32 T 13-10-2018 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SUPERFAMILY SSF52540 287 564 3.46E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SMART SM00959 199 243 1.0E-11 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SMART SM00357 248 314 6.7E-16 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 352 556 1.3E-20 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Pfam PF07498 Rho termination factor, N-terminal domain 199 243 2.3E-12 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SMART SM00382 363 548 9.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1604 83c98a7743c9b9572c1106a26158e971 617 TIGRFAM TIGR00767 rho: transcription termination factor Rho 196 610 5.8E-219 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SUPERFAMILY SSF68912 196 243 1.77E-6 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Hamap MF_01884 Transcription termination factor Rho [rho]. 195 613 225.801 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 SUPERFAMILY SSF50249 245 320 8.57E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Gene3D G3DSA:3.40.50.300 326 610 3.3E-127 T 13-10-2018 Spica_1604 83c98a7743c9b9572c1106a26158e971 617 Pfam PF07497 Rho termination factor, RNA-binding domain 249 320 6.4E-29 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 SUPERFAMILY SSF56059 106 309 4.24E-34 T 13-10-2018 Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 Gene3D G3DSA:3.30.470.20 190 399 1.1E-37 T 13-10-2018 Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 Gene3D G3DSA:3.40.50.20 1 120 5.9E-34 T 13-10-2018 Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 Pfam PF13535 ATP-grasp domain 143 283 3.3E-15 T 13-10-2018 Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 SUPERFAMILY SSF52440 3 67 1.04E-8 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_1633 abb4cc4f83a610002ab92aa148ec1d72 535 Gene3D G3DSA:3.30.1490.20 122 189 2.7E-8 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 SUPERFAMILY SSF53223 1 121 3.36E-39 T 13-10-2018 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 Gene3D G3DSA:3.40.50.720 6 266 1.0E-116 T 13-10-2018 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 SUPERFAMILY SSF51735 122 289 4.5E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 288 7.8E-70 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 267 275 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 246 262 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 263 281 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 1.0E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 290 40.173 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 5.7E-41 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 Gene3D G3DSA:3.40.50.10860 8 283 1.0E-116 T 13-10-2018 Spica_1133 2eda31640d7e1266fc3a62b53c009d5e 293 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PIRSF PIRSF002869 22 539 6.2E-138 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 Pfam PF03023 MviN-like protein 53 478 4.6E-108 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 280 306 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 151 175 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 175 196 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 76 92 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 378 397 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 430 447 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 PRINTS PR01806 Virulence factor MviN signature 57 76 4.5E-53 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 27 491 17.172 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2511 8940a06d232b4cb9d34e916421d6bd62 541 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 26 529 4.9E-121 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Gene3D G3DSA:2.40.50.140 607 767 1.2E-35 T 13-10-2018 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 SUPERFAMILY SSF57770 138 172 3.27E-11 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Pfam PF09334 tRNA synthetases class I (M) 5 403 6.7E-158 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 554 39.077 T 13-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 SUPERFAMILY SSF50249 610 724 4.16E-31 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 544 2.1E-179 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Gene3D G3DSA:1.10.730.10 386 555 2.2E-39 T 13-10-2018 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Gene3D G3DSA:2.20.28.20 138 172 3.0E-169 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 SUPERFAMILY SSF52374 2 389 9.07E-93 T 13-10-2018 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Gene3D G3DSA:3.40.50.620 5 385 3.0E-169 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 390 401 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 86 97 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 295 310 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 38 52 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 6.3E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 SUPERFAMILY SSF47323 391 543 2.99E-34 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1283 ae9b8e26fa925bbc09384d89130decee 767 Pfam PF01588 Putative tRNA binding domain 614 698 3.9E-28 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Spica_2402 e09b80ec84674964d164bb1953eda41e 417 SMART SM00854 72 315 1.1E-87 T 13-10-2018 IPR019079 Capsule synthesis protein, CapA Spica_2402 e09b80ec84674964d164bb1953eda41e 417 SUPERFAMILY SSF56300 71 316 1.36E-39 T 13-10-2018 Spica_2402 e09b80ec84674964d164bb1953eda41e 417 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 72 314 3.0E-76 T 13-10-2018 IPR019079 Capsule synthesis protein, CapA Spica_2116 c2411e318955a119023ba84efc39e77e 983 SUPERFAMILY SSF48452 32 199 2.8E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SUPERFAMILY SSF48452 552 685 4.17E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 101 223 6.2E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 24 100 7.6E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SUPERFAMILY SSF48452 663 797 7.91E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Pfam PF13432 Tetratricopeptide repeat 36 91 1.3E-6 T 13-10-2018 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Pfam PF13432 Tetratricopeptide repeat 671 730 1.0E-5 T 13-10-2018 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Pfam PF13432 Tetratricopeptide repeat 562 624 3.0E-6 T 13-10-2018 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SUPERFAMILY SSF48452 286 478 3.22E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 441 624 6.4E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 865 983 1.0E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 224 428 2.1E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 364 397 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 29 62 190.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 666 699 18.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 555 588 30.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 438 471 180.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 892 925 24.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 292 325 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 SMART SM00028 66 98 93.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2116 c2411e318955a119023ba84efc39e77e 983 Gene3D G3DSA:1.25.40.10 666 845 1.9E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 Gene3D G3DSA:3.30.300.20 1 105 6.5E-28 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 13-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 SUPERFAMILY SSF89919 1 113 1.7E-24 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 4 110 21.304 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 94 1.0E-20 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 Pfam PF02033 Ribosome-binding factor A 5 107 4.4E-24 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Spica_1355 39d6b1dfbd1749bca62e639729b7877f 119 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 3.7E-27 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Spica_1886 cc59d66419b67025ed32d75267933234 144 SMART SM00344 3 108 2.0E-15 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Spica_1886 cc59d66419b67025ed32d75267933234 144 Pfam PF01037 Lrp/AsnC ligand binding domain 76 138 1.5E-10 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Spica_1886 cc59d66419b67025ed32d75267933234 144 SUPERFAMILY SSF54909 64 140 7.78E-12 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Spica_1886 cc59d66419b67025ed32d75267933234 144 SUPERFAMILY SSF46785 2 51 3.27E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1886 cc59d66419b67025ed32d75267933234 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 3.1E-5 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Spica_1886 cc59d66419b67025ed32d75267933234 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.1E-5 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Spica_1886 cc59d66419b67025ed32d75267933234 144 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 46 1.6E-9 T 13-10-2018 Spica_1886 cc59d66419b67025ed32d75267933234 144 Gene3D G3DSA:3.30.70.920 53 143 8.8E-14 T 13-10-2018 Spica_1886 cc59d66419b67025ed32d75267933234 144 Gene3D G3DSA:1.10.10.10 3 49 3.7E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2269 832cf590758e4ad891c7c57462570071 111 Gene3D G3DSA:1.10.260.40 1 72 5.7E-18 T 13-10-2018 Spica_2269 832cf590758e4ad891c7c57462570071 111 Pfam PF01381 Helix-turn-helix 14 65 4.9E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2269 832cf590758e4ad891c7c57462570071 111 SMART SM00530 13 68 1.4E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2269 832cf590758e4ad891c7c57462570071 111 SUPERFAMILY SSF47413 2 70 3.1E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0295 9dfacf778e42450ecadf173d41618ceb 211 Pfam PF00072 Response regulator receiver domain 12 124 1.0E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0295 9dfacf778e42450ecadf173d41618ceb 211 SUPERFAMILY SSF52172 6 145 2.56E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0295 9dfacf778e42450ecadf173d41618ceb 211 Gene3D G3DSA:3.40.50.12740 12 171 7.7E-41 T 13-10-2018 Spica_0295 9dfacf778e42450ecadf173d41618ceb 211 SMART SM00448 10 123 2.9E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.5E-19 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 426 4.1E-178 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 SUPERFAMILY SSF52540 42 354 2.12E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Pfam PF00448 SRP54-type protein, GTPase domain 102 296 1.7E-74 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 SMART SM00382 100 247 1.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0490 ace489999666bb86d4655d0f9f903c59 453 SMART SM00963 1 86 5.7E-29 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Pfam PF02978 Signal peptide binding domain 328 424 9.2E-32 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Gene3D G3DSA:1.10.260.30 309 447 1.2E-38 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Gene3D G3DSA:3.40.50.300 90 285 2.3E-122 T 13-10-2018 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 SMART SM00962 101 296 1.3E-106 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 451 32.867 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 SUPERFAMILY SSF47446 327 427 1.29E-32 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Spica_0490 ace489999666bb86d4655d0f9f903c59 453 Gene3D G3DSA:1.20.120.140 5 306 2.3E-122 T 13-10-2018 Spica_1638 29a2dfc929c97947a8ebed99838c155e 410 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 396 26.219 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Spica_1638 29a2dfc929c97947a8ebed99838c155e 410 Pfam PF13742 OB-fold nucleic acid binding domain 7 99 1.3E-30 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 Spica_1638 29a2dfc929c97947a8ebed99838c155e 410 Pfam PF02601 Exonuclease VII, large subunit 333 393 4.7E-7 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Spica_1638 29a2dfc929c97947a8ebed99838c155e 410 Pfam PF02601 Exonuclease VII, large subunit 123 338 2.5E-69 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Spica_1638 29a2dfc929c97947a8ebed99838c155e 410 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 395 8.7E-133 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Spica_2427 da9c0af87b280a3b20537fad30214327 379 SUPERFAMILY SSF53822 31 375 2.89E-69 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2427 da9c0af87b280a3b20537fad30214327 379 Gene3D G3DSA:3.40.50.2300 149 284 7.7E-71 T 13-10-2018 Spica_2427 da9c0af87b280a3b20537fad30214327 379 Gene3D G3DSA:3.40.50.2300 34 353 7.7E-71 T 13-10-2018 Spica_2427 da9c0af87b280a3b20537fad30214327 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 1.2E-10 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_2427 da9c0af87b280a3b20537fad30214327 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 266 284 1.2E-10 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_2427 da9c0af87b280a3b20537fad30214327 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 73 91 1.2E-10 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_2427 da9c0af87b280a3b20537fad30214327 379 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 1.2E-10 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_2427 da9c0af87b280a3b20537fad30214327 379 Pfam PF13458 Periplasmic binding protein 31 349 4.3E-55 T 13-10-2018 IPR028081 Leucine-binding protein domain Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Gene3D G3DSA:1.25.40.10 308 384 1.6E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF07719 Tetratricopeptide repeat 275 301 3.9E-5 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF13432 Tetratricopeptide repeat 141 191 0.0052 T 13-10-2018 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 66 99 0.063 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 32 65 0.61 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 238 271 0.078 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 306 338 9.5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 204 237 0.0051 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 168 201 0.53 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 339 372 230.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 272 305 5.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 134 167 9.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SMART SM00028 100 133 1.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SUPERFAMILY SSF48452 237 360 2.4E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Gene3D G3DSA:1.25.40.10 205 307 6.1E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Gene3D G3DSA:1.25.40.10 132 204 4.5E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF13174 Tetratricopeptide repeat 239 270 0.026 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Gene3D G3DSA:1.25.40.10 17 131 4.3E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 SUPERFAMILY SSF81901 37 272 1.36E-35 T 13-10-2018 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF14559 Tetratricopeptide repeat 318 373 4.8E-10 T 13-10-2018 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF14559 Tetratricopeptide repeat 78 131 2.7E-10 T 13-10-2018 Spica_1434 ca7d73828f02dd4c96879907d98ac201 384 Pfam PF13181 Tetratricopeptide repeat 205 236 0.0019 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1576 b65e3b3e0f9ec7f9367adf85dc91e54b 614 SUPERFAMILY SSF58104 392 608 1.1E-6 T 13-10-2018 Spica_1576 b65e3b3e0f9ec7f9367adf85dc91e54b 614 Pfam PF07695 7TM diverse intracellular signalling 183 374 3.3E-11 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 Spica_1576 b65e3b3e0f9ec7f9367adf85dc91e54b 614 SUPERFAMILY SSF49785 8 153 1.03E-8 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_1576 b65e3b3e0f9ec7f9367adf85dc91e54b 614 Gene3D G3DSA:2.60.120.260 20 174 1.2E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 Pfam PF01894 Uncharacterised protein family UPF0047 15 127 1.2E-43 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 2 128 4.7E-48 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 Gene3D G3DSA:2.60.120.460 1 130 2.5E-54 T 13-10-2018 IPR035917 YjbQ-like superfamily Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 92 110 - T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 SUPERFAMILY SSF111038 3 128 3.4E-48 T 13-10-2018 IPR035917 YjbQ-like superfamily Spica_0720 2367e4c29ac1683eaa0f45b80a1cf88d 130 PIRSF PIRSF004681 1 130 3.2E-41 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_1705 325adb2ab148b66f142f2bd06386182f 92 Pfam PF13616 PPIC-type PPIASE domain 5 90 6.4E-25 T 13-10-2018 Spica_1705 325adb2ab148b66f142f2bd06386182f 92 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 29 49 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 Spica_1705 325adb2ab148b66f142f2bd06386182f 92 Gene3D G3DSA:3.10.50.40 2 91 3.5E-36 T 13-10-2018 Spica_1705 325adb2ab148b66f142f2bd06386182f 92 SUPERFAMILY SSF54534 2 88 4.78E-32 T 13-10-2018 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 192 344 2.7E-32 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 142 6.7E-39 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 SUPERFAMILY SSF53756 3 359 1.77E-94 T 13-10-2018 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 355 4.4E-87 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 359 29.757 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 Gene3D G3DSA:3.40.50.2000 180 343 3.0E-43 T 13-10-2018 Spica_1513 02d4b190f7c88bc6d084444e747ed7b6 363 Gene3D G3DSA:3.40.50.2000 1 179 1.6E-57 T 13-10-2018 Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 SUPERFAMILY SSF102114 71 282 1.05E-28 T 13-10-2018 Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 17 335 1.3E-84 T 13-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 Pfam PF04055 Radical SAM superfamily 84 227 1.7E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 PIRSF PIRSF004869 1 309 1.9E-79 T 13-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 Gene3D G3DSA:3.20.20.70 70 279 4.6E-33 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1186 45c42e3199eed8dc7df080263f8eaa8a 338 Pfam PF13353 4Fe-4S single cluster domain 80 172 1.1E-5 T 13-10-2018 Spica_2341 09a8e22185d409a65cbe60c160f46007 569 SMART SM00283 237 484 1.5E-59 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2341 09a8e22185d409a65cbe60c160f46007 569 SUPERFAMILY SSF58104 257 488 8.89E-54 T 13-10-2018 Spica_2341 09a8e22185d409a65cbe60c160f46007 569 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 138 1.6E-12 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Spica_2341 09a8e22185d409a65cbe60c160f46007 569 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 299 451 1.2E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2341 09a8e22185d409a65cbe60c160f46007 569 Gene3D G3DSA:1.10.287.950 219 486 1.9E-57 T 13-10-2018 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Gene3D G3DSA:3.30.1490.20 44 126 2.3E-24 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Pfam PF13380 CoA binding domain 287 409 1.1E-6 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Gene3D G3DSA:3.40.50.720 264 412 1.6E-17 T 13-10-2018 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 SUPERFAMILY SSF56059 26 246 1.04E-10 T 13-10-2018 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 SUPERFAMILY SSF52210 583 741 3.66E-11 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Gene3D G3DSA:3.40.50.261 418 576 2.2E-41 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Gene3D G3DSA:3.40.50.261 580 746 6.9E-13 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 438 573 8.5E-38 T 13-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 SUPERFAMILY SSF52210 419 573 4.71E-28 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 SUPERFAMILY SSF51735 274 411 2.31E-12 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Gene3D G3DSA:3.30.470.20 23 255 2.3E-24 T 13-10-2018 Spica_0687 4fb9bf1967e833501d0d6f4187be254a 747 Pfam PF13549 ATP-grasp domain 18 256 1.4E-28 T 13-10-2018 Spica_2546 86d419e767a0a1316abdf7b6d70b2fc2 108 Pfam PF13518 Helix-turn-helix domain 22 70 1.8E-9 T 13-10-2018 Spica_2546 86d419e767a0a1316abdf7b6d70b2fc2 108 SUPERFAMILY SSF46689 17 82 1.97E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2022 739e0eea746727806afeffcf9082a97c 496 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 290 487 1.4E-39 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Spica_2022 739e0eea746727806afeffcf9082a97c 496 SUPERFAMILY SSF51445 17 376 2.64E-112 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2022 739e0eea746727806afeffcf9082a97c 496 Pfam PF03662 Glycosyl hydrolase family 79, N-terminal domain 155 284 1.8E-5 T 13-10-2018 IPR005199 Glycoside hydrolase, family 79 GO:0016020|GO:0016798 Reactome: R-HSA-2024096 Spica_2022 739e0eea746727806afeffcf9082a97c 496 Gene3D G3DSA:3.20.20.80 18 377 7.5E-213 T 13-10-2018 Spica_2022 739e0eea746727806afeffcf9082a97c 496 SUPERFAMILY SSF51011 365 493 1.19E-28 T 13-10-2018 Spica_2022 739e0eea746727806afeffcf9082a97c 496 Gene3D G3DSA:2.60.40.1180 6 492 7.5E-213 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2022 739e0eea746727806afeffcf9082a97c 496 SMART SM00813 290 487 7.8E-74 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 SUPERFAMILY SSF46785 13 92 9.92E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 7.0E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 7.0E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 7.0E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 7.0E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 SMART SM00418 14 88 3.8E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 Pfam PF01022 Bacterial regulatory protein, arsR family 22 66 3.6E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2622 97d7dac8dba3e40f0ce76c7d446c3e69 104 Gene3D G3DSA:1.10.10.10 1 101 3.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF55073 960 1127 2.04E-30 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Gene3D G3DSA:3.30.565.10 593 765 7.2E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Pfam PF08447 PAS fold 424 497 6.4E-7 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Gene3D G3DSA:3.30.70.270 950 1132 9.7E-38 T 13-10-2018 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00388 529 594 9.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Pfam PF00512 His Kinase A (phospho-acceptor) domain 530 594 5.3E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 251 369 7.1E-13 T 13-10-2018 IPR000014 PAS domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 399 516 1.6E-11 T 13-10-2018 IPR000014 PAS domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 642 763 1.7E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF55785 245 360 9.77E-18 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF47384 514 595 2.55E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF55785 410 518 2.9E-15 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Pfam PF00990 Diguanylate cyclase, GGDEF domain 957 1125 4.9E-28 T 13-10-2018 IPR000160 GGDEF domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Gene3D G3DSA:3.30.450.20 384 505 2.6E-14 T 13-10-2018 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 956 1127 1.3E-31 T 13-10-2018 IPR000160 GGDEF domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00091 399 465 0.0031 T 13-10-2018 IPR000014 PAS domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00091 249 315 0.6 T 13-10-2018 IPR000014 PAS domain Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Pfam PF08448 PAS fold 258 363 1.6E-19 T 13-10-2018 IPR013656 PAS fold-4 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF52172 800 945 4.97E-5 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Gene3D G3DSA:3.30.450.20 236 375 3.5E-25 T 13-10-2018 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 Gene3D G3DSA:1.10.287.130 506 592 1.1E-23 T 13-10-2018 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SUPERFAMILY SSF55874 583 765 1.7E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00086 319 362 2.7 T 13-10-2018 IPR001610 PAC motif Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00086 471 509 12.0 T 13-10-2018 IPR001610 PAC motif Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00387 641 765 6.7E-39 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 690 704 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 708 718 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 725 743 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 762 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2655 c8c33112718ced4c3eb604d663d850a0 1148 SMART SM00267 944 1129 7.0E-32 T 13-10-2018 IPR000160 GGDEF domain Spica_1987 8bb7608ccab8ab067ad05202758ef3af 503 SUPERFAMILY SSF53067 253 495 5.5E-7 T 13-10-2018 Spica_1987 8bb7608ccab8ab067ad05202758ef3af 503 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 244 2.3E-16 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_1987 8bb7608ccab8ab067ad05202758ef3af 503 Gene3D G3DSA:3.30.420.40 237 503 1.0E-68 T 13-10-2018 Spica_1987 8bb7608ccab8ab067ad05202758ef3af 503 Gene3D G3DSA:3.30.420.40 1 236 1.4E-34 T 13-10-2018 Spica_1987 8bb7608ccab8ab067ad05202758ef3af 503 SUPERFAMILY SSF53067 5 243 2.92E-23 T 13-10-2018 Spica_2808 2abaeb14d6a818b8da042267f499cfda 294 SUPERFAMILY SSF51395 63 292 1.78E-21 T 13-10-2018 Spica_2808 2abaeb14d6a818b8da042267f499cfda 294 Pfam PF01070 FMN-dependent dehydrogenase 170 292 1.5E-21 T 13-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Spica_2808 2abaeb14d6a818b8da042267f499cfda 294 Gene3D G3DSA:3.20.20.70 34 294 9.0E-26 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0727 ed281ade94dd41c252e013b3f10428cd 273 SUPERFAMILY SSF161098 10 268 3.18E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0727 ed281ade94dd41c252e013b3f10428cd 273 Gene3D G3DSA:1.10.3720.10 5 266 3.4E-45 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0727 ed281ade94dd41c252e013b3f10428cd 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 264 1.7E-12 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 1.3E-54 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 TIGRFAM TIGR01393 lepA: elongation factor 4 6 598 0.0 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Pfam PF00679 Elongation factor G C-terminus 403 489 1.1E-21 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Gene3D G3DSA:2.40.30.10 189 288 4.8E-34 T 13-10-2018 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 SUPERFAMILY SSF54980 404 497 2.59E-24 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Gene3D G3DSA:3.30.70.870 289 370 6.8E-36 T 13-10-2018 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 SUPERFAMILY SSF54980 295 373 1.8E-19 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Gene3D G3DSA:3.40.50.300 2 188 3.8E-72 T 13-10-2018 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 286.825 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 PRINTS PR00315 GTP-binding elongation factor signature 52 60 7.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 PRINTS PR00315 GTP-binding elongation factor signature 9 22 7.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 PRINTS PR00315 GTP-binding elongation factor signature 77 87 7.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 PRINTS PR00315 GTP-binding elongation factor signature 129 138 7.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 PRINTS PR00315 GTP-binding elongation factor signature 93 104 7.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 SUPERFAMILY SSF52540 2 203 3.9E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Gene3D G3DSA:3.30.70.2570 483 557 5.6E-32 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Pfam PF06421 GTP-binding protein LepA C-terminus 491 597 1.0E-47 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Gene3D G3DSA:3.30.70.3380 371 482 2.7E-44 T 13-10-2018 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 Pfam PF03144 Elongation factor Tu domain 2 208 278 2.7E-10 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 SUPERFAMILY SSF50447 168 291 8.52E-32 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0806 c2a5d6966db6a3d5594016d966ad4956 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 179 6.6E-20 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 PIRSF PIRSF003107 1 219 9.9E-59 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 214 3.2E-59 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 Gene3D G3DSA:1.20.58.220 3 219 7.8E-67 T 13-10-2018 IPR038078 PhoU-like domain superfamily Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 Pfam PF01895 PhoU domain 18 105 3.8E-21 T 13-10-2018 IPR026022 PhoU domain Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 Pfam PF01895 PhoU domain 121 205 1.3E-14 T 13-10-2018 IPR026022 PhoU domain Spica_0768 4b4d126a3ac698f440c1c3416046f42b 219 SUPERFAMILY SSF109755 5 218 1.15E-58 T 13-10-2018 Spica_0313 8b608f8cef26643c366ff29a01ba3382 313 Gene3D G3DSA:3.40.190.10 112 249 4.4E-106 T 13-10-2018 Spica_0313 8b608f8cef26643c366ff29a01ba3382 313 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 312 7.9E-108 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Spica_0313 8b608f8cef26643c366ff29a01ba3382 313 Pfam PF16868 NMT1-like family 28 311 1.1E-92 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family Spica_0313 8b608f8cef26643c366ff29a01ba3382 313 Gene3D G3DSA:3.40.190.10 28 310 4.4E-106 T 13-10-2018 Spica_0313 8b608f8cef26643c366ff29a01ba3382 313 SUPERFAMILY SSF53850 23 310 1.02E-80 T 13-10-2018 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 SUPERFAMILY SSF55257 14 243 2.16E-30 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Gene3D G3DSA:3.30.1360.10 26 235 2.5E-75 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 27 329 4.1E-111 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 270 329 2.0E-16 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Gene3D G3DSA:1.10.150.20 236 351 2.4E-32 T 13-10-2018 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 SMART SM00662 27 244 3.1E-65 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 260 322 7.3E-27 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Gene3D G3DSA:2.170.120.12 57 187 2.5E-75 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 SUPERFAMILY SSF56553 57 188 1.62E-26 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 75 169 4.3E-14 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 SUPERFAMILY SSF47789 264 333 3.14E-25 T 13-10-2018 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 7 330 34.503 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0410 2049c3ebb6121ab68d81446e5c68ab66 351 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 34 238 4.4E-24 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0734 57cd994d2fa989f39611765068bada4b 455 Gene3D G3DSA:1.20.1480.50 139 231 1.2E-10 T 13-10-2018 Spica_0734 57cd994d2fa989f39611765068bada4b 455 Gene3D G3DSA:1.10.287.130 232 294 4.0E-14 T 13-10-2018 Spica_0734 57cd994d2fa989f39611765068bada4b 455 SMART SM00304 173 225 2.1E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0734 57cd994d2fa989f39611765068bada4b 455 SUPERFAMILY SSF55874 282 453 7.33E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0734 57cd994d2fa989f39611765068bada4b 455 SMART SM00387 340 455 1.5E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0734 57cd994d2fa989f39611765068bada4b 455 Pfam PF00672 HAMP domain 174 220 6.1E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0734 57cd994d2fa989f39611765068bada4b 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 292 7.0E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0734 57cd994d2fa989f39611765068bada4b 455 Gene3D G3DSA:3.30.565.10 310 454 2.6E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0734 57cd994d2fa989f39611765068bada4b 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 452 1.2E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0734 57cd994d2fa989f39611765068bada4b 455 SUPERFAMILY SSF158472 174 222 4.71E-7 T 13-10-2018 Spica_0734 57cd994d2fa989f39611765068bada4b 455 SMART SM00388 226 293 5.8E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0734 57cd994d2fa989f39611765068bada4b 455 SUPERFAMILY SSF47384 209 293 1.59E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0734 57cd994d2fa989f39611765068bada4b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 5.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0734 57cd994d2fa989f39611765068bada4b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 5.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0734 57cd994d2fa989f39611765068bada4b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0734 57cd994d2fa989f39611765068bada4b 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.8E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 Pfam PF00149 Calcineurin-like phosphoesterase 334 531 1.3E-17 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 SUPERFAMILY SSF49785 31 192 1.7E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 230 324 2.7E-12 T 13-10-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 SUPERFAMILY SSF49363 230 325 1.31E-6 T 13-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 SUPERFAMILY SSF56300 330 555 6.65E-38 T 13-10-2018 Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 Gene3D G3DSA:2.60.120.260 82 252 4.7E-13 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0206 696ab8aa739ddf743b572ff89e6a9cbf 631 Gene3D G3DSA:3.60.21.10 328 578 1.5E-44 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_2559 aa08c219937ea547bdc309dc12e88c68 115 Pfam PF13411 MerR HTH family regulatory protein 4 70 1.3E-15 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spica_2559 aa08c219937ea547bdc309dc12e88c68 115 SMART SM00422 4 74 0.009 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Spica_2559 aa08c219937ea547bdc309dc12e88c68 115 SUPERFAMILY SSF46955 4 100 1.83E-14 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Spica_2559 aa08c219937ea547bdc309dc12e88c68 115 Gene3D G3DSA:1.10.1660.10 1 74 1.4E-18 T 13-10-2018 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 Gene3D G3DSA:3.40.640.10 62 298 4.4E-133 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 Pfam PF00155 Aminotransferase class I and II 49 388 3.1E-67 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 397 51.724 T 13-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 SUPERFAMILY SSF53383 4 397 5.32E-115 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 398 2.9E-178 T 13-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Spica_0682 5008ef8ef3c72f39cc913708e89d5618 401 Gene3D G3DSA:3.90.1150.10 48 389 4.4E-133 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SUPERFAMILY SSF52172 508 617 1.32E-22 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SUPERFAMILY SSF55785 121 240 9.6E-13 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SUPERFAMILY SSF47384 252 324 1.39E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 252 1.4E-11 T 13-10-2018 IPR000014 PAS domain Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Pfam PF00989 PAS fold 132 227 8.2E-9 T 13-10-2018 IPR013767 PAS fold GO:0006355 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SMART SM00091 132 200 0.0013 T 13-10-2018 IPR000014 PAS domain Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Gene3D G3DSA:3.30.565.10 327 492 5.3E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SMART SM00448 508 620 5.5E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SMART SM00448 2 114 4.9E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SMART SM00387 367 488 3.5E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Gene3D G3DSA:3.40.50.2300 1 127 1.1E-29 T 13-10-2018 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Gene3D G3DSA:3.30.450.20 128 241 1.3E-15 T 13-10-2018 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SUPERFAMILY SSF55874 316 485 1.7E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Gene3D G3DSA:3.40.50.2300 505 620 2.3E-22 T 13-10-2018 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 3.8E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 431 3.8E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 445 3.8E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 3.8E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Gene3D G3DSA:1.10.287.130 252 325 5.7E-22 T 13-10-2018 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SUPERFAMILY SSF52172 1 137 3.42E-31 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0803 73b4e364ad75c1c27bc2899559432388 620 SMART SM00388 260 326 2.8E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Pfam PF00072 Response regulator receiver domain 510 617 3.7E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Pfam PF00072 Response regulator receiver domain 4 115 3.7E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 325 9.0E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0803 73b4e364ad75c1c27bc2899559432388 620 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 486 3.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0125 50cd5e69dea69975db4b6bdf4692063c 317 Gene3D G3DSA:3.40.50.2300 139 270 2.4E-70 T 13-10-2018 Spica_0125 50cd5e69dea69975db4b6bdf4692063c 317 SUPERFAMILY SSF53822 37 311 1.04E-73 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0125 50cd5e69dea69975db4b6bdf4692063c 317 Pfam PF13407 Periplasmic binding protein domain 43 291 5.2E-55 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0125 50cd5e69dea69975db4b6bdf4692063c 317 Gene3D G3DSA:3.40.50.2300 39 294 2.4E-70 T 13-10-2018 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SUPERFAMILY SSF48452 138 315 8.22E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SUPERFAMILY SSF46557 743 816 1.31E-17 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 Gene3D G3DSA:1.10.287.180 740 813 2.2E-16 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 820 893 6.6E-20 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 743 892 6.9E-45 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 Gene3D G3DSA:3.10.50.30 814 896 4.9E-17 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SUPERFAMILY SSF54534 818 892 2.62E-15 T 13-10-2018 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SMART SM00028 150 183 0.26 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SMART SM00028 278 311 84.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 SMART SM00028 224 257 27.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 Hamap MF_00105 Transcription elongation factor GreA [greA]. 740 893 23.605 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 Pfam PF03449 Transcription elongation factor, N-terminal 743 812 8.5E-18 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Spica_1365 11c1d839176cb56592a53b32aeae93eb 898 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 858 874 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 Gene3D G3DSA:1.10.150.520 16 106 3.5E-40 T 13-10-2018 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 99 205 9.3E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 200 6.6E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 104 207 2.5E-13 T 13-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 SUPERFAMILY SSF56784 1 216 8.01E-43 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 Gene3D G3DSA:3.40.50.1000 3 225 3.5E-40 T 13-10-2018 IPR023214 HAD superfamily Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 204 1.9E-27 T 13-10-2018 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 167 187 3.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 165 3.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0205 71b982d389e4ee7fccc1e714219a72a1 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 118 131 3.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 SUPERFAMILY SSF53383 251 608 1.46E-76 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Gene3D G3DSA:3.40.640.10 261 506 1.1E-96 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 SUPERFAMILY SSF53448 3 269 4.51E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 251 610 124.492 T 13-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Pfam PF00266 Aminotransferase class-V 266 529 1.9E-28 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Pfam PF12804 MobA-like NTP transferase domain 5 109 1.4E-9 T 13-10-2018 IPR025877 MobA-like NTP transferase Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 251 604 1.5E-116 T 13-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Gene3D G3DSA:3.90.550.10 4 236 1.9E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1333 07d624a0e6abac3fbe51c07cdc0f4b58 610 Gene3D G3DSA:3.90.1150.10 252 604 1.1E-96 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 SUPERFAMILY SSF51621 252 550 2.15E-105 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 261 542 2.7E-113 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Gene3D G3DSA:1.10.274.10 24 150 2.7E-69 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Gene3D G3DSA:3.50.30.10 7 235 2.7E-69 T 13-10-2018 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 SUPERFAMILY SSF47831 34 147 7.06E-26 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 155 227 1.9E-19 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Gene3D G3DSA:3.20.20.60 236 572 3.6E-121 T 13-10-2018 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 567 1.1E-190 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 130 2.7E-27 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 SUPERFAMILY SSF52009 130 248 2.35E-28 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 PIRSF PIRSF000732 1 572 1.3E-201 T 13-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 6.4E-26 T 13-10-2018 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 6.4E-26 T 13-10-2018 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 6.4E-26 T 13-10-2018 Spica_2250 2e5c41fe66f4285c8500cce03572b4dd 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 6.4E-26 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Gene3D G3DSA:3.10.450.50 895 931 8.9E-8 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SUPERFAMILY SSF81886 631 921 9.68E-70 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily Spica_1443 0bb914a0386619efded54d3fb29f4692 931 ProSitePatterns PS01312 SecA family signature. 505 520 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Pfam PF01043 SecA preprotein cross-linking domain 253 363 7.1E-35 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SMART SM00958 228 363 7.0E-60 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Gene3D G3DSA:3.40.50.300 422 630 1.9E-88 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SUPERFAMILY SSF52540 4 420 1.41E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SUPERFAMILY SSF81767 269 372 6.28E-37 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SMART SM00957 6 407 4.9E-260 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Gene3D G3DSA:3.90.1440.10 229 373 5.9E-165 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 841 19.635 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Pfam PF07517 SecA DEAD-like domain 7 407 9.1E-123 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Gene3D G3DSA:1.10.3060.10 632 842 1.6E-60 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Pfam PF02810 SEC-C motif 913 931 1.9E-9 T 13-10-2018 IPR004027 SEC-C motif Spica_1443 0bb914a0386619efded54d3fb29f4692 931 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 827 0.0 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 SUPERFAMILY SSF52540 422 629 1.33E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 418 431 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 117 127 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 381 398 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 344 366 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 63 87 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 170 190 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 PRINTS PR00906 SecA protein signature 101 115 2.9E-68 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Gene3D G3DSA:3.40.50.300 24 420 5.9E-165 T 13-10-2018 Spica_1443 0bb914a0386619efded54d3fb29f4692 931 Pfam PF07516 SecA Wing and Scaffold domain 628 835 1.4E-59 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 Gene3D G3DSA:2.30.40.10 387 448 1.2E-13 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 ProSitePatterns PS00482 Dihydroorotase signature 1. 67 75 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 SUPERFAMILY SSF51338 1 448 5.4E-17 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 Pfam PF01979 Amidohydrolase family 60 445 8.5E-28 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 Gene3D G3DSA:3.20.20.140 65 386 3.1E-89 T 13-10-2018 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 SUPERFAMILY SSF51556 65 391 6.08E-79 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 447 5.4E-94 T 13-10-2018 Spica_2551 3ff721fdf5263015bbf5f1cc4b11193b 450 ProSitePatterns PS00483 Dihydroorotase signature 2. 330 341 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0400 ee2023246df4d83195baafe2119f03df 179 SUPERFAMILY SSF56053 83 176 3.74E-32 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.7E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_0400 ee2023246df4d83195baafe2119f03df 179 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.7E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_0400 ee2023246df4d83195baafe2119f03df 179 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.7E-29 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_0400 ee2023246df4d83195baafe2119f03df 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.7E-70 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_0400 ee2023246df4d83195baafe2119f03df 179 PIRSF PIRSF002162 1 177 1.6E-46 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 Pfam PF00347 Ribosomal protein L6 11 82 9.8E-16 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 Pfam PF00347 Ribosomal protein L6 91 164 3.7E-15 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 SUPERFAMILY SSF56053 1 82 6.15E-25 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 Gene3D G3DSA:3.90.930.12 83 179 3.9E-36 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 Gene3D G3DSA:3.90.930.12 1 82 1.5E-29 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0400 ee2023246df4d83195baafe2119f03df 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 34.947 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_0400 ee2023246df4d83195baafe2119f03df 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 Gene3D G3DSA:2.40.30.10 127 206 3.3E-16 T 13-10-2018 Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 201 2.4E-78 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 ProSitePatterns PS00474 Ribosomal protein L3 signature. 99 122 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 Pfam PF00297 Ribosomal protein L3 88 178 1.4E-16 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 Gene3D G3DSA:2.40.50.620 33 91 1.0E-11 T 13-10-2018 Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 SUPERFAMILY SSF50447 1 205 2.3E-70 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0385 796de5ae734e68bb55649ce5a57ef698 206 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 204 35.572 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 15 26 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 12 63 4.8E-13 T 13-10-2018 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 SUPERFAMILY SSF54862 11 63 1.15E-9 T 13-10-2018 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 5.9E-7 T 13-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 PRINTS PR00352 3Fe-4S ferredoxin signature 21 31 5.9E-7 T 13-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 PRINTS PR00352 3Fe-4S ferredoxin signature 10 21 5.9E-7 T 13-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 Spica_1644 acadc062a08f8b47be8629c24c6f2a8d 65 Gene3D G3DSA:3.30.70.20 9 64 2.7E-15 T 13-10-2018 Spica_0592 72010f496461e1e4d3a18ef0f502f0be 81 Gene3D G3DSA:3.40.50.1980 8 27 6.3E-18 T 13-10-2018 Spica_0592 72010f496461e1e4d3a18ef0f502f0be 81 SUPERFAMILY SSF53807 7 80 9.16E-10 T 13-10-2018 Spica_0592 72010f496461e1e4d3a18ef0f502f0be 81 Gene3D G3DSA:1.20.58.2180 28 73 6.3E-18 T 13-10-2018 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 136 570 1.6E-160 T 13-10-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 SMART SM00900 39 113 1.3E-13 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 SUPERFAMILY SSF51905 133 578 4.23E-68 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 Gene3D G3DSA:3.50.50.60 135 572 2.1E-172 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 SUPERFAMILY SSF56425 368 513 4.64E-43 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 Pfam PF04205 FMN-binding domain 39 111 2.5E-13 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 Pfam PF00890 FAD binding domain 136 558 1.4E-97 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 Gene3D G3DSA:3.90.700.10 370 514 2.1E-172 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_2431 deb17f83a5a6d19815aa783e9cbe4984 579 Gene3D G3DSA:3.90.1010.20 49 125 1.1E-6 T 13-10-2018 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Pfam PF00343 Carbohydrate phosphorylase 265 616 5.1E-23 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Pfam PF00343 Carbohydrate phosphorylase 120 185 2.9E-5 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Pfam PF11897 Protein of unknown function (DUF3417) 12 116 5.9E-32 T 13-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Gene3D G3DSA:3.40.50.2000 113 205 9.0E-12 T 13-10-2018 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Gene3D G3DSA:3.40.50.2000 260 410 3.5E-9 T 13-10-2018 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 PIRSF PIRSF000460 1 790 5.1E-274 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 Gene3D G3DSA:3.40.50.2000 411 747 1.3E-42 T 13-10-2018 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 SUPERFAMILY SSF53756 6 738 4.49E-211 T 13-10-2018 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 103 704 6.4E-261 T 13-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spica_0331 cb10cb71d41d7cbb6b81c0185882943c 845 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 594 606 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 Gene3D G3DSA:3.40.50.300 356 592 3.6E-75 T 13-10-2018 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 SMART SM00382 390 577 2.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 SUPERFAMILY SSF52540 358 591 3.01E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 Pfam PF00664 ABC transporter transmembrane region 26 304 1.3E-9 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 Pfam PF00005 ABC transporter 382 533 3.9E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 SUPERFAMILY SSF90123 18 319 4.45E-29 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 Gene3D G3DSA:1.20.1560.10 12 340 2.3E-22 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_1456 2dccfbcb10cf299e53811e651f020bd3 592 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Gene3D G3DSA:3.10.20.600 342 435 1.6E-35 T 13-10-2018 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Gene3D G3DSA:1.20.1440.230 437 537 6.3E-31 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 5 80 3.4E-7 T 13-10-2018 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 452 463 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SUPERFAMILY SSF54862 541 593 1.06E-15 T 13-10-2018 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SUPERFAMILY SSF140490 435 537 4.05E-35 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SUPERFAMILY SSF52833 4 96 9.51E-21 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 441 524 4.0E-31 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Gene3D G3DSA:3.30.70.20 541 596 5.6E-14 T 13-10-2018 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SUPERFAMILY SSF142019 110 350 4.18E-96 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 548 559 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Pfam PF10531 SLBB domain 353 402 5.9E-10 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 329 4.1E-48 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Gene3D G3DSA:3.40.50.11540 163 341 4.4E-79 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SMART SM00928 439 484 6.6E-23 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Pfam PF12838 4Fe-4S dicluster domain 547 592 1.2E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 SUPERFAMILY SSF142984 351 434 1.44E-26 T 13-10-2018 Spica_2774 b9ecf36ccbca804f3bdf447cadf39959 596 Gene3D G3DSA:3.40.30.10 2 100 1.1E-23 T 13-10-2018 Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 Gene3D G3DSA:3.30.930.10 226 536 2.8E-83 T 13-10-2018 Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 229 524 1.0E-99 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 SUPERFAMILY SSF55681 256 526 1.47E-55 T 13-10-2018 Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 SUPERFAMILY SSF46785 10 78 6.18E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 Pfam PF01409 tRNA synthetases class II core domain (F) 256 524 5.2E-77 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Spica_0157 0d8dfef8eead1e008b54fb1476756270 537 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 528 35.997 T 13-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Pfam PF00672 HAMP domain 147 195 2.0E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SMART SM00387 321 434 5.6E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Gene3D G3DSA:1.10.287.130 203 278 6.1E-17 T 13-10-2018 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 433 2.1E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SUPERFAMILY SSF55874 263 432 1.57E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 272 1.1E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 412 2.5E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 373 2.5E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 387 2.5E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 2.5E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SUPERFAMILY SSF158472 147 196 3.92E-8 T 13-10-2018 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SMART SM00388 207 274 7.9E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Gene3D G3DSA:3.30.565.10 280 435 1.3E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 Gene3D G3DSA:1.20.1480.50 118 202 5.5E-8 T 13-10-2018 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SUPERFAMILY SSF47384 202 275 3.14E-15 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2604 8019fd5cee27eaf764bb385918a202cf 439 SMART SM00304 147 199 5.2E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2074 59754975596448cabfbbbe4ce9b001b0 421 Gene3D G3DSA:3.40.190.10 150 414 8.2E-67 T 13-10-2018 Spica_2074 59754975596448cabfbbbe4ce9b001b0 421 Gene3D G3DSA:3.40.190.10 51 380 8.2E-67 T 13-10-2018 Spica_2074 59754975596448cabfbbbe4ce9b001b0 421 SUPERFAMILY SSF53850 27 420 8.01E-59 T 13-10-2018 Spica_2074 59754975596448cabfbbbe4ce9b001b0 421 Pfam PF13416 Bacterial extracellular solute-binding protein 52 359 7.1E-34 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 Gene3D G3DSA:3.40.470.10 47 236 3.5E-73 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 Pfam PF03167 Uracil DNA glycosylase superfamily 72 219 5.9E-45 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 SMART SM00987 72 219 2.5E-39 T 13-10-2018 Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 SMART SM00986 72 219 2.5E-39 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 58 225 3.8E-63 T 13-10-2018 IPR005273 Uracil-DNA glycosylase family 4 Spica_1553 9aaea5f6a03eccac8ee92aa5aecaca90 240 SUPERFAMILY SSF52141 45 226 6.87E-62 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_2762 c838a6ba5923e6ad2100547d9fe5212e 198 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 19 192 3.1E-9 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related Spica_2762 c838a6ba5923e6ad2100547d9fe5212e 198 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 17 192 2.8E-11 T 13-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 Gene3D G3DSA:3.40.50.300 3 239 1.9E-42 T 13-10-2018 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 Gene3D G3DSA:3.40.50.300 254 488 3.6E-47 T 13-10-2018 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 Pfam PF00005 ABC transporter 265 419 4.5E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 Pfam PF00005 ABC transporter 27 166 1.4E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 SUPERFAMILY SSF52540 10 224 3.04E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 SUPERFAMILY SSF52540 238 477 8.68E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 SMART SM00382 36 244 1.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2817 c8357ed24a59e66646d926ec99c24ac8 490 SMART SM00382 274 467 3.8E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0399 f98479743034bbc65e5db2b23e97f31e 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.115 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0399 f98479743034bbc65e5db2b23e97f31e 132 Gene3D G3DSA:3.30.1370.30 4 77 5.6E-30 T 13-10-2018 Spica_0399 f98479743034bbc65e5db2b23e97f31e 132 SUPERFAMILY SSF56047 3 132 6.67E-46 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0399 f98479743034bbc65e5db2b23e97f31e 132 Gene3D G3DSA:3.30.1490.10 78 132 9.3E-23 T 13-10-2018 Spica_0399 f98479743034bbc65e5db2b23e97f31e 132 Pfam PF00410 Ribosomal protein S8 5 132 5.1E-51 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_2429 4b8611da0da3f391c00be421c504b17e 190 Pfam PF01381 Helix-turn-helix 11 63 3.3E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2429 4b8611da0da3f391c00be421c504b17e 190 SUPERFAMILY SSF47413 3 73 7.32E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2429 4b8611da0da3f391c00be421c504b17e 190 Pfam PF07883 Cupin domain 130 185 1.9E-12 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_2429 4b8611da0da3f391c00be421c504b17e 190 SMART SM00530 10 65 2.2E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2429 4b8611da0da3f391c00be421c504b17e 190 Gene3D G3DSA:2.60.120.10 75 187 1.9E-28 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2429 4b8611da0da3f391c00be421c504b17e 190 Gene3D G3DSA:1.10.260.40 5 70 7.6E-15 T 13-10-2018 Spica_2429 4b8611da0da3f391c00be421c504b17e 190 SUPERFAMILY SSF51182 58 189 1.19E-24 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Gene3D G3DSA:3.30.56.10 1 82 3.9E-19 T 13-10-2018 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Pfam PF03484 tRNA synthetase B5 domain 301 370 4.1E-12 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Gene3D G3DSA:3.30.56.10 299 372 3.8E-10 T 13-10-2018 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Gene3D G3DSA:3.30.930.10 391 580 4.6E-41 T 13-10-2018 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 SUPERFAMILY SSF46955 299 371 1.37E-7 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 SMART SM00873 110 270 5.2E-5 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 SMART SM00874 296 374 1.9E-9 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 SUPERFAMILY SSF55681 390 580 1.12E-35 T 13-10-2018 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 577 30.335 T 13-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 580 9.6E-153 T 13-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Spica_0156 1ddcceaec746967e4dbfcb19a1a9a11e 580 Gene3D G3DSA:3.50.40.10 92 285 3.3E-54 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 285 6.7E-55 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 297 29.19 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 Gene3D G3DSA:3.30.70.890 170 295 2.8E-20 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 Gene3D G3DSA:3.30.230.10 2 166 9.1E-54 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 Pfam PF08544 GHMP kinases C terminal 245 286 9.0E-6 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 SUPERFAMILY SSF55060 170 290 2.21E-17 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 SUPERFAMILY SSF54211 5 165 6.07E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 Pfam PF00288 GHMP kinases N terminal domain 94 150 1.1E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spica_0790 4684a04f43592f7bb1f3a5c833c1eedd 307 PIRSF PIRSF010376 4 305 3.2E-74 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Spica_0657 afdd3501197dfdd85614222a4e2dd962 154 Gene3D G3DSA:3.40.30.10 2 152 7.2E-52 T 13-10-2018 Spica_0657 afdd3501197dfdd85614222a4e2dd962 154 Pfam PF00578 AhpC/TSA family 4 132 3.7E-38 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_0657 afdd3501197dfdd85614222a4e2dd962 154 SUPERFAMILY SSF52833 1 152 2.28E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0657 afdd3501197dfdd85614222a4e2dd962 154 PIRSF PIRSF000239 1 153 1.1E-23 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Pfam PF00889 Elongation factor TS 70 282 1.3E-53 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Gene3D G3DSA:3.30.479.20 143 281 3.0E-39 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 SUPERFAMILY SSF54713 141 281 4.32E-31 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Gene3D G3DSA:3.30.479.20 56 136 5.1E-17 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 SUPERFAMILY SSF54713 56 133 1.44E-15 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Hamap MF_00050 Elongation factor Ts [tsf]. 1 282 52.131 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 2 281 9.8E-74 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Gene3D G3DSA:1.10.286.20 192 240 3.0E-39 T 13-10-2018 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 SUPERFAMILY SSF46934 2 55 4.39E-16 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 Gene3D G3DSA:1.10.8.10 1 55 2.5E-22 T 13-10-2018 Spica_1416 70d16fdb70b0a3592fa5d6e85834961f 282 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_2353 75d8bae623c7fd0175f1e559a54e271c 122 Pfam PF14559 Tetratricopeptide repeat 40 99 1.9E-7 T 13-10-2018 Spica_2353 75d8bae623c7fd0175f1e559a54e271c 122 SUPERFAMILY SSF48452 35 112 4.27E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2353 75d8bae623c7fd0175f1e559a54e271c 122 Gene3D G3DSA:1.25.40.10 16 115 2.1E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 252 377 3.6E-20 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Gene3D G3DSA:3.30.1360.120 2 129 1.0E-37 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 16 380 3.5E-92 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 SUPERFAMILY SSF52540 104 423 4.84E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 10 536 30.325 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Gene3D G3DSA:3.40.50.300 250 464 1.2E-85 T 13-10-2018 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 SUPERFAMILY SSF103025 9 129 2.39E-33 T 13-10-2018 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Gene3D G3DSA:1.20.120.430 130 536 1.2E-85 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Pfam PF10396 GTP-binding protein TrmE N-terminus 11 129 4.3E-32 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Pfam PF12631 MnmE helical domain 132 533 4.1E-37 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 Spica_2098 d0de289c9e06db60cd3bfd77d72b61a1 536 Pfam PF01926 50S ribosome-binding GTPase 252 372 3.4E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0574 80ae4387b9e3b6e0674abd173aba83fc 378 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 238 317 8.1E-11 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Spica_0574 80ae4387b9e3b6e0674abd173aba83fc 378 SUPERFAMILY SSF53756 87 320 3.59E-19 T 13-10-2018 Spica_0574 80ae4387b9e3b6e0674abd173aba83fc 378 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 23 178 1.5E-4 T 13-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 Spica_0574 80ae4387b9e3b6e0674abd173aba83fc 378 Gene3D G3DSA:3.40.50.2000 194 348 8.5E-18 T 13-10-2018 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 SUPERFAMILY SSF56784 808 1013 9.65E-41 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 715 752 1.0E-4 T 13-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Gene3D G3DSA:1.50.10.10 323 691 4.5E-138 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Gene3D G3DSA:1.10.150.240 820 896 6.9E-59 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 SUPERFAMILY SSF74650 8 269 1.0E-48 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 13 269 6.1E-52 T 13-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 938 996 8.7E-14 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Gene3D G3DSA:2.60.420.10 692 765 7.8E-13 T 13-10-2018 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 329 702 5.8E-125 T 13-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Pfam PF13419 Haloacid dehalogenase-like hydrolase 810 996 4.6E-20 T 13-10-2018 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 807 997 6.0E-69 T 13-10-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 SUPERFAMILY SSF48208 284 752 1.81E-122 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Gene3D G3DSA:3.40.50.1000 809 1007 6.9E-59 T 13-10-2018 IPR023214 HAD superfamily Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 808 996 2.3E-53 T 13-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase Spica_0831 8e386231ae33c3e787bc635744af2a15 1025 Gene3D G3DSA:2.70.98.40 5 273 1.0E-57 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0763 3671a98671146609f67a81c7eb364765 356 SUPERFAMILY SSF53822 62 331 2.54E-46 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0763 3671a98671146609f67a81c7eb364765 356 Gene3D G3DSA:1.10.260.40 1 60 5.4E-17 T 13-10-2018 Spica_0763 3671a98671146609f67a81c7eb364765 356 SMART SM00354 2 73 2.9E-13 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0763 3671a98671146609f67a81c7eb364765 356 SUPERFAMILY SSF47413 2 59 1.03E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0763 3671a98671146609f67a81c7eb364765 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.6E-12 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0763 3671a98671146609f67a81c7eb364765 356 Gene3D G3DSA:3.40.50.2300 159 335 3.3E-57 T 13-10-2018 Spica_0763 3671a98671146609f67a81c7eb364765 356 Gene3D G3DSA:3.40.50.2300 77 329 3.3E-57 T 13-10-2018 Spica_0763 3671a98671146609f67a81c7eb364765 356 Pfam PF13377 Periplasmic binding protein-like domain 170 337 1.8E-31 T 13-10-2018 Spica_0959 dca565cacd2815efac025120e75cf077 451 Pfam PF01584 CheW-like domain 34 170 1.2E-33 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0959 dca565cacd2815efac025120e75cf077 451 SUPERFAMILY SSF53335 274 433 1.19E-20 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0959 dca565cacd2815efac025120e75cf077 451 PRINTS PR00996 Glutamate methyltransferase family signature 389 403 1.4E-8 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0959 dca565cacd2815efac025120e75cf077 451 PRINTS PR00996 Glutamate methyltransferase family signature 295 315 1.4E-8 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0959 dca565cacd2815efac025120e75cf077 451 PRINTS PR00996 Glutamate methyltransferase family signature 408 431 1.4E-8 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0959 dca565cacd2815efac025120e75cf077 451 SMART SM00138 207 450 4.9E-9 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0959 dca565cacd2815efac025120e75cf077 451 Pfam PF01739 CheR methyltransferase, SAM binding domain 280 433 4.0E-35 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_0959 dca565cacd2815efac025120e75cf077 451 Gene3D G3DSA:3.40.50.150 273 448 2.9E-27 T 13-10-2018 Spica_0959 dca565cacd2815efac025120e75cf077 451 SUPERFAMILY SSF50341 32 170 3.14E-33 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_0959 dca565cacd2815efac025120e75cf077 451 Gene3D G3DSA:2.30.30.40 35 162 1.3E-35 T 13-10-2018 Spica_0959 dca565cacd2815efac025120e75cf077 451 Gene3D G3DSA:2.40.50.180 50 167 1.3E-35 T 13-10-2018 Spica_0959 dca565cacd2815efac025120e75cf077 451 SMART SM00260 29 168 1.7E-44 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 SUPERFAMILY SSF51735 8 135 3.03E-17 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 Pfam PF02719 Polysaccharide biosynthesis protein 149 436 1.7E-113 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 Gene3D G3DSA:3.40.50.720 144 454 8.5E-108 T 13-10-2018 Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 Pfam PF13727 CoA-binding domain 11 95 2.0E-7 T 13-10-2018 Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 Gene3D G3DSA:3.40.50.720 4 130 2.0E-30 T 13-10-2018 Spica_1447 1cbc245400dd2aca8f1c33426dcfd56e 493 SUPERFAMILY SSF51735 146 414 7.2E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1352 70f0264438b847986e1f35a40abc18b4 154 Pfam PF02576 RimP N-terminal domain 15 85 7.6E-12 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal Spica_1352 70f0264438b847986e1f35a40abc18b4 154 SUPERFAMILY SSF74942 86 148 7.32E-5 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily Spica_1352 70f0264438b847986e1f35a40abc18b4 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 9 150 15.979 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 Spica_1352 70f0264438b847986e1f35a40abc18b4 154 Gene3D G3DSA:3.30.300.70 8 82 1.0E-6 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily Spica_1352 70f0264438b847986e1f35a40abc18b4 154 SUPERFAMILY SSF75420 6 85 1.7E-10 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily Spica_1329 0befb56e74220d86ed8906b6bf256a69 164 Gene3D G3DSA:1.20.120.330 39 156 6.3E-7 T 13-10-2018 Spica_1329 0befb56e74220d86ed8906b6bf256a69 164 SUPERFAMILY SSF81593 44 131 5.89E-15 T 13-10-2018 Spica_2749 a7940386516b368b854de8cec2b93c0e 135 SUPERFAMILY SSF55874 35 130 4.98E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2749 a7940386516b368b854de8cec2b93c0e 135 SMART SM00387 35 132 2.5E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2749 a7940386516b368b854de8cec2b93c0e 135 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 131 1.4E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2749 a7940386516b368b854de8cec2b93c0e 135 Gene3D G3DSA:3.30.565.10 1 133 2.3E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2749 a7940386516b368b854de8cec2b93c0e 135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 75 89 1.2E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2749 a7940386516b368b854de8cec2b93c0e 135 PRINTS PR00344 Bacterial sensor protein C-terminal signature 94 112 1.2E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 243 259 2.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 173 201 2.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 334 360 2.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 149 162 2.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 225 242 2.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 Gene3D G3DSA:3.30.360.10 183 479 1.9E-171 T 13-10-2018 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 PIRSF PIRSF000110 8 492 7.2E-171 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 23 193 1.9E-50 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 Gene3D G3DSA:3.40.50.720 22 439 1.9E-171 T 13-10-2018 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 196 490 1.4E-114 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 19 491 6.4E-181 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 SUPERFAMILY SSF51735 14 196 2.76E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 18 491 82.77 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 183 189 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Spica_0962 5a4671e6242c4947c53e4b6185a6f709 492 SUPERFAMILY SSF55347 183 490 5.89E-115 T 13-10-2018 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 ProSitePatterns PS00893 Nudix box signature. 184 205 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 119 148 2.6E-7 T 13-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 Pfam PF00293 NUDIX domain 153 258 1.1E-16 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 Gene3D G3DSA:3.90.79.10 150 279 1.6E-38 T 13-10-2018 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 SUPERFAMILY SSF55811 104 274 1.08E-39 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_1189 b1baea4369716b5e5052ce802a81fa0a 280 Gene3D G3DSA:3.90.79.20 2 149 1.6E-12 T 13-10-2018 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 SUPERFAMILY SSF56519 49 186 1.96E-29 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 SUPERFAMILY SSF54184 569 620 6.54E-8 T 13-10-2018 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Pfam PF03793 PASTA domain 569 620 3.0E-5 T 13-10-2018 IPR005543 PASTA domain Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Pfam PF03717 Penicillin-binding Protein dimerisation domain 50 185 2.9E-12 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 SUPERFAMILY SSF56601 194 541 6.24E-82 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Gene3D G3DSA:3.90.1310.30 44 198 2.5E-28 T 13-10-2018 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Gene3D G3DSA:3.40.710.10 255 452 1.6E-95 T 13-10-2018 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Pfam PF00905 Penicillin binding protein transpeptidase domain 221 531 1.6E-62 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spica_1218 8fc56f4925fb179bf25d0b132554efe4 621 Gene3D G3DSA:3.30.450.330 199 537 1.6E-95 T 13-10-2018 Spica_0353 183463fd6752b71a892379d27695a77c 429 SUPERFAMILY SSF53850 31 428 1.14E-47 T 13-10-2018 Spica_0353 183463fd6752b71a892379d27695a77c 429 Gene3D G3DSA:3.40.190.10 150 418 2.6E-60 T 13-10-2018 Spica_0353 183463fd6752b71a892379d27695a77c 429 Gene3D G3DSA:3.40.190.10 55 388 2.6E-60 T 13-10-2018 Spica_0353 183463fd6752b71a892379d27695a77c 429 Pfam PF13416 Bacterial extracellular solute-binding protein 55 364 1.9E-26 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 145 159 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 Gene3D G3DSA:3.10.290.10 7 68 7.0E-9 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 313 1.4E-72 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 SUPERFAMILY SSF55120 71 312 1.87E-65 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 Gene3D G3DSA:3.30.2350.10 80 315 1.1E-67 T 13-10-2018 Spica_1583 75a084ac97a47c83b9f73afdc674b4e3 315 Pfam PF00849 RNA pseudouridylate synthase 88 252 1.1E-32 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 SUPERFAMILY SSF46689 459 507 3.58E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 Gene3D G3DSA:3.40.50.12740 3 159 2.2E-32 T 13-10-2018 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 SUPERFAMILY SSF52172 1 171 1.71E-35 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 SMART SM00448 2 117 2.4E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 475 490 1.1E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 490 506 1.1E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 SMART SM00342 423 506 4.7E-29 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 Pfam PF12833 Helix-turn-helix domain 430 506 7.6E-20 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 460 502 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 SUPERFAMILY SSF46689 407 452 7.88E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 Pfam PF00072 Response regulator receiver domain 4 117 7.3E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 Gene3D G3DSA:1.10.10.60 404 456 1.3E-11 T 13-10-2018 Spica_2011 c30b199b0082ebb6de07b270949b72ee 519 Gene3D G3DSA:1.10.10.60 457 512 2.3E-17 T 13-10-2018 Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 Gene3D G3DSA:3.40.50.12780 2 440 2.0E-124 T 13-10-2018 Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 4.6E-16 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 Pfam PF00501 AMP-binding enzyme 19 450 2.1E-112 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 SUPERFAMILY SSF56801 12 546 9.94E-162 T 13-10-2018 Spica_2428 f9ce7746066d37f4a23494067fceb76c 556 Gene3D G3DSA:3.30.300.30 444 546 5.8E-31 T 13-10-2018 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 333 348 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 5.4E-22 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 SUPERFAMILY SSF53822 27 370 1.3E-99 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 Gene3D G3DSA:3.40.50.2300 148 276 3.4E-105 T 13-10-2018 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 Gene3D G3DSA:3.40.50.2300 30 349 3.4E-105 T 13-10-2018 Spica_0413 d0178925b92f8ab5249b7252fc6f862b 372 Pfam PF13458 Periplasmic binding protein 28 367 5.6E-67 T 13-10-2018 IPR028081 Leucine-binding protein domain Spica_1214 cbfa151855ab42ffedb1525c2249b663 383 SUPERFAMILY SSF109604 151 309 1.31E-18 T 13-10-2018 Spica_1214 cbfa151855ab42ffedb1525c2249b663 383 Gene3D G3DSA:1.10.3210.10 3 314 4.6E-53 T 13-10-2018 Spica_1214 cbfa151855ab42ffedb1525c2249b663 383 SMART SM00471 148 283 1.8E-5 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1214 cbfa151855ab42ffedb1525c2249b663 383 Pfam PF13487 HD domain 205 265 1.8E-12 T 13-10-2018 Spica_0636 fbae2edc916e16f9a53a5ce682cca368 297 SUPERFAMILY SSF161098 14 297 7.72E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0636 fbae2edc916e16f9a53a5ce682cca368 297 Gene3D G3DSA:1.10.3720.10 7 288 5.2E-59 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0636 fbae2edc916e16f9a53a5ce682cca368 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 289 9.1E-10 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0130 e3ce7c567036da5ddd9146677f883755 397 SUPERFAMILY SSF53613 75 369 1.17E-35 T 13-10-2018 IPR029056 Ribokinase-like Spica_0130 e3ce7c567036da5ddd9146677f883755 397 Gene3D G3DSA:3.40.1190.20 58 377 4.8E-43 T 13-10-2018 IPR029056 Ribokinase-like Spica_0130 e3ce7c567036da5ddd9146677f883755 397 Pfam PF00294 pfkB family carbohydrate kinase 87 368 1.7E-22 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_1162 d308d916d0a134620efce255d80080f1 286 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 231 1.2E-49 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_1162 d308d916d0a134620efce255d80080f1 286 Hamap MF_00258 Glutamate racemase [murI]. 4 261 27.388 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_1162 d308d916d0a134620efce255d80080f1 286 SUPERFAMILY SSF53681 110 227 1.57E-23 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_1162 d308d916d0a134620efce255d80080f1 286 Gene3D G3DSA:3.40.50.1860 9 231 4.0E-61 T 13-10-2018 Spica_1162 d308d916d0a134620efce255d80080f1 286 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 13-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_1162 d308d916d0a134620efce255d80080f1 286 SUPERFAMILY SSF53681 5 108 1.44E-22 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_1162 d308d916d0a134620efce255d80080f1 286 Gene3D G3DSA:3.40.50.1860 97 210 4.0E-61 T 13-10-2018 Spica_1162 d308d916d0a134620efce255d80080f1 286 Pfam PF01177 Asp/Glu/Hydantoin racemase 11 210 2.8E-20 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SUPERFAMILY SSF47226 164 268 1.83E-27 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Gene3D G3DSA:2.40.50.180 635 700 1.0E-25 T 13-10-2018 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SMART SM01231 363 424 1.6E-4 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SUPERFAMILY SSF160246 297 356 9.94E-7 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Pfam PF01584 CheW-like domain 618 748 2.4E-13 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 611 1.3E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SUPERFAMILY SSF55874 426 610 1.19E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 365 419 3.8E-7 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SMART SM00260 604 746 2.4E-13 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 1.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 PRINTS PR00344 Bacterial sensor protein C-terminal signature 596 609 1.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 590 1.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SMART SM00073 164 261 1.6E-21 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Gene3D G3DSA:1.10.287.560 363 423 1.3E-8 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Gene3D G3DSA:2.30.30.40 612 741 1.0E-25 T 13-10-2018 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Pfam PF01627 Hpt domain 167 266 3.9E-17 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Gene3D G3DSA:1.20.120.160 160 294 6.6E-34 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SUPERFAMILY SSF47384 365 424 2.51E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SMART SM00387 469 612 1.6E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 SUPERFAMILY SSF50341 611 745 9.16E-18 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_2344 9b596298b9fe8030f9c54d522e5eb012 750 Gene3D G3DSA:3.30.565.10 424 611 1.1E-56 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 258 554 15.267 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 260 519 1.0E-38 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 PIRSF PIRSF017184 1 552 1.3E-72 T 13-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 Pfam PF01256 Carbohydrate kinase 282 535 6.1E-38 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 SUPERFAMILY SSF64153 1 243 2.88E-30 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 Gene3D G3DSA:3.40.50.10260 3 244 1.5E-36 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 Gene3D G3DSA:3.40.1190.20 253 550 1.5E-46 T 13-10-2018 IPR029056 Ribokinase-like Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 Pfam PF03853 YjeF-related protein N-terminus 26 218 1.2E-22 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 Spica_1441 dcf0ee27e9f1ac6032bfbb8b7b7ea0e0 556 SUPERFAMILY SSF53613 268 541 4.76E-36 T 13-10-2018 IPR029056 Ribokinase-like Spica_0175 3a67927beace623a63019c3e93aec708 540 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 197 532 35.766 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Spica_0175 3a67927beace623a63019c3e93aec708 540 Pfam PF02885 Glycosyl transferase family, helical bundle domain 200 256 4.3E-13 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.4E-6 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.4E-6 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 Gene3D G3DSA:1.20.970.10 199 261 3.9E-17 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 200 530 5.6E-108 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Spica_0175 3a67927beace623a63019c3e93aec708 540 Pfam PF00117 Glutamine amidotransferase class-I 3 186 4.2E-42 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_0175 3a67927beace623a63019c3e93aec708 540 Gene3D G3DSA:3.40.50.880 1 188 1.0E-53 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0175 3a67927beace623a63019c3e93aec708 540 Gene3D G3DSA:3.40.1030.10 268 539 4.9E-98 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0175 3a67927beace623a63019c3e93aec708 540 SUPERFAMILY SSF52418 271 530 9.03E-84 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0175 3a67927beace623a63019c3e93aec708 540 SUPERFAMILY SSF47648 196 259 9.29E-12 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.2E-12 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 1.2E-12 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 1.2E-12 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 SUPERFAMILY SSF52317 1 190 4.94E-46 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 75 86 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 48 57 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 100 108 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 120 132 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 PRINTS PR00097 Anthranilate synthase component II signature 165 178 5.4E-28 T 13-10-2018 Spica_0175 3a67927beace623a63019c3e93aec708 540 Pfam PF00591 Glycosyl transferase family, a/b domain 271 521 9.1E-81 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0175 3a67927beace623a63019c3e93aec708 540 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 5.8E-65 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 121 5.0E-20 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Gene3D G3DSA:3.40.950.10 271 507 7.8E-158 T 13-10-2018 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Gene3D G3DSA:3.10.20.740 1 123 5.2E-44 T 13-10-2018 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 138 516 2.3E-159 T 13-10-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Pfam PF02256 Iron hydrogenase small subunit 521 576 3.2E-26 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Gene3D G3DSA:3.40.50.1780 205 516 7.8E-158 T 13-10-2018 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 SUPERFAMILY SSF53920 189 574 4.84E-127 T 13-10-2018 IPR009016 Iron hydrogenase Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Pfam PF13187 4Fe-4S dicluster domain 145 204 1.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 224 513 1.3E-94 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Gene3D G3DSA:4.10.260.20 519 581 1.3E-19 T 13-10-2018 IPR036991 Iron hydrogenase, small subunit superfamily Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Gene3D G3DSA:3.30.70.20 141 204 7.8E-158 T 13-10-2018 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 SMART SM00902 518 577 2.1E-24 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 SUPERFAMILY SSF54862 76 213 1.05E-35 T 13-10-2018 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 SUPERFAMILY SSF54292 1 74 1.48E-20 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 SMART SM00929 83 123 4.0E-20 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2773 004c2dafe30e81328e2b88242ff9b845 581 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 75 1.7E-18 T 13-10-2018 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 Pfam PF00813 FliP family 84 278 1.6E-75 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 152 166 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 182 194 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 140 152 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 204 216 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 80 89 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 272 282 3.0E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 84 282 5.5E-88 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 259 271 - T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 101 121 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 232 253 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 82 101 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 211 231 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 121 140 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_1529 9eee0c4353ccc09ee6920941f78a8e5c 283 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 256 281 8.6E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 183 37.571 T 13-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 Gene3D G3DSA:1.10.10.10 101 186 1.4E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 Gene3D G3DSA:3.30.160.70 1 96 4.1E-9 T 13-10-2018 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 102 182 1.3E-31 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 SUPERFAMILY SSF53155 3 107 1.02E-9 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 SUPERFAMILY SSF46767 101 183 3.53E-31 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 153 159 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Spica_2363 999c27fd41cf3e7c285f7e5a1ba76208 188 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 103 183 7.0E-33 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Spica_0355 d740b82be04f8fe12fecacd0a2c94acd 370 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 178 363 3.8E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0355 d740b82be04f8fe12fecacd0a2c94acd 370 SUPERFAMILY SSF161098 15 370 1.72E-57 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0355 d740b82be04f8fe12fecacd0a2c94acd 370 Gene3D G3DSA:1.10.3720.10 130 361 1.0E-44 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2540 294b77a34b118b01f7dd5b9b4e2f4c34 292 SUPERFAMILY SSF69593 53 284 3.92E-24 T 13-10-2018 Spica_2540 294b77a34b118b01f7dd5b9b4e2f4c34 292 Pfam PF01553 Acyltransferase 64 195 3.4E-5 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_2540 294b77a34b118b01f7dd5b9b4e2f4c34 292 Gene3D G3DSA:3.40.1130.10 41 213 2.9E-9 T 13-10-2018 Spica_2540 294b77a34b118b01f7dd5b9b4e2f4c34 292 SMART SM00563 75 218 2.6E-4 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 Pfam PF00248 Aldo/keto reductase family 16 317 1.2E-65 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 258 270 2.8E-12 T 13-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 112 122 2.8E-12 T 13-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 208 214 2.8E-12 T 13-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 271 284 2.8E-12 T 13-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 163 182 2.8E-12 T 13-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 Gene3D G3DSA:3.20.20.100 1 320 1.1E-114 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_0811 d63c4a360bd965f22ec8d4f595a3604e 328 SUPERFAMILY SSF51430 1 317 1.19E-93 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_2226 a4c4ea2d1e93d195b53fc7d0f1ccbecb 475 SUPERFAMILY SSF103365 8 475 9.81E-156 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Spica_2226 a4c4ea2d1e93d195b53fc7d0f1ccbecb 475 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 45 74 - T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Spica_2226 a4c4ea2d1e93d195b53fc7d0f1ccbecb 475 Gene3D G3DSA:3.90.1860.10 2 475 5.0E-174 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Spica_2226 a4c4ea2d1e93d195b53fc7d0f1ccbecb 475 Pfam PF01139 tRNA-splicing ligase RtcB 45 475 2.9E-147 T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 Pfam PF03315 Serine dehydratase beta chain 13 144 1.6E-13 T 13-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 SUPERFAMILY SSF55021 161 231 2.78E-14 T 13-10-2018 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 Gene3D G3DSA:3.30.70.260 154 231 1.2E-12 T 13-10-2018 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 9 219 5.1E-58 T 13-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 SUPERFAMILY SSF143548 25 150 6.54E-25 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 PIRSF PIRSF036692 7 233 8.9E-71 T 13-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 Gene3D G3DSA:3.30.1330.90 19 150 1.8E-18 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Spica_0428 d2a0d478fcb28e23ced85aea585a4304 237 Pfam PF01842 ACT domain 162 223 8.4E-9 T 13-10-2018 IPR002912 ACT domain Spica_1805 95826bf27001f3b548a719bb6a99ee41 343 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 339 3.9E-26 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_1805 95826bf27001f3b548a719bb6a99ee41 343 Gene3D G3DSA:3.40.640.10 1 226 1.4E-28 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1805 95826bf27001f3b548a719bb6a99ee41 343 SUPERFAMILY SSF53383 2 340 2.08E-34 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1805 95826bf27001f3b548a719bb6a99ee41 343 Gene3D G3DSA:3.90.1150.10 229 342 4.6E-7 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0618 891056fb922cc538f7abe322dff3d96e 116 SUPERFAMILY SSF51182 40 93 3.76E-8 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0618 891056fb922cc538f7abe322dff3d96e 116 Gene3D G3DSA:2.60.120.10 4 116 1.2E-7 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SMART SM00387 422 566 3.5E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Gene3D G3DSA:2.30.30.40 566 692 4.3E-34 T 13-10-2018 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SUPERFAMILY SSF55874 379 564 4.98E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Gene3D G3DSA:2.40.50.180 589 651 4.3E-34 T 13-10-2018 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Pfam PF01627 Hpt domain 16 99 6.0E-18 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SUPERFAMILY SSF160246 252 312 2.56E-5 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SUPERFAMILY SSF50341 565 695 2.22E-27 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Pfam PF01584 CheW-like domain 571 697 1.0E-22 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Gene3D G3DSA:1.10.287.560 317 377 8.9E-11 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 565 2.0E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SMART SM00073 10 108 1.1E-33 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Gene3D G3DSA:3.30.565.10 378 565 1.1E-55 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SUPERFAMILY SSF47384 319 378 8.63E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SMART SM01231 317 377 4.8E-14 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 319 376 2.4E-8 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 563 8.8E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 481 8.8E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 544 8.8E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 520 8.8E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SMART SM00260 558 696 5.0E-31 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 Gene3D G3DSA:1.20.120.160 9 150 2.0E-36 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_0798 29b92c61c0e2b8bfcd9aa2e8148be06f 710 SUPERFAMILY SSF47226 12 121 4.84E-29 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_0946 846fcc19064e8956fdf661380d196860 617 SMART SM00955 241 514 9.8E-62 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Spica_0946 846fcc19064e8956fdf661380d196860 617 Pfam PF00773 RNB domain 241 447 1.1E-32 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Spica_0946 846fcc19064e8956fdf661380d196860 617 Gene3D G3DSA:2.40.50.140 556 614 3.4E-7 T 13-10-2018 Spica_0946 846fcc19064e8956fdf661380d196860 617 SUPERFAMILY SSF50249 560 614 3.08E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0946 846fcc19064e8956fdf661380d196860 617 Pfam PF00773 RNB domain 462 513 4.2E-14 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Spica_0946 846fcc19064e8956fdf661380d196860 617 SUPERFAMILY SSF50249 190 556 1.94E-76 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0946 846fcc19064e8956fdf661380d196860 617 Gene3D G3DSA:1.10.10.10 164 228 1.1E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 SUPERFAMILY SSF55785 317 420 1.45E-10 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 Pfam PF04282 Family of unknown function (DUF438) 15 80 1.1E-27 T 13-10-2018 IPR007380 Domain of unknown function DUF438 Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 Pfam PF13596 PAS domain 320 425 9.6E-30 T 13-10-2018 Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 Pfam PF01814 Hemerythrin HHE cation binding domain 91 220 4.1E-15 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 Gene3D G3DSA:1.20.120.520 77 235 1.2E-9 T 13-10-2018 Spica_0995 0b0eef67fddc71b8b1838300ed5579b3 440 Gene3D G3DSA:3.30.450.20 305 436 3.6E-43 T 13-10-2018 Spica_0360 aa01722c38436c2c0158f35251edc0de 296 SUPERFAMILY SSF51735 11 249 2.42E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 169 2.4E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 2.4E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.4E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 2.4E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 Pfam PF00106 short chain dehydrogenase 14 222 3.6E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 Gene3D G3DSA:3.40.50.720 2 278 1.5E-46 T 13-10-2018 Spica_0360 aa01722c38436c2c0158f35251edc0de 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 166 194 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 167 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 aa01722c38436c2c0158f35251edc0de 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 108 119 2.6E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 SUPERFAMILY SSF55681 2 246 9.44E-75 T 13-10-2018 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Gene3D G3DSA:3.30.930.10 1 243 2.1E-96 T 13-10-2018 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 SUPERFAMILY SSF101353 247 445 1.16E-61 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 595 96.92 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 SMART SM00863 548 591 1.1E-17 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Gene3D G3DSA:3.30.980.10 457 592 9.2E-52 T 13-10-2018 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 SUPERFAMILY SSF55186 456 593 1.83E-45 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 442 1.2E-138 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Gene3D G3DSA:3.30.54.20 519 572 9.2E-52 T 13-10-2018 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 4.2E-23 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 PRINTS PR00980 Alanyl-tRNA synthetase signature 70 81 4.2E-23 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 PRINTS PR00980 Alanyl-tRNA synthetase signature 200 211 4.2E-23 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 4.2E-23 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 PRINTS PR00980 Alanyl-tRNA synthetase signature 227 240 4.2E-23 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Pfam PF01411 tRNA synthetases class II (A) 5 444 4.2E-141 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Spica_0922 02c35ea53c453b2045346d54ed63a20f 595 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 548 590 1.6E-16 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 9 431 5.5E-149 T 13-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 193 206 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 369 382 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 313 324 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 131 146 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 117 130 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 PRINTS PR00415 Aconitase family signature 207 220 6.0E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 SUPERFAMILY SSF53732 5 434 2.22E-139 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 Pfam PF00330 Aconitase family (aconitate hydratase) 12 427 1.2E-104 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 Gene3D G3DSA:3.30.499.20 9 287 5.1E-90 T 13-10-2018 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 ProSitePatterns PS01244 Aconitase family signature 2. 369 382 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 ProSitePatterns PS00450 Aconitase family signature 1. 309 325 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 8 433 4.6E-128 T 13-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Spica_0939 f9a70883b275b7e523b8d60bc09045e0 436 Gene3D G3DSA:3.30.499.10 292 436 4.8E-55 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:3.40.50.2300 567 699 2.8E-40 T 13-10-2018 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Pfam PF00072 Response regulator receiver domain 403 521 1.1E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Pfam PF00072 Response regulator receiver domain 573 681 5.3E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 383 3.3E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SMART SM00387 270 385 2.9E-41 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SMART SM00073 739 836 5.9E-4 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF47226 711 830 7.98E-21 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:1.10.287.130 132 221 4.5E-27 T 13-10-2018 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF52172 569 687 1.57E-37 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Pfam PF01627 Hpt domain 749 822 1.9E-11 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:3.30.450.20 15 131 1.4E-7 T 13-10-2018 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF55874 212 383 2.88E-48 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF55785 17 117 6.49E-8 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SMART SM00448 570 682 3.0E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SMART SM00448 401 521 4.5E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 382 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:1.20.120.160 726 836 1.3E-19 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SMART SM00388 158 223 2.7E-24 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF52172 401 522 2.28E-19 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Pfam PF00512 His Kinase A (phospho-acceptor) domain 159 223 9.1E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 SUPERFAMILY SSF47384 145 224 4.32E-22 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:3.30.565.10 222 388 9.7E-51 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2371 cf586e9d66310b76610d6eb23d8bbd68 837 Gene3D G3DSA:3.40.50.2300 393 527 5.9E-22 T 13-10-2018 Spica_1925 f23ca037d564212ec2de7aebab7f56fc 228 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 202 2.5E-36 T 13-10-2018 IPR013343 CRISPR-associated protein Cas4 Spica_1925 f23ca037d564212ec2de7aebab7f56fc 228 Gene3D G3DSA:3.90.320.10 9 202 2.2E-7 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Spica_1925 f23ca037d564212ec2de7aebab7f56fc 228 Pfam PF01930 Domain of unknown function DUF83 13 202 5.2E-36 T 13-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 552 562 - T 13-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Gene3D G3DSA:1.10.150.380 289 406 9.7E-23 T 13-10-2018 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 SUPERFAMILY SSF55931 5 284 1.11E-42 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Pfam PF02934 GatB/GatE catalytic domain 6 276 7.3E-35 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 SUPERFAMILY SSF53774 463 793 1.2E-33 T 13-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Pfam PF02637 GatB domain 320 467 4.3E-32 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 PRINTS PR00139 Asparaginase/glutaminase family signature 472 483 8.2E-7 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 PRINTS PR00139 Asparaginase/glutaminase family signature 551 569 8.2E-7 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 SMART SM00870 471 787 5.8E-8 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Pfam PF00710 Asparaginase, N-terminal 472 625 6.6E-22 T 13-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 SMART SM00845 320 467 3.4E-38 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Gene3D G3DSA:1.10.10.410 407 468 2.9E-15 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Gene3D G3DSA:3.40.50.40 673 795 2.5E-11 T 13-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 67 73 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 SUPERFAMILY SSF89095 289 395 9.94E-19 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Spica_2590 29d4dfc0e42e8a4337c7358b8cc92a52 800 Gene3D G3DSA:3.40.50.1170 471 663 5.1E-27 T 13-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 Spica_0279 dc24b9ecb1c1f1a8b43cc088372cc20f 76 SUPERFAMILY SSF89447 4 67 3.45E-10 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Spica_0279 dc24b9ecb1c1f1a8b43cc088372cc20f 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 44 2.5E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Spica_0279 dc24b9ecb1c1f1a8b43cc088372cc20f 76 Gene3D G3DSA:2.10.260.10 1 76 3.5E-27 T 13-10-2018 Spica_0071 19df4dc86d1784f57c5e91073fd21cb8 514 Pfam PF03662 Glycosyl hydrolase family 79, N-terminal domain 57 346 5.1E-30 T 13-10-2018 IPR005199 Glycoside hydrolase, family 79 GO:0016020|GO:0016798 Reactome: R-HSA-2024096 Spica_0071 19df4dc86d1784f57c5e91073fd21cb8 514 SUPERFAMILY SSF51445 59 390 3.54E-41 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0071 19df4dc86d1784f57c5e91073fd21cb8 514 Gene3D G3DSA:3.20.20.80 52 388 1.5E-61 T 13-10-2018 Spica_2159 51b0e720f7ce33998d851da6e969fd9a 107 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 82 1.7E-9 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_2159 51b0e720f7ce33998d851da6e969fd9a 107 Gene3D G3DSA:3.30.2310.20 1 97 5.6E-22 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_2159 51b0e720f7ce33998d851da6e969fd9a 107 SUPERFAMILY SSF143011 1 83 2.35E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 SUPERFAMILY SSF117892 147 279 4.97E-28 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 SMART SM00244 115 273 2.0E-37 T 13-10-2018 IPR001107 Band 7 domain Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 Gene3D G3DSA:3.30.479.30 144 275 5.4E-35 T 13-10-2018 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 Pfam PF01145 SPFH domain / Band 7 family 120 289 1.1E-29 T 13-10-2018 IPR001107 Band 7 domain Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 205 222 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 268 289 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 293 316 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 170 191 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 249 267 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 122 144 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_2240 c8ccd62c870b5b394a56602efbc8c852 358 PRINTS PR00721 Stomatin signature 225 248 4.3E-37 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Spica_1100 b214190b95510e33be795700118c29c9 389 Gene3D G3DSA:3.90.230.10 142 388 2.9E-32 T 13-10-2018 Spica_1100 b214190b95510e33be795700118c29c9 389 Pfam PF00557 Metallopeptidase family M24 179 370 2.3E-23 T 13-10-2018 IPR000994 Peptidase M24 Spica_1100 b214190b95510e33be795700118c29c9 389 SUPERFAMILY SSF55920 141 373 4.32E-26 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Pfam PF00204 DNA gyrase B 221 390 1.2E-63 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 635 90.549 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 360 374 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 220 242 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 179 194 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 588 600 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 604 620 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 374 394 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 5 15 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 194 207 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 312 328 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR01159 DNA gyrase subunit B signature 470 479 2.0E-71 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 SMART SM00433 34 628 0.0 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 SUPERFAMILY SSF56719 394 626 2.88E-87 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 635 2.5E-304 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 172 3.5E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 SMART SM00387 30 174 3.9E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Gene3D G3DSA:3.40.50.670 398 635 1.2E-102 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 563 624 9.2E-30 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 SUPERFAMILY SSF55874 5 211 1.31E-72 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 SUPERFAMILY SSF54211 221 391 7.21E-60 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Pfam PF01751 Toprim domain 419 527 1.0E-17 T 13-10-2018 IPR006171 TOPRIM domain Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 268 281 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 69 82 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 486 502 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 34 49 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 112 126 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 504 521 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 420 434 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 567 583 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 PRINTS PR00418 DNA topoisomerase II family signature 524 536 8.0E-74 T 13-10-2018 Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Gene3D G3DSA:3.30.230.10 221 392 1.1E-72 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_2869 252f28816f83fa5e440e33c5e598a51c 635 Gene3D G3DSA:3.30.565.10 1 220 4.2E-90 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 Gene3D G3DSA:3.40.50.280 65 157 7.7E-6 T 13-10-2018 Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 SMART SM00729 183 383 1.0E-34 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 Pfam PF04055 Radical SAM superfamily 189 345 1.3E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 Pfam PF13311 Protein of unknown function (DUF4080) 374 447 9.7E-6 T 13-10-2018 IPR025288 Domain of unknown function DUF4080 Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 Gene3D G3DSA:3.80.30.20 181 388 3.7E-22 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 Pfam PF02310 B12 binding domain 18 145 5.5E-8 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Spica_0578 d55a02d7bf8204aea638aea437b936ed 554 SUPERFAMILY SSF102114 182 374 4.84E-43 T 13-10-2018 Spica_0036 4c9c2433d396ac8f449123959c297b47 507 Gene3D G3DSA:3.40.50.300 2 239 9.5E-54 T 13-10-2018 Spica_0036 4c9c2433d396ac8f449123959c297b47 507 SUPERFAMILY SSF52540 4 226 6.89E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0036 4c9c2433d396ac8f449123959c297b47 507 SMART SM00382 289 485 1.4E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0036 4c9c2433d396ac8f449123959c297b47 507 SMART SM00382 30 220 4.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0036 4c9c2433d396ac8f449123959c297b47 507 SUPERFAMILY SSF52540 248 497 1.38E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0036 4c9c2433d396ac8f449123959c297b47 507 Gene3D G3DSA:3.40.50.300 244 504 2.0E-44 T 13-10-2018 Spica_0036 4c9c2433d396ac8f449123959c297b47 507 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0036 4c9c2433d396ac8f449123959c297b47 507 Pfam PF00005 ABC transporter 281 436 8.9E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0036 4c9c2433d396ac8f449123959c297b47 507 Pfam PF00005 ABC transporter 21 172 4.4E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2584 97c362d820e90058e8dc4f425236d547 322 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 204 216 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Spica_2584 97c362d820e90058e8dc4f425236d547 322 Gene3D G3DSA:1.10.600.10 1 322 9.0E-89 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_2584 97c362d820e90058e8dc4f425236d547 322 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 96 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Spica_2584 97c362d820e90058e8dc4f425236d547 322 Pfam PF00348 Polyprenyl synthetase 32 261 9.7E-59 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Spica_2584 97c362d820e90058e8dc4f425236d547 322 SUPERFAMILY SSF48576 2 321 4.48E-75 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_2508 857482c43f78e08f2a5c2f3e6fe095cc 235 Pfam PF03692 Putative zinc- or iron-chelating domain 46 123 4.2E-8 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 75 1.0E-12 T 13-10-2018 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 4 142 6.1E-62 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 10 68 5.7E-29 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 1.1E-23 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 6 143 30.688 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 SUPERFAMILY SSF54747 3 86 2.75E-28 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 Gene3D G3DSA:3.30.1550.10 3 73 1.8E-30 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 SMART SM00649 10 142 2.1E-81 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 SUPERFAMILY SSF46906 69 142 1.7E-26 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Spica_0375 7795e16dc2b290bdee8f39c52bf4247f 143 Gene3D G3DSA:1.10.10.250 74 142 3.5E-28 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 SMART SM00938 4 105 3.9E-49 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 SUPERFAMILY SSF54913 1 112 1.49E-38 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 PRINTS PR00340 P-II protein signature 52 75 3.4E-28 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 PRINTS PR00340 P-II protein signature 23 41 3.4E-28 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 PRINTS PR00340 P-II protein signature 2 17 3.4E-28 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 PRINTS PR00340 P-II protein signature 83 103 3.4E-28 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 Gene3D G3DSA:3.30.70.120 1 112 1.2E-41 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_1647 5a7b9ec602de16bdc56af92278146c02 113 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.1E-34 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 Pfam PF01566 Natural resistance-associated macrophage protein 50 399 2.1E-125 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 13 425 36.532 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 315 334 7.3E-36 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 162 183 7.3E-36 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 212 235 7.3E-36 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 109 135 7.3E-36 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 137 156 7.3E-36 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2167 73bfeb7facba42fe936e01945573fa79 429 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 29 393 7.2E-112 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 SUPERFAMILY SSF53659 3 404 1.75E-113 T 13-10-2018 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 SMART SM01329 4 400 6.9E-187 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 Gene3D G3DSA:3.40.718.10 1 406 8.2E-137 T 13-10-2018 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 370 1.9E-119 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 367 3.5E-141 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Spica_2673 84e2918134f61f101097c8bf00b850fb 409 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 404 49.304 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 Gene3D G3DSA:2.30.42.10 111 205 3.2E-87 T 13-10-2018 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 SMART SM00228 111 190 2.0E-17 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 Gene3D G3DSA:3.30.750.44 56 355 3.2E-87 T 13-10-2018 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 SUPERFAMILY SSF52096 39 384 3.15E-69 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 SMART SM00245 191 380 3.1E-80 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 128 186 2.7E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 SUPERFAMILY SSF50156 82 221 1.45E-21 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 Gene3D G3DSA:3.90.226.10 206 377 3.2E-87 T 13-10-2018 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 65 390 4.3E-97 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 Spica_0239 f7e7e671656c7532dddf33f759b896c9 500 Pfam PF03572 Peptidase family S41 216 378 1.1E-51 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Spica_2094 79e39db43c3b2ea06b5e0c644ed740dd 310 Pfam PF01569 PAP2 superfamily 60 167 2.1E-20 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_2094 79e39db43c3b2ea06b5e0c644ed740dd 310 Gene3D G3DSA:1.20.144.10 87 186 2.4E-17 T 13-10-2018 Spica_2094 79e39db43c3b2ea06b5e0c644ed740dd 310 SMART SM00014 60 167 1.0E-14 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_2094 79e39db43c3b2ea06b5e0c644ed740dd 310 SUPERFAMILY SSF48317 8 165 1.96E-27 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily Spica_1862 c3553bbe598e799746e50266e07937bf 436 Pfam PF12833 Helix-turn-helix domain 352 429 2.9E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_1862 c3553bbe598e799746e50266e07937bf 436 Pfam PF00072 Response regulator receiver domain 5 116 2.0E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1862 c3553bbe598e799746e50266e07937bf 436 Gene3D G3DSA:1.10.10.60 378 433 4.3E-18 T 13-10-2018 Spica_1862 c3553bbe598e799746e50266e07937bf 436 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 412 428 1.1E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_1862 c3553bbe598e799746e50266e07937bf 436 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 397 412 1.1E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_1862 c3553bbe598e799746e50266e07937bf 436 Gene3D G3DSA:3.40.50.2300 1 138 4.7E-29 T 13-10-2018 Spica_1862 c3553bbe598e799746e50266e07937bf 436 SMART SM00342 345 428 1.0E-31 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_1862 c3553bbe598e799746e50266e07937bf 436 SMART SM00448 3 117 1.8E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1862 c3553bbe598e799746e50266e07937bf 436 SUPERFAMILY SSF46689 328 378 3.4E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1862 c3553bbe598e799746e50266e07937bf 436 SUPERFAMILY SSF52172 3 157 6.55E-31 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1862 c3553bbe598e799746e50266e07937bf 436 SUPERFAMILY SSF46689 381 431 1.29E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1862 c3553bbe598e799746e50266e07937bf 436 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 382 424 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_1862 c3553bbe598e799746e50266e07937bf 436 Gene3D G3DSA:1.10.10.60 330 377 8.9E-13 T 13-10-2018 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 117 261 3.8E-36 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 SUPERFAMILY SSF55347 116 223 4.36E-23 T 13-10-2018 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 SUPERFAMILY SSF51735 2 261 1.1E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0948 eda0e496ac5028591257a6bf2e855719 265 PIRSF PIRSF000161 1 263 6.6E-57 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 24.885 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 Gene3D G3DSA:3.30.360.10 115 221 1.5E-74 T 13-10-2018 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 54 239 8.4E-41 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 Gene3D G3DSA:3.40.50.720 2 239 1.5E-74 T 13-10-2018 Spica_0948 eda0e496ac5028591257a6bf2e855719 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 114 1.2E-14 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 480 35.169 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 478 1.8E-152 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 327 4.4E-103 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 SUPERFAMILY SSF47323 356 479 1.18E-27 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 SUPERFAMILY SSF52374 5 328 5.63E-87 T 13-10-2018 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 Gene3D G3DSA:3.40.50.620 1 319 2.0E-133 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 204 222 2.7E-23 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.7E-23 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 235 256 2.7E-23 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.7E-23 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Spica_0668 0e8403793bb4bcb979da9b43f6cf28b1 480 Gene3D G3DSA:1.20.120.1910 320 479 3.0E-35 T 13-10-2018 Spica_0118 5f25edd6215e9b622911dc9784add599 504 Pfam PF00464 Serine hydroxymethyltransferase 168 441 7.2E-93 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Spica_0118 5f25edd6215e9b622911dc9784add599 504 Pfam PF00464 Serine hydroxymethyltransferase 34 136 9.2E-29 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Spica_0118 5f25edd6215e9b622911dc9784add599 504 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 280 296 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Spica_0118 5f25edd6215e9b622911dc9784add599 504 SUPERFAMILY SSF53383 21 492 3.09E-144 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0118 5f25edd6215e9b622911dc9784add599 504 PIRSF PIRSF000412 8 495 7.5E-172 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Spica_0118 5f25edd6215e9b622911dc9784add599 504 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 31 490 43.856 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Spica_1762 c6f824d42769ea73015f6912340c2624 139 Pfam PF01850 PIN domain 5 122 1.4E-10 T 13-10-2018 IPR002716 PIN domain Spica_1762 c6f824d42769ea73015f6912340c2624 139 SUPERFAMILY SSF88723 1 130 7.29E-23 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1762 c6f824d42769ea73015f6912340c2624 139 Gene3D G3DSA:3.40.50.1010 4 138 3.8E-29 T 13-10-2018 Spica_1751 c6f824d42769ea73015f6912340c2624 139 Pfam PF01850 PIN domain 5 122 1.4E-10 T 13-10-2018 IPR002716 PIN domain Spica_1751 c6f824d42769ea73015f6912340c2624 139 SUPERFAMILY SSF88723 1 130 7.29E-23 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1751 c6f824d42769ea73015f6912340c2624 139 Gene3D G3DSA:3.40.50.1010 4 138 3.8E-29 T 13-10-2018 Spica_1779 c6f824d42769ea73015f6912340c2624 139 Pfam PF01850 PIN domain 5 122 1.4E-10 T 13-10-2018 IPR002716 PIN domain Spica_1779 c6f824d42769ea73015f6912340c2624 139 SUPERFAMILY SSF88723 1 130 7.29E-23 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1779 c6f824d42769ea73015f6912340c2624 139 Gene3D G3DSA:3.40.50.1010 4 138 3.8E-29 T 13-10-2018 Spica_0053 e712d0f7f3836435f52987a89b88c5aa 573 Pfam PF01095 Pectinesterase 210 474 4.4E-26 T 13-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 Spica_0053 e712d0f7f3836435f52987a89b88c5aa 573 SUPERFAMILY SSF51126 204 513 8.79E-39 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_0053 e712d0f7f3836435f52987a89b88c5aa 573 Gene3D G3DSA:2.160.20.10 206 528 6.8E-57 T 13-10-2018 IPR012334 Pectin lyase fold Spica_1309 a39521f9bab2458b482f512f947709b8 253 SUPERFAMILY SSF52540 4 233 5.99E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1309 a39521f9bab2458b482f512f947709b8 253 SMART SM00382 31 223 3.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1309 a39521f9bab2458b482f512f947709b8 253 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1309 a39521f9bab2458b482f512f947709b8 253 Gene3D G3DSA:3.40.50.300 7 246 1.1E-58 T 13-10-2018 Spica_1309 a39521f9bab2458b482f512f947709b8 253 Pfam PF00005 ABC transporter 22 167 3.1E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 SUPERFAMILY SSF52540 270 489 1.71E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 Gene3D G3DSA:3.40.50.300 243 497 5.4E-42 T 13-10-2018 Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 SUPERFAMILY SSF52540 5 230 1.25E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 Gene3D G3DSA:3.40.50.300 2 242 1.1E-55 T 13-10-2018 Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 Pfam PF00005 ABC transporter 21 172 5.4E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 SMART SM00382 281 476 4.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 SMART SM00382 30 228 2.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2149 72b4d1bb505c661fce548ebeb66c7b85 499 Pfam PF00005 ABC transporter 273 427 1.6E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1464 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_1464 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2187 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2187 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2524 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2524 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2447 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2447 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2082 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2082 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_1995 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_1995 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2449 adee596463959efe1db47abf6da3c944 487 Pfam PF05598 Transposase domain (DUF772) 53 123 1.9E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2449 adee596463959efe1db47abf6da3c944 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 Gene3D G3DSA:3.40.50.300 291 543 2.6E-56 T 13-10-2018 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 SUPERFAMILY SSF52540 6 246 4.43E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 Pfam PF12848 ABC transporter 233 315 1.8E-25 T 13-10-2018 IPR032781 ABC-transporter extension domain Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 Pfam PF00005 ABC transporter 345 474 6.5E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 Pfam PF00005 ABC transporter 19 193 8.5E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 SMART SM00382 28 253 1.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 SMART SM00382 352 519 5.0E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 Gene3D G3DSA:3.40.50.300 3 287 1.2E-63 T 13-10-2018 Spica_0750 3dd40f7d31bbc22479463e6c519b14cf 676 SUPERFAMILY SSF52540 306 529 7.76E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Pfam PF13407 Periplasmic binding protein domain 348 606 3.5E-44 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Pfam PF13407 Periplasmic binding protein domain 46 300 3.9E-40 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Gene3D G3DSA:3.40.50.2300 147 284 5.9E-79 T 13-10-2018 Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 SUPERFAMILY SSF53822 338 613 9.93E-65 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Gene3D G3DSA:3.40.50.2300 55 301 5.9E-79 T 13-10-2018 Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 SUPERFAMILY SSF53822 44 320 2.55E-58 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Gene3D G3DSA:3.40.50.2300 342 604 1.2E-92 T 13-10-2018 Spica_2215 57024bc6c52182dbb25834d6f04d1bfe 632 Gene3D G3DSA:3.40.50.2300 443 587 1.2E-92 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 SUPERFAMILY SSF52954 474 579 4.68E-29 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 SMART SM00863 105 162 5.1E-21 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 106 162 1.7E-11 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 269 473 1.8E-40 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 SUPERFAMILY SSF55681 186 471 3.45E-92 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Pfam PF03129 Anticodon binding domain 486 574 3.1E-22 T 13-10-2018 IPR004154 Anticodon-binding Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Gene3D G3DSA:3.30.980.10 8 165 2.1E-61 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 4 579 33.669 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Gene3D G3DSA:3.40.50.800 477 583 5.3E-30 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 10 574 3.7E-218 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Gene3D G3DSA:3.30.930.10 166 476 8.3E-123 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 PRINTS PR01047 Threonyl-tRNA synthetase signature 307 330 1.1E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 PRINTS PR01047 Threonyl-tRNA synthetase signature 452 465 1.1E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 PRINTS PR01047 Threonyl-tRNA synthetase signature 274 302 1.1E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 PRINTS PR01047 Threonyl-tRNA synthetase signature 409 437 1.1E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 PRINTS PR01047 Threonyl-tRNA synthetase signature 479 491 1.1E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 Gene3D G3DSA:3.30.54.20 68 128 2.1E-61 T 13-10-2018 Spica_2394 de746e5f099f2b48a2e257be7774f8f4 584 SUPERFAMILY SSF55186 3 184 1.83E-57 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 Gene3D G3DSA:3.40.50.300 2 237 3.0E-64 T 13-10-2018 Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 Pfam PF00005 ABC transporter 19 164 3.0E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 SUPERFAMILY SSF52540 3 235 1.97E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 SMART SM00382 28 216 1.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0417 1a832f55277a1b3ebb8d6175a50b5a67 237 PIRSF PIRSF039137 1 237 6.1E-110 T 13-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 487 31.906 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 SUPERFAMILY SSF52374 3 314 1.74E-112 T 13-10-2018 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 321 1.2E-103 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 485 8.7E-165 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 1.2E-25 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 1.2E-25 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 1.2E-25 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 1.2E-25 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 1.2E-25 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 Gene3D G3DSA:1.10.10.350 387 492 1.5E-22 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 Gene3D G3DSA:3.40.50.620 1 330 3.9E-147 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0891 fe4b039fe06ffaad587aef9c0af00c61 492 SUPERFAMILY SSF48163 315 488 1.31E-34 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 353 6.6E-162 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 SUPERFAMILY SSF75620 8 351 2.22E-134 T 13-10-2018 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Pfam PF00472 RF-1 domain 210 319 6.1E-42 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Gene3D G3DSA:1.20.58.410 4 99 7.4E-7 T 13-10-2018 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Gene3D G3DSA:3.30.70.1660 110 340 1.3E-99 T 13-10-2018 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.205 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Pfam PF03462 PCRF domain 10 202 4.4E-75 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 SMART SM00937 63 177 2.4E-61 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 Spica_0421 5789bba04c002c3712990b3cff288ca1 356 Gene3D G3DSA:3.30.160.20 209 295 1.3E-99 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Gene3D G3DSA:3.40.1160.10 1 297 2.4E-101 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1320 8b1c3cb130c62706c2958532241649bb 817 SUPERFAMILY SSF53633 1 296 6.41E-78 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Gene3D G3DSA:3.30.2130.10 301 460 4.3E-50 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Gene3D G3DSA:3.40.50.720 466 813 1.6E-116 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 SUPERFAMILY SSF55021 303 380 1.35E-19 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Pfam PF01842 ACT domain 405 457 3.8E-8 T 13-10-2018 IPR002912 ACT domain Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Pfam PF00742 Homoserine dehydrogenase 614 810 2.7E-49 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 SUPERFAMILY SSF55347 614 797 9.81E-45 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Pfam PF00696 Amino acid kinase family 2 283 9.7E-49 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Gene3D G3DSA:3.30.360.10 625 795 1.6E-116 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 459 9.2E-131 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 SUPERFAMILY SSF55021 387 462 5.44E-22 T 13-10-2018 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 SUPERFAMILY SSF51735 464 636 4.0E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1320 8b1c3cb130c62706c2958532241649bb 817 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 606 4.5E-13 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Spica_1320 8b1c3cb130c62706c2958532241649bb 817 PIRSF PIRSF000727 1 817 1.2E-273 T 13-10-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_1643 cb4967df3073aa6811efb4cef0ff0e7d 270 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 267 1.1E-68 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 Spica_1643 cb4967df3073aa6811efb4cef0ff0e7d 270 SUPERFAMILY SSF51556 1 267 2.14E-63 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_1643 cb4967df3073aa6811efb4cef0ff0e7d 270 PIRSF PIRSF005902 1 270 2.3E-67 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_1643 cb4967df3073aa6811efb4cef0ff0e7d 270 Gene3D G3DSA:3.20.20.140 1 269 8.1E-73 T 13-10-2018 Spica_1643 cb4967df3073aa6811efb4cef0ff0e7d 270 Pfam PF01026 TatD related DNase 5 267 1.1E-58 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 577 37.912 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Gene3D G3DSA:1.10.220.120 5 65 1.8E-12 T 13-10-2018 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Pfam PF03979 Sigma-70 factor, region 1.1 8 75 4.7E-14 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 SUPERFAMILY SSF88946 91 414 9.68E-56 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Pfam PF00140 Sigma-70 factor, region 1.2 92 123 2.9E-14 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Pfam PF04539 Sigma-70 region 3 423 499 9.1E-28 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 340 565 2.1E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Gene3D G3DSA:1.10.10.10 417 493 1.5E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 340 576 6.6E-122 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 SUPERFAMILY SSF88659 474 577 1.23E-28 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 SUPERFAMILY SSF88659 417 490 1.28E-20 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 537 563 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Gene3D G3DSA:1.10.10.10 494 578 1.2E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 PRINTS PR00046 Major sigma-70 factor signature 368 381 3.5E-29 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 PRINTS PR00046 Major sigma-70 factor signature 392 400 3.5E-29 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 PRINTS PR00046 Major sigma-70 factor signature 516 528 3.5E-29 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 PRINTS PR00046 Major sigma-70 factor signature 537 552 3.5E-29 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 PRINTS PR00046 Major sigma-70 factor signature 552 563 3.5E-29 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Gene3D G3DSA:1.10.601.10 90 416 6.8E-81 T 13-10-2018 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Pfam PF04545 Sigma-70, region 4 512 565 3.1E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 368 381 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1392 ccd0b3a1826e7716f9c37c5d32e4b627 578 Pfam PF04542 Sigma-70 region 2 344 413 5.0E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_2000 842caf9c6516eaa3170a9f721faf53df 433 Pfam PF12704 MacB-like periplasmic core domain 15 225 2.3E-13 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Spica_2000 842caf9c6516eaa3170a9f721faf53df 433 Pfam PF02687 FtsX-like permease family 327 422 4.4E-6 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_0107 a2735ab7f922a3e1a481214a0021b1a7 458 Pfam PF13635 Domain of unknown function (DUF4143) 244 390 4.7E-17 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_0107 a2735ab7f922a3e1a481214a0021b1a7 458 SUPERFAMILY SSF52540 5 204 1.02E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0107 a2735ab7f922a3e1a481214a0021b1a7 458 SMART SM00382 17 137 6.1E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0107 a2735ab7f922a3e1a481214a0021b1a7 458 Pfam PF13173 AAA domain 17 152 7.7E-24 T 13-10-2018 Spica_0107 a2735ab7f922a3e1a481214a0021b1a7 458 Gene3D G3DSA:3.40.50.300 9 150 6.4E-9 T 13-10-2018 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Gene3D G3DSA:1.50.10.10 334 749 0.0 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Gene3D G3DSA:2.60.420.10 327 807 0.0 T 13-10-2018 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 SMART SM01068 1 63 4.1E-17 T 13-10-2018 IPR009342 Putative carbohydrate binding domain Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Gene3D G3DSA:2.70.98.40 2 714 0.0 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Pfam PF06165 Glycosyltransferase family 36 21 275 5.0E-82 T 13-10-2018 IPR010383 Glycosyl hydrolase 94 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 SUPERFAMILY SSF48208 298 787 1.36E-90 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Gene3D G3DSA:1.20.890.20 279 326 0.0 T 13-10-2018 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 SUPERFAMILY SSF74650 1 276 6.91E-73 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0356 e5c72bdccce6f8f7602eecd0d6b89a38 821 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 319 749 2.4E-164 T 13-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 ProSitePatterns PS00321 recA signature. 230 238 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 110 139 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 315 332 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 144 173 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 182 211 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 227 255 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 PRINTS PR00142 RecA protein signature 261 290 7.6E-82 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 Gene3D G3DSA:3.40.50.300 46 285 1.4E-80 T 13-10-2018 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 SMART SM00382 74 245 1.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 Pfam PF00154 recA bacterial DNA recombination protein 23 286 1.6E-140 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 20 341 5.8E-167 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 SUPERFAMILY SSF54752 288 342 5.23E-19 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 Gene3D G3DSA:3.30.250.10 286 360 7.1E-24 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 Hamap MF_00268 Protein RecA [recA]. 21 347 51.948 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Spica_1373 8e4c27e25984cb186527ad8b315e9670 431 SUPERFAMILY SSF52540 20 285 1.97E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 378 400 1.4E-9 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 155 164 1.4E-9 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 71 88 1.4E-9 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01181 Diaminopimelate decarboxylase signature 296 314 1.4E-9 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0951 193ce152db85d8d6707c7793e2984691 425 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_0951 193ce152db85d8d6707c7793e2984691 425 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 24 368 7.0E-19 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 269 288 5.8E-8 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 5.8E-8 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 5.8E-8 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 368 381 5.8E-8 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 SUPERFAMILY SSF50621 254 409 1.21E-40 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 Gene3D G3DSA:2.40.37.10 13 409 7.1E-102 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 SUPERFAMILY SSF51419 21 280 1.34E-55 T 13-10-2018 IPR029066 PLP-binding barrel Spica_0951 193ce152db85d8d6707c7793e2984691 425 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 31 278 1.5E-22 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Spica_0951 193ce152db85d8d6707c7793e2984691 425 Gene3D G3DSA:3.20.20.10 29 274 7.1E-102 T 13-10-2018 IPR029066 PLP-binding barrel Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 SMART SM00490 257 338 3.0E-29 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 ProSitePatterns PS00018 EF-hand calcium-binding domain. 134 146 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 SMART SM00487 20 221 8.4E-56 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 SUPERFAMILY SSF52540 71 360 1.12E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 Pfam PF00271 Helicase conserved C-terminal domain 229 338 5.5E-28 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 Gene3D G3DSA:3.40.50.300 211 378 1.5E-47 T 13-10-2018 Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 Pfam PF00270 DEAD/DEAH box helicase 25 194 8.3E-46 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_0572 c60a5a32a35d34d28f76a8407e52e498 566 Gene3D G3DSA:3.40.50.300 1 209 7.6E-68 T 13-10-2018 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 179 1.5E-52 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 Pfam PF01386 Ribosomal L25p family 6 92 8.3E-22 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 95 3.0E-15 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 Gene3D G3DSA:2.170.120.20 96 189 1.4E-28 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 180 1.3E-27 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 183 27.83 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 Gene3D G3DSA:2.40.240.10 4 95 7.3E-24 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0792 d21c6acde9eb4338618285d17fe74eb1 210 SUPERFAMILY SSF50715 4 189 1.17E-52 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_2814 486f0f6c5a62230c6333956004395112 517 SMART SM00382 30 228 3.5E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2814 486f0f6c5a62230c6333956004395112 517 SMART SM00382 289 492 0.0012 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2814 486f0f6c5a62230c6333956004395112 517 Gene3D G3DSA:3.40.50.300 2 243 1.6E-54 T 13-10-2018 Spica_2814 486f0f6c5a62230c6333956004395112 517 Gene3D G3DSA:3.40.50.300 249 516 5.0E-43 T 13-10-2018 Spica_2814 486f0f6c5a62230c6333956004395112 517 Pfam PF00005 ABC transporter 21 172 1.6E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2814 486f0f6c5a62230c6333956004395112 517 SUPERFAMILY SSF52540 245 494 1.04E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2814 486f0f6c5a62230c6333956004395112 517 Pfam PF00005 ABC transporter 280 436 3.0E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2814 486f0f6c5a62230c6333956004395112 517 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2814 486f0f6c5a62230c6333956004395112 517 SUPERFAMILY SSF52540 4 225 1.13E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 Gene3D G3DSA:3.20.130.10 393 576 9.5E-51 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 Pfam PF05683 Fumarase C-terminus 366 576 2.9E-68 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 PIRSF PIRSF001394 366 584 1.1E-64 T 13-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 PIRSF PIRSF001394 25 391 1.1E-84 T 13-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 414 576 4.8E-44 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 Pfam PF05681 Fumarate hydratase (Fumerase) 42 327 1.1E-72 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 Spica_1190 8c0312b8494cf1cf827b6000722cad1f 588 SUPERFAMILY SSF117457 408 575 1.83E-49 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 SUPERFAMILY SSF50249 65 129 2.87E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0966 60b623538988d1bd069fb9da44997dc0 187 PIRSF PIRSF005901 1 186 3.6E-65 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP Spica_0966 60b623538988d1bd069fb9da44997dc0 187 SMART SM01185 67 121 1.1E-20 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 3.8E-19 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Gene3D G3DSA:2.40.50.140 64 127 4.9E-20 T 13-10-2018 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 TIGRFAM TIGR00038 efp: translation elongation factor P 4 185 1.7E-66 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Gene3D G3DSA:2.40.50.140 129 185 3.8E-23 T 13-10-2018 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 54 1.6E-15 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like Spica_0966 60b623538988d1bd069fb9da44997dc0 187 SMART SM00841 129 184 1.9E-26 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 SUPERFAMILY SSF50249 129 185 5.14E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Gene3D G3DSA:2.30.30.30 1 62 1.4E-15 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 44.299 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Spica_0966 60b623538988d1bd069fb9da44997dc0 187 SUPERFAMILY SSF50104 1 61 9.63E-14 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_0966 60b623538988d1bd069fb9da44997dc0 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 3.9E-23 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 332 346 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 410 432 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 522 538 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 547 563 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 468 483 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 243 258 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 360 375 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PRINTS PR00743 Glycosyl hydrolase family 36 signature 294 314 6.9E-58 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Pfam PF02065 Melibiase 292 637 2.2E-151 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 286 9.8E-82 T 13-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Gene3D G3DSA:2.60.40.1180 669 776 1.1E-17 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PIRSF PIRSF005536 662 775 8.1E-7 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 PIRSF PIRSF005536 1 647 9.5E-251 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 ProSitePatterns PS00512 Alpha-galactosidase signature. 361 380 - T 13-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 678 774 1.8E-19 T 13-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Gene3D G3DSA:2.70.98.60 1 310 4.5E-103 T 13-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 Gene3D G3DSA:3.20.20.70 312 634 6.4E-126 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0299 411f5d7b4bd041d67cbfd474796fae86 776 SUPERFAMILY SSF51445 326 642 3.79E-103 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1670 f83512420ea7860c074b0743be29ef9a 568 Pfam PF01514 Secretory protein of YscJ/FliF family 31 224 1.4E-44 T 13-10-2018 IPR006182 Secretory protein YscJ/FliF Spica_1670 f83512420ea7860c074b0743be29ef9a 568 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 567 8.4E-115 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Spica_1670 f83512420ea7860c074b0743be29ef9a 568 Pfam PF08345 Flagellar M-ring protein C-terminal 260 450 1.1E-25 T 13-10-2018 IPR013556 Flagellar M-ring C-terminal Spica_1670 f83512420ea7860c074b0743be29ef9a 568 Gene3D G3DSA:3.30.300.30 124 222 1.1E-8 T 13-10-2018 Spica_1670 f83512420ea7860c074b0743be29ef9a 568 PRINTS PR01009 Flagellar M-ring protein signature 200 218 1.5E-9 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Spica_1670 f83512420ea7860c074b0743be29ef9a 568 PRINTS PR01009 Flagellar M-ring protein signature 274 292 1.5E-9 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Spica_1670 f83512420ea7860c074b0743be29ef9a 568 PRINTS PR01009 Flagellar M-ring protein signature 155 169 1.5E-9 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Spica_1670 f83512420ea7860c074b0743be29ef9a 568 PRINTS PR01009 Flagellar M-ring protein signature 123 141 1.5E-9 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Spica_1811 97904673ca2695965970b927fa772364 261 Pfam PF00226 DnaJ domain 3 63 3.5E-17 T 13-10-2018 IPR001623 DnaJ domain Spica_1811 97904673ca2695965970b927fa772364 261 PRINTS PR00625 DnaJ domain signature 23 38 3.0E-6 T 13-10-2018 IPR001623 DnaJ domain Spica_1811 97904673ca2695965970b927fa772364 261 PRINTS PR00625 DnaJ domain signature 5 23 3.0E-6 T 13-10-2018 IPR001623 DnaJ domain Spica_1811 97904673ca2695965970b927fa772364 261 Gene3D G3DSA:1.10.287.110 1 80 7.9E-19 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_1811 97904673ca2695965970b927fa772364 261 SUPERFAMILY SSF46565 3 70 6.15E-20 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_1811 97904673ca2695965970b927fa772364 261 SMART SM00271 2 58 4.0E-17 T 13-10-2018 IPR001623 DnaJ domain Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 SUPERFAMILY SSF140990 457 649 7.46E-66 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 SMART SM00382 238 377 8.6E-23 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Pfam PF01434 Peptidase family M41 436 647 1.6E-74 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Gene3D G3DSA:3.40.50.300 195 375 1.1E-65 T 13-10-2018 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 SUPERFAMILY SSF52540 204 445 1.19E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Gene3D G3DSA:1.20.58.760 456 655 2.4E-70 T 13-10-2018 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 153 648 2.3E-222 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 45 656 36.213 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Pfam PF06480 FtsH Extracellular 49 146 1.1E-5 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Gene3D G3DSA:1.10.8.60 376 453 1.8E-29 T 13-10-2018 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 ProSitePatterns PS00674 AAA-protein family signature. 345 363 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Spica_0457 93ab6da89f20dbcc482835dfdcdd0547 656 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 242 374 1.1E-43 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 203 1.3E-24 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 Gene3D G3DSA:3.40.47.10 1 344 1.1E-120 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 344 63.259 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 344 2.1E-102 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 255 344 7.5E-34 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Spica_2035 64735fb02dc73f13aa86b66162c6418f 344 SUPERFAMILY SSF53901 3 344 5.62E-55 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 271 1.5E-36 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Gene3D G3DSA:1.10.10.10 123 198 7.3E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 74 87 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 SUPERFAMILY SSF88659 123 196 3.4E-14 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PIRSF PIRSF000770 4 278 6.4E-36 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Pfam PF04539 Sigma-70 region 3 129 201 1.3E-17 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Pfam PF04545 Sigma-70, region 4 218 270 4.0E-17 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Gene3D G3DSA:1.10.601.10 4 119 9.2E-41 T 13-10-2018 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Pfam PF04542 Sigma-70 region 2 50 119 5.4E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 242 268 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 SUPERFAMILY SSF88659 182 272 8.22E-20 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Pfam PF00140 Sigma-70 factor, region 1.2 12 44 9.8E-11 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 Gene3D G3DSA:1.10.10.10 199 280 3.7E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 SUPERFAMILY SSF88946 11 120 9.68E-41 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PRINTS PR00046 Major sigma-70 factor signature 74 87 4.2E-23 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PRINTS PR00046 Major sigma-70 factor signature 98 106 4.2E-23 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PRINTS PR00046 Major sigma-70 factor signature 257 268 4.2E-23 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PRINTS PR00046 Major sigma-70 factor signature 221 233 4.2E-23 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0849 177311d48bf695587739c4c07a9dc0d8 281 PRINTS PR00046 Major sigma-70 factor signature 242 257 4.2E-23 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 420 449 1.4E-24 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 23 48 1.4E-24 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 343 370 1.4E-24 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 372 401 1.4E-24 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 SUPERFAMILY SSF58104 262 492 2.49E-46 T 13-10-2018 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 168 514 0.002 T 13-10-2018 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 SMART SM00283 245 492 2.3E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 Gene3D G3DSA:1.10.287.950 192 492 2.7E-51 T 13-10-2018 Spica_1945 be4f02393c6e24fea122e49b1060fb64 534 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 311 458 3.8E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 SUPERFAMILY SSF50443 371 604 8.11E-121 T 13-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Hamap MF_01254 L-fucose isomerase [fucI]. 17 605 67.73 T 13-10-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Pfam PF07882 L-fucose isomerase, second N-terminal domain 190 369 4.5E-91 T 13-10-2018 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 TIGRFAM TIGR01089 fucI: L-fucose isomerase 20 603 0.0 T 13-10-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Gene3D G3DSA:3.40.50.1070 11 190 2.6E-90 T 13-10-2018 IPR038391 L-fucose isomerase, domain 1 superfamily KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Gene3D G3DSA:3.40.275.10 191 355 2.0E-77 T 13-10-2018 IPR038392 L-fucose isomerase, domain 2 superfamily KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Pfam PF07881 L-fucose isomerase, first N-terminal domain 21 189 1.8E-82 T 13-10-2018 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Pfam PF02952 L-fucose isomerase, C-terminal domain 405 568 9.4E-49 T 13-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 Gene3D G3DSA:3.20.14.10 356 605 1.2E-124 T 13-10-2018 IPR038393 L-fucose isomerase, domain 3 superfamily KEGG: 00051+5.3.1.25 Spica_2242 776df82fd84f261f46bd668fbe225d10 606 SUPERFAMILY SSF53743 19 370 3.01E-144 T 13-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PIRSF PIRSF001529 1 425 4.9E-149 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 Gene3D G3DSA:1.10.287.40 1 103 4.1E-22 T 13-10-2018 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 Gene3D G3DSA:3.30.930.10 104 425 1.6E-131 T 13-10-2018 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PRINTS PR00981 Seryl-tRNA synthetase signature 274 287 3.5E-26 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PRINTS PR00981 Seryl-tRNA synthetase signature 314 327 3.5E-26 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PRINTS PR00981 Seryl-tRNA synthetase signature 262 274 3.5E-26 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PRINTS PR00981 Seryl-tRNA synthetase signature 331 347 3.5E-26 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 3.5E-26 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 415 3.4E-150 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 SUPERFAMILY SSF46589 1 111 6.28E-22 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 SUPERFAMILY SSF55681 116 421 1.19E-86 T 13-10-2018 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 226 398 1.7E-28 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 38.372 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Spica_0561 b76962aadaa2e0f84e514d23fdc50f9c 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 105 6.8E-21 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 Gene3D G3DSA:3.40.50.12740 4 224 7.5E-65 T 13-10-2018 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 9.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 9.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 9.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 SUPERFAMILY SSF52172 1 197 1.42E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 SMART SM00448 4 123 1.0E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 SMART SM00421 163 220 8.3E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 2.6E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0150 4f2c4ea72c51d90288f74c79cd46ea91 227 Pfam PF00072 Response regulator receiver domain 6 124 1.1E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1851 afbbbaf5e193affb578293f3e1570c30 594 SMART SM00331 202 428 1.3E-30 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1851 afbbbaf5e193affb578293f3e1570c30 594 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 230 427 3.9E-34 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1851 afbbbaf5e193affb578293f3e1570c30 594 SUPERFAMILY SSF81606 218 428 6.41E-8 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1851 afbbbaf5e193affb578293f3e1570c30 594 Gene3D G3DSA:3.60.40.10 172 427 3.5E-47 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2544 ec7e42315adc01b355bdb4b4596506c5 180 Gene3D G3DSA:3.40.109.10 2 179 6.1E-46 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_2544 ec7e42315adc01b355bdb4b4596506c5 180 SUPERFAMILY SSF55469 3 180 7.59E-42 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_2544 ec7e42315adc01b355bdb4b4596506c5 180 Pfam PF00881 Nitroreductase family 6 147 1.0E-22 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 SUPERFAMILY SSF46785 9 94 4.3E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 50 2.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 2.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.1E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 SMART SM00418 17 96 1.3E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 Pfam PF01022 Bacterial regulatory protein, arsR family 24 71 4.4E-9 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_1319 7253a00cb9a4cfed8403c80ae7470492 100 Gene3D G3DSA:1.10.10.10 2 99 4.5E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2282 d77cf8b718fe5195127054b5f151c3f3 106 SUPERFAMILY SSF102705 3 102 1.26E-19 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Spica_2282 d77cf8b718fe5195127054b5f151c3f3 106 Gene3D G3DSA:3.30.70.120 1 104 4.6E-35 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SUPERFAMILY SSF48452 205 316 2.68E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Gene3D G3DSA:1.25.40.10 235 329 9.1E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Pfam PF13424 Tetratricopeptide repeat 137 199 5.5E-8 T 13-10-2018 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SMART SM00028 135 168 4.2E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SMART SM00028 62 95 1.4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SMART SM00028 237 270 22.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SMART SM00028 169 202 4.6E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SMART SM00028 275 308 12.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Gene3D G3DSA:1.25.40.10 45 123 3.9E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Pfam PF04471 Restriction endonuclease 382 444 8.4E-7 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Gene3D G3DSA:1.25.40.10 124 234 1.2E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Pfam PF13174 Tetratricopeptide repeat 205 227 0.0046 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 Pfam PF13174 Tetratricopeptide repeat 63 90 0.047 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0364 5695bc4862e80e89412c5c3dfe1d2560 459 SUPERFAMILY SSF48452 52 228 3.03E-30 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 SUPERFAMILY SSF53067 117 343 1.3E-52 T 13-10-2018 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 Gene3D G3DSA:3.30.420.40 137 332 2.7E-148 T 13-10-2018 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 351 1.7E-154 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 Pfam PF00871 Acetokinase family 5 330 2.1E-67 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 PIRSF PIRSF036458 1 355 1.2E-152 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 SUPERFAMILY SSF53067 3 171 2.2E-65 T 13-10-2018 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 Gene3D G3DSA:3.30.420.40 5 355 2.7E-148 T 13-10-2018 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 PRINTS PR00471 Acetate kinase family signature 5 16 1.6E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 PRINTS PR00471 Acetate kinase family signature 274 287 1.6E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 PRINTS PR00471 Acetate kinase family signature 297 313 1.6E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 PRINTS PR00471 Acetate kinase family signature 179 200 1.6E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2640 639cdc95d4d0f14273f3f680113619f2 355 Hamap MF_00542 Probable butyrate kinase [buk]. 1 355 149.951 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 Spica_1475 c5c82ebede99f949f0f51db64dfd730d 307 SUPERFAMILY SSF103481 206 303 4.45E-10 T 13-10-2018 Spica_1475 c5c82ebede99f949f0f51db64dfd730d 307 Pfam PF00892 EamA-like transporter family 18 146 5.8E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_1475 c5c82ebede99f949f0f51db64dfd730d 307 Pfam PF00892 EamA-like transporter family 168 298 9.1E-11 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_1475 c5c82ebede99f949f0f51db64dfd730d 307 SUPERFAMILY SSF103481 51 148 2.35E-16 T 13-10-2018 Spica_2803 83342c840c942e6b31685d1d2607739c 483 Pfam PF03949 Malic enzyme, NAD binding domain 195 418 6.2E-25 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Spica_2803 83342c840c942e6b31685d1d2607739c 483 PIRSF PIRSF000106 7 454 5.8E-96 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 Spica_2803 83342c840c942e6b31685d1d2607739c 483 SMART SM01274 43 182 2.9E-53 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spica_2803 83342c840c942e6b31685d1d2607739c 483 Gene3D G3DSA:3.40.50.10380 1 191 1.0E-66 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 Spica_2803 83342c840c942e6b31685d1d2607739c 483 Gene3D G3DSA:3.40.50.720 192 483 4.8E-103 T 13-10-2018 Spica_2803 83342c840c942e6b31685d1d2607739c 483 SUPERFAMILY SSF51735 195 456 1.88E-67 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2803 83342c840c942e6b31685d1d2607739c 483 SMART SM00919 194 425 2.2E-95 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Spica_2803 83342c840c942e6b31685d1d2607739c 483 SUPERFAMILY SSF53223 39 192 2.66E-42 T 13-10-2018 Spica_2803 83342c840c942e6b31685d1d2607739c 483 Pfam PF00390 Malic enzyme, N-terminal domain 61 182 2.7E-16 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Spica_2028 928577266c2816334a110ce07a736bcc 165 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 99 116 - T 13-10-2018 IPR000614 Free Met sulfoxide reductase conserved site Spica_2028 928577266c2816334a110ce07a736bcc 165 SUPERFAMILY SSF55781 15 160 3.68E-30 T 13-10-2018 Spica_2028 928577266c2816334a110ce07a736bcc 165 Pfam PF13185 GAF domain 59 155 1.6E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2028 928577266c2816334a110ce07a736bcc 165 Gene3D G3DSA:3.30.450.40 10 163 1.3E-48 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 Pfam PF00072 Response regulator receiver domain 6 118 8.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 Gene3D G3DSA:1.10.10.60 307 356 1.2E-11 T 13-10-2018 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 Gene3D G3DSA:1.10.10.60 357 412 2.6E-17 T 13-10-2018 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 SMART SM00448 4 118 2.1E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 361 403 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 SUPERFAMILY SSF46689 309 355 1.61E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 Pfam PF12833 Helix-turn-helix domain 331 409 1.5E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 SUPERFAMILY SSF46689 361 410 1.03E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 SMART SM00342 324 407 3.0E-27 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 SUPERFAMILY SSF52172 1 148 4.41E-33 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 376 391 4.3E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 391 407 4.3E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2631 31f6ba54934568c8e8ae0596ce454186 413 Gene3D G3DSA:3.40.50.2300 1 139 2.2E-33 T 13-10-2018 Spica_1530 bb473ea2062bcb54efb05d2d0bccab90 200 Pfam PF04347 Flagellar biosynthesis protein, FliO 88 168 2.0E-10 T 13-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 Spica_0582 2750c81340b1db177544bc99a8eca637 197 SUPERFAMILY SSF48498 85 179 3.78E-7 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_0582 2750c81340b1db177544bc99a8eca637 197 Gene3D G3DSA:1.10.357.10 5 196 3.3E-30 T 13-10-2018 Spica_0582 2750c81340b1db177544bc99a8eca637 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 6.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0582 2750c81340b1db177544bc99a8eca637 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 6.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0582 2750c81340b1db177544bc99a8eca637 197 SUPERFAMILY SSF46689 7 72 1.15E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0582 2750c81340b1db177544bc99a8eca637 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.5E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2836 e33c8ef7ee60071ce54faacefaa33f94 208 Gene3D G3DSA:1.10.40.40 19 72 8.5E-32 T 13-10-2018 Spica_2836 e33c8ef7ee60071ce54faacefaa33f94 208 Gene3D G3DSA:3.40.50.1000 10 184 8.5E-32 T 13-10-2018 IPR023214 HAD superfamily Spica_2836 e33c8ef7ee60071ce54faacefaa33f94 208 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 7 189 3.1E-47 T 13-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 Spica_2836 e33c8ef7ee60071ce54faacefaa33f94 208 SUPERFAMILY SSF56784 8 188 1.19E-30 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 103 1.9E-23 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 SUPERFAMILY SSF46548 137 241 1.01E-15 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 SUPERFAMILY SSF54292 5 100 3.15E-23 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 Pfam PF13183 4Fe-4S dicluster domain 147 225 1.8E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 6 237 5.0E-43 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 Gene3D G3DSA:3.10.20.30 1 100 4.4E-25 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_0338 616f0d8527be916cd6dafa7734b7489d 246 Gene3D G3DSA:1.10.1060.10 123 246 2.7E-24 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_1710 08a66ce9c117aeca3887f2d6e726a8cf 335 Gene3D G3DSA:3.40.50.970 1 329 8.9E-124 T 13-10-2018 Spica_1710 08a66ce9c117aeca3887f2d6e726a8cf 335 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 6 319 1.1E-135 T 13-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 Spica_1710 08a66ce9c117aeca3887f2d6e726a8cf 335 SUPERFAMILY SSF52518 2 322 5.89E-104 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1710 08a66ce9c117aeca3887f2d6e726a8cf 335 Pfam PF00676 Dehydrogenase E1 component 14 309 6.4E-92 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Spica_1860 374e9acb2c213c36907f760ec8c11396 331 SUPERFAMILY SSF53822 51 313 6.06E-31 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1860 374e9acb2c213c36907f760ec8c11396 331 Pfam PF13407 Periplasmic binding protein domain 53 308 4.9E-29 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_1860 374e9acb2c213c36907f760ec8c11396 331 Gene3D G3DSA:3.40.50.2300 61 300 1.7E-34 T 13-10-2018 Spica_1860 374e9acb2c213c36907f760ec8c11396 331 Gene3D G3DSA:3.40.50.2300 154 292 1.7E-34 T 13-10-2018 Spica_0643 8e456941f638737034224bd00cf6a27e 154 Gene3D G3DSA:2.30.110.10 1 152 5.3E-41 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Spica_0643 8e456941f638737034224bd00cf6a27e 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 149 4.5E-24 T 13-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related Spica_0643 8e456941f638737034224bd00cf6a27e 154 SUPERFAMILY SSF50475 1 151 2.75E-42 T 13-10-2018 Spica_0232 26dcf5f2bab961cb0c61e05428b52c20 183 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 24 125 3.5E-17 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spica_0232 26dcf5f2bab961cb0c61e05428b52c20 183 Pfam PF01740 STAS domain 25 125 7.9E-19 T 13-10-2018 IPR002645 STAS domain Spica_0232 26dcf5f2bab961cb0c61e05428b52c20 183 SUPERFAMILY SSF52091 25 130 6.28E-22 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0232 26dcf5f2bab961cb0c61e05428b52c20 183 Gene3D G3DSA:3.30.750.24 19 126 7.6E-22 T 13-10-2018 IPR036513 STAS domain superfamily Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 Pfam PF04204 Homoserine O-succinyltransferase 2 298 2.8E-131 T 13-10-2018 IPR033752 MetA family Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 SUPERFAMILY SSF52317 17 296 8.46E-101 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 Gene3D G3DSA:3.40.50.880 1 300 8.9E-126 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 8.8E-129 T 13-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 PIRSF PIRSF000450 1 304 3.1E-143 T 13-10-2018 IPR033752 MetA family Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 298 41.869 T 13-10-2018 IPR033752 MetA family Spica_1476 a7db2734c4c08548dfae5442e6e89d1a 304 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-76 T 13-10-2018 Spica_2319 035ea1e07d0524e32c798d90f25e5ba4 341 Gene3D G3DSA:3.40.50.2300 50 296 9.6E-54 T 13-10-2018 Spica_2319 035ea1e07d0524e32c798d90f25e5ba4 341 SUPERFAMILY SSF53822 49 307 1.01E-45 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2319 035ea1e07d0524e32c798d90f25e5ba4 341 Gene3D G3DSA:3.40.50.2300 143 283 9.6E-54 T 13-10-2018 Spica_2319 035ea1e07d0524e32c798d90f25e5ba4 341 Pfam PF13407 Periplasmic binding protein domain 50 301 1.2E-33 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0278 6a42817d907ae56183f01d1d88712cad 81 Gene3D G3DSA:1.10.1220.10 5 49 4.0E-5 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Spica_0278 6a42817d907ae56183f01d1d88712cad 81 SUPERFAMILY SSF47598 4 61 7.78E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 Gene3D G3DSA:3.30.565.10 285 434 3.5E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 SUPERFAMILY SSF55874 289 433 1.57E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 SMART SM00387 324 434 2.0E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 Gene3D G3DSA:1.10.287.130 183 279 1.2E-11 T 13-10-2018 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 SMART SM00388 217 281 3.9E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 433 8.6E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 280 4.2E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 SUPERFAMILY SSF47384 217 280 4.51E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 3.5E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 3.5E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0185 a868fbdc341d32d66d1e5342e74ec8f6 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 3.5E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 Gene3D G3DSA:3.40.50.720 6 360 3.5E-137 T 13-10-2018 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 SUPERFAMILY SSF55347 162 347 1.04E-35 T 13-10-2018 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 173 345 1.5E-36 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 SMART SM00859 5 142 1.2E-26 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 Gene3D G3DSA:3.30.360.10 163 342 3.5E-137 T 13-10-2018 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 244 258 - T 13-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 SUPERFAMILY SSF51735 4 187 3.88E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 360 1.2E-113 T 13-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 139 2.3E-25 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spica_0950 f0730b544e3fc1766ff642b1807607cc 365 PIRSF PIRSF000148 3 365 1.1E-97 T 13-10-2018 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 Gene3D G3DSA:2.40.50.140 11 90 3.5E-31 T 13-10-2018 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 12 82 2.3E-32 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 Pfam PF00366 Ribosomal protein S17 17 83 2.5E-28 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 SUPERFAMILY SSF50249 12 89 3.04E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 12 82 2.0E-19 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 12 87 23.288 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 ProSitePatterns PS00056 Ribosomal protein S17 signature. 63 75 - T 13-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 PRINTS PR00973 Ribosomal protein S17 family signature 63 73 1.9E-10 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 PRINTS PR00973 Ribosomal protein S17 family signature 73 80 1.9E-10 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0394 d9cc22ee9a8cf61d54ab9513c4ff07ee 90 PRINTS PR00973 Ribosomal protein S17 family signature 31 54 1.9E-10 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 Pfam PF08402 TOBE domain 284 355 2.5E-7 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 Gene3D G3DSA:2.40.50.100 240 360 1.9E-25 T 13-10-2018 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 Gene3D G3DSA:2.40.50.140 286 348 1.9E-25 T 13-10-2018 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 SMART SM00382 29 212 7.5E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 SUPERFAMILY SSF50331 237 363 4.37E-27 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 SUPERFAMILY SSF52540 4 244 1.41E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 Gene3D G3DSA:3.40.50.300 1 239 7.4E-74 T 13-10-2018 Spica_0943 cedd55084a28df3bc30c32bd874ddb97 375 Pfam PF00005 ABC transporter 21 162 5.9E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2437 f521eca0e551a45f70b6a394bafde712 392 Pfam PF00155 Aminotransferase class I and II 32 380 1.1E-47 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_2437 f521eca0e551a45f70b6a394bafde712 392 Gene3D G3DSA:3.40.640.10 55 293 2.8E-88 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_2437 f521eca0e551a45f70b6a394bafde712 392 SUPERFAMILY SSF53383 13 381 6.37E-73 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2437 f521eca0e551a45f70b6a394bafde712 392 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 10 387 50.944 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Spica_2437 f521eca0e551a45f70b6a394bafde712 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Spica_2437 f521eca0e551a45f70b6a394bafde712 392 Gene3D G3DSA:3.90.1150.10 34 380 2.8E-88 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0111 4a68a7f42cd9221837016ae07949da5a 671 Gene3D G3DSA:3.40.50.410 414 608 1.6E-9 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_0111 4a68a7f42cd9221837016ae07949da5a 671 SUPERFAMILY SSF53300 421 579 1.67E-10 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 SUPERFAMILY SSF57840 1 37 4.71E-16 T 13-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 7.4E-24 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 6.0E-8 T 13-10-2018 Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.38 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 Pfam PF00444 Ribosomal protein L36 1 37 3.4E-18 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0406 4eb00185a52028da4b3f73e585eac68a 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0775 c78e5128dff7e2aa6271c91bcb7a5416 440 SMART SM00642 19 368 1.3E-11 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0775 c78e5128dff7e2aa6271c91bcb7a5416 440 Pfam PF00128 Alpha amylase, catalytic domain 34 121 1.6E-18 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0775 c78e5128dff7e2aa6271c91bcb7a5416 440 Pfam PF00128 Alpha amylase, catalytic domain 152 330 1.8E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0775 c78e5128dff7e2aa6271c91bcb7a5416 440 Gene3D G3DSA:3.20.20.80 4 367 2.5E-103 T 13-10-2018 Spica_0775 c78e5128dff7e2aa6271c91bcb7a5416 440 SUPERFAMILY SSF51445 10 346 1.39E-76 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 Gene3D G3DSA:3.40.50.300 1 243 1.9E-56 T 13-10-2018 Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 Pfam PF00005 ABC transporter 276 433 2.5E-15 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 SUPERFAMILY SSF52540 244 486 3.9E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 SUPERFAMILY SSF52540 4 231 1.09E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 Gene3D G3DSA:3.40.50.300 244 501 2.0E-38 T 13-10-2018 Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 SMART SM00382 30 219 7.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0757 846b76b41b2dbf84d2a657327c037d7e 512 Pfam PF00005 ABC transporter 22 171 1.1E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 Pfam PF00365 Phosphofructokinase 74 362 1.1E-39 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 Gene3D G3DSA:3.40.50.450 10 500 2.5E-238 T 13-10-2018 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 Hamap MF_01980 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 2 551 44.499 T 13-10-2018 IPR011183 Pyrophosphate-dependent phosphofructokinase PfpB GO:0005524|GO:0006096|GO:0047334 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 SUPERFAMILY SSF53784 5 548 1.23E-159 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 198 215 7.4E-11 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 257 274 7.4E-11 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 76 95 7.4E-11 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 165 181 7.4E-11 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 Gene3D G3DSA:1.10.10.480 317 391 2.5E-238 T 13-10-2018 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 PIRSF PIRSF005677 1 551 2.6E-250 T 13-10-2018 IPR011183 Pyrophosphate-dependent phosphofructokinase PfpB GO:0005524|GO:0006096|GO:0047334 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 Gene3D G3DSA:3.40.50.460 219 534 2.5E-238 T 13-10-2018 Spica_0660 419fbb1a6194f0237ad9e2819a715399 551 TIGRFAM TIGR02477 PFKA_PPi: diphosphate--fructose-6-phosphate 1-phosphotransferase 6 550 2.2E-264 T 13-10-2018 IPR011183 Pyrophosphate-dependent phosphofructokinase PfpB GO:0005524|GO:0006096|GO:0047334 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.30.1490.20 731 800 1.1E-99 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 170 182 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 21 35 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 50 60 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.8E-65 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.40.50.20 4 118 7.6E-48 T 13-10-2018 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SMART SM01096 421 581 1.2E-49 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.40.50.1380 982 1117 2.8E-38 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF56059 130 399 2.19E-97 T 13-10-2018 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 883 890 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF52440 8 129 5.47E-42 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.30.470.20 711 974 1.1E-99 T 13-10-2018 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF52440 604 720 1.08E-43 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF52335 984 1116 1.06E-26 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Pfam PF02142 MGS-like domain 1000 1088 3.9E-21 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.40.50.20 601 707 1.8E-41 T 13-10-2018 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 581 5.8E-35 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF48108 394 480 1.83E-18 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 754 768 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF48108 516 586 3.92E-21 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SMART SM00851 999 1088 8.7E-21 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 SUPERFAMILY SSF56059 718 977 1.11E-83 T 13-10-2018 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 719 916 1.2E-28 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 130 332 2.1E-78 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_0875 cf036e7122638ab81c5334188e2dd707 1117 Gene3D G3DSA:3.30.470.20 122 400 7.9E-123 T 13-10-2018 Spica_1753 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF14338 Mrr N-terminal domain 5 90 3.8E-29 T 13-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1753 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF04471 Restriction endonuclease 158 277 2.1E-35 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Spica_1753 d7e957fb3f18cbc3711bed93de4459c6 305 SUPERFAMILY SSF52980 164 282 5.04E-17 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1753 d7e957fb3f18cbc3711bed93de4459c6 305 Gene3D G3DSA:3.40.91.100 142 302 5.8E-8 T 13-10-2018 Spica_1731 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF14338 Mrr N-terminal domain 5 90 3.8E-29 T 13-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1731 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF04471 Restriction endonuclease 158 277 2.1E-35 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Spica_1731 d7e957fb3f18cbc3711bed93de4459c6 305 SUPERFAMILY SSF52980 164 282 5.04E-17 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1731 d7e957fb3f18cbc3711bed93de4459c6 305 Gene3D G3DSA:3.40.91.100 142 302 5.8E-8 T 13-10-2018 Spica_1758 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF14338 Mrr N-terminal domain 5 90 3.8E-29 T 13-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1758 d7e957fb3f18cbc3711bed93de4459c6 305 Pfam PF04471 Restriction endonuclease 158 277 2.1E-35 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Spica_1758 d7e957fb3f18cbc3711bed93de4459c6 305 SUPERFAMILY SSF52980 164 282 5.04E-17 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1758 d7e957fb3f18cbc3711bed93de4459c6 305 Gene3D G3DSA:3.40.91.100 142 302 5.8E-8 T 13-10-2018 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF00023 Ankyrin repeat 324 356 0.024 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 154 334 7.7E-44 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 37 153 5.4E-23 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.960 625 667 8.5E-12 T 13-10-2018 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 335 448 3.2E-27 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 PRINTS PR01415 Ankyrin repeat signature 291 306 1.0E-6 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 PRINTS PR01415 Ankyrin repeat signature 374 388 1.0E-6 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SUPERFAMILY SSF48403 167 445 9.13E-64 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 449 534 1.7E-15 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SUPERFAMILY SSF48403 45 232 1.24E-32 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 489 518 2.4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 455 485 160.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 782 812 0.67 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 257 286 3.3E-7 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 751 780 110.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 424 453 1100.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 718 747 3.8E-5 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 203 237 8.4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 619 648 0.0077 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 880 911 0.0025 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 170 199 0.83 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 553 582 500.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 391 420 0.0059 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 586 615 0.0062 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 323 353 3.7 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 357 387 12.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 73 102 0.017 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 652 681 1900.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 106 135 0.02 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 685 714 0.27 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 816 845 4.3 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SMART SM00248 290 319 1.4E-4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 668 862 1.2E-42 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SUPERFAMILY SSF48403 453 613 3.98E-27 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 SUPERFAMILY SSF48403 558 933 2.17E-68 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 535 624 3.8E-19 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Gene3D G3DSA:1.25.40.20 863 934 3.5E-15 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF13857 Ankyrin repeats (many copies) 380 432 2.7E-10 T 13-10-2018 Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 723 811 1.8E-10 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 146 231 3.7E-7 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 434 516 9.6E-7 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 558 650 1.1E-12 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 860 933 8.0E-9 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 240 321 6.6E-15 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1085 870fd1ebae588ec1a992f39136424d7a 934 Pfam PF12796 Ankyrin repeats (3 copies) 51 133 5.6E-9 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1825 1ad7efe00852816afe792f33e53d312f 249 Pfam PF00121 Triosephosphate isomerase 5 245 4.5E-94 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1825 1ad7efe00852816afe792f33e53d312f 249 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1825 1ad7efe00852816afe792f33e53d312f 249 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 7.0E-59 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1825 1ad7efe00852816afe792f33e53d312f 249 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 60.927 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1825 1ad7efe00852816afe792f33e53d312f 249 Gene3D G3DSA:3.20.20.70 1 249 5.2E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1825 1ad7efe00852816afe792f33e53d312f 249 SUPERFAMILY SSF51351 1 247 6.41E-91 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1130 856e0c2159920624b854159a3610f76a 760 Gene3D G3DSA:3.40.50.150 534 744 4.0E-6 T 13-10-2018 Spica_1130 856e0c2159920624b854159a3610f76a 760 SUPERFAMILY SSF52540 16 225 8.24E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1130 856e0c2159920624b854159a3610f76a 760 SUPERFAMILY SSF53335 487 696 6.74E-6 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1130 856e0c2159920624b854159a3610f76a 760 SMART SM00382 50 167 4.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1130 856e0c2159920624b854159a3610f76a 760 Gene3D G3DSA:3.40.50.300 10 166 1.8E-43 T 13-10-2018 Spica_1130 856e0c2159920624b854159a3610f76a 760 SUPERFAMILY SSF48019 258 431 7.94E-62 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Spica_1130 856e0c2159920624b854159a3610f76a 760 Gene3D G3DSA:1.20.272.10 247 351 7.2E-45 T 13-10-2018 Spica_1130 856e0c2159920624b854159a3610f76a 760 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 160 1.6E-15 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1130 856e0c2159920624b854159a3610f76a 760 Gene3D G3DSA:1.10.8.60 167 236 1.9E-15 T 13-10-2018 Spica_1130 856e0c2159920624b854159a3610f76a 760 Pfam PF16193 AAA C-terminal domain 191 273 1.6E-25 T 13-10-2018 IPR032423 AAA C-terminal domain Spica_1130 856e0c2159920624b854159a3610f76a 760 Pfam PF12002 MgsA AAA+ ATPase C terminal 274 433 6.4E-61 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal Spica_1130 856e0c2159920624b854159a3610f76a 760 Gene3D G3DSA:1.10.3710.10 354 443 4.5E-23 T 13-10-2018 Spica_0872 544dd942ab5776f22f14b513e5171d0c 389 SMART SM00331 167 389 2.2E-15 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0872 544dd942ab5776f22f14b513e5171d0c 389 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 192 389 6.3E-25 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0872 544dd942ab5776f22f14b513e5171d0c 389 Gene3D G3DSA:3.60.40.10 132 388 2.9E-36 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 SMART SM00530 11 66 6.2E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 Gene3D G3DSA:1.10.260.40 5 79 2.8E-12 T 13-10-2018 Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 SUPERFAMILY SSF51182 74 183 1.56E-28 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 Pfam PF07883 Cupin domain 126 182 4.4E-16 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 SUPERFAMILY SSF47413 4 70 5.12E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 Pfam PF01381 Helix-turn-helix 12 66 1.3E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2324 60b3260b5f18a9ddeac01cc89c98824d 184 Gene3D G3DSA:2.60.120.10 80 183 6.2E-29 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2621 b38f038596fe6d6e59f436d021d55f15 144 SUPERFAMILY SSF52788 6 141 1.44E-42 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Spica_2621 b38f038596fe6d6e59f436d021d55f15 144 Gene3D G3DSA:3.40.50.2300 3 142 8.0E-51 T 13-10-2018 Spica_2621 b38f038596fe6d6e59f436d021d55f15 144 SMART SM00226 6 142 3.5E-40 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Spica_2621 b38f038596fe6d6e59f436d021d55f15 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 9 137 2.1E-21 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 SUPERFAMILY SSF52922 529 652 1.7E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 SUPERFAMILY SSF52518 4 321 7.69E-105 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 SUPERFAMILY SSF52518 340 520 2.36E-66 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 TIGRFAM TIGR00232 tktlase_bact: transketolase 8 651 1.8E-242 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Gene3D G3DSA:3.40.50.970 2 326 7.0E-113 T 13-10-2018 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Pfam PF02780 Transketolase, C-terminal domain 543 608 3.4E-6 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 332 1.2E-136 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Gene3D G3DSA:3.40.50.970 327 528 8.1E-72 T 13-10-2018 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Gene3D G3DSA:3.40.50.920 534 653 3.7E-34 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 SMART SM00861 348 519 2.9E-68 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_0248 a4d134e3db483f3a78dbfa7ac1b71de9 653 Pfam PF02779 Transketolase, pyrimidine binding domain 347 518 1.0E-44 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_0873 7f319d480ebdd0d0ab963298eb934be0 398 Gene3D G3DSA:3.30.70.360 201 312 4.5E-16 T 13-10-2018 Spica_0873 7f319d480ebdd0d0ab963298eb934be0 398 Gene3D G3DSA:3.40.630.10 43 362 4.5E-16 T 13-10-2018 Spica_0873 7f319d480ebdd0d0ab963298eb934be0 398 SUPERFAMILY SSF53187 38 392 1.07E-13 T 13-10-2018 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 SUPERFAMILY SSF55021 383 454 3.14E-16 T 13-10-2018 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 Gene3D G3DSA:3.30.2130.10 304 455 1.3E-34 T 13-10-2018 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 Pfam PF13840 ACT domain 314 374 2.1E-6 T 13-10-2018 IPR027795 CASTOR, ACT domain Spica_1546 7805532a23d4e089d9f0d571dd508191 456 Pfam PF13840 ACT domain 388 451 3.2E-8 T 13-10-2018 IPR027795 CASTOR, ACT domain Spica_1546 7805532a23d4e089d9f0d571dd508191 456 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 452 9.4E-101 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 Gene3D G3DSA:3.40.1160.10 3 299 7.6E-84 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1546 7805532a23d4e089d9f0d571dd508191 456 Pfam PF00696 Amino acid kinase family 4 283 2.4E-46 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 PIRSF PIRSF000726 1 456 2.1E-91 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 SUPERFAMILY SSF55021 305 377 1.72E-11 T 13-10-2018 Spica_1546 7805532a23d4e089d9f0d571dd508191 456 SUPERFAMILY SSF53633 4 287 1.7E-67 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1983 7009ae70745dcbfe114b906230ca383b 469 SUPERFAMILY SSF55424 352 466 2.92E-29 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 Gene3D G3DSA:3.50.50.60 156 271 2.3E-101 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1983 7009ae70745dcbfe114b906230ca383b 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 464 7.6E-25 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 460 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 433 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 351 372 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 6.6E-62 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 Gene3D G3DSA:3.50.50.60 2 329 2.3E-101 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 1.1E-32 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 1.1E-32 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.1E-32 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.1E-32 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 1.1E-32 T 13-10-2018 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 324 2.3E-65 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 SUPERFAMILY SSF51905 1 332 2.38E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1983 7009ae70745dcbfe114b906230ca383b 469 PIRSF PIRSF000350 1 469 1.1E-73 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 Gene3D G3DSA:3.30.390.30 352 469 1.1E-30 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_1983 7009ae70745dcbfe114b906230ca383b 469 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 1 466 5.6E-132 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF50998 81 360 6.04E-18 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF55874 902 1080 3.93E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:1.10.287.130 813 911 1.6E-23 T 13-10-2018 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 960 1080 2.2E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:3.30.565.10 913 1086 8.1E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.130.10.10 578 667 1.1E-12 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.130.10.10 457 577 8.6E-38 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SMART SM00448 1104 1217 1.7E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF00512 His Kinase A (phospho-acceptor) domain 848 913 5.8E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.130.10.10 33 208 5.0E-42 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 593 614 2.7E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 407 429 0.0052 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 502 524 0.0019 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 311 334 0.017 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 549 570 0.015 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 37 60 6.2E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 82 105 0.0034 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07494 Two component regulator propeller 129 152 0.0013 T 13-10-2018 IPR011110 Two component regulator propeller Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF07495 Y_Y_Y domain 720 783 1.2E-20 T 13-10-2018 IPR011123 Two component regulator three Y Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF47384 833 914 3.92E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF52172 1103 1229 7.83E-21 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:3.40.50.2300 1092 1225 3.4E-17 T 13-10-2018 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.60.40.10 671 794 2.9E-39 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SMART SM00387 960 1082 1.5E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.130.10.10 210 355 1.1E-27 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SMART SM00388 848 913 7.9E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Gene3D G3DSA:2.130.10.10 356 456 1.8E-27 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF63829 561 662 3.66E-7 T 13-10-2018 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 SUPERFAMILY SSF63829 322 550 1.11E-22 T 13-10-2018 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1066 1079 8.6E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1042 1060 8.6E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1008 1022 8.6E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1026 1036 8.6E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0296 535ca239ddfec69af126e2651b9eb890 1342 Pfam PF00072 Response regulator receiver domain 1106 1217 3.6E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SMART SM00387 505 598 7.6E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 510 596 2.6E-10 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Pfam PF13185 GAF domain 230 385 1.8E-14 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SMART SM00065 44 210 8.7E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SMART SM00065 227 394 8.7E-11 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SUPERFAMILY SSF55781 45 213 2.84E-15 T 13-10-2018 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SUPERFAMILY SSF55781 195 386 9.38E-26 T 13-10-2018 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Pfam PF01590 GAF domain 45 200 1.1E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 SUPERFAMILY SSF55874 501 593 1.13E-17 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Pfam PF07730 Histidine kinase 401 468 2.1E-19 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Gene3D G3DSA:3.30.450.40 18 210 5.2E-20 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Gene3D G3DSA:3.30.450.40 211 398 1.7E-31 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_2131 276b26eee60a60fcbd16d3d45d120c5b 609 Gene3D G3DSA:3.30.565.10 466 599 3.1E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1618 62204c422e855d5c617fc6d068170622 1133 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 160 1066 0.0 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SMART SM00490 815 899 1.0E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:2.30.30.840 472 530 2.4E-239 T 13-10-2018 Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:3.90.1150.50 988 1133 2.3E-33 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain Spica_1618 62204c422e855d5c617fc6d068170622 1133 SMART SM00487 589 785 1.3E-31 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1618 62204c422e855d5c617fc6d068170622 1133 Pfam PF00270 DEAD/DEAH box helicase 614 753 6.9E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF143517 978 1132 3.4E-33 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF52540 20 347 2.88E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:3.40.50.300 468 978 2.4E-239 T 13-10-2018 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SMART SM00982 992 1092 4.7E-35 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SMART SM01058 468 565 2.7E-44 T 13-10-2018 IPR003711 CarD-like/TRCF domain Spica_1618 62204c422e855d5c617fc6d068170622 1133 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 51 1084 27.463 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF52540 771 979 2.04E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1618 62204c422e855d5c617fc6d068170622 1133 Pfam PF02559 CarD-like/TRCF domain 469 564 4.7E-29 T 13-10-2018 IPR003711 CarD-like/TRCF domain Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:3.40.50.300 531 770 2.4E-239 T 13-10-2018 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF52540 513 772 9.69E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF52540 366 453 1.68E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:3.30.2060.10 143 228 9.3E-66 T 13-10-2018 Spica_1618 62204c422e855d5c617fc6d068170622 1133 Pfam PF00271 Helicase conserved C-terminal domain 796 898 1.5E-16 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1618 62204c422e855d5c617fc6d068170622 1133 Gene3D G3DSA:3.40.50.11180 40 342 9.3E-66 T 13-10-2018 Spica_1618 62204c422e855d5c617fc6d068170622 1133 SUPERFAMILY SSF141259 461 537 4.58E-22 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily Spica_1618 62204c422e855d5c617fc6d068170622 1133 Pfam PF03461 TRCF domain 994 1085 7.6E-26 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 SUPERFAMILY SSF109604 405 519 5.34E-12 T 13-10-2018 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 SMART SM00471 232 491 1.5E-9 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 Gene3D G3DSA:1.10.3210.10 215 359 8.8E-20 T 13-10-2018 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 Gene3D G3DSA:1.10.3210.10 394 528 3.4E-32 T 13-10-2018 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 Gene3D G3DSA:3.30.450.40 11 214 1.2E-43 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 SMART SM00065 32 215 1.5E-13 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 SUPERFAMILY SSF55781 17 217 4.36E-27 T 13-10-2018 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 Pfam PF01590 GAF domain 33 205 8.4E-12 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 Pfam PF13487 HD domain 408 473 9.8E-17 T 13-10-2018 Spica_0062 2f921ec9c42e185383a5f9bd9808bedc 531 SUPERFAMILY SSF109604 227 315 2.02E-10 T 13-10-2018 Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 Pfam PF02779 Transketolase, pyrimidine binding domain 471 643 2.6E-30 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 SUPERFAMILY SSF52518 471 647 1.85E-47 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 Pfam PF02780 Transketolase, C-terminal domain 666 783 5.1E-26 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 Gene3D G3DSA:3.40.50.920 660 793 1.1E-33 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 SMART SM00861 471 644 1.1E-39 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 Pfam PF00676 Dehydrogenase E1 component 166 408 7.5E-34 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 SUPERFAMILY SSF52922 658 792 4.19E-29 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 SUPERFAMILY SSF52518 31 407 7.08E-55 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1984 a2752f47b57337de1d04973cdccc7d31 818 Gene3D G3DSA:3.40.50.970 470 659 9.2E-60 T 13-10-2018 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 Pfam PF09976 Tetratricopeptide repeat-like domain 199 302 3.9E-9 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 Gene3D G3DSA:1.25.40.10 54 238 9.6E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 SMART SM00028 269 302 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 SMART SM00028 198 231 66.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 SMART SM00028 235 268 41.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 SMART SM00028 163 196 26.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 Gene3D G3DSA:1.25.40.10 242 311 2.8E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1390 bd5093c1ec8087fa4ed8e1253a012f86 311 SUPERFAMILY SSF48452 107 308 5.04E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0530 39632ac9ff0e8750ddf78226f96e0d88 291 Gene3D G3DSA:3.90.25.10 163 283 8.6E-99 T 13-10-2018 Spica_0530 39632ac9ff0e8750ddf78226f96e0d88 291 Pfam PF04321 RmlD substrate binding domain 2 289 2.4E-98 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Spica_0530 39632ac9ff0e8750ddf78226f96e0d88 291 Gene3D G3DSA:3.40.50.720 2 277 8.6E-99 T 13-10-2018 Spica_0530 39632ac9ff0e8750ddf78226f96e0d88 291 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 288 3.6E-91 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Spica_0530 39632ac9ff0e8750ddf78226f96e0d88 291 SUPERFAMILY SSF51735 2 289 5.81E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 SUPERFAMILY SSF52374 6 659 2.03E-143 T 13-10-2018 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 644 1.9E-205 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 SUPERFAMILY SSF47323 665 903 8.41E-54 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Gene3D G3DSA:1.10.730.10 651 835 1.3E-51 T 13-10-2018 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1054 14.391 T 13-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Gene3D G3DSA:3.40.50.620 15 635 1.6E-252 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 2.1E-32 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 528 541 2.1E-32 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 405 420 2.1E-32 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 568 577 2.1E-32 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 2.1E-32 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 856 0.0 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 SUPERFAMILY SSF50677 201 407 1.02E-50 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Gene3D G3DSA:3.90.740.10 198 411 1.6E-252 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 Pfam PF08264 Anticodon-binding domain of tRNA 695 843 1.5E-31 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Spica_1181 01ee2f55f980fcf515b34e1e98c8c557 1055 SUPERFAMILY SSF47323 970 1044 5.04E-5 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 SUPERFAMILY SSF47060 3 89 2.68E-30 T 13-10-2018 IPR009068 S15/NS1, RNA-binding Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 7.9E-36 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 2.0E-17 T 13-10-2018 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 20.687 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 SMART SM01387 8 88 7.6E-44 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 Pfam PF00312 Ribosomal protein S15 10 88 7.4E-33 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1357 1762e1973e9084ec6c384b93a031aa79 89 Gene3D G3DSA:1.10.287.10 1 89 6.4E-32 T 13-10-2018 Spica_0821 2b3bd32c23be6aa419f514432514eddf 77 Pfam PF13192 Thioredoxin domain 1 75 1.7E-26 T 13-10-2018 IPR012336 Thioredoxin-like fold Spica_0821 2b3bd32c23be6aa419f514432514eddf 77 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 76 4.8E-30 T 13-10-2018 IPR005243 Redox-active disulphide protein 2 Spica_0821 2b3bd32c23be6aa419f514432514eddf 77 SUPERFAMILY SSF52833 1 75 1.43E-18 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0821 2b3bd32c23be6aa419f514432514eddf 77 Gene3D G3DSA:3.40.30.10 1 75 1.1E-28 T 13-10-2018 Spica_0821 2b3bd32c23be6aa419f514432514eddf 77 PIRSF PIRSF037031 1 77 5.5E-32 T 13-10-2018 IPR005243 Redox-active disulphide protein 2 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Gene3D G3DSA:3.40.50.300 510 743 7.1E-46 T 13-10-2018 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Gene3D G3DSA:3.40.50.300 324 509 3.4E-49 T 13-10-2018 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 SUPERFAMILY SSF52540 442 725 1.81E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Gene3D G3DSA:3.90.1570.50 102 261 3.9E-34 T 13-10-2018 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 SUPERFAMILY SSF52540 244 526 6.24E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Pfam PF04851 Type III restriction enzyme, res subunit 304 491 7.4E-17 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 SMART SM00487 306 522 5.8E-12 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 5 211 3.5E-50 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 Pfam PF11867 Domain of unknown function (DUF3387) 743 1069 1.1E-128 T 13-10-2018 IPR021810 Protein of unknown function DUF3387 Spica_2695 678aef8e367fcd20079f8868b6192fd4 1073 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 333 742 5.9E-126 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 Gene3D G3DSA:1.25.40.10 274 487 9.2E-30 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SUPERFAMILY SSF48452 165 339 1.13E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SUPERFAMILY SSF48452 274 481 6.07E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 Pfam PF13432 Tetratricopeptide repeat 274 336 4.2E-5 T 13-10-2018 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 168 201 0.0049 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 202 235 1.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 270 303 0.014 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 438 471 50.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 236 269 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 304 337 37.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 338 371 0.81 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 100 133 450.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SMART SM00028 134 167 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 SUPERFAMILY SSF48452 75 175 9.86E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 Pfam PF13181 Tetratricopeptide repeat 135 167 0.11 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 Pfam PF13181 Tetratricopeptide repeat 169 201 0.0011 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2593 2e86d77175bd27194b01fa29bd006354 492 Gene3D G3DSA:1.25.40.10 45 273 7.9E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1596 faeb68902b87cf1664dd019d8cdc176c 298 Pfam PF00795 Carbon-nitrogen hydrolase 5 265 3.5E-54 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Spica_1596 faeb68902b87cf1664dd019d8cdc176c 298 Gene3D G3DSA:3.60.110.10 1 292 7.8E-111 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1596 faeb68902b87cf1664dd019d8cdc176c 298 SUPERFAMILY SSF56317 1 281 6.8E-84 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1596 faeb68902b87cf1664dd019d8cdc176c 298 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 4 281 8.4E-141 T 13-10-2018 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43 Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 Gene3D G3DSA:3.30.450.20 15 123 4.3E-5 T 13-10-2018 Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 Pfam PF07568 Histidine kinase 73 144 2.3E-12 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 SUPERFAMILY SSF55874 163 270 1.13E-12 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 Gene3D G3DSA:3.30.565.10 129 272 6.0E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 183 268 1.9E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0074 ce4c2efbfe534827811a647c280ee27e 272 SMART SM00387 176 272 5.9E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 SUPERFAMILY SSF55681 9 511 1.36E-97 T 13-10-2018 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 SUPERFAMILY SSF52954 498 602 6.05E-27 T 13-10-2018 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Pfam PF04073 Aminoacyl-tRNA editing domain 266 405 2.9E-21 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 296 9.1E-116 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Gene3D G3DSA:3.40.50.800 4 583 3.0E-231 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Pfam PF03129 Anticodon binding domain 509 596 2.2E-18 T 13-10-2018 IPR004154 Anticodon-binding Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 601 38.597 T 13-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Gene3D G3DSA:3.30.930.10 11 499 3.0E-231 T 13-10-2018 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Gene3D G3DSA:3.90.960.10 249 423 3.0E-231 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 493 1.1E-45 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 7.6E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 7.6E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 7.6E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 7.6E-15 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Spica_2807 7b29e9e7c13177d77dabe6d48144c3e5 609 SUPERFAMILY SSF55826 220 423 9.03E-23 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 65 18.213 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 59 8.1E-28 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 49 1.0E-15 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 Pfam PF02599 Global regulator protein family 1 52 7.2E-24 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 Gene3D G3DSA:3.30.70.1680 1 62 2.8E-27 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 Spica_1118 873888dd6a2a240f12f14125ebb2b256 78 SUPERFAMILY SSF117130 1 55 7.98E-19 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 Pfam PF13377 Periplasmic binding protein-like domain 198 380 1.2E-26 T 13-10-2018 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 Gene3D G3DSA:3.40.50.2300 87 372 7.9E-54 T 13-10-2018 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 Gene3D G3DSA:1.10.10.10 7 74 8.0E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 SUPERFAMILY SSF53822 87 381 2.36E-44 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 Gene3D G3DSA:3.40.50.2300 190 377 7.9E-54 T 13-10-2018 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 SUPERFAMILY SSF46785 8 71 3.55E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 5.7E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 SMART SM00345 13 72 6.0E-14 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 8.0E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1914 2d7c67b0484f1f63bca89280f750b7b6 389 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 8.0E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 SMART SM00448 6 120 2.0E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 5.5E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 5.5E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 5.5E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 SMART SM00421 164 221 2.9E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 SUPERFAMILY SSF52172 5 194 2.28E-34 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 Pfam PF00072 Response regulator receiver domain 8 121 1.1E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 Gene3D G3DSA:3.40.50.12740 6 222 4.2E-62 T 13-10-2018 Spica_0213 a2d3f770fc35dee7e15d3586ec0dfbc3 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 219 1.3E-16 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Gene3D G3DSA:3.30.70.120 212 284 2.0E-16 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_2432 58ba5c855ec4f010b38f6646870455df 284 SUPERFAMILY SSF53850 4 208 4.34E-48 T 13-10-2018 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Pfam PF01634 ATP phosphoribosyltransferase 50 201 9.6E-40 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 3 284 25.451 T 13-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Gene3D G3DSA:3.40.190.10 5 198 1.6E-52 T 13-10-2018 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 186 283 3.0E-25 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Gene3D G3DSA:3.40.190.10 89 176 1.6E-52 T 13-10-2018 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 182 4.0E-46 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Spica_2432 58ba5c855ec4f010b38f6646870455df 284 SUPERFAMILY SSF54913 212 283 1.33E-15 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_2432 58ba5c855ec4f010b38f6646870455df 284 Pfam PF08029 HisG, C-terminal domain 210 281 9.8E-20 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 SMART SM00878 335 433 9.5E-45 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 313 3.9E-71 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 SUPERFAMILY SSF52440 2 113 4.32E-47 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 SUPERFAMILY SSF51246 330 435 5.23E-33 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 Gene3D G3DSA:3.30.470.130 1 440 3.2E-175 T 13-10-2018 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 Pfam PF02785 Biotin carboxylase C-terminal domain 341 431 3.2E-30 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 1.3E-44 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 SUPERFAMILY SSF56059 83 339 9.6E-65 T 13-10-2018 Spica_2042 a65ed8f1c176257cdac641a76ec1e64c 443 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Pfam PF02811 PHP domain 6 179 3.5E-53 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 SMART SM00481 5 72 1.9E-30 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 723 8.1E-175 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Pfam PF14579 Helix-hairpin-helix motif 796 882 1.5E-24 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Gene3D G3DSA:1.10.150.870 759 873 4.4E-8 T 13-10-2018 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Gene3D G3DSA:3.20.20.140 1 275 1.7E-113 T 13-10-2018 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1016 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 SUPERFAMILY SSF89550 4 269 1.59E-38 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Gene3D G3DSA:1.10.10.1600 431 506 1.1E-23 T 13-10-2018 Spica_1964 b66f4394447bb583a78360b4d4388c4c 1142 Pfam PF01336 OB-fold nucleic acid binding domain 980 1055 8.2E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 5 316 38.922 T 13-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 SUPERFAMILY SSF75138 15 140 4.97E-31 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 13 311 1.5E-113 T 13-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 Gene3D G3DSA:3.40.1390.20 15 138 4.9E-36 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 Pfam PF07475 HPr Serine kinase C-terminal domain 140 308 2.7E-72 T 13-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 SUPERFAMILY SSF53795 142 308 1.28E-41 T 13-10-2018 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 Pfam PF02603 HPr Serine kinase N terminus 16 136 5.6E-37 T 13-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 Spica_2577 df191bfdb13b381f461ce531d682dbaf 329 Gene3D G3DSA:3.40.50.300 139 322 4.9E-73 T 13-10-2018 Spica_0937 420f8a89f438fd7635108bae0e6bf28e 109 SUPERFAMILY SSF52833 5 103 1.34E-15 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0937 420f8a89f438fd7635108bae0e6bf28e 109 Pfam PF00085 Thioredoxin 8 84 8.7E-9 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 Spica_0937 420f8a89f438fd7635108bae0e6bf28e 109 Gene3D G3DSA:3.40.30.10 1 105 3.8E-19 T 13-10-2018 Spica_2783 e033167affdf6aa771a36492e41550ad 309 Gene3D G3DSA:3.10.580.10 87 145 2.7E-11 T 13-10-2018 Spica_2783 e033167affdf6aa771a36492e41550ad 309 SUPERFAMILY SSF54631 23 149 1.01E-26 T 13-10-2018 Spica_2783 e033167affdf6aa771a36492e41550ad 309 SMART SM00116 94 142 2.6E-8 T 13-10-2018 IPR000644 CBS domain Spica_2783 e033167affdf6aa771a36492e41550ad 309 SMART SM00116 32 79 6.6E-5 T 13-10-2018 IPR000644 CBS domain Spica_2783 e033167affdf6aa771a36492e41550ad 309 Gene3D G3DSA:3.30.565.10 169 302 3.3E-12 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2783 e033167affdf6aa771a36492e41550ad 309 SUPERFAMILY SSF55874 202 297 4.93E-10 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2783 e033167affdf6aa771a36492e41550ad 309 Pfam PF00571 CBS domain 86 142 2.3E-10 T 13-10-2018 IPR000644 CBS domain Spica_2783 e033167affdf6aa771a36492e41550ad 309 Pfam PF00571 CBS domain 25 79 7.2E-10 T 13-10-2018 IPR000644 CBS domain Spica_2783 e033167affdf6aa771a36492e41550ad 309 Gene3D G3DSA:3.10.580.10 15 86 4.0E-12 T 13-10-2018 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 9 401 1.8E-81 T 13-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 SUPERFAMILY SSF51182 7 396 2.51E-86 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_1702 35b607473153c34e617bef7279f4fbe4 410 Gene3D G3DSA:2.60.120.10 14 291 6.3E-129 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_1702 35b607473153c34e617bef7279f4fbe4 410 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 134 142 - T 13-10-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 Pfam PF01238 Phosphomannose isomerase type I 12 368 2.8E-72 T 13-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 Gene3D G3DSA:1.10.441.10 158 316 6.3E-129 T 13-10-2018 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PIRSF PIRSF001480 6 408 8.4E-101 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 Gene3D G3DSA:2.60.120.10 317 397 6.3E-129 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 41 56 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 12 30 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 134 157 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 252 271 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 89 110 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 271 290 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 236 251 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1702 35b607473153c34e617bef7279f4fbe4 410 PRINTS PR00714 Phosphomannose isomerase type I signature 290 309 1.3E-60 T 13-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 7 385 147.083 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 SUPERFAMILY SSF52540 66 297 7.08E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 SUPERFAMILY SSF46785 302 374 1.5E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 SMART SM00382 97 231 6.1E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 70 372 6.3E-140 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Gene3D G3DSA:3.40.50.300 66 227 2.2E-36 T 13-10-2018 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 51 280 4.0E-103 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 297 373 1.0E-28 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Gene3D G3DSA:1.10.10.10 303 380 1.2E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Gene3D G3DSA:1.10.8.60 228 302 2.2E-28 T 13-10-2018 Spica_1342 865cd6170fefcee1994561ebf1e25b80 385 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 299 372 3.5E-31 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 PIRSF PIRSF000498 1 208 1.8E-74 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 7.1E-68 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 SUPERFAMILY SSF63380 1 87 3.91E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 Gene3D G3DSA:2.40.30.20 1 88 1.4E-29 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 SUPERFAMILY SSF63380 92 197 3.15E-31 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 Pfam PF00677 Lumazine binding domain 3 86 6.0E-23 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 Pfam PF00677 Lumazine binding domain 99 183 5.3E-22 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0167 c743064e4dcd18176fb76b5fa229a92c 223 Gene3D G3DSA:2.40.30.20 101 204 1.7E-30 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 Pfam PF00365 Phosphofructokinase 80 385 6.2E-64 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 169 185 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 202 219 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 220 238 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 257 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 298 310 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 81 100 1.2E-27 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 SUPERFAMILY SSF53784 38 438 2.09E-118 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 Gene3D G3DSA:3.40.50.450 73 267 2.9E-59 T 13-10-2018 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 PIRSF PIRSF000534 1 441 9.8E-203 T 13-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Spica_0182 6a4e43d635827c435759217c8f0b9623 455 Hamap MF_01981 ATP-dependent 6-phosphofructokinase [pfkA]. 5 437 54.782 T 13-10-2018 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type GO:0003872|GO:0005524|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 Pfam PF07196 Flagellin hook IN motif 224 263 2.2E-5 T 13-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 141 1.3E-16 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 SUPERFAMILY SSF64518 1 415 8.5E-60 T 13-10-2018 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 3 414 2.4E-82 T 13-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 Gene3D G3DSA:1.20.1330.10 41 242 7.9E-34 T 13-10-2018 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 PRINTS PR00207 Flagellin signature 36 53 2.9E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 PRINTS PR00207 Flagellin signature 75 94 2.9E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 PRINTS PR00207 Flagellin signature 110 133 2.9E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1116 3dc6f32772db3d885d65712344c1d325 415 Pfam PF00700 Bacterial flagellin C-terminal helical region 332 414 1.1E-8 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_0802 436abae0bd6906962924301af6802bad 152 SMART SM00260 3 141 3.0E-26 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0802 436abae0bd6906962924301af6802bad 152 Pfam PF01584 CheW-like domain 4 142 8.8E-29 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0802 436abae0bd6906962924301af6802bad 152 Gene3D G3DSA:2.40.50.180 23 93 1.2E-35 T 13-10-2018 Spica_0802 436abae0bd6906962924301af6802bad 152 Gene3D G3DSA:2.30.30.40 6 135 1.2E-35 T 13-10-2018 Spica_0802 436abae0bd6906962924301af6802bad 152 SUPERFAMILY SSF50341 4 144 1.23E-30 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_2662 52959a136e635d8379873c65219c48b3 79 Gene3D G3DSA:3.40.1620.10 1 42 1.5E-6 T 13-10-2018 Spica_2662 52959a136e635d8379873c65219c48b3 79 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 61 2.1E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_2662 52959a136e635d8379873c65219c48b3 79 SUPERFAMILY SSF143120 1 49 1.44E-8 T 13-10-2018 IPR036165 YefM-like superfamily Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 Gene3D G3DSA:3.20.20.80 150 522 1.4E-144 T 13-10-2018 Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 136 3.4E-27 T 13-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 Gene3D G3DSA:2.60.40.10 1 140 1.6E-30 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 Gene3D G3DSA:3.90.400.10 261 321 1.4E-144 T 13-10-2018 Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 SUPERFAMILY SSF51445 75 526 8.16E-117 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 Pfam PF00128 Alpha amylase, catalytic domain 188 492 1.8E-78 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0091 6a234f67b48397f5a4083d21aac2aa89 606 SMART SM00642 154 520 2.2E-111 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_1321 b280bdc5c964334b791b0d924dae951f 405 Gene3D G3DSA:3.90.1150.10 16 389 2.3E-120 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1321 b280bdc5c964334b791b0d924dae951f 405 Gene3D G3DSA:3.40.640.10 69 299 2.3E-120 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1321 b280bdc5c964334b791b0d924dae951f 405 Pfam PF00155 Aminotransferase class I and II 35 393 1.4E-48 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_1321 b280bdc5c964334b791b0d924dae951f 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Spica_1321 b280bdc5c964334b791b0d924dae951f 405 SUPERFAMILY SSF53383 27 404 2.96E-79 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0151 7c4e0e0a50abd71d141b8d27ecc6c104 409 Pfam PF07730 Histidine kinase 208 273 1.5E-10 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_0151 7c4e0e0a50abd71d141b8d27ecc6c104 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 400 6.3E-6 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0151 7c4e0e0a50abd71d141b8d27ecc6c104 409 SMART SM00387 313 403 6.7E-6 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0151 7c4e0e0a50abd71d141b8d27ecc6c104 409 Gene3D G3DSA:3.30.565.10 283 401 1.0E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0151 7c4e0e0a50abd71d141b8d27ecc6c104 409 SUPERFAMILY SSF55874 290 401 1.27E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Gene3D G3DSA:3.40.50.300 2 292 1.6E-104 T 13-10-2018 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SUPERFAMILY SSF52540 4 281 1.89E-95 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Gene3D G3DSA:3.30.230.10 481 681 8.2E-82 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Hamap MF_00054_B Elongation factor G [fusA]. 4 687 107.29 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 180 4.2E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SUPERFAMILY SSF54211 479 595 2.23E-39 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Pfam PF00679 Elongation factor G C-terminus 597 681 2.4E-27 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SMART SM00838 596 683 1.1E-39 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 PRINTS PR00315 GTP-binding elongation factor signature 59 67 1.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 PRINTS PR00315 GTP-binding elongation factor signature 79 89 1.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 PRINTS PR00315 GTP-binding elongation factor signature 95 106 1.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.4E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 687 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Gene3D G3DSA:3.30.70.870 430 480 1.3E-23 T 13-10-2018 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SMART SM00889 477 594 1.3E-62 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Pfam PF14492 Elongation Factor G, domain II 401 474 2.3E-33 T 13-10-2018 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Gene3D G3DSA:3.30.70.240 600 670 8.2E-82 T 13-10-2018 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Pfam PF00009 Elongation factor Tu GTP binding domain 7 280 5.5E-61 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Gene3D G3DSA:2.40.30.10 293 413 3.4E-37 T 13-10-2018 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SUPERFAMILY SSF54980 599 688 2.3E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SUPERFAMILY SSF50447 247 399 7.07E-26 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Pfam PF03144 Elongation factor Tu domain 2 322 388 9.3E-15 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 Pfam PF03764 Elongation factor G, domain IV 476 594 1.3E-41 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_0446 84ac05b31c11d876fbed5c49798826e5 696 SUPERFAMILY SSF54980 399 477 8.27E-24 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0374 d7356b6730df782d9d28604e586df344 185 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 185 21.575 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spica_0374 d7356b6730df782d9d28604e586df344 185 SMART SM00739 131 158 4.0E-5 T 13-10-2018 IPR005824 KOW Spica_0374 d7356b6730df782d9d28604e586df344 185 SUPERFAMILY SSF82679 4 118 1.09E-26 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_0374 d7356b6730df782d9d28604e586df344 185 SUPERFAMILY SSF50104 131 185 3.31E-18 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_0374 d7356b6730df782d9d28604e586df344 185 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 185 1.1E-59 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spica_0374 d7356b6730df782d9d28604e586df344 185 ProSitePatterns PS01014 Transcription termination factor nusG signature. 168 177 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Spica_0374 d7356b6730df782d9d28604e586df344 185 SMART SM00738 2 117 4.4E-29 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_0374 d7356b6730df782d9d28604e586df344 185 Gene3D G3DSA:2.30.30.30 127 185 1.3E-23 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Spica_0374 d7356b6730df782d9d28604e586df344 185 Pfam PF00467 KOW motif 134 161 7.9E-7 T 13-10-2018 IPR005824 KOW Spica_0374 d7356b6730df782d9d28604e586df344 185 PRINTS PR00338 Transcription termination factor NUSG signature 58 70 9.4E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spica_0374 d7356b6730df782d9d28604e586df344 185 PRINTS PR00338 Transcription termination factor NUSG signature 161 177 9.4E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spica_0374 d7356b6730df782d9d28604e586df344 185 PRINTS PR00338 Transcription termination factor NUSG signature 143 158 9.4E-20 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Spica_0374 d7356b6730df782d9d28604e586df344 185 Gene3D G3DSA:3.30.70.940 1 125 1.3E-34 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_0374 d7356b6730df782d9d28604e586df344 185 Pfam PF02357 Transcription termination factor nusG 5 114 5.1E-20 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 187 3.3E-49 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 Gene3D G3DSA:3.90.950.10 3 193 4.0E-61 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 PIRSF PIRSF006305 1 192 3.8E-55 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 Hamap MF_00528 Septum formation protein Maf [maf]. 3 193 28.508 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 Pfam PF02545 Maf-like protein 4 188 1.4E-50 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Spica_1414 bab50972a9e4832a78aa04c5011b4f95 195 SUPERFAMILY SSF52972 3 188 2.35E-55 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Gene3D G3DSA:3.40.1030.10 77 330 2.3E-140 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.9E-22 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 SUPERFAMILY SSF52418 69 323 7.59E-84 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 13-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 SUPERFAMILY SSF47648 1 69 2.88E-20 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Pfam PF00591 Glycosyl transferase family, a/b domain 77 304 5.2E-40 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 418 3.4E-171 T 13-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 PIRSF PIRSF000478 1 434 4.5E-163 T 13-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 5.0E-18 T 13-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Gene3D G3DSA:1.20.970.10 1 67 1.4E-28 T 13-10-2018 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 SUPERFAMILY SSF54680 332 433 1.96E-21 T 13-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 Gene3D G3DSA:3.90.1170.30 331 421 2.3E-140 T 13-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_1971 d166a0a514f5e7002e69b0cd618ea16f 435 SMART SM00941 345 419 2.5E-17 T 13-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 SUPERFAMILY SSF51445 345 694 1.21E-112 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 SUPERFAMILY SSF49303 698 776 1.58E-7 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 Gene3D G3DSA:2.60.40.10 229 318 1.9E-14 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 SUPERFAMILY SSF49303 819 879 4.24E-10 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 Gene3D G3DSA:2.60.120.260 4 192 5.0E-47 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 SUPERFAMILY SSF49303 196 310 1.69E-14 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 364 480 6.6E-5 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 Gene3D G3DSA:3.20.20.80 347 692 1.7E-130 T 13-10-2018 Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 SUPERFAMILY SSF49785 2 188 4.08E-42 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0351 bfa60df6c2c6bf6a8ce283f3d605daf0 902 Pfam PF00703 Glycosyl hydrolases family 2 239 310 4.1E-8 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SMART SM00304 188 240 2.8E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 Gene3D G3DSA:1.10.287.130 353 426 2.0E-25 T 13-10-2018 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 3.0E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 3.0E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 3.0E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 3.0E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 Gene3D G3DSA:3.30.450.20 235 350 1.0E-12 T 13-10-2018 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SMART SM00388 359 426 1.2E-22 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SMART SM00091 247 314 0.004 T 13-10-2018 IPR000014 PAS domain Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 582 1.2E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SUPERFAMILY SSF55874 415 582 3.41E-48 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 Gene3D G3DSA:3.30.565.10 431 582 4.3E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SMART SM00387 472 582 2.0E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SUPERFAMILY SSF47384 346 426 1.9E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 SUPERFAMILY SSF55785 246 345 1.38E-7 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0766 f057f5db13963aad29c73ac04e1f5478 582 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 425 3.3E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 Gene3D G3DSA:3.30.1330.80 27 241 2.3E-82 T 13-10-2018 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 SUPERFAMILY SSF117856 25 248 5.23E-75 T 13-10-2018 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 26 248 1.0E-76 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 Gene3D G3DSA:3.30.1330.80 102 225 2.3E-82 T 13-10-2018 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 PIRSF PIRSF001332 10 256 1.3E-80 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 Spica_2410 69006e77d484f0b010ba5fc14c600ea2 256 Pfam PF03306 Alpha-acetolactate decarboxylase 27 245 1.0E-80 T 13-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 SMART SM00062 33 257 1.6E-4 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 SUPERFAMILY SSF55874 501 631 1.09E-14 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 SMART SM00387 538 632 2.9E-4 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Gene3D G3DSA:3.30.450.20 363 493 6.9E-12 T 13-10-2018 Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 SUPERFAMILY SSF55785 298 420 1.8E-9 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Gene3D G3DSA:3.40.190.10 33 253 2.4E-39 T 13-10-2018 Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Gene3D G3DSA:3.40.190.10 118 210 2.4E-39 T 13-10-2018 Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Pfam PF07568 Histidine kinase 442 515 1.0E-25 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 224 2.3E-31 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Pfam PF08448 PAS fold 319 423 2.6E-10 T 13-10-2018 IPR013656 PAS fold-4 Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 Gene3D G3DSA:3.30.565.10 499 632 4.8E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0554 0912d167717589ed7d9f4a980eec03c5 632 SUPERFAMILY SSF53850 34 258 4.71E-38 T 13-10-2018 Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 Gene3D G3DSA:3.40.50.12740 79 204 1.1E-28 T 13-10-2018 Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 SUPERFAMILY SSF52172 79 197 9.25E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 Gene3D G3DSA:1.10.1660.10 11 66 7.0E-6 T 13-10-2018 Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 Pfam PF12728 Helix-turn-helix domain 15 60 1.0E-7 T 13-10-2018 Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 Pfam PF00072 Response regulator receiver domain 81 194 1.4E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0470 15e22a8726477ceb0b019229cde1c1fc 207 SMART SM00448 79 194 3.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0259 eae2df7add17b4da2593941856597b8b 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 140 4.5E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0259 eae2df7add17b4da2593941856597b8b 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 173 4.5E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0259 eae2df7add17b4da2593941856597b8b 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.5E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0259 eae2df7add17b4da2593941856597b8b 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 175 195 4.5E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0259 eae2df7add17b4da2593941856597b8b 229 Gene3D G3DSA:1.10.150.240 27 111 1.5E-31 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_0259 eae2df7add17b4da2593941856597b8b 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 121 210 3.8E-8 T 13-10-2018 Spica_0259 eae2df7add17b4da2593941856597b8b 229 SUPERFAMILY SSF56784 12 222 7.79E-25 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0259 eae2df7add17b4da2593941856597b8b 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 148 210 3.8E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0259 eae2df7add17b4da2593941856597b8b 229 Gene3D G3DSA:3.40.50.1000 14 209 1.5E-31 T 13-10-2018 IPR023214 HAD superfamily Spica_1948 97851aa3c6562c1680e894c59617471b 616 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 522 613 2.1E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1948 97851aa3c6562c1680e894c59617471b 616 Pfam PF02743 Cache domain 69 261 8.4E-18 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_1948 97851aa3c6562c1680e894c59617471b 616 Gene3D G3DSA:3.30.565.10 477 616 1.9E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1948 97851aa3c6562c1680e894c59617471b 616 SUPERFAMILY SSF103190 157 231 6.28E-12 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_1948 97851aa3c6562c1680e894c59617471b 616 Gene3D G3DSA:3.30.450.20 158 224 1.4E-27 T 13-10-2018 Spica_1948 97851aa3c6562c1680e894c59617471b 616 Gene3D G3DSA:3.30.450.20 225 309 1.4E-27 T 13-10-2018 Spica_1948 97851aa3c6562c1680e894c59617471b 616 SMART SM00387 515 615 1.3E-10 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1948 97851aa3c6562c1680e894c59617471b 616 SUPERFAMILY SSF55874 484 613 1.96E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1948 97851aa3c6562c1680e894c59617471b 616 Gene3D G3DSA:3.30.450.20 394 471 4.2E-8 T 13-10-2018 Spica_1948 97851aa3c6562c1680e894c59617471b 616 Pfam PF07568 Histidine kinase 420 493 7.5E-24 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 2.5E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 2.5E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Gene3D G3DSA:1.10.8.60 314 393 8.5E-29 T 13-10-2018 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 SUPERFAMILY SSF52172 3 188 2.7E-48 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Pfam PF02954 Bacterial regulatory protein, Fis family 405 445 3.6E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Pfam PF00072 Response regulator receiver domain 6 112 1.2E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 SMART SM00382 163 306 9.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Gene3D G3DSA:1.10.10.60 404 446 1.4E-13 T 13-10-2018 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Gene3D G3DSA:3.40.50.2300 4 122 7.0E-38 T 13-10-2018 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 SMART SM00448 3 114 1.7E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Pfam PF00158 Sigma-54 interaction domain 144 310 2.4E-71 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 SUPERFAMILY SSF46689 356 445 8.24E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 Gene3D G3DSA:3.40.50.300 128 313 2.5E-68 T 13-10-2018 Spica_1509 0642a3dc377c1df11f73f4bdcf7bc8bf 455 SUPERFAMILY SSF52540 143 386 3.55E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0544 b9aed84fa200e423b8012fac3260c927 554 SUPERFAMILY SSF109755 340 549 3.14E-19 T 13-10-2018 Spica_0544 b9aed84fa200e423b8012fac3260c927 554 Pfam PF02690 Na+/Pi-cotransporter 16 155 3.4E-48 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 Spica_0544 b9aed84fa200e423b8012fac3260c927 554 Pfam PF02690 Na+/Pi-cotransporter 180 258 3.3E-13 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 Spica_0544 b9aed84fa200e423b8012fac3260c927 554 Pfam PF01895 PhoU domain 355 441 7.3E-7 T 13-10-2018 IPR026022 PhoU domain Spica_0544 b9aed84fa200e423b8012fac3260c927 554 Gene3D G3DSA:1.20.58.220 349 552 1.5E-9 T 13-10-2018 IPR038078 PhoU-like domain superfamily Spica_0544 b9aed84fa200e423b8012fac3260c927 554 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 6 322 6.5E-82 T 13-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 Spica_1978 41de0522261c967256e951ec7083aac1 269 Pfam PF02535 ZIP Zinc transporter 118 264 2.9E-18 T 13-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spica_1632 210816ab1bddb6be47b5a3ed97b9d181 353 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 122 337 6.9E-46 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Spica_1632 210816ab1bddb6be47b5a3ed97b9d181 353 SUPERFAMILY SSF53187 121 340 2.61E-42 T 13-10-2018 Spica_1632 210816ab1bddb6be47b5a3ed97b9d181 353 SMART SM00646 190 337 3.5E-26 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Spica_1632 210816ab1bddb6be47b5a3ed97b9d181 353 Gene3D G3DSA:3.40.630.40 111 347 1.0E-57 T 13-10-2018 Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 Gene3D G3DSA:1.10.150.130 1 96 8.3E-24 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 Pfam PF00589 Phage integrase family 131 281 1.5E-42 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 49.843 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 85 8.1E-20 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 SUPERFAMILY SSF56349 5 288 2.71E-56 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spica_1676 b61cce20edfffa9a18b2a2de1e6bfb6a 302 Gene3D G3DSA:1.10.443.10 110 297 2.9E-53 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Spica_0907 7198f9cb0d047dfcab0eda6f2ca223c4 309 SUPERFAMILY SSF48317 95 264 1.44E-25 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily Spica_0907 7198f9cb0d047dfcab0eda6f2ca223c4 309 SMART SM00014 138 259 3.5E-6 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_0907 7198f9cb0d047dfcab0eda6f2ca223c4 309 Gene3D G3DSA:1.20.144.10 90 268 3.4E-16 T 13-10-2018 Spica_0907 7198f9cb0d047dfcab0eda6f2ca223c4 309 Pfam PF01569 PAP2 superfamily 142 264 5.8E-17 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_2837 140aeee9a9fcb7282ee4d066bd44fb02 283 SMART SM00382 31 224 1.7E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2837 140aeee9a9fcb7282ee4d066bd44fb02 283 SUPERFAMILY SSF52540 8 229 4.69E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2837 140aeee9a9fcb7282ee4d066bd44fb02 283 Pfam PF00005 ABC transporter 34 166 4.6E-15 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2837 140aeee9a9fcb7282ee4d066bd44fb02 283 Gene3D G3DSA:3.40.50.300 7 267 1.9E-36 T 13-10-2018 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 1.3E-14 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF03725 3' exoribonuclease family, domain 2 458 526 6.1E-6 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF50249 618 694 1.95E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF55666 451 558 5.76E-29 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF55666 143 230 3.14E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF54211 4 142 2.58E-41 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Gene3D G3DSA:3.30.230.70 1 228 2.9E-72 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 PIRSF PIRSF005499 1 703 1.2E-299 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF54211 293 486 9.62E-50 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 318 1.1E-16 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Gene3D G3DSA:3.30.230.70 234 547 1.3E-115 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Gene3D G3DSA:3.30.1370.10 548 619 6.6E-19 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF00013 KH domain 555 610 9.4E-12 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SUPERFAMILY SSF54791 553 638 1.02E-21 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Gene3D G3DSA:2.40.50.140 620 690 3.6E-26 T 13-10-2018 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF00575 S1 RNA binding domain 617 686 3.5E-18 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF01138 3' exoribonuclease family, domain 1 323 454 2.9E-20 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Pfam PF01138 3' exoribonuclease family, domain 1 14 142 4.2E-15 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 8 687 5.7E-300 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 691 29.941 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SMART SM00316 618 688 7.1E-23 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1358 475fa0dbb3f127acf62361c83c68e8cd 703 SMART SM00322 550 615 4.3E-15 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 SUPERFAMILY SSF52540 62 401 7.49E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Gene3D G3DSA:3.40.50.300 58 314 9.9E-108 T 13-10-2018 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 SMART SM01086 316 410 6.6E-28 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 309 1.3E-47 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 SMART SM00994 12 52 1.4E-17 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Gene3D G3DSA:1.10.8.60 315 417 5.6E-36 T 13-10-2018 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 414 51.072 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 13 411 2.4E-189 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Gene3D G3DSA:3.30.50.30 5 52 3.1E-16 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 SUPERFAMILY SSF57716 13 49 3.56E-8 T 13-10-2018 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 388 6.4E-15 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 Pfam PF06689 ClpX C4-type zinc finger 14 51 3.4E-18 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Spica_1110 d29fe668902ffdc93e7ea4e24866c54d 417 SMART SM00382 112 270 4.7E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 SUPERFAMILY SSF52540 9 1029 6.21E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 Gene3D G3DSA:3.40.50.300 1 304 2.0E-42 T 13-10-2018 Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 Gene3D G3DSA:3.40.50.300 742 1048 3.7E-26 T 13-10-2018 Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 SUPERFAMILY SSF52540 1 298 7.8E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 Pfam PF13476 AAA domain 5 237 9.6E-28 T 13-10-2018 IPR038729 Rad50/SbcC-type AAA domain Spica_1890 bac995b9b2dd1bfa899df84ea2a0d93a 1053 Pfam PF13558 Putative exonuclease SbcCD, C subunit 951 1011 2.0E-11 T 13-10-2018 Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 Pfam PF00294 pfkB family carbohydrate kinase 12 301 6.6E-45 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 6 315 6.6E-96 T 13-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 SUPERFAMILY SSF53613 8 303 1.36E-62 T 13-10-2018 IPR029056 Ribokinase-like Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 PIRSF PIRSF000535 3 318 1.6E-82 T 13-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 Gene3D G3DSA:3.40.1190.20 5 322 1.2E-95 T 13-10-2018 IPR029056 Ribokinase-like Spica_2248 f64fd64afff1f2411fdab7994f40652d 322 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 6 315 2.1E-95 T 13-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 Spica_0141 6fd750ee2a202068b8a52a443933f4a5 139 Pfam PF07009 NusG domain II 33 128 2.3E-21 T 13-10-2018 IPR024045 NusG, domain 2 Spica_0141 6fd750ee2a202068b8a52a443933f4a5 139 SUPERFAMILY SSF82004 63 125 5.75E-5 T 13-10-2018 Spica_0141 6fd750ee2a202068b8a52a443933f4a5 139 Gene3D G3DSA:2.60.320.10 35 137 3.1E-22 T 13-10-2018 IPR038690 NusG, domain 2 superfamily Spica_1263 f38e604202b823fd637252303dbdc9c7 454 Gene3D G3DSA:3.30.300.30 346 451 2.1E-32 T 13-10-2018 Spica_1263 f38e604202b823fd637252303dbdc9c7 454 Pfam PF14535 AMP-binding enzyme C-terminal domain 354 450 3.8E-29 T 13-10-2018 IPR028154 AMP-dependent ligase, C-terminal Spica_1263 f38e604202b823fd637252303dbdc9c7 454 Pfam PF00501 AMP-binding enzyme 97 304 4.0E-18 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_1263 f38e604202b823fd637252303dbdc9c7 454 PIRSF PIRSF006444 16 452 1.5E-172 T 13-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Spica_1263 f38e604202b823fd637252303dbdc9c7 454 Gene3D G3DSA:3.40.50.12780 18 345 5.4E-125 T 13-10-2018 Spica_1263 f38e604202b823fd637252303dbdc9c7 454 SUPERFAMILY SSF56801 70 415 1.11E-57 T 13-10-2018 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 SUPERFAMILY SSF52374 11 131 3.16E-14 T 13-10-2018 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 SUPERFAMILY SSF51621 93 428 9.42E-64 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 Pfam PF13714 Phosphoenolpyruvate phosphomutase 148 406 3.1E-63 T 13-10-2018 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 Gene3D G3DSA:3.40.50.620 2 135 3.4E-24 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 Gene3D G3DSA:3.20.20.60 136 432 1.4E-71 T 13-10-2018 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 1.9E-9 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 TIGRFAM TIGR02320 PEP_mutase: phosphoenolpyruvate mutase 148 431 8.7E-121 T 13-10-2018 IPR012698 Phosphoenolpyruvate phosphomutase, core GO:0050188 KEGG: 00440+5.4.2.9|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7419|MetaCyc: PWY-7510|MetaCyc: PWY-7769 Spica_1331 ef70f51d3d582c743038f89d6f92c4a7 432 Pfam PF01467 Cytidylyltransferase-like 11 96 9.2E-10 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_0312 758e770b398d2b32b5fae45f3d32a3ec 282 SUPERFAMILY SSF161098 9 282 1.4E-63 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0312 758e770b398d2b32b5fae45f3d32a3ec 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 274 6.0E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0312 758e770b398d2b32b5fae45f3d32a3ec 282 Gene3D G3DSA:1.10.3720.10 2 273 1.5E-55 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1108 101d37f2d9e14b02920e1bf5255fb777 379 SUPERFAMILY SSF53756 7 373 2.12E-76 T 13-10-2018 Spica_1108 101d37f2d9e14b02920e1bf5255fb777 379 Gene3D G3DSA:3.40.50.2000 172 355 1.4E-59 T 13-10-2018 Spica_1108 101d37f2d9e14b02920e1bf5255fb777 379 Pfam PF13439 Glycosyltransferase Family 4 16 175 9.1E-17 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_1108 101d37f2d9e14b02920e1bf5255fb777 379 Gene3D G3DSA:3.40.50.2000 97 369 1.4E-59 T 13-10-2018 Spica_1108 101d37f2d9e14b02920e1bf5255fb777 379 Pfam PF00534 Glycosyl transferases group 1 196 352 3.1E-31 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_1534 ba9eca60301c65de1ec49a61d46ac583 244 Gene3D G3DSA:3.30.1330.60 83 243 3.2E-43 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_1534 ba9eca60301c65de1ec49a61d46ac583 244 Pfam PF00691 OmpA family 129 232 5.9E-19 T 13-10-2018 IPR006665 OmpA-like domain Spica_1534 ba9eca60301c65de1ec49a61d46ac583 244 SUPERFAMILY SSF103088 117 238 4.45E-28 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_1534 ba9eca60301c65de1ec49a61d46ac583 244 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 55 4.4E-18 T 13-10-2018 IPR025713 Motility protein B, N-terminal domain Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 SUPERFAMILY SSF55821 9 212 1.13E-59 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 Gene3D G3DSA:3.90.870.10 3 213 5.1E-77 T 13-10-2018 Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 Pfam PF01300 Telomere recombination 18 199 1.5E-54 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 Gene3D G3DSA:3.40.50.11030 214 345 7.2E-19 T 13-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 PIRSF PIRSF004930 2 346 1.6E-103 T 13-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 Pfam PF03481 Putative GTP-binding controlling metal-binding 203 339 5.0E-19 T 13-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain Spica_2706 4174aeba5a97c777bc03adfe457941b7 347 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 210 3.5E-59 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 Spica_1200 ff4641bb4f9a2ed7673f31066d6fa610 281 Pfam PF00809 Pterin binding enzyme 22 261 5.9E-83 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1200 ff4641bb4f9a2ed7673f31066d6fa610 281 SUPERFAMILY SSF51717 11 278 3.14E-96 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1200 ff4641bb4f9a2ed7673f31066d6fa610 281 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 275 8.8E-97 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Spica_1200 ff4641bb4f9a2ed7673f31066d6fa610 281 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 54 67 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1200 ff4641bb4f9a2ed7673f31066d6fa610 281 Gene3D G3DSA:3.20.20.20 7 281 8.6E-106 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 Pfam PF01880 Desulfoferrodoxin 42 123 3.6E-22 T 13-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 34 2.3E-19 T 13-10-2018 IPR004462 Desulforodoxin domain GO:0005506 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 SUPERFAMILY SSF57802 4 37 7.46E-13 T 13-10-2018 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 3 37 2.5E-20 T 13-10-2018 IPR004462 Desulforodoxin domain GO:0005506 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 Gene3D G3DSA:2.20.28.100 1 39 4.7E-19 T 13-10-2018 IPR038094 Desulforodoxin domain superfamily Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 124 2.5E-67 T 13-10-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 Gene3D G3DSA:2.60.40.730 40 124 1.9E-33 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 41 123 1.1E-27 T 13-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 Spica_1836 4fd9c9bcad611cc2eea2bdadc999fab9 124 SUPERFAMILY SSF49367 39 123 1.57E-32 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 SMART SM00382 519 704 6.5E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 Pfam PF00664 ABC transporter transmembrane region 207 444 4.3E-33 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 SUPERFAMILY SSF52540 489 728 9.35E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 Gene3D G3DSA:3.40.50.300 485 734 9.1E-81 T 13-10-2018 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 Gene3D G3DSA:1.20.1560.10 185 471 2.7E-61 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 SUPERFAMILY SSF90123 4 477 3.79E-70 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_0301 32eaa23909e24af2dc0411ac398bde29 735 Pfam PF00005 ABC transporter 512 656 3.9E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 SUPERFAMILY SSF52540 268 505 5.16E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 SMART SM00382 29 217 1.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 SMART SM00382 300 502 12.0 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 Pfam PF00005 ABC transporter 291 452 2.5E-11 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 Pfam PF00005 ABC transporter 21 169 2.1E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 Gene3D G3DSA:3.40.50.300 1 236 4.4E-48 T 13-10-2018 Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 SUPERFAMILY SSF52540 3 226 1.61E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2658 0dc2d8596effca55f37f5e0ddec9fe3b 541 Gene3D G3DSA:3.40.50.300 268 525 1.1E-33 T 13-10-2018 Spica_0576 a33db463785be30323654697470f3f3c 119 SUPERFAMILY SSF49764 14 119 1.08E-26 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_0576 a33db463785be30323654697470f3f3c 119 Pfam PF00011 Hsp20/alpha crystallin family 22 119 1.0E-18 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Spica_0576 a33db463785be30323654697470f3f3c 119 Gene3D G3DSA:2.60.40.790 1 119 1.2E-26 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_1518 a0a80c1111f0e514341e8f4e7d4e4dd4 203 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 58 198 0.003 T 13-10-2018 Spica_1287 097bba6431a1f6c1d4aab85e3dcb1f5e 244 Pfam PF12679 ABC-2 family transporter protein 64 219 4.8E-13 T 13-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 SMART SM00363 5 64 2.0E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 Pfam PF01479 S4 domain 6 51 8.8E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 Gene3D G3DSA:3.30.70.580 66 228 5.8E-47 T 13-10-2018 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 Gene3D G3DSA:3.10.290.10 1 59 8.4E-21 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 Pfam PF00849 RNA pseudouridylate synthase 66 195 1.6E-16 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 SUPERFAMILY SSF55120 65 229 3.45E-35 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 Gene3D G3DSA:3.30.70.1560 133 212 5.8E-47 T 13-10-2018 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 SUPERFAMILY SSF55174 5 60 2.55E-14 T 13-10-2018 Spica_1377 5c8ca65ae74ec0ebcadb4411e3e4a114 250 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 225 6.2E-39 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 Pfam PF13377 Periplasmic binding protein-like domain 167 325 9.5E-24 T 13-10-2018 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 SMART SM00354 1 71 9.2E-29 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 13-10-2018 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 Gene3D G3DSA:3.40.50.2300 55 301 2.0E-47 T 13-10-2018 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.0E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.0E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 Gene3D G3DSA:3.40.50.2300 159 287 2.0E-47 T 13-10-2018 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 SUPERFAMILY SSF53822 60 317 3.85E-39 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2626 396aa577bf01c9ad798a557cc9845454 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.7E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 Gene3D G3DSA:1.10.260.40 1 54 1.3E-24 T 13-10-2018 Spica_2626 396aa577bf01c9ad798a557cc9845454 326 SUPERFAMILY SSF47413 1 58 4.16E-19 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 1.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 1.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 1.1E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 Gene3D G3DSA:3.40.50.720 2 276 7.0E-57 T 13-10-2018 Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 1.4E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 95bc4f922ace811404e98f87e13c0919 278 SUPERFAMILY SSF51735 17 274 2.01E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0066 95bc4f922ace811404e98f87e13c0919 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_0066 95bc4f922ace811404e98f87e13c0919 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 273 1.1E-40 T 13-10-2018 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 PRINTS PR00988 Uridine kinase signature 318 329 1.6E-7 T 13-10-2018 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 PRINTS PR00988 Uridine kinase signature 363 378 1.6E-7 T 13-10-2018 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 PRINTS PR00988 Uridine kinase signature 286 303 1.6E-7 T 13-10-2018 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 SUPERFAMILY SSF52540 282 483 5.05E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 SMART SM00382 285 446 5.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 Gene3D G3DSA:3.40.50.300 230 499 1.4E-58 T 13-10-2018 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 288 488 4.2E-16 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 SUPERFAMILY SSF55186 65 230 3.66E-28 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Spica_1665 8aeb6e749b1744e535cb674da3d0e869 552 Gene3D G3DSA:3.30.980.10 65 207 2.4E-21 T 13-10-2018 Spica_2438 82474d23f521383813607a4646f06467 465 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 45 465 35.783 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 66 464 1.0E-137 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 Pfam PF00815 Histidinol dehydrogenase 60 464 6.7E-142 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PIRSF PIRSF000099 43 465 3.3E-132 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 Gene3D G3DSA:3.40.50.1980 270 386 1.1E-110 T 13-10-2018 Spica_2438 82474d23f521383813607a4646f06467 465 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 266 298 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 Gene3D G3DSA:3.40.50.1980 64 269 1.1E-110 T 13-10-2018 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 357 382 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 266 287 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 398 416 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 172 198 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 207 233 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 66 90 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 237 262 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 PRINTS PR00083 Histidinol dehydrogenase signature 288 307 6.0E-79 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Spica_2438 82474d23f521383813607a4646f06467 465 SUPERFAMILY SSF53720 60 462 7.85E-64 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 SUPERFAMILY SSF56219 1 257 1.7E-75 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 1.1E-22 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 Gene3D G3DSA:3.60.10.10 1 258 9.6E-88 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 1.4E-94 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Spica_2019 86e44ce5a680508e3c2727704f181a7e 258 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 6.4E-86 T 13-10-2018 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 Gene3D G3DSA:2.40.33.10 73 180 6.0E-184 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 Gene3D G3DSA:3.40.1380.20 347 482 6.0E-184 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 Pfam PF00224 Pyruvate kinase, barrel domain 5 349 9.5E-136 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 SUPERFAMILY SSF52009 479 596 5.89E-5 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 Gene3D G3DSA:3.20.20.60 5 346 6.0E-184 T 13-10-2018 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 228 254 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 62 78 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 305 323 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 198 212 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 280 304 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 255 279 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 PRINTS PR01050 Pyruvate kinase family signature 324 340 7.4E-74 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 486 3.7E-168 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 SUPERFAMILY SSF52935 335 487 9.42E-35 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 SUPERFAMILY SSF50800 73 177 6.11E-21 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 Pfam PF02887 Pyruvate kinase, alpha/beta domain 371 484 3.4E-30 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Spica_0776 ad7bca4f9e4dc2451e811a0217c40455 599 SUPERFAMILY SSF51621 3 352 4.89E-98 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 636 654 1.2E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 1.2E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 1.2E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 669 683 1.2E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SMART SM00382 221 361 5.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SMART SM00382 558 707 1.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SUPERFAMILY SSF52540 182 483 9.61E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1243 cfa31a89c0aec715822db199366ec42c 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 316 328 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 342 3.6E-14 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF02151 UvrB/uvrC motif 438 473 7.0E-9 T 13-10-2018 IPR001943 UVR domain GO:0005515 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SUPERFAMILY SSF52540 507 807 7.53E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:1.10.8.60 367 502 9.9E-43 T 13-10-2018 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 735 810 2.6E-22 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SMART SM01086 735 824 1.8E-27 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:3.40.50.300 173 364 6.3E-72 T 13-10-2018 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 145 2.1E-11 T 13-10-2018 IPR004176 Clp, N-terminal Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 4.8E-11 T 13-10-2018 IPR004176 Clp, N-terminal Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:1.10.1780.10 1 149 1.5E-34 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:3.40.50.300 511 733 7.0E-81 T 13-10-2018 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:1.10.8.60 735 835 5.5E-24 T 13-10-2018 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 557 729 8.4E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 SUPERFAMILY SSF81923 5 145 5.76E-23 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_1243 cfa31a89c0aec715822db199366ec42c 848 Gene3D G3DSA:4.10.860.10 430 488 9.9E-43 T 13-10-2018 Spica_1621 1e855656b6db603855517595f5055be3 267 Gene3D G3DSA:3.20.20.140 3 267 1.3E-35 T 13-10-2018 Spica_1621 1e855656b6db603855517595f5055be3 267 Pfam PF01026 TatD related DNase 4 263 2.9E-34 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_1621 1e855656b6db603855517595f5055be3 267 SUPERFAMILY SSF51556 4 263 2.01E-34 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_1621 1e855656b6db603855517595f5055be3 267 PIRSF PIRSF005902 1 264 1.5E-31 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 Gene3D G3DSA:1.10.287.130 195 271 1.4E-10 T 13-10-2018 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 269 7.1E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 SUPERFAMILY SSF55874 265 418 4.98E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 SMART SM00388 210 275 8.7E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 SMART SM00387 311 420 1.8E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 SUPERFAMILY SSF47384 199 270 1.06E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 398 3.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 3.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 3.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 417 3.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 Gene3D G3DSA:3.30.565.10 276 422 7.8E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1192 6c75553b9e6b8d0080101ab207c7a1b8 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 419 7.3E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 474 6.7E-23 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 SUPERFAMILY SSF53067 16 263 3.42E-33 T 13-10-2018 Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 Gene3D G3DSA:3.30.420.40 265 530 5.1E-22 T 13-10-2018 Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 16 242 3.7E-20 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 SUPERFAMILY SSF53067 271 519 4.75E-14 T 13-10-2018 Spica_0056 6c2a2256fe0a5ce50bc9694d1d8247dd 532 Gene3D G3DSA:3.30.420.40 11 264 6.2E-40 T 13-10-2018 Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 228 456 2.5E-51 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 Gene3D G3DSA:3.30.70.20 112 168 2.8E-13 T 13-10-2018 Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 Gene3D G3DSA:3.30.70.20 171 219 1.9E-14 T 13-10-2018 Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 196 207 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 Gene3D G3DSA:3.40.950.20 266 477 2.4E-31 T 13-10-2018 Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 Pfam PF13237 4Fe-4S dicluster domain 142 207 5.4E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 TIGRFAM TIGR04105 FeFe_hydrog_B1: [FeFe] hydrogenase, group B1/B3 4 461 1.6E-166 T 13-10-2018 IPR027631 [FeFe] hydrogenase, group B1/B3 Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 SUPERFAMILY SSF53920 195 466 5.36E-63 T 13-10-2018 IPR009016 Iron hydrogenase Spica_0221 7d5cb0b9c5bc8c3756da2786818e6182 500 SUPERFAMILY SSF54862 104 215 4.75E-16 T 13-10-2018 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 SUPERFAMILY SSF53271 41 166 6.48E-16 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 137 1.5E-17 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 Gene3D G3DSA:3.40.50.2020 167 328 1.7E-62 T 13-10-2018 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 42 351 7.3E-46 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 SMART SM01400 5 137 4.3E-7 T 13-10-2018 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 SUPERFAMILY SSF53271 196 350 1.97E-23 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 Gene3D G3DSA:3.40.50.2020 41 339 1.7E-62 T 13-10-2018 Spica_1372 c39ac84fcfe501153988a1fa4da2c3b7 366 Pfam PF00156 Phosphoribosyl transferase domain 199 284 2.1E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 SUPERFAMILY SSF75304 16 493 3.27E-119 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 Pfam PF01425 Amidase 273 485 3.2E-36 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 Pfam PF01425 Amidase 24 206 6.8E-81 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 Gene3D G3DSA:3.90.1300.10 10 504 3.7E-144 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 ProSitePatterns PS00571 Amidases signature. 116 147 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Spica_0988 21d6994a7fb50de9eb054c3ff46b331a 508 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 1 496 68.079 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Gene3D G3DSA:3.40.50.300 539 771 1.1E-15 T 13-10-2018 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Pfam PF00270 DEAD/DEAH box helicase 587 750 1.6E-9 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 352 525 2.1E-26 T 13-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 SUPERFAMILY SSF109604 346 442 2.41E-8 T 13-10-2018 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 SMART SM00487 562 776 5.5E-5 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Pfam PF08279 HTH domain 10 52 7.7E-6 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 SUPERFAMILY SSF46785 8 50 7.49E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Gene3D G3DSA:3.40.50.300 780 929 7.9E-7 T 13-10-2018 Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Pfam PF13280 WYL domain 144 321 6.8E-33 T 13-10-2018 IPR026881 WYL domain Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 SUPERFAMILY SSF52540 580 904 2.8E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Gene3D G3DSA:1.10.3210.30 343 484 3.7E-12 T 13-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 587 906 1.6E-35 T 13-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core Spica_1929 212856d807f8f9ae175771a7742de9e2 1080 Pfam PF01966 HD domain 353 442 1.0E-7 T 13-10-2018 IPR006674 HD domain Spica_2217 61da046eada610565e1174b948fb4e9e 513 Pfam PF00005 ABC transporter 22 172 2.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2217 61da046eada610565e1174b948fb4e9e 513 SUPERFAMILY SSF52540 6 228 2.33E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2217 61da046eada610565e1174b948fb4e9e 513 Gene3D G3DSA:3.40.50.300 2 240 1.5E-55 T 13-10-2018 Spica_2217 61da046eada610565e1174b948fb4e9e 513 Pfam PF00005 ABC transporter 277 431 6.0E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2217 61da046eada610565e1174b948fb4e9e 513 SMART SM00382 31 220 1.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2217 61da046eada610565e1174b948fb4e9e 513 SMART SM00382 286 480 2.8E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2217 61da046eada610565e1174b948fb4e9e 513 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2217 61da046eada610565e1174b948fb4e9e 513 Gene3D G3DSA:3.40.50.300 264 513 2.9E-45 T 13-10-2018 Spica_2217 61da046eada610565e1174b948fb4e9e 513 SUPERFAMILY SSF52540 273 491 5.84E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 Gene3D G3DSA:1.10.10.60 348 400 1.3E-19 T 13-10-2018 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 352 394 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 Gene3D G3DSA:1.10.10.60 296 347 6.3E-14 T 13-10-2018 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 Gene3D G3DSA:3.40.50.12740 3 181 2.8E-32 T 13-10-2018 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 Pfam PF00072 Response regulator receiver domain 4 116 4.4E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 SMART SM00448 2 116 5.5E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 SUPERFAMILY SSF46689 351 400 3.63E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 SUPERFAMILY SSF52172 1 155 7.83E-34 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 SMART SM00342 315 398 4.5E-32 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 382 398 4.8E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 367 382 4.8E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2214 27ef76a1077346a3c9a7eb2f5cffd8a0 404 Pfam PF12833 Helix-turn-helix domain 322 399 2.1E-22 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_1086 390d2ffac24c6f72136731484ccf8a41 223 Gene3D G3DSA:3.40.50.620 1 223 2.5E-35 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1086 390d2ffac24c6f72136731484ccf8a41 223 Pfam PF01171 PP-loop family 23 180 6.7E-16 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Spica_1086 390d2ffac24c6f72136731484ccf8a41 223 PIRSF PIRSF004976 1 223 8.1E-48 T 13-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 Spica_1086 390d2ffac24c6f72136731484ccf8a41 223 SUPERFAMILY SSF52402 9 205 1.87E-36 T 13-10-2018 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 40.33 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PIRSF PIRSF002133 1 124 9.8E-56 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.0E-42 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 SUPERFAMILY SSF50249 2 123 6.6E-53 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 Gene3D G3DSA:2.40.50.140 1 124 6.1E-64 T 13-10-2018 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 5.1E-70 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0381 acfa0042b1aa139e8d37343a3ed56e16 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Hamap MF_00205 UvrABC system protein A [uvrA]. 18 955 23.233 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 20 940 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 SUPERFAMILY SSF52540 27 586 1.22E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:3.30.190.20 147 261 3.9E-251 T 13-10-2018 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:1.20.1580.10 707 845 5.3E-141 T 13-10-2018 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:3.40.50.300 22 611 3.9E-251 T 13-10-2018 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 SUPERFAMILY SSF52540 630 928 1.55E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:1.10.8.280 304 420 3.9E-251 T 13-10-2018 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 ProSitePatterns PS00211 ABC transporters family signature. 845 859 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:1.20.1580.10 107 509 3.9E-251 T 13-10-2018 Spica_1225 f7dc23f64ed290f4e111bda8b417f539 961 Gene3D G3DSA:3.40.50.300 632 950 5.3E-141 T 13-10-2018 Spica_0736 fb9ede9853ed5ed83d17acfe2cfd137b 428 Pfam PF13416 Bacterial extracellular solute-binding protein 55 367 7.5E-32 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0736 fb9ede9853ed5ed83d17acfe2cfd137b 428 Gene3D G3DSA:3.40.190.10 158 410 1.7E-66 T 13-10-2018 Spica_0736 fb9ede9853ed5ed83d17acfe2cfd137b 428 SUPERFAMILY SSF53850 23 425 3.71E-70 T 13-10-2018 Spica_0736 fb9ede9853ed5ed83d17acfe2cfd137b 428 Gene3D G3DSA:3.40.190.10 64 384 1.7E-66 T 13-10-2018 Spica_2087 609b658bb7dcb84fd1a1b1c128319482 279 SUPERFAMILY SSF52518 9 271 4.76E-87 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2087 609b658bb7dcb84fd1a1b1c128319482 279 Gene3D G3DSA:3.40.50.970 1 277 1.4E-95 T 13-10-2018 Spica_2087 609b658bb7dcb84fd1a1b1c128319482 279 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 12 267 1.1E-55 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 Gene3D G3DSA:3.40.1550.10 45 231 4.6E-67 T 13-10-2018 IPR028976 CheC-like superfamily Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 8.1E-118 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 SUPERFAMILY SSF103039 45 230 6.19E-30 T 13-10-2018 IPR028976 CheC-like superfamily Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 Gene3D G3DSA:2.30.330.10 240 333 1.3E-7 T 13-10-2018 IPR036429 SpoA-like superfamily Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 6.6E-33 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 6.6E-33 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 6.6E-33 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 6.6E-33 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 SUPERFAMILY SSF101801 250 324 9.42E-15 T 13-10-2018 IPR036429 SpoA-like superfamily Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 Pfam PF02154 Flagellar motor switch protein FliM 39 229 2.3E-83 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 323 1.3E-21 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) Spica_1532 1bf322835de1318b2b62f55f495ab23b 343 PIRSF PIRSF002888 1 334 1.4E-116 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Spica_1617 83d40dfa581ad973c653d5fddf261bbb 247 SUPERFAMILY SSF69593 12 245 1.96E-42 T 13-10-2018 Spica_1617 83d40dfa581ad973c653d5fddf261bbb 247 Pfam PF01553 Acyltransferase 66 191 1.4E-26 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_1617 83d40dfa581ad973c653d5fddf261bbb 247 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 63 191 4.3E-33 T 13-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 Spica_1617 83d40dfa581ad973c653d5fddf261bbb 247 SMART SM00563 80 194 1.3E-26 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_0698 a293d05f3aa5ada256bdc5e076c66d0d 199 Pfam PF12822 ECF transporter, substrate-specific component 7 179 6.3E-19 T 13-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 Spica_0698 a293d05f3aa5ada256bdc5e076c66d0d 199 Gene3D G3DSA:1.10.1760.20 5 190 5.7E-43 T 13-10-2018 Spica_2169 4027d67885feac7d922d360574601bc4 866 SUPERFAMILY SSF81665 15 864 4.71E-92 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 SMART SM00831 14 87 2.5E-9 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 557 682 1.2E-27 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 370 5.6E-23 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 Gene3D G3DSA:3.40.50.1000 505 614 5.0E-5 T 13-10-2018 IPR023214 HAD superfamily Spica_2169 4027d67885feac7d922d360574601bc4 866 Gene3D G3DSA:1.20.1110.10 216 346 3.9E-26 T 13-10-2018 Spica_2169 4027d67885feac7d922d360574601bc4 866 Pfam PF00122 E1-E2 ATPase 124 314 1.8E-46 T 13-10-2018 Spica_2169 4027d67885feac7d922d360574601bc4 866 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 22 864 0.0 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 SUPERFAMILY SSF81653 126 232 1.83E-29 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 Pfam PF00690 Cation transporter/ATPase, N-terminus 21 82 9.0E-13 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 SUPERFAMILY SSF56784 332 695 2.88E-40 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2169 4027d67885feac7d922d360574601bc4 866 Gene3D G3DSA:2.70.150.10 102 215 1.3E-29 T 13-10-2018 Spica_2169 4027d67885feac7d922d360574601bc4 866 Pfam PF00689 Cation transporting ATPase, C-terminus 679 850 3.5E-12 T 13-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 724 740 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 654 669 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 247 263 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 770 791 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 264 283 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 704 717 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 368 381 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 672 683 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 PRINTS PR01836 Magnesium-transporting ATPase signature 820 841 5.6E-65 T 13-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 Spica_2169 4027d67885feac7d922d360574601bc4 866 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 610 3.6E-19 T 13-10-2018 Spica_2169 4027d67885feac7d922d360574601bc4 866 Gene3D G3DSA:3.40.1110.10 347 504 3.5E-54 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Spica_2169 4027d67885feac7d922d360574601bc4 866 Gene3D G3DSA:1.20.1110.10 615 865 1.3E-25 T 13-10-2018 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 SUPERFAMILY SSF53822 62 328 8.7E-63 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 13-10-2018 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 Gene3D G3DSA:1.10.260.40 1 54 1.5E-21 T 13-10-2018 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 Pfam PF13377 Periplasmic binding protein-like domain 169 329 1.3E-30 T 13-10-2018 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 SUPERFAMILY SSF47413 1 59 7.21E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 SMART SM00354 1 71 9.0E-25 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.9E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 Gene3D G3DSA:3.40.50.2300 159 289 3.8E-61 T 13-10-2018 Spica_0624 8b00a5646ec3f77cbb9e690284ef570a 329 Gene3D G3DSA:3.40.50.2300 55 305 3.8E-61 T 13-10-2018 Spica_2010 bd83565a8653d20b7bde23e769706dcb 343 Gene3D G3DSA:3.40.50.2300 35 311 3.5E-91 T 13-10-2018 Spica_2010 bd83565a8653d20b7bde23e769706dcb 343 SUPERFAMILY SSF53822 34 321 3.08E-55 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2010 bd83565a8653d20b7bde23e769706dcb 343 Pfam PF13407 Periplasmic binding protein domain 44 292 1.8E-47 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2010 bd83565a8653d20b7bde23e769706dcb 343 Gene3D G3DSA:3.40.50.2300 136 331 3.5E-91 T 13-10-2018 Spica_2787 eff93e4fdd4bbee769b4f03bad61feab 252 SUPERFAMILY SSF52540 1 250 3.43E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2787 eff93e4fdd4bbee769b4f03bad61feab 252 Pfam PF13614 AAA domain 3 176 1.5E-61 T 13-10-2018 IPR025669 AAA domain Spica_2787 eff93e4fdd4bbee769b4f03bad61feab 252 Gene3D G3DSA:3.40.50.300 1 251 1.8E-80 T 13-10-2018 Spica_2787 eff93e4fdd4bbee769b4f03bad61feab 252 PIRSF PIRSF009320 89 252 5.8E-6 T 13-10-2018 Spica_2787 eff93e4fdd4bbee769b4f03bad61feab 252 PIRSF PIRSF009320 2 78 3.6E-15 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Pfam PF00391 PEP-utilising enzyme, mobile domain 427 506 4.6E-26 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 881 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 302 3.4E-48 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 305 361 1.3E-11 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 SUPERFAMILY SSF56059 3 384 3.3E-144 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 772 790 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:3.20.20.60 545 884 1.0E-144 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:1.10.189.10 350 531 2.1E-78 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:1.20.80.30 116 203 9.6E-110 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 SUPERFAMILY SSF51621 542 880 9.42E-120 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 SUPERFAMILY SSF52009 396 515 1.31E-35 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:3.30.470.20 249 346 3.7E-40 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 543 880 3.8E-86 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 455 466 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:3.30.1490.20 16 248 9.6E-110 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 Gene3D G3DSA:3.50.30.10 388 508 2.1E-78 T 13-10-2018 Spica_1304 c690f94d582f20ebdb8e3b072f5dd4a0 887 PIRSF PIRSF000853 3 887 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_2067 f64dcc7cb0c4ba5266062cc20b0cae44 726 Pfam PF13200 Putative glycosyl hydrolase domain 382 702 1.1E-79 T 13-10-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 Spica_2067 f64dcc7cb0c4ba5266062cc20b0cae44 726 SUPERFAMILY SSF51445 444 655 7.86E-7 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2067 f64dcc7cb0c4ba5266062cc20b0cae44 726 Gene3D G3DSA:2.130.10.10 31 245 1.4E-6 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_2067 f64dcc7cb0c4ba5266062cc20b0cae44 726 SUPERFAMILY SSF110296 67 184 7.85E-7 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 SUPERFAMILY SSF53850 377 556 9.34E-53 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Gene3D G3DSA:3.40.190.10 369 460 1.0E-25 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Pfam PF00793 DAHP synthetase I family 87 321 1.8E-74 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Gene3D G3DSA:3.40.190.10 461 542 4.2E-27 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 SUPERFAMILY SSF51569 1 334 9.16E-105 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Pfam PF01842 ACT domain 586 637 1.2E-6 T 13-10-2018 IPR002912 ACT domain Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Gene3D G3DSA:3.30.70.260 578 665 3.1E-24 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Pfam PF00800 Prephenate dehydratase 377 556 1.8E-58 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 70 326 3.7E-115 T 13-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 612 619 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Gene3D G3DSA:3.30.70.1140 1 74 6.5E-10 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 SUPERFAMILY SSF55021 577 663 2.33E-22 T 13-10-2018 Spica_2678 a2563076147d0ca34802dcf64dd92797 666 Gene3D G3DSA:3.20.20.70 75 331 1.9E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 54 61 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 Gene3D G3DSA:3.40.50.1370 139 308 1.3E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 125 139 1.3E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 1.3E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 52 66 1.3E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 85 98 1.3E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 1.3E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 149 3.6E-49 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 310 5.8E-56 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 Gene3D G3DSA:3.40.50.1370 9 138 1.3E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 8 313 76.21 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 SUPERFAMILY SSF53671 6 312 2.23E-99 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 3.0E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 3.0E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 3.0E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 54 73 3.0E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_1102 71264dddf1a9f2d07e67c9625da5f37a 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 312 7.9E-127 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 217 253 1.9E-15 T 13-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 Gene3D G3DSA:2.10.240.10 217 254 9.7E-13 T 13-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 Gene3D G3DSA:3.40.50.80 115 216 1.7E-13 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 PIRSF PIRSF006816 16 257 7.3E-50 T 13-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 Gene3D G3DSA:2.40.30.10 15 107 1.6E-14 T 13-10-2018 Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 SUPERFAMILY SSF52343 104 254 1.96E-22 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 PRINTS PR00409 Phthalate dioxygenase reductase family signature 120 139 7.7E-5 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 PRINTS PR00409 Phthalate dioxygenase reductase family signature 190 198 7.7E-5 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Spica_2553 4cbc0c2de0b2a702a011cc1a8dafbd01 257 SUPERFAMILY SSF63380 43 108 1.11E-13 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Spica_0261 4107d6c151f6e866aadde492bde3c531 141 Pfam PF13470 PIN domain 4 117 8.9E-10 T 13-10-2018 IPR002716 PIN domain Spica_0261 4107d6c151f6e866aadde492bde3c531 141 SUPERFAMILY SSF88723 1 133 1.83E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 SUPERFAMILY SSF49493 264 349 1.44E-22 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Pfam PF01556 DnaJ C terminal domain 127 338 9.0E-42 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 39.56 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Gene3D G3DSA:2.10.230.10 153 213 4.8E-36 T 13-10-2018 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 SMART SM00271 4 62 3.1E-33 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 PRINTS PR00625 DnaJ domain signature 25 40 2.9E-32 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 PRINTS PR00625 DnaJ domain signature 7 25 2.9E-32 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 PRINTS PR00625 DnaJ domain signature 42 62 2.9E-32 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 PRINTS PR00625 DnaJ domain signature 62 81 2.9E-32 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 SUPERFAMILY SSF57938 140 217 2.75E-19 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Gene3D G3DSA:2.60.260.20 123 255 4.8E-36 T 13-10-2018 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Pfam PF00684 DnaJ central domain 153 213 2.8E-11 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Gene3D G3DSA:1.10.287.110 1 116 5.4E-37 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 354 3.4E-131 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Gene3D G3DSA:2.60.260.20 260 361 1.8E-30 T 13-10-2018 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 SUPERFAMILY SSF46565 2 110 2.49E-36 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 SUPERFAMILY SSF49493 121 273 7.33E-21 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 Pfam PF00226 DnaJ domain 5 67 6.6E-29 T 13-10-2018 IPR001623 DnaJ domain Spica_2739 906b02bc3d4482a40fd9ad9c350c2caf 373 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-10-2018 IPR018253 DnaJ domain, conserved site Spica_2419 b402a9db682a252642f75d2cee74f86f 195 SUPERFAMILY SSF48498 76 186 4.45E-12 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_2419 b402a9db682a252642f75d2cee74f86f 195 Pfam PF13305 WHG domain 76 159 3.0E-12 T 13-10-2018 IPR025996 WHG domain Spica_2419 b402a9db682a252642f75d2cee74f86f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 7.1E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2419 b402a9db682a252642f75d2cee74f86f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 7.1E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2419 b402a9db682a252642f75d2cee74f86f 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 45 3.2E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2419 b402a9db682a252642f75d2cee74f86f 195 Gene3D G3DSA:1.10.357.10 1 188 4.2E-41 T 13-10-2018 Spica_2419 b402a9db682a252642f75d2cee74f86f 195 SUPERFAMILY SSF46689 1 64 2.98E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2419 b402a9db682a252642f75d2cee74f86f 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 44 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 Pfam PF04055 Radical SAM superfamily 78 235 1.6E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 PIRSF PIRSF005963 7 316 1.6E-120 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 TIGRFAM TIGR00510 lipA: lipoyl synthase 20 302 4.8E-98 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 23 60 6.7E-8 T 13-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 SMART SM00729 71 277 1.1E-12 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 SUPERFAMILY SSF102114 36 296 4.05E-55 T 13-10-2018 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 Gene3D G3DSA:3.20.20.70 71 257 3.9E-19 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1729 5420395f24ad387c9fcbc5c3eee3fcd6 319 Hamap MF_00206 Lipoyl synthase [lipA]. 1 308 116.407 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 Pfam PF05191 Adenylate kinase, active site lid 122 157 6.2E-18 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 TIGRFAM TIGR01351 adk: adenylate kinase 2 207 2.8E-76 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 Pfam PF00406 Adenylate kinase 6 185 3.9E-50 T 13-10-2018 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 SUPERFAMILY SSF52540 1 201 4.89E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 Hamap MF_00235 Adenylate kinase [adk]. 1 208 48.027 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 Gene3D G3DSA:3.40.50.300 1 209 4.5E-79 T 13-10-2018 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 PRINTS PR00094 Adenylate kinase signature 32 46 6.5E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 PRINTS PR00094 Adenylate kinase signature 81 97 6.5E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 PRINTS PR00094 Adenylate kinase signature 172 186 6.5E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 PRINTS PR00094 Adenylate kinase signature 4 17 6.5E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_1979 09c0159faaa22b741eb2f31cd374e0d1 209 PRINTS PR00094 Adenylate kinase signature 155 170 6.5E-33 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Gene3D G3DSA:3.40.50.300 2 181 2.6E-34 T 13-10-2018 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Gene3D G3DSA:3.40.50.300 302 455 1.4E-34 T 13-10-2018 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 SUPERFAMILY SSF52980 1004 1152 6.97E-12 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Gene3D G3DSA:3.40.50.300 704 909 1.1E-24 T 13-10-2018 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1000 1137 4.1E-8 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 SUPERFAMILY SSF52540 8 846 2.05E-100 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Gene3D G3DSA:3.40.50.300 518 615 5.4E-18 T 13-10-2018 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Gene3D G3DSA:3.90.320.10 960 1156 5.0E-17 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 421 2.4E-57 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Spica_0063 ef47f40e6ec4af34a5acdfe275d821e3 1177 Pfam PF13361 UvrD-like helicase C-terminal domain 437 844 4.3E-28 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spica_1605 ce76443b3ad7e4ca3f0836f72ed12d6b 159 Pfam PF02464 Competence-damaged protein 4 156 7.9E-49 T 13-10-2018 IPR008136 CinA, C-terminal Spica_1605 ce76443b3ad7e4ca3f0836f72ed12d6b 159 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 10 155 3.9E-41 T 13-10-2018 IPR008136 CinA, C-terminal Spica_1605 ce76443b3ad7e4ca3f0836f72ed12d6b 159 Gene3D G3DSA:3.90.950.20 1 158 7.2E-53 T 13-10-2018 IPR036653 CinA-like, C-terminal Spica_1605 ce76443b3ad7e4ca3f0836f72ed12d6b 159 SUPERFAMILY SSF142433 4 157 1.7E-46 T 13-10-2018 IPR036653 CinA-like, C-terminal Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 468 587 6.8E-24 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 225 344 2.0E-9 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 Gene3D G3DSA:3.40.50.300 408 606 1.9E-35 T 13-10-2018 Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 Gene3D G3DSA:3.40.50.300 201 369 1.8E-16 T 13-10-2018 Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 SMART SM00382 221 348 2.3E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 SMART SM00382 464 591 8.2E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 SUPERFAMILY SSF52540 442 612 3.0E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2794 ece1014c59ce00af6cbb138fc859b275 667 SUPERFAMILY SSF52540 214 416 2.19E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 Pfam PF01960 ArgJ family 16 408 1.6E-151 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 31 408 2.0E-103 T 13-10-2018 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 4 408 1.2E-148 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 152.539 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 Gene3D G3DSA:3.30.2330.10 190 274 1.8E-32 T 13-10-2018 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 SUPERFAMILY SSF56266 11 405 1.48E-131 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 Gene3D G3DSA:3.10.20.340 275 408 2.8E-44 T 13-10-2018 Spica_0884 cf19d2260e5befd4e2e17676ecd96a3f 408 Gene3D G3DSA:3.60.70.12 1 189 2.8E-67 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Gene3D G3DSA:3.30.420.40 208 255 6.2E-27 T 13-10-2018 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 SUPERFAMILY SSF53067 84 364 5.32E-28 T 13-10-2018 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Gene3D G3DSA:1.10.10.10 12 80 9.6E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Gene3D G3DSA:3.30.420.40 88 207 6.2E-27 T 13-10-2018 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Gene3D G3DSA:3.30.420.40 279 364 2.2E-6 T 13-10-2018 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 59 7.8E-8 T 13-10-2018 Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 SUPERFAMILY SSF46785 12 76 1.3E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0352 bc07dd4b8d21ad633e1796419f7a9bcf 388 Pfam PF00480 ROK family 87 255 2.0E-16 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_1115 4df6321aaf00ff651272bf940c93df24 625 SUPERFAMILY SSF64518 164 622 3.01E-24 T 13-10-2018 Spica_1115 4df6321aaf00ff651272bf940c93df24 625 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 8 338 3.4E-76 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Spica_1115 4df6321aaf00ff651272bf940c93df24 625 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 575 621 3.4E-12 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1115 4df6321aaf00ff651272bf940c93df24 625 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 2.0E-5 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Spica_1115 4df6321aaf00ff651272bf940c93df24 625 PRINTS PR01005 Flagellar hook-associated protein signature 134 154 2.0E-5 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Spica_1115 4df6321aaf00ff651272bf940c93df24 625 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 2.0E-5 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 634 1.5E-19 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 SMART SM00663 224 503 5.9E-170 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:1.10.40.90 363 405 8.2E-18 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF00623 RNA polymerase Rpb1, domain 2 383 474 1.2E-25 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 378 3.8E-8 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:1.10.150.390 1330 1392 7.7E-28 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:1.10.132.30 631 769 8.1E-65 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:2.40.50.100 1050 1141 2.1E-23 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 2.4E-90 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1391 18.92 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF05000 RNA polymerase Rpb1, domain 4 663 735 8.9E-17 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 SUPERFAMILY SSF64484 6 1381 0.0 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:1.10.274.100 479 630 4.5E-36 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:2.40.50.100 1166 1229 9.3E-64 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Pfam PF04998 RNA polymerase Rpb1, domain 5 745 1330 9.6E-74 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 Gene3D G3DSA:1.10.1790.20 1150 1328 9.3E-64 T 13-10-2018 Spica_0380 1c40be7ce7b3dd99433fc5275715cd10 1424 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1381 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 ProSitePatterns PS00164 Enolase signature. 338 351 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 Pfam PF03952 Enolase, N-terminal domain 4 134 5.2E-64 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 SMART SM01193 4 134 7.5E-101 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 SMART SM01192 139 429 1.5E-209 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 315 326 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 107 123 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 161 174 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 367 384 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 37 51 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PRINTS PR00148 Enolase signature 338 352 2.7E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 Gene3D G3DSA:3.20.20.120 128 432 1.6E-133 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Spica_0549 54fc5f6279860f3fc546742719172fc6 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 2.0E-128 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 PIRSF PIRSF001400 1 429 1.1E-192 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 Gene3D G3DSA:3.30.390.10 1 126 1.0E-58 T 13-10-2018 IPR029017 Enolase-like, N-terminal Spica_0549 54fc5f6279860f3fc546742719172fc6 432 SUPERFAMILY SSF54826 3 138 3.21E-59 T 13-10-2018 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 3.0E-213 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 Hamap MF_00318 Enolase [eno]. 2 415 44.74 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0549 54fc5f6279860f3fc546742719172fc6 432 SUPERFAMILY SSF51604 140 429 4.1E-124 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Spica_1970 fa665a0348d62d853e72577d17481171 716 SUPERFAMILY SSF64182 52 210 3.4E-48 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_1970 fa665a0348d62d853e72577d17481171 716 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 704 3.4E-176 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 Spica_1970 fa665a0348d62d853e72577d17481171 716 Pfam PF02272 DHHA1 domain 456 576 2.3E-19 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Spica_1970 fa665a0348d62d853e72577d17481171 716 Pfam PF01368 DHH family 78 208 1.8E-11 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_1970 fa665a0348d62d853e72577d17481171 716 SUPERFAMILY SSF64182 355 580 1.45E-48 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_1970 fa665a0348d62d853e72577d17481171 716 Gene3D G3DSA:3.90.1640.30 52 233 1.8E-50 T 13-10-2018 Spica_1970 fa665a0348d62d853e72577d17481171 716 Gene3D G3DSA:3.90.1640.30 318 458 4.9E-28 T 13-10-2018 Spica_1970 fa665a0348d62d853e72577d17481171 716 Gene3D G3DSA:3.10.310.30 461 583 5.7E-25 T 13-10-2018 Spica_0642 549b869848707df4411632f7ac34ce60 236 Pfam PF03266 NTPase 52 185 1.3E-7 T 13-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Spica_0642 549b869848707df4411632f7ac34ce60 236 Gene3D G3DSA:3.40.50.300 50 232 4.4E-8 T 13-10-2018 Spica_0642 549b869848707df4411632f7ac34ce60 236 SUPERFAMILY SSF52540 52 189 2.23E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 Gene3D G3DSA:1.10.443.10 111 289 5.9E-62 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 SUPERFAMILY SSF47823 10 100 3.53E-12 T 13-10-2018 Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 295 47.693 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 90 2.3E-11 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 Pfam PF00589 Phage integrase family 111 280 5.5E-43 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 Gene3D G3DSA:1.10.150.130 4 98 1.9E-14 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Spica_1680 4682aba2e22da043d0c7e52afffc7e34 300 SUPERFAMILY SSF56349 106 290 2.09E-52 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spica_0591 c1a7442c4729fba41f0367c5107ec352 208 Pfam PF01497 Periplasmic binding protein 119 205 5.3E-9 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain Spica_0591 c1a7442c4729fba41f0367c5107ec352 208 SUPERFAMILY SSF53807 53 205 5.1E-21 T 13-10-2018 Spica_0591 c1a7442c4729fba41f0367c5107ec352 208 Gene3D G3DSA:3.40.50.1980 52 184 9.4E-37 T 13-10-2018 Spica_2157 fa855817e5efaa7974fd425c5a13714d 330 SUPERFAMILY SSF103481 96 178 5.36E-9 T 13-10-2018 Spica_2157 fa855817e5efaa7974fd425c5a13714d 330 SUPERFAMILY SSF103481 222 319 1.02E-8 T 13-10-2018 Spica_2157 fa855817e5efaa7974fd425c5a13714d 330 Pfam PF00892 EamA-like transporter family 101 174 3.4E-6 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_2157 fa855817e5efaa7974fd425c5a13714d 330 Pfam PF00892 EamA-like transporter family 184 315 3.0E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_2157 fa855817e5efaa7974fd425c5a13714d 330 Pfam PF00892 EamA-like transporter family 7 62 1.8E-8 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_2669 ff8060a42c078aad60ab027ff726c4f2 314 SUPERFAMILY SSF56784 13 281 1.74E-24 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2669 ff8060a42c078aad60ab027ff726c4f2 314 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 244 7.3E-17 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 Spica_2669 ff8060a42c078aad60ab027ff726c4f2 314 Gene3D G3DSA:3.40.50.1000 12 141 1.9E-10 T 13-10-2018 IPR023214 HAD superfamily Spica_2669 ff8060a42c078aad60ab027ff726c4f2 314 Gene3D G3DSA:3.40.50.1000 161 287 2.3E-8 T 13-10-2018 IPR023214 HAD superfamily Spica_2669 ff8060a42c078aad60ab027ff726c4f2 314 Pfam PF08282 haloacid dehalogenase-like hydrolase 18 89 1.0E-6 T 13-10-2018 Spica_1745 335ca2847cf2c11ce6d9ed31f8aae88e 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 50 3.0E-7 T 13-10-2018 Spica_1745 335ca2847cf2c11ce6d9ed31f8aae88e 93 Gene3D G3DSA:3.40.1620.10 6 45 1.0E-7 T 13-10-2018 Spica_1745 335ca2847cf2c11ce6d9ed31f8aae88e 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 63 5.4E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_1745 335ca2847cf2c11ce6d9ed31f8aae88e 93 SUPERFAMILY SSF143120 7 80 5.32E-15 T 13-10-2018 IPR036165 YefM-like superfamily Spica_1787 335ca2847cf2c11ce6d9ed31f8aae88e 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 50 3.0E-7 T 13-10-2018 Spica_1787 335ca2847cf2c11ce6d9ed31f8aae88e 93 Gene3D G3DSA:3.40.1620.10 6 45 1.0E-7 T 13-10-2018 Spica_1787 335ca2847cf2c11ce6d9ed31f8aae88e 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 63 5.4E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_1787 335ca2847cf2c11ce6d9ed31f8aae88e 93 SUPERFAMILY SSF143120 7 80 5.32E-15 T 13-10-2018 IPR036165 YefM-like superfamily Spica_1765 335ca2847cf2c11ce6d9ed31f8aae88e 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 50 3.0E-7 T 13-10-2018 Spica_1765 335ca2847cf2c11ce6d9ed31f8aae88e 93 Gene3D G3DSA:3.40.1620.10 6 45 1.0E-7 T 13-10-2018 Spica_1765 335ca2847cf2c11ce6d9ed31f8aae88e 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 63 5.4E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_1765 335ca2847cf2c11ce6d9ed31f8aae88e 93 SUPERFAMILY SSF143120 7 80 5.32E-15 T 13-10-2018 IPR036165 YefM-like superfamily Spica_1754 335ca2847cf2c11ce6d9ed31f8aae88e 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 11 50 3.0E-7 T 13-10-2018 Spica_1754 335ca2847cf2c11ce6d9ed31f8aae88e 93 Gene3D G3DSA:3.40.1620.10 6 45 1.0E-7 T 13-10-2018 Spica_1754 335ca2847cf2c11ce6d9ed31f8aae88e 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 63 5.4E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_1754 335ca2847cf2c11ce6d9ed31f8aae88e 93 SUPERFAMILY SSF143120 7 80 5.32E-15 T 13-10-2018 IPR036165 YefM-like superfamily Spica_1895 8b1fa0942ae47dfc3d06d2082923c819 433 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 136 153 - T 13-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 Spica_1895 8b1fa0942ae47dfc3d06d2082923c819 433 SUPERFAMILY SSF53850 21 419 5.18E-74 T 13-10-2018 Spica_1895 8b1fa0942ae47dfc3d06d2082923c819 433 Gene3D G3DSA:3.40.190.10 25 379 1.6E-141 T 13-10-2018 Spica_1895 8b1fa0942ae47dfc3d06d2082923c819 433 Gene3D G3DSA:3.40.190.10 141 419 1.6E-141 T 13-10-2018 Spica_1895 8b1fa0942ae47dfc3d06d2082923c819 433 Pfam PF13416 Bacterial extracellular solute-binding protein 40 353 1.9E-42 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 2.4E-12 T 13-10-2018 IPR004176 Clp, N-terminal Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 1.5E-11 T 13-10-2018 IPR004176 Clp, N-terminal Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Gene3D G3DSA:1.10.1780.10 1 148 2.1E-34 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 2.3E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 2.3E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 2.3E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 2.3E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 3.0E-29 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Gene3D G3DSA:3.40.50.300 553 765 1.0E-86 T 13-10-2018 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Gene3D G3DSA:1.10.8.60 766 855 1.1E-30 T 13-10-2018 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Gene3D G3DSA:3.40.50.300 149 342 2.7E-77 T 13-10-2018 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SMART SM01086 766 855 4.1E-41 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SUPERFAMILY SSF52540 159 548 5.34E-97 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SMART SM00382 198 343 5.5E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SMART SM00382 600 743 1.5E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 3.7E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 759 1.6E-55 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 Gene3D G3DSA:3.40.50.300 343 547 1.4E-71 T 13-10-2018 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SUPERFAMILY SSF81923 4 156 5.36E-40 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_1844 a2c2eede76b70a3f7151a2dc3ded9638 856 SUPERFAMILY SSF52540 549 852 3.91E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 SMART SM00347 26 126 5.1E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 Gene3D G3DSA:1.10.10.10 3 138 1.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 SUPERFAMILY SSF46785 5 139 2.53E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1023 8ed9e1d111d779213623a59b9dd0fd28 150 Pfam PF13463 Winged helix DNA-binding domain 42 99 6.6E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 463 474 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 SUPERFAMILY SSF52016 375 554 3.61E-63 T 13-10-2018 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 Pfam PF00920 Dehydratase family 31 552 4.8E-225 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 555 46.823 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 555 3.2E-232 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 Gene3D G3DSA:3.50.30.80 375 526 4.1E-57 T 13-10-2018 Spica_2672 740a348db009695ad7e68ca4bb55e400 556 SUPERFAMILY SSF143975 1 374 7.98E-135 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_1544 1011d6f9d2ea392240f2fa516c5d86dd 121 SMART SM00347 21 119 2.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1544 1011d6f9d2ea392240f2fa516c5d86dd 121 SUPERFAMILY SSF46785 6 101 6.08E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1544 1011d6f9d2ea392240f2fa516c5d86dd 121 Pfam PF12802 MarR family 28 83 8.0E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1544 1011d6f9d2ea392240f2fa516c5d86dd 121 Gene3D G3DSA:1.10.10.10 1 106 1.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0882 5c1661a20f763c44698f1809f0a1b938 132 SUPERFAMILY SSF48452 36 103 4.75E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0882 5c1661a20f763c44698f1809f0a1b938 132 Gene3D G3DSA:1.25.40.10 31 119 5.7E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Gene3D G3DSA:3.30.830.10 2 257 1.9E-77 T 13-10-2018 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Pfam PF08367 Peptidase M16C associated 471 732 2.0E-50 T 13-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 SUPERFAMILY SSF63411 811 978 1.47E-18 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 SMART SM01264 470 732 2.2E-64 T 13-10-2018 IPR013578 Peptidase M16C associated GO:0006508 Reactome: R-HSA-1268020 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Pfam PF00675 Insulinase (Peptidase family M16) 63 147 4.3E-6 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Pfam PF05193 Peptidase M16 inactive domain 213 391 2.4E-18 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Spica_1959 127710fdf20b54bcd5189d910c28365e 997 SUPERFAMILY SSF63411 531 786 5.4E-44 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Gene3D G3DSA:3.30.830.10 542 789 3.1E-63 T 13-10-2018 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Gene3D G3DSA:3.30.830.10 494 541 4.0E-6 T 13-10-2018 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Gene3D G3DSA:3.30.830.10 791 990 1.6E-37 T 13-10-2018 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 Gene3D G3DSA:3.30.830.10 262 491 1.1E-64 T 13-10-2018 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 SUPERFAMILY SSF63411 268 527 5.33E-51 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_1959 127710fdf20b54bcd5189d910c28365e 997 SUPERFAMILY SSF63411 10 262 1.28E-42 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 575 40.608 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 SUPERFAMILY SSF53927 202 260 4.51E-13 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Gene3D G3DSA:3.40.140.20 437 575 1.9E-53 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 SMART SM00851 14 128 3.4E-52 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Gene3D G3DSA:3.40.50.1380 1 196 3.8E-83 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 SMART SM00798 133 506 1.8E-162 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Gene3D G3DSA:3.40.140.20 199 268 2.1E-13 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 PIRSF PIRSF000414 1 265 9.2E-92 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 PIRSF PIRSF000414 307 575 9.8E-99 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 257 2.7E-38 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Pfam PF01808 AICARFT/IMPCHase bienzyme 322 505 4.8E-64 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Gene3D G3DSA:3.40.140.20 312 421 5.3E-36 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 Pfam PF02142 MGS-like domain 14 128 7.3E-24 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 SUPERFAMILY SSF53927 327 575 1.6E-95 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Spica_2417 f0b221f98cebc16cdbc3432782453aaa 575 SUPERFAMILY SSF52335 2 190 2.49E-64 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 Pfam PF00023 Ankyrin repeat 241 273 0.011 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 Pfam PF12796 Ankyrin repeats (3 copies) 150 238 6.0E-10 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 Gene3D G3DSA:1.25.40.20 130 295 2.3E-37 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 SMART SM00248 208 237 0.04 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 SMART SM00248 241 270 5.9E-4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 SMART SM00248 174 203 0.1 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 Spica_1514 08e8d5702b8a9b73d82003b5d2a4cc3b 296 SUPERFAMILY SSF48403 149 294 7.93E-33 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 Gene3D G3DSA:3.40.1190.20 258 627 6.3E-54 T 13-10-2018 IPR029056 Ribokinase-like Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 Gene3D G3DSA:3.40.50.150 70 245 2.8E-15 T 13-10-2018 Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 Pfam PF00294 pfkB family carbohydrate kinase 261 608 3.3E-21 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 SUPERFAMILY SSF53613 260 607 8.57E-31 T 13-10-2018 IPR029056 Ribokinase-like Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 Pfam PF13489 Methyltransferase domain 86 233 2.0E-17 T 13-10-2018 Spica_1543 cc8f5b5a0d551b42d00aa3bcc1108d32 635 SUPERFAMILY SSF53335 84 243 1.03E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2026 e31c822ab74262eac30abbe0226edd10 387 Gene3D G3DSA:2.40.50.140 274 355 2.8E-22 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 297 316 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 115 131 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 133 150 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 48 62 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 30 48 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 162 182 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 337 355 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 PRINTS PR00681 Ribosomal protein S1 signature 219 240 2.2E-35 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SUPERFAMILY SSF50249 26 119 3.27E-11 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2026 e31c822ab74262eac30abbe0226edd10 387 Pfam PF00575 S1 RNA binding domain 197 267 1.5E-20 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 Pfam PF00575 S1 RNA binding domain 282 351 8.5E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SUPERFAMILY SSF50249 197 284 3.29E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2026 e31c822ab74262eac30abbe0226edd10 387 Gene3D G3DSA:2.40.50.140 14 107 2.4E-11 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 Gene3D G3DSA:2.40.50.140 194 273 3.5E-25 T 13-10-2018 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SMART SM00316 110 178 1.6 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SMART SM00316 282 354 1.3E-16 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SMART SM00316 28 94 6.6E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SMART SM00316 197 267 2.7E-23 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SUPERFAMILY SSF50249 114 191 1.95E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2026 e31c822ab74262eac30abbe0226edd10 387 SUPERFAMILY SSF50249 262 357 3.86E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 SUPERFAMILY SSF48452 473 611 2.61E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 Gene3D G3DSA:1.25.40.10 471 959 1.2E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 SUPERFAMILY SSF48452 693 894 5.01E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 SMART SM00028 861 894 28.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 SMART SM00028 701 734 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2060 a22e5c3d3bf5b9e2edd53198d9ad14d4 1011 SMART SM00028 827 860 31.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Gene3D G3DSA:1.10.238.260 280 394 3.7E-38 T 13-10-2018 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 497 5.5E-220 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 499 1.2E-32 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 SMART SM00917 369 500 3.3E-32 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Gene3D G3DSA:3.20.20.70 2 276 5.8E-113 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 SUPERFAMILY SSF110921 412 498 3.14E-21 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 43.047 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Gene3D G3DSA:3.30.160.270 395 500 1.1E-8 T 13-10-2018 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 SUPERFAMILY SSF51569 2 291 1.04E-100 T 13-10-2018 Spica_2675 12091ac6236a6dc2fc87b96c64b1607d 520 Pfam PF00682 HMGL-like 5 273 2.0E-96 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 167 174 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 SMART SM00846 1 169 4.2E-77 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 115 1.3E-30 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 Gene3D G3DSA:3.30.360.10 170 340 1.1E-150 T 13-10-2018 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 174 336 7.7E-64 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 288 303 2.0E-44 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 248 265 2.0E-44 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 163 181 2.0E-44 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 121 134 2.0E-44 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 191 207 2.0E-44 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 SUPERFAMILY SSF55347 168 336 8.11E-72 T 13-10-2018 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 2 347 6.8E-128 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 PIRSF PIRSF000149 1 356 6.9E-128 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 SUPERFAMILY SSF51735 2 191 2.04E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1827 1b2f1e0c34a9c170004d1f9a1ae390c8 356 Gene3D G3DSA:3.40.50.720 2 353 1.1E-150 T 13-10-2018 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 SUPERFAMILY SSF48239 1386 1629 4.71E-34 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Gene3D G3DSA:1.50.10.20 1383 1635 1.8E-27 T 13-10-2018 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 980 1121 7.9E-12 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 SMART SM01360 1185 1274 1.9E-17 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1391 1411 4.0E-5 T 13-10-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Pfam PF00207 Alpha-2-macroglobulin family 1189 1273 1.7E-11 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 513 608 6.2E-13 T 13-10-2018 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 SMART SM01359 980 1122 1.7E-25 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 Spica_2336 199fbf93ea0ac7048ed4d1558c643ece 1865 Pfam PF01835 MG2 domain 614 696 4.8E-12 T 13-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 SMART SM00116 115 163 8.3 T 13-10-2018 IPR000644 CBS domain Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 SMART SM00116 53 102 0.1 T 13-10-2018 IPR000644 CBS domain Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 SUPERFAMILY SSF54631 39 182 1.12E-33 T 13-10-2018 Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 SUPERFAMILY SSF56176 175 257 4.09E-22 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 Gene3D G3DSA:3.10.580.10 23 172 3.5E-56 T 13-10-2018 Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 SMART SM01091 178 256 4.8E-27 T 13-10-2018 IPR005170 Transporter-associated domain Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 Gene3D G3DSA:3.30.465.10 173 253 9.7E-23 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 Pfam PF03471 Transporter associated domain 179 254 5.9E-22 T 13-10-2018 IPR005170 Transporter-associated domain Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 Pfam PF00571 CBS domain 114 163 9.8E-7 T 13-10-2018 IPR000644 CBS domain Spica_1230 e1791aefa7a9173dcc676b2131cf738f 260 Pfam PF00571 CBS domain 44 102 3.5E-5 T 13-10-2018 IPR000644 CBS domain Spica_2091 08c4d3e2ae44ea8c8a2a51552e2143bf 259 Pfam PF01925 Sulfite exporter TauE/SafE 12 255 6.8E-18 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 Pfam PF00764 Arginosuccinate synthase 6 390 8.1E-156 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 SUPERFAMILY SSF69864 172 398 3.01E-89 T 13-10-2018 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 391 2.3E-148 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 Gene3D G3DSA:3.40.50.620 5 170 3.7E-156 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 Gene3D G3DSA:1.20.5.470 374 400 1.9E-7 T 13-10-2018 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 Gene3D G3DSA:3.90.1260.10 63 353 3.7E-156 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 SUPERFAMILY SSF52402 2 197 1.43E-46 T 13-10-2018 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0887 69ee57303e99c5dfc8b26d18010238d7 419 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 398 52.793 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0860 8a887b5b999352145ed5068f5bbd61e7 365 Pfam PF00882 Zinc dependent phospholipase C 26 153 3.2E-6 T 13-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 Spica_1922 985d9d0cc17bfa3f6c5d665a4d7c52e6 487 Pfam PF05598 Transposase domain (DUF772) 53 123 2.1E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_1922 985d9d0cc17bfa3f6c5d665a4d7c52e6 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_0804 985d9d0cc17bfa3f6c5d665a4d7c52e6 487 Pfam PF05598 Transposase domain (DUF772) 53 123 2.1E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_0804 985d9d0cc17bfa3f6c5d665a4d7c52e6 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_0503 ca133652b05c20a939856deeb6505ddd 433 Pfam PF13175 AAA ATPase domain 4 347 5.4E-30 T 13-10-2018 Spica_0503 ca133652b05c20a939856deeb6505ddd 433 SUPERFAMILY SSF52540 5 355 4.46E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0503 ca133652b05c20a939856deeb6505ddd 433 Gene3D G3DSA:3.40.50.300 1 372 3.1E-15 T 13-10-2018 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 348 359 - T 13-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 Pfam PF01268 Formate--tetrahydrofolate ligase 11 584 1.2E-255 T 13-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 9 584 43.906 T 13-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 Gene3D G3DSA:3.10.410.10 471 560 5.3E-38 T 13-10-2018 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 Gene3D G3DSA:3.30.1510.10 136 267 1.6E-191 T 13-10-2018 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 110 120 - T 13-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Spica_2498 f06403907ad04f7657d19219fd3f8838 584 SUPERFAMILY SSF52540 12 582 3.29E-229 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2498 f06403907ad04f7657d19219fd3f8838 584 Gene3D G3DSA:3.40.50.300 12 456 1.6E-191 T 13-10-2018 Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 202 32.919 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 PIRSF PIRSF000495 1 202 3.0E-69 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 SUPERFAMILY SSF52317 2 193 5.77E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 Gene3D G3DSA:3.40.50.880 1 202 1.4E-66 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 Pfam PF00117 Glutamine amidotransferase class-I 4 190 1.4E-19 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_0522 2abb8c9e29b0636337d17aa11a4ea1be 202 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 201 2.2E-67 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_1873 ceef954c704118a2af2a99d660d06055 420 Gene3D G3DSA:3.40.50.300 17 187 5.2E-31 T 13-10-2018 Spica_1873 ceef954c704118a2af2a99d660d06055 420 Gene3D G3DSA:3.40.50.11410 303 409 3.0E-30 T 13-10-2018 Spica_1873 ceef954c704118a2af2a99d660d06055 420 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 16 405 3.2E-132 T 13-10-2018 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF Spica_1873 ceef954c704118a2af2a99d660d06055 420 Gene3D G3DSA:3.40.50.11420 194 302 1.4E-38 T 13-10-2018 Spica_1873 ceef954c704118a2af2a99d660d06055 420 SUPERFAMILY SSF52540 14 181 5.74E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1873 ceef954c704118a2af2a99d660d06055 420 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 22 156 8.1E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_1873 ceef954c704118a2af2a99d660d06055 420 Pfam PF01926 50S ribosome-binding GTPase 24 136 1.5E-17 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0088 528c38001e336e306448de7742cb9ce1 304 Gene3D G3DSA:1.10.3720.10 18 291 5.1E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0088 528c38001e336e306448de7742cb9ce1 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 287 1.2E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0088 528c38001e336e306448de7742cb9ce1 304 SUPERFAMILY SSF161098 21 304 2.99E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0047 463b567dbfc2992dae0cf79317820a19 562 Pfam PF13487 HD domain 436 496 2.6E-17 T 13-10-2018 Spica_0047 463b567dbfc2992dae0cf79317820a19 562 Gene3D G3DSA:1.10.3210.10 360 558 6.5E-60 T 13-10-2018 Spica_0047 463b567dbfc2992dae0cf79317820a19 562 SUPERFAMILY SSF109604 370 550 2.07E-30 T 13-10-2018 Spica_0047 463b567dbfc2992dae0cf79317820a19 562 SMART SM00471 381 515 1.2E-6 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Gene3D G3DSA:2.60.40.10 752 867 5.2E-17 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Pfam PF02929 Beta galactosidase small chain 919 1207 1.3E-53 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 463 488 - T 13-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 523 537 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Pfam PF16353 Domain of unknown function(DUF4981) 762 862 2.3E-15 T 13-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SUPERFAMILY SSF49303 325 411 4.6E-13 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Gene3D G3DSA:2.70.98.10 926 1209 7.8E-63 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SUPERFAMILY SSF49303 759 864 2.88E-14 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SMART SM01038 916 1208 2.1E-58 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SUPERFAMILY SSF74650 928 1208 1.4E-56 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Gene3D G3DSA:3.20.20.80 412 725 6.1E-104 T 13-10-2018 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Gene3D G3DSA:2.60.40.10 294 411 6.6E-15 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SUPERFAMILY SSF51445 413 726 2.02E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Gene3D G3DSA:2.60.120.260 1 242 4.6E-70 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 PRINTS PR00132 Glycosyl hydrolase family 2 signature 171 186 9.0E-13 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 PRINTS PR00132 Glycosyl hydrolase family 2 signature 523 538 9.0E-13 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 PRINTS PR00132 Glycosyl hydrolase family 2 signature 611 626 9.0E-13 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Pfam PF00703 Glycosyl hydrolases family 2 363 411 3.5E-7 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 413 730 5.3E-94 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 SUPERFAMILY SSF49785 3 242 8.93E-55 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_1913 521e5cb677dba427f10f711deca65e5f 1210 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 58 242 1.4E-36 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_2598 3b1d0e475c96765c8859265a50e1bfed 649 Gene3D G3DSA:2.40.170.20 166 649 1.6E-62 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Spica_2598 3b1d0e475c96765c8859265a50e1bfed 649 Pfam PF00593 TonB dependent receptor 192 648 4.3E-36 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Spica_2598 3b1d0e475c96765c8859265a50e1bfed 649 SUPERFAMILY SSF56935 26 649 9.89E-99 T 13-10-2018 Spica_2598 3b1d0e475c96765c8859265a50e1bfed 649 Pfam PF07715 TonB-dependent Receptor Plug Domain 36 145 5.2E-27 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Spica_2598 3b1d0e475c96765c8859265a50e1bfed 649 Gene3D G3DSA:2.170.130.10 20 150 1.6E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Spica_0535 8962cfa7b81ec86ca06e7ee3997cd162 372 SUPERFAMILY SSF51735 5 366 6.03E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0535 8962cfa7b81ec86ca06e7ee3997cd162 372 Gene3D G3DSA:3.40.50.720 7 341 6.2E-127 T 13-10-2018 Spica_0535 8962cfa7b81ec86ca06e7ee3997cd162 372 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 7 354 3.0E-143 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Spica_0535 8962cfa7b81ec86ca06e7ee3997cd162 372 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 342 1.5E-100 T 13-10-2018 IPR016040 NAD(P)-binding domain Spica_0535 8962cfa7b81ec86ca06e7ee3997cd162 372 Gene3D G3DSA:3.90.25.10 220 349 6.2E-127 T 13-10-2018 Spica_2764 956867f690dc530b05cae480ad915752 162 Pfam PF02577 Bifunctional nuclease 10 134 7.4E-20 T 13-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 Spica_2764 956867f690dc530b05cae480ad915752 162 Gene3D G3DSA:3.10.690.10 1 143 1.1E-15 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Spica_2764 956867f690dc530b05cae480ad915752 162 SUPERFAMILY SSF103256 7 135 5.89E-13 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 SUPERFAMILY SSF52540 31 543 6.49E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0017 4d51935f440d56e2c3297f1caa663932 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 570 586 9.1E-13 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 651 670 9.1E-13 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 59 78 9.1E-13 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 681 700 9.1E-13 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 711 729 9.1E-13 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Gene3D G3DSA:3.30.230.10 545 775 5.2E-86 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Pfam PF13654 AAA domain 24 542 1.5E-150 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 SUPERFAMILY SSF54211 569 761 3.79E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 760 2.7E-12 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Gene3D G3DSA:3.40.50.300 7 172 1.6E-21 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Gene3D G3DSA:3.40.50.300 226 454 1.8E-49 T 13-10-2018 Spica_0017 4d51935f440d56e2c3297f1caa663932 798 Gene3D G3DSA:1.10.8.60 455 541 1.8E-6 T 13-10-2018 Spica_0635 253f50c386f08c93a588d93a0d3a228f 310 SUPERFAMILY SSF161098 66 295 1.44E-44 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0635 253f50c386f08c93a588d93a0d3a228f 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 304 1.3E-9 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0635 253f50c386f08c93a588d93a0d3a228f 310 Gene3D G3DSA:1.10.3720.10 62 310 2.5E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1448 8d26c7f2b9a5e4f28c9e2df72262d0d5 428 Gene3D G3DSA:3.90.1150.10 301 425 8.0E-34 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1448 8d26c7f2b9a5e4f28c9e2df72262d0d5 428 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 419 1.4E-107 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_1448 8d26c7f2b9a5e4f28c9e2df72262d0d5 428 PIRSF PIRSF000390 3 425 4.5E-94 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_1448 8d26c7f2b9a5e4f28c9e2df72262d0d5 428 Gene3D G3DSA:3.40.640.10 1 298 2.6E-86 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1448 8d26c7f2b9a5e4f28c9e2df72262d0d5 428 SUPERFAMILY SSF53383 7 422 3.8E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2389 724e9f21b0450a2be721af7e9119e5e3 181 Pfam PF01966 HD domain 23 89 1.1E-4 T 13-10-2018 IPR006674 HD domain Spica_2389 724e9f21b0450a2be721af7e9119e5e3 181 TIGRFAM TIGR00277 HDIG: HDIG domain 19 88 4.4E-8 T 13-10-2018 IPR006675 HDIG domain Spica_2389 724e9f21b0450a2be721af7e9119e5e3 181 SUPERFAMILY SSF109604 12 113 2.61E-14 T 13-10-2018 Spica_2389 724e9f21b0450a2be721af7e9119e5e3 181 Gene3D G3DSA:1.10.3210.10 4 151 2.7E-9 T 13-10-2018 Spica_2012 fb0e4b546830e1d06497a10953465c67 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 381 487 9.8E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2012 fb0e4b546830e1d06497a10953465c67 490 SMART SM00304 200 253 3.2E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2012 fb0e4b546830e1d06497a10953465c67 490 SUPERFAMILY SSF55874 337 485 8.51E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2012 fb0e4b546830e1d06497a10953465c67 490 Pfam PF06580 Histidine kinase 282 360 2.3E-21 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_2012 fb0e4b546830e1d06497a10953465c67 490 Pfam PF00672 HAMP domain 202 249 2.8E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2012 fb0e4b546830e1d06497a10953465c67 490 SUPERFAMILY SSF158472 202 251 2.09E-9 T 13-10-2018 Spica_2012 fb0e4b546830e1d06497a10953465c67 490 SMART SM00387 376 488 1.3E-6 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2012 fb0e4b546830e1d06497a10953465c67 490 Gene3D G3DSA:3.30.565.10 351 489 5.6E-20 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2012 fb0e4b546830e1d06497a10953465c67 490 Gene3D G3DSA:1.20.1480.50 165 259 8.6E-14 T 13-10-2018 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 431 440 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Gene3D G3DSA:3.40.50.300 77 438 7.2E-153 T 13-10-2018 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 88 209 1.1E-33 T 13-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 3 577 43.842 T 13-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 SUPERFAMILY SSF52540 173 444 1.05E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 220 440 1.6E-76 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Gene3D G3DSA:2.40.30.20 4 75 2.5E-11 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Gene3D G3DSA:2.40.50.100 119 191 7.2E-153 T 13-10-2018 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 72 4.2E-9 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1503 5de3852ce116e421c3fa8f89910b3499 586 Gene3D G3DSA:1.10.1140.10 439 575 1.3E-11 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 SUPERFAMILY SSF52540 1 406 3.19E-137 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 Gene3D G3DSA:3.40.440.10 4 232 7.8E-75 T 13-10-2018 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 Gene3D G3DSA:1.10.300.10 100 176 7.8E-75 T 13-10-2018 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 Pfam PF00709 Adenylosuccinate synthetase 3 400 4.2E-149 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 SMART SM00788 2 401 5.5E-201 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 9 16 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 408 153.875 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 4 401 3.1E-137 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Spica_1848 74efae7ef5fdd1f8637395af5900e100 408 Gene3D G3DSA:3.90.170.10 240 408 5.7E-64 T 13-10-2018 Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 Pfam PF13581 Histidine kinase-like ATPase domain 163 297 5.2E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 SUPERFAMILY SSF55874 174 299 7.15E-9 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 SMART SM00100 296 416 2.9E-8 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 Pfam PF00027 Cyclic nucleotide-binding domain 318 401 3.4E-16 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 Gene3D G3DSA:2.60.120.10 309 428 5.0E-24 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 Gene3D G3DSA:3.30.565.10 150 308 8.8E-9 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2841 1d691719cdaa9af68e5d726cebdfdeaa 462 SUPERFAMILY SSF51206 311 416 7.07E-24 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0600 f60b7f337bf71ee18ee695831680dcdd 541 Pfam PF13416 Bacterial extracellular solute-binding protein 76 317 1.3E-10 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0600 f60b7f337bf71ee18ee695831680dcdd 541 SUPERFAMILY SSF53850 43 536 1.15E-48 T 13-10-2018 Spica_0600 f60b7f337bf71ee18ee695831680dcdd 541 Gene3D G3DSA:3.40.190.10 173 426 3.1E-26 T 13-10-2018 Spica_0600 f60b7f337bf71ee18ee695831680dcdd 541 Gene3D G3DSA:3.40.190.10 49 160 7.2E-13 T 13-10-2018 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 76 5.1E-31 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 Pfam PF01016 Ribosomal L27 protein 2 79 8.1E-34 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.1E-33 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.1E-33 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.1E-33 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 25.697 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 Gene3D G3DSA:2.40.50.100 21 86 5.3E-26 T 13-10-2018 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 SUPERFAMILY SSF110324 2 76 4.53E-29 T 13-10-2018 Spica_0784 87f12805e73f069f42e7b0f3abc2a102 87 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 5.0E-14 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 3.3E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 2 12 3.3E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 SUPERFAMILY SSF47413 1 50 2.72E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 Gene3D G3DSA:1.10.260.40 1 55 3.7E-15 T 13-10-2018 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 SMART SM00354 1 69 1.2E-13 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 46 2.3E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 Gene3D G3DSA:3.40.50.2300 159 327 5.9E-51 T 13-10-2018 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 SUPERFAMILY SSF53822 59 331 7.28E-47 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 Pfam PF13377 Periplasmic binding protein-like domain 168 330 1.6E-26 T 13-10-2018 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 Gene3D G3DSA:3.40.50.2300 60 322 5.9E-51 T 13-10-2018 Spica_2224 b4b48dfa612a709137e6c7b10c122ed1 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 13-10-2018 Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 SUPERFAMILY SSF55021 142 201 4.58E-7 T 13-10-2018 Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 SMART SM00116 10 58 6.4E-14 T 13-10-2018 IPR000644 CBS domain Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 SMART SM00116 85 132 1.7E-10 T 13-10-2018 IPR000644 CBS domain Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 Gene3D G3DSA:3.30.70.260 143 214 1.1E-6 T 13-10-2018 Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 Gene3D G3DSA:3.10.580.10 1 142 1.3E-44 T 13-10-2018 Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 Pfam PF00571 CBS domain 3 56 6.7E-15 T 13-10-2018 IPR000644 CBS domain Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 Pfam PF00571 CBS domain 78 130 1.4E-15 T 13-10-2018 IPR000644 CBS domain Spica_0418 7ad82a77d75c105fda35a15863f8f79b 214 SUPERFAMILY SSF54631 1 133 3.41E-37 T 13-10-2018 Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.5E-43 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.1E-13 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.1E-13 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.1E-13 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 2.7E-55 T 13-10-2018 Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 8 256 9.1E-118 T 13-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 SUPERFAMILY SSF51735 12 253 5.75E-73 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_0628 208ab9c9e0d9fb0d5cd7dfc2b2b8332b 256 Gene3D G3DSA:3.40.50.720 4 255 8.6E-76 T 13-10-2018 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PRINTS PR00143 Citrate synthase signature 168 181 8.3E-32 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PRINTS PR00143 Citrate synthase signature 377 393 8.3E-32 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PRINTS PR00143 Citrate synthase signature 224 239 8.3E-32 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PRINTS PR00143 Citrate synthase signature 247 275 8.3E-32 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PRINTS PR00143 Citrate synthase signature 397 411 8.3E-32 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 Pfam PF00285 Citrate synthase, C-terminal domain 37 428 2.9E-116 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 SUPERFAMILY SSF48256 5 435 5.5E-94 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 Gene3D G3DSA:1.10.580.10 62 416 1.8E-109 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 PIRSF PIRSF001369 57 445 2.2E-84 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type Spica_1627 8c79315451108d8fb4fe4ec869ef10ca 445 Gene3D G3DSA:1.10.230.10 273 391 1.8E-109 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 ProSitePatterns PS00517 Ribonuclease III family signature. 61 69 - T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 Gene3D G3DSA:3.30.160.20 178 244 1.2E-22 T 13-10-2018 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 SMART SM00535 39 172 4.2E-46 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 Gene3D G3DSA:1.10.1520.10 23 170 1.9E-38 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 Pfam PF14622 Ribonuclease-III-like 39 162 1.6E-28 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 SUPERFAMILY SSF54768 133 245 2.04E-27 T 13-10-2018 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 27 244 1.8E-73 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 Pfam PF00035 Double-stranded RNA binding motif 179 243 1.9E-16 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 SUPERFAMILY SSF69065 20 180 5.06E-41 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 SMART SM00358 179 246 6.8E-23 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain Spica_1404 b5afc21a04344a1f6067509edbd6ca20 249 Hamap MF_00104 Ribonuclease 3 [rnc]. 27 242 28.726 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Spica_1470 c86b8427bca411710262435dd471048d 480 Pfam PF02397 Bacterial sugar transferase 283 474 1.0E-68 T 13-10-2018 IPR003362 Bacterial sugar transferase Spica_1470 c86b8427bca411710262435dd471048d 480 SUPERFAMILY SSF51735 152 234 1.02E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1470 c86b8427bca411710262435dd471048d 480 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 27 480 3.0E-145 T 13-10-2018 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 Spica_1470 c86b8427bca411710262435dd471048d 480 Pfam PF13727 CoA-binding domain 86 235 6.0E-10 T 13-10-2018 Spica_1470 c86b8427bca411710262435dd471048d 480 Gene3D G3DSA:3.40.50.720 151 266 5.7E-15 T 13-10-2018 Spica_1470 c86b8427bca411710262435dd471048d 480 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 29 480 9.7E-120 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Spica_0919 db62abf5c8ac559c5bd6654898735923 506 Pfam PF00005 ABC transporter 274 430 1.9E-14 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0919 db62abf5c8ac559c5bd6654898735923 506 Pfam PF00005 ABC transporter 21 169 1.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0919 db62abf5c8ac559c5bd6654898735923 506 SUPERFAMILY SSF52540 241 492 4.91E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0919 db62abf5c8ac559c5bd6654898735923 506 SMART SM00382 282 479 10.0 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0919 db62abf5c8ac559c5bd6654898735923 506 SMART SM00382 29 217 4.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0919 db62abf5c8ac559c5bd6654898735923 506 Gene3D G3DSA:3.40.50.300 256 498 7.7E-39 T 13-10-2018 Spica_0919 db62abf5c8ac559c5bd6654898735923 506 SUPERFAMILY SSF52540 3 227 7.5E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0919 db62abf5c8ac559c5bd6654898735923 506 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0919 db62abf5c8ac559c5bd6654898735923 506 Gene3D G3DSA:3.40.50.300 2 239 8.9E-57 T 13-10-2018 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 367 390 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 1 614 40.444 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Pfam PF13932 GidA associated domain 400 605 8.9E-70 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 3 610 8.9E-253 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Pfam PF01134 Glucose inhibited division protein A 4 398 3.1E-149 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 SUPERFAMILY SSF51905 1 260 8.16E-42 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.8E-6 T 13-10-2018 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 3.8E-6 T 13-10-2018 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Gene3D G3DSA:1.10.150.570 559 611 6.1E-19 T 13-10-2018 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Gene3D G3DSA:3.50.50.60 295 457 7.0E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 Gene3D G3DSA:3.50.50.60 1 223 2.5E-81 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 272 286 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Spica_2099 55e54d0e25b3f64ef8df396bd21b5190 616 SMART SM01228 536 607 1.5E-32 T 13-10-2018 Spica_1577 70d989da338d13742880730477fc3a70 177 SUPERFAMILY SSF52540 7 170 2.34E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1577 70d989da338d13742880730477fc3a70 177 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 8 173 1.9E-41 T 13-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Spica_1577 70d989da338d13742880730477fc3a70 177 Pfam PF13189 Cytidylate kinase-like family 8 159 1.9E-14 T 13-10-2018 Spica_1577 70d989da338d13742880730477fc3a70 177 Hamap MF_00239 Cytidylate kinase [cmk]. 6 177 39.814 T 13-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Spica_1577 70d989da338d13742880730477fc3a70 177 Gene3D G3DSA:3.40.50.300 1 177 4.7E-38 T 13-10-2018 Spica_1589 bff4e6580ceb83dfbcd15eb9b0f61790 360 Pfam PF07238 PilZ domain 216 326 2.1E-9 T 13-10-2018 IPR009875 PilZ domain GO:0035438 Spica_1999 6ea63e532c0e964129bea216c62e45a1 447 Gene3D G3DSA:1.20.1600.10 236 430 1.4E-5 T 13-10-2018 Spica_1999 6ea63e532c0e964129bea216c62e45a1 447 Gene3D G3DSA:1.20.1600.10 3 235 5.8E-22 T 13-10-2018 Spica_1999 6ea63e532c0e964129bea216c62e45a1 447 SUPERFAMILY SSF56954 7 425 2.49E-23 T 13-10-2018 Spica_1999 6ea63e532c0e964129bea216c62e45a1 447 Pfam PF02321 Outer membrane efflux protein 29 236 4.8E-11 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 SMART SM00382 302 504 8.4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 SMART SM00382 32 237 7.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 Pfam PF00005 ABC transporter 23 189 4.3E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 Gene3D G3DSA:3.40.50.300 276 530 2.6E-38 T 13-10-2018 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 SUPERFAMILY SSF52540 273 519 8.76E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 Gene3D G3DSA:3.40.50.300 3 253 1.7E-52 T 13-10-2018 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 Pfam PF00005 ABC transporter 294 455 3.7E-13 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0540 c6dedbba632a1d6bc63492c9aa9132cb 537 SUPERFAMILY SSF52540 6 245 7.22E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0300 4b1c880443d861009683c4c652593055 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 7.0E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_0300 4b1c880443d861009683c4c652593055 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 7.0E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_0300 4b1c880443d861009683c4c652593055 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 7.0E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_0300 4b1c880443d861009683c4c652593055 161 Gene3D G3DSA:1.10.10.10 32 160 1.2E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0300 4b1c880443d861009683c4c652593055 161 SMART SM00347 43 145 6.4E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_0300 4b1c880443d861009683c4c652593055 161 SUPERFAMILY SSF46785 35 157 1.39E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0300 4b1c880443d861009683c4c652593055 161 Pfam PF01047 MarR family 51 106 8.6E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_2469 bcbb33bbf919adc462b5aa607a4b6bac 405 SUPERFAMILY SSF53474 164 400 2.15E-30 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2469 bcbb33bbf919adc462b5aa607a4b6bac 405 Pfam PF12146 Serine aminopeptidase, S33 175 384 4.7E-23 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Spica_2469 bcbb33bbf919adc462b5aa607a4b6bac 405 Gene3D G3DSA:3.40.50.1820 156 405 1.1E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2109 cd8eefa498540378c60200a0502c83a3 229 SMART SM00478 55 202 5.9E-51 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 SUPERFAMILY SSF48150 41 221 6.6E-63 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 204 220 - T 13-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 Gene3D G3DSA:1.10.340.30 40 149 2.5E-62 T 13-10-2018 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 ProSitePatterns PS01155 Endonuclease III family signature. 119 148 - T 13-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 Gene3D G3DSA:1.10.1670.10 150 220 2.5E-62 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 SMART SM00525 203 223 0.0051 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 Pfam PF00633 Helix-hairpin-helix motif 117 144 2.9E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 Hamap MF_00942 Endonuclease III [nth]. 1 226 30.038 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 PIRSF PIRSF001435 29 228 4.8E-43 T 13-10-2018 Spica_2109 cd8eefa498540378c60200a0502c83a3 229 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 51 185 1.6E-19 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_2661 bd31fb7714313c9d26cefcb6387fdb6d 131 SUPERFAMILY SSF88723 1 122 7.01E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2661 bd31fb7714313c9d26cefcb6387fdb6d 131 Pfam PF01850 PIN domain 3 124 3.7E-8 T 13-10-2018 IPR002716 PIN domain Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SMART SM00448 666 779 1.1E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SUPERFAMILY SSF49785 17 172 4.93E-8 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 866 6.1E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 824 838 6.1E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 838 854 6.1E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SUPERFAMILY SSF55874 468 641 2.23E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SMART SM00387 527 640 5.4E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SMART SM00421 821 878 3.0E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SUPERFAMILY SSF52172 667 792 4.41E-30 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SMART SM00388 410 478 4.1E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 579 1.7E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 637 1.7E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 618 1.7E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Pfam PF00196 Bacterial regulatory proteins, luxR family 823 877 1.6E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 637 4.9E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Pfam PF07695 7TM diverse intracellular signalling 191 385 7.6E-19 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Pfam PF00072 Response regulator receiver domain 668 779 3.7E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Gene3D G3DSA:2.60.120.260 16 173 1.1E-7 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Gene3D G3DSA:1.10.287.130 402 479 2.7E-15 T 13-10-2018 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Gene3D G3DSA:3.40.50.2300 665 804 2.5E-29 T 13-10-2018 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SUPERFAMILY SSF47384 397 478 1.96E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Gene3D G3DSA:1.10.10.10 805 879 5.2E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Pfam PF00512 His Kinase A (phospho-acceptor) domain 411 478 1.3E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 Gene3D G3DSA:3.30.565.10 480 643 1.1E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0743 1e5f03237d0b332c2502b7e137acf82c 883 SUPERFAMILY SSF46894 815 878 1.8E-14 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 214 402 9.4E-83 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 204 1.0E-65 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 203 8.9E-79 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 Pfam PF00925 GTP cyclohydrolase II 214 378 2.9E-72 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 PIRSF PIRSF001259 1 406 2.8E-161 T 13-10-2018 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 209 404 41.818 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 SUPERFAMILY SSF142695 211 380 1.31E-66 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 Gene3D G3DSA:3.40.50.10990 211 382 1.4E-77 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 SUPERFAMILY SSF55821 2 207 5.26E-70 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_0168 479343ae43ad3451e1ebe32573c6fed5 407 Gene3D G3DSA:3.90.870.10 1 210 2.0E-80 T 13-10-2018 Spica_0431 21a66c9e39f1a09f569bf3c131cb3360 351 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 342 2.5E-141 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Spica_0431 21a66c9e39f1a09f569bf3c131cb3360 351 SUPERFAMILY SSF51569 6 345 6.07E-127 T 13-10-2018 Spica_0431 21a66c9e39f1a09f569bf3c131cb3360 351 Pfam PF00793 DAHP synthetase I family 40 338 2.9E-88 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Spica_0431 21a66c9e39f1a09f569bf3c131cb3360 351 PIRSF PIRSF001361 1 351 2.1E-153 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Spica_0431 21a66c9e39f1a09f569bf3c131cb3360 351 Gene3D G3DSA:3.20.20.70 1 348 2.6E-149 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 Gene3D G3DSA:3.20.20.80 184 587 3.2E-108 T 13-10-2018 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 187 566 7.7E-92 T 13-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 SUPERFAMILY SSF51445 187 579 7.07E-100 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 530 546 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 180 197 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 548 565 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 209 230 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 269 286 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1933 01eb1cab9d985b79f1f960f1ee595cbf 604 PRINTS PR00738 Glycosyl hydrolase family 20 signature 339 352 3.5E-33 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SUPERFAMILY SSF55874 239 391 1.03E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 149 6.3E-9 T 13-10-2018 IPR000014 PAS domain Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Gene3D G3DSA:3.30.450.20 25 140 3.2E-14 T 13-10-2018 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 237 4.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 390 4.6E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 6.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 6.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 323 337 6.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 351 6.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SMART SM00387 286 392 3.3E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Pfam PF08448 PAS fold 38 143 1.9E-7 T 13-10-2018 IPR013656 PAS fold-4 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Gene3D G3DSA:3.30.565.10 244 399 4.4E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SUPERFAMILY SSF47384 146 240 1.37E-8 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SMART SM00091 32 99 6.1E-5 T 13-10-2018 IPR000014 PAS domain Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 Gene3D G3DSA:1.10.287.130 143 242 9.3E-18 T 13-10-2018 Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SUPERFAMILY SSF55785 28 140 3.32E-9 T 13-10-2018 IPR035965 PAS domain superfamily Spica_1510 ba803131094ed2f5d36ae83a84366c2c 405 SMART SM00388 157 244 9.8E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_1378 dbba00bcb0750b7206876627ae951511 210 SUPERFAMILY SSF52540 1 209 2.67E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1378 dbba00bcb0750b7206876627ae951511 210 Pfam PF02224 Cytidylate kinase 3 209 5.8E-70 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Spica_1378 dbba00bcb0750b7206876627ae951511 210 Hamap MF_00238 Cytidylate kinase [cmk]. 1 210 27.201 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Spica_1378 dbba00bcb0750b7206876627ae951511 210 Gene3D G3DSA:3.40.50.300 1 210 3.0E-73 T 13-10-2018 Spica_1378 dbba00bcb0750b7206876627ae951511 210 TIGRFAM TIGR00017 cmk: cytidylate kinase 1 207 2.0E-61 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Gene3D G3DSA:3.30.930.10 123 615 3.5E-182 T 13-10-2018 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Pfam PF02938 GAD domain 338 438 8.0E-16 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 5 618 32.684 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Gene3D G3DSA:2.40.50.140 1 112 3.8E-36 T 13-10-2018 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Gene3D G3DSA:3.30.1360.30 279 453 3.5E-182 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 SUPERFAMILY SSF55681 119 615 4.02E-104 T 13-10-2018 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 4 615 2.1E-215 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Pfam PF01336 OB-fold nucleic acid binding domain 22 106 1.6E-14 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 SUPERFAMILY SSF55261 296 452 2.83E-24 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 Pfam PF00152 tRNA synthetases class II (D, K and N) 125 591 2.0E-104 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 PRINTS PR01042 Aspartyl-tRNA synthetase signature 552 566 7.7E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 209 7.7E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 PRINTS PR01042 Aspartyl-tRNA synthetase signature 214 227 7.7E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 PRINTS PR01042 Aspartyl-tRNA synthetase signature 508 524 7.7E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0269 ece437551c42bdc644f8f7baaf580c5e 624 SUPERFAMILY SSF50249 6 110 1.22E-31 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Gene3D G3DSA:3.40.50.970 2 187 1.3E-69 T 13-10-2018 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 540 1.0E-49 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Gene3D G3DSA:3.40.50.970 364 572 8.7E-66 T 13-10-2018 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 339 5.6E-45 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 SUPERFAMILY SSF52467 166 368 5.97E-56 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Gene3D G3DSA:3.40.50.1220 197 362 4.3E-59 T 13-10-2018 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 SUPERFAMILY SSF52518 12 190 3.81E-60 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 178 4.7E-59 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 15 564 2.2E-226 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2690 2d8d4a564fa1ec81b73a450bdcb4c948 578 SUPERFAMILY SSF52518 370 566 1.97E-66 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 8.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 8.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 8.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 SUPERFAMILY SSF56784 1 222 1.25E-49 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 193 9.2E-27 T 13-10-2018 Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 Gene3D G3DSA:3.40.50.1000 6 214 7.1E-50 T 13-10-2018 IPR023214 HAD superfamily Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 187 3.5E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0701 9cf41e488a3618280aef74a7c042d32a 223 Gene3D G3DSA:1.10.150.240 18 92 7.1E-50 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_2313 29b8de2b24fdcd4a3ca3f8df5cb22c69 667 Pfam PF01841 Transglutaminase-like superfamily 428 529 1.3E-22 T 13-10-2018 IPR002931 Transglutaminase-like Spica_2313 29b8de2b24fdcd4a3ca3f8df5cb22c69 667 Gene3D G3DSA:3.10.620.30 403 542 1.6E-20 T 13-10-2018 Spica_2313 29b8de2b24fdcd4a3ca3f8df5cb22c69 667 SMART SM00460 463 531 2.2E-23 T 13-10-2018 IPR002931 Transglutaminase-like Spica_2313 29b8de2b24fdcd4a3ca3f8df5cb22c69 667 SUPERFAMILY SSF54001 399 620 3.63E-29 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 Gene3D G3DSA:3.30.110.10 80 172 6.4E-37 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 8 75 1.6E-32 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 SUPERFAMILY SSF55200 84 172 5.23E-32 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 2 171 30.747 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 Gene3D G3DSA:3.10.20.80 2 79 8.4E-34 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 8 171 4.3E-69 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 1.9E-36 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 ProSitePatterns PS00938 Initiation factor 3 signature. 59 72 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 Spica_1697 aaaa08c59a5a13cce37a0a281f092380 172 SUPERFAMILY SSF54364 6 79 6.93E-30 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 915 1590 1.0E-170 T 13-10-2018 IPR011840 Pullulanase, type I Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 Pfam PF00128 Alpha amylase, catalytic domain 1106 1210 4.4E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 SMART SM00642 1093 1464 4.3E-5 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 Pfam PF06202 Amylo-alpha-1,6-glucosidase 335 707 3.0E-80 T 13-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 Gene3D G3DSA:2.60.40.10 912 1049 1.7E-24 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 SUPERFAMILY SSF81296 922 1070 1.94E-18 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 SUPERFAMILY SSF48208 300 733 2.76E-60 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 Gene3D G3DSA:3.20.20.80 1050 1530 2.5E-135 T 13-10-2018 Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 SUPERFAMILY SSF51445 1050 1519 9.22E-94 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0085 0980a56a9628b6b53bf347eaf53b3946 1620 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 988 1032 8.6E-6 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 Spica_2046 de793ea393b218457fde889daad1666b 308 Gene3D G3DSA:3.30.70.1350 209 292 5.3E-25 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Spica_2046 de793ea393b218457fde889daad1666b 308 SUPERFAMILY SSF160240 213 291 3.66E-17 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Spica_2046 de793ea393b218457fde889daad1666b 308 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 291 1.7E-60 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spica_2046 de793ea393b218457fde889daad1666b 308 Pfam PF01545 Cation efflux family 14 208 5.7E-37 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Spica_2046 de793ea393b218457fde889daad1666b 308 Pfam PF16916 Dimerisation domain of Zinc Transporter 216 290 1.4E-19 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Spica_2046 de793ea393b218457fde889daad1666b 308 SUPERFAMILY SSF161111 7 209 8.24E-46 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Spica_2046 de793ea393b218457fde889daad1666b 308 Gene3D G3DSA:1.20.1510.10 8 208 3.0E-45 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07495 Y_Y_Y domain 720 780 2.2E-16 T 13-10-2018 IPR011123 Two component regulator three Y Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Gene3D G3DSA:2.60.40.10 667 792 1.6E-28 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Gene3D G3DSA:2.130.10.10 22 271 2.9E-66 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 SUPERFAMILY SSF63829 16 195 1.31E-11 T 13-10-2018 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 SUPERFAMILY SSF55073 830 990 1.65E-47 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 587 608 1.2E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 403 425 5.3E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 356 376 0.0082 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 543 565 0.0027 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 34 56 4.2E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF07494 Two component regulator propeller 220 241 8.8E-4 T 13-10-2018 IPR011110 Two component regulator propeller Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Gene3D G3DSA:2.130.10.10 348 663 1.1E-69 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 SMART SM00267 814 990 2.0E-65 T 13-10-2018 IPR000160 GGDEF domain Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Gene3D G3DSA:3.30.70.270 810 990 4.2E-57 T 13-10-2018 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 SUPERFAMILY SSF63829 464 663 8.5E-13 T 13-10-2018 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 SUPERFAMILY SSF63829 177 399 1.37E-15 T 13-10-2018 Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 821 988 3.4E-48 T 13-10-2018 IPR000160 GGDEF domain Spica_2337 8d64f91d2e94dd29d8fe7839932c90e3 991 Pfam PF00990 Diguanylate cyclase, GGDEF domain 827 985 1.2E-47 T 13-10-2018 IPR000160 GGDEF domain Spica_0909 ba8ed756315e4c2de6a3e4072f8f7950 201 Pfam PF01381 Helix-turn-helix 7 61 3.0E-20 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0909 ba8ed756315e4c2de6a3e4072f8f7950 201 SMART SM00530 6 61 4.3E-21 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0909 ba8ed756315e4c2de6a3e4072f8f7950 201 SUPERFAMILY SSF47413 1 66 3.49E-20 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0909 ba8ed756315e4c2de6a3e4072f8f7950 201 Gene3D G3DSA:1.10.260.40 1 64 1.4E-24 T 13-10-2018 Spica_2643 08752ce870459f176ae46239af0d2a39 422 Gene3D G3DSA:3.30.70.360 222 332 8.2E-153 T 13-10-2018 Spica_2643 08752ce870459f176ae46239af0d2a39 422 SUPERFAMILY SSF55031 222 332 2.82E-20 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Spica_2643 08752ce870459f176ae46239af0d2a39 422 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 151 190 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spica_2643 08752ce870459f176ae46239af0d2a39 422 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 87 96 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Spica_2643 08752ce870459f176ae46239af0d2a39 422 PIRSF PIRSF037215 12 421 9.1E-143 T 13-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 Spica_2643 08752ce870459f176ae46239af0d2a39 422 Gene3D G3DSA:3.40.630.10 17 413 8.2E-153 T 13-10-2018 Spica_2643 08752ce870459f176ae46239af0d2a39 422 TIGRFAM TIGR01882 peptidase-T: peptidase T 15 418 1.0E-115 T 13-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 Spica_2643 08752ce870459f176ae46239af0d2a39 422 Pfam PF01546 Peptidase family M20/M25/M40 152 415 5.6E-13 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 Spica_2643 08752ce870459f176ae46239af0d2a39 422 SUPERFAMILY SSF53187 15 418 9.02E-70 T 13-10-2018 Spica_2163 12b456a09280743601fe44c8a064e19f 287 SUPERFAMILY SSF53850 90 279 2.64E-32 T 13-10-2018 Spica_2163 12b456a09280743601fe44c8a064e19f 287 SUPERFAMILY SSF46785 5 108 1.9E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2163 12b456a09280743601fe44c8a064e19f 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spica_2163 12b456a09280743601fe44c8a064e19f 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spica_2163 12b456a09280743601fe44c8a064e19f 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spica_2163 12b456a09280743601fe44c8a064e19f 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Spica_2163 12b456a09280743601fe44c8a064e19f 287 Gene3D G3DSA:3.40.190.10 91 276 2.5E-33 T 13-10-2018 Spica_2163 12b456a09280743601fe44c8a064e19f 287 Gene3D G3DSA:3.40.190.10 162 267 2.5E-33 T 13-10-2018 Spica_2163 12b456a09280743601fe44c8a064e19f 287 Pfam PF03466 LysR substrate binding domain 90 277 2.4E-34 T 13-10-2018 IPR005119 LysR, substrate-binding Spica_2163 12b456a09280743601fe44c8a064e19f 287 Gene3D G3DSA:1.10.10.10 1 69 2.1E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0344 7880ad840203bea9d303fd5341d7b130 697 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 33 115 2.3E-13 T 13-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 Spica_0344 7880ad840203bea9d303fd5341d7b130 697 SUPERFAMILY SSF81296 30 113 7.0E-16 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0344 7880ad840203bea9d303fd5341d7b130 697 Gene3D G3DSA:2.60.40.10 25 117 2.6E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF12838 4Fe-4S dicluster domain 696 765 1.5E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2484 658fb0816215ab590b91360b4316a914 1185 PIRSF PIRSF000159 1 1185 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 SUPERFAMILY SSF52922 261 422 2.09E-48 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2484 658fb0816215ab590b91360b4316a914 1185 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 7 1182 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF10371 Domain of unknown function 637 686 2.7E-21 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 SUPERFAMILY SSF52518 803 1184 5.09E-129 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2484 658fb0816215ab590b91360b4316a914 1185 Gene3D G3DSA:3.40.920.10 424 632 2.0E-86 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 970 1082 4.5E-12 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Gene3D G3DSA:3.40.50.970 3 259 3.5E-110 T 13-10-2018 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 270 352 3.0E-14 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Spica_2484 658fb0816215ab590b91360b4316a914 1185 SUPERFAMILY SSF54862 673 845 9.63E-24 T 13-10-2018 Spica_2484 658fb0816215ab590b91360b4316a914 1185 SUPERFAMILY SSF52518 4 259 2.35E-79 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2484 658fb0816215ab590b91360b4316a914 1185 SMART SM00890 632 687 6.8E-21 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Gene3D G3DSA:3.40.50.970 802 1184 1.2E-162 T 13-10-2018 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Gene3D G3DSA:3.30.70.20 677 799 1.1E-42 T 13-10-2018 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Gene3D G3DSA:3.40.50.920 260 422 3.0E-63 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 434 616 1.5E-27 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 248 8.5E-85 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Spica_2484 658fb0816215ab590b91360b4316a914 1185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 697 708 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2484 658fb0816215ab590b91360b4316a914 1185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 753 764 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2484 658fb0816215ab590b91360b4316a914 1185 SUPERFAMILY SSF53323 425 676 1.05E-78 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_0782 565b02bdf6aa92c746709926d337d6c8 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.3E-36 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0782 565b02bdf6aa92c746709926d337d6c8 103 SUPERFAMILY SSF141091 1 100 2.35E-35 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0782 565b02bdf6aa92c746709926d337d6c8 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.1E-37 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0782 565b02bdf6aa92c746709926d337d6c8 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 13-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0782 565b02bdf6aa92c746709926d337d6c8 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.891 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0955 87b1af23ef6668d646f8444296db6639 100 SUPERFAMILY SSF46689 1 91 5.73E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0955 87b1af23ef6668d646f8444296db6639 100 Pfam PF01527 Transposase 2 64 6.8E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Spica_2182 87b1af23ef6668d646f8444296db6639 100 SUPERFAMILY SSF46689 1 91 5.73E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2182 87b1af23ef6668d646f8444296db6639 100 Pfam PF01527 Transposase 2 64 6.8E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Spica_1324 87b1af23ef6668d646f8444296db6639 100 SUPERFAMILY SSF46689 1 91 5.73E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1324 87b1af23ef6668d646f8444296db6639 100 Pfam PF01527 Transposase 2 64 6.8E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Pfam PF13432 Tetratricopeptide repeat 36 82 9.2E-6 T 13-10-2018 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Pfam PF13432 Tetratricopeptide repeat 252 303 8.3E-4 T 13-10-2018 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Pfam PF13432 Tetratricopeptide repeat 142 203 4.5E-7 T 13-10-2018 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Pfam PF04471 Restriction endonuclease 339 449 5.4E-10 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SUPERFAMILY SSF48452 37 312 2.66E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Gene3D G3DSA:1.25.40.10 169 318 5.4E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SUPERFAMILY SSF52980 342 454 2.41E-9 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Gene3D G3DSA:1.25.40.10 36 92 3.5E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SMART SM00028 135 168 1.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SMART SM00028 276 309 0.23 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SMART SM00028 237 270 9.5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SMART SM00028 169 202 0.096 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 SMART SM00028 203 235 190.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1174 bba7a16803865d9501ae3eaaab2be0bc 461 Gene3D G3DSA:1.25.40.10 99 168 1.0E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0928 47a540c106906f5fccf431c396add955 294 Pfam PF04539 Sigma-70 region 3 140 215 1.1E-11 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 84 97 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 SUPERFAMILY SSF88946 20 129 2.83E-42 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 Pfam PF04545 Sigma-70, region 4 229 282 1.0E-16 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 Gene3D G3DSA:1.10.10.10 211 294 2.2E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0928 47a540c106906f5fccf431c396add955 294 PIRSF PIRSF000770 1 291 5.1E-36 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 SUPERFAMILY SSF88659 133 207 2.88E-7 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0928 47a540c106906f5fccf431c396add955 294 Gene3D G3DSA:1.10.10.10 133 210 5.4E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0928 47a540c106906f5fccf431c396add955 294 SUPERFAMILY SSF88659 195 292 7.48E-25 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0928 47a540c106906f5fccf431c396add955 294 Gene3D G3DSA:1.10.601.10 2 129 1.8E-39 T 13-10-2018 Spica_0928 47a540c106906f5fccf431c396add955 294 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 254 280 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 56 282 9.4E-36 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 Pfam PF04542 Sigma-70 region 2 61 128 9.3E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 Pfam PF00140 Sigma-70 factor, region 1.2 24 55 2.4E-12 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_0928 47a540c106906f5fccf431c396add955 294 PRINTS PR00046 Major sigma-70 factor signature 233 245 4.0E-24 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 PRINTS PR00046 Major sigma-70 factor signature 108 116 4.0E-24 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 PRINTS PR00046 Major sigma-70 factor signature 254 269 4.0E-24 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 PRINTS PR00046 Major sigma-70 factor signature 84 97 4.0E-24 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_0928 47a540c106906f5fccf431c396add955 294 PRINTS PR00046 Major sigma-70 factor signature 269 280 4.0E-24 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_2164 f26935bc19225ef5ade8587798ac186d 345 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 13 342 1.1E-99 T 13-10-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 Spica_2164 f26935bc19225ef5ade8587798ac186d 345 Pfam PF03601 Conserved hypothetical protein 698 14 323 6.2E-95 T 13-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 20 462 4.6E-158 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 Pfam PF00156 Phosphoribosyl transferase domain 296 392 6.6E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 19 461 46.824 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 Pfam PF13537 Glutamine amidotransferase domain 101 220 6.0E-20 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 Gene3D G3DSA:3.60.20.10 20 462 7.9E-155 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 SUPERFAMILY SSF56235 20 249 7.72E-72 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 PIRSF PIRSF000485 16 469 1.0E-171 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 SUPERFAMILY SSF53271 257 467 1.84E-67 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_2414 62d9609118f5a9e51f7c4a55811cbe53 469 Gene3D G3DSA:3.40.50.2020 281 445 7.9E-155 T 13-10-2018 Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 1 152 2.0E-51 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 Gene3D G3DSA:3.90.45.10 1 161 2.4E-59 T 13-10-2018 IPR036821 Peptide deformylase superfamily Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 Pfam PF01327 Polypeptide deformylase 2 148 1.8E-50 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 PRINTS PR01576 Peptide deformylase signature 85 96 6.7E-38 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 PRINTS PR01576 Peptide deformylase signature 30 59 6.7E-38 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 PRINTS PR01576 Peptide deformylase signature 97 115 6.7E-38 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 PRINTS PR01576 Peptide deformylase signature 116 145 6.7E-38 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 PIRSF PIRSF004749 1 161 1.7E-53 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 Hamap MF_00163 Peptide deformylase [def]. 2 158 28.792 T 13-10-2018 IPR023635 Peptide deformylase Spica_2334 7ad79654fe450b8bc649f25e6a6baac6 161 SUPERFAMILY SSF56420 2 153 1.44E-55 T 13-10-2018 IPR036821 Peptide deformylase superfamily Spica_0145 b5718f26ccc81cbbd343498106035e27 501 Pfam PF05193 Peptidase M16 inactive domain 201 395 8.8E-14 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Spica_0145 b5718f26ccc81cbbd343498106035e27 501 Gene3D G3DSA:3.30.830.10 273 455 2.4E-18 T 13-10-2018 Spica_0145 b5718f26ccc81cbbd343498106035e27 501 Pfam PF00675 Insulinase (Peptidase family M16) 47 192 8.8E-21 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Spica_0145 b5718f26ccc81cbbd343498106035e27 501 Gene3D G3DSA:3.30.830.10 30 250 1.6E-53 T 13-10-2018 Spica_0145 b5718f26ccc81cbbd343498106035e27 501 SUPERFAMILY SSF63411 34 254 1.37E-49 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_0145 b5718f26ccc81cbbd343498106035e27 501 SUPERFAMILY SSF63411 276 456 2.44E-13 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_2043 ef9bf691d3bba718308843d75536730f 264 Pfam PF01039 Carboxyl transferase domain 38 213 1.3E-16 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Spica_2043 ef9bf691d3bba718308843d75536730f 264 SUPERFAMILY SSF52096 6 256 9.64E-74 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_2043 ef9bf691d3bba718308843d75536730f 264 Gene3D G3DSA:3.90.226.10 5 257 7.5E-80 T 13-10-2018 Spica_2043 ef9bf691d3bba718308843d75536730f 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 175 192 8.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 104 118 8.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 138 156 8.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 226 235 8.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 204 215 8.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 5 257 1.7E-98 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2043 ef9bf691d3bba718308843d75536730f 264 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 256 36.095 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Pfam PF02310 B12 binding domain 788 882 3.4E-21 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 TIGRFAM TIGR02082 metH: methionine synthase 12 1241 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:3.20.20.330 1 340 4.7E-118 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:3.20.20.20 341 642 8.3E-117 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SUPERFAMILY SSF47644 668 754 2.09E-26 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:1.10.1240.10 664 752 5.6E-37 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SMART SM01018 672 755 2.3E-41 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:3.10.196.10 948 1264 1.5E-122 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SUPERFAMILY SSF56507 943 1265 2.35E-107 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:3.40.50.280 785 935 1.8E-53 T 13-10-2018 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SUPERFAMILY SSF82282 10 400 1.18E-106 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 PIRSF PIRSF000381 1 1244 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Pfam PF02607 B12 binding domain 674 748 3.9E-26 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SUPERFAMILY SSF52242 784 934 4.58E-46 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Pfam PF02574 Homocysteine S-methyltransferase 16 324 5.7E-74 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 SUPERFAMILY SSF51717 357 630 2.09E-77 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Gene3D G3DSA:1.10.288.10 977 1141 1.5E-122 T 13-10-2018 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Pfam PF00809 Pterin binding enzyme 361 598 4.0E-48 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_2832 32a8985512f47ba87e5b3cc42bd81ab1 1270 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 979 1257 7.6E-107 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 221 335 6.0E-12 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 TIGRFAM TIGR03297 Ppyr-DeCO2ase: phosphonopyruvate decarboxylase 15 364 5.3E-120 T 13-10-2018 IPR017684 Phosphonopyruvate decarboxylase GO:0032923|GO:0033980 KEGG: 00440+4.1.1.82|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7510|MetaCyc: PWY-7769 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 SUPERFAMILY SSF52518 183 357 4.21E-26 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 148 2.1E-7 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 234 253 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 SUPERFAMILY SSF52518 8 151 2.09E-14 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 Gene3D G3DSA:3.40.50.970 176 362 1.4E-24 T 13-10-2018 Spica_1332 7fbd4ae1884c87734a0257f8a8a74da3 366 Gene3D G3DSA:3.40.50.970 7 174 1.2E-9 T 13-10-2018 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 SMART SM00491 350 472 1.8E-5 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 SMART SM00487 33 214 5.2E-5 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 SUPERFAMILY SSF52540 31 175 1.4E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 Gene3D G3DSA:3.40.50.300 323 498 1.7E-11 T 13-10-2018 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 Gene3D G3DSA:3.40.50.300 28 188 4.2E-15 T 13-10-2018 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 Pfam PF13307 Helicase C-terminal domain 375 472 5.2E-9 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 Pfam PF04851 Type III restriction enzyme, res subunit 37 165 3.6E-10 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spica_1786 fe8e1b1a7dda5ec3cce9524c29455dbc 825 SUPERFAMILY SSF52540 85 466 1.52E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 5 477 74.537 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 288 300 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 SUPERFAMILY SSF51412 3 468 1.31E-116 T 13-10-2018 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 Pfam PF00571 CBS domain 94 137 3.1E-9 T 13-10-2018 IPR000644 CBS domain Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 Pfam PF00571 CBS domain 146 195 9.0E-6 T 13-10-2018 IPR000644 CBS domain Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 PIRSF PIRSF000130 1 478 2.0E-189 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 SUPERFAMILY SSF54631 91 198 2.27E-27 T 13-10-2018 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 5 445 2.4E-173 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 SMART SM01240 4 464 3.4E-262 T 13-10-2018 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 464 9.5E-150 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 SMART SM00116 93 141 4.1E-6 T 13-10-2018 IPR000644 CBS domain Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 SMART SM00116 153 201 0.0091 T 13-10-2018 IPR000644 CBS domain Spica_1849 c7ddb70a9f9bd04ea34a6cbfb9f9ae6e 478 Gene3D G3DSA:3.20.20.70 1 477 2.0E-194 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 6 176 4.1E-85 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 SUPERFAMILY SSF56235 3 176 5.9E-60 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 Pfam PF00227 Proteasome subunit 5 174 1.0E-26 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 Gene3D G3DSA:3.60.20.10 2 177 1.4E-67 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 5 176 41.346 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Spica_1675 e25ea8fe92810f77b045b89b3587e7de 177 PIRSF PIRSF039093 1 177 4.5E-88 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 SUPERFAMILY SSF53822 68 348 6.21E-45 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 Pfam PF13377 Periplasmic binding protein-like domain 175 346 9.8E-29 T 13-10-2018 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 SUPERFAMILY SSF47413 6 64 5.34E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 1.3E-17 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 Gene3D G3DSA:3.40.50.2300 82 338 8.1E-55 T 13-10-2018 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 Gene3D G3DSA:3.40.50.2300 164 342 8.1E-55 T 13-10-2018 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 Gene3D G3DSA:1.10.260.40 1 64 2.3E-23 T 13-10-2018 Spica_2118 29bc42aa5b4477a97d9269991beb4f62 352 SMART SM00354 7 78 1.3E-23 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2852 78778fd4dc3de18d39ff8b57180a048d 315 PIRSF PIRSF002849 1 308 3.6E-112 T 13-10-2018 Spica_2852 78778fd4dc3de18d39ff8b57180a048d 315 SUPERFAMILY SSF52540 14 292 4.33E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2852 78778fd4dc3de18d39ff8b57180a048d 315 Gene3D G3DSA:3.40.50.300 4 200 5.2E-40 T 13-10-2018 Spica_2852 78778fd4dc3de18d39ff8b57180a048d 315 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 173 2.6E-57 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spica_2852 78778fd4dc3de18d39ff8b57180a048d 315 Gene3D G3DSA:1.10.8.300 204 299 6.7E-23 T 13-10-2018 Spica_1837 fb3e77252f2203aec05dc05db92685be 191 SUPERFAMILY SSF57802 148 191 1.52E-12 T 13-10-2018 Spica_1837 fb3e77252f2203aec05dc05db92685be 191 Gene3D G3DSA:2.20.28.10 147 191 9.7E-22 T 13-10-2018 Spica_1837 fb3e77252f2203aec05dc05db92685be 191 Gene3D G3DSA:1.20.1260.10 1 146 6.0E-60 T 13-10-2018 IPR012347 Ferritin-like Spica_1837 fb3e77252f2203aec05dc05db92685be 191 SUPERFAMILY SSF47240 4 147 1.76E-40 T 13-10-2018 IPR009078 Ferritin-like superfamily Spica_1837 fb3e77252f2203aec05dc05db92685be 191 Pfam PF02915 Rubrerythrin 11 138 1.7E-31 T 13-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 Gene3D G3DSA:2.40.500.20 91 208 6.7E-49 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.4E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.4E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 1.4E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 1.4E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.4E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 PIRSF PIRSF000349 1 208 1.5E-83 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 Gene3D G3DSA:1.10.287.990 20 90 4.1E-31 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 1.9E-42 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 1.4E-27 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 SUPERFAMILY SSF54719 94 202 2.36E-46 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0304 a6793039e2f7a98ff06773530ca36b30 208 SUPERFAMILY SSF46609 1 91 3.54E-34 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 Gene3D G3DSA:3.20.20.70 17 264 6.2E-77 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 105 123 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 SUPERFAMILY SSF51395 23 329 8.42E-72 T 13-10-2018 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 Pfam PF01207 Dihydrouridine synthase (Dus) 25 320 1.4E-79 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 14 331 1.4E-109 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 Gene3D G3DSA:1.10.1200.80 267 333 5.4E-10 T 13-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 Spica_0163 8f421c2e76b1a567442f49896eab8d86 333 PIRSF PIRSF006621 11 333 1.2E-82 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82693 40 127 1.66E-17 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.70.1430 564 670 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.70.1440 671 865 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82714 185 264 3.66E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 2.0E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:1.20.1640.10 11 505 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.70.1430 40 815 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82866 293 489 1.57E-39 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82693 561 659 4.34E-9 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.70.1320 134 324 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.2090.10 718 807 6.8E-262 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:1.20.1640.10 506 1020 6.8E-262 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Gene3D G3DSA:3.30.2090.10 180 271 6.8E-262 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82693 138 324 2.3E-12 T 13-10-2018 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 Pfam PF00873 AcrB/AcrD/AcrF family 4 1021 1.8E-218 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_2023 e44c8f060231eb60f8b1215c1ea2a1c0 1032 SUPERFAMILY SSF82866 805 1026 4.58E-42 T 13-10-2018 Spica_1547 d2fc8cf4917392f93d90106b96068df7 388 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 38 323 1.0E-78 T 13-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Spica_1547 d2fc8cf4917392f93d90106b96068df7 388 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 20 364 6.8E-135 T 13-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 SUPERFAMILY SSF54292 2 77 1.97E-20 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 SUPERFAMILY SSF47741 84 149 1.96E-6 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 Gene3D G3DSA:3.10.20.30 1 76 1.5E-22 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 Gene3D G3DSA:1.10.150.120 78 154 1.5E-5 T 13-10-2018 Spica_1450 660ca1e324af586503d6d0c83ec47db3 161 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 36 88 8.0E-7 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Spica_0099 561c209d4a0b2eca766aaf2e71730f41 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 34 9.9E-7 T 13-10-2018 Spica_0099 561c209d4a0b2eca766aaf2e71730f41 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 63 3.5E-7 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_0099 561c209d4a0b2eca766aaf2e71730f41 94 SUPERFAMILY SSF143120 1 36 4.71E-6 T 13-10-2018 IPR036165 YefM-like superfamily Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 Gene3D G3DSA:3.40.50.300 1 243 1.2E-56 T 13-10-2018 Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 SUPERFAMILY SSF52540 5 228 1.36E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 Pfam PF00005 ABC transporter 280 437 2.2E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 SMART SM00382 289 506 0.0042 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 SMART SM00382 30 220 1.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 SUPERFAMILY SSF52540 254 496 8.19E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 Pfam PF00005 ABC transporter 21 172 1.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 Gene3D G3DSA:3.40.50.300 252 507 3.6E-42 T 13-10-2018 Spica_2008 115f9b4b6ffcde0df7b6b00803d4b76d 508 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 Pfam PF04055 Radical SAM superfamily 75 233 3.0E-20 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 251 331 1.3E-6 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 Gene3D G3DSA:3.20.20.70 28 369 2.5E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 SUPERFAMILY SSF102114 48 318 3.14E-52 T 13-10-2018 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 SMART SM00729 71 281 7.5E-24 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 PIRSF PIRSF004762 25 339 6.8E-57 T 13-10-2018 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 SMART SM00876 247 340 0.0027 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Spica_1875 abc2a368be483f83b7a64a6e3c5544b1 377 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 50 361 7.8E-99 T 13-10-2018 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM Spica_1170 ca82442a3c1bc13ffa171cdd845dc768 297 Pfam PF04389 Peptidase family M28 80 236 4.5E-8 T 13-10-2018 IPR007484 Peptidase M28 Spica_1170 ca82442a3c1bc13ffa171cdd845dc768 297 SUPERFAMILY SSF53187 78 168 6.57E-12 T 13-10-2018 Spica_1170 ca82442a3c1bc13ffa171cdd845dc768 297 Gene3D G3DSA:3.40.630.10 55 292 2.4E-13 T 13-10-2018 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 6.0E-7 T 13-10-2018 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 26.329 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.9E-35 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.9E-35 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.9E-35 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 SUPERFAMILY SSF74731 3 116 5.23E-43 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 Gene3D G3DSA:1.10.1900.20 56 118 6.2E-27 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 Gene3D G3DSA:1.10.720.90 2 55 2.6E-19 T 13-10-2018 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 Pfam PF00453 Ribosomal protein L20 3 108 2.5E-43 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1699 7289a82d6183a6cd3fcac69291f32537 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.1E-48 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 Pfam PF02541 Ppx/GppA phosphatase family 32 310 3.0E-25 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 Gene3D G3DSA:3.30.420.40 10 308 1.1E-50 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 Pfam PF01966 HD domain 343 460 9.2E-12 T 13-10-2018 IPR006674 HD domain Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 SUPERFAMILY SSF53067 143 311 2.24E-15 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 Gene3D G3DSA:1.10.3210.10 327 513 3.4E-50 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 Gene3D G3DSA:3.30.420.150 116 301 1.1E-50 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 SUPERFAMILY SSF109604 329 511 1.41E-45 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 SUPERFAMILY SSF53067 9 130 3.15E-25 T 13-10-2018 Spica_2588 89091bd3066c78ad5f9f18a659b306cf 513 SMART SM00471 337 470 0.002 T 13-10-2018 IPR003607 HD/PDEase domain Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 Pfam PF00574 Clp protease 33 203 4.2E-65 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 Gene3D G3DSA:3.90.226.10 17 205 8.9E-60 T 13-10-2018 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 SUPERFAMILY SSF52096 32 204 6.22E-55 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 123 136 - T 13-10-2018 IPR033135 ClpP, histidine active site Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 PRINTS PR00127 Clp protease catalytic subunit P signature 179 198 2.9E-30 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 PRINTS PR00127 Clp protease catalytic subunit P signature 31 46 2.9E-30 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 PRINTS PR00127 Clp protease catalytic subunit P signature 70 90 2.9E-30 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 PRINTS PR00127 Clp protease catalytic subunit P signature 101 118 2.9E-30 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 PRINTS PR00127 Clp protease catalytic subunit P signature 122 141 2.9E-30 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_2494 423b5f9855f7cc96dadb7a9cbb1e9f0c 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 204 34.303 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_0770 2da4424e9a60cc98de1b745d18500170 293 Pfam PF02811 PHP domain 10 104 7.5E-8 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_0770 2da4424e9a60cc98de1b745d18500170 293 SMART SM00481 9 74 1.4E-17 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_0770 2da4424e9a60cc98de1b745d18500170 293 SUPERFAMILY SSF89550 8 265 1.7E-41 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_0770 2da4424e9a60cc98de1b745d18500170 293 Gene3D G3DSA:3.20.20.140 9 254 3.8E-77 T 13-10-2018 Spica_0770 2da4424e9a60cc98de1b745d18500170 293 Gene3D G3DSA:1.10.150.650 102 173 3.8E-77 T 13-10-2018 Spica_1009 2035286e21f018e388a56d8124d19b7d 340 Gene3D G3DSA:3.40.50.1820 5 338 4.5E-85 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_1009 2035286e21f018e388a56d8124d19b7d 340 SUPERFAMILY SSF53474 7 337 3.16E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_1009 2035286e21f018e388a56d8124d19b7d 340 Pfam PF05448 Acetyl xylan esterase (AXE1) 4 339 4.0E-117 T 13-10-2018 IPR008391 Acetyl xylan esterase Spica_1394 07c7d903a61a3fc4ede7aad7d302ac1a 360 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 23 354 3.9E-72 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Spica_1394 07c7d903a61a3fc4ede7aad7d302ac1a 360 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 15 354 28.914 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Spica_1394 07c7d903a61a3fc4ede7aad7d302ac1a 360 Gene3D G3DSA:1.10.8.1150 55 125 2.8E-8 T 13-10-2018 Spica_1394 07c7d903a61a3fc4ede7aad7d302ac1a 360 Pfam PF02618 YceG-like family 60 348 2.8E-70 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Pfam PF01769 Divalent cation transporter 320 450 6.9E-30 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Gene3D G3DSA:1.25.60.10 2 127 1.5E-22 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SUPERFAMILY SSF158791 6 129 1.03E-26 T 13-10-2018 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SUPERFAMILY SSF54631 131 265 2.65E-32 T 13-10-2018 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Gene3D G3DSA:3.10.580.10 128 255 4.0E-44 T 13-10-2018 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 TIGRFAM TIGR00400 mgtE: magnesium transporter 3 459 3.5E-122 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SMART SM00116 203 251 1.2E-8 T 13-10-2018 IPR000644 CBS domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SMART SM00116 139 192 38.0 T 13-10-2018 IPR000644 CBS domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Gene3D G3DSA:1.10.357.20 271 457 4.4E-57 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Pfam PF03448 MgtE intracellular N domain 30 129 2.3E-24 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SMART SM00924 29 132 7.9E-27 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 SUPERFAMILY SSF161093 277 457 5.23E-49 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Pfam PF00571 CBS domain 197 250 2.2E-7 T 13-10-2018 IPR000644 CBS domain Spica_2475 2c05d1c3a4ff0dd0a336b3c6255c33f0 459 Pfam PF00571 CBS domain 132 188 9.0E-7 T 13-10-2018 IPR000644 CBS domain Spica_2065 ce0ddd966a64e22a30cd122763d03e3c 354 Gene3D G3DSA:3.30.565.10 213 354 4.8E-8 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0511 affd47f887c56228a1cd7f754b7c8511 389 SUPERFAMILY SSF53756 3 383 1.07E-91 T 13-10-2018 Spica_0511 affd47f887c56228a1cd7f754b7c8511 389 Gene3D G3DSA:3.40.50.2000 191 356 4.6E-85 T 13-10-2018 Spica_0511 affd47f887c56228a1cd7f754b7c8511 389 Gene3D G3DSA:3.40.50.2000 5 365 4.6E-85 T 13-10-2018 Spica_0511 affd47f887c56228a1cd7f754b7c8511 389 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 4 369 2.3E-138 T 13-10-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_0511 affd47f887c56228a1cd7f754b7c8511 389 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 370 7.8E-87 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 SUPERFAMILY SSF103491 6 419 3.4E-110 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 Gene3D G3DSA:1.10.3370.10 4 425 4.0E-146 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 308 330 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 362 380 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 1.2E-92 T 13-10-2018 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 Pfam PF00344 SecY translocase 75 413 2.2E-107 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 418 1.2E-116 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 429 28.173 T 13-10-2018 IPR026593 Protein translocase subunit SecY Spica_0405 49472bb2cc6fbc19b69195bc7953959b 439 PIRSF PIRSF004557 2 435 4.5E-119 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 234 367 1.9E-9 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 Pfam PF13177 DNA polymerase III, delta subunit 20 176 4.7E-44 T 13-10-2018 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 356 9.9E-132 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 Gene3D G3DSA:1.10.8.60 11 238 1.8E-98 T 13-10-2018 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 SMART SM00382 37 179 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 SUPERFAMILY SSF48019 243 362 1.19E-13 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 SUPERFAMILY SSF52540 34 223 5.86E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 Gene3D G3DSA:3.40.50.300 13 177 1.8E-98 T 13-10-2018 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.4E-5 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_0203 fda12d692e006fbf8dee61494f9e3ade 634 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.4E-5 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 SUPERFAMILY SSF54893 1 93 7.98E-31 T 13-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 Gene3D G3DSA:3.30.70.140 1 93 3.3E-29 T 13-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 2 90 1.5E-29 T 13-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 4 92 2.0E-24 T 13-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 Gene3D G3DSA:2.30.30.20 94 144 1.5E-11 T 13-10-2018 Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 95 141 3.7E-14 T 13-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal Spica_2550 747f6fba9931c489deaa2849fbf963fb 144 SUPERFAMILY SSF57825 94 141 2.75E-14 T 13-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 1.1E-47 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 PIRSF PIRSF002191 1 129 3.0E-49 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 Gene3D G3DSA:2.30.30.790 5 117 4.4E-16 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.562 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 PRINTS PR00061 Ribosomal protein L19 signature 87 112 2.2E-39 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 PRINTS PR00061 Ribosomal protein L19 signature 3 32 2.2E-39 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 PRINTS PR00061 Ribosomal protein L19 signature 33 62 2.2E-39 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 Pfam PF01245 Ribosomal protein L19 4 111 2.1E-47 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0485 a094ef0b84a3b026393ffad91c6bcd3b 129 SUPERFAMILY SSF50104 1 119 5.01E-46 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Gene3D G3DSA:2.30.42.20 444 610 1.3E-39 T 13-10-2018 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 9 614 21.328 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 SMART SM01340 224 342 1.8E-30 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Gene3D G3DSA:3.30.565.10 10 219 2.1E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 SUPERFAMILY SSF118116 441 613 1.11E-33 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Pfam PF08676 MutL C terminal dimerisation domain 443 574 1.5E-28 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 241 340 2.1E-23 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Gene3D G3DSA:3.30.1370.100 481 570 1.3E-39 T 13-10-2018 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Gene3D G3DSA:3.30.230.10 233 341 4.8E-22 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 SMART SM00853 442 575 3.7E-33 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 101 107 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 126 1.0E-10 T 13-10-2018 Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 SUPERFAMILY SSF54211 205 341 3.41E-23 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1640 3174adb61846f9e0dae328c1e5ff3920 618 SUPERFAMILY SSF55874 9 224 8.12E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1123 a2ecd8657e0145a49bbe85bfcf2086b6 364 Pfam PF07238 PilZ domain 244 360 2.0E-13 T 13-10-2018 IPR009875 PilZ domain GO:0035438 Spica_1123 a2ecd8657e0145a49bbe85bfcf2086b6 364 Pfam PF12945 Flagellar protein YcgR 160 225 1.1E-5 T 13-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal Spica_1123 a2ecd8657e0145a49bbe85bfcf2086b6 364 Gene3D G3DSA:2.40.10.220 256 363 1.9E-5 T 13-10-2018 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01182 Ornithine decarboxylase signature 25 49 2.2E-20 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01182 Ornithine decarboxylase signature 51 78 2.2E-20 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01182 Ornithine decarboxylase signature 125 147 2.2E-20 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01182 Ornithine decarboxylase signature 95 119 2.2E-20 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01182 Ornithine decarboxylase signature 330 340 2.2E-20 T 13-10-2018 IPR002433 Ornithine decarboxylase GO:0006596 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 215 228 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 SUPERFAMILY SSF50621 245 388 7.53E-32 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 SUPERFAMILY SSF51419 24 272 5.82E-64 T 13-10-2018 IPR029066 PLP-binding barrel Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 269 1.1E-52 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 Gene3D G3DSA:2.40.37.10 24 381 2.5E-93 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 Gene3D G3DSA:3.20.20.10 32 272 2.5E-93 T 13-10-2018 IPR029066 PLP-binding barrel Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 4.7E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 260 279 4.7E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 4.7E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 176 189 4.7E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_0659 27902ba75fd6176fa1f5fecbe47b6f9d 390 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 270 366 4.6E-13 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Pfam PF02833 DHHA2 domain 422 543 2.9E-16 T 13-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Gene3D G3DSA:3.10.310.20 429 546 2.4E-28 T 13-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Gene3D G3DSA:3.10.580.10 78 294 3.1E-49 T 13-10-2018 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Gene3D G3DSA:3.90.1640.10 3 77 8.2E-17 T 13-10-2018 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Pfam PF00571 CBS domain 75 114 2.2E-4 T 13-10-2018 IPR000644 CBS domain Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Pfam PF00571 CBS domain 263 305 4.4E-5 T 13-10-2018 IPR000644 CBS domain Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 SMART SM01131 420 545 4.1E-28 T 13-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 SUPERFAMILY SSF54631 69 127 1.97E-6 T 13-10-2018 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Gene3D G3DSA:3.90.1640.10 295 427 8.2E-39 T 13-10-2018 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Gene3D G3DSA:3.40.1390.20 130 249 3.1E-49 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Pfam PF01368 DHH family 5 385 5.7E-26 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 Pfam PF07085 DRTGG domain 143 246 6.7E-16 T 13-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 SUPERFAMILY SSF54631 257 305 1.85E-7 T 13-10-2018 Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 SUPERFAMILY SSF75138 140 253 8.24E-17 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2491 3a94e073b9fdd16a8b0be1ecd9e8c628 549 SUPERFAMILY SSF64182 3 544 1.47E-60 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 Gene3D G3DSA:3.30.70.580 8 126 1.2E-27 T 13-10-2018 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 Gene3D G3DSA:3.30.70.660 127 266 1.3E-40 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 Pfam PF01416 tRNA pseudouridine synthase 15 124 9.7E-8 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 Pfam PF01416 tRNA pseudouridine synthase 164 264 9.7E-24 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 264 30.954 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 PIRSF PIRSF001430 9 266 4.4E-70 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 SUPERFAMILY SSF55120 9 265 4.46E-69 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0494 1d9a59c344b3c8f82785453dc36e065e 266 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 11 259 2.1E-51 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 Pfam PF00571 CBS domain 5 54 5.5E-7 T 13-10-2018 IPR000644 CBS domain Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 SUPERFAMILY SSF54631 6 57 8.12E-8 T 13-10-2018 Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 Gene3D G3DSA:3.90.550.10 131 357 3.6E-55 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 Pfam PF00483 Nucleotidyl transferase 133 354 1.6E-30 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 SUPERFAMILY SSF53448 49 352 1.95E-54 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 SMART SM00116 7 55 0.0094 T 13-10-2018 IPR000644 CBS domain Spica_0512 1c0c929efc361c0f14f39d1bf541aed7 359 Gene3D G3DSA:3.10.580.10 1 117 2.2E-15 T 13-10-2018 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 173 232 4.1E-17 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 SUPERFAMILY SSF81301 5 142 1.2E-41 T 13-10-2018 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 293 437 2.4E-16 T 13-10-2018 IPR032810 CCA-adding enzyme, C-terminal Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 SUPERFAMILY SSF81891 143 443 1.57E-59 T 13-10-2018 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 Gene3D G3DSA:3.30.460.10 5 144 6.5E-51 T 13-10-2018 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 Pfam PF01743 Poly A polymerase head domain 24 145 4.9E-37 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 TIGRFAM TIGR00277 HDIG: HDIG domain 254 314 1.5E-8 T 13-10-2018 IPR006675 HDIG domain Spica_1403 ce74f32f380f179c538f1b191116dcaf 449 Gene3D G3DSA:1.10.3090.10 145 438 1.2E-60 T 13-10-2018 Spica_2653 21f26715649ce9382550adcc9643e438 100 SUPERFAMILY SSF48295 11 92 1.2E-17 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Spica_2653 21f26715649ce9382550adcc9643e438 100 Pfam PF01371 Trp repressor protein 11 93 1.1E-17 T 13-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 Spica_2653 21f26715649ce9382550adcc9643e438 100 Gene3D G3DSA:1.10.1270.10 5 97 1.2E-19 T 13-10-2018 IPR038116 TrpR-like superfamily Spica_2653 21f26715649ce9382550adcc9643e438 100 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 27 92 9.0E-8 T 13-10-2018 IPR013335 Trp repressor, bacterial GO:0006355 Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 7.4E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 7.4E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 SUPERFAMILY SSF46785 8 82 3.43E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 SMART SM00345 19 78 1.0E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 Gene3D G3DSA:1.10.10.10 12 131 4.8E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1655 d6d7323b1a31495a9a8fbf51d8e620ba 328 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 3.4E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 Gene3D G3DSA:3.20.20.80 1 446 1.2E-168 T 13-10-2018 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 437 9.5E-177 T 13-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 13-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 SUPERFAMILY SSF51445 5 445 1.23E-162 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 Pfam PF00232 Glycosyl hydrolase family 1 5 442 2.4E-159 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 381 1.4E-21 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 345 353 1.4E-21 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 284 298 1.4E-21 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 427 1.4E-21 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0975 b8f5665e1057325c1ce84d3572cd0e17 446 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 408 1.4E-21 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 Spica_0537 c40ddc93c1678fdb4be0df63e081e533 562 Pfam PF07510 Protein of unknown function (DUF1524) 415 549 1.7E-27 T 13-10-2018 IPR011089 Domain of unknown function DUF1524 Spica_0537 c40ddc93c1678fdb4be0df63e081e533 562 Pfam PF03235 Protein of unknown function DUF262 15 235 9.9E-37 T 13-10-2018 IPR004919 Domain of unknown function DUF262 Spica_0393 2bc572071ca3ae5b98ca7ba8b1d6bb1e 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 59 13.662 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0393 2bc572071ca3ae5b98ca7ba8b1d6bb1e 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 58 8.0E-12 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0393 2bc572071ca3ae5b98ca7ba8b1d6bb1e 65 Gene3D G3DSA:1.10.287.310 1 64 2.8E-16 T 13-10-2018 Spica_0393 2bc572071ca3ae5b98ca7ba8b1d6bb1e 65 Pfam PF00831 Ribosomal L29 protein 5 58 5.7E-16 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0393 2bc572071ca3ae5b98ca7ba8b1d6bb1e 65 SUPERFAMILY SSF46561 5 61 5.63E-15 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 168 289 1.7E-16 T 13-10-2018 IPR000014 PAS domain Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Gene3D G3DSA:3.30.450.20 159 288 7.0E-22 T 13-10-2018 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SMART SM00388 318 411 1.6E-5 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SUPERFAMILY SSF47384 312 411 6.28E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SUPERFAMILY SSF55874 401 565 8.77E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SUPERFAMILY SSF55785 157 280 4.71E-19 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SMART SM00387 452 566 1.7E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SMART SM00086 240 282 3.9E-5 T 13-10-2018 IPR001610 PAC motif Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 SMART SM00091 170 239 9.1E-4 T 13-10-2018 IPR000014 PAS domain Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 522 1.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 1.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 563 1.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 1.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 563 6.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Pfam PF00512 His Kinase A (phospho-acceptor) domain 319 411 9.5E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Gene3D G3DSA:1.10.287.130 295 406 3.8E-23 T 13-10-2018 Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Gene3D G3DSA:3.30.565.10 415 568 9.8E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0694 80d4ac9775eefd44bd25b3a624da9b20 573 Pfam PF13426 PAS domain 181 281 7.3E-13 T 13-10-2018 IPR000014 PAS domain Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.5E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.5E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.5E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 SUPERFAMILY SSF51735 2 250 1.15E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 Pfam PF00106 short chain dehydrogenase 10 205 9.6E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_0233 4a85d32f7366436f4dc0a11f8a7d5bc4 251 Gene3D G3DSA:3.40.50.720 4 251 6.8E-40 T 13-10-2018 Spica_1266 05ccf6407800872f875474cf30772aa8 492 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 486 1.7E-160 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Spica_1266 05ccf6407800872f875474cf30772aa8 492 Gene3D G3DSA:3.40.50.2000 3 485 7.6E-171 T 13-10-2018 Spica_1266 05ccf6407800872f875474cf30772aa8 492 SUPERFAMILY SSF53756 3 489 4.71E-113 T 13-10-2018 Spica_1266 05ccf6407800872f875474cf30772aa8 492 Pfam PF08323 Starch synthase catalytic domain 2 245 6.3E-73 T 13-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Spica_1266 05ccf6407800872f875474cf30772aa8 492 Pfam PF00534 Glycosyl transferases group 1 302 445 3.5E-10 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_1266 05ccf6407800872f875474cf30772aa8 492 Hamap MF_00484 Glycogen synthase [glgA]. 1 487 40.569 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 Spica_1266 05ccf6407800872f875474cf30772aa8 492 Gene3D G3DSA:3.40.50.2000 258 471 7.6E-171 T 13-10-2018 Spica_1088 d2d37a36c1852c1f7ffe39d655492efc 420 Gene3D G3DSA:1.10.3210.10 8 293 1.9E-65 T 13-10-2018 Spica_1088 d2d37a36c1852c1f7ffe39d655492efc 420 Pfam PF01966 HD domain 56 131 9.3E-6 T 13-10-2018 IPR006674 HD domain Spica_1088 d2d37a36c1852c1f7ffe39d655492efc 420 SMART SM00471 52 188 1.3E-5 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1088 d2d37a36c1852c1f7ffe39d655492efc 420 SUPERFAMILY SSF109604 9 329 2.27E-63 T 13-10-2018 Spica_1452 d97c4248762a5ea6202700701e4699b5 198 Gene3D G3DSA:1.10.10.10 3 105 5.4E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1452 d97c4248762a5ea6202700701e4699b5 198 SUPERFAMILY SSF46785 18 87 9.24E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1452 d97c4248762a5ea6202700701e4699b5 198 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 66 1.7E-6 T 13-10-2018 Spica_1291 13ce82416d2ad7cd9d75e584f3952e06 278 Gene3D G3DSA:3.40.830.10 2 278 7.5E-31 T 13-10-2018 Spica_1291 13ce82416d2ad7cd9d75e584f3952e06 278 Pfam PF01875 Memo-like protein 12 275 2.0E-27 T 13-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Spica_1291 13ce82416d2ad7cd9d75e584f3952e06 278 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 4 276 2.2E-57 T 13-10-2018 Spica_0348 1124d403392fe88a4b4d92aed177c6fe 221 Pfam PF01728 FtsJ-like methyltransferase 19 218 4.8E-43 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Spica_0348 1124d403392fe88a4b4d92aed177c6fe 221 Gene3D G3DSA:3.40.50.150 18 220 6.1E-45 T 13-10-2018 Spica_0348 1124d403392fe88a4b4d92aed177c6fe 221 PIRSF PIRSF005461 1 221 2.3E-54 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Spica_0348 1124d403392fe88a4b4d92aed177c6fe 221 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 3 220 25.137 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Spica_0348 1124d403392fe88a4b4d92aed177c6fe 221 SUPERFAMILY SSF53335 18 220 1.33E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 SUPERFAMILY SSF54862 140 191 1.6E-13 T 13-10-2018 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Gene3D G3DSA:3.20.20.20 36 101 4.5E-12 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 SUPERFAMILY SSF54862 217 266 1.2E-14 T 13-10-2018 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Pfam PF00037 4Fe-4S binding domain 239 260 2.8E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Pfam PF00037 4Fe-4S binding domain 164 185 2.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 97 2.0E-25 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 246 257 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Gene3D G3DSA:3.30.70.20 205 268 2.2E-13 T 13-10-2018 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Gene3D G3DSA:3.30.70.20 133 194 7.8E-15 T 13-10-2018 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Pfam PF04060 Putative Fe-S cluster 44 76 7.6E-12 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 Spica_0646 8bda1ea4dd0a63e446cdfe2941a5803a 288 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 5 192 27.967 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 Spica_2321 76044d31de20825d9d11c46063b20469 514 SMART SM00387 394 505 2.4E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2321 76044d31de20825d9d11c46063b20469 514 Gene3D G3DSA:1.10.287.130 234 346 3.8E-7 T 13-10-2018 Spica_2321 76044d31de20825d9d11c46063b20469 514 Pfam PF06580 Histidine kinase 300 376 2.0E-23 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_2321 76044d31de20825d9d11c46063b20469 514 SUPERFAMILY SSF55874 354 503 1.05E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2321 76044d31de20825d9d11c46063b20469 514 Gene3D G3DSA:3.30.565.10 364 507 3.4E-20 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2321 76044d31de20825d9d11c46063b20469 514 SMART SM00304 236 288 1.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2321 76044d31de20825d9d11c46063b20469 514 SUPERFAMILY SSF158472 236 283 1.7E-7 T 13-10-2018 Spica_2321 76044d31de20825d9d11c46063b20469 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 502 1.5E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2321 76044d31de20825d9d11c46063b20469 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 480 8.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2321 76044d31de20825d9d11c46063b20469 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 502 8.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2321 76044d31de20825d9d11c46063b20469 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 8.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2271 37f9146a0a25fd1427e011c077a65e14 141 SUPERFAMILY SSF88723 10 128 3.05E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2271 37f9146a0a25fd1427e011c077a65e14 141 Pfam PF01850 PIN domain 11 132 5.0E-15 T 13-10-2018 IPR002716 PIN domain Spica_2271 37f9146a0a25fd1427e011c077a65e14 141 Gene3D G3DSA:3.40.50.1010 7 135 4.3E-13 T 13-10-2018 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Gene3D G3DSA:3.40.50.300 122 300 1.1E-63 T 13-10-2018 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 121 3.7E-12 T 13-10-2018 IPR000014 PAS domain Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Gene3D G3DSA:1.10.8.60 301 380 4.7E-29 T 13-10-2018 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 464 1.5E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 444 1.5E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Pfam PF13426 PAS domain 11 113 2.8E-13 T 13-10-2018 IPR000014 PAS domain Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 SUPERFAMILY SSF46689 343 463 1.02E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 SUPERFAMILY SSF52540 131 373 4.26E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 SMART SM00091 1 65 5.1E-5 T 13-10-2018 IPR000014 PAS domain Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 SUPERFAMILY SSF55785 5 109 1.92E-18 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Gene3D G3DSA:1.10.10.60 410 466 2.5E-17 T 13-10-2018 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 343 352 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 SMART SM00382 150 293 5.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Gene3D G3DSA:3.30.450.20 2 121 2.6E-19 T 13-10-2018 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Pfam PF00158 Sigma-54 interaction domain 131 296 5.1E-68 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_0707 9fdc35697fb3461cfd4778aafb6f8ecb 470 Pfam PF02954 Bacterial regulatory protein, Fis family 422 461 4.4E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1138 f8a08dcc9a32d62e1cf895c77367f2c2 315 SUPERFAMILY SSF110997 243 311 9.55E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Spica_1138 f8a08dcc9a32d62e1cf895c77367f2c2 315 Pfam PF05036 Sporulation related domain 246 309 9.8E-8 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Spica_1138 f8a08dcc9a32d62e1cf895c77367f2c2 315 SUPERFAMILY SSF48452 53 179 6.64E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1138 f8a08dcc9a32d62e1cf895c77367f2c2 315 Gene3D G3DSA:1.25.40.10 33 145 9.1E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1138 f8a08dcc9a32d62e1cf895c77367f2c2 315 Gene3D G3DSA:3.30.70.1070 247 314 2.1E-6 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 Gene3D G3DSA:2.60.98.20 168 346 1.6E-9 T 13-10-2018 IPR037058 Flagellar hook protein FlgE superfamily Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 387 464 3.2E-21 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 Pfam PF07559 Flagellar basal body protein FlaE 200 346 3.0E-17 T 13-10-2018 IPR011491 Flagellar hook protein FlgE Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 SUPERFAMILY SSF117143 92 426 4.45E-68 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 447 7.2E-87 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1537 c4d9daf0c3754a88afbd0e72f5a39cab 466 Pfam PF00460 Flagella basal body rod protein 5 35 2.6E-10 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Spica_0899 2a3c16e5384d2268ace7dd0a057b11fb 418 Gene3D G3DSA:3.30.470.20 101 416 1.1E-74 T 13-10-2018 Spica_0899 2a3c16e5384d2268ace7dd0a057b11fb 418 SMART SM01209 108 288 2.3E-4 T 13-10-2018 Spica_0899 2a3c16e5384d2268ace7dd0a057b11fb 418 SUPERFAMILY SSF56059 96 329 1.67E-38 T 13-10-2018 Spica_0899 2a3c16e5384d2268ace7dd0a057b11fb 418 Pfam PF13535 ATP-grasp domain 143 290 7.7E-23 T 13-10-2018 Spica_1894 5d63ca6b5c011ff0f56ec88dae1d79b9 285 Gene3D G3DSA:3.20.20.190 10 285 1.4E-68 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Spica_1894 5d63ca6b5c011ff0f56ec88dae1d79b9 285 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 278 5.4E-45 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spica_1894 5d63ca6b5c011ff0f56ec88dae1d79b9 285 SUPERFAMILY SSF51695 16 284 1.74E-63 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Spica_0737 0ff5d268a28df725b7db5f9b3a488c43 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 285 5.6E-8 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0737 0ff5d268a28df725b7db5f9b3a488c43 297 SUPERFAMILY SSF161098 49 283 5.76E-49 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0737 0ff5d268a28df725b7db5f9b3a488c43 297 Gene3D G3DSA:1.10.3720.10 45 293 7.4E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 SUPERFAMILY SSF50443 331 496 8.37E-72 T 13-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 Pfam PF11762 L-arabinose isomerase C-terminal domain 363 476 9.2E-52 T 13-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 SUPERFAMILY SSF53743 5 328 2.88E-112 T 13-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 Pfam PF02610 L-arabinose isomerase 6 360 4.9E-173 T 13-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 PIRSF PIRSF001478 2 499 5.8E-242 T 13-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 Gene3D G3DSA:3.40.50.10940 3 176 1.6E-77 T 13-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 6 305 2.0E-102 T 13-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 Spica_2819 271b852e0de74c9ddde0d28d643fb03c 499 Hamap MF_00519 L-arabinose isomerase [araA]. 2 477 63.512 T 13-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 314 1.2E-58 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 611 635 - T 13-10-2018 IPR001455 TusA-like domain Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF55424 333 456 1.39E-31 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 4.3E-13 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.3E-13 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 4.3E-13 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 4.3E-13 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Gene3D G3DSA:3.50.50.60 3 350 9.0E-176 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Gene3D G3DSA:3.30.110.40 606 679 1.3E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Gene3D G3DSA:3.40.1260.10 706 863 4.2E-64 T 13-10-2018 IPR027396 DsrEFH-like Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF64307 608 678 1.44E-16 T 13-10-2018 IPR036868 TusA-like domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF52821 445 557 5.89E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.6E-22 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.6E-22 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.6E-22 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.6E-22 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.6E-22 T 13-10-2018 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF75169 713 861 1.0E-20 T 13-10-2018 IPR027396 DsrEFH-like Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Pfam PF01206 Sulfurtransferase TusA 611 678 8.4E-18 T 13-10-2018 IPR001455 TusA-like domain Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Gene3D G3DSA:3.50.50.60 115 450 9.0E-176 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Pfam PF13686 DsrE/DsrF/DrsH-like family 712 862 7.2E-57 T 13-10-2018 IPR032836 DsrE2-like family Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF51905 151 321 8.3E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 441 6.3E-13 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SUPERFAMILY SSF51905 2 198 1.8E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Gene3D G3DSA:3.40.250.10 461 560 7.9E-25 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 Pfam PF00581 Rhodanese-like domain 467 554 3.6E-13 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_1545 3aa7135c0d53b5add17c3fccb09cc986 863 SMART SM00450 462 558 2.5E-23 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SUPERFAMILY SSF55785 249 341 4.01E-12 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SUPERFAMILY SSF55785 120 251 3.14E-13 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Pfam PF13188 PAS domain 133 180 3.4E-7 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Pfam PF13188 PAS domain 260 329 1.1E-7 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Gene3D G3DSA:3.30.450.20 123 255 8.0E-17 T 13-10-2018 Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 260 2.6E-8 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 288 379 3.2E-9 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Pfam PF07568 Histidine kinase 392 436 5.9E-10 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SUPERFAMILY SSF52172 2 136 2.56E-24 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SMART SM00091 258 332 0.85 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SMART SM00091 132 197 2.2E-6 T 13-10-2018 IPR000014 PAS domain Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Gene3D G3DSA:3.40.50.2300 2 122 1.5E-21 T 13-10-2018 Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Pfam PF00072 Response regulator receiver domain 5 110 1.3E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 Gene3D G3DSA:3.30.450.20 256 371 4.5E-23 T 13-10-2018 Spica_2748 8158dafe3fb6a93aaa31eb9bca706309 437 SMART SM00448 2 114 8.4E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1076 85824992229978347259b83d115e5c58 311 Pfam PF04754 Putative transposase, YhgA-like 4 200 5.2E-29 T 13-10-2018 IPR006842 Transposase (putative), YhgA-like Spica_1076 85824992229978347259b83d115e5c58 311 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 5 311 1.5E-22 T 13-10-2018 IPR010106 Recombination-promoting nuclease RpnA Spica_0444 b7dbcb8b674e4017f866111f18f225fb 516 SUPERFAMILY SSF51445 3 511 2.25E-163 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0444 b7dbcb8b674e4017f866111f18f225fb 516 Gene3D G3DSA:3.20.20.80 1 513 8.8E-187 T 13-10-2018 Spica_0444 b7dbcb8b674e4017f866111f18f225fb 516 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 2 512 7.5E-111 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spica_0444 b7dbcb8b674e4017f866111f18f225fb 516 Pfam PF02446 4-alpha-glucanotransferase 9 491 8.0E-158 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 Gene3D G3DSA:1.10.40.50 271 335 1.2E-16 T 13-10-2018 Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 Pfam PF03193 RsgA GTPase 94 268 4.1E-49 T 13-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 72 329 3.2E-62 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 SUPERFAMILY SSF52540 111 333 3.5E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 Gene3D G3DSA:3.40.50.300 97 269 7.1E-47 T 13-10-2018 Spica_1163 0a0ee2a262d49ed670757ac6496bb790 335 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 1 335 28.465 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 Gene3D G3DSA:3.40.50.12160 2 117 1.8E-18 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 Gene3D G3DSA:3.80.30.20 163 392 6.0E-71 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 168 188 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 421 2.7E-126 T 13-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 SUPERFAMILY SSF102114 163 382 7.72E-49 T 13-10-2018 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 SMART SM00729 164 378 4.6E-44 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 Pfam PF00919 Uncharacterized protein family UPF0004 4 91 2.8E-22 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 416 3.4E-95 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Spica_1151 ccf362ee777b1e917dbee7ec97b7d291 476 Pfam PF04055 Radical SAM superfamily 170 335 1.7E-24 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 Pfam PF00005 ABC transporter 20 168 4.0E-37 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 SUPERFAMILY SSF52540 5 238 5.46E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 Gene3D G3DSA:3.40.50.300 2 242 1.3E-80 T 13-10-2018 Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 SMART SM00382 29 216 2.2E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 PIRSF PIRSF039085 1 243 1.3E-112 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Spica_2620 a7fbedc76163248a4362ed26668f0d1c 243 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0920 88ac15da3db8937eee57b51a8d4bd72f 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 338 6.7E-45 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1552 a85d2e3992312a079956c58a9a8279fc 277 Gene3D G3DSA:3.30.950.10 121 238 2.9E-39 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Spica_1552 a85d2e3992312a079956c58a9a8279fc 277 SUPERFAMILY SSF53790 4 229 1.13E-56 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Spica_1552 a85d2e3992312a079956c58a9a8279fc 277 Gene3D G3DSA:3.40.1010.10 3 120 6.3E-33 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Spica_1552 a85d2e3992312a079956c58a9a8279fc 277 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 214 1.1E-10 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Gene3D G3DSA:1.10.10.60 435 500 4.3E-10 T 13-10-2018 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 SMART SM00065 9 156 1.5E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Gene3D G3DSA:3.40.50.300 169 351 6.7E-66 T 13-10-2018 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 SUPERFAMILY SSF52540 180 421 7.23E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 204 217 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 393 402 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 SUPERFAMILY SSF55781 11 158 1.0E-18 T 13-10-2018 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 SUPERFAMILY SSF46689 393 498 1.48E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Pfam PF13185 GAF domain 9 146 9.9E-13 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Pfam PF00158 Sigma-54 interaction domain 180 347 2.0E-68 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 SMART SM00382 200 343 4.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 266 281 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Gene3D G3DSA:3.30.450.40 4 168 3.3E-15 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0709 ac8f788985d09a3363aa04d379cc16e9 500 Gene3D G3DSA:1.10.8.60 353 427 4.0E-24 T 13-10-2018 Spica_0231 a217e56dbc664ae39ff28ee52ce9a6b6 129 Gene3D G3DSA:3.30.1460.10 36 117 4.9E-8 T 13-10-2018 Spica_0231 a217e56dbc664ae39ff28ee52ce9a6b6 129 SUPERFAMILY SSF69635 36 110 1.2E-12 T 13-10-2018 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 SUPERFAMILY SSF100950 80 233 5.34E-10 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 SMART SM00420 6 58 4.8E-17 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.2E-16 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 SMART SM01134 71 232 2.3E-26 T 13-10-2018 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 Pfam PF00455 DeoR C terminal sensor domain 80 231 6.6E-29 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 SUPERFAMILY SSF46785 5 62 5.0E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.1E-9 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_2816 ec063f4f5fa9edba20d038cd7b088821 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.1E-9 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_1244 ab985f37c3f68276daed59ef12ce1d9b 235 Gene3D G3DSA:3.90.850.10 10 234 4.2E-80 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Spica_1244 ab985f37c3f68276daed59ef12ce1d9b 235 SUPERFAMILY SSF56529 12 231 1.57E-71 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Spica_1244 ab985f37c3f68276daed59ef12ce1d9b 235 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 19 230 8.4E-68 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 58 5.0E-13 T 13-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 61 117 1.2E-17 T 13-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 SUPERFAMILY SSF47979 61 116 2.67E-16 T 13-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 SMART SM00529 22 119 1.5E-37 T 13-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 SUPERFAMILY SSF46785 1 60 1.47E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 Gene3D G3DSA:1.10.10.10 2 65 4.3E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1557 c06158f1fef52e3a70421ba1f68f2782 120 Gene3D G3DSA:1.10.60.10 66 120 4.0E-22 T 13-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 Spica_1220 0d2993eab70bdec85e95d6144850d538 368 SMART SM00257 133 177 6.7E-12 T 13-10-2018 IPR018392 LysM domain Spica_1220 0d2993eab70bdec85e95d6144850d538 368 SMART SM00257 183 226 3.4E-9 T 13-10-2018 IPR018392 LysM domain Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Pfam PF01551 Peptidase family M23 267 362 6.2E-30 T 13-10-2018 IPR016047 Peptidase M23 Spica_1220 0d2993eab70bdec85e95d6144850d538 368 SUPERFAMILY SSF51261 134 366 1.41E-52 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Gene3D G3DSA:2.70.70.10 228 368 2.3E-45 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Gene3D G3DSA:3.10.350.10 183 226 2.5E-10 T 13-10-2018 IPR036779 LysM domain superfamily Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Pfam PF01476 LysM domain 184 226 7.0E-10 T 13-10-2018 IPR018392 LysM domain Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Pfam PF01476 LysM domain 134 177 2.7E-12 T 13-10-2018 IPR018392 LysM domain Spica_1220 0d2993eab70bdec85e95d6144850d538 368 Gene3D G3DSA:3.10.350.10 130 182 1.2E-13 T 13-10-2018 IPR036779 LysM domain superfamily Spica_2314 e6c104f5ad93609b2eba75751362fb3b 408 Pfam PF01882 Protein of unknown function DUF58 195 277 7.0E-5 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 810 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 648 660 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 SUPERFAMILY SSF53756 2 814 4.4E-301 T 13-10-2018 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 Pfam PF00343 Carbohydrate phosphorylase 93 810 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 Gene3D G3DSA:3.40.50.2000 462 795 0.0 T 13-10-2018 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 Gene3D G3DSA:3.40.50.2000 19 812 0.0 T 13-10-2018 Spica_2809 694943db5abc71e5d271edacc0e33fb8 816 PIRSF PIRSF000460 1 816 7.3E-228 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 Spica_1558 9f3a022fcd90f0aeddb527b2a069cc8f 178 SUPERFAMILY SSF52540 3 178 1.62E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1558 9f3a022fcd90f0aeddb527b2a069cc8f 178 Gene3D G3DSA:3.40.50.300 3 178 9.4E-39 T 13-10-2018 Spica_1558 9f3a022fcd90f0aeddb527b2a069cc8f 178 PIRSF PIRSF006135 1 178 2.0E-34 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 Spica_1558 9f3a022fcd90f0aeddb527b2a069cc8f 178 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 177 6.2E-38 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SUPERFAMILY SSF47384 500 576 7.06E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Gene3D G3DSA:3.30.450.20 347 483 5.2E-15 T 13-10-2018 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 628 738 7.9E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Gene3D G3DSA:3.30.565.10 583 745 1.3E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SMART SM00388 510 580 8.5E-5 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 705 723 4.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 702 4.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 688 4.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SUPERFAMILY SSF103190 58 184 2.86E-9 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SUPERFAMILY SSF55785 351 463 3.77E-9 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Pfam PF14827 Double sensory domain of two-component sensor kinase 43 215 4.5E-20 T 13-10-2018 IPR029150 Double Cache domain 3 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SMART SM00387 623 744 6.8E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Pfam PF00512 His Kinase A (phospho-acceptor) domain 510 577 6.3E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 Gene3D G3DSA:1.10.287.130 503 577 3.2E-14 T 13-10-2018 Spica_0967 8881c885d7e737a601b6ac556a4c0c11 751 SUPERFAMILY SSF55874 577 742 3.01E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 74 107 1.7E-6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 40 73 0.058 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 244 277 1.9E-7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 142 175 9.9E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 312 345 0.0012 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 414 447 100.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 210 243 1.9E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 108 141 1.0E-6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 346 379 0.48 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 176 209 1.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 380 413 44.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SMART SM00028 448 481 16.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SUPERFAMILY SSF48452 337 472 9.86E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SUPERFAMILY SSF48452 11 241 6.64E-48 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Gene3D G3DSA:1.25.40.10 2 109 1.5E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF14559 Tetratricopeptide repeat 20 75 1.7E-7 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF14559 Tetratricopeptide repeat 428 480 1.5E-6 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF14559 Tetratricopeptide repeat 360 423 4.0E-6 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Gene3D G3DSA:1.25.40.10 110 244 6.2E-38 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF13431 Tetratricopeptide repeat 131 161 6.7E-5 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF13414 TPR repeat 83 121 1.7E-11 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Gene3D G3DSA:1.25.40.10 245 536 4.1E-53 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF00515 Tetratricopeptide repeat 244 277 2.6E-8 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF13432 Tetratricopeptide repeat 184 243 2.7E-9 T 13-10-2018 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 SUPERFAMILY SSF48452 207 382 1.74E-39 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2727 8f1d0533447567fc780d36a62cb51359 1004 Pfam PF07719 Tetratricopeptide repeat 315 345 2.0E-5 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 SUPERFAMILY SSF82693 39 122 1.2E-10 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.70.1430 38 767 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Pfam PF00873 AcrB/AcrD/AcrF family 634 968 3.6E-39 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Pfam PF00873 AcrB/AcrD/AcrF family 38 461 1.2E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 SUPERFAMILY SSF82866 290 470 3.14E-16 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:1.20.1640.10 488 968 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 SUPERFAMILY SSF82693 141 304 1.36E-7 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.70.1440 626 817 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 SUPERFAMILY SSF82714 178 258 3.66E-8 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.2090.10 175 266 1.1E-128 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.70.1320 127 316 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 SUPERFAMILY SSF82866 754 973 2.49E-28 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.70.1430 546 625 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:1.20.1640.10 317 487 1.1E-128 T 13-10-2018 Spica_1066 46281297d41872cc3295de12b8e9a71e 994 Gene3D G3DSA:3.30.2090.10 675 759 1.1E-128 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_2818 0db5f1ad2530ebedd94fe7f8b256214b 233 SMART SM01007 9 199 1.1E-54 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal Spica_2818 0db5f1ad2530ebedd94fe7f8b256214b 233 SUPERFAMILY SSF53639 5 224 1.96E-58 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Spica_2818 0db5f1ad2530ebedd94fe7f8b256214b 233 Gene3D G3DSA:3.40.225.10 4 232 1.0E-52 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Spica_2818 0db5f1ad2530ebedd94fe7f8b256214b 233 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 198 3.4E-41 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal Spica_1885 52eebeab84adf910d255f21433524b8f 370 Gene3D G3DSA:3.40.50.720 130 305 1.3E-139 T 13-10-2018 Spica_1885 52eebeab84adf910d255f21433524b8f 370 SMART SM01003 4 137 2.4E-69 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spica_1885 52eebeab84adf910d255f21433524b8f 370 Gene3D G3DSA:3.40.50.720 3 353 1.3E-139 T 13-10-2018 Spica_1885 52eebeab84adf910d255f21433524b8f 370 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Spica_1885 52eebeab84adf910d255f21433524b8f 370 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.7E-43 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spica_1885 52eebeab84adf910d255f21433524b8f 370 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.7E-83 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spica_1885 52eebeab84adf910d255f21433524b8f 370 PIRSF PIRSF000183 1 370 7.2E-159 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Spica_1885 52eebeab84adf910d255f21433524b8f 370 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 5.8E-154 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Spica_1885 52eebeab84adf910d255f21433524b8f 370 SUPERFAMILY SSF52283 1 359 9.35E-61 T 13-10-2018 Spica_1885 52eebeab84adf910d255f21433524b8f 370 SMART SM01002 149 297 3.1E-84 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spica_1885 52eebeab84adf910d255f21433524b8f 370 SUPERFAMILY SSF51735 137 303 5.76E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0953 e242c343842c32f72bdf1ad1975a0821 162 Pfam PF00710 Asparaginase, N-terminal 4 153 7.8E-24 T 13-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 Spica_0953 e242c343842c32f72bdf1ad1975a0821 162 SUPERFAMILY SSF53774 1 154 4.71E-35 T 13-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 Spica_0953 e242c343842c32f72bdf1ad1975a0821 162 PRINTS PR00139 Asparaginase/glutaminase family signature 75 93 1.3E-6 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Spica_0953 e242c343842c32f72bdf1ad1975a0821 162 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.3E-6 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 Spica_0953 e242c343842c32f72bdf1ad1975a0821 162 Gene3D G3DSA:3.40.50.1170 3 159 1.4E-29 T 13-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 SMART SM00359 2 91 0.0019 T 13-10-2018 IPR002478 PUA domain GO:0003723 Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 221 383 2.5E-21 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 Gene3D G3DSA:3.40.50.150 220 431 2.9E-72 T 13-10-2018 Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 SUPERFAMILY SSF53335 83 427 3.01E-63 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 Gene3D G3DSA:2.30.130.10 2 75 1.1E-20 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 Spica_2586 18e5ed809ba3cfc40bea66b89bd1c6f4 432 SUPERFAMILY SSF88697 1 74 4.72E-12 T 13-10-2018 IPR015947 PUA-like superfamily Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Gene3D G3DSA:3.30.230.10 214 372 1.9E-39 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 253 266 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 400 414 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 41 56 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 75 88 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 110 124 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 540 556 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 480 497 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 462 478 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR00418 DNA topoisomerase II family signature 500 512 2.3E-49 T 13-10-2018 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 SUPERFAMILY SSF56719 376 596 1.2E-57 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 ProSitePatterns PS00177 DNA topoisomerase II signature. 402 410 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 SUPERFAMILY SSF54211 221 365 1.12E-35 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Pfam PF01751 Toprim domain 400 504 2.5E-10 T 13-10-2018 IPR006171 TOPRIM domain Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR01159 DNA gyrase subunit B signature 288 304 2.5E-7 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR01159 DNA gyrase subunit B signature 7 17 2.5E-7 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR01159 DNA gyrase subunit B signature 336 350 2.5E-7 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 PRINTS PR01159 DNA gyrase subunit B signature 575 591 2.5E-7 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Gene3D G3DSA:3.30.565.10 10 212 6.4E-55 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 SUPERFAMILY SSF55874 7 206 4.89E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 172 1.2E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 SMART SM00387 37 173 5.5E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 SMART SM00433 41 599 7.8E-172 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Pfam PF00204 DNA gyrase B 220 360 2.4E-32 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 537 594 5.2E-7 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Spica_1624 c5cd15c43ae733fb35bc7b24f206ab88 603 Gene3D G3DSA:3.40.50.670 377 602 1.9E-63 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SMART SM00304 296 348 2.1E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SUPERFAMILY SSF158472 298 345 7.45E-11 T 13-10-2018 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 557 3.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 524 3.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 3.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 3.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Gene3D G3DSA:3.30.565.10 431 580 3.2E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SMART SM00387 469 579 1.6E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SUPERFAMILY SSF47384 352 427 1.35E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Gene3D G3DSA:1.10.287.130 362 425 6.1E-9 T 13-10-2018 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SMART SM00388 358 429 9.5E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Gene3D G3DSA:1.20.1480.50 262 354 4.5E-13 T 13-10-2018 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Pfam PF00672 HAMP domain 297 344 5.9E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 577 4.7E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 426 3.8E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2579 052542edf6c1e9c7c7ef7e474df7a3d1 582 SUPERFAMILY SSF55874 415 577 1.31E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2351 aac3ac48f0f81c6fb30110f98b1f750e 534 SUPERFAMILY SSF52540 286 503 3.31E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2351 aac3ac48f0f81c6fb30110f98b1f750e 534 Pfam PF00488 MutS domain V 332 463 2.1E-18 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_2351 aac3ac48f0f81c6fb30110f98b1f750e 534 Gene3D G3DSA:3.40.50.300 286 532 4.2E-36 T 13-10-2018 Spica_2351 aac3ac48f0f81c6fb30110f98b1f750e 534 SMART SM00534 329 500 1.7E-5 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 Pfam PF00717 Peptidase S24-like 123 188 7.9E-16 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 Hamap MF_00015 LexA repressor [lexA]. 3 203 31.068 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 SUPERFAMILY SSF46785 3 69 1.09E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 TIGRFAM TIGR00498 lexA: repressor LexA 1 202 1.2E-64 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 Gene3D G3DSA:2.10.109.10 87 202 6.8E-41 T 13-10-2018 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 Pfam PF01726 LexA DNA binding domain 1 64 1.0E-20 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 119 129 7.0E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 141 7.0E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 158 170 7.0E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 Gene3D G3DSA:1.10.10.10 1 69 2.3E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2581 af82d9966cbbdfac14e90a2314c87159 204 SUPERFAMILY SSF51306 81 201 2.79E-33 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Spica_1814 d4c8176afd0e04e096cbb9b79879f6f2 207 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 3 206 1.7E-40 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1814 d4c8176afd0e04e096cbb9b79879f6f2 207 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 207 19.578 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1814 d4c8176afd0e04e096cbb9b79879f6f2 207 Pfam PF01813 ATP synthase subunit D 12 201 1.9E-44 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1239 48ef499c3d5cd9719aba01d3436d58f2 241 SUPERFAMILY SSF52540 14 233 3.5E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1239 48ef499c3d5cd9719aba01d3436d58f2 241 Pfam PF00005 ABC transporter 33 181 5.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1239 48ef499c3d5cd9719aba01d3436d58f2 241 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1239 48ef499c3d5cd9719aba01d3436d58f2 241 SMART SM00382 42 232 7.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1239 48ef499c3d5cd9719aba01d3436d58f2 241 Gene3D G3DSA:3.40.50.300 12 234 3.0E-57 T 13-10-2018 Spica_1650 6fe6d1926a0cc9bcc63c371017cba00c 562 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 383 505 5.3E-32 T 13-10-2018 IPR025299 CstA, C-terminal domain Spica_1650 6fe6d1926a0cc9bcc63c371017cba00c 562 Pfam PF02554 Carbon starvation protein CstA 3 345 4.3E-108 T 13-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Gene3D G3DSA:3.30.450.20 23 75 7.5E-12 T 13-10-2018 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Pfam PF00672 HAMP domain 213 263 1.3E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 488 1.5E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Gene3D G3DSA:3.30.450.20 76 182 7.5E-12 T 13-10-2018 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Gene3D G3DSA:1.10.287.950 211 503 1.9E-68 T 13-10-2018 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 SMART SM00304 212 267 1.4E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 SMART SM00304 435 498 80.0 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 Pfam PF02743 Cache domain 3 163 3.8E-15 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 SUPERFAMILY SSF58104 241 504 3.53E-59 T 13-10-2018 Spica_1994 81840b186f11f9f619ca94b72a67b89b 506 SMART SM00283 268 501 2.0E-62 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 Gene3D G3DSA:3.30.1360.200 271 378 1.1E-22 T 13-10-2018 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 319 547 3.4E-73 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1832 36d2de452abbbb356f61f86825555b3b 573 Gene3D G3DSA:3.30.70.3400 137 233 9.9E-21 T 13-10-2018 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 Gene3D G3DSA:1.20.1640.10 399 552 7.1E-13 T 13-10-2018 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 137 553 2.4E-138 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 SUPERFAMILY SSF82866 364 554 3.66E-42 T 13-10-2018 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 567 38.11 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 PRINTS PR00702 Acriflavin resistance protein family signature 531 554 2.5E-7 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 PRINTS PR00702 Acriflavin resistance protein family signature 456 480 2.5E-7 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 PRINTS PR00702 Acriflavin resistance protein family signature 403 426 2.5E-7 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1832 36d2de452abbbb356f61f86825555b3b 573 Pfam PF02355 Protein export membrane protein 386 553 2.1E-19 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Gene3D G3DSA:3.30.870.10 493 679 8.3E-64 T 13-10-2018 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Pfam PF13089 Polyphosphate kinase N-terminal domain 8 112 1.9E-32 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Gene3D G3DSA:3.30.870.10 314 492 5.4E-72 T 13-10-2018 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 PIRSF PIRSF015589 1 688 2.3E-244 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Pfam PF13090 Polyphosphate kinase C-terminal domain 325 670 1.8E-149 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 SUPERFAMILY SSF143724 112 298 2.75E-41 T 13-10-2018 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 SUPERFAMILY SSF140356 7 106 4.32E-32 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 671 4.8E-237 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 SUPERFAMILY SSF56024 493 675 2.47E-63 T 13-10-2018 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 SUPERFAMILY SSF56024 308 487 7.85E-57 T 13-10-2018 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Pfam PF02503 Polyphosphate kinase middle domain 122 314 6.8E-46 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Gene3D G3DSA:3.30.1840.10 1 301 2.1E-86 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 Spica_2587 52a175cdbb7f2aeb3695679f8c6fbb66 697 Hamap MF_00347 Polyphosphate kinase [ppk]. 5 675 27.119 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Spica_1104 c520bde83e0bf8b769da42658f19040b 242 Pfam PF04055 Radical SAM superfamily 21 166 7.2E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1104 c520bde83e0bf8b769da42658f19040b 242 Gene3D G3DSA:3.20.20.70 2 228 5.8E-29 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1104 c520bde83e0bf8b769da42658f19040b 242 Pfam PF13394 4Fe-4S single cluster domain 25 105 7.5E-9 T 13-10-2018 Spica_1104 c520bde83e0bf8b769da42658f19040b 242 SUPERFAMILY SSF102114 14 207 1.57E-18 T 13-10-2018 Spica_1104 c520bde83e0bf8b769da42658f19040b 242 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 188 3.1E-47 T 13-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein Spica_1963 8d77963c53551c893418578335198af8 415 Gene3D G3DSA:3.30.70.270 247 415 1.3E-55 T 13-10-2018 Spica_1963 8d77963c53551c893418578335198af8 415 Pfam PF00990 Diguanylate cyclase, GGDEF domain 258 412 1.5E-47 T 13-10-2018 IPR000160 GGDEF domain Spica_1963 8d77963c53551c893418578335198af8 415 SUPERFAMILY SSF52172 1 104 9.25E-18 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1963 8d77963c53551c893418578335198af8 415 Gene3D G3DSA:3.40.50.2300 124 244 1.8E-20 T 13-10-2018 Spica_1963 8d77963c53551c893418578335198af8 415 SUPERFAMILY SSF55073 263 413 8.63E-47 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1963 8d77963c53551c893418578335198af8 415 SMART SM00448 131 241 1.9E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1963 8d77963c53551c893418578335198af8 415 SMART SM00448 2 114 0.0074 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1963 8d77963c53551c893418578335198af8 415 Gene3D G3DSA:3.40.50.2300 2 121 7.2E-16 T 13-10-2018 Spica_1963 8d77963c53551c893418578335198af8 415 SMART SM00267 247 415 4.4E-57 T 13-10-2018 IPR000160 GGDEF domain Spica_1963 8d77963c53551c893418578335198af8 415 Pfam PF00072 Response regulator receiver domain 133 241 7.4E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1963 8d77963c53551c893418578335198af8 415 Pfam PF00072 Response regulator receiver domain 4 104 1.5E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1963 8d77963c53551c893418578335198af8 415 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 414 2.0E-53 T 13-10-2018 IPR000160 GGDEF domain Spica_1963 8d77963c53551c893418578335198af8 415 SUPERFAMILY SSF52172 125 256 1.57E-22 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1259 fb55201d1aba971f876479b27adfb660 384 SUPERFAMILY SSF53756 2 380 2.93E-83 T 13-10-2018 Spica_1259 fb55201d1aba971f876479b27adfb660 384 Pfam PF13439 Glycosyltransferase Family 4 14 180 1.6E-37 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_1259 fb55201d1aba971f876479b27adfb660 384 Pfam PF00534 Glycosyl transferases group 1 194 359 5.3E-36 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_1259 fb55201d1aba971f876479b27adfb660 384 Gene3D G3DSA:3.40.50.2000 204 369 2.2E-37 T 13-10-2018 Spica_1259 fb55201d1aba971f876479b27adfb660 384 Gene3D G3DSA:3.40.50.2000 1 203 1.9E-48 T 13-10-2018 Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 Pfam PF00436 Single-strand binding protein family 4 105 3.0E-25 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 SUPERFAMILY SSF50249 4 122 4.11E-30 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 Gene3D G3DSA:2.40.50.140 1 125 1.6E-31 T 13-10-2018 Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 124 2.4E-25 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 PIRSF PIRSF002070 1 152 3.0E-27 T 13-10-2018 Spica_2050 f4616f120d63041888e6a64afd0a2a76 156 Hamap MF_00984 Single-stranded DNA-binding protein. 4 110 23.91 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Spica_0387 52be26badccd44d8a71d7ba731481655 94 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 93 18.855 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Spica_0387 52be26badccd44d8a71d7ba731481655 94 Gene3D G3DSA:3.30.70.330 1 94 3.4E-30 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_0387 52be26badccd44d8a71d7ba731481655 94 SUPERFAMILY SSF54189 3 92 1.4E-26 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0387 52be26badccd44d8a71d7ba731481655 94 Pfam PF00276 Ribosomal protein L23 5 89 9.5E-29 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 Gene3D G3DSA:3.40.50.1000 333 601 3.9E-75 T 13-10-2018 IPR023214 HAD superfamily Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 SUPERFAMILY SSF56784 351 649 9.22E-53 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 SUPERFAMILY SSF81653 153 250 1.44E-19 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 SUPERFAMILY SSF81665 94 642 9.02E-14 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 103 650 2.7E-160 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 123 631 8.1E-68 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 Gene3D G3DSA:3.40.1110.10 363 477 3.9E-75 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 354 360 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 Gene3D G3DSA:2.70.150.20 144 255 1.6E-25 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 Pfam PF00122 E1-E2 ATPase 151 332 1.5E-45 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 200 214 3.4E-20 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 352 366 3.4E-20 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 572 584 3.4E-20 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 548 567 3.4E-20 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 503 3.4E-20 T 13-10-2018 Spica_2262 64b6c1f05cb558e994d651796e256cd5 653 Pfam PF00702 haloacid dehalogenase-like hydrolase 351 561 9.9E-28 T 13-10-2018 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 SUPERFAMILY SSF55681 13 368 2.08E-116 T 13-10-2018 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 SUPERFAMILY SSF52954 352 458 3.02E-33 T 13-10-2018 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 11 457 50.675 T 13-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 13 233 2.8E-88 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 Gene3D G3DSA:3.30.930.10 14 362 3.7E-127 T 13-10-2018 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 33 47 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 310 322 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 132 144 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 185 202 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 212 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 153 170 2.7E-50 T 13-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 Pfam PF03129 Anticodon binding domain 366 454 3.0E-21 T 13-10-2018 IPR004154 Anticodon-binding Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 Gene3D G3DSA:3.40.50.800 363 462 1.4E-31 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Spica_0896 a05686fdfd0fcd51803a713bddd227e6 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 151 327 2.1E-11 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 430 525 3.7E-25 T 13-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 SUPERFAMILY SSF52540 203 526 2.84E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 Pfam PF13541 Subunit ChlI of Mg-chelatase 18 138 5.4E-41 T 13-10-2018 Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 3 525 3.1E-149 T 13-10-2018 IPR004482 Mg chelatase-related protein Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 Gene3D G3DSA:3.30.230.10 30 165 2.4E-14 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 Gene3D G3DSA:3.40.50.300 204 528 5.7E-48 T 13-10-2018 Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 SUPERFAMILY SSF54211 5 163 2.88E-33 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 SMART SM00382 223 413 6.3E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0769 dc5258471d25d0e17e79f534dc96d546 549 Pfam PF01078 Magnesium chelatase, subunit ChlI 203 411 1.5E-74 T 13-10-2018 IPR000523 Magnesium chelatase ChlI domain Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 112 126 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 PIRSF PIRSF001413 17 442 2.7E-119 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 84 423 1.8E-45 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 SUPERFAMILY SSF53686 39 435 4.85E-109 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 29 436 39.822 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 21 437 9.2E-190 T 13-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 PIRSF PIRSF500824 10 445 4.6E-199 T 13-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 Gene3D G3DSA:3.40.50.1100 22 247 3.6E-167 T 13-10-2018 Spica_2792 aabdcf323e68cadfa4892f7cc13b9c1a 469 Gene3D G3DSA:3.40.50.1100 21 429 3.6E-167 T 13-10-2018 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Gene3D G3DSA:2.60.40.1760 10 216 9.1E-12 T 13-10-2018 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Pfam PF01055 Glycosyl hydrolases family 31 236 671 8.9E-127 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Gene3D G3DSA:2.60.40.1180 596 667 6.9E-17 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 SUPERFAMILY SSF51011 587 666 1.29E-18 T 13-10-2018 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 SUPERFAMILY SSF74650 78 226 1.76E-8 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Gene3D G3DSA:3.20.20.80 420 595 2.9E-55 T 13-10-2018 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Gene3D G3DSA:3.20.20.80 256 419 4.6E-57 T 13-10-2018 Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 Gene3D G3DSA:2.60.40.1180 668 788 2.7E-10 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0072 acb1a67c7c8597c53d2438f5a9c51bb9 793 SUPERFAMILY SSF51445 245 581 3.42E-72 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0751 dc7e99d1b27e1e50ed9fdac19a69f96f 325 SUPERFAMILY SSF51735 1 322 4.85E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0751 dc7e99d1b27e1e50ed9fdac19a69f96f 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 251 2.1E-48 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Spica_0751 dc7e99d1b27e1e50ed9fdac19a69f96f 325 Gene3D G3DSA:3.90.25.10 172 305 2.9E-112 T 13-10-2018 Spica_0751 dc7e99d1b27e1e50ed9fdac19a69f96f 325 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 319 6.6E-109 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 Spica_0751 dc7e99d1b27e1e50ed9fdac19a69f96f 325 Gene3D G3DSA:3.40.50.720 3 251 2.9E-112 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 383 398 5.8E-5 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 97 117 5.8E-5 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 SUPERFAMILY SSF51230 85 123 1.73E-5 T 13-10-2018 IPR011053 Single hybrid motif Spica_2003 0df25bb9521064127fa1f547df05ffca 435 SUPERFAMILY SSF56954 140 221 2.88E-5 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Gene3D G3DSA:1.10.287.470 119 246 1.1E-46 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Gene3D G3DSA:2.40.420.20 70 417 1.1E-46 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Gene3D G3DSA:2.40.50.100 85 281 1.1E-46 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Pfam PF13437 HlyD family secretion protein 246 342 1.7E-11 T 13-10-2018 Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Pfam PF13533 Biotin-lipoyl like 89 128 5.7E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Spica_2003 0df25bb9521064127fa1f547df05ffca 435 Gene3D G3DSA:2.40.30.170 74 358 1.1E-46 T 13-10-2018 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 155 170 4.5E-31 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 53 68 4.5E-31 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 127 142 4.5E-31 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 87 99 4.5E-31 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 142 154 4.5E-31 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 SUPERFAMILY SSF50891 40 186 5.99E-55 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 SUPERFAMILY SSF54534 198 345 1.87E-42 T 13-10-2018 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 253 342 8.2E-29 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 40 178 3.2E-45 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 Gene3D G3DSA:2.40.100.10 38 185 2.9E-59 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 Gene3D G3DSA:3.10.50.40 206 345 3.5E-45 T 13-10-2018 Spica_0197 71e50bb694877fb7b683b0e44d8389a1 345 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 82 99 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Spica_0663 831569c6f9f81381f11cf41a2af3097d 227 SUPERFAMILY SSF53633 2 226 2.75E-32 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0663 831569c6f9f81381f11cf41a2af3097d 227 PIRSF PIRSF005650 1 227 1.9E-45 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Spica_0663 831569c6f9f81381f11cf41a2af3097d 227 Gene3D G3DSA:3.40.1160.10 3 227 1.8E-46 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0663 831569c6f9f81381f11cf41a2af3097d 227 Pfam PF00696 Amino acid kinase family 1 201 4.4E-23 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_0663 831569c6f9f81381f11cf41a2af3097d 227 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 4 226 3.1E-57 T 13-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Spica_1325 3ad386cb2d8a20f1028e85ac15a5f132 281 SUPERFAMILY SSF53098 110 271 3.29E-45 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_1325 3ad386cb2d8a20f1028e85ac15a5f132 281 Pfam PF00665 Integrase core domain 112 223 5.9E-26 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Spica_1325 3ad386cb2d8a20f1028e85ac15a5f132 281 Gene3D G3DSA:3.30.420.10 106 268 8.2E-19 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_1325 3ad386cb2d8a20f1028e85ac15a5f132 281 Pfam PF13276 HTH-like domain 33 89 1.8E-12 T 13-10-2018 IPR025948 HTH-like domain Spica_2381 ba3c4c0e780fe12aab7d7e7aab533dce 293 SUPERFAMILY SSF53300 73 189 8.01E-11 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2381 ba3c4c0e780fe12aab7d7e7aab533dce 293 Gene3D G3DSA:3.40.50.410 73 217 2.9E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2381 ba3c4c0e780fe12aab7d7e7aab533dce 293 Pfam PF01882 Protein of unknown function DUF58 37 120 1.6E-20 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 SUPERFAMILY SSF46689 325 376 3.76E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 Pfam PF12833 Helix-turn-helix domain 301 373 3.8E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 Gene3D G3DSA:3.40.50.2300 4 257 2.9E-65 T 13-10-2018 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 SUPERFAMILY SSF53822 7 287 4.71E-30 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 Gene3D G3DSA:1.10.10.60 274 378 3.7E-22 T 13-10-2018 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 Pfam PF13377 Periplasmic binding protein-like domain 99 265 5.7E-27 T 13-10-2018 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 326 368 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 Gene3D G3DSA:3.40.50.2300 89 265 2.9E-65 T 13-10-2018 Spica_2349 3036fd01e6eb4633d58b66e0ae5759b1 379 SMART SM00342 289 372 5.5E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Pfam PF08245 Mur ligase middle domain 126 307 4.1E-37 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Pfam PF01225 Mur ligase family, catalytic domain 33 114 5.9E-10 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 SUPERFAMILY SSF53244 333 461 1.21E-29 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 408 5.9E-12 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Gene3D G3DSA:3.40.1190.10 101 324 7.0E-54 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Gene3D G3DSA:3.90.190.20 330 467 8.8E-33 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 SUPERFAMILY SSF63418 6 117 2.49E-19 T 13-10-2018 IPR035911 MurE/MurF, N-terminal Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 36 461 4.1E-118 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Gene3D G3DSA:3.40.1390.10 5 83 2.8E-16 T 13-10-2018 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 7 464 28.49 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_1686 92dbfef7114d5c8b8a3550c0e8d3801c 468 SUPERFAMILY SSF53623 123 326 7.06E-42 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_2597 4a7e90222cc3eb27f94d75f7d6021e84 222 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 147 221 2.4E-14 T 13-10-2018 IPR006260 TonB/TolA, C-terminal Spica_2597 4a7e90222cc3eb27f94d75f7d6021e84 222 SUPERFAMILY SSF74653 125 221 2.35E-14 T 13-10-2018 Spica_2597 4a7e90222cc3eb27f94d75f7d6021e84 222 Gene3D G3DSA:3.30.1150.10 108 222 9.4E-19 T 13-10-2018 Spica_2597 4a7e90222cc3eb27f94d75f7d6021e84 222 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 144 220 1.3E-13 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 PIRSF PIRSF001084 1 663 2.5E-150 T 13-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 Gene3D G3DSA:3.40.50.880 397 626 1.3E-42 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 Pfam PF02449 Beta-galactosidase 10 375 2.4E-107 T 13-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 Gene3D G3DSA:3.20.20.80 1 390 2.3E-110 T 13-10-2018 Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 SUPERFAMILY SSF52317 396 624 5.49E-33 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 SUPERFAMILY SSF51445 6 375 1.24E-84 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0045 7c0091d3d1e92c5796b8336584df5258 675 Pfam PF08532 Beta-galactosidase trimerisation domain 399 624 3.0E-40 T 13-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 10 228 5.4E-68 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 227 5.8E-58 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 232 30.852 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 Gene3D G3DSA:3.40.50.1360 7 227 2.7E-72 T 13-10-2018 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 SUPERFAMILY SSF75445 137 213 5.23E-21 T 13-10-2018 Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 SUPERFAMILY SSF100950 1 155 2.09E-37 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_2326 d86cd117e8dd2e67ab272024640e2809 233 Gene3D G3DSA:3.30.70.260 133 211 2.7E-72 T 13-10-2018 Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 SUPERFAMILY SSF54211 88 184 1.52E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 179 1.8E-55 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 200 39.977 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 Gene3D G3DSA:3.30.230.40 91 200 8.1E-35 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 SUPERFAMILY SSF54211 3 86 8.47E-31 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2433 d59aaa52ea6ce7dce02ef07452b32c70 201 Gene3D G3DSA:3.30.230.40 1 90 5.5E-35 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Gene3D G3DSA:2.40.50.140 457 546 5.2E-23 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Gene3D G3DSA:2.40.50.140 370 456 4.8E-24 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Gene3D G3DSA:2.40.50.140 281 369 4.0E-28 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 21 122 5.88E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 359 449 3.28E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 21 535 1.4E-192 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 270 378 1.42E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Pfam PF00575 S1 RNA binding domain 461 535 1.5E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Pfam PF00575 S1 RNA binding domain 202 272 2.7E-17 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Pfam PF00575 S1 RNA binding domain 287 359 3.8E-17 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Pfam PF00575 S1 RNA binding domain 375 446 2.8E-15 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Pfam PF00575 S1 RNA binding domain 33 96 2.6E-7 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Gene3D G3DSA:2.40.50.140 199 280 2.1E-24 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 Gene3D G3DSA:2.40.50.140 22 110 1.6E-15 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 167 187 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 36 54 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 94 113 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 54 68 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 342 360 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 118 134 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 224 245 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PRINTS PR00681 Ribosomal protein S1 signature 302 321 2.9E-46 T 13-10-2018 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 441 554 1.86E-21 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 461 535 2.6E-22 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 34 97 7.0E-12 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 374 446 2.3E-20 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 287 359 1.2E-26 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 202 272 2.8E-26 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SMART SM00316 113 183 3.8 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PIRSF PIRSF002111 325 447 5.3E-45 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PIRSF PIRSF002111 412 566 4.3E-39 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 PIRSF PIRSF002111 2 350 1.7E-112 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 196 297 2.16E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1379 ddd2bd0df4eed31dea372df8018451e4 572 SUPERFAMILY SSF50249 117 197 3.86E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 Gene3D G3DSA:1.10.3810.10 54 252 5.6E-49 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 SUPERFAMILY SSF53955 47 269 6.47E-58 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 Pfam PF00912 Transglycosylase 81 236 7.2E-45 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 Gene3D G3DSA:3.40.710.10 269 652 8.0E-69 T 13-10-2018 Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 SUPERFAMILY SSF56601 218 654 3.47E-73 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 47 806 5.0E-194 T 13-10-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 717 803 1.1E-12 T 13-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2335 7b746a3460eb3dfdded79b21b208ed8a 810 Pfam PF00905 Penicillin binding protein transpeptidase domain 313 454 3.5E-8 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spica_0681 ae9a83d25dc77ab0c644d44bd16f10b8 548 Gene3D G3DSA:2.60.40.4070 209 278 3.1E-6 T 13-10-2018 Spica_0681 ae9a83d25dc77ab0c644d44bd16f10b8 548 Pfam PF13860 FlgD Ig-like domain 221 276 1.1E-6 T 13-10-2018 IPR025965 FlgD Ig-like domain Spica_0681 ae9a83d25dc77ab0c644d44bd16f10b8 548 Pfam PF08308 PEGA domain 43 105 3.4E-15 T 13-10-2018 IPR013229 PEGA Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Gene3D G3DSA:3.40.50.300 574 881 2.5E-97 T 13-10-2018 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Gene3D G3DSA:3.40.1170.10 1 113 3.2E-39 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 5 865 3.0E-266 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SUPERFAMILY SSF52540 573 803 1.33E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Pfam PF00488 MutS domain V 619 802 7.1E-82 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Pfam PF01624 MutS domain I 6 111 1.4E-35 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Gene3D G3DSA:1.10.1420.10 268 565 3.7E-86 T 13-10-2018 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 696 712 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Pfam PF05192 MutS domain III 272 565 1.2E-33 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SUPERFAMILY SSF53150 106 267 2.49E-35 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Gene3D G3DSA:1.10.1420.10 388 541 3.7E-86 T 13-10-2018 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SMART SM00534 615 800 1.5E-115 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 860 23.273 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SUPERFAMILY SSF55271 3 107 3.4E-35 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SUPERFAMILY SSF48334 269 571 9.02E-75 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Gene3D G3DSA:3.30.420.110 119 263 3.6E-32 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 PIRSF PIRSF037677 1 831 6.5E-153 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Pfam PF05188 MutS domain II 120 255 4.6E-24 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 SMART SM00533 286 597 1.9E-89 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Spica_1350 48b27a88e704d7f0a84b0e8d701b7ee5 890 Pfam PF05190 MutS family domain IV 434 524 2.1E-26 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 PIRSF PIRSF000116 202 331 9.0E-19 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 PIRSF PIRSF000116 4 207 2.5E-47 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 45.365 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 6.5E-76 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 2.3E-143 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 Gene3D G3DSA:1.10.3730.40 183 333 8.5E-72 T 13-10-2018 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 SUPERFAMILY SSF51735 4 183 5.07E-75 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 7.3E-69 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 Gene3D G3DSA:3.40.50.720 1 182 1.3E-81 T 13-10-2018 Spica_2676 5a85ce8d712e92eea79485d792fa6ad0 333 SUPERFAMILY SSF48179 184 329 2.04E-72 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SUPERFAMILY SSF55326 749 930 2.09E-24 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1208 1471 1.6E-85 T 13-10-2018 Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Gene3D G3DSA:3.90.650.10 514 693 7.1E-48 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Gene3D G3DSA:3.90.650.10 939 1123 8.8E-10 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SUPERFAMILY SSF55326 218 519 9.07E-27 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Pfam PF02769 AIR synthase related protein, C-terminal domain 526 678 8.2E-23 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Gene3D G3DSA:3.30.1330.10 319 513 5.1E-26 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SMART SM01211 1208 1471 1.8E-104 T 13-10-2018 Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Gene3D G3DSA:3.40.50.880 1163 1472 3.7E-79 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 Gene3D G3DSA:3.30.1330.10 762 927 1.2E-21 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SUPERFAMILY SSF56042 978 1125 3.14E-9 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SUPERFAMILY SSF56042 524 701 3.14E-37 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2398 07b5651093a7ccf381a67c5445be687e 1472 SUPERFAMILY SSF52317 1206 1471 4.42E-66 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 SUPERFAMILY SSF52540 8 228 2.98E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 Pfam PF00005 ABC transporter 25 174 1.6E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 Gene3D G3DSA:3.40.50.300 262 506 4.5E-42 T 13-10-2018 Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 Gene3D G3DSA:3.40.50.300 1 242 3.1E-56 T 13-10-2018 Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 SMART SM00382 34 222 1.8E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 SMART SM00382 283 477 3.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 SUPERFAMILY SSF52540 270 485 4.26E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0127 e00251ec127a7621a0c62959bdbb5b75 509 Pfam PF00005 ABC transporter 275 428 2.2E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2480 9aa9cfd450d502e8138306642af257a4 757 SUPERFAMILY SSF55073 602 728 1.73E-6 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2715 e4e92d77da9ad1e711f680f0be5f7d14 114 Gene3D G3DSA:2.60.120.10 1 114 3.9E-28 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2715 e4e92d77da9ad1e711f680f0be5f7d14 114 Pfam PF07883 Cupin domain 43 110 4.0E-18 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_2715 e4e92d77da9ad1e711f680f0be5f7d14 114 SUPERFAMILY SSF51182 18 112 9.17E-21 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 Pfam PF03176 MMPL family 733 939 2.5E-17 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 Pfam PF03176 MMPL family 286 464 2.9E-29 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 SUPERFAMILY SSF82866 726 942 6.8E-29 T 13-10-2018 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 Gene3D G3DSA:1.20.1640.10 766 950 5.2E-12 T 13-10-2018 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 SUPERFAMILY SSF82866 315 468 2.88E-37 T 13-10-2018 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 PRINTS PR00702 Acriflavin resistance protein family signature 335 356 1.1E-5 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 1.1E-5 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.1E-5 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0077 4af9f28efd89c367aa7e6a4110b57495 957 Gene3D G3DSA:1.20.1640.10 294 473 2.0E-16 T 13-10-2018 Spica_0570 9d661a0c0fc85d1d13c566e6dff81b03 249 ProSitePatterns PS01284 Thermonuclease family signature 2. 191 201 - T 13-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 Spica_0570 9d661a0c0fc85d1d13c566e6dff81b03 249 SMART SM00318 111 249 3.1E-30 T 13-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Spica_0570 9d661a0c0fc85d1d13c566e6dff81b03 249 Pfam PF00565 Staphylococcal nuclease homologue 143 247 1.4E-23 T 13-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 Spica_0570 9d661a0c0fc85d1d13c566e6dff81b03 249 Gene3D G3DSA:2.40.50.90 105 249 2.7E-40 T 13-10-2018 IPR035437 SNase-like, OB-fold superfamily Spica_0570 9d661a0c0fc85d1d13c566e6dff81b03 249 SUPERFAMILY SSF50199 109 248 2.62E-35 T 13-10-2018 Spica_2627 0c9027597f44641c90cde53c3d9f5efb 192 Gene3D G3DSA:1.10.340.30 5 189 1.9E-75 T 13-10-2018 Spica_2627 0c9027597f44641c90cde53c3d9f5efb 192 Pfam PF03352 Methyladenine glycosylase 10 186 1.7E-72 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 Spica_2627 0c9027597f44641c90cde53c3d9f5efb 192 SUPERFAMILY SSF48150 6 189 1.96E-73 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Spica_0037 1853377b8a3064f4414087f079606114 396 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 383 9.3E-34 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1307 dd52d5e93a2bbd0e6841b70f65a24d66 239 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1307 dd52d5e93a2bbd0e6841b70f65a24d66 239 SMART SM00382 29 201 3.0E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1307 dd52d5e93a2bbd0e6841b70f65a24d66 239 SUPERFAMILY SSF52540 3 214 5.67E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1307 dd52d5e93a2bbd0e6841b70f65a24d66 239 Gene3D G3DSA:3.40.50.300 1 219 5.7E-54 T 13-10-2018 Spica_1307 dd52d5e93a2bbd0e6841b70f65a24d66 239 Pfam PF00005 ABC transporter 21 150 6.1E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.685 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 SUPERFAMILY SSF54570 2 84 2.49E-32 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.6E-22 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.6E-22 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.6E-22 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 PIRSF PIRSF002144 1 93 1.6E-30 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 1.3E-44 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 Pfam PF00203 Ribosomal protein S19 3 83 1.7E-32 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 Gene3D G3DSA:3.30.860.10 1 93 3.3E-35 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0389 717527477ed4e69ee0bd7a606629f852 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 SUPERFAMILY SSF53850 30 521 1.69E-137 T 13-10-2018 Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 Gene3D G3DSA:3.40.190.10 35 502 3.8E-176 T 13-10-2018 Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 449 1.4E-95 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 Gene3D G3DSA:3.90.76.10 64 188 3.8E-176 T 13-10-2018 Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 Gene3D G3DSA:3.10.105.10 288 498 3.8E-176 T 13-10-2018 Spica_2539 4a887a1395cff3d4ad621b673ce5c3ce 528 PIRSF PIRSF002741 1 527 2.9E-119 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 SUPERFAMILY SSF57802 1 52 8.41E-24 T 13-10-2018 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 PIRSF PIRSF000071 1 53 5.6E-29 T 13-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 Pfam PF00301 Rubredoxin 3 49 4.1E-25 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 Gene3D G3DSA:2.20.28.10 1 53 2.1E-28 T 13-10-2018 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 PRINTS PR00163 Rubredoxin signature 3 19 1.5E-13 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 Spica_1835 a392f11b7fb7a79739f84d0724adff8e 53 PRINTS PR00163 Rubredoxin signature 33 49 1.5E-13 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 Gene3D G3DSA:3.40.50.10950 9 328 2.9E-129 T 13-10-2018 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 327 2.6E-118 T 13-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 Gene3D G3DSA:3.40.50.10750 143 304 2.9E-129 T 13-10-2018 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 SUPERFAMILY SSF53659 1 329 2.59E-88 T 13-10-2018 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 Pfam PF01515 Phosphate acetyl/butaryl transferase 3 327 6.3E-119 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_1147 8714c459fc5ad0d07e9c0d301a6d9b1d 332 PIRSF PIRSF000428 1 332 3.9E-108 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 2.3E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 SUPERFAMILY SSF52172 4 188 2.99E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 SMART SM00421 158 215 1.2E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 Pfam PF00072 Response regulator receiver domain 8 121 9.9E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 8.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 8.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 8.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 SMART SM00448 6 120 7.4E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 Gene3D G3DSA:3.40.50.12740 6 217 1.1E-60 T 13-10-2018 Spica_2284 1144ed4d62fa4926c9c4488c476704cc 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 Pfam PF13432 Tetratricopeptide repeat 116 173 8.8E-7 T 13-10-2018 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 Pfam PF13414 TPR repeat 50 89 2.2E-8 T 13-10-2018 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 SUPERFAMILY SSF48452 12 171 1.56E-32 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 SMART SM00028 109 142 16.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 SMART SM00028 75 108 5.1E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 SMART SM00028 41 74 0.064 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0998 b3cf0d2b722117fe4ca77f12bdf51f7f 194 Gene3D G3DSA:1.25.40.10 11 175 8.4E-36 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 224 250 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 Pfam PF04545 Sigma-70, region 4 203 252 6.0E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 254 3.5E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 Pfam PF04542 Sigma-70 region 2 30 102 1.7E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PRINTS PR00046 Major sigma-70 factor signature 57 70 2.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PRINTS PR00046 Major sigma-70 factor signature 207 219 2.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PRINTS PR00046 Major sigma-70 factor signature 81 89 2.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PRINTS PR00046 Major sigma-70 factor signature 224 239 2.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PRINTS PR00046 Major sigma-70 factor signature 239 250 2.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 PIRSF PIRSF000770 6 260 1.1E-60 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 Gene3D G3DSA:1.10.1740.10 16 100 6.2E-32 T 13-10-2018 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 SUPERFAMILY SSF88659 167 256 1.87E-23 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1521 fb79e9fe4618612b865c65b53253337a 262 SUPERFAMILY SSF88946 9 102 7.06E-28 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 SUPERFAMILY SSF88659 103 175 3.23E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1521 fb79e9fe4618612b865c65b53253337a 262 Gene3D G3DSA:1.20.140.160 101 257 5.6E-50 T 13-10-2018 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 Pfam PF04539 Sigma-70 region 3 110 188 2.6E-8 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Spica_1521 fb79e9fe4618612b865c65b53253337a 262 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 30 255 2.7E-88 T 13-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SUPERFAMILY SSF55781 359 529 3.71E-17 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00091 129 194 11.0 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00091 254 322 0.15 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00091 1 63 3.6 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00086 69 111 26.0 T 13-10-2018 IPR001610 PAC motif Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00086 326 363 73.0 T 13-10-2018 IPR001610 PAC motif Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00086 200 242 0.21 T 13-10-2018 IPR001610 PAC motif Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Pfam PF13426 PAS domain 140 240 1.4E-12 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SUPERFAMILY SSF55785 240 361 9.77E-15 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 TIGRFAM TIGR00277 HDIG: HDIG domain 565 656 1.4E-7 T 13-10-2018 IPR006675 HDIG domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Gene3D G3DSA:3.30.450.20 251 368 1.3E-17 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Gene3D G3DSA:3.30.450.40 369 532 3.5E-17 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Gene3D G3DSA:3.30.450.20 126 250 7.7E-15 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SUPERFAMILY SSF109604 549 727 1.38E-37 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Pfam PF13487 HD domain 616 678 7.1E-19 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00065 385 537 2.1E-6 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Gene3D G3DSA:3.30.450.20 1 122 7.2E-13 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SMART SM00471 561 696 1.1E-10 T 13-10-2018 IPR003607 HD/PDEase domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 134 249 2.9E-10 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 250 368 4.2E-7 T 13-10-2018 IPR000014 PAS domain Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Gene3D G3DSA:1.10.3210.10 539 733 1.1E-64 T 13-10-2018 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SUPERFAMILY SSF55785 140 251 1.05E-14 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Pfam PF13185 GAF domain 384 528 1.7E-12 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 SUPERFAMILY SSF55785 2 110 5.23E-15 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Pfam PF08448 PAS fold 260 365 8.7E-10 T 13-10-2018 IPR013656 PAS fold-4 Spica_2139 ab43948ac13b032440e89ef3881fbff6 747 Pfam PF08448 PAS fold 6 111 1.1E-7 T 13-10-2018 IPR013656 PAS fold-4 Spica_1897 52e5ba8f4d4b11ba3c9c1c9bd707f635 281 SUPERFAMILY SSF161098 4 278 1.12E-55 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1897 52e5ba8f4d4b11ba3c9c1c9bd707f635 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 276 4.3E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1897 52e5ba8f4d4b11ba3c9c1c9bd707f635 281 Gene3D G3DSA:1.10.3720.10 3 274 2.8E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2338 e297692e64d4f38b616295c164b0f709 363 Gene3D G3DSA:3.40.50.180 170 362 5.2E-75 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_2338 e297692e64d4f38b616295c164b0f709 363 SUPERFAMILY SSF52738 175 362 3.27E-68 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_2338 e297692e64d4f38b616295c164b0f709 363 SUPERFAMILY SSF52172 1 135 3.98E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2338 e297692e64d4f38b616295c164b0f709 363 Gene3D G3DSA:3.40.50.2300 1 136 6.7E-29 T 13-10-2018 Spica_2338 e297692e64d4f38b616295c164b0f709 363 SMART SM00448 2 116 1.9E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2338 e297692e64d4f38b616295c164b0f709 363 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 363 38.494 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2338 e297692e64d4f38b616295c164b0f709 363 PIRSF PIRSF000876 1 363 7.4E-130 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2338 e297692e64d4f38b616295c164b0f709 363 Pfam PF01339 CheB methylesterase 180 358 6.3E-62 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2338 e297692e64d4f38b616295c164b0f709 363 Pfam PF00072 Response regulator receiver domain 4 108 1.1E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 Gene3D G3DSA:3.40.50.1000 69 288 4.6E-23 T 13-10-2018 IPR023214 HAD superfamily Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 SUPERFAMILY SSF56784 67 313 3.48E-28 T 13-10-2018 IPR036412 HAD-like superfamily Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 Pfam PF13419 Haloacid dehalogenase-like hydrolase 138 275 1.3E-9 T 13-10-2018 Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 70 81 1.7E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 181 194 1.7E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_1950 5c975c32359235297d0220c3c4fb2dd1 319 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 266 279 1.7E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 SUPERFAMILY SSF51011 643 720 2.73E-18 T 13-10-2018 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Gene3D G3DSA:2.60.40.1180 721 830 1.6E-16 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Gene3D G3DSA:2.60.40.1180 673 720 1.1E-13 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 SUPERFAMILY SSF51445 304 640 4.81E-91 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 SUPERFAMILY SSF117125 723 826 5.36E-18 T 13-10-2018 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 SUPERFAMILY SSF74650 1 303 1.76E-48 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Gene3D G3DSA:3.20.20.80 302 672 2.2E-150 T 13-10-2018 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Pfam PF01055 Glycosyl hydrolases family 31 296 725 2.6E-122 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Gene3D G3DSA:2.60.40.1760 140 301 1.4E-43 T 13-10-2018 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Gene3D G3DSA:2.60.40.1760 1 113 3.1E-20 T 13-10-2018 Spica_0739 cfecc1989e3ef3a5edb588d491aacfe9 833 Pfam PF13802 Galactose mutarotase-like 215 274 5.2E-16 T 13-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain Spica_0724 0142d21b65c7193522dd471d7e9250ec 385 Pfam PF07907 YibE/F-like protein 136 373 4.3E-73 T 13-10-2018 IPR012507 YibE/F-like Spica_2030 10f3a68fd6c3be24a4910624d6e71d02 865 SUPERFAMILY SSF53850 35 388 9.95E-29 T 13-10-2018 Spica_2030 10f3a68fd6c3be24a4910624d6e71d02 865 Gene3D G3DSA:3.40.190.10 35 369 9.9E-22 T 13-10-2018 Spica_2030 10f3a68fd6c3be24a4910624d6e71d02 865 Gene3D G3DSA:3.10.105.10 92 360 9.9E-22 T 13-10-2018 Spica_2030 10f3a68fd6c3be24a4910624d6e71d02 865 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 36 285 2.5E-17 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain Spica_0598 eefcd33c800229f99f3859b1ae945976 313 SUPERFAMILY SSF161098 69 298 4.32E-50 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0598 eefcd33c800229f99f3859b1ae945976 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 307 9.8E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0598 eefcd33c800229f99f3859b1ae945976 313 Gene3D G3DSA:1.10.3720.10 67 313 1.3E-61 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Gene3D G3DSA:1.10.150.870 729 822 3.5E-6 T 13-10-2018 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 SUPERFAMILY SSF89550 9 79 5.49E-8 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 269 675 2.6E-107 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Gene3D G3DSA:3.20.20.140 154 246 1.7E-5 T 13-10-2018 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Gene3D G3DSA:3.20.20.140 3 110 1.8E-22 T 13-10-2018 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Pfam PF02811 PHP domain 8 92 5.0E-13 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 Pfam PF14579 Helix-hairpin-helix motif 748 832 1.8E-18 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 SMART SM00481 1 70 2.1E-11 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_1412 c8174f613785228a0c52c7e4735d04eb 1011 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 158 950 1.3E-154 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 1.1E-103 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 Gene3D G3DSA:3.30.70.980 86 236 1.7E-53 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 Pfam PF01709 Transcriptional regulator 5 237 3.8E-97 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 Gene3D G3DSA:1.10.10.200 1 81 2.8E-37 T 13-10-2018 IPR017856 Integrase-like, N-terminal Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 SUPERFAMILY SSF75625 3 245 1.31E-95 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 37.044 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1339 054245786b2abf8db97d8cd7b6c95490 246 Gene3D G3DSA:3.30.70.980 130 205 1.7E-53 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Spica_1515 491dbe805a77d75d86b61262950c7195 514 Gene3D G3DSA:3.30.70.1230 263 463 4.8E-57 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1515 491dbe805a77d75d86b61262950c7195 514 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 270 447 1.4E-34 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1515 491dbe805a77d75d86b61262950c7195 514 SUPERFAMILY SSF55073 266 451 1.4E-55 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1515 491dbe805a77d75d86b61262950c7195 514 SMART SM00044 234 432 2.9E-13 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1026 512caf1694927a5dede3aa2046018f19 281 Pfam PF01551 Peptidase family M23 183 275 4.5E-17 T 13-10-2018 IPR016047 Peptidase M23 Spica_1026 512caf1694927a5dede3aa2046018f19 281 Gene3D G3DSA:2.70.70.10 150 278 7.6E-19 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1026 512caf1694927a5dede3aa2046018f19 281 SUPERFAMILY SSF51261 44 276 5.13E-22 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1026 512caf1694927a5dede3aa2046018f19 281 SMART SM00257 95 139 1.2E-9 T 13-10-2018 IPR018392 LysM domain Spica_1026 512caf1694927a5dede3aa2046018f19 281 SMART SM00257 44 88 2.3E-17 T 13-10-2018 IPR018392 LysM domain Spica_1026 512caf1694927a5dede3aa2046018f19 281 Pfam PF01476 LysM domain 96 139 4.5E-10 T 13-10-2018 IPR018392 LysM domain Spica_1026 512caf1694927a5dede3aa2046018f19 281 Pfam PF01476 LysM domain 45 88 1.2E-16 T 13-10-2018 IPR018392 LysM domain Spica_1026 512caf1694927a5dede3aa2046018f19 281 Gene3D G3DSA:3.10.350.10 93 149 1.3E-13 T 13-10-2018 IPR036779 LysM domain superfamily Spica_1026 512caf1694927a5dede3aa2046018f19 281 Gene3D G3DSA:3.10.350.10 40 92 4.6E-19 T 13-10-2018 IPR036779 LysM domain superfamily Spica_2367 b9c6c4922dc8620b203313300f905064 445 Gene3D G3DSA:3.30.420.40 197 409 2.6E-76 T 13-10-2018 Spica_2367 b9c6c4922dc8620b203313300f905064 445 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 SUPERFAMILY SSF53067 1 197 2.78E-65 T 13-10-2018 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PIRSF PIRSF000722 1 402 3.9E-145 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 Gene3D G3DSA:3.30.420.40 1 196 3.0E-70 T 13-10-2018 Spica_2367 b9c6c4922dc8620b203313300f905064 445 SUPERFAMILY SSF53067 159 399 5.06E-85 T 13-10-2018 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 3 14 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 174 187 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 301 314 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 323 339 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 380 392 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 PRINTS PR00471 Acetate kinase family signature 204 225 1.9E-38 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 TIGRFAM TIGR00016 ackA: acetate kinase 1 399 8.6E-154 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 Pfam PF00871 Acetokinase family 3 391 3.1E-148 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 Hamap MF_00020 Acetate kinase [ackA]. 1 402 177.125 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2367 b9c6c4922dc8620b203313300f905064 445 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2718 4d6243d67a4e7aea9e10ab426176b36f 344 PIRSF PIRSF017617 1 344 2.4E-131 T 13-10-2018 IPR023603 Threonine aldolase Spica_2718 4d6243d67a4e7aea9e10ab426176b36f 344 Gene3D G3DSA:3.40.640.10 1 244 1.3E-94 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_2718 4d6243d67a4e7aea9e10ab426176b36f 344 SUPERFAMILY SSF53383 1 339 2.13E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2718 4d6243d67a4e7aea9e10ab426176b36f 344 Gene3D G3DSA:3.90.1150.10 246 342 4.7E-23 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2718 4d6243d67a4e7aea9e10ab426176b36f 344 Pfam PF01212 Beta-eliminating lyase 3 283 4.8E-95 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 PIRSF PIRSF002849 1 314 6.3E-123 T 13-10-2018 Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 Gene3D G3DSA:1.10.8.300 202 309 1.4E-31 T 13-10-2018 Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 Gene3D G3DSA:3.40.50.300 20 185 2.2E-43 T 13-10-2018 Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 SUPERFAMILY SSF52540 6 284 3.31E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 2.3E-59 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spica_2309 84aa726bb741aab2a19c644aa0aae9c6 318 SMART SM00382 36 177 0.0013 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 Gene3D G3DSA:3.30.499.10 270 436 3.2E-50 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 SUPERFAMILY SSF52016 447 646 7.06E-51 T 13-10-2018 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 Gene3D G3DSA:3.30.499.20 4 267 1.5E-82 T 13-10-2018 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 Pfam PF00694 Aconitase C-terminal domain 523 579 1.4E-22 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 SUPERFAMILY SSF53732 1 421 4.32E-147 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 PRINTS PR00415 Aconitase family signature 124 139 2.2E-25 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 PRINTS PR00415 Aconitase family signature 110 123 2.2E-25 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 PRINTS PR00415 Aconitase family signature 349 362 2.2E-25 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 PRINTS PR00415 Aconitase family signature 186 199 2.2E-25 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 PRINTS PR00415 Aconitase family signature 200 213 2.2E-25 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 4 645 4.5E-272 T 13-10-2018 IPR006250 Aconitase, putative Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 Gene3D G3DSA:3.20.19.10 470 648 3.7E-43 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 8.9E-109 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_1089 27d47767ffd3d897bdab2f3e2f6750fa 649 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 9 407 1.0E-158 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 14 401 2.9E-56 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 276 295 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 PIRSF PIRSF000108 1 408 2.2E-189 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 SMART SM01329 16 401 2.1E-97 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 Gene3D G3DSA:3.40.718.10 9 408 4.7E-181 T 13-10-2018 Spica_1599 5423cb80f5f800786929e9b54d8f9ef5 408 SUPERFAMILY SSF53659 9 406 2.69E-128 T 13-10-2018 Spica_2641 84c59954efd8d1cccfa3d86180d6ac01 314 SUPERFAMILY SSF56281 7 274 1.23E-18 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2641 84c59954efd8d1cccfa3d86180d6ac01 314 Pfam PF13483 Beta-lactamase superfamily domain 8 168 3.6E-13 T 13-10-2018 Spica_0474 f3266bd7b8a778be671e7aadcb9868a3 236 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 1 236 41.438 T 13-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0474 f3266bd7b8a778be671e7aadcb9868a3 236 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 236 4.8E-74 T 13-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0474 f3266bd7b8a778be671e7aadcb9868a3 236 Pfam PF01048 Phosphorylase superfamily 2 233 3.5E-44 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spica_0474 f3266bd7b8a778be671e7aadcb9868a3 236 SUPERFAMILY SSF53167 2 234 1.7E-63 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Spica_0474 f3266bd7b8a778be671e7aadcb9868a3 236 Gene3D G3DSA:3.40.50.1580 1 236 1.5E-64 T 13-10-2018 Spica_1173 ca20b199c744021adc44c5e83bb2cc0b 224 SUPERFAMILY SSF56300 1 212 8.32E-27 T 13-10-2018 Spica_1173 ca20b199c744021adc44c5e83bb2cc0b 224 Gene3D G3DSA:3.60.21.10 36 212 1.6E-11 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_1173 ca20b199c744021adc44c5e83bb2cc0b 224 Pfam PF00149 Calcineurin-like phosphoesterase 1 194 9.0E-7 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 SUPERFAMILY SSF54843 3 115 9.03E-36 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 115 24.57 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 10 112 5.3E-28 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 Gene3D G3DSA:3.90.470.10 3 120 2.1E-41 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0390 0df1e2e8b98bc26a3b1d1a73f5edd58a 120 Pfam PF00237 Ribosomal protein L22p/L17e 10 112 5.6E-30 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Spica_1808 37299536168d7b3dcad524f001b9bd58 129 Pfam PF06291 Bor protein 82 120 1.3E-6 T 13-10-2018 IPR010438 Bor GO:0009279 Spica_1196 b5221a487911f7b94fc7be1218880827 330 SMART SM00244 33 214 5.6E-32 T 13-10-2018 IPR001107 Band 7 domain Spica_1196 b5221a487911f7b94fc7be1218880827 330 Pfam PF01145 SPFH domain / Band 7 family 37 226 2.5E-23 T 13-10-2018 IPR001107 Band 7 domain Spica_1196 b5221a487911f7b94fc7be1218880827 330 Gene3D G3DSA:3.30.479.30 98 205 1.8E-14 T 13-10-2018 Spica_1196 b5221a487911f7b94fc7be1218880827 330 TIGRFAM TIGR01933 hflK: HflK protein 35 316 4.4E-92 T 13-10-2018 IPR010201 HflK GO:0016021 Spica_1196 b5221a487911f7b94fc7be1218880827 330 SUPERFAMILY SSF117892 106 216 3.66E-16 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Spica_2735 341670698aa8e8c54e2c6555312f613e 713 Pfam PF16927 N-terminal 7TM region of histidine kinase 10 225 1.8E-7 T 13-10-2018 IPR031621 Histidine kinase, N-terminal 7TM region Spica_2735 341670698aa8e8c54e2c6555312f613e 713 SMART SM00331 494 712 5.9E-44 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2735 341670698aa8e8c54e2c6555312f613e 713 SUPERFAMILY SSF81606 505 712 1.7E-5 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2735 341670698aa8e8c54e2c6555312f613e 713 Gene3D G3DSA:3.60.40.10 491 713 1.9E-45 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2735 341670698aa8e8c54e2c6555312f613e 713 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 521 712 4.1E-37 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 546 680 4.3E-9 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Pfam PF00874 PRD domain 322 408 1.5E-16 T 13-10-2018 IPR011608 PRD domain GO:0006355 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Pfam PF08279 HTH domain 6 63 1.8E-8 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Pfam PF08279 HTH domain 93 149 3.0E-5 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 SUPERFAMILY SSF55804 553 673 1.31E-9 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Gene3D G3DSA:3.40.930.10 542 682 5.7E-8 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 SUPERFAMILY SSF52794 419 493 3.77E-10 T 13-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 SUPERFAMILY SSF63520 311 411 7.59E-17 T 13-10-2018 IPR036634 PRD domain superfamily GO:0006355 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Gene3D G3DSA:1.10.10.10 77 154 1.9E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Gene3D G3DSA:1.10.10.10 1 68 2.0E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Gene3D G3DSA:3.40.50.2300 419 502 8.6E-8 T 13-10-2018 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 Gene3D G3DSA:1.10.1790.10 314 410 1.5E-15 T 13-10-2018 Spica_2252 d5f7f092783ca144f7d8042f4b6f2086 685 SUPERFAMILY SSF46785 90 150 5.95E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2223 83d1a90057b33b43284047fe371cd627 297 SUPERFAMILY SSF161098 59 284 5.36E-59 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2223 83d1a90057b33b43284047fe371cd627 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 284 7.8E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2223 83d1a90057b33b43284047fe371cd627 297 Gene3D G3DSA:1.10.3720.10 55 296 3.2E-70 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1121 1d4bd554f8bbd2349b3a0ea25626b162 143 SUPERFAMILY SSF52540 22 127 5.28E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1121 1d4bd554f8bbd2349b3a0ea25626b162 143 Gene3D G3DSA:3.40.50.300 1 141 3.5E-40 T 13-10-2018 Spica_1121 1d4bd554f8bbd2349b3a0ea25626b162 143 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6 123 3.5E-35 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Spica_1121 1d4bd554f8bbd2349b3a0ea25626b162 143 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 136 8.4E-36 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Spica_1900 da1add4f5260fd961099bd48e685578f 213 SUPERFAMILY SSF161098 7 192 1.09E-44 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1900 da1add4f5260fd961099bd48e685578f 213 Gene3D G3DSA:1.10.3720.10 1 209 5.1E-52 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1900 da1add4f5260fd961099bd48e685578f 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 207 6.4E-25 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1900 da1add4f5260fd961099bd48e685578f 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 6 103 2.3E-22 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 Gene3D G3DSA:1.10.1060.10 355 433 1.6E-9 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 25 429 3.5E-74 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 129 275 1.5E-11 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 Pfam PF13375 RnfC Barrel sandwich hybrid domain 25 102 3.2E-13 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 SUPERFAMILY SSF142984 287 355 1.24E-7 T 13-10-2018 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 SUPERFAMILY SSF46548 362 426 4.88E-13 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 Pfam PF10531 SLBB domain 288 324 6.4E-8 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 Pfam PF13237 4Fe-4S dicluster domain 365 417 1.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 SUPERFAMILY SSF142019 164 294 2.75E-10 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_1277 18fd344ff7a35a0868d44c7de8927481 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 406 417 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 Gene3D G3DSA:3.30.420.40 198 397 2.4E-67 T 13-10-2018 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 323 339 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 301 314 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 377 389 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 204 225 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 5 16 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PRINTS PR00471 Acetate kinase family signature 174 187 1.5E-39 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 TIGRFAM TIGR00016 ackA: acetate kinase 3 395 1.0E-111 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 SUPERFAMILY SSF53067 4 196 2.52E-54 T 13-10-2018 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 SUPERFAMILY SSF53067 159 396 2.59E-75 T 13-10-2018 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 Pfam PF00871 Acetokinase family 5 389 9.0E-113 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 Gene3D G3DSA:3.30.420.40 1 196 9.4E-59 T 13-10-2018 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 PIRSF PIRSF000722 1 399 4.5E-121 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_0710 83214f7724e26ba6f1e0bd287124b8ae 399 Hamap MF_00020 Acetate kinase [ackA]. 1 399 151.558 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 216 31.436 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 215 1.4E-56 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 Gene3D G3DSA:3.40.50.880 1 219 2.3E-66 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 SUPERFAMILY SSF52317 2 215 2.78E-45 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 PIRSF PIRSF000495 1 219 3.8E-57 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Spica_2434 dd20bbc27c1bdeca058e7d0f80241375 220 Pfam PF00117 Glutamine amidotransferase class-I 7 203 2.3E-19 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_1502 93849d4b8a9e10de2f91b8e5ac63cd66 432 SUPERFAMILY SSF52540 75 334 3.45E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1502 93849d4b8a9e10de2f91b8e5ac63cd66 432 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 2 432 46.371 T 13-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1502 93849d4b8a9e10de2f91b8e5ac63cd66 432 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 127 319 3.0E-45 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1502 93849d4b8a9e10de2f91b8e5ac63cd66 432 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 71 1.0E-8 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1502 93849d4b8a9e10de2f91b8e5ac63cd66 432 Gene3D G3DSA:3.40.50.12240 13 432 2.4E-109 T 13-10-2018 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 Gene3D G3DSA:3.30.420.40 255 490 9.1E-45 T 13-10-2018 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 Gene3D G3DSA:3.30.420.40 1 245 6.8E-70 T 13-10-2018 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 288 444 2.5E-18 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 SUPERFAMILY SSF53067 257 487 2.62E-33 T 13-10-2018 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 SUPERFAMILY SSF53067 2 248 3.42E-63 T 13-10-2018 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 245 9.8E-59 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_0049 11192f9b696b95c3230f355b60f7a0f3 491 PIRSF PIRSF000538 1 490 1.9E-106 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_2036 39081f78bd8613adcee4edcfde830caf 328 Gene3D G3DSA:3.40.366.10 8 296 3.2E-86 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 Spica_2036 39081f78bd8613adcee4edcfde830caf 328 PIRSF PIRSF000446 4 322 1.2E-73 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Spica_2036 39081f78bd8613adcee4edcfde830caf 328 Gene3D G3DSA:3.30.70.250 126 208 3.2E-86 T 13-10-2018 Spica_2036 39081f78bd8613adcee4edcfde830caf 328 SUPERFAMILY SSF52151 7 321 3.14E-63 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Spica_2036 39081f78bd8613adcee4edcfde830caf 328 Pfam PF00698 Acyl transferase domain 9 293 3.8E-34 T 13-10-2018 IPR014043 Acyl transferase Spica_2036 39081f78bd8613adcee4edcfde830caf 328 SUPERFAMILY SSF55048 140 207 3.92E-15 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding Spica_2036 39081f78bd8613adcee4edcfde830caf 328 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 10 325 1.1E-30 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 SUPERFAMILY SSF46785 26 117 5.52E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 9.1E-18 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 9.1E-18 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 9.1E-18 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 9.1E-18 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 Pfam PF01022 Bacterial regulatory protein, arsR family 43 88 1.2E-17 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 60 78 - T 13-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 SMART SM00418 36 115 1.1E-28 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2263 b88651a8a8e9fa36d2f64af5795038a3 123 Gene3D G3DSA:1.10.10.10 2 122 1.6E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 SUPERFAMILY SSF55874 221 374 1.57E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 376 5.5E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 1.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 185 199 1.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 1.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 1.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 SMART SM00387 271 377 4.6E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1938 85bb80fa20888674fa7344eb4325f99d 385 Gene3D G3DSA:3.30.565.10 222 375 7.3E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0014 a46018071075aecf967aaba30755c9e4 381 Gene3D G3DSA:1.20.1090.10 185 381 4.0E-29 T 13-10-2018 Spica_0014 a46018071075aecf967aaba30755c9e4 381 SUPERFAMILY SSF56796 8 380 1.57E-50 T 13-10-2018 Spica_0014 a46018071075aecf967aaba30755c9e4 381 Gene3D G3DSA:3.40.50.1970 2 180 3.1E-21 T 13-10-2018 Spica_0014 a46018071075aecf967aaba30755c9e4 381 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 372 9.6E-48 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Spica_1727 932962fd4f649beb73ca8befd1c763db 254 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 165 1.2E-14 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Spica_1727 932962fd4f649beb73ca8befd1c763db 254 Gene3D G3DSA:3.30.930.10 4 254 1.1E-70 T 13-10-2018 Spica_1727 932962fd4f649beb73ca8befd1c763db 254 SUPERFAMILY SSF55681 4 253 4.05E-73 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 SUPERFAMILY SSF52009 374 481 4.84E-12 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 273 325 1.0E-4 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:3.20.20.60 520 875 1.2E-132 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 764 782 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 SUPERFAMILY SSF51621 520 874 6.63E-105 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 520 872 8.4E-76 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 SUPERFAMILY SSF56059 2 358 1.41E-37 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 435 446 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:3.50.30.10 362 492 5.7E-31 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:1.10.189.10 324 504 5.7E-31 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Pfam PF00391 PEP-utilising enzyme, mobile domain 408 481 1.0E-8 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:3.30.470.20 229 318 1.2E-13 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 PIRSF PIRSF000853 1 877 4.5E-254 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:1.20.80.30 107 191 3.5E-10 T 13-10-2018 Spica_1144 13ea51225f8d5dde0eff8379b742ef7f 877 Gene3D G3DSA:3.30.1490.20 19 200 3.5E-10 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_1981 2043eca9d00a951210cda41395026624 251 SMART SM00420 8 60 4.4E-11 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_1981 2043eca9d00a951210cda41395026624 251 SUPERFAMILY SSF100950 72 232 2.44E-34 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_1981 2043eca9d00a951210cda41395026624 251 SMART SM01134 71 232 1.4E-67 T 13-10-2018 Spica_1981 2043eca9d00a951210cda41395026624 251 Pfam PF00455 DeoR C terminal sensor domain 73 231 6.6E-51 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain Spica_1981 2043eca9d00a951210cda41395026624 251 SUPERFAMILY SSF46785 5 62 5.71E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1981 2043eca9d00a951210cda41395026624 251 Gene3D G3DSA:1.10.10.10 5 53 3.1E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1981 2043eca9d00a951210cda41395026624 251 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 4.3E-13 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_1981 2043eca9d00a951210cda41395026624 251 Gene3D G3DSA:3.30.750.70 68 130 3.4E-5 T 13-10-2018 Spica_1481 864b05a4035491f8f44e4826e215dff7 231 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 17 229 28.906 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Spica_1481 864b05a4035491f8f44e4826e215dff7 231 Pfam PF02390 Putative methyltransferase 57 222 2.0E-52 T 13-10-2018 Spica_1481 864b05a4035491f8f44e4826e215dff7 231 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 43 228 9.1E-47 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Spica_1481 864b05a4035491f8f44e4826e215dff7 231 SUPERFAMILY SSF53335 11 225 1.86E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1481 864b05a4035491f8f44e4826e215dff7 231 Gene3D G3DSA:3.40.50.150 23 230 6.8E-63 T 13-10-2018 Spica_2776 9dd884cee532db5bd0d198bb9c4d11a1 182 SUPERFAMILY SSF55874 8 111 6.81E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2776 9dd884cee532db5bd0d198bb9c4d11a1 182 Gene3D G3DSA:3.30.565.10 4 111 2.0E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2776 9dd884cee532db5bd0d198bb9c4d11a1 182 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 8 107 2.2E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 PRINTS PR00207 Flagellin signature 74 93 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 PRINTS PR00207 Flagellin signature 109 132 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 PRINTS PR00207 Flagellin signature 35 52 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 Pfam PF00700 Bacterial flagellin C-terminal helical region 201 285 4.5E-25 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 Gene3D G3DSA:1.20.58.1830 3 31 2.7E-60 T 13-10-2018 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 Gene3D G3DSA:1.20.1330.10 43 182 2.7E-60 T 13-10-2018 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 6.2E-41 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 Gene3D G3DSA:1.10.8.410 233 286 4.2E-24 T 13-10-2018 Spica_1128 ec09ad80f649d16e3e55ed339144487f 286 SUPERFAMILY SSF64518 1 286 2.48E-82 T 13-10-2018 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 6.5E-84 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 Gene3D G3DSA:3.30.420.40 5 252 7.8E-107 T 13-10-2018 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 Gene3D G3DSA:3.30.420.40 253 498 8.5E-87 T 13-10-2018 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 SUPERFAMILY SSF53067 254 489 3.7E-83 T 13-10-2018 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 SUPERFAMILY SSF53067 7 254 1.04E-93 T 13-10-2018 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 PIRSF PIRSF000538 5 498 2.2E-180 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 Hamap MF_00186 Glycerol kinase [glpK]. 5 496 56.273 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 493 4.0E-216 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 448 1.6E-57 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spica_0199 e96a2dd6a761207d4af75e7c56b2fb0d 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 137 149 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Pfam PF00072 Response regulator receiver domain 13 122 4.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 181 194 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Gene3D G3DSA:3.40.50.300 129 327 6.9E-67 T 13-10-2018 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 SMART SM00448 11 122 1.8E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 SMART SM00382 177 329 2.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Gene3D G3DSA:3.40.50.2300 12 128 9.1E-37 T 13-10-2018 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 370 379 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 SUPERFAMILY SSF52172 11 202 1.21E-44 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Gene3D G3DSA:1.10.10.60 417 469 1.1E-13 T 13-10-2018 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Pfam PF00158 Sigma-54 interaction domain 158 323 2.1E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 SUPERFAMILY SSF46689 371 468 4.93E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Pfam PF02954 Bacterial regulatory protein, Fis family 425 466 1.8E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 SUPERFAMILY SSF52540 156 398 3.77E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 5.8E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 5.8E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1193 6b5639d8a797f9bec2f833adba86e04e 470 Gene3D G3DSA:1.10.8.60 328 394 1.2E-23 T 13-10-2018 Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 PRINTS PR01438 Universal stress protein signature 6 24 1.5E-6 T 13-10-2018 IPR006015 Universal stress protein A Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 PRINTS PR01438 Universal stress protein signature 128 150 1.5E-6 T 13-10-2018 IPR006015 Universal stress protein A Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 PRINTS PR01438 Universal stress protein signature 110 122 1.5E-6 T 13-10-2018 IPR006015 Universal stress protein A Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 SUPERFAMILY SSF52402 6 152 8.37E-27 T 13-10-2018 Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 Pfam PF00582 Universal stress protein family 7 150 3.6E-20 T 13-10-2018 IPR006016 UspA Spica_1813 43baeb68f9ee0ab66be6465db586a2a0 161 Gene3D G3DSA:3.40.50.620 5 151 3.0E-25 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 SUPERFAMILY SSF53335 73 263 5.34E-49 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 263 3.5E-67 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 108 128 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 29 42 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 7.9E-42 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 Gene3D G3DSA:3.40.50.150 72 270 7.2E-63 T 13-10-2018 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 PIRSF PIRSF000410 2 271 1.1E-78 T 13-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 SUPERFAMILY SSF47757 5 72 1.57E-14 T 13-10-2018 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 SMART SM00138 7 269 1.9E-105 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 Gene3D G3DSA:1.10.155.10 2 71 2.0E-14 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_2765 9fa8237b1599266ad7fb379bd30db35b 271 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 59 2.8E-13 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_0513 23b47c83d4af290e562b9f33934c1007 290 Gene3D G3DSA:3.30.360.10 110 282 4.9E-11 T 13-10-2018 Spica_0513 23b47c83d4af290e562b9f33934c1007 290 Gene3D G3DSA:3.40.50.720 6 109 8.8E-9 T 13-10-2018 Spica_0513 23b47c83d4af290e562b9f33934c1007 290 SUPERFAMILY SSF51735 13 108 3.06E-10 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0513 23b47c83d4af290e562b9f33934c1007 290 SUPERFAMILY SSF55347 95 251 2.88E-9 T 13-10-2018 Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 116 126 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 38 146 3.0E-35 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 Pfam PF02130 Uncharacterized protein family UPF0054 35 145 6.5E-32 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 3 150 20.052 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 Gene3D G3DSA:3.40.390.30 8 149 1.2E-37 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 Spica_1229 ffe6686f54d879e23d8f9fe43ee6a256 153 SUPERFAMILY SSF55486 12 146 2.93E-35 T 13-10-2018 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 SUPERFAMILY SSF53822 91 364 2.55E-42 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 Gene3D G3DSA:3.40.50.2300 192 365 1.1E-53 T 13-10-2018 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 SMART SM00345 12 71 6.4E-21 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 Pfam PF13377 Periplasmic binding protein-like domain 200 370 5.0E-20 T 13-10-2018 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 SUPERFAMILY SSF46785 6 75 1.65E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 Gene3D G3DSA:3.40.50.2300 92 362 1.1E-53 T 13-10-2018 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 6.1E-20 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 Gene3D G3DSA:1.10.10.10 6 75 2.5E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.6E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1910 f673d6a48cadbe24f0a5f9973d8cf864 374 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.6E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 Gene3D G3DSA:1.10.1040.10 196 355 8.7E-34 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PIRSF PIRSF000114 1 355 3.5E-84 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 57 84 9.6E-24 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 257 274 9.6E-24 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 140 160 9.6E-24 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 180 204 9.6E-24 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 7 24 9.6E-24 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 Gene3D G3DSA:3.40.50.720 1 194 5.1E-45 T 13-10-2018 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 SUPERFAMILY SSF51735 4 182 1.03E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 3 350 28.248 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 SUPERFAMILY SSF48179 187 352 2.55E-33 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 187 347 9.4E-39 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0491 7dfc8aad9b8bcdad192ec6eedcf0f4dc 356 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 166 5.3E-39 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 SUPERFAMILY SSF50998 396 689 2.43E-23 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 SMART SM00564 393 424 84.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 SMART SM00564 509 541 710.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 SMART SM00564 550 582 3.6E-4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 SMART SM00564 628 660 310.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 Gene3D G3DSA:2.130.10.10 541 692 5.3E-21 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 Gene3D G3DSA:2.130.10.10 366 538 1.5E-7 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 Pfam PF13360 PQQ-like domain 629 691 3.6E-4 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 Pfam PF13360 PQQ-like domain 548 616 1.3E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Spica_0685 dfe31f06a7f1bd6c56864699a27813a1 693 Pfam PF04773 FecR protein 96 207 5.5E-8 T 13-10-2018 IPR006860 FecR protein Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Pfam PF02954 Bacterial regulatory protein, Fis family 478 514 2.6E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Gene3D G3DSA:3.40.50.300 201 385 9.9E-70 T 13-10-2018 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 SMART SM00382 235 379 7.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 SUPERFAMILY SSF46689 427 517 3.88E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 SUPERFAMILY SSF55781 5 170 1.79E-18 T 13-10-2018 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Gene3D G3DSA:1.10.10.60 454 524 7.0E-13 T 13-10-2018 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 239 252 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 428 437 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 484 501 3.5E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 501 521 3.5E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Pfam PF00158 Sigma-54 interaction domain 215 382 5.9E-74 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 SUPERFAMILY SSF52540 214 458 2.57E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 301 316 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 SMART SM00065 29 183 1.3E-12 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Gene3D G3DSA:1.10.8.60 386 453 7.3E-26 T 13-10-2018 Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Gene3D G3DSA:3.30.450.40 9 184 3.1E-39 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_1649 e264a1997a21b34a5cf35355424f0a0f 530 Pfam PF01590 GAF domain 39 170 1.1E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1511 0c176f55b16905c7ede5095d2367ea6c 432 Pfam PF13177 DNA polymerase III, delta subunit 11 256 1.1E-29 T 13-10-2018 Spica_1511 0c176f55b16905c7ede5095d2367ea6c 432 SUPERFAMILY SSF52540 15 275 1.5E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0514 9a86fd196b66cb3d31cad93694bf9069 234 SUPERFAMILY SSF53448 4 232 6.31E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0514 9a86fd196b66cb3d31cad93694bf9069 234 Pfam PF02348 Cytidylyltransferase 8 96 1.1E-21 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 Spica_0514 9a86fd196b66cb3d31cad93694bf9069 234 Gene3D G3DSA:3.90.550.10 3 233 2.1E-67 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 Pfam PF00107 Zinc-binding dehydrogenase 174 300 1.3E-26 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 339 56.536 T 13-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 134 1.5E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 338 2.8E-147 T 13-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 Gene3D G3DSA:3.90.180.10 21 327 4.4E-111 T 13-10-2018 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 Gene3D G3DSA:3.40.50.720 153 285 4.4E-111 T 13-10-2018 Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 SUPERFAMILY SSF51735 141 304 1.53E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0890 d2b8e1ab6cc0e3ce286008cc4061c6ea 340 SUPERFAMILY SSF50129 1 173 4.87E-54 T 13-10-2018 IPR011032 GroES-like superfamily Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 Pfam PF01564 Spermine/spermidine synthase domain 85 265 1.0E-48 T 13-10-2018 Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 Gene3D G3DSA:3.40.50.150 82 329 2.6E-72 T 13-10-2018 Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 SUPERFAMILY SSF53335 34 312 1.66E-68 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 Gene3D G3DSA:2.30.140.10 30 81 1.3E-11 T 13-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 Pfam PF17284 Spermidine synthase tetramerisation domain 33 82 1.6E-11 T 13-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 30 313 32.634 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Spica_0253 8147a759f56f3e54cc7736dd692a164e 334 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 106 119 - T 13-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 Spica_0392 ef41462e6de132abea2e35869417df99 141 Gene3D G3DSA:3.90.1170.10 1 140 6.9E-56 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0392 ef41462e6de132abea2e35869417df99 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 40.189 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.4E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.4E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.4E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.4E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0392 ef41462e6de132abea2e35869417df99 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.1E-63 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0392 ef41462e6de132abea2e35869417df99 141 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 1.2E-52 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Spica_0392 ef41462e6de132abea2e35869417df99 141 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0392 ef41462e6de132abea2e35869417df99 141 SUPERFAMILY SSF54686 1 137 3.01E-58 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 SUPERFAMILY SSF55315 18 94 6.12E-13 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 SMART SM00967 25 100 3.5E-11 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 26 99 1.5E-13 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 Gene3D G3DSA:3.30.1330.30 14 96 1.0E-9 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 Gene3D G3DSA:3.40.1280.10 101 265 3.7E-36 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 SUPERFAMILY SSF75217 89 264 6.02E-31 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0186 b87c04ea9b867241d6a88e59658ddbfa 267 Pfam PF00588 SpoU rRNA Methylase family 118 260 1.2E-30 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 Gene3D G3DSA:1.10.10.10 7 73 3.9E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 Pfam PF07729 FCD domain 82 203 1.2E-18 T 13-10-2018 IPR011711 GntR, C-terminal Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 SMART SM00345 14 72 7.5E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 4.3E-17 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 SUPERFAMILY SSF46785 6 76 3.18E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 Gene3D G3DSA:1.20.120.530 76 219 7.3E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 SMART SM00895 82 206 4.9E-13 T 13-10-2018 IPR011711 GntR, C-terminal Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 SUPERFAMILY SSF48008 78 213 3.92E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.3E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0613 2fc00b11cee6fce9acd6144f092becd0 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.3E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 1214 1369 6.5E-25 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 Gene3D G3DSA:2.115.10.20 149 394 8.2E-7 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 Gene3D G3DSA:3.60.40.10 1154 1382 5.9E-41 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 SUPERFAMILY SSF81606 1200 1361 6.28E-8 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 Gene3D G3DSA:2.60.40.10 404 494 7.3E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 Gene3D G3DSA:1.20.1480.50 1058 1153 5.4E-5 T 13-10-2018 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 SMART SM00304 1096 1153 0.0094 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 SUPERFAMILY SSF50939 104 391 3.83E-12 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 SUPERFAMILY SSF49265 397 498 9.73E-5 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 Spica_1053 54031a2a8828c2010d6a17298d7a4437 1523 SMART SM00331 1187 1408 1.1E-34 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2573 183052a0632e6a1324d7e678cba44501 259 Gene3D G3DSA:1.10.530.10 89 226 3.2E-19 T 13-10-2018 Spica_2573 183052a0632e6a1324d7e678cba44501 259 Pfam PF01464 Transglycosylase SLT domain 97 194 6.5E-16 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Spica_2573 183052a0632e6a1324d7e678cba44501 259 SUPERFAMILY SSF53955 90 210 2.95E-23 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_0408 d54b548d92415c3684527eeaa47e9801 126 ProSitePatterns PS00054 Ribosomal protein S11 signature. 94 116 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site Spica_0408 d54b548d92415c3684527eeaa47e9801 126 Gene3D G3DSA:3.30.420.80 1 126 6.3E-50 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0408 d54b548d92415c3684527eeaa47e9801 126 PIRSF PIRSF002131 1 126 3.3E-54 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spica_0408 d54b548d92415c3684527eeaa47e9801 126 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 7 122 6.1E-56 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0408 d54b548d92415c3684527eeaa47e9801 126 Pfam PF00411 Ribosomal protein S11 16 125 9.5E-44 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spica_0408 d54b548d92415c3684527eeaa47e9801 126 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 126 31.743 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Spica_0408 d54b548d92415c3684527eeaa47e9801 126 SUPERFAMILY SSF53137 12 126 1.31E-45 T 13-10-2018 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 13-10-2018 IPR033135 ClpP, histidine active site Spica_1111 ea22df3927668545ba2ae6c94116b810 204 Gene3D G3DSA:3.90.226.10 1 202 1.1E-83 T 13-10-2018 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 198 41.061 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 Pfam PF00574 Clp protease 19 197 6.6E-82 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spica_1111 ea22df3927668545ba2ae6c94116b810 204 SUPERFAMILY SSF52096 15 198 3.79E-71 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_1111 ea22df3927668545ba2ae6c94116b810 204 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 95 106 - T 13-10-2018 IPR018215 ClpP, Ser active site Spica_1111 ea22df3927668545ba2ae6c94116b810 204 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 1.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 1.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 1.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 1.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 1.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1111 ea22df3927668545ba2ae6c94116b810 204 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 7 197 2.6E-94 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 Gene3D G3DSA:1.25.40.10 16 83 1.3E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 SUPERFAMILY SSF48452 23 155 1.52E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 Pfam PF14559 Tetratricopeptide repeat 32 91 2.4E-9 T 13-10-2018 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 SMART SM00028 19 52 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 SMART SM00028 88 121 0.047 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 SMART SM00028 122 155 0.15 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 SMART SM00028 53 86 0.31 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 Gene3D G3DSA:1.25.40.10 84 184 7.2E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1175 5b45c923c1f417357e55583938b0a01a 231 Pfam PF13432 Tetratricopeptide repeat 126 188 0.0033 T 13-10-2018 Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 Pfam PF13624 SurA N-terminal domain 81 170 1.9E-10 T 13-10-2018 Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 Gene3D G3DSA:3.10.50.40 218 333 1.3E-12 T 13-10-2018 Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 SUPERFAMILY SSF54534 238 329 5.49E-10 T 13-10-2018 Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 SUPERFAMILY SSF109998 86 262 1.02E-7 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 Gene3D G3DSA:1.10.4030.30 91 217 1.3E-12 T 13-10-2018 Spica_0808 31d5d2ae8f7958cbfeeb6a435428fdba 512 Pfam PF00639 PPIC-type PPIASE domain 250 327 6.9E-6 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 SUPERFAMILY SSF51735 77 196 1.36E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 Pfam PF02629 CoA binding domain 79 174 3.8E-13 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 Gene3D G3DSA:1.10.10.10 2 71 5.3E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 Pfam PF06971 Putative DNA-binding protein N-terminus 4 48 3.4E-7 T 13-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 SMART SM00881 74 175 1.7E-7 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 203 24.284 T 13-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 Gene3D G3DSA:3.40.50.720 72 202 7.5E-40 T 13-10-2018 Spica_2576 99d18bbbfb07fb1a8493b9003f765738 203 SUPERFAMILY SSF46785 5 74 3.45E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 PIRSF PIRSF039137 1 235 5.0E-112 T 13-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 SMART SM00382 26 213 8.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 SUPERFAMILY SSF52540 2 233 3.91E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 Pfam PF00005 ABC transporter 17 162 1.1E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0839 4e3e0f43d72c4df55c9f2baa2ee6423e 236 Gene3D G3DSA:3.40.50.300 1 235 1.7E-65 T 13-10-2018 Spica_1911 1b52132264a4052a24eb9172025f4deb 675 SMART SM00014 252 366 8.3E-4 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_1911 1b52132264a4052a24eb9172025f4deb 675 Gene3D G3DSA:1.20.144.10 223 396 1.2E-38 T 13-10-2018 Spica_1911 1b52132264a4052a24eb9172025f4deb 675 Pfam PF12951 Passenger-associated-transport-repeat 530 559 4.2E-7 T 13-10-2018 IPR013425 Autotransporter-associated beta strand repeat Spica_1911 1b52132264a4052a24eb9172025f4deb 675 SUPERFAMILY SSF51126 491 641 5.34E-9 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_1911 1b52132264a4052a24eb9172025f4deb 675 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 530 559 3.2E-7 T 13-10-2018 IPR013425 Autotransporter-associated beta strand repeat Spica_1911 1b52132264a4052a24eb9172025f4deb 675 Pfam PF01569 PAP2 superfamily 263 362 4.6E-12 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_1911 1b52132264a4052a24eb9172025f4deb 675 SUPERFAMILY SSF48317 254 367 3.14E-24 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily Spica_1689 f99601013f46c575770b184ef27130c7 147 SUPERFAMILY SSF89447 3 140 1.87E-39 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Spica_1689 f99601013f46c575770b184ef27130c7 147 Gene3D G3DSA:2.40.330.20 1 146 6.0E-44 T 13-10-2018 IPR038619 MraZ superfamily Spica_1689 f99601013f46c575770b184ef27130c7 147 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 4 132 1.0E-34 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Spica_1689 f99601013f46c575770b184ef27130c7 147 Pfam PF02381 MraZ protein, putative antitoxin-like 77 142 1.0E-20 T 13-10-2018 IPR020603 MraZ domain Spica_1689 f99601013f46c575770b184ef27130c7 147 Pfam PF02381 MraZ protein, putative antitoxin-like 3 74 5.7E-16 T 13-10-2018 IPR020603 MraZ domain Spica_1689 f99601013f46c575770b184ef27130c7 147 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 4 144 1.1E-37 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Spica_1689 f99601013f46c575770b184ef27130c7 147 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 147 43.135 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Gene3D G3DSA:1.25.40.10 370 637 3.9E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Gene3D G3DSA:1.25.40.10 266 344 2.3E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Gene3D G3DSA:1.25.40.10 143 265 1.2E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Pfam PF13432 Tetratricopeptide repeat 12 72 2.5E-6 T 13-10-2018 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Pfam PF13432 Tetratricopeptide repeat 188 242 1.4E-5 T 13-10-2018 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SUPERFAMILY SSF48452 7 177 4.67E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SUPERFAMILY SSF48452 185 500 3.04E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SUPERFAMILY SSF48452 467 631 2.02E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Gene3D G3DSA:1.25.40.10 6 141 1.9E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 218 251 480.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 41 74 8.3 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 184 217 0.0072 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 293 326 99.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 504 537 36.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 396 429 33.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 109 142 8.6E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 75 108 0.13 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 SMART SM00028 572 605 98.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1146 cd474eff02dd7d40983e9b86a6b0439b 649 Pfam PF14559 Tetratricopeptide repeat 86 142 1.0E-5 T 13-10-2018 Spica_0645 90e831d3cfeec8ef515dd32059eb5ddc 475 SUPERFAMILY SSF52540 207 371 7.36E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0645 90e831d3cfeec8ef515dd32059eb5ddc 475 Pfam PF05673 Protein of unknown function (DUF815) 205 468 9.3E-85 T 13-10-2018 IPR008533 Domain of unknown function DUF815 Spica_0645 90e831d3cfeec8ef515dd32059eb5ddc 475 Gene3D G3DSA:3.40.50.300 232 378 1.8E-12 T 13-10-2018 Spica_1742 b39b069b57f900a6e7e827cd0f412d0b 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_1742 b39b069b57f900a6e7e827cd0f412d0b 487 Pfam PF05598 Transposase domain (DUF772) 53 123 2.1E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_2231 b39b069b57f900a6e7e827cd0f412d0b 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_2231 b39b069b57f900a6e7e827cd0f412d0b 487 Pfam PF05598 Transposase domain (DUF772) 53 123 2.1E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 Pfam PF14849 YidC periplasmic domain 86 337 1.7E-17 T 13-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 5 340 2.9E-29 T 13-10-2018 IPR028053 Membrane insertase YidC, N-terminal Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 Gene3D G3DSA:2.70.98.90 82 340 3.5E-12 T 13-10-2018 IPR038221 YidC, periplasmic domain superfamily Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 583 16.102 T 13-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 PRINTS PR00701 60kDa inner membrane protein signature 268 283 6.4E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 PRINTS PR00701 60kDa inner membrane protein signature 444 467 6.4E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 PRINTS PR00701 60kDa inner membrane protein signature 91 112 6.4E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 PRINTS PR00701 60kDa inner membrane protein signature 180 200 6.4E-15 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 Pfam PF02096 60Kd inner membrane protein 383 581 7.1E-61 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_0007 7d603f7f940cae337c9c7986663bcb5a 605 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 382 581 9.2E-64 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Gene3D G3DSA:3.20.20.450 423 685 2.6E-77 T 13-10-2018 IPR035919 EAL domain superfamily Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Pfam PF00563 EAL domain 441 679 9.2E-60 T 13-10-2018 IPR001633 EAL domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Pfam PF00072 Response regulator receiver domain 6 116 6.7E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SMART SM00448 4 116 4.0E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SUPERFAMILY SSF141868 440 683 1.44E-67 T 13-10-2018 IPR035919 EAL domain superfamily Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SMART SM00052 434 684 3.1E-72 T 13-10-2018 IPR001633 EAL domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SMART SM00267 250 422 4.1E-48 T 13-10-2018 IPR000160 GGDEF domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Gene3D G3DSA:3.30.70.270 254 422 1.0E-48 T 13-10-2018 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Gene3D G3DSA:3.40.50.2300 1 128 5.9E-33 T 13-10-2018 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Pfam PF00989 PAS fold 136 247 1.1E-10 T 13-10-2018 IPR013767 PAS fold GO:0006355 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SUPERFAMILY SSF55785 125 248 1.64E-14 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 131 253 1.1E-12 T 13-10-2018 IPR000014 PAS domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SUPERFAMILY SSF55073 266 423 2.9E-43 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SMART SM00091 134 200 2.1E-8 T 13-10-2018 IPR000014 PAS domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Gene3D G3DSA:3.30.450.20 129 253 1.5E-17 T 13-10-2018 Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 SUPERFAMILY SSF52172 3 133 2.85E-34 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 Pfam PF00990 Diguanylate cyclase, GGDEF domain 262 418 4.3E-38 T 13-10-2018 IPR000160 GGDEF domain Spica_2064 74bc4bfcccb51560d96785a7fa3bd4c4 686 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 259 422 9.2E-39 T 13-10-2018 IPR000160 GGDEF domain Spica_2021 fb5e222febc3abc944df957a7d9aef4f 307 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 4.2E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2021 fb5e222febc3abc944df957a7d9aef4f 307 Gene3D G3DSA:1.10.10.10 9 92 1.0E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2021 fb5e222febc3abc944df957a7d9aef4f 307 PIRSF PIRSF030050 5 307 9.7E-128 T 13-10-2018 IPR016943 Uncharacterised conserved protein UCP030050, HTH transcriptional regulator, BH1869 Spica_2021 fb5e222febc3abc944df957a7d9aef4f 307 SMART SM00418 18 109 5.1E-4 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_2021 fb5e222febc3abc944df957a7d9aef4f 307 SUPERFAMILY SSF46785 18 217 3.18E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Gene3D G3DSA:3.30.300.10 105 382 1.4E-172 T 13-10-2018 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 122 132 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Gene3D G3DSA:3.30.300.10 8 241 1.4E-172 T 13-10-2018 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 SUPERFAMILY SSF55973 5 110 7.85E-45 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Gene3D G3DSA:3.30.300.10 13 278 1.4E-172 T 13-10-2018 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 240 377 4.6E-68 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 SUPERFAMILY SSF55973 240 387 1.77E-69 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 388 3.9E-187 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 7.0E-42 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 266 274 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 SUPERFAMILY SSF55973 119 239 1.72E-48 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 388 58.119 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 PIRSF PIRSF000497 1 389 5.2E-175 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_2858 67daaa6e02914b7ca72b0852a8361470 390 Pfam PF02772 S-adenosylmethionine synthetase, central domain 120 238 2.1E-45 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Spica_0148 2d828417168426028677871eb9620e41 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 281 2.2E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0148 2d828417168426028677871eb9620e41 294 SUPERFAMILY SSF161098 54 281 1.96E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0148 2d828417168426028677871eb9620e41 294 Gene3D G3DSA:1.10.3720.10 50 291 1.3E-70 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2395 195f5bcc2dfc2703e3f30307a80b981d 311 Pfam PF04754 Putative transposase, YhgA-like 3 199 6.5E-31 T 13-10-2018 IPR006842 Transposase (putative), YhgA-like Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 Gene3D G3DSA:3.40.190.80 146 260 5.6E-27 T 13-10-2018 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 Gene3D G3DSA:3.30.540.10 1 137 5.8E-40 T 13-10-2018 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 SUPERFAMILY SSF56655 4 257 2.49E-66 T 13-10-2018 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 2.4E-35 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 155 181 6.2E-7 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 103 122 6.2E-7 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 PRINTS PR01959 SuhB family inositol monophosphatase signature 197 209 6.2E-7 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Spica_0194 0cdc7cc0072cc45b1e5b64225e94c09e 265 Pfam PF00459 Inositol monophosphatase family 4 257 1.2E-50 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Spica_0712 e88ca988f9bb50704f594645cda2f711 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 12.328 T 13-10-2018 IPR022907 VapC family GO:0004540 Spica_0712 e88ca988f9bb50704f594645cda2f711 131 Pfam PF01850 PIN domain 1 124 2.4E-16 T 13-10-2018 IPR002716 PIN domain Spica_0712 e88ca988f9bb50704f594645cda2f711 131 Gene3D G3DSA:3.40.50.1010 1 128 8.0E-43 T 13-10-2018 Spica_0712 e88ca988f9bb50704f594645cda2f711 131 SUPERFAMILY SSF88723 1 125 2.45E-17 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0325 28c058872697971560d64926c166ad99 104 Gene3D G3DSA:3.30.300.130 1 102 4.2E-28 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_0325 28c058872697971560d64926c166ad99 104 SUPERFAMILY SSF117916 3 100 2.22E-26 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_0325 28c058872697971560d64926c166ad99 104 Pfam PF01883 Iron-sulfur cluster assembly protein 7 74 2.3E-14 T 13-10-2018 IPR002744 MIP18 family-like Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 SUPERFAMILY SSF46689 349 462 3.9E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 SMART SM00448 2 113 4.5E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 SMART SM00382 160 303 5.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 SUPERFAMILY SSF52540 139 379 3.71E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 SUPERFAMILY SSF52172 2 184 5.12E-41 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Pfam PF00158 Sigma-54 interaction domain 140 307 8.0E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Gene3D G3DSA:3.40.50.2300 1 130 2.4E-35 T 13-10-2018 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Gene3D G3DSA:1.10.10.60 412 465 1.6E-11 T 13-10-2018 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Gene3D G3DSA:3.40.50.300 131 310 2.4E-64 T 13-10-2018 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Gene3D G3DSA:1.10.8.60 311 373 1.0E-20 T 13-10-2018 Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_2580 09f63e7b00dbf7e9745b9117db27b241 466 Pfam PF00072 Response regulator receiver domain 4 111 2.6E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1507 02aef9024ba246b8d8834be503773af4 343 Pfam PF01263 Aldose 1-epimerase 18 338 2.0E-93 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Spica_1507 02aef9024ba246b8d8834be503773af4 343 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 175 184 - T 13-10-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 Spica_1507 02aef9024ba246b8d8834be503773af4 343 SUPERFAMILY SSF74650 6 341 3.96E-115 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_1507 02aef9024ba246b8d8834be503773af4 343 PIRSF PIRSF005096 1 343 1.2E-124 T 13-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 Spica_1507 02aef9024ba246b8d8834be503773af4 343 Gene3D G3DSA:2.70.98.10 1 342 2.5E-126 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 Pfam PF01168 Alanine racemase, N-terminal domain 9 227 9.8E-19 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 Gene3D G3DSA:3.20.20.10 1 229 7.2E-70 T 13-10-2018 IPR029066 PLP-binding barrel Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 228 24.763 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 227 1.1E-50 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 SUPERFAMILY SSF51419 1 226 8.29E-62 T 13-10-2018 IPR029066 PLP-binding barrel Spica_1585 7797f7a57f3f91ce2a00b765fee3d875 229 PIRSF PIRSF004848 1 229 7.3E-62 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Spica_0012 47506488be83a9220fe9347250f5d938 230 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 202 9.6E-24 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Spica_0012 47506488be83a9220fe9347250f5d938 230 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 226 9.1E-60 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Spica_0012 47506488be83a9220fe9347250f5d938 230 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 222 34.098 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Spica_0012 47506488be83a9220fe9347250f5d938 230 PIRSF PIRSF005917 1 229 5.6E-87 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Spica_0012 47506488be83a9220fe9347250f5d938 230 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 81 92 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 Spica_0012 47506488be83a9220fe9347250f5d938 230 Gene3D G3DSA:3.40.1010.10 1 110 1.6E-40 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Spica_0012 47506488be83a9220fe9347250f5d938 230 Gene3D G3DSA:3.30.950.10 111 227 3.5E-28 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Spica_0012 47506488be83a9220fe9347250f5d938 230 SUPERFAMILY SSF53790 2 217 3.4E-66 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Spica_1764 221db970b757f7148caddce55303ed5d 287 SUPERFAMILY SSF53335 11 271 6.33E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1764 221db970b757f7148caddce55303ed5d 287 PIRSF PIRSF000398 6 278 2.2E-55 T 13-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 Spica_1764 221db970b757f7148caddce55303ed5d 287 Gene3D G3DSA:1.10.1020.10 70 170 4.4E-34 T 13-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 Spica_1764 221db970b757f7148caddce55303ed5d 287 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 15 31 6.0E-11 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_1764 221db970b757f7148caddce55303ed5d 287 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 40 54 6.0E-11 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_1764 221db970b757f7148caddce55303ed5d 287 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 63 76 6.0E-11 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_1764 221db970b757f7148caddce55303ed5d 287 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 193 205 6.0E-11 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_1764 221db970b757f7148caddce55303ed5d 287 Gene3D G3DSA:3.40.50.150 13 252 4.4E-34 T 13-10-2018 Spica_2849 00b26b16b10a167b268a776997623759 281 SUPERFAMILY SSF46689 5 80 7.17E-21 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2849 00b26b16b10a167b268a776997623759 281 Gene3D G3DSA:3.40.50.10490 96 279 6.5E-41 T 13-10-2018 Spica_2849 00b26b16b10a167b268a776997623759 281 SUPERFAMILY SSF53697 101 262 4.28E-33 T 13-10-2018 Spica_2849 00b26b16b10a167b268a776997623759 281 Gene3D G3DSA:1.10.10.10 2 79 1.4E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2849 00b26b16b10a167b268a776997623759 281 Pfam PF01380 SIS domain 131 255 2.3E-13 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Spica_2849 00b26b16b10a167b268a776997623759 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 79 2.3E-20 T 13-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Spica_2758 c06dce889ba41f888c7c726267afc436 267 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 10 264 2.6E-77 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Spica_2758 c06dce889ba41f888c7c726267afc436 267 Pfam PF13277 YmdB-like protein 12 263 5.1E-97 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Spica_2758 c06dce889ba41f888c7c726267afc436 267 SUPERFAMILY SSF56300 10 265 7.59E-72 T 13-10-2018 Spica_2758 c06dce889ba41f888c7c726267afc436 267 Gene3D G3DSA:3.60.21.10 9 266 1.7E-102 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_2758 c06dce889ba41f888c7c726267afc436 267 PIRSF PIRSF004789 8 266 3.2E-86 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 SUPERFAMILY SSF56752 3 291 1.83E-71 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 ProSitePatterns PS00770 Aminotransferases class-IV signature. 180 209 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 Gene3D G3DSA:3.20.10.10 125 293 2.6E-49 T 13-10-2018 Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 Pfam PF01063 Amino-transferase class IV 32 253 9.4E-46 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 Gene3D G3DSA:3.30.470.10 1 118 4.2E-29 T 13-10-2018 Spica_1209 eaf2276c58f30323e41fdbc6c1b3ee56 299 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 7 287 8.7E-93 T 13-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 TIGRFAM TIGR00029 S20: ribosomal protein bS20 4 86 1.4E-21 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 15 85 1.0E-11 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 Pfam PF01649 Ribosomal protein S20 5 85 1.1E-23 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 SUPERFAMILY SSF46992 6 86 1.01E-25 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 86 15.626 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1611 7bf2b99701269285e73dc50d4d8f8bc1 90 Gene3D G3DSA:1.20.58.110 2 90 3.6E-24 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_2369 2a36827719e45a2e53c11e15dff3f6b9 193 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 5 185 1.2E-49 T 13-10-2018 IPR006287 Protein/nucleic acid deglycase DJ-1 Reactome: R-HSA-3899300 Spica_2369 2a36827719e45a2e53c11e15dff3f6b9 193 Gene3D G3DSA:3.40.50.880 1 192 1.1E-54 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2369 2a36827719e45a2e53c11e15dff3f6b9 193 Pfam PF01965 DJ-1/PfpI family 3 172 1.6E-45 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 Spica_2369 2a36827719e45a2e53c11e15dff3f6b9 193 SUPERFAMILY SSF52317 3 189 6.88E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 SUPERFAMILY SSF55785 26 112 6.47E-9 T 13-10-2018 IPR035965 PAS domain superfamily Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 Pfam PF07568 Histidine kinase 173 244 1.1E-22 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 271 369 1.7E-6 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 SMART SM00091 39 106 0.0022 T 13-10-2018 IPR000014 PAS domain Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 Gene3D G3DSA:3.30.450.20 52 225 2.1E-12 T 13-10-2018 Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 Gene3D G3DSA:3.30.565.10 230 374 7.0E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 SUPERFAMILY SSF55874 235 359 3.01E-11 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1581 88f8fa784af58b62db83d38e02fa833d 384 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 42 160 2.7E-6 T 13-10-2018 IPR000014 PAS domain Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 Gene3D G3DSA:3.40.50.1260 7 417 4.7E-154 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 SUPERFAMILY SSF53748 2 417 1.65E-152 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 14 24 - T 13-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PIRSF PIRSF000724 1 419 1.9E-146 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 Gene3D G3DSA:3.40.50.1260 194 410 4.7E-154 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 419 39.896 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 129 144 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 396 413 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 9 25 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 215 234 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 30 52 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 192 214 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 373 384 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 161 183 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 PRINTS PR00477 Phosphoglycerate kinase family signature 337 362 4.8E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1826 25c08ab518b73d80f0c2c6dea7e169e0 419 Pfam PF00162 Phosphoglycerate kinase 5 410 4.5E-153 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_2688 56078b482270fdc8192d8ff0db213033 466 Gene3D G3DSA:3.30.499.20 4 286 1.7E-90 T 13-10-2018 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 209 222 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 286 300 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 133 148 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 397 410 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 108 116 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 119 132 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 195 208 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 PRINTS PR00415 Aconitase family signature 341 352 2.1E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 SUPERFAMILY SSF53732 1 464 5.36E-154 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 Gene3D G3DSA:3.30.499.10 323 464 3.8E-48 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 ProSitePatterns PS01244 Aconitase family signature 2. 397 410 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 465 54.363 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 464 1.1E-182 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 ProSitePatterns PS00450 Aconitase family signature 1. 337 353 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Spica_2688 56078b482270fdc8192d8ff0db213033 466 Pfam PF00330 Aconitase family (aconitate hydratase) 7 456 3.4E-147 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 SMART SM00387 550 660 5.5E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 552 658 3.2E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 618 1.4E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 639 1.4E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 657 1.4E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 604 1.4E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 Gene3D G3DSA:1.10.287.130 347 507 3.6E-9 T 13-10-2018 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 Gene3D G3DSA:3.30.565.10 513 661 2.8E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 SUPERFAMILY SSF55874 513 659 6.42E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 SUPERFAMILY SSF47384 349 384 2.55E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2839 ede31dded506746aac07cdde6c6da3d8 662 Pfam PF00512 His Kinase A (phospho-acceptor) domain 355 399 9.9E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Gene3D G3DSA:3.20.20.70 450 839 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Pfam PF01493 GXGXG motif 1300 1487 4.4E-84 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 SUPERFAMILY SSF51395 468 1249 6.11E-246 T 13-10-2018 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Pfam PF04898 Glutamate synthase central domain 479 771 1.5E-106 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Gene3D G3DSA:3.60.20.10 21 565 0.0 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Pfam PF01645 Conserved region in glutamate synthase 841 1217 8.0E-151 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Gene3D G3DSA:3.20.20.70 503 1233 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 SUPERFAMILY SSF56235 21 448 9.83E-142 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Pfam PF00310 Glutamine amidotransferases class-II 21 445 1.3E-170 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 Gene3D G3DSA:2.160.20.60 1272 1543 2.6E-113 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Spica_1859 c5e080b256a4540c05ef2eb356c4422e 1557 SUPERFAMILY SSF69336 1271 1535 2.62E-96 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SUPERFAMILY SSF55785 307 414 6.63E-28 T 13-10-2018 IPR035965 PAS domain superfamily Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Pfam PF00990 Diguanylate cyclase, GGDEF domain 427 583 1.1E-52 T 13-10-2018 IPR000160 GGDEF domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Pfam PF13426 PAS domain 313 415 3.1E-14 T 13-10-2018 IPR000014 PAS domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SMART SM00052 598 862 3.4E-93 T 13-10-2018 IPR001633 EAL domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Gene3D G3DSA:3.30.70.270 429 595 1.3E-62 T 13-10-2018 Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 423 587 1.2E-45 T 13-10-2018 IPR000160 GGDEF domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 304 423 4.8E-19 T 13-10-2018 IPR000014 PAS domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SMART SM00091 302 368 3.6E-9 T 13-10-2018 IPR000014 PAS domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Gene3D G3DSA:3.20.20.450 599 870 5.7E-87 T 13-10-2018 IPR035919 EAL domain superfamily Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Gene3D G3DSA:3.30.450.20 293 428 1.9E-32 T 13-10-2018 Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Pfam PF05228 CHASE4 domain 57 196 2.2E-26 T 13-10-2018 IPR007892 CHASE4 Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SMART SM00267 416 588 7.7E-73 T 13-10-2018 IPR000160 GGDEF domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SUPERFAMILY SSF141868 604 869 1.26E-73 T 13-10-2018 IPR035919 EAL domain superfamily Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 Pfam PF00563 EAL domain 605 857 4.9E-61 T 13-10-2018 IPR001633 EAL domain Spica_1891 fd9d6d80850d02ba934f6ea2cb1b1273 896 SUPERFAMILY SSF55073 432 588 1.8E-52 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 SUPERFAMILY SSF142019 88 297 3.01E-60 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 4 442 6.7E-147 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 451 138.716 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Pfam PF13237 4Fe-4S dicluster domain 371 423 2.1E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 SUPERFAMILY SSF46548 329 441 2.2E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 129 277 9.6E-55 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Gene3D G3DSA:3.40.50.11540 134 287 9.7E-20 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 412 423 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 105 1.1E-30 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain Spica_0651 090962fc9bab2a2a16150d077d3b8d22 451 Gene3D G3DSA:3.30.70.20 338 430 1.2E-6 T 13-10-2018 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 SMART SM00729 141 363 5.1E-58 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 145 165 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Pfam PF01938 TRAM domain 374 426 2.4E-10 T 13-10-2018 IPR002792 TRAM domain Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 430 1.4E-137 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Pfam PF04055 Radical SAM superfamily 145 320 1.8E-28 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 437 60.078 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 SUPERFAMILY SSF102114 139 368 2.35E-57 T 13-10-2018 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Gene3D G3DSA:3.40.50.12160 1 137 8.9E-31 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Gene3D G3DSA:3.80.30.20 139 377 3.6E-84 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 Pfam PF00919 Uncharacterized protein family UPF0004 3 100 9.3E-29 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Spica_1136 2a82568a139f1ab3e14c5ad732215130 442 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 2 434 1.6E-155 T 13-10-2018 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 Pfam PF07690 Major Facilitator Superfamily 5 202 2.0E-28 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 PRINTS PR01035 Tetracycline resistance protein signature 5 24 7.1E-10 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 PRINTS PR01035 Tetracycline resistance protein signature 301 324 7.1E-10 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 PRINTS PR01035 Tetracycline resistance protein signature 93 115 7.1E-10 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 PRINTS PR01035 Tetracycline resistance protein signature 63 84 7.1E-10 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 Pfam PF00083 Sugar (and other) transporter 208 345 1.0E-5 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 SUPERFAMILY SSF103473 4 358 1.4E-60 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 Gene3D G3DSA:1.20.1250.20 2 167 7.3E-36 T 13-10-2018 Spica_1887 57cc08a01cf67030b9f16d7183ff2053 359 Gene3D G3DSA:1.20.1250.20 168 359 4.5E-30 T 13-10-2018 Spica_0565 886e591d8d413101f455c22f39c02b50 999 SUPERFAMILY SSF57997 174 406 6.54E-5 T 13-10-2018 Spica_0565 886e591d8d413101f455c22f39c02b50 999 SUPERFAMILY SSF52540 2 927 4.31E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0565 886e591d8d413101f455c22f39c02b50 999 PIRSF PIRSF005719 411 940 1.4E-104 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein Spica_0565 886e591d8d413101f455c22f39c02b50 999 PIRSF PIRSF005719 1 509 8.6E-111 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein Spica_0565 886e591d8d413101f455c22f39c02b50 999 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 925 1.7E-72 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Spica_0565 886e591d8d413101f455c22f39c02b50 999 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 934 19.137 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Spica_0565 886e591d8d413101f455c22f39c02b50 999 Gene3D G3DSA:1.20.5.340 336 421 5.5E-5 T 13-10-2018 Spica_0565 886e591d8d413101f455c22f39c02b50 999 Gene3D G3DSA:3.40.50.300 1 251 1.0E-57 T 13-10-2018 Spica_0565 886e591d8d413101f455c22f39c02b50 999 Gene3D G3DSA:3.40.50.300 651 938 7.6E-48 T 13-10-2018 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 4 799 0.0 T 13-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 234 349 2.9E-11 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SUPERFAMILY SSF81923 3 139 8.63E-40 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SMART SM01086 720 809 2.5E-18 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Gene3D G3DSA:3.40.50.300 506 719 7.1E-79 T 13-10-2018 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Gene3D G3DSA:1.10.1780.10 2 140 3.2E-34 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Gene3D G3DSA:1.10.8.60 720 812 1.5E-17 T 13-10-2018 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 628 646 4.7E-40 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 557 575 4.7E-40 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 661 675 4.7E-40 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 617 4.7E-40 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Pfam PF07724 AAA domain (Cdc48 subfamily) 552 713 7.8E-48 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 799 2.4E-15 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 324 336 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 14 58 2.0E-7 T 13-10-2018 IPR004176 Clp, N-terminal Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SMART SM00382 553 700 3.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SMART SM00382 229 373 6.3E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SUPERFAMILY SSF52540 190 441 2.1E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Gene3D G3DSA:3.40.50.300 188 378 1.1E-64 T 13-10-2018 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 584 602 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 Gene3D G3DSA:1.10.8.60 379 437 1.5E-27 T 13-10-2018 Spica_2015 ff98161df3b21e8b05e43214bfcb0ec4 813 SUPERFAMILY SSF52540 504 781 1.43E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Gene3D G3DSA:3.30.565.10 626 756 2.5E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 SUPERFAMILY SSF55874 632 748 6.55E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Pfam PF07730 Histidine kinase 560 628 6.5E-7 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Gene3D G3DSA:3.40.50.2300 5 261 4.3E-44 T 13-10-2018 Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 SUPERFAMILY SSF53822 5 288 1.57E-40 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 668 753 6.0E-10 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 SMART SM00387 666 756 6.5E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Pfam PF13377 Periplasmic binding protein-like domain 125 288 3.2E-27 T 13-10-2018 Spica_0307 ab6f09998bd68a09ee1b9bd4306f279a 756 Gene3D G3DSA:3.40.50.2300 117 247 4.3E-44 T 13-10-2018 Spica_2315 66f57a8cab5693f2ceea1ae0c2c3a8da 317 SUPERFAMILY SSF52540 14 286 3.0E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2315 66f57a8cab5693f2ceea1ae0c2c3a8da 317 Gene3D G3DSA:3.40.50.300 23 188 1.7E-37 T 13-10-2018 Spica_2315 66f57a8cab5693f2ceea1ae0c2c3a8da 317 PIRSF PIRSF002849 1 316 1.6E-113 T 13-10-2018 Spica_2315 66f57a8cab5693f2ceea1ae0c2c3a8da 317 Gene3D G3DSA:1.10.8.300 203 311 1.1E-31 T 13-10-2018 Spica_2315 66f57a8cab5693f2ceea1ae0c2c3a8da 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 170 4.9E-55 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SUPERFAMILY SSF54980 398 475 4.68E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SMART SM00889 474 592 6.0E-25 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Gene3D G3DSA:3.40.50.300 1 286 5.2E-107 T 13-10-2018 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Gene3D G3DSA:2.40.30.10 287 399 1.7E-35 T 13-10-2018 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Hamap MF_00054_B Elongation factor G [fusA]. 1 674 94.407 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 PRINTS PR00315 GTP-binding elongation factor signature 89 100 9.6E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 PRINTS PR00315 GTP-binding elongation factor signature 73 83 9.6E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 PRINTS PR00315 GTP-binding elongation factor signature 125 134 9.6E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 PRINTS PR00315 GTP-binding elongation factor signature 7 20 9.6E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 PRINTS PR00315 GTP-binding elongation factor signature 53 61 9.6E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Pfam PF00009 Elongation factor Tu GTP binding domain 4 275 3.7E-67 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SUPERFAMILY SSF54211 473 593 3.79E-26 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SUPERFAMILY SSF52540 3 275 7.83E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Pfam PF00679 Elongation factor G C-terminus 595 673 2.8E-24 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Pfam PF03144 Elongation factor Tu domain 2 318 384 1.2E-11 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SUPERFAMILY SSF50447 260 398 7.07E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Gene3D G3DSA:3.30.230.10 478 672 8.3E-59 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SMART SM00838 594 675 8.4E-24 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 175 7.5E-31 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Pfam PF14492 Elongation Factor G, domain II 398 471 3.5E-29 T 13-10-2018 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Pfam PF03764 Elongation factor G, domain IV 473 591 6.6E-23 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Gene3D G3DSA:3.30.70.870 400 477 3.8E-27 T 13-10-2018 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 672 3.3E-252 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 SUPERFAMILY SSF54980 595 672 3.69E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_0853 6fffccb4eafaa1bae87910d3394b9dd6 675 Gene3D G3DSA:3.30.70.240 598 668 8.3E-59 T 13-10-2018 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00267 604 776 2.6E-63 T 13-10-2018 IPR000160 GGDEF domain Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 304 337 56.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 264 297 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 161 194 55.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 344 377 93.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 224 257 5.1E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00028 121 154 24.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 613 774 3.3E-44 T 13-10-2018 IPR000160 GGDEF domain Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Gene3D G3DSA:1.25.40.10 52 207 3.1E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Gene3D G3DSA:3.30.450.40 410 609 6.0E-28 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SUPERFAMILY SSF48452 224 408 3.48E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SUPERFAMILY SSF48452 65 199 1.55E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SUPERFAMILY SSF55073 620 778 6.28E-50 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SUPERFAMILY SSF55781 424 607 1.13E-25 T 13-10-2018 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Pfam PF00990 Diguanylate cyclase, GGDEF domain 615 771 6.8E-48 T 13-10-2018 IPR000160 GGDEF domain Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 SMART SM00065 441 591 2.5E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Pfam PF13185 GAF domain 440 582 8.1E-13 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Gene3D G3DSA:3.30.70.270 610 779 4.0E-55 T 13-10-2018 Spica_0879 6f8f65b05b4423f5617801a3eb7480f8 779 Gene3D G3DSA:1.25.40.10 221 376 3.3E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 SUPERFAMILY SSF52467 215 377 8.09E-54 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Gene3D G3DSA:3.40.50.970 379 583 3.7E-68 T 13-10-2018 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Gene3D G3DSA:3.40.50.1220 212 376 2.1E-56 T 13-10-2018 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 221 354 6.4E-45 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Gene3D G3DSA:3.40.50.970 1 179 2.5E-70 T 13-10-2018 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 3.9E-57 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 582 9.4E-215 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 SUPERFAMILY SSF52518 386 582 5.14E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 409 559 3.5E-49 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 446 465 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Spica_2671 a5513601eb3f369bd86c8e7366077e34 583 SUPERFAMILY SSF52518 2 177 1.0E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1018 b148c8309c3d68a757b64215252b416c 175 SUPERFAMILY SSF55021 2 77 2.68E-11 T 13-10-2018 Spica_1018 b148c8309c3d68a757b64215252b416c 175 SUPERFAMILY SSF55021 90 169 1.4E-10 T 13-10-2018 Spica_1018 b148c8309c3d68a757b64215252b416c 175 Pfam PF13740 ACT domain 3 77 1.6E-15 T 13-10-2018 Spica_1018 b148c8309c3d68a757b64215252b416c 175 Gene3D G3DSA:3.30.70.260 1 82 1.2E-19 T 13-10-2018 Spica_1018 b148c8309c3d68a757b64215252b416c 175 PIRSF PIRSF028103 1 175 4.9E-41 T 13-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 Spica_1018 b148c8309c3d68a757b64215252b416c 175 Gene3D G3DSA:3.30.70.260 88 172 7.0E-18 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Gene3D G3DSA:2.70.150.20 217 329 1.1E-42 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 156 741 2.3E-200 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Gene3D G3DSA:3.40.50.1000 406 684 7.2E-99 T 13-10-2018 IPR023214 HAD superfamily Spica_2518 484b185590c202489fb6efaed434aa2c 758 Pfam PF00702 haloacid dehalogenase-like hydrolase 420 646 3.3E-49 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Gene3D G3DSA:3.30.70.100 2 86 5.7E-21 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 SUPERFAMILY SSF56784 422 739 5.34E-67 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2518 484b185590c202489fb6efaed434aa2c 758 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 137 742 1.6E-186 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 438 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 274 288 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 655 667 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 568 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 589 2.4E-32 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 SUPERFAMILY SSF81653 226 324 3.27E-31 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Pfam PF00122 E1-E2 ATPase 225 403 6.5E-59 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Pfam PF00403 Heavy-metal-associated domain 6 67 2.1E-14 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spica_2518 484b185590c202489fb6efaed434aa2c 758 SUPERFAMILY SSF81665 188 731 2.75E-13 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Spica_2518 484b185590c202489fb6efaed434aa2c 758 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 196 710 2.2E-99 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 194 213 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 48 68 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 214 232 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 347 361 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 141 160 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 407 422 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 PRINTS PR00943 Copper-transporting ATPase signature 609 626 2.0E-19 T 13-10-2018 Spica_2518 484b185590c202489fb6efaed434aa2c 758 Gene3D G3DSA:3.40.1110.10 435 564 7.2E-99 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Spica_2518 484b185590c202489fb6efaed434aa2c 758 SUPERFAMILY SSF55008 2 74 6.81E-20 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Spica_2518 484b185590c202489fb6efaed434aa2c 758 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 426 432 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 PIRSF PIRSF003128 1 562 1.2E-167 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 Gene3D G3DSA:3.40.50.300 250 559 6.6E-54 T 13-10-2018 Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 513 2.3E-17 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 Gene3D G3DSA:3.40.50.300 1 249 6.0E-43 T 13-10-2018 Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 SUPERFAMILY SSF52540 1 519 4.23E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1803 f93272dbc29c92b885d16d859b3d4653 565 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 557 5.4E-177 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Spica_1980 742867ce9f68f7d5fe733e7c7f27ef9b 333 Gene3D G3DSA:3.20.20.70 1 238 1.4E-60 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1980 742867ce9f68f7d5fe733e7c7f27ef9b 333 PIRSF PIRSF006621 1 316 1.8E-60 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spica_1980 742867ce9f68f7d5fe733e7c7f27ef9b 333 Pfam PF01207 Dihydrouridine synthase (Dus) 7 258 3.4E-56 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Spica_1980 742867ce9f68f7d5fe733e7c7f27ef9b 333 SUPERFAMILY SSF51395 4 309 1.81E-53 T 13-10-2018 Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 Pfam PF00557 Metallopeptidase family M24 156 363 1.6E-42 T 13-10-2018 IPR000994 Peptidase M24 Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 PRINTS PR00599 Methionine aminopeptidase-1 signature 331 343 1.9E-5 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 PRINTS PR00599 Methionine aminopeptidase-1 signature 302 314 1.9E-5 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 PRINTS PR00599 Methionine aminopeptidase-1 signature 233 249 1.9E-5 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 SUPERFAMILY SSF55920 153 371 8.77E-54 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Spica_2719 46da7463f2bbe9a7e81f798b802c275c 379 Gene3D G3DSA:3.90.230.10 147 376 1.8E-56 T 13-10-2018 Spica_0507 9b711ca7ee4f876a95cc891fac2b439c 332 Gene3D G3DSA:3.40.50.720 8 306 1.4E-89 T 13-10-2018 Spica_0507 9b711ca7ee4f876a95cc891fac2b439c 332 SUPERFAMILY SSF51735 2 318 8.05E-86 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0507 9b711ca7ee4f876a95cc891fac2b439c 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 312 5.2E-68 T 13-10-2018 IPR016040 NAD(P)-binding domain Spica_0507 9b711ca7ee4f876a95cc891fac2b439c 332 Gene3D G3DSA:3.90.25.10 189 317 1.4E-89 T 13-10-2018 Spica_0507 9b711ca7ee4f876a95cc891fac2b439c 332 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 8 304 1.3E-156 T 13-10-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family Spica_0459 360c42ead5cedc93614771fde063ec89 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 84 1.0E-17 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Spica_0459 360c42ead5cedc93614771fde063ec89 97 SUPERFAMILY SSF75471 1 92 5.36E-21 T 13-10-2018 IPR035920 YhbY-like superfamily Spica_0459 360c42ead5cedc93614771fde063ec89 97 SMART SM01103 2 84 7.7E-26 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Spica_0459 360c42ead5cedc93614771fde063ec89 97 Gene3D G3DSA:3.30.110.60 1 97 2.8E-27 T 13-10-2018 IPR035920 YhbY-like superfamily Spica_0459 360c42ead5cedc93614771fde063ec89 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 4.0E-15 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 Spica_0880 a17d43771b7cf150dc306651f775b046 145 SUPERFAMILY SSF52172 23 144 2.7E-32 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0880 a17d43771b7cf150dc306651f775b046 145 Pfam PF00072 Response regulator receiver domain 27 139 1.0E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0880 a17d43771b7cf150dc306651f775b046 145 Gene3D G3DSA:3.40.50.2300 18 144 2.3E-34 T 13-10-2018 Spica_0880 a17d43771b7cf150dc306651f775b046 145 SMART SM00448 25 139 1.2E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0347 f24da80d2e350b6577ae5168f59f3b11 375 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 96 110 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Spica_0347 f24da80d2e350b6577ae5168f59f3b11 375 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 252 264 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Spica_0347 f24da80d2e350b6577ae5168f59f3b11 375 SUPERFAMILY SSF48576 45 352 2.02E-56 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_0347 f24da80d2e350b6577ae5168f59f3b11 375 Pfam PF00348 Polyprenyl synthetase 46 308 6.8E-47 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Spica_0347 f24da80d2e350b6577ae5168f59f3b11 375 Gene3D G3DSA:1.10.600.10 39 373 6.6E-64 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 Pfam PF00288 GHMP kinases N terminal domain 150 215 2.7E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PIRSF PIRSF000530 27 413 2.7E-42 T 13-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 Gene3D G3DSA:3.30.230.10 55 234 2.2E-84 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00473 Galactokinase signature 60 78 4.1E-8 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00473 Galactokinase signature 303 317 4.1E-8 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00473 Galactokinase signature 144 162 4.1E-8 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 SUPERFAMILY SSF55060 240 436 1.58E-23 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 Gene3D G3DSA:3.30.70.890 235 413 2.2E-84 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 SUPERFAMILY SSF54211 41 236 9.11E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 Pfam PF10509 Galactokinase galactose-binding signature 45 91 8.0E-13 T 13-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00959 Mevalonate kinase family signature 195 214 2.0E-21 T 13-10-2018 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00959 Mevalonate kinase family signature 151 173 2.0E-21 T 13-10-2018 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00959 Mevalonate kinase family signature 58 82 2.0E-21 T 13-10-2018 Spica_0453 39077c048b2ff7f9f7763c4aa84fc1f9 441 PRINTS PR00959 Mevalonate kinase family signature 388 405 2.0E-21 T 13-10-2018 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Gene3D G3DSA:3.40.50.720 337 475 1.2E-73 T 13-10-2018 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 241 496 1.0E-62 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 245 325 2.9E-20 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Gene3D G3DSA:3.40.50.10860 243 497 1.2E-73 T 13-10-2018 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 SUPERFAMILY SSF51735 338 497 1.6E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Gene3D G3DSA:3.20.20.70 1 239 2.5E-45 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 SUPERFAMILY SSF51569 3 233 7.69E-37 T 13-10-2018 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 240 497 26.56 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 355 427 6.9E-6 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 Pfam PF01487 Type I 3-dehydroquinase 5 231 3.2E-47 T 13-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Spica_2328 cf3d7afb17f4735563a0fd78b0d5ddc4 498 SUPERFAMILY SSF53223 232 337 4.2E-26 T 13-10-2018 Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 SUPERFAMILY SSF46785 9 84 5.64E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 Gene3D G3DSA:1.20.120.530 81 215 4.4E-14 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 SMART SM00345 17 75 3.2E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.6E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.6E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 SUPERFAMILY SSF48008 82 212 7.32E-18 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 8.3E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 Pfam PF07729 FCD domain 89 208 9.2E-15 T 13-10-2018 IPR011711 GntR, C-terminal Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 Gene3D G3DSA:1.10.10.10 10 76 3.8E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0606 90e2772594c88fbf72ec0e301cc1ac39 243 SMART SM00895 85 209 0.0031 T 13-10-2018 IPR011711 GntR, C-terminal Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 SUPERFAMILY SSF52172 5 195 4.98E-34 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 SMART SM00448 6 117 1.2E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 SUPERFAMILY SSF46689 365 478 1.03E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Gene3D G3DSA:1.10.8.60 322 386 1.3E-17 T 13-10-2018 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 SMART SM00382 171 314 2.5E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 237 252 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Gene3D G3DSA:1.10.10.60 418 479 1.1E-15 T 13-10-2018 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 364 373 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Pfam PF02954 Bacterial regulatory protein, Fis family 436 476 9.7E-15 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Gene3D G3DSA:3.40.50.2300 4 139 3.1E-29 T 13-10-2018 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Pfam PF00072 Response regulator receiver domain 8 118 6.5E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 SUPERFAMILY SSF52540 149 381 8.79E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Pfam PF00158 Sigma-54 interaction domain 150 316 1.3E-66 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 Gene3D G3DSA:3.40.50.300 140 321 6.5E-62 T 13-10-2018 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 459 479 6.1E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_0968 faeeaddacd25c69aaf1e25afdf7b1479 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 442 459 6.1E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 Gene3D G3DSA:3.30.470.20 86 222 8.4E-99 T 13-10-2018 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 233 7.9E-77 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 ProSitePatterns PS01058 SAICAR synthetase signature 2. 174 182 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 ProSitePatterns PS01057 SAICAR synthetase signature 1. 87 101 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 Pfam PF01259 SAICAR synthetase 8 231 1.8E-69 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 Gene3D G3DSA:3.30.200.20 8 233 8.4E-99 T 13-10-2018 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 SUPERFAMILY SSF56104 4 234 1.24E-83 T 13-10-2018 Spica_2413 b5afe2ea748ad35d4ab944d51cb0b08d 236 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 5 236 33.125 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 SUPERFAMILY SSF56059 140 336 5.48E-59 T 13-10-2018 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 45 388 2.8E-118 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 Gene3D G3DSA:3.40.50.20 35 144 3.2E-33 T 13-10-2018 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 Gene3D G3DSA:3.30.470.20 219 399 2.4E-67 T 13-10-2018 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 Pfam PF02222 ATP-grasp domain 149 315 3.1E-57 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type Spica_2463 bf0661606224d178703f8e79ac5c0375 399 SUPERFAMILY SSF51246 340 395 1.49E-15 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 SUPERFAMILY SSF52440 42 136 1.44E-24 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_2463 bf0661606224d178703f8e79ac5c0375 399 Gene3D G3DSA:3.30.1490.20 145 218 1.9E-28 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_2463 bf0661606224d178703f8e79ac5c0375 399 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 44 387 41.169 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Spica_1385 e0102aa3b7821ed368faeabeab12ea42 436 Pfam PF01098 Cell cycle protein 223 431 7.5E-54 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1385 e0102aa3b7821ed368faeabeab12ea42 436 Pfam PF01098 Cell cycle protein 14 204 6.4E-33 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1385 e0102aa3b7821ed368faeabeab12ea42 436 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 10 433 7.5E-117 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1385 e0102aa3b7821ed368faeabeab12ea42 436 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 4 436 25.388 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1385 e0102aa3b7821ed368faeabeab12ea42 436 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 391 415 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2665 aefb0ce7af4a1b1fc3382057182cd5f0 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 47 4.3E-10 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Spica_2665 aefb0ce7af4a1b1fc3382057182cd5f0 77 SMART SM00966 6 51 1.5E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Spica_2665 aefb0ce7af4a1b1fc3382057182cd5f0 77 Gene3D G3DSA:2.10.260.10 1 77 1.2E-23 T 13-10-2018 Spica_2665 aefb0ce7af4a1b1fc3382057182cd5f0 77 SUPERFAMILY SSF89447 1 68 1.92E-15 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Spica_2040 060a09ec25d18845f61f9fd5d3838b67 408 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3 83 1.0E-33 T 13-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2040 060a09ec25d18845f61f9fd5d3838b67 408 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 86 327 1.9E-109 T 13-10-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2040 060a09ec25d18845f61f9fd5d3838b67 408 Pfam PF07055 Enoyl reductase FAD binding domain 340 403 8.4E-26 T 13-10-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2040 060a09ec25d18845f61f9fd5d3838b67 408 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 408 51.244 T 13-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2040 060a09ec25d18845f61f9fd5d3838b67 408 Gene3D G3DSA:3.40.50.720 1 408 7.4E-161 T 13-10-2018 Spica_1428 44c07f8025cf58975d5b22b033f2d6b8 154 SUPERFAMILY SSF50249 4 154 1.06E-45 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1428 44c07f8025cf58975d5b22b033f2d6b8 154 Gene3D G3DSA:2.40.50.140 1 121 3.6E-41 T 13-10-2018 Spica_1428 44c07f8025cf58975d5b22b033f2d6b8 154 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 154 1.1E-42 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Spica_1428 44c07f8025cf58975d5b22b033f2d6b8 154 Hamap MF_00984 Single-stranded DNA-binding protein. 4 109 32.449 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Spica_1428 44c07f8025cf58975d5b22b033f2d6b8 154 Pfam PF00436 Single-strand binding protein family 4 105 2.1E-32 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Spica_0908 8a53328147f803637ce3d618a895f5a1 207 Pfam PF01569 PAP2 superfamily 73 188 8.9E-20 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_0908 8a53328147f803637ce3d618a895f5a1 207 SMART SM00014 69 184 1.5E-13 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_0908 8a53328147f803637ce3d618a895f5a1 207 SUPERFAMILY SSF48317 12 197 5.23E-31 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily Spica_0908 8a53328147f803637ce3d618a895f5a1 207 Gene3D G3DSA:1.20.144.10 104 205 1.7E-20 T 13-10-2018 Spica_1310 e13ba2ced3c86510271234747c4b28e2 187 PIRSF PIRSF016661 1 186 7.8E-47 T 13-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Spica_1310 e13ba2ced3c86510271234747c4b28e2 187 Gene3D G3DSA:1.10.1760.20 1 185 6.1E-55 T 13-10-2018 Spica_1310 e13ba2ced3c86510271234747c4b28e2 187 Pfam PF02632 BioY family 33 178 1.1E-38 T 13-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 Spica_0595 1d7c3aab8c259db3c0f6846e172e429a 267 SUPERFAMILY SSF102705 25 264 2.88E-31 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Spica_0595 1d7c3aab8c259db3c0f6846e172e429a 267 Gene3D G3DSA:3.40.1390.30 25 242 3.8E-16 T 13-10-2018 Spica_0595 1d7c3aab8c259db3c0f6846e172e429a 267 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 21 252 3.5E-21 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spica_0595 1d7c3aab8c259db3c0f6846e172e429a 267 Gene3D G3DSA:3.40.1390.30 106 230 3.8E-16 T 13-10-2018 Spica_2493 5fd85d5b63190e39587190711ebd90c1 300 Gene3D G3DSA:3.90.1580.10 24 272 2.7E-85 T 13-10-2018 Spica_2493 5fd85d5b63190e39587190711ebd90c1 300 Pfam PF03781 Sulfatase-modifying factor enzyme 1 31 271 5.7E-57 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Spica_2493 5fd85d5b63190e39587190711ebd90c1 300 SUPERFAMILY SSF56436 30 272 2.83E-67 T 13-10-2018 IPR016187 C-type lectin fold Spica_0217 12c61fa2f6f294f4c661c010171c66b5 92 SUPERFAMILY SSF52833 7 84 3.35E-11 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0217 12c61fa2f6f294f4c661c010171c66b5 92 Gene3D G3DSA:3.40.30.10 3 84 3.3E-13 T 13-10-2018 Spica_0217 12c61fa2f6f294f4c661c010171c66b5 92 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 3 83 3.9E-9 T 13-10-2018 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 Gene3D G3DSA:3.40.50.720 4 98 1.8E-21 T 13-10-2018 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 SUPERFAMILY SSF53623 105 374 9.26E-27 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 Gene3D G3DSA:3.90.190.20 381 515 4.3E-34 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 SUPERFAMILY SSF53244 376 516 5.49E-28 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 172 514 3.5E-77 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 Pfam PF08245 Mur ligase middle domain 113 353 2.3E-15 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Spica_0978 65ffc6461e075cdb5637128b599ba84f 517 SUPERFAMILY SSF51984 4 97 2.88E-14 T 13-10-2018 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SMART SM00028 174 207 0.68 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SMART SM00028 260 293 0.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SMART SM00028 328 361 0.0021 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SMART SM00028 294 327 0.011 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 Gene3D G3DSA:1.25.40.10 211 373 1.5E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 Pfam PF14559 Tetratricopeptide repeat 304 371 5.3E-10 T 13-10-2018 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SUPERFAMILY SSF48452 87 293 9.62E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 SUPERFAMILY SSF48452 250 371 1.39E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 Gene3D G3DSA:1.25.40.10 56 210 3.7E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0674 8824c06af5e2b86fa0f5b5eedeafd545 373 Pfam PF13432 Tetratricopeptide repeat 231 290 9.2E-4 T 13-10-2018 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 Pfam PF01264 Chorismate synthase 10 342 7.7E-140 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 TIGRFAM TIGR00033 aroC: chorismate synthase 10 346 2.4E-131 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 SUPERFAMILY SSF103263 4 346 4.84E-136 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 Hamap MF_00300 Chorismate synthase [aroC]. 10 351 36.118 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 Gene3D G3DSA:3.60.150.10 1 351 1.9E-151 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_2308 24f1e9fc61e076c4f067210b7f056715 351 PIRSF PIRSF001456 3 350 2.1E-138 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 Gene3D G3DSA:1.10.155.10 4 79 1.0E-19 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 SUPERFAMILY SSF53335 81 279 4.17E-52 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PIRSF PIRSF000410 3 282 4.2E-95 T 13-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 149 165 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 221 235 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 240 263 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 34 47 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 74 86 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 PRINTS PR00996 Glutamate methyltransferase family signature 114 134 8.1E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 SMART SM00138 12 281 4.7E-89 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 Gene3D G3DSA:3.40.50.150 80 281 1.7E-61 T 13-10-2018 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 81 271 1.9E-59 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 SUPERFAMILY SSF47757 5 80 2.22E-17 T 13-10-2018 Spica_0799 0bbb6dac689f9c016f6358fe029a895d 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 14 64 5.5E-15 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 Pfam PF07568 Histidine kinase 334 404 3.0E-17 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 Gene3D G3DSA:3.30.565.10 392 538 5.5E-21 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 SUPERFAMILY SSF55874 427 531 4.71E-14 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 Pfam PF05228 CHASE4 domain 53 196 8.0E-28 T 13-10-2018 IPR007892 CHASE4 Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 Gene3D G3DSA:3.30.450.20 294 384 1.2E-5 T 13-10-2018 Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 SMART SM00387 434 533 6.0E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 6.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 490 6.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 6.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_1846 8707a544893ec6fba2ca6adbc2ea6bb2 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 531 1.3E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 SUPERFAMILY SSF51735 145 311 9.58E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 Pfam PF00107 Zinc-binding dehydrogenase 182 310 5.3E-20 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 Gene3D G3DSA:3.90.180.10 22 336 6.1E-81 T 13-10-2018 Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 SUPERFAMILY SSF50129 4 346 7.81E-42 T 13-10-2018 IPR011032 GroES-like superfamily Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 140 1.2E-25 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 Gene3D G3DSA:3.40.50.720 167 293 6.1E-81 T 13-10-2018 Spica_2347 14d1c208825dd836d1b69ee8e85e4012 351 SMART SM00829 12 346 7.1E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spica_0552 23271000b0370d3432d818c53ed7921f 576 SUPERFAMILY SSF55874 454 572 3.8E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0552 23271000b0370d3432d818c53ed7921f 576 Pfam PF02743 Cache domain 45 270 1.8E-13 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_0552 23271000b0370d3432d818c53ed7921f 576 Gene3D G3DSA:3.30.450.20 36 177 3.3E-15 T 13-10-2018 Spica_0552 23271000b0370d3432d818c53ed7921f 576 Pfam PF07568 Histidine kinase 385 455 1.2E-15 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0552 23271000b0370d3432d818c53ed7921f 576 Gene3D G3DSA:3.30.450.20 350 434 6.8E-8 T 13-10-2018 Spica_0552 23271000b0370d3432d818c53ed7921f 576 Gene3D G3DSA:3.30.565.10 440 575 3.1E-22 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0552 23271000b0370d3432d818c53ed7921f 576 SUPERFAMILY SSF103190 69 183 3.14E-5 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_0552 23271000b0370d3432d818c53ed7921f 576 SMART SM00911 385 461 0.0012 T 13-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 Spica_0552 23271000b0370d3432d818c53ed7921f 576 SMART SM00387 478 575 1.3E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2453 1befe0088a49a54b5d02c3d0233834a9 306 SUPERFAMILY SSF161098 60 291 2.88E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2453 1befe0088a49a54b5d02c3d0233834a9 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 300 4.0E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2453 1befe0088a49a54b5d02c3d0233834a9 306 Gene3D G3DSA:1.10.3720.10 56 306 6.0E-63 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2772 6c6feb9a56e42708ef47069c73400c79 184 Gene3D G3DSA:2.60.40.790 6 179 2.3E-14 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_2772 6c6feb9a56e42708ef47069c73400c79 184 Pfam PF00011 Hsp20/alpha crystallin family 83 179 4.6E-9 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Spica_2772 6c6feb9a56e42708ef47069c73400c79 184 SUPERFAMILY SSF49764 62 177 1.74E-14 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_0018 e990c28e04f38a4c6caef9d169162ef3 257 Gene3D G3DSA:3.60.15.10 12 243 1.0E-35 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0018 e990c28e04f38a4c6caef9d169162ef3 257 SMART SM00849 35 226 2.8E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0018 e990c28e04f38a4c6caef9d169162ef3 257 Pfam PF00753 Metallo-beta-lactamase superfamily 32 226 4.6E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0018 e990c28e04f38a4c6caef9d169162ef3 257 SUPERFAMILY SSF56281 10 244 1.57E-29 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1517 660afa1c3d6bf4cc6c7e6c8899cba2a9 168 SMART SM00260 6 143 2.6E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_1517 660afa1c3d6bf4cc6c7e6c8899cba2a9 168 SUPERFAMILY SSF50341 6 146 2.22E-36 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_1517 660afa1c3d6bf4cc6c7e6c8899cba2a9 168 Gene3D G3DSA:2.40.50.180 25 138 4.2E-40 T 13-10-2018 Spica_1517 660afa1c3d6bf4cc6c7e6c8899cba2a9 168 Gene3D G3DSA:2.30.30.40 8 137 4.2E-40 T 13-10-2018 Spica_1517 660afa1c3d6bf4cc6c7e6c8899cba2a9 168 Pfam PF01584 CheW-like domain 6 144 3.7E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 200 210 2.0E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 2.0E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 2.0E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 2.0E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 Gene3D G3DSA:3.40.50.620 6 330 7.7E-115 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 Pfam PF00579 tRNA synthetases class I (W and Y) 6 285 5.2E-56 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 SUPERFAMILY SSF52374 6 330 5.36E-85 T 13-10-2018 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 331 35.63 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 330 4.3E-88 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 Gene3D G3DSA:1.10.240.10 195 298 7.7E-115 T 13-10-2018 Spica_0495 be3729f9c2c5bc4c07e8b3bbd37f1707 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 Gene3D G3DSA:3.40.50.300 6 223 4.4E-67 T 13-10-2018 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 SMART SM00382 30 213 1.1E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 370 3.1E-113 T 13-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 SUPERFAMILY SSF50331 238 373 6.23E-14 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 Pfam PF00005 ABC transporter 21 163 3.6E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 SUPERFAMILY SSF52540 6 243 4.34E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 Gene3D G3DSA:2.40.50.940 224 296 4.8E-9 T 13-10-2018 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 Pfam PF08402 TOBE domain 291 372 2.2E-9 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2140 555c2229acbbc91739c5bcc06e2583d0 379 Gene3D G3DSA:2.40.50.140 297 320 4.8E-9 T 13-10-2018 Spica_0557 2f51b035f9a3615287607a7845a6be56 295 Pfam PF06426 Serine acetyltransferase, N-terminal 102 152 1.4E-4 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Spica_0557 2f51b035f9a3615287607a7845a6be56 295 Gene3D G3DSA:1.10.3130.10 27 183 7.0E-47 T 13-10-2018 Spica_0557 2f51b035f9a3615287607a7845a6be56 295 Gene3D G3DSA:2.160.10.10 184 295 6.1E-30 T 13-10-2018 Spica_0557 2f51b035f9a3615287607a7845a6be56 295 SUPERFAMILY SSF51161 109 282 1.01E-43 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_0557 2f51b035f9a3615287607a7845a6be56 295 PIRSF PIRSF000441 116 291 1.2E-51 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Spica_0557 2f51b035f9a3615287607a7845a6be56 295 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 238 273 0.0011 T 13-10-2018 IPR001451 Hexapeptide repeat Spica_0557 2f51b035f9a3615287607a7845a6be56 295 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 188 224 2.5E-5 T 13-10-2018 IPR001451 Hexapeptide repeat Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 PIRSF PIRSF002155 1 223 7.6E-76 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 Pfam PF00687 Ribosomal protein L1p/L10e family 30 216 2.5E-51 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 SUPERFAMILY SSF56808 5 221 2.49E-75 T 13-10-2018 IPR023674 Ribosomal protein L1-like Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 ProSitePatterns PS01199 Ribosomal protein L1 signature. 117 135 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 Gene3D G3DSA:3.30.190.20 24 218 8.0E-78 T 13-10-2018 Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 223 1.6E-95 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 225 37.329 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Spica_0376 b781d3be79602ce31b9fb06753c5ea86 226 Gene3D G3DSA:3.40.50.790 64 155 8.0E-78 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 SUPERFAMILY SSF51182 56 186 1.02E-26 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 Gene3D G3DSA:1.10.260.40 2 82 6.0E-21 T 13-10-2018 Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 SMART SM00530 8 63 2.0E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 Pfam PF01381 Helix-turn-helix 9 63 5.7E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 Pfam PF07883 Cupin domain 113 181 1.6E-16 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 SUPERFAMILY SSF47413 3 67 6.48E-19 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0938 2320e222ee78c517fd30fb51a9ea90ca 193 Gene3D G3DSA:2.60.120.10 100 191 9.6E-19 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 299 6.4E-15 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 318 1.2E-27 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 Gene3D G3DSA:3.40.50.300 2 323 2.0E-96 T 13-10-2018 Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 SUPERFAMILY SSF52540 4 253 7.87E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 Pfam PF00005 ABC transporter 25 181 1.1E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2033 f2f6d93aa6e98f5a2a7fc04ce5d05228 324 SMART SM00382 33 231 3.0E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 SUPERFAMILY SSF52540 379 625 1.25E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 Pfam PF00664 ABC transporter transmembrane region 63 342 4.3E-51 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 Pfam PF00005 ABC transporter 406 554 2.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 Gene3D G3DSA:3.40.50.300 385 630 5.6E-85 T 13-10-2018 Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 SUPERFAMILY SSF90123 45 372 5.62E-84 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 SMART SM00382 414 600 3.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0302 ce6418bd8af237c6465a0b38f1228239 634 Gene3D G3DSA:1.20.1560.10 29 374 6.3E-102 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Gene3D G3DSA:2.30.30.300 174 218 2.2E-94 T 13-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 6 527 4.1E-165 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Gene3D G3DSA:1.10.10.350 434 526 2.8E-18 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Gene3D G3DSA:1.10.10.770 325 433 1.5E-29 T 13-10-2018 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Gene3D G3DSA:1.10.10.860 277 324 5.5E-22 T 13-10-2018 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 SUPERFAMILY SSF52374 7 325 2.2E-58 T 13-10-2018 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 6 527 33.586 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Pfam PF01921 tRNA synthetases class I (K) 7 369 4.5E-128 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 Gene3D G3DSA:3.40.50.620 8 276 2.2E-94 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 43 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2517 7804c3777349bc2a6c723b8ff57645ca 527 SUPERFAMILY SSF48163 329 525 7.85E-33 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 SUPERFAMILY SSF52540 168 411 2.33E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Pfam PF06480 FtsH Extracellular 26 114 6.8E-9 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Gene3D G3DSA:1.20.58.760 422 622 1.2E-70 T 13-10-2018 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Gene3D G3DSA:1.10.8.60 342 419 3.8E-28 T 13-10-2018 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 339 7.4E-43 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 SUPERFAMILY SSF140990 422 611 7.06E-65 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 122 611 2.0E-224 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Gene3D G3DSA:2.40.50.920 42 118 5.8E-8 T 13-10-2018 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 22 616 35.479 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 ProSitePatterns PS00674 AAA-protein family signature. 311 329 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Pfam PF01434 Peptidase family M41 402 610 2.6E-74 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 Gene3D G3DSA:3.40.50.300 161 340 8.9E-67 T 13-10-2018 Spica_0794 f9b41260aaeef6b41a8f78e7c37906f9 629 SMART SM00382 204 343 1.6E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 607 39.629 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Pfam PF01380 SIS domain 289 416 8.8E-29 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Pfam PF01380 SIS domain 460 584 4.5E-25 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 SUPERFAMILY SSF56235 2 231 2.32E-71 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Gene3D G3DSA:3.40.50.10490 445 592 6.5E-147 T 13-10-2018 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Gene3D G3DSA:3.40.50.10490 246 606 6.5E-147 T 13-10-2018 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Gene3D G3DSA:3.60.20.10 2 239 9.0E-78 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 607 8.6E-245 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 SUPERFAMILY SSF53697 243 607 1.29E-105 T 13-10-2018 Spica_2048 d2eb54338b5c85bb37883586ffe4d816 607 Pfam PF13522 Glutamine amidotransferase domain 63 191 1.8E-20 T 13-10-2018 Spica_1756 0b47a46b79bda2982a3e873699a17f27 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 6.3E-15 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spica_1756 0b47a46b79bda2982a3e873699a17f27 130 Gene3D G3DSA:3.10.180.10 1 129 2.0E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spica_1756 0b47a46b79bda2982a3e873699a17f27 130 SUPERFAMILY SSF54593 1 128 8.19E-26 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spica_1780 0b47a46b79bda2982a3e873699a17f27 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 6.3E-15 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Spica_1780 0b47a46b79bda2982a3e873699a17f27 130 Gene3D G3DSA:3.10.180.10 1 129 2.0E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spica_1780 0b47a46b79bda2982a3e873699a17f27 130 SUPERFAMILY SSF54593 1 128 8.19E-26 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Spica_0135 55018f9ab87f481bcbc45ec282067597 505 Gene3D G3DSA:1.10.1060.10 49 181 3.7E-41 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 SUPERFAMILY SSF46548 40 193 8.89E-36 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 183 491 2.2E-33 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 SUPERFAMILY SSF51971 181 436 9.42E-65 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 Gene3D G3DSA:3.40.50.720 182 291 6.5E-13 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 325 343 4.0E-18 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 428 444 4.0E-18 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 204 4.0E-18 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 456 478 4.0E-18 T 13-10-2018 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 58 170 3.5E-41 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 321 345 1.1E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 184 206 1.1E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 466 484 1.1E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 55 501 1.6E-195 T 13-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 Spica_0135 55018f9ab87f481bcbc45ec282067597 505 Gene3D G3DSA:3.50.50.60 292 437 4.7E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0135 55018f9ab87f481bcbc45ec282067597 505 SUPERFAMILY SSF51971 421 504 1.12E-8 T 13-10-2018 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 470 499 2.4E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 393 2.4E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 468 2.4E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 402 550 4.2E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 Gene3D G3DSA:1.10.287.950 298 585 5.2E-65 T 13-10-2018 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 SUPERFAMILY SSF58104 328 584 7.94E-56 T 13-10-2018 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 SMART SM00283 350 583 9.5E-56 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1882 96b3e1195915b453b241fe2791f0560c 664 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 182 3.5E-16 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Gene3D G3DSA:3.40.50.300 320 497 2.9E-65 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 495 3.7E-22 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 757 765 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PIRSF PIRSF001174 6 605 6.3E-215 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PIRSF PIRSF001174 633 855 2.6E-87 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Gene3D G3DSA:2.30.130.40 9 123 7.3E-24 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 17 207 1.1E-38 T 13-10-2018 IPR003111 Lon, substrate-binding domain Spica_1947 6fb7110515c39bf6580f608c3a848612 855 SUPERFAMILY SSF88697 22 206 5.22E-34 T 13-10-2018 IPR015947 PUA-like superfamily Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 362 381 4.6E-51 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 807 825 4.6E-51 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 754 773 4.6E-51 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 675 691 4.6E-51 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 784 803 4.6E-51 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 650 852 6.4E-82 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Gene3D G3DSA:1.20.58.1480 126 249 4.6E-36 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Gene3D G3DSA:3.30.230.10 666 852 5.5E-75 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1947 6fb7110515c39bf6580f608c3a848612 855 SMART SM00464 16 207 1.4E-55 T 13-10-2018 IPR003111 Lon, substrate-binding domain Spica_1947 6fb7110515c39bf6580f608c3a848612 855 SMART SM00382 354 502 4.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Gene3D G3DSA:1.10.8.60 498 590 6.8E-23 T 13-10-2018 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 TIGRFAM TIGR00763 lon: endopeptidase La 20 851 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spica_1947 6fb7110515c39bf6580f608c3a848612 855 SUPERFAMILY SSF54211 675 851 2.66E-50 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1947 6fb7110515c39bf6580f608c3a848612 855 SUPERFAMILY SSF52540 319 569 3.84E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1947 6fb7110515c39bf6580f608c3a848612 855 Hamap MF_01973 Lon protease [lon]. 17 853 64.456 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 SUPERFAMILY SSF53067 332 585 3.7E-34 T 13-10-2018 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 332 584 9.1E-43 T 13-10-2018 IPR008275 CoA enzyme activase Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Gene3D G3DSA:3.30.420.40 430 569 9.0E-77 T 13-10-2018 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Gene3D G3DSA:3.30.420.40 93 236 3.2E-53 T 13-10-2018 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 SUPERFAMILY SSF53067 7 254 1.05E-18 T 13-10-2018 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 795 1018 4.8E-41 T 13-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 77 252 1.7E-19 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 333 584 2.3E-37 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Gene3D G3DSA:3.30.420.40 333 584 9.0E-77 T 13-10-2018 Spica_2467 79e81c18ae0610776206d6d8313dca78 1536 Gene3D G3DSA:3.30.420.40 8 250 3.2E-53 T 13-10-2018 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Pfam PF06071 Protein of unknown function (DUF933) 285 368 2.1E-41 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 PIRSF PIRSF006641 1 369 1.2E-155 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 SUPERFAMILY SSF52540 3 306 8.11E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Pfam PF01926 50S ribosome-binding GTPase 5 128 5.9E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 369 7.5E-144 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 369 43.026 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Gene3D G3DSA:1.10.150.300 113 204 1.1E-149 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.5E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.5E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.5E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.5E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 SUPERFAMILY SSF81271 285 366 1.31E-36 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Gene3D G3DSA:3.40.50.300 3 284 1.1E-149 T 13-10-2018 Spica_2390 4e4eb6c1424c0b184f4a00016963549c 369 Gene3D G3DSA:3.10.20.30 48 367 1.1E-149 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 Gene3D G3DSA:1.10.275.10 17 133 1.5E-18 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 Pfam PF00206 Lyase 44 331 3.1E-53 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 SUPERFAMILY SSF48557 12 416 3.3E-76 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 ProSitePatterns PS00163 Fumarate lyases signature. 308 317 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 PRINTS PR00149 Fumarate lyase superfamily signature 174 192 3.7E-16 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 3.7E-16 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 PRINTS PR00149 Fumarate lyase superfamily signature 308 324 3.7E-16 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 PRINTS PR00149 Fumarate lyase superfamily signature 129 147 3.7E-16 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1874 fe1530739152d3e333ee9dde32f31b54 481 Gene3D G3DSA:1.20.200.10 134 397 4.7E-71 T 13-10-2018 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 3.6E-38 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 SUPERFAMILY SSF52833 5 106 3.0E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 Pfam PF00085 Thioredoxin 6 103 1.3E-30 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 PIRSF PIRSF000077 1 107 3.2E-39 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 Gene3D G3DSA:3.40.30.10 1 106 2.4E-34 T 13-10-2018 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 PRINTS PR00421 Thioredoxin family signature 31 40 2.9E-7 T 13-10-2018 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 PRINTS PR00421 Thioredoxin family signature 23 31 2.9E-7 T 13-10-2018 Spica_2053 f03424480cb1cc177a08d8c3a81f7eb0 107 PRINTS PR00421 Thioredoxin family signature 71 82 2.9E-7 T 13-10-2018 Spica_0451 248d61ae5bff6e980be6ea5054f1948a 164 Pfam PF05130 FlgN protein 26 157 7.1E-8 T 13-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 Spica_0451 248d61ae5bff6e980be6ea5054f1948a 164 SUPERFAMILY SSF140566 24 139 5.1E-7 T 13-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 SUPERFAMILY SSF53067 1 312 2.1E-37 T 13-10-2018 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 Gene3D G3DSA:3.30.420.40 128 298 2.4E-110 T 13-10-2018 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 153 174 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 271 280 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 130 142 4.0E-42 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 336 57.741 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 4.0E-104 T 13-10-2018 IPR017861 Kae1/TsaD family Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 Pfam PF00814 Glycoprotease family 24 311 1.0E-87 T 13-10-2018 IPR000905 Gcp-like domain Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 2.3E-118 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Spica_0851 169b21b826d5e720e02abcbf6bc9cc1a 342 Gene3D G3DSA:3.30.420.40 3 319 2.4E-110 T 13-10-2018 Spica_0083 4d466d3da607a403237bc9f431c89bc9 242 Pfam PF00072 Response regulator receiver domain 9 120 3.8E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0083 4d466d3da607a403237bc9f431c89bc9 242 SUPERFAMILY SSF52172 6 125 8.4E-40 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0083 4d466d3da607a403237bc9f431c89bc9 242 SMART SM00448 7 120 4.5E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0083 4d466d3da607a403237bc9f431c89bc9 242 Gene3D G3DSA:3.40.50.12740 6 198 5.4E-43 T 13-10-2018 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 229 5.2E-38 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 SUPERFAMILY SSF55120 65 229 6.72E-36 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 Gene3D G3DSA:3.10.290.10 7 58 1.9E-5 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 Gene3D G3DSA:3.30.70.1560 133 214 3.7E-48 T 13-10-2018 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 Pfam PF01479 S4 domain 8 41 9.9E-6 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 Pfam PF00849 RNA pseudouridylate synthase 66 197 4.1E-15 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 SUPERFAMILY SSF55174 4 50 4.91E-5 T 13-10-2018 Spica_2744 309a4ccd9747ea28a927c0fc2d093ac0 242 Gene3D G3DSA:3.30.70.580 66 232 3.7E-48 T 13-10-2018 Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 SUPERFAMILY SSF88946 9 105 5.76E-23 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 Gene3D G3DSA:1.10.10.10 126 186 6.9E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 Pfam PF04542 Sigma-70 region 2 27 93 1.4E-14 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 Pfam PF08281 Sigma-70, region 4 129 180 7.7E-14 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 SUPERFAMILY SSF88659 117 184 5.05E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 Gene3D G3DSA:1.10.1740.10 3 118 8.7E-30 T 13-10-2018 Spica_0333 f1b49ed2485ffffa125660bfb549b3e3 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 183 4.9E-27 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_1370 cff8bed9ea41320951e25321b90e8da8 384 SMART SM00028 37 70 40.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1370 cff8bed9ea41320951e25321b90e8da8 384 SMART SM00028 71 104 5.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1370 cff8bed9ea41320951e25321b90e8da8 384 SUPERFAMILY SSF48452 7 125 1.55E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1370 cff8bed9ea41320951e25321b90e8da8 384 Gene3D G3DSA:1.25.40.10 2 119 2.4E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1370 cff8bed9ea41320951e25321b90e8da8 384 Pfam PF13176 Tetratricopeptide repeat 73 101 2.6E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1271 011313810126165ec6be2debdfee998b 389 SUPERFAMILY SSF81301 36 162 1.96E-36 T 13-10-2018 Spica_1271 011313810126165ec6be2debdfee998b 389 SUPERFAMILY SSF81891 163 278 2.88E-21 T 13-10-2018 Spica_1271 011313810126165ec6be2debdfee998b 389 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 193 251 5.0E-10 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Spica_1271 011313810126165ec6be2debdfee998b 389 Gene3D G3DSA:1.10.3090.10 164 357 1.2E-24 T 13-10-2018 Spica_1271 011313810126165ec6be2debdfee998b 389 Pfam PF01743 Poly A polymerase head domain 51 165 3.9E-34 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Spica_1271 011313810126165ec6be2debdfee998b 389 Gene3D G3DSA:3.30.460.10 16 161 1.3E-49 T 13-10-2018 Spica_1271 011313810126165ec6be2debdfee998b 389 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 19 327 4.3E-99 T 13-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 Spica_0482 9c0bbc030883f1c25b63fc5cf2d170c5 397 SMART SM00471 156 292 5.2E-5 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0482 9c0bbc030883f1c25b63fc5cf2d170c5 397 Pfam PF13487 HD domain 213 273 1.2E-15 T 13-10-2018 Spica_0482 9c0bbc030883f1c25b63fc5cf2d170c5 397 Gene3D G3DSA:1.10.3210.10 2 324 5.2E-63 T 13-10-2018 Spica_0482 9c0bbc030883f1c25b63fc5cf2d170c5 397 SUPERFAMILY SSF109604 164 322 2.86E-27 T 13-10-2018 Spica_0169 1104c64563ce3c457a1516b2dcf18069 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 2.8E-59 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0169 1104c64563ce3c457a1516b2dcf18069 155 Gene3D G3DSA:3.40.50.960 1 153 1.3E-64 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0169 1104c64563ce3c457a1516b2dcf18069 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.441 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0169 1104c64563ce3c457a1516b2dcf18069 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 150 1.7E-60 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_0169 1104c64563ce3c457a1516b2dcf18069 155 SUPERFAMILY SSF52121 3 153 1.44E-63 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Spica_1274 2ac5048eda6759c8d3486c8d91939352 343 SMART SM00363 14 74 5.1E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_1274 2ac5048eda6759c8d3486c8d91939352 343 Gene3D G3DSA:3.10.290.10 1 67 7.1E-10 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_1274 2ac5048eda6759c8d3486c8d91939352 343 Pfam PF00849 RNA pseudouridylate synthase 106 259 4.9E-25 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1274 2ac5048eda6759c8d3486c8d91939352 343 SUPERFAMILY SSF55120 97 314 3.42E-42 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1274 2ac5048eda6759c8d3486c8d91939352 343 Gene3D G3DSA:3.30.2350.10 89 289 9.8E-45 T 13-10-2018 Spica_1451 8257e8d1628864ba056f558108ad9683 282 Gene3D G3DSA:3.30.465.10 11 177 3.1E-31 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1451 8257e8d1628864ba056f558108ad9683 282 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 11 176 4.0E-31 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spica_1451 8257e8d1628864ba056f558108ad9683 282 SUPERFAMILY SSF56176 10 177 3.27E-32 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Spica_2150 247cb43e4375550c906727da10db002e 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 310 1.1E-53 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Pfam PF00750 tRNA synthetases class I (R) 106 453 1.1E-56 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 SUPERFAMILY SSF52374 122 462 2.96E-85 T 13-10-2018 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 96 7.7E-14 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Pfam PF05746 DALR anticodon binding domain 468 586 3.1E-30 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 586 2.0E-157 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Hamap MF_00123 Arginine--tRNA ligase [argS]. 20 586 26.699 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Gene3D G3DSA:3.30.1360.70 2 121 2.8E-20 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 145 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Gene3D G3DSA:3.40.50.620 124 466 4.0E-117 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 SUPERFAMILY SSF47323 462 586 6.15E-31 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 SMART SM00836 468 586 2.5E-39 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 Gene3D G3DSA:1.10.730.10 467 586 7.9E-34 T 13-10-2018 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 SMART SM01016 6 96 1.4E-17 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 313 334 1.4E-19 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 126 141 1.4E-19 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 165 178 1.4E-19 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 141 157 1.4E-19 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Spica_0781 ad57de172f8c9ef8d1bc10cba77bda51 586 SUPERFAMILY SSF55190 2 117 2.35E-19 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 Spica_1397 f2cdf9a397ee531c365ce3e5f455eb2d 312 Gene3D G3DSA:3.60.15.10 54 312 1.6E-39 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1397 f2cdf9a397ee531c365ce3e5f455eb2d 312 Pfam PF12706 Beta-lactamase superfamily domain 73 271 3.1E-20 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1397 f2cdf9a397ee531c365ce3e5f455eb2d 312 SUPERFAMILY SSF56281 1 312 6.02E-40 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2088 f098e989fa61503dc4819a76736831bb 314 SMART SM00861 4 169 2.4E-42 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_2088 f098e989fa61503dc4819a76736831bb 314 SUPERFAMILY SSF52922 175 312 2.09E-29 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2088 f098e989fa61503dc4819a76736831bb 314 Gene3D G3DSA:3.40.50.970 1 179 4.3E-53 T 13-10-2018 Spica_2088 f098e989fa61503dc4819a76736831bb 314 Pfam PF02780 Transketolase, C-terminal domain 180 304 1.3E-23 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Spica_2088 f098e989fa61503dc4819a76736831bb 314 SUPERFAMILY SSF52518 4 171 1.39E-46 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2088 f098e989fa61503dc4819a76736831bb 314 Pfam PF02779 Transketolase, pyrimidine binding domain 5 167 2.9E-30 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_2088 f098e989fa61503dc4819a76736831bb 314 Gene3D G3DSA:3.40.50.920 180 314 2.0E-33 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Gene3D G3DSA:1.10.287.950 409 688 2.3E-41 T 13-10-2018 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Gene3D G3DSA:3.40.50.1780 62 239 1.1E-33 T 13-10-2018 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 79 308 9.5E-29 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_2408 e77c6f89622859e171e33eeb63db7228 695 SUPERFAMILY SSF53920 46 334 1.18E-43 T 13-10-2018 IPR009016 Iron hydrogenase Spica_2408 e77c6f89622859e171e33eeb63db7228 695 SUPERFAMILY SSF54862 7 75 1.95E-14 T 13-10-2018 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 SMART SM00283 445 691 3.6E-19 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 SUPERFAMILY SSF58104 433 686 1.57E-40 T 13-10-2018 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Gene3D G3DSA:3.30.70.20 13 61 1.1E-33 T 13-10-2018 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Pfam PF04060 Putative Fe-S cluster 394 421 5.7E-6 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Pfam PF13187 4Fe-4S dicluster domain 15 60 3.0E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 510 663 4.5E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2408 e77c6f89622859e171e33eeb63db7228 695 Gene3D G3DSA:3.40.950.10 118 265 1.1E-33 T 13-10-2018 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 Pfam PF00218 Indole-3-glycerol phosphate synthase 41 266 1.7E-44 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 SUPERFAMILY SSF51366 370 606 1.15E-31 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 450 603 2.2E-13 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 Gene3D G3DSA:3.20.20.70 370 607 1.2E-34 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 SUPERFAMILY SSF51366 41 266 9.42E-41 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 369 609 23.779 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Spica_0176 57bb5ea3560eeaee9fc1bbd364fddd38 645 Gene3D G3DSA:3.20.20.70 1 271 6.6E-67 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0800 56d8d1ea7891300794351c699d552e56 359 PIRSF PIRSF000876 3 359 7.4E-133 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_0800 56d8d1ea7891300794351c699d552e56 359 Gene3D G3DSA:3.40.50.2300 4 135 2.6E-30 T 13-10-2018 Spica_0800 56d8d1ea7891300794351c699d552e56 359 SUPERFAMILY SSF52172 5 111 1.57E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0800 56d8d1ea7891300794351c699d552e56 359 SUPERFAMILY SSF52738 171 356 7.45E-71 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_0800 56d8d1ea7891300794351c699d552e56 359 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 6 359 39.355 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_0800 56d8d1ea7891300794351c699d552e56 359 Gene3D G3DSA:3.40.50.180 165 359 1.3E-74 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_0800 56d8d1ea7891300794351c699d552e56 359 SMART SM00448 6 122 1.4E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0800 56d8d1ea7891300794351c699d552e56 359 Pfam PF00072 Response regulator receiver domain 8 111 2.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0800 56d8d1ea7891300794351c699d552e56 359 Pfam PF01339 CheB methylesterase 176 353 1.5E-60 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_1609 065d4a8b10efe82da44fec97719eb258 538 SUPERFAMILY SSF56317 227 508 1.7E-44 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1609 065d4a8b10efe82da44fec97719eb258 538 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 70 478 2.1E-97 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Spica_1609 065d4a8b10efe82da44fec97719eb258 538 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 13 515 17.366 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Spica_1609 065d4a8b10efe82da44fec97719eb258 538 Pfam PF00795 Carbon-nitrogen hydrolase 233 502 8.3E-28 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Spica_1609 065d4a8b10efe82da44fec97719eb258 538 Gene3D G3DSA:3.60.110.10 223 506 7.0E-23 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1906 daa688f287250e68a88616247da54d4e 1082 SUPERFAMILY SSF49785 37 103 2.41E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_1906 daa688f287250e68a88616247da54d4e 1082 Gene3D G3DSA:2.70.98.30 724 964 1.0E-9 T 13-10-2018 Spica_1906 daa688f287250e68a88616247da54d4e 1082 Gene3D G3DSA:3.20.110.10 238 511 1.3E-48 T 13-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily Spica_1906 daa688f287250e68a88616247da54d4e 1082 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 642 1073 2.3E-67 T 13-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 Spica_1906 daa688f287250e68a88616247da54d4e 1082 Gene3D G3DSA:1.20.1270.50 514 614 2.8E-26 T 13-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 Spica_1906 daa688f287250e68a88616247da54d4e 1082 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 245 504 4.0E-67 T 13-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 Spica_1906 daa688f287250e68a88616247da54d4e 1082 SUPERFAMILY SSF74650 637 1077 6.75E-75 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_1906 daa688f287250e68a88616247da54d4e 1082 SUPERFAMILY SSF88713 244 509 4.89E-61 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1906 daa688f287250e68a88616247da54d4e 1082 SMART SM00872 511 592 2.1E-30 T 13-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 Spica_1906 daa688f287250e68a88616247da54d4e 1082 SUPERFAMILY SSF88688 510 617 1.31E-25 T 13-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily Spica_1906 daa688f287250e68a88616247da54d4e 1082 Pfam PF09261 Alpha mannosidase middle domain 511 591 2.0E-25 T 13-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 Spica_2561 775759ac08ec29f016d829fe92e98550 597 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 207 218 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Spica_2561 775759ac08ec29f016d829fe92e98550 597 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 25 588 1.5E-188 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Pfam PF00391 PEP-utilising enzyme, mobile domain 175 248 2.5E-24 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Spica_2561 775759ac08ec29f016d829fe92e98550 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 316 335 1.1E-21 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 470 485 1.1E-21 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 523 535 1.1E-21 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 487 502 1.1E-21 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 276 563 2.6E-109 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Gene3D G3DSA:1.10.274.10 43 169 2.3E-75 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Spica_2561 775759ac08ec29f016d829fe92e98550 597 SUPERFAMILY SSF51621 277 572 2.04E-103 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Gene3D G3DSA:3.20.20.60 257 596 5.9E-119 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 SUPERFAMILY SSF52009 148 267 8.76E-36 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Gene3D G3DSA:3.50.30.10 26 256 2.3E-75 T 13-10-2018 Spica_2561 775759ac08ec29f016d829fe92e98550 597 Pfam PF05524 PEP-utilising enzyme, N-terminal 25 149 9.9E-26 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Spica_2561 775759ac08ec29f016d829fe92e98550 597 SUPERFAMILY SSF47831 49 164 4.18E-25 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Spica_2561 775759ac08ec29f016d829fe92e98550 597 PIRSF PIRSF000732 19 597 1.6E-213 T 13-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 258 2.6E-29 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 SMART SM00934 17 282 2.7E-38 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 SUPERFAMILY SSF51366 5 259 2.18E-68 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 7 259 3.6E-70 T 13-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 94 107 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 293 34.633 T 13-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_2552 6f53d1a2c212705490ff5043823a8c8b 334 Gene3D G3DSA:3.20.20.70 3 295 1.2E-93 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2153 9efb84f59d146e5fcb1027d8a215176c 271 Gene3D G3DSA:3.40.50.300 2 234 2.6E-65 T 13-10-2018 Spica_2153 9efb84f59d146e5fcb1027d8a215176c 271 Pfam PF00005 ABC transporter 24 168 2.9E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2153 9efb84f59d146e5fcb1027d8a215176c 271 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2153 9efb84f59d146e5fcb1027d8a215176c 271 SUPERFAMILY SSF52540 6 213 1.71E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2153 9efb84f59d146e5fcb1027d8a215176c 271 SMART SM00382 33 215 3.7E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 SUPERFAMILY SSF53955 121 269 9.42E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Pfam PF01476 LysM domain 350 393 1.6E-8 T 13-10-2018 IPR018392 LysM domain Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Pfam PF01476 LysM domain 417 450 2.1E-7 T 13-10-2018 IPR018392 LysM domain Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 SMART SM00257 416 460 1.5E-8 T 13-10-2018 IPR018392 LysM domain Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 SMART SM00257 349 393 3.6E-11 T 13-10-2018 IPR018392 LysM domain Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Pfam PF01464 Transglycosylase SLT domain 128 234 3.2E-24 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Gene3D G3DSA:3.10.350.10 409 466 1.8E-10 T 13-10-2018 IPR036779 LysM domain superfamily Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Gene3D G3DSA:1.10.530.10 118 266 2.5E-29 T 13-10-2018 Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 SUPERFAMILY SSF54106 416 460 3.14E-8 T 13-10-2018 Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 Gene3D G3DSA:3.10.350.10 348 393 3.9E-11 T 13-10-2018 IPR036779 LysM domain superfamily Spica_1841 d874edbff6790b4d63dbb9c4558b3add 469 SUPERFAMILY SSF54106 348 393 1.83E-7 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.2090.10 177 277 6.8E-303 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.70.1430 40 824 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.70.1320 132 334 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.70.1440 678 875 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Pfam PF00873 AcrB/AcrD/AcrF family 3 1035 1.2E-244 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82693 40 133 3.66E-23 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82866 813 1039 1.57E-50 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:1.20.1640.10 521 1032 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.2090.10 728 816 6.8E-303 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82714 729 814 5.49E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82693 135 332 6.02E-18 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82693 578 672 2.88E-8 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:1.20.1640.10 10 520 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 633 647 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 PRINTS PR00702 Acriflavin resistance protein family signature 474 497 3.2E-42 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 Gene3D G3DSA:3.30.70.1430 575 677 6.8E-303 T 13-10-2018 Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82714 183 274 3.79E-11 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0192 00009d4e6809eb111a57f104f4786079 1067 SUPERFAMILY SSF82866 298 500 2.35E-43 T 13-10-2018 Spica_2323 b22d38f480da97a147d48643fbd23730 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 224 235 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_2323 b22d38f480da97a147d48643fbd23730 572 Pfam PF00501 AMP-binding enzyme 41 474 1.4E-77 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_2323 b22d38f480da97a147d48643fbd23730 572 SUPERFAMILY SSF56801 9 570 5.76E-141 T 13-10-2018 Spica_2323 b22d38f480da97a147d48643fbd23730 572 Gene3D G3DSA:3.30.300.310 470 572 1.5E-29 T 13-10-2018 Spica_2323 b22d38f480da97a147d48643fbd23730 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 483 561 1.1E-23 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Spica_2323 b22d38f480da97a147d48643fbd23730 572 Gene3D G3DSA:3.40.50.12780 3 468 1.0E-149 T 13-10-2018 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.6E-28 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.6E-28 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.6E-28 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.6E-28 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 SMART SM01130 3 298 6.3E-131 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 295 6.3E-99 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 296 61.729 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 SUPERFAMILY SSF51569 1 298 3.87E-100 T 13-10-2018 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 PIRSF PIRSF001365 1 301 5.1E-94 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 Gene3D G3DSA:3.20.20.70 1 299 4.4E-111 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0949 f43f57a1bf60d802f9f7ea6fcbfa8a41 302 Pfam PF00701 Dihydrodipicolinate synthetase family 4 296 1.4E-93 T 13-10-2018 IPR002220 DapA-like GO:0016829 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 SMART SM00534 334 519 1.2E-76 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 Pfam PF01713 Smr domain 744 819 7.9E-16 T 13-10-2018 IPR002625 Smr domain Spica_1164 84fa36719ff616cb973b53c315e852a0 821 PIRSF PIRSF005814 1 819 2.5E-203 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 SUPERFAMILY SSF160443 744 819 1.14E-7 T 13-10-2018 IPR036063 Smr domain superfamily Spica_1164 84fa36719ff616cb973b53c315e852a0 821 SMART SM00463 741 819 8.9E-12 T 13-10-2018 IPR002625 Smr domain Spica_1164 84fa36719ff616cb973b53c315e852a0 821 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 416 432 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 Pfam PF00488 MutS domain V 337 519 6.1E-38 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 818 18.672 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 SUPERFAMILY SSF48334 84 292 3.14E-9 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_1164 84fa36719ff616cb973b53c315e852a0 821 SUPERFAMILY SSF52540 307 521 2.79E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1164 84fa36719ff616cb973b53c315e852a0 821 Gene3D G3DSA:3.30.1370.110 736 820 1.4E-20 T 13-10-2018 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 Gene3D G3DSA:3.40.50.300 300 604 5.1E-81 T 13-10-2018 Spica_1164 84fa36719ff616cb973b53c315e852a0 821 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 819 2.6E-177 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 Pfam PF00365 Phosphofructokinase 12 317 1.1E-103 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PIRSF PIRSF000532 8 367 4.2E-120 T 13-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 Gene3D G3DSA:3.40.50.450 12 340 2.0E-116 T 13-10-2018 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 Gene3D G3DSA:3.40.50.460 159 297 2.0E-116 T 13-10-2018 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 231 243 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 40 53 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 112 128 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 281 303 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 14 33 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 156 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 157 175 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 193 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 195 212 1.4E-69 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 10 366 42.75 T 13-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 Spica_2066 6d2401dd53a0680245904b5a0f626cc8 368 SUPERFAMILY SSF53784 9 358 1.57E-117 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 PIRSF PIRSF002158 6 274 4.6E-96 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 274 1.7E-130 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 SMART SM01383 42 118 2.5E-42 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 SUPERFAMILY SSF50249 3 123 1.89E-46 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.662 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 SMART SM01382 124 251 7.9E-87 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.6E-32 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 249 3.4E-55 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Gene3D G3DSA:2.30.30.30 118 196 3.1E-30 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 SUPERFAMILY SSF50104 126 269 2.71E-59 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Gene3D G3DSA:2.40.50.140 1 114 3.6E-44 T 13-10-2018 Spica_0388 c18658513621121c4e4a1a8dcea9d4df 274 Gene3D G3DSA:4.10.950.10 197 274 5.7E-35 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Gene3D G3DSA:2.70.70.10 174 311 1.1E-47 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 SMART SM00257 127 170 2.0E-5 T 13-10-2018 IPR018392 LysM domain Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 SMART SM00257 77 121 1.0E-14 T 13-10-2018 IPR018392 LysM domain Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Gene3D G3DSA:3.10.350.10 125 173 1.5E-9 T 13-10-2018 IPR036779 LysM domain superfamily Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Gene3D G3DSA:3.10.350.10 73 124 3.7E-15 T 13-10-2018 IPR036779 LysM domain superfamily Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Pfam PF01551 Peptidase family M23 212 306 2.2E-32 T 13-10-2018 IPR016047 Peptidase M23 Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Pfam PF01476 LysM domain 78 121 1.8E-15 T 13-10-2018 IPR018392 LysM domain Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 Pfam PF01476 LysM domain 128 170 9.2E-7 T 13-10-2018 IPR018392 LysM domain Spica_0341 bfc826a369f43b419e0869ff04f1d811 311 SUPERFAMILY SSF51261 78 308 6.8E-56 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_2589 2e53dc5823cd68a2216d094cef168a0d 474 SUPERFAMILY SSF48208 61 403 1.28E-58 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_2589 2e53dc5823cd68a2216d094cef168a0d 474 Gene3D G3DSA:1.50.10.10 53 381 2.5E-50 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_2589 2e53dc5823cd68a2216d094cef168a0d 474 Pfam PF01204 Trehalase 176 339 3.5E-11 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 Gene3D G3DSA:1.20.1050.90 118 296 2.3E-84 T 13-10-2018 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 355 65.746 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 348 1.1E-69 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 ProSitePatterns PS00617 RecF protein signature 1. 115 135 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 ProSitePatterns PS00618 RecF protein signature 2. 297 315 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 Pfam PF02463 RecF/RecN/SMC N terminal domain 8 326 1.7E-12 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 SUPERFAMILY SSF52540 1 322 4.97E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0003 f35d588df36062e7462b4bc4d954ebd9 355 Gene3D G3DSA:3.40.50.300 10 328 2.3E-84 T 13-10-2018 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 28 303 1.0E-52 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 SMART SM01217 608 677 3.5E-11 T 13-10-2018 IPR026891 Fibronectin type III-like domain Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 SUPERFAMILY SSF52279 343 574 6.02E-50 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Gene3D G3DSA:3.40.50.1700 329 572 2.6E-68 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Gene3D G3DSA:3.20.20.300 7 324 3.8E-101 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Gene3D G3DSA:2.60.40.10 573 682 1.4E-14 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 227 245 1.9E-10 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 157 173 1.9E-10 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 PRINTS PR00133 Glycosyl hydrolase family 3 signature 62 81 1.9E-10 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 343 572 5.3E-50 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 SUPERFAMILY SSF51445 11 342 1.47E-95 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0603 f9074ad222ccbeace78ca83744ef8eb2 699 Pfam PF14310 Fibronectin type III-like domain 608 675 6.6E-11 T 13-10-2018 IPR026891 Fibronectin type III-like domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00387 535 650 4.5E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00091 289 355 5.1E-8 T 13-10-2018 IPR000014 PAS domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00091 131 196 4.9E-9 T 13-10-2018 IPR000014 PAS domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Gene3D G3DSA:1.10.287.130 402 486 1.7E-24 T 13-10-2018 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00086 361 403 0.0037 T 13-10-2018 IPR001610 PAC motif Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF47226 769 890 2.94E-9 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Pfam PF00512 His Kinase A (phospho-acceptor) domain 423 487 3.6E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Gene3D G3DSA:3.30.565.10 489 652 3.8E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Pfam PF08448 PAS fold 137 189 1.5E-6 T 13-10-2018 IPR013656 PAS fold-4 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF52172 668 803 6.26E-34 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Gene3D G3DSA:3.30.450.20 120 285 4.7E-18 T 13-10-2018 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 647 3.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 628 3.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 589 3.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00448 669 786 2.3E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF55785 122 199 2.74E-13 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Gene3D G3DSA:3.30.450.20 286 401 1.2E-24 T 13-10-2018 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF55874 477 648 3.41E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Gene3D G3DSA:3.40.50.2300 661 805 4.1E-35 T 13-10-2018 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF52172 2 101 2.42E-7 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF55785 295 401 4.51E-22 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Pfam PF00072 Response regulator receiver domain 671 786 2.2E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SUPERFAMILY SSF47384 408 487 4.9E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Pfam PF13426 PAS domain 299 401 8.8E-17 T 13-10-2018 IPR000014 PAS domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 SMART SM00388 423 488 1.3E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 131 189 1.4E-9 T 13-10-2018 IPR000014 PAS domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 283 408 1.6E-15 T 13-10-2018 IPR000014 PAS domain Spica_0198 9c7a6bb4b85618eb8687e13c66c2fa91 905 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 536 647 4.1E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 Gene3D G3DSA:3.30.70.20 1 33 3.7E-8 T 13-10-2018 Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 Gene3D G3DSA:3.30.70.3270 34 76 3.8E-6 T 13-10-2018 Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 Pfam PF13237 4Fe-4S dicluster domain 6 62 3.5E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2638 0a9e2fbada3e1d36154db864090cb67e 76 SUPERFAMILY SSF54862 3 68 3.2E-16 T 13-10-2018 Spica_0160 5e737398935b20f814adbc374bad15cd 211 SMART SM01160 47 140 1.9E-4 T 13-10-2018 Spica_0160 5e737398935b20f814adbc374bad15cd 211 SUPERFAMILY SSF144091 13 198 4.19E-34 T 13-10-2018 Spica_0160 5e737398935b20f814adbc374bad15cd 211 Gene3D G3DSA:1.20.1540.10 9 203 2.9E-30 T 13-10-2018 IPR035952 Rhomboid-like superfamily Spica_0160 5e737398935b20f814adbc374bad15cd 211 Pfam PF01694 Rhomboid family 52 199 2.0E-31 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spica_1022 398a1ec1f8f14765b5c5a80f73ae0f3d 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 413 1.3E-80 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_1022 398a1ec1f8f14765b5c5a80f73ae0f3d 455 PIRSF PIRSF006603 1 449 7.3E-130 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_1022 398a1ec1f8f14765b5c5a80f73ae0f3d 455 Pfam PF01554 MatE 19 179 9.9E-36 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_1022 398a1ec1f8f14765b5c5a80f73ae0f3d 455 Pfam PF01554 MatE 241 401 1.3E-35 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 Pfam PF04055 Radical SAM superfamily 25 222 1.6E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 Pfam PF13187 4Fe-4S dicluster domain 46 89 1.4E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 6 280 1.6E-102 T 13-10-2018 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 Gene3D G3DSA:3.20.20.70 5 56 8.1E-13 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 Gene3D G3DSA:3.20.20.70 73 278 1.1E-30 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 SUPERFAMILY SSF54862 46 96 1.02E-16 T 13-10-2018 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 13-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 Pfam PF13353 4Fe-4S single cluster domain 17 45 4.7E-6 T 13-10-2018 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 SUPERFAMILY SSF102114 86 264 1.51E-7 T 13-10-2018 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 PIRSF PIRSF000371 1 265 2.6E-69 T 13-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 Spica_0287 3cbdcb1871b6709b7d721a38467ca69f 281 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0468 af3aa56a566a00b7137d3e874a20d43d 130 SUPERFAMILY SSF54211 7 130 1.02E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0468 af3aa56a566a00b7137d3e874a20d43d 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.6E-44 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Spica_0468 af3aa56a566a00b7137d3e874a20d43d 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 30.527 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid Spica_0468 af3aa56a566a00b7137d3e874a20d43d 130 Gene3D G3DSA:3.30.230.10 2 130 2.8E-48 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0468 af3aa56a566a00b7137d3e874a20d43d 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 13-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 Spica_0481 313b6a9a3c62a6df43890b3e99afaeea 118 Hamap MF_00048 UPF0102 protein YraN [yraN]. 3 114 22.42 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 Spica_0481 313b6a9a3c62a6df43890b3e99afaeea 118 Pfam PF02021 Uncharacterised protein family UPF0102 10 101 6.6E-27 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 Spica_0481 313b6a9a3c62a6df43890b3e99afaeea 118 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 4 104 2.2E-24 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 Spica_0481 313b6a9a3c62a6df43890b3e99afaeea 118 Gene3D G3DSA:3.40.1350.10 9 117 7.8E-34 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Spica_0481 313b6a9a3c62a6df43890b3e99afaeea 118 SUPERFAMILY SSF52980 3 106 3.75E-23 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 269 5.7E-72 T 13-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 SUPERFAMILY SSF102522 4 166 2.35E-57 T 13-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 Gene3D G3DSA:3.40.50.10790 1 165 5.6E-50 T 13-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 Gene3D G3DSA:2.40.30.90 169 277 3.2E-32 T 13-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 PIRSF PIRSF006779 1 277 4.2E-93 T 13-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase Spica_2599 1dc98aae2808a34cdd7a2cbcd9401a0f 285 SUPERFAMILY SSF101852 170 275 1.7E-27 T 13-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal Spica_0982 7c22e33f7b2bded8d4f2a1dd89bfdf64 313 Gene3D G3DSA:3.10.310.10 1 145 1.2E-15 T 13-10-2018 Spica_0982 7c22e33f7b2bded8d4f2a1dd89bfdf64 313 SUPERFAMILY SSF54506 3 121 3.14E-10 T 13-10-2018 Spica_0273 a504634f7a7b9459742eeae81baab917 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 195 2.6E-17 T 13-10-2018 Spica_0273 a504634f7a7b9459742eeae81baab917 216 Gene3D G3DSA:3.40.50.1000 13 201 1.4E-24 T 13-10-2018 IPR023214 HAD superfamily Spica_0273 a504634f7a7b9459742eeae81baab917 216 SUPERFAMILY SSF56784 11 202 4.73E-29 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0273 a504634f7a7b9459742eeae81baab917 216 Gene3D G3DSA:1.10.150.520 24 101 1.4E-24 T 13-10-2018 Spica_2532 43f56535261cab7712f18aa869c5eea6 124 SMART SM00448 4 119 2.0E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2532 43f56535261cab7712f18aa869c5eea6 124 Pfam PF00072 Response regulator receiver domain 6 118 3.6E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2532 43f56535261cab7712f18aa869c5eea6 124 Gene3D G3DSA:3.40.50.12740 3 123 1.0E-36 T 13-10-2018 Spica_2532 43f56535261cab7712f18aa869c5eea6 124 SUPERFAMILY SSF52172 1 123 1.85E-35 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1346 fe2186383736298b129f38cd500e438d 1455 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1201 1455 1.9E-10 T 13-10-2018 IPR007452 Translocation and assembly module TamB Spica_2401 27a18db4c5204b1231826c808129e3e9 574 Gene3D G3DSA:3.60.110.10 1 277 4.6E-75 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_2401 27a18db4c5204b1231826c808129e3e9 574 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 1 573 28.428 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 PIRSF PIRSF006630 1 573 1.0E-174 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 Pfam PF00795 Carbon-nitrogen hydrolase 2 232 2.2E-17 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 TIGRFAM TIGR00552 nadE: NAD+ synthetase 300 551 1.2E-62 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 SUPERFAMILY SSF56317 1 258 3.14E-50 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_2401 27a18db4c5204b1231826c808129e3e9 574 Pfam PF02540 NAD synthase 296 548 4.4E-74 T 13-10-2018 IPR022310 NAD/GMP synthase Spica_2401 27a18db4c5204b1231826c808129e3e9 574 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 33 48 - T 13-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 SUPERFAMILY SSF52402 289 556 4.66E-77 T 13-10-2018 Spica_2401 27a18db4c5204b1231826c808129e3e9 574 Gene3D G3DSA:3.40.50.620 292 573 1.2E-111 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1247 e7f5625d42f254b5dbf43fe036dd9eb0 142 Pfam PF01047 MarR family 35 93 1.3E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1247 e7f5625d42f254b5dbf43fe036dd9eb0 142 SMART SM00347 28 128 9.8E-24 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Spica_1247 e7f5625d42f254b5dbf43fe036dd9eb0 142 SUPERFAMILY SSF46785 2 140 2.56E-33 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1247 e7f5625d42f254b5dbf43fe036dd9eb0 142 Gene3D G3DSA:1.10.10.10 1 141 3.8E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2857 db3bbd43f39ece0081927fd2a32f7817 641 Pfam PF00501 AMP-binding enzyme 11 493 1.9E-85 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_2857 db3bbd43f39ece0081927fd2a32f7817 641 SUPERFAMILY SSF56801 3 624 2.49E-99 T 13-10-2018 Spica_2857 db3bbd43f39ece0081927fd2a32f7817 641 Gene3D G3DSA:3.40.50.12780 1 306 4.0E-41 T 13-10-2018 Spica_2857 db3bbd43f39ece0081927fd2a32f7817 641 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_2857 db3bbd43f39ece0081927fd2a32f7817 641 Gene3D G3DSA:3.40.50.12780 342 487 6.2E-42 T 13-10-2018 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 383 531 6.5E-48 T 13-10-2018 IPR001162 UvrC family homology region Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Hamap MF_00203 UvrABC system protein C [uvrC]. 11 597 27.516 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 SUPERFAMILY SSF46600 194 243 1.96E-11 T 13-10-2018 IPR036876 UVR domain superfamily Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 SMART SM00465 24 104 2.4E-19 T 13-10-2018 IPR000305 GIY-YIG endonuclease Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 SUPERFAMILY SSF47781 490 596 3.81E-13 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Gene3D G3DSA:3.30.420.340 376 539 7.0E-52 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Pfam PF02151 UvrB/uvrC motif 208 241 5.5E-10 T 13-10-2018 IPR001943 UVR domain GO:0005515 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Pfam PF01541 GIY-YIG catalytic domain 25 99 6.7E-10 T 13-10-2018 IPR000305 GIY-YIG endonuclease Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 SUPERFAMILY SSF82771 25 106 2.88E-20 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Gene3D G3DSA:3.40.1440.10 11 108 7.3E-32 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 16 578 8.3E-168 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Spica_2729 ea716ee6ea4781354f808dbcba8b0a12 642 Gene3D G3DSA:1.10.150.20 540 597 2.5E-11 T 13-10-2018 Spica_0438 a9dfda69051db0da498506d574c7e192 273 Gene3D G3DSA:3.40.50.300 1 183 4.4E-43 T 13-10-2018 Spica_0438 a9dfda69051db0da498506d574c7e192 273 Pfam PF13189 Cytidylate kinase-like family 3 167 5.4E-38 T 13-10-2018 Spica_0438 a9dfda69051db0da498506d574c7e192 273 Pfam PF04972 BON domain 205 265 1.1E-7 T 13-10-2018 IPR007055 BON domain Spica_1014 c5d5e0fb8ee693089a11a07b92d8979f 518 Gene3D G3DSA:3.20.20.300 59 194 2.6E-7 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_1014 c5d5e0fb8ee693089a11a07b92d8979f 518 Gene3D G3DSA:3.20.20.300 218 493 2.4E-56 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_1014 c5d5e0fb8ee693089a11a07b92d8979f 518 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 241 483 5.2E-36 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_1014 c5d5e0fb8ee693089a11a07b92d8979f 518 SUPERFAMILY SSF51445 62 501 1.26E-45 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1257 1b3ae797dc9e6ace0e78baf238cbb4d1 871 SUPERFAMILY SSF102114 261 500 2.09E-16 T 13-10-2018 Spica_1257 1b3ae797dc9e6ace0e78baf238cbb4d1 871 Gene3D G3DSA:3.80.30.20 270 452 3.4E-11 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1257 1b3ae797dc9e6ace0e78baf238cbb4d1 871 Pfam PF04055 Radical SAM superfamily 281 437 5.1E-9 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1257 1b3ae797dc9e6ace0e78baf238cbb4d1 871 SMART SM00729 272 486 0.001 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 SUPERFAMILY SSF52317 3 193 1.18E-46 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 192 34.233 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 PIRSF PIRSF005639 1 195 8.8E-67 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 Pfam PF01174 SNO glutamine amidotransferase family 6 191 6.8E-53 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 190 3.6E-61 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 ProSitePatterns PS01236 PdxT/SNO family family signature. 42 52 - T 13-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0932 ad78be5f5fbcf376226a3bedb790ad78 195 Gene3D G3DSA:3.40.50.880 2 195 5.1E-67 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1176 05d246710452244803fc0a0aec948da4 673 SUPERFAMILY SSF48452 328 559 8.98E-35 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13432 Tetratricopeptide repeat 47 90 0.0026 T 13-10-2018 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13432 Tetratricopeptide repeat 359 416 1.3E-9 T 13-10-2018 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13432 Tetratricopeptide repeat 293 346 0.0063 T 13-10-2018 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13432 Tetratricopeptide repeat 598 650 2.0E-7 T 13-10-2018 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13432 Tetratricopeptide repeat 530 586 8.3E-5 T 13-10-2018 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 321 354 24.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 491 524 0.97 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 525 558 11.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 355 388 4.6E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 593 626 0.0079 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 287 320 17.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 559 592 2.0E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 389 422 1.1E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 627 660 5.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 457 490 43.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SMART SM00028 423 456 0.14 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SUPERFAMILY SSF48452 520 658 3.54E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 SUPERFAMILY SSF48452 203 370 3.0E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Gene3D G3DSA:1.25.40.10 328 393 7.7E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Gene3D G3DSA:1.25.40.10 191 327 6.4E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Gene3D G3DSA:1.25.40.10 394 490 4.2E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Gene3D G3DSA:1.25.40.10 491 671 5.4E-36 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1176 05d246710452244803fc0a0aec948da4 673 Pfam PF13181 Tetratricopeptide repeat 494 523 0.21 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 564 49.079 T 13-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 SUPERFAMILY SSF50715 350 562 3.35E-69 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 30 566 1.2E-205 T 13-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Gene3D G3DSA:2.40.240.10 352 561 3.2E-79 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 SUPERFAMILY SSF52374 30 356 3.1E-93 T 13-10-2018 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Gene3D G3DSA:3.40.50.620 1 351 2.8E-129 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 45 5.6E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 62 75 5.6E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 221 231 5.6E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Gene3D G3DSA:2.40.240.10 358 477 3.2E-79 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 350 544 4.4E-58 T 13-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0658 79ad524e2906b2f338a6e9b59320bc3d 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 30 347 3.3E-100 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 Pfam PF00672 HAMP domain 204 252 1.7E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 SUPERFAMILY SSF158472 204 255 1.26E-10 T 13-10-2018 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 SUPERFAMILY SSF55874 333 468 2.38E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 469 1.9E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 SMART SM00304 203 256 1.5E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 Gene3D G3DSA:1.20.1480.50 165 263 1.1E-15 T 13-10-2018 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 Pfam PF06580 Histidine kinase 279 357 4.2E-19 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_2632 3159b13e3170fe5713cc5978dda56a55 486 Gene3D G3DSA:3.30.565.10 336 472 7.1E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Pfam PF05697 Bacterial trigger factor protein (TF) 20 167 2.4E-35 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 TIGRFAM TIGR00115 tig: trigger factor 28 447 6.4E-111 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Gene3D G3DSA:1.10.3120.10 139 453 2.3E-76 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 288 448 3.0E-35 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Gene3D G3DSA:3.10.50.40 173 272 2.3E-76 T 13-10-2018 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 SUPERFAMILY SSF109998 274 455 2.75E-38 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Spica_1112 68f500b665bce0415f13ec41383b7eda 469 PIRSF PIRSF003095 17 469 1.6E-107 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 SUPERFAMILY SSF102735 20 154 1.02E-26 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 183 255 3.6E-7 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Gene3D G3DSA:3.30.70.1050 16 138 4.0E-24 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 SUPERFAMILY SSF54534 155 272 1.65E-22 T 13-10-2018 Spica_1112 68f500b665bce0415f13ec41383b7eda 469 Hamap MF_00303 Trigger factor [tig]. 17 454 18.811 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Spica_2374 28ec73c2679916892436a6648b727c3e 74 Gene3D G3DSA:2.40.50.140 2 72 9.6E-35 T 13-10-2018 Spica_2374 28ec73c2679916892436a6648b727c3e 74 SUPERFAMILY SSF50249 2 72 6.69E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2374 28ec73c2679916892436a6648b727c3e 74 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 72 6.8E-34 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Spica_2374 28ec73c2679916892436a6648b727c3e 74 SMART SM00316 4 74 1.3E-4 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2374 28ec73c2679916892436a6648b727c3e 74 Pfam PF01176 Translation initiation factor 1A / IF-1 7 72 1.4E-25 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Spica_2374 28ec73c2679916892436a6648b727c3e 74 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 74 26.771 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Spica_0358 b06bd22ce09a6ecdf1cd11920d06eeae 145 Gene3D G3DSA:2.30.30.90 1 84 3.3E-20 T 13-10-2018 IPR038157 Ferrous iron transporter, core domain Spica_0358 b06bd22ce09a6ecdf1cd11920d06eeae 145 SUPERFAMILY SSF50037 3 74 1.3E-14 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal Spica_0358 b06bd22ce09a6ecdf1cd11920d06eeae 145 SMART SM00899 1 73 2.6E-16 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Spica_0358 b06bd22ce09a6ecdf1cd11920d06eeae 145 Pfam PF04023 FeoA domain 1 73 3.9E-15 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Spica_0914 f99b2543f9ffbe859f0df81738982435 265 PIRSF PIRSF017388 9 265 5.2E-52 T 13-10-2018 IPR012354 Esterase/lipase GO:0052689 Spica_0914 f99b2543f9ffbe859f0df81738982435 265 SUPERFAMILY SSF53474 19 263 5.72E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_0914 f99b2543f9ffbe859f0df81738982435 265 Gene3D G3DSA:3.40.50.1820 10 262 1.1E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_0914 f99b2543f9ffbe859f0df81738982435 265 Pfam PF12146 Serine aminopeptidase, S33 27 246 2.9E-11 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 Gene3D G3DSA:3.30.450.40 31 194 7.7E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 SMART SM00267 188 362 1.9E-60 T 13-10-2018 IPR000160 GGDEF domain Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 Pfam PF00990 Diguanylate cyclase, GGDEF domain 202 358 4.0E-48 T 13-10-2018 IPR000160 GGDEF domain Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 199 361 3.4E-52 T 13-10-2018 IPR000160 GGDEF domain Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 Gene3D G3DSA:3.30.70.270 196 364 1.3E-54 T 13-10-2018 Spica_0478 225fa838ff11fac12fc9e5d2865607d4 380 SUPERFAMILY SSF55073 206 363 7.61E-48 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 280 295 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 407 416 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 218 231 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Pfam PF02954 Bacterial regulatory protein, Fis family 461 495 5.2E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Gene3D G3DSA:3.30.450.40 6 178 9.0E-45 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Gene3D G3DSA:1.10.10.60 443 500 2.4E-14 T 13-10-2018 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 SUPERFAMILY SSF46689 407 498 1.12E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Gene3D G3DSA:1.10.8.60 367 437 3.9E-28 T 13-10-2018 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 SMART SM00065 26 175 7.5E-22 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 SMART SM00382 214 358 1.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 SUPERFAMILY SSF55781 8 184 5.89E-44 T 13-10-2018 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Gene3D G3DSA:3.40.50.300 179 365 3.9E-64 T 13-10-2018 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 SUPERFAMILY SSF52540 195 435 2.96E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Pfam PF00158 Sigma-54 interaction domain 194 360 6.3E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_1380 5fe8e3d879c7b16d128068cc479fd337 503 Pfam PF13185 GAF domain 26 166 2.0E-18 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1831 026ae1863a22568c03918f34ce13cff2 411 Gene3D G3DSA:1.20.1640.10 209 408 2.0E-13 T 13-10-2018 Spica_1831 026ae1863a22568c03918f34ce13cff2 411 PRINTS PR01755 Bacterial translocase SecF protein signature 33 48 3.5E-26 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1831 026ae1863a22568c03918f34ce13cff2 411 PRINTS PR01755 Bacterial translocase SecF protein signature 250 264 3.5E-26 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1831 026ae1863a22568c03918f34ce13cff2 411 PRINTS PR01755 Bacterial translocase SecF protein signature 330 345 3.5E-26 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1831 026ae1863a22568c03918f34ce13cff2 411 PRINTS PR01755 Bacterial translocase SecF protein signature 298 316 3.5E-26 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1831 026ae1863a22568c03918f34ce13cff2 411 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 7 393 27.53 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spica_1831 026ae1863a22568c03918f34ce13cff2 411 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 34 382 1.0E-71 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Spica_1831 026ae1863a22568c03918f34ce13cff2 411 Pfam PF02355 Protein export membrane protein 211 391 5.3E-60 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spica_1831 026ae1863a22568c03918f34ce13cff2 411 SUPERFAMILY SSF82866 221 395 4.71E-38 T 13-10-2018 Spica_1831 026ae1863a22568c03918f34ce13cff2 411 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 194 379 2.9E-54 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1050 5301a24273128b10a6d89123e8930bb7 532 SUPERFAMILY SSF88688 421 530 4.9E-32 T 13-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily Spica_1050 5301a24273128b10a6d89123e8930bb7 532 Gene3D G3DSA:1.20.1430.10 421 532 7.3E-36 T 13-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 Spica_1050 5301a24273128b10a6d89123e8930bb7 532 Gene3D G3DSA:3.20.110.10 5 410 2.1E-141 T 13-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily Spica_1050 5301a24273128b10a6d89123e8930bb7 532 SUPERFAMILY SSF88713 7 417 3.71E-92 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1050 5301a24273128b10a6d89123e8930bb7 532 Pfam PF03065 Glycosyl hydrolase family 57 9 423 9.9E-35 T 13-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 Spica_1050 5301a24273128b10a6d89123e8930bb7 532 Pfam PF09210 Domain of unknown function (DUF1957) 428 528 2.0E-33 T 13-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 6 379 1.5E-141 T 13-10-2018 IPR020823 Cell division protein FtsA Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 417 30.011 T 13-10-2018 IPR020823 Cell division protein FtsA Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Pfam PF02491 SHS2 domain inserted in FTSA 82 164 1.5E-32 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 SUPERFAMILY SSF53067 200 379 2.16E-45 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Pfam PF14450 Cell division protein FtsA 209 376 2.3E-23 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Gene3D G3DSA:3.30.420.40 199 354 5.6E-121 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 PIRSF PIRSF003101 1 417 4.2E-147 T 13-10-2018 IPR020823 Cell division protein FtsA Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Gene3D G3DSA:3.30.420.40 10 374 5.6E-121 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Pfam PF14450 Cell division protein FtsA 8 187 1.5E-9 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 SMART SM00842 7 198 7.4E-92 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Gene3D G3DSA:3.90.640.10 237 302 5.6E-121 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 Gene3D G3DSA:3.30.1490.110 84 171 5.6E-121 T 13-10-2018 Spica_1682 e77f153c82b5a338aa1e8f643b2ee822 418 SUPERFAMILY SSF53067 6 199 4.23E-56 T 13-10-2018 Spica_0844 c78321a2b777c89c628a7c3e5f49a396 564 Gene3D G3DSA:3.40.50.1700 403 562 6.3E-11 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Spica_0844 c78321a2b777c89c628a7c3e5f49a396 564 SUPERFAMILY SSF51445 36 386 7.26E-83 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0844 c78321a2b777c89c628a7c3e5f49a396 564 SUPERFAMILY SSF52279 474 559 3.14E-5 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Spica_0844 c78321a2b777c89c628a7c3e5f49a396 564 Gene3D G3DSA:3.20.20.300 45 378 1.9E-93 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_0844 c78321a2b777c89c628a7c3e5f49a396 564 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 51 373 2.6E-73 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0778 47065c291de81d046bc713305f1f61f8 177 Pfam PF00156 Phosphoribosyl transferase domain 28 147 3.0E-22 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_0778 47065c291de81d046bc713305f1f61f8 177 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 7 174 2.7E-57 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 Spica_0778 47065c291de81d046bc713305f1f61f8 177 Gene3D G3DSA:3.40.50.2020 2 176 8.9E-61 T 13-10-2018 Spica_0778 47065c291de81d046bc713305f1f61f8 177 SUPERFAMILY SSF53271 9 172 1.7E-47 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_0778 47065c291de81d046bc713305f1f61f8 177 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 7 174 34.841 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Gene3D G3DSA:3.40.50.2300 115 249 5.4E-28 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 SUPERFAMILY SSF47384 562 643 1.84E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Gene3D G3DSA:1.10.10.60 1060 1113 8.0E-18 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1063 1105 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 SUPERFAMILY SSF53822 5 288 5.69E-30 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Gene3D G3DSA:3.40.50.2300 58 265 5.4E-28 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Gene3D G3DSA:1.10.287.130 563 644 5.1E-6 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1093 1109 3.6E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1078 1093 3.6E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Gene3D G3DSA:1.10.10.60 1009 1059 2.4E-11 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 SMART SM00342 1029 1109 3.8E-28 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 SUPERFAMILY SSF46689 1062 1111 2.91E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Pfam PF13377 Periplasmic binding protein-like domain 124 288 4.0E-17 T 13-10-2018 Spica_0632 0b890315372f17bbc31f3f48f9cfd26f 1113 Pfam PF12833 Helix-turn-helix domain 1032 1110 2.5E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2760 15b34d7fa629555439a1cf60b4e2e49e 246 Pfam PF00005 ABC transporter 25 171 4.4E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2760 15b34d7fa629555439a1cf60b4e2e49e 246 SMART SM00382 33 244 4.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2760 15b34d7fa629555439a1cf60b4e2e49e 246 SUPERFAMILY SSF52540 9 239 2.66E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2760 15b34d7fa629555439a1cf60b4e2e49e 246 Gene3D G3DSA:3.40.50.300 7 246 1.0E-66 T 13-10-2018 Spica_2760 15b34d7fa629555439a1cf60b4e2e49e 246 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 9 246 6.7E-108 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 Pfam PF08502 LeuA allosteric (dimerisation) domain 417 559 1.7E-29 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 29 45 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 Gene3D G3DSA:3.30.160.270 422 558 4.8E-8 T 13-10-2018 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 22 565 3.1E-197 T 13-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 245 258 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 Gene3D G3DSA:3.20.20.70 21 368 7.4E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 SMART SM00917 417 560 6.5E-35 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 Pfam PF00682 HMGL-like 245 296 1.3E-16 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 Pfam PF00682 HMGL-like 21 216 1.8E-26 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 SUPERFAMILY SSF110921 443 556 1.44E-21 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Spica_2674 ad3742453f132dae0cf26803a0686ab1 572 SUPERFAMILY SSF51569 18 335 2.69E-75 T 13-10-2018 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 SUPERFAMILY SSF51713 4 374 6.28E-145 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 375 3.9E-144 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 373 51.983 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 12 375 4.2E-151 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 370 6.0E-79 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_1362 88ba9639c2339f4a3f037e7be21d79ae 382 Gene3D G3DSA:3.20.20.105 1 378 2.2E-153 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Spica_0201 013810173d3872561ebb1d4d5ff57840 195 Pfam PF02132 RecR protein 37 75 2.0E-16 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger Spica_0201 013810173d3872561ebb1d4d5ff57840 195 SMART SM00493 77 162 9.6E-9 T 13-10-2018 IPR006171 TOPRIM domain Spica_0201 013810173d3872561ebb1d4d5ff57840 195 TIGRFAM TIGR00615 recR: recombination protein RecR 2 192 1.0E-76 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Spica_0201 013810173d3872561ebb1d4d5ff57840 195 Gene3D G3DSA:1.10.8.420 1 49 1.3E-13 T 13-10-2018 Spica_0201 013810173d3872561ebb1d4d5ff57840 195 Hamap MF_00017 Recombination protein RecR [recR]. 1 195 94.034 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Spica_0201 013810173d3872561ebb1d4d5ff57840 195 ProSitePatterns PS01300 RecR protein signature. 54 75 - T 13-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 Spica_0201 013810173d3872561ebb1d4d5ff57840 195 Pfam PF13662 Toprim domain 79 168 6.0E-22 T 13-10-2018 IPR006171 TOPRIM domain Spica_0201 013810173d3872561ebb1d4d5ff57840 195 SUPERFAMILY SSF111304 2 195 1.96E-72 T 13-10-2018 IPR023627 Recombination protein RecR Spica_0201 013810173d3872561ebb1d4d5ff57840 195 Gene3D G3DSA:3.40.1360.10 74 194 2.8E-45 T 13-10-2018 Spica_1099 ad56f76cc2b218451dd504e431ccab84 320 Gene3D G3DSA:3.10.310.30 205 320 5.5E-23 T 13-10-2018 Spica_1099 ad56f76cc2b218451dd504e431ccab84 320 SUPERFAMILY SSF64182 18 303 2.35E-50 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_1099 ad56f76cc2b218451dd504e431ccab84 320 Gene3D G3DSA:3.90.1640.10 5 204 5.1E-43 T 13-10-2018 Spica_1099 ad56f76cc2b218451dd504e431ccab84 320 Pfam PF01368 DHH family 19 156 6.4E-11 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_1099 ad56f76cc2b218451dd504e431ccab84 320 Pfam PF02272 DHHA1 domain 183 306 1.1E-8 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Spica_1591 3e23c706b45035bb5739a32e50983414 196 ProSitePatterns PS00194 Thioredoxin family active site. 81 99 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Spica_1591 3e23c706b45035bb5739a32e50983414 196 SUPERFAMILY SSF52833 10 178 3.41E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_1591 3e23c706b45035bb5739a32e50983414 196 Pfam PF00578 AhpC/TSA family 57 166 9.8E-25 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_1591 3e23c706b45035bb5739a32e50983414 196 Gene3D G3DSA:3.40.30.10 32 193 2.4E-38 T 13-10-2018 Spica_1020 ae948e954f7d5e8636577e15167e55af 163 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 129 3.7E-28 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_1020 ae948e954f7d5e8636577e15167e55af 163 Gene3D G3DSA:3.40.140.10 7 161 1.3E-44 T 13-10-2018 Spica_1020 ae948e954f7d5e8636577e15167e55af 163 PIRSF PIRSF006019 1 162 3.1E-44 T 13-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Spica_1020 ae948e954f7d5e8636577e15167e55af 163 SUPERFAMILY SSF53927 12 154 4.61E-34 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Spica_1020 ae948e954f7d5e8636577e15167e55af 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 84 119 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spica_2848 701d17ad30a7e3470868267c278f71c5 427 SUPERFAMILY SSF53850 21 419 1.09E-82 T 13-10-2018 Spica_2848 701d17ad30a7e3470868267c278f71c5 427 Pfam PF01547 Bacterial extracellular solute-binding protein 36 327 1.1E-51 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2848 701d17ad30a7e3470868267c278f71c5 427 Gene3D G3DSA:3.40.190.10 37 369 6.5E-102 T 13-10-2018 Spica_2848 701d17ad30a7e3470868267c278f71c5 427 Gene3D G3DSA:3.40.190.10 143 397 6.5E-102 T 13-10-2018 Spica_0089 24df5a1ab2f3a8bbd5ec7717cce176d4 621 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 388 609 1.8E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0089 24df5a1ab2f3a8bbd5ec7717cce176d4 621 Gene3D G3DSA:1.10.3720.10 344 614 1.3E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0089 24df5a1ab2f3a8bbd5ec7717cce176d4 621 SUPERFAMILY SSF161098 335 602 5.63E-42 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0089 24df5a1ab2f3a8bbd5ec7717cce176d4 621 SUPERFAMILY SSF160964 250 320 1.31E-6 T 13-10-2018 Spica_1941 2b33cdd895b73fac1a60768ca851ab23 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 17.172 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1941 2b33cdd895b73fac1a60768ca851ab23 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.3E-22 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1941 2b33cdd895b73fac1a60768ca851ab23 63 Pfam PF00830 Ribosomal L28 family 3 56 7.7E-22 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1941 2b33cdd895b73fac1a60768ca851ab23 63 SUPERFAMILY SSF143800 1 61 2.75E-23 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1941 2b33cdd895b73fac1a60768ca851ab23 63 Gene3D G3DSA:2.30.170.40 2 63 5.6E-20 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 Gene3D G3DSA:3.40.50.720 1 136 4.5E-25 T 13-10-2018 Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 Gene3D G3DSA:3.30.70.1450 137 214 1.3E-16 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 SUPERFAMILY SSF116726 136 216 3.53E-14 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 SUPERFAMILY SSF51735 2 132 7.42E-24 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 Pfam PF02080 TrkA-C domain 149 213 1.5E-8 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spica_2843 80c5bf6b15b20f3404f6c0a2369f918f 236 Pfam PF02254 TrkA-N domain 4 119 4.3E-18 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spica_0728 a29fdc34a5efca258ad4478808483615 346 SUPERFAMILY SSF53822 62 338 1.23E-55 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0728 a29fdc34a5efca258ad4478808483615 346 Pfam PF13377 Periplasmic binding protein-like domain 175 335 3.5E-31 T 13-10-2018 Spica_0728 a29fdc34a5efca258ad4478808483615 346 SMART SM00354 1 71 1.3E-31 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0728 a29fdc34a5efca258ad4478808483615 346 Gene3D G3DSA:1.10.260.40 1 59 2.4E-22 T 13-10-2018 Spica_0728 a29fdc34a5efca258ad4478808483615 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 2.3E-18 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0728 a29fdc34a5efca258ad4478808483615 346 Gene3D G3DSA:3.40.50.2300 165 332 5.3E-62 T 13-10-2018 Spica_0728 a29fdc34a5efca258ad4478808483615 346 SUPERFAMILY SSF47413 1 59 8.96E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0728 a29fdc34a5efca258ad4478808483615 346 Gene3D G3DSA:3.40.50.2300 62 327 5.3E-62 T 13-10-2018 Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 12 246 7.4E-95 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.8E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.8E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.8E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 SUPERFAMILY SSF51735 8 247 1.91E-86 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 Gene3D G3DSA:3.40.50.720 1 247 2.8E-85 T 13-10-2018 Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 187 1.3E-4 T 13-10-2018 Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 1.7E-69 T 13-10-2018 Spica_2037 4cc6010585cb3e1ef335dce087d104ba 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_2029 9ba0171485f4c651532f85bc05afda03 389 Pfam PF01594 AI-2E family transporter 23 344 3.3E-51 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like Spica_1718 3b3c8d6c8b0133e57f0ff3692a784cbe 496 Pfam PF01940 Integral membrane protein DUF92 243 484 9.6E-68 T 13-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 Spica_0122 933a08f5d6203fd0f078f5b132d72e35 445 Pfam PF07730 Histidine kinase 245 311 1.7E-16 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_0122 933a08f5d6203fd0f078f5b132d72e35 445 SUPERFAMILY SSF55874 325 437 2.36E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0122 933a08f5d6203fd0f078f5b132d72e35 445 Gene3D G3DSA:3.30.565.10 310 440 1.0E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0122 933a08f5d6203fd0f078f5b132d72e35 445 SMART SM00387 350 440 0.0018 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0122 933a08f5d6203fd0f078f5b132d72e35 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 437 7.6E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0916 89eb4cf1c701b3196b81f28e2cfb96e4 583 SMART SM00382 323 458 1.4E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0916 89eb4cf1c701b3196b81f28e2cfb96e4 583 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 328 452 8.4E-20 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_0916 89eb4cf1c701b3196b81f28e2cfb96e4 583 Gene3D G3DSA:1.10.8.60 459 531 1.3E-5 T 13-10-2018 Spica_0916 89eb4cf1c701b3196b81f28e2cfb96e4 583 SUPERFAMILY SSF52540 293 549 3.69E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0916 89eb4cf1c701b3196b81f28e2cfb96e4 583 Gene3D G3DSA:3.40.50.300 287 454 4.0E-26 T 13-10-2018 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Gene3D G3DSA:1.10.340.30 22 133 9.1E-72 T 13-10-2018 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Gene3D G3DSA:1.10.1670.10 14 204 9.1E-72 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Hamap MF_00942 Endonuclease III [nth]. 1 210 35.526 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 SUPERFAMILY SSF48150 2 206 9.89E-66 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 188 204 3.4E-5 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Pfam PF00633 Helix-hairpin-helix motif 101 128 1.4E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 SMART SM00525 187 207 8.0E-5 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 PIRSF PIRSF001435 1 211 2.9E-48 T 13-10-2018 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 TIGRFAM TIGR01083 nth: endonuclease III 7 195 3.6E-69 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 SMART SM00478 39 186 2.3E-51 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_1180 29ed3f48d1707cf1357818357c0c04df 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 166 6.5E-24 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_0142 86de2a624729f5afbd94481c9fd043e1 203 Gene3D G3DSA:3.10.50.40 29 179 9.1E-57 T 13-10-2018 Spica_0142 86de2a624729f5afbd94481c9fd043e1 203 Gene3D G3DSA:2.40.10.330 97 147 9.1E-57 T 13-10-2018 Spica_0142 86de2a624729f5afbd94481c9fd043e1 203 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 31 136 3.3E-11 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_0142 86de2a624729f5afbd94481c9fd043e1 203 SUPERFAMILY SSF54534 29 166 1.92E-36 T 13-10-2018 Spica_1490 43d2b21b7a4975660a702b8068a89b09 95 SUPERFAMILY SSF103007 1 90 8.11E-23 T 13-10-2018 IPR036746 TT1725-like superfamily Spica_1490 43d2b21b7a4975660a702b8068a89b09 95 Gene3D G3DSA:3.30.70.1120 1 95 1.1E-21 T 13-10-2018 IPR036746 TT1725-like superfamily Spica_1490 43d2b21b7a4975660a702b8068a89b09 95 Pfam PF04456 Protein of unknown function (DUF503) 3 89 6.0E-27 T 13-10-2018 IPR007546 Protein of unknown function DUF503 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 Pfam PF01311 Bacterial export proteins, family 1 11 245 1.4E-54 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 11 255 9.4E-59 T 13-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 2.1E-24 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 2.1E-24 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 18 39 2.1E-24 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Spica_1527 cbc3ac72b58fd1f1281b4fc905041fc4 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 78 97 2.1E-24 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Spica_0994 b4eb926bf88bf11f5abb91b46c6a1c9e 320 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 218 295 8.0E-19 T 13-10-2018 IPR039561 Peptidase M15C GO:0008233 Spica_0994 b4eb926bf88bf11f5abb91b46c6a1c9e 320 SUPERFAMILY SSF55166 207 299 1.73E-16 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Spica_0994 b4eb926bf88bf11f5abb91b46c6a1c9e 320 Gene3D G3DSA:3.30.1380.10 172 294 1.6E-14 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Spica_0285 845b1cb1ecda8b7366fae687953705f7 386 Pfam PF13173 AAA domain 18 133 7.0E-24 T 13-10-2018 Spica_0285 845b1cb1ecda8b7366fae687953705f7 386 SUPERFAMILY SSF52980 279 354 2.39E-5 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_0285 845b1cb1ecda8b7366fae687953705f7 386 SUPERFAMILY SSF52540 18 134 6.07E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0285 845b1cb1ecda8b7366fae687953705f7 386 Pfam PF13635 Domain of unknown function (DUF4143) 176 335 4.9E-27 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 152 172 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 SMART SM00729 148 372 2.4E-39 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 SUPERFAMILY SSF102114 147 374 5.1E-51 T 13-10-2018 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Pfam PF00919 Uncharacterized protein family UPF0004 4 100 6.7E-27 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Pfam PF04055 Radical SAM superfamily 153 329 3.1E-20 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Gene3D G3DSA:3.40.50.12160 4 130 2.3E-32 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 11 446 1.1E-129 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 446 1.2E-114 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Gene3D G3DSA:3.80.30.20 148 386 1.4E-77 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 3 450 54.829 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Spica_0462 079432f6f29e0034f39d7e29c3084bab 454 Gene3D G3DSA:2.40.50.140 387 452 5.3E-10 T 13-10-2018 Spica_0153 3e618efad13f4ba46532a5a53d2d90a2 243 Pfam PF00005 ABC transporter 19 163 2.2E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0153 3e618efad13f4ba46532a5a53d2d90a2 243 SUPERFAMILY SSF52540 3 226 4.75E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0153 3e618efad13f4ba46532a5a53d2d90a2 243 Gene3D G3DSA:3.40.50.300 1 229 2.1E-58 T 13-10-2018 Spica_0153 3e618efad13f4ba46532a5a53d2d90a2 243 SMART SM00382 28 219 1.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0153 3e618efad13f4ba46532a5a53d2d90a2 243 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1343 53e491e639257df005a0b72c2782c239 339 Pfam PF02547 Queuosine biosynthesis protein 4 338 1.4E-129 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Spica_1343 53e491e639257df005a0b72c2782c239 339 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 339 44.303 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Spica_1343 53e491e639257df005a0b72c2782c239 339 Gene3D G3DSA:3.40.1780.10 14 338 1.2E-117 T 13-10-2018 Spica_1343 53e491e639257df005a0b72c2782c239 339 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 338 8.0E-123 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Spica_1343 53e491e639257df005a0b72c2782c239 339 SUPERFAMILY SSF111337 1 338 2.75E-126 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Spica_1343 53e491e639257df005a0b72c2782c239 339 Gene3D G3DSA:2.40.10.240 64 161 1.2E-117 T 13-10-2018 Spica_0442 ee6b23685f1f8edfc6925d9fc7a8a58f 192 PIRSF PIRSF000847 1 192 1.6E-38 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Spica_0442 ee6b23685f1f8edfc6925d9fc7a8a58f 192 Gene3D G3DSA:1.20.120.1760 3 182 2.6E-11 T 13-10-2018 Spica_0442 ee6b23685f1f8edfc6925d9fc7a8a58f 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spica_0442 ee6b23685f1f8edfc6925d9fc7a8a58f 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 192 1.3E-33 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Spica_0442 ee6b23685f1f8edfc6925d9fc7a8a58f 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 1.4E-12 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spica_2100 6d79564a70c2317da37d1eaa012d6eaf 76 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 3 75 5.3E-30 T 13-10-2018 IPR011911 Glutaredoxin-like protein, YruB Spica_2100 6d79564a70c2317da37d1eaa012d6eaf 76 Gene3D G3DSA:3.40.30.10 2 75 1.9E-23 T 13-10-2018 Spica_2100 6d79564a70c2317da37d1eaa012d6eaf 76 ProSitePatterns PS00195 Glutaredoxin active site. 5 21 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 Spica_2100 6d79564a70c2317da37d1eaa012d6eaf 76 Pfam PF00462 Glutaredoxin 4 62 1.0E-16 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Spica_2100 6d79564a70c2317da37d1eaa012d6eaf 76 SUPERFAMILY SSF52833 1 75 2.81E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 385 1.1E-137 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 Gene3D G3DSA:3.40.640.10 47 296 2.5E-139 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 PIRSF PIRSF000521 1 153 1.2E-13 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 PIRSF PIRSF000521 166 388 3.9E-33 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 388 64.649 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 SUPERFAMILY SSF53383 3 386 6.46E-122 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 Gene3D G3DSA:3.90.1150.10 12 378 2.5E-139 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 214 251 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spica_0886 fae488af8a4b30512be49e3e1fbb3cc5 392 Pfam PF00202 Aminotransferase class-III 8 385 1.3E-115 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 333 1.7E-82 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 Pfam PF01867 CRISPR associated protein Cas1 8 298 3.7E-100 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 Gene3D G3DSA:1.20.120.920 85 342 3.1E-69 T 13-10-2018 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 328 25.264 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 Gene3D G3DSA:3.100.10.20 6 84 1.3E-17 T 13-10-2018 Spica_1924 2e4fcab1cdf7cdd007e4ed4fc207ddde 343 TIGRFAM TIGR03640 cas1_DVULG: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG 3 342 4.1E-142 T 13-10-2018 IPR019856 CRISPR-associated protein Cas1, DVULG subtype GO:0004520|GO:0043571|GO:0046872 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 Pfam PF00072 Response regulator receiver domain 5 114 6.9E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 SUPERFAMILY SSF46894 132 228 3.12E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 Gene3D G3DSA:1.10.10.10 130 230 9.5E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0733 62690171f0e864957aea0793bd0b16e0 235 SUPERFAMILY SSF52172 4 128 1.99E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0733 62690171f0e864957aea0793bd0b16e0 235 SMART SM00862 151 227 4.8E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 Gene3D G3DSA:3.40.50.2300 2 129 3.3E-34 T 13-10-2018 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 2.1E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_0733 62690171f0e864957aea0793bd0b16e0 235 SMART SM00448 3 113 2.4E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 375 40.681 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Pfam PF13288 DXP reductoisomerase C-terminal domain 255 369 3.8E-32 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 SUPERFAMILY SSF51735 3 144 9.34E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Gene3D G3DSA:1.10.1740.10 296 380 1.3E-23 T 13-10-2018 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 PIRSF PIRSF006205 2 381 2.2E-130 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 SUPERFAMILY SSF69055 286 378 1.7E-24 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 140 223 8.4E-37 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Gene3D G3DSA:3.40.50.720 1 144 1.2E-41 T 13-10-2018 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 126 5.0E-32 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 SUPERFAMILY SSF55347 120 258 9.16E-53 T 13-10-2018 Spica_1420 e40dc09473264ec6381390997e6a31f1 381 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 376 2.3E-112 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 423 2.5E-154 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 Gene3D G3DSA:3.65.10.10 21 228 5.1E-151 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 414 5.6E-65 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 424 37.087 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 Gene3D G3DSA:3.65.10.10 6 421 5.1E-151 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Spica_0225 ffcfb84e2852eae2073f4c47746f0b3d 427 SUPERFAMILY SSF55205 1 425 8.18E-112 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 Gene3D G3DSA:3.30.70.1150 84 164 1.1E-29 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.1E-28 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 SUPERFAMILY SSF55021 81 162 1.95E-25 T 13-10-2018 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 6.0E-24 T 13-10-2018 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 SUPERFAMILY SSF55021 3 76 7.55E-22 T 13-10-2018 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 4.3E-63 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 Pfam PF13710 ACT domain 13 74 1.6E-16 T 13-10-2018 Spica_2677 9f0187241c3502f7ce5d8abda473e0e1 166 Gene3D G3DSA:3.30.70.260 1 79 5.2E-35 T 13-10-2018 Spica_2456 14e40207e4be5f6f6f50c3823b02ce6c 532 Gene3D G3DSA:2.60.120.200 323 530 2.2E-44 T 13-10-2018 Spica_2456 14e40207e4be5f6f6f50c3823b02ce6c 532 SUPERFAMILY SSF75005 7 318 2.14E-94 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2456 14e40207e4be5f6f6f50c3823b02ce6c 532 Gene3D G3DSA:2.115.10.20 6 320 1.4E-95 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2456 14e40207e4be5f6f6f50c3823b02ce6c 532 Pfam PF04616 Glycosyl hydrolases family 43 7 298 4.9E-89 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spica_2456 14e40207e4be5f6f6f50c3823b02ce6c 532 SUPERFAMILY SSF49899 323 526 7.52E-45 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_1114 ef6636c7ac7affeba4dbbb075acea0d8 173 Pfam PF05130 FlgN protein 15 158 3.1E-8 T 13-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 Spica_1114 ef6636c7ac7affeba4dbbb075acea0d8 173 SUPERFAMILY SSF140566 17 142 2.75E-5 T 13-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 Spica_0487 239fab136480653e5a341f23f6f2ec90 170 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 164 3.4E-32 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Spica_0487 239fab136480653e5a341f23f6f2ec90 170 SUPERFAMILY SSF50447 3 86 2.12E-13 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0487 239fab136480653e5a341f23f6f2ec90 170 SUPERFAMILY SSF50346 97 164 4.19E-10 T 13-10-2018 IPR011033 PRC-barrel-like superfamily Spica_0487 239fab136480653e5a341f23f6f2ec90 170 Pfam PF05239 PRC-barrel domain 94 165 7.2E-6 T 13-10-2018 IPR027275 PRC-barrel domain Spica_0487 239fab136480653e5a341f23f6f2ec90 170 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 167 18.121 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Spica_0487 239fab136480653e5a341f23f6f2ec90 170 Gene3D G3DSA:2.40.30.60 5 89 4.0E-14 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 Spica_0487 239fab136480653e5a341f23f6f2ec90 170 Pfam PF01782 RimM N-terminal domain 7 86 4.6E-14 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 Spica_0487 239fab136480653e5a341f23f6f2ec90 170 Gene3D G3DSA:2.30.30.240 92 169 1.8E-9 T 13-10-2018 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 SUPERFAMILY SSF53756 2 390 1.1E-47 T 13-10-2018 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 Gene3D G3DSA:3.40.50.2000 1 191 9.9E-17 T 13-10-2018 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 Pfam PF01553 Acyltransferase 446 575 8.0E-19 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 Gene3D G3DSA:3.40.50.2000 219 381 3.8E-35 T 13-10-2018 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 SUPERFAMILY SSF69593 424 619 1.96E-20 T 13-10-2018 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 Pfam PF13439 Glycosyltransferase Family 4 15 181 1.4E-18 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 SMART SM00563 462 577 2.4E-17 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_2265 ef58720cb6d43abf64c97552cc8c4f81 631 Pfam PF00534 Glycosyl transferases group 1 222 367 9.5E-24 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_0997 ed54cb8ba0484badeb040fdf25f5b5a8 250 Gene3D G3DSA:3.20.20.370 20 246 1.2E-36 T 13-10-2018 Spica_0997 ed54cb8ba0484badeb040fdf25f5b5a8 250 Pfam PF01522 Polysaccharide deacetylase 75 203 1.9E-17 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spica_0997 ed54cb8ba0484badeb040fdf25f5b5a8 250 SUPERFAMILY SSF88713 43 234 3.21E-27 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Pfam PF00679 Elongation factor G C-terminus 593 679 1.7E-27 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Gene3D G3DSA:2.40.30.10 284 402 1.3E-31 T 13-10-2018 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Gene3D G3DSA:3.30.70.240 596 667 1.8E-85 T 13-10-2018 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Gene3D G3DSA:3.30.230.10 476 680 1.8E-85 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SUPERFAMILY SSF54980 397 473 2.81E-16 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Pfam PF14492 Elongation Factor G, domain II 396 469 2.0E-25 T 13-10-2018 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Gene3D G3DSA:3.40.50.300 4 280 1.8E-72 T 13-10-2018 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 159 7.1E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Pfam PF00009 Elongation factor Tu GTP binding domain 8 272 1.4E-36 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Gene3D G3DSA:3.30.70.870 403 475 1.9E-20 T 13-10-2018 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 Pfam PF03764 Elongation factor G, domain IV 471 590 2.5E-45 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SUPERFAMILY SSF54980 595 687 1.15E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SUPERFAMILY SSF50447 259 390 5.3E-25 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SMART SM00838 592 680 1.2E-30 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SMART SM00889 472 590 1.5E-67 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SUPERFAMILY SSF54211 471 591 2.38E-44 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1626 57676f6d627bb3238aefc7e390fef8f5 694 SUPERFAMILY SSF52540 4 275 7.53E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 SUPERFAMILY SSF55594 1 88 2.49E-28 T 13-10-2018 IPR035895 HPr-like superfamily Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.0E-18 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.0E-18 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.0E-18 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 3.2E-29 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 13-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.8E-30 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2578 4a2b4401b4afa81de0ee9483dea3f21b 88 Gene3D G3DSA:3.30.1340.10 1 85 8.7E-33 T 13-10-2018 IPR035895 HPr-like superfamily Spica_0029 693c5c5cc5c6b92db429831f90e82199 132 SUPERFAMILY SSF54637 1 123 5.56E-37 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_0029 693c5c5cc5c6b92db429831f90e82199 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 110 5.1E-21 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Spica_0029 693c5c5cc5c6b92db429831f90e82199 132 PIRSF PIRSF003230 1 125 4.6E-28 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Spica_0029 693c5c5cc5c6b92db429831f90e82199 132 Gene3D G3DSA:3.10.129.10 1 125 3.3E-37 T 13-10-2018 Spica_0029 693c5c5cc5c6b92db429831f90e82199 132 Pfam PF13279 Thioesterase-like superfamily 9 120 3.4E-15 T 13-10-2018 Spica_1687 27b0a1a7421eb69daaacc89080f9d8f1 96 Pfam PF04977 Septum formation initiator 18 79 5.8E-9 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC Spica_2332 521b37b3c644dc39f57ac301fded3588 343 SMART SM00740 120 192 7.5 T 13-10-2018 IPR005543 PASTA domain Spica_2332 521b37b3c644dc39f57ac301fded3588 343 SMART SM00740 197 264 2.5E-5 T 13-10-2018 IPR005543 PASTA domain Spica_2332 521b37b3c644dc39f57ac301fded3588 343 SMART SM00740 52 119 1.8E-10 T 13-10-2018 IPR005543 PASTA domain Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Gene3D G3DSA:3.30.10.20 51 121 7.4E-12 T 13-10-2018 Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Gene3D G3DSA:3.30.10.20 124 197 2.7E-5 T 13-10-2018 Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Gene3D G3DSA:3.30.10.20 198 264 2.6E-7 T 13-10-2018 Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Pfam PF03793 PASTA domain 58 118 7.4E-10 T 13-10-2018 IPR005543 PASTA domain Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Pfam PF03793 PASTA domain 125 183 6.6E-5 T 13-10-2018 IPR005543 PASTA domain Spica_2332 521b37b3c644dc39f57ac301fded3588 343 Pfam PF03793 PASTA domain 201 262 5.6E-7 T 13-10-2018 IPR005543 PASTA domain Spica_0015 853424f88aa781867a6c08f87b61bc5a 265 Pfam PF00588 SpoU rRNA Methylase family 121 254 2.2E-26 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spica_0015 853424f88aa781867a6c08f87b61bc5a 265 Gene3D G3DSA:3.40.1280.10 122 261 2.3E-32 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0015 853424f88aa781867a6c08f87b61bc5a 265 SUPERFAMILY SSF75217 114 258 1.5E-28 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0223 38d9e126e272685816ec598979ac1cf5 305 SUPERFAMILY SSF103481 40 143 5.23E-12 T 13-10-2018 Spica_0223 38d9e126e272685816ec598979ac1cf5 305 SUPERFAMILY SSF103481 191 295 2.09E-18 T 13-10-2018 Spica_0223 38d9e126e272685816ec598979ac1cf5 305 Pfam PF00892 EamA-like transporter family 157 291 6.2E-26 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_0223 38d9e126e272685816ec598979ac1cf5 305 Pfam PF00892 EamA-like transporter family 6 140 5.1E-24 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 Gene3D G3DSA:1.20.58.930 363 453 8.3E-214 T 13-10-2018 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 SUPERFAMILY SSF50621 443 562 5.75E-7 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PIRSF PIRSF001336 1 635 2.9E-238 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 Gene3D G3DSA:2.40.37.10 12 562 8.3E-214 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 274 287 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 95 113 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 Gene3D G3DSA:3.20.20.10 64 345 8.3E-214 T 13-10-2018 IPR029066 PLP-binding barrel Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 119 131 9.6E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 236 249 9.6E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 113 9.6E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 537 550 9.6E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 330 349 9.6E-19 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 73 340 1.3E-43 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 320 337 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 143 158 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 63 78 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 87 101 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 169 190 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 457 478 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 193 215 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 482 507 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 PRINTS PR01180 Arginine decarboxylase signature 537 558 8.0E-71 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 TIGRFAM TIGR01273 speA: arginine decarboxylase 3 633 1.7E-218 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 Spica_1595 c05c900451a44f235f8616a4cdc64e21 640 SUPERFAMILY SSF51419 64 343 9.16E-67 T 13-10-2018 IPR029066 PLP-binding barrel Spica_0467 15a43ec194cf2a980598183e81f75f61 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.165 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 13-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 1.0E-62 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 PIRSF PIRSF002181 1 141 2.2E-48 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 Gene3D G3DSA:3.90.1180.10 1 142 4.6E-61 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 Pfam PF00572 Ribosomal protein L13 14 138 1.4E-53 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Spica_0467 15a43ec194cf2a980598183e81f75f61 142 SUPERFAMILY SSF52161 1 140 1.7E-56 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SUPERFAMILY SSF158832 17 325 6.41E-97 T 13-10-2018 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SUPERFAMILY SSF53098 327 469 9.86E-45 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SUPERFAMILY SSF50249 629 716 6.34E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SMART SM00316 643 714 1.1E-24 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SUPERFAMILY SSF47781 562 625 1.0E-12 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Gene3D G3DSA:1.10.3500.10 125 499 1.1E-136 T 13-10-2018 IPR023323 Tex-like domain superfamily Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Pfam PF00575 S1 RNA binding domain 644 714 1.3E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SUPERFAMILY SSF47781 471 559 1.01E-26 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Gene3D G3DSA:3.30.420.140 330 452 1.1E-136 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Gene3D G3DSA:2.40.50.140 627 719 3.0E-24 T 13-10-2018 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Gene3D G3DSA:1.10.150.310 500 624 2.2E-42 T 13-10-2018 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Pfam PF09371 Tex-like protein N-terminal domain 22 209 2.8E-63 T 13-10-2018 IPR018974 Tex-like protein, N-terminal Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 SMART SM00732 331 425 3.3E-27 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Pfam PF12836 Helix-hairpin-helix motif 492 555 6.2E-27 T 13-10-2018 Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Pfam PF16921 Tex protein YqgF-like domain 332 452 9.6E-45 T 13-10-2018 IPR032639 Tex protein, YqgF-like domain Spica_2405 1466c648acbeea6bd83bc8f00b4c37fe 819 Gene3D G3DSA:1.10.10.650 12 122 5.4E-35 T 13-10-2018 IPR023319 Tex-like protein, HTH domain superfamily Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 SUPERFAMILY SSF51206 12 141 8.51E-33 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 Pfam PF00027 Cyclic nucleotide-binding domain 39 125 2.8E-22 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 Gene3D G3DSA:3.30.70.270 160 336 4.6E-49 T 13-10-2018 Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 SMART SM00267 149 336 1.7E-44 T 13-10-2018 IPR000160 GGDEF domain Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 Pfam PF00990 Diguanylate cyclase, GGDEF domain 166 332 5.1E-41 T 13-10-2018 IPR000160 GGDEF domain Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 165 335 1.5E-42 T 13-10-2018 IPR000160 GGDEF domain Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 Gene3D G3DSA:2.60.120.10 11 156 2.0E-35 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 PRINTS PR00103 cAMP-dependent protein kinase signature 130 142 1.6E-5 T 13-10-2018 Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 PRINTS PR00103 cAMP-dependent protein kinase signature 86 95 1.6E-5 T 13-10-2018 Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 PRINTS PR00103 cAMP-dependent protein kinase signature 41 55 1.6E-5 T 13-10-2018 Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 PRINTS PR00103 cAMP-dependent protein kinase signature 98 109 1.6E-5 T 13-10-2018 Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 SMART SM00100 20 138 3.3E-20 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_2521 4a79eab69910e12bd93cdc8dc43d547b 337 SUPERFAMILY SSF55073 171 334 2.12E-41 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0559 962c1fae4e266918b445ed906f0abc03 301 Pfam PF07650 KH domain 210 288 1.8E-18 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 169 7.1E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 Hamap MF_00367 GTPase Era [era]. 3 299 31.221 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 282 3.4E-74 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 SUPERFAMILY SSF52540 8 216 6.83E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0559 962c1fae4e266918b445ed906f0abc03 301 SMART SM00382 4 127 2.7E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0559 962c1fae4e266918b445ed906f0abc03 301 Gene3D G3DSA:3.40.50.300 2 187 5.1E-40 T 13-10-2018 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 Pfam PF01926 50S ribosome-binding GTPase 8 125 2.1E-21 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0559 962c1fae4e266918b445ed906f0abc03 301 Gene3D G3DSA:3.30.300.20 188 299 1.8E-36 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_0559 962c1fae4e266918b445ed906f0abc03 301 SUPERFAMILY SSF54814 184 297 1.57E-34 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Spica_2340 08f58d521395a47ccaccb12b56805849 274 SMART SM00138 9 272 2.9E-71 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 Gene3D G3DSA:3.40.50.150 77 272 5.8E-58 T 13-10-2018 Spica_2340 08f58d521395a47ccaccb12b56805849 274 SUPERFAMILY SSF53335 78 270 2.24E-46 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2340 08f58d521395a47ccaccb12b56805849 274 Pfam PF01739 CheR methyltransferase, SAM binding domain 78 266 2.8E-54 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_2340 08f58d521395a47ccaccb12b56805849 274 PIRSF PIRSF000410 3 273 4.4E-76 T 13-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 71 83 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 142 158 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 PRINTS PR00996 Glutamate methyltransferase family signature 31 44 6.9E-37 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Spica_2340 08f58d521395a47ccaccb12b56805849 274 Gene3D G3DSA:1.10.155.10 2 76 9.7E-9 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_2340 08f58d521395a47ccaccb12b56805849 274 SUPERFAMILY SSF47757 6 77 1.31E-9 T 13-10-2018 Spica_2340 08f58d521395a47ccaccb12b56805849 274 Pfam PF03705 CheR methyltransferase, all-alpha domain 12 63 1.9E-9 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_0152 572e505aed5f7f140ea7df774a3943c0 311 Pfam PF01458 Uncharacterized protein family (UPF0051) 91 308 1.8E-32 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Spica_0152 572e505aed5f7f140ea7df774a3943c0 311 SUPERFAMILY SSF101960 57 310 8.24E-43 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 9 478 8.7E-232 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 Gene3D G3DSA:1.10.1040.10 186 443 1.6E-107 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 SUPERFAMILY SSF51735 8 178 3.44E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 254 281 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 173 201 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 8 31 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 365 387 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 124 149 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 71 100 1.2E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 Gene3D G3DSA:1.20.5.320 444 491 1.6E-25 T 13-10-2018 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 169 2.6E-52 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 258 270 - T 13-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 SMART SM01350 184 478 3.1E-216 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 184 477 4.5E-129 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 PIRSF PIRSF000109 3 486 1.1E-238 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 Gene3D G3DSA:3.40.50.720 1 185 3.4E-54 T 13-10-2018 Spica_2625 00b258e93a495ad8226a272ae1163b6d 491 SUPERFAMILY SSF48179 182 481 1.64E-129 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 Gene3D G3DSA:2.40.30.130 1 92 1.1E-20 T 13-10-2018 Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 SUPERFAMILY SSF55186 112 254 5.23E-29 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 Gene3D G3DSA:3.30.980.10 109 263 2.7E-38 T 13-10-2018 Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 205 246 6.5E-7 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 SUPERFAMILY SSF50447 2 68 4.59E-14 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0187 fec33fb4ed1997cde337b59e3d7f2e86 416 SMART SM00863 205 247 3.6E-8 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 Gene3D G3DSA:2.40.30.10 300 368 4.1E-12 T 13-10-2018 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 Gene3D G3DSA:2.30.30.280 239 299 6.0E-20 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 22 365 3.7E-87 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 SUPERFAMILY SSF52402 22 268 2.18E-42 T 13-10-2018 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 20 402 33.368 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 Pfam PF03054 tRNA methyl transferase 22 366 2.0E-93 T 13-10-2018 Spica_1040 1c8c85bc4f102af770d99e5289baf6b0 409 Gene3D G3DSA:3.40.50.620 8 236 1.1E-61 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1879 74dbc5378381ef1d68b19d8cc0b74b35 107 SUPERFAMILY SSF143011 1 76 1.57E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1879 74dbc5378381ef1d68b19d8cc0b74b35 107 Gene3D G3DSA:3.30.2310.20 1 105 7.2E-17 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Gene3D G3DSA:1.10.10.10 188 264 1.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 SUPERFAMILY SSF88659 246 337 2.62E-23 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Pfam PF00140 Sigma-70 factor, region 1.2 47 75 1.0E-8 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Pfam PF04542 Sigma-70 region 2 115 184 1.8E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Pfam PF04545 Sigma-70, region 4 283 336 1.1E-16 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Gene3D G3DSA:1.10.601.10 63 184 1.8E-43 T 13-10-2018 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Gene3D G3DSA:1.10.10.10 265 346 3.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 PRINTS PR00046 Major sigma-70 factor signature 323 334 3.5E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 PRINTS PR00046 Major sigma-70 factor signature 287 299 3.5E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 PRINTS PR00046 Major sigma-70 factor signature 308 323 3.5E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 PRINTS PR00046 Major sigma-70 factor signature 163 171 3.5E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 PRINTS PR00046 Major sigma-70 factor signature 139 152 3.5E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 113 336 1.3E-33 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 SUPERFAMILY SSF88946 47 185 6.59E-44 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 308 334 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 Pfam PF04539 Sigma-70 region 3 200 270 1.9E-18 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Spica_1027 49135bb19f300722e7bf39cde1bdc661 346 SUPERFAMILY SSF88659 188 262 6.54E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_2458 4d7bb90f709ce90fcd63097b55e6d055 299 Gene3D G3DSA:3.40.50.1820 59 298 1.4E-48 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2458 4d7bb90f709ce90fcd63097b55e6d055 299 Pfam PF07859 alpha/beta hydrolase fold 102 195 1.5E-5 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Spica_2458 4d7bb90f709ce90fcd63097b55e6d055 299 Pfam PF00326 Prolyl oligopeptidase family 230 279 1.1E-7 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Spica_2458 4d7bb90f709ce90fcd63097b55e6d055 299 SUPERFAMILY SSF53474 47 297 1.11E-27 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 Gene3D G3DSA:1.10.10.2830 110 224 6.9E-39 T 13-10-2018 Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 Pfam PF02195 ParB-like nuclease domain 35 122 1.3E-27 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 30 200 5.3E-57 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 Gene3D G3DSA:3.90.1530.30 46 108 6.6E-28 T 13-10-2018 Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 SUPERFAMILY SSF110849 35 169 7.32E-35 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Spica_2788 890c393d2c5de8cbe05be2c3eab1e52e 297 SMART SM00470 33 123 1.1E-37 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 Gene3D G3DSA:3.30.830.10 2 211 1.9E-49 T 13-10-2018 Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 Pfam PF00675 Insulinase (Peptidase family M16) 14 158 1.5E-27 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 Gene3D G3DSA:3.30.830.10 230 415 3.2E-39 T 13-10-2018 Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 Pfam PF05193 Peptidase M16 inactive domain 167 337 3.2E-25 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 SUPERFAMILY SSF63411 5 205 8.38E-48 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 Spica_1359 9e9a555bb8637789cc8e60faed9ae3c1 433 SUPERFAMILY SSF63411 233 409 2.55E-34 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 5.4E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.0E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.0E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.0E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 SMART SM00421 150 207 3.4E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 SMART SM00448 5 118 2.4E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 Pfam PF00072 Response regulator receiver domain 8 119 2.3E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 SUPERFAMILY SSF52172 8 136 2.56E-27 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 Gene3D G3DSA:3.40.50.12740 7 210 6.9E-51 T 13-10-2018 Spica_0308 f2f64df71760fc7127fe992dfd008c67 216 SUPERFAMILY SSF46894 145 209 1.36E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_1499 ba2c84a912dd0bd51e34cff09fc357cc 141 SUPERFAMILY SSF81333 77 137 7.98E-8 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Spica_1499 ba2c84a912dd0bd51e34cff09fc357cc 141 Pfam PF00137 ATP synthase subunit C 80 137 5.0E-8 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Spica_1499 ba2c84a912dd0bd51e34cff09fc357cc 141 Gene3D G3DSA:1.20.120.610 1 140 2.0E-13 T 13-10-2018 Spica_2795 5414a370deb61a58ea566da10d43a9cc 587 Pfam PF07510 Protein of unknown function (DUF1524) 445 571 8.7E-9 T 13-10-2018 IPR011089 Domain of unknown function DUF1524 Spica_2795 5414a370deb61a58ea566da10d43a9cc 587 Pfam PF03235 Protein of unknown function DUF262 8 212 1.7E-32 T 13-10-2018 IPR004919 Domain of unknown function DUF262 Spica_2320 b673640d92c6af6b151e23a0a445977d 324 Gene3D G3DSA:3.40.50.2300 36 295 5.7E-88 T 13-10-2018 Spica_2320 b673640d92c6af6b151e23a0a445977d 324 Gene3D G3DSA:3.40.50.2300 137 279 5.7E-88 T 13-10-2018 Spica_2320 b673640d92c6af6b151e23a0a445977d 324 SUPERFAMILY SSF53822 31 306 9.62E-60 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2320 b673640d92c6af6b151e23a0a445977d 324 Pfam PF13407 Periplasmic binding protein domain 44 298 4.0E-41 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2633 e39263252185b6600918c634b7e4afc5 462 Gene3D G3DSA:3.30.450.20 43 135 3.7E-14 T 13-10-2018 Spica_2633 e39263252185b6600918c634b7e4afc5 462 SUPERFAMILY SSF55785 47 134 1.7E-11 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2633 e39263252185b6600918c634b7e4afc5 462 SMART SM00267 292 461 8.5E-50 T 13-10-2018 IPR000160 GGDEF domain Spica_2633 e39263252185b6600918c634b7e4afc5 462 SUPERFAMILY SSF55073 308 462 7.14E-45 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2633 e39263252185b6600918c634b7e4afc5 462 Pfam PF08447 PAS fold 51 126 1.6E-11 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Spica_2633 e39263252185b6600918c634b7e4afc5 462 SUPERFAMILY SSF55781 158 296 9.6E-15 T 13-10-2018 Spica_2633 e39263252185b6600918c634b7e4afc5 462 Pfam PF00990 Diguanylate cyclase, GGDEF domain 303 457 2.2E-42 T 13-10-2018 IPR000160 GGDEF domain Spica_2633 e39263252185b6600918c634b7e4afc5 462 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 300 459 7.1E-46 T 13-10-2018 IPR000160 GGDEF domain Spica_2633 e39263252185b6600918c634b7e4afc5 462 Gene3D G3DSA:3.30.70.270 303 462 1.3E-51 T 13-10-2018 Spica_2633 e39263252185b6600918c634b7e4afc5 462 Gene3D G3DSA:3.30.450.40 149 302 2.0E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 289 37.116 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 Pfam PF05175 Methyltransferase small domain 109 212 2.1E-14 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 SUPERFAMILY SSF53335 6 285 2.94E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 Gene3D G3DSA:1.10.8.10 4 85 7.1E-19 T 13-10-2018 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 Gene3D G3DSA:3.40.50.150 86 290 5.3E-55 T 13-10-2018 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 285 3.8E-77 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 287 3.2E-64 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Spica_0420 b3e12d0e8d16ce50e2e426cd2f0c5227 292 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_2162 c1d29e5a6099de04a542824311538414 230 Pfam PF04256 Protein of unknown function (DUF434) 8 62 1.1E-17 T 13-10-2018 IPR007368 Protein of unknown function DUF434 Spica_2162 c1d29e5a6099de04a542824311538414 230 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 8 61 9.0E-5 T 13-10-2018 IPR007368 Protein of unknown function DUF434 Spica_0870 227815fb4a0a014242767830b324b061 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 106 4.0E-29 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Spica_0715 2312ebd47b0edaf28636473a2f7752c3 281 SUPERFAMILY SSF161098 11 281 3.79E-64 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0715 2312ebd47b0edaf28636473a2f7752c3 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 265 2.4E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0715 2312ebd47b0edaf28636473a2f7752c3 281 Gene3D G3DSA:1.10.3720.10 2 268 4.7E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1601 a411da3ee3e0dc609ada803592ba8aa0 345 Gene3D G3DSA:3.40.50.150 108 345 2.9E-66 T 13-10-2018 Spica_1601 a411da3ee3e0dc609ada803592ba8aa0 345 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 125 303 2.1E-22 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Spica_1601 a411da3ee3e0dc609ada803592ba8aa0 345 Gene3D G3DSA:3.30.750.80 13 104 1.4E-24 T 13-10-2018 Spica_1601 a411da3ee3e0dc609ada803592ba8aa0 345 SUPERFAMILY SSF53335 17 316 5.63E-58 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0819 74d163a2e13084350612c6f1d250d23a 290 Gene3D G3DSA:3.40.1190.20 1 290 6.0E-78 T 13-10-2018 IPR029056 Ribokinase-like Spica_0819 74d163a2e13084350612c6f1d250d23a 290 SUPERFAMILY SSF53613 2 289 4.37E-68 T 13-10-2018 IPR029056 Ribokinase-like Spica_0819 74d163a2e13084350612c6f1d250d23a 290 PRINTS PR00990 Ribokinase signature 32 51 1.2E-22 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Spica_0819 74d163a2e13084350612c6f1d250d23a 290 PRINTS PR00990 Ribokinase signature 168 183 1.2E-22 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Spica_0819 74d163a2e13084350612c6f1d250d23a 290 PRINTS PR00990 Ribokinase signature 5 26 1.2E-22 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Spica_0819 74d163a2e13084350612c6f1d250d23a 290 PRINTS PR00990 Ribokinase signature 101 114 1.2E-22 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Spica_0819 74d163a2e13084350612c6f1d250d23a 290 PRINTS PR00990 Ribokinase signature 208 219 1.2E-22 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Spica_0819 74d163a2e13084350612c6f1d250d23a 290 Pfam PF00294 pfkB family carbohydrate kinase 6 285 1.7E-45 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 140 167 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 306 6.1E-20 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 Gene3D G3DSA:3.40.50.720 22 303 3.5E-77 T 13-10-2018 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 Gene3D G3DSA:3.30.70.260 308 387 4.1E-18 T 13-10-2018 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 SUPERFAMILY SSF52283 20 105 3.4E-20 T 13-10-2018 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 SUPERFAMILY SSF51735 86 275 2.94E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 125 274 4.1E-43 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 Gene3D G3DSA:3.40.50.720 84 278 3.5E-77 T 13-10-2018 Spica_2574 34ef1bfca6e41c37deade7889392b69f 389 SUPERFAMILY SSF55021 313 387 5.34E-14 T 13-10-2018 Spica_0409 334e63fff9fbeca26f997cc854404636 211 SMART SM01390 3 98 7.6E-43 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Spica_0409 334e63fff9fbeca26f997cc854404636 211 ProSitePatterns PS00632 Ribosomal protein S4 signature. 97 121 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0409 334e63fff9fbeca26f997cc854404636 211 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 98 5.1E-26 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Spica_0409 334e63fff9fbeca26f997cc854404636 211 Gene3D G3DSA:3.10.290.10 98 194 2.9E-79 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_0409 334e63fff9fbeca26f997cc854404636 211 Gene3D G3DSA:1.10.1050.10 6 211 2.9E-79 T 13-10-2018 Spica_0409 334e63fff9fbeca26f997cc854404636 211 Pfam PF01479 S4 domain 99 146 1.6E-21 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0409 334e63fff9fbeca26f997cc854404636 211 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 211 2.3E-64 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spica_0409 334e63fff9fbeca26f997cc854404636 211 SMART SM00363 99 163 9.9E-22 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0409 334e63fff9fbeca26f997cc854404636 211 SUPERFAMILY SSF55174 3 211 3.4E-61 T 13-10-2018 Spica_0409 334e63fff9fbeca26f997cc854404636 211 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 211 33.057 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 SUPERFAMILY SSF51735 222 384 3.11E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Gene3D G3DSA:3.30.70.1450 131 218 1.6E-15 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 SUPERFAMILY SSF51735 2 138 1.93E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 SUPERFAMILY SSF116726 371 456 2.49E-12 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Gene3D G3DSA:3.40.50.720 1 128 5.6E-34 T 13-10-2018 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Pfam PF02254 TrkA-N domain 225 356 6.3E-21 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Pfam PF02254 TrkA-N domain 2 114 2.6E-21 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 SUPERFAMILY SSF116726 130 213 4.45E-11 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Pfam PF02080 TrkA-C domain 147 212 3.2E-12 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Pfam PF02080 TrkA-C domain 389 456 2.1E-10 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Gene3D G3DSA:3.40.50.720 221 371 4.5E-30 T 13-10-2018 Spica_2515 09aba7478bcafb5fa18a3bb41876b799 459 Gene3D G3DSA:3.30.70.1450 375 458 9.4E-17 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_1374 15ed372fb4afa2db92b2cbc73d6f8f82 172 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 138 7.4E-31 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Spica_1374 15ed372fb4afa2db92b2cbc73d6f8f82 172 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 138 6.0E-31 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Spica_1374 15ed372fb4afa2db92b2cbc73d6f8f82 172 SUPERFAMILY SSF55083 7 162 8.76E-41 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Spica_1374 15ed372fb4afa2db92b2cbc73d6f8f82 172 Gene3D G3DSA:3.30.70.560 5 166 8.3E-42 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 8.8E-64 T 13-10-2018 IPR023798 Ribosomal protein S7 domain Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.523 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.2E-69 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 PIRSF PIRSF002122 3 156 1.9E-60 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 Gene3D G3DSA:1.10.455.10 2 156 1.0E-63 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Spica_0382 dfb4db4882effc1c0a4aab7a5723ddba 156 SUPERFAMILY SSF47973 11 149 1.57E-60 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Spica_0041 f60c4b1df2958da8a995d3abc7f4835e 134 Pfam PF04519 Polymer-forming cytoskeletal 13 109 6.5E-20 T 13-10-2018 IPR007607 Bactofilin A/B Spica_0041 f60c4b1df2958da8a995d3abc7f4835e 134 SUPERFAMILY SSF51161 12 112 2.88E-5 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_0864 6d3f6f4f1c488bbd8a1bf4da33bfd6a9 151 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 53 69 - T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_0864 6d3f6f4f1c488bbd8a1bf4da33bfd6a9 151 Gene3D G3DSA:3.40.930.10 1 151 2.0E-48 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_0864 6d3f6f4f1c488bbd8a1bf4da33bfd6a9 151 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 8 133 1.0E-34 T 13-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 Spica_0864 6d3f6f4f1c488bbd8a1bf4da33bfd6a9 151 SUPERFAMILY SSF55804 4 148 5.62E-41 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_0864 6d3f6f4f1c488bbd8a1bf4da33bfd6a9 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 148 2.6E-42 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 Gene3D G3DSA:1.10.287.70 9 242 3.0E-17 T 13-10-2018 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 Pfam PF00520 Ion transport protein 12 242 1.6E-14 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 Gene3D G3DSA:1.10.287.630 243 304 2.2E-21 T 13-10-2018 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 345 361 - T 13-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 SMART SM00100 318 434 3.7E-18 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 PRINTS PR01463 EAG/ELK/ERG potassium channel family signature 185 202 4.2E-5 T 13-10-2018 IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG GO:0005249|GO:0006813|GO:0016020 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 PRINTS PR01463 EAG/ELK/ERG potassium channel family signature 231 240 4.2E-5 T 13-10-2018 IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG GO:0005249|GO:0006813|GO:0016020 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 PRINTS PR01463 EAG/ELK/ERG potassium channel family signature 55 64 4.2E-5 T 13-10-2018 IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG GO:0005249|GO:0006813|GO:0016020 Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 Pfam PF00027 Cyclic nucleotide-binding domain 338 419 4.0E-19 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 SUPERFAMILY SSF51206 246 433 1.31E-48 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 Gene3D G3DSA:2.60.120.10 305 430 4.5E-36 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0293 5879cc401ddfa988ed43d1117de9e4fc 436 SUPERFAMILY SSF81324 6 239 2.75E-28 T 13-10-2018 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 SUPERFAMILY SSF55205 17 464 8.76E-102 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 22 469 29.285 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 ProSitePatterns PS00885 EPSP synthase signature 2. 380 398 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 Gene3D G3DSA:3.65.10.10 25 463 2.3E-117 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 27 463 3.1E-106 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 117 462 7.1E-83 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 21 93 2.5E-11 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 Gene3D G3DSA:3.65.10.10 34 276 2.3E-117 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Spica_2514 056dafdce5b05e173944aa0fc86931f7 469 PIRSF PIRSF000505 13 467 1.2E-113 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Spica_0476 5e7b562c39676400aeee15f5e3600545 106 Gene3D G3DSA:3.30.750.24 4 104 3.7E-19 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0476 5e7b562c39676400aeee15f5e3600545 106 SUPERFAMILY SSF52091 12 100 8.04E-19 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0476 5e7b562c39676400aeee15f5e3600545 106 Pfam PF01740 STAS domain 14 99 3.0E-14 T 13-10-2018 IPR002645 STAS domain Spica_0900 a38fe4276bef7ad790e675775e707315 104 SUPERFAMILY SSF69118 3 76 1.44E-5 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Spica_0900 a38fe4276bef7ad790e675775e707315 104 Gene3D G3DSA:1.20.1290.10 8 88 1.1E-5 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 PRINTS PR00110 Alpha-amylase signature 124 135 3.1E-6 T 13-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 PRINTS PR00110 Alpha-amylase signature 329 341 3.1E-6 T 13-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 PRINTS PR00110 Alpha-amylase signature 222 233 3.1E-6 T 13-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 Gene3D G3DSA:3.20.20.80 37 473 2.5E-121 T 13-10-2018 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 SUPERFAMILY SSF51445 27 478 1.12E-99 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 Pfam PF00128 Alpha amylase, catalytic domain 53 408 4.2E-71 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 SMART SM00642 38 444 1.6E-101 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0086 7b0c31184eccc277dadba012dd39b9c5 569 Gene3D G3DSA:3.90.400.10 143 208 2.5E-121 T 13-10-2018 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PIRSF PIRSF003161 21 356 4.8E-122 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Gene3D G3DSA:1.10.220.30 125 216 5.3E-35 T 13-10-2018 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Gene3D G3DSA:1.10.220.30 20 107 1.1E-20 T 13-10-2018 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Pfam PF01706 FliG C-terminal domain 239 345 1.3E-44 T 13-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 SUPERFAMILY SSF48029 28 134 2.62E-21 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Pfam PF14841 FliG middle domain 137 211 1.0E-31 T 13-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 56 82 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 136 159 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 27 43 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 248 268 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 270 290 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 294 320 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 PRINTS PR00954 Flagellar motor switch protein FliG signature 217 242 6.8E-87 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 SUPERFAMILY SSF48029 136 346 2.88E-70 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Gene3D G3DSA:1.10.220.30 217 356 3.6E-52 T 13-10-2018 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 22 355 4.3E-150 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1669 3a1ddef7a2639f16ab597a500e107051 356 Pfam PF14842 FliG N-terminal domain 26 129 1.7E-35 T 13-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.5E-45 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.5E-22 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 Gene3D G3DSA:3.40.5.10 1 61 3.9E-24 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 3.6E-24 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 Gene3D G3DSA:3.10.430.100 62 148 5.3E-24 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 SUPERFAMILY SSF55658 1 57 1.33E-18 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 SUPERFAMILY SSF55653 60 147 1.28E-23 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1425 1b49ebf03d758f79fe97db3ddd2bdce9 192 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.122 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 Gene3D G3DSA:3.40.50.170 1 219 4.9E-64 T 13-10-2018 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 SUPERFAMILY SSF53328 1 220 2.88E-50 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 330 2.1E-75 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 Gene3D G3DSA:3.10.25.10 220 332 3.7E-26 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 327 27.871 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 Pfam PF02911 Formyl transferase, C-terminal domain 218 324 1.3E-23 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 Pfam PF00551 Formyl transferase 1 193 1.9E-31 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2333 eaa8f6eb17a873204292ca1d2b2def1b 333 SUPERFAMILY SSF50486 218 332 8.83E-25 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 Spica_0096 c70ca87105a4c728d7472d39847cede1 70 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 51 1.0E-7 T 13-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Spica_0096 c70ca87105a4c728d7472d39847cede1 70 Gene3D G3DSA:3.30.160.250 1 68 4.9E-17 T 13-10-2018 Spica_0096 c70ca87105a4c728d7472d39847cede1 70 SUPERFAMILY SSF143100 1 55 6.54E-17 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like Spica_1032 35fefe87475b6edf2aa330392e5ede80 462 PIRSF PIRSF015658 74 461 9.9E-174 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 Spica_1032 35fefe87475b6edf2aa330392e5ede80 462 PIRSF PIRSF015658 7 34 460.0 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 Spica_1032 35fefe87475b6edf2aa330392e5ede80 462 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 104 459 4.8E-152 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 Spica_1032 35fefe87475b6edf2aa330392e5ede80 462 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 105 455 1.3E-168 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 Spica_0669 8192579405ac72b50817881408b990eb 310 SUPERFAMILY SSF56176 11 194 6.18E-29 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Spica_0669 8192579405ac72b50817881408b990eb 310 SUPERFAMILY SSF56194 200 303 1.83E-28 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0669 8192579405ac72b50817881408b990eb 310 Gene3D G3DSA:3.30.43.10 2 86 7.0E-24 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Spica_0669 8192579405ac72b50817881408b990eb 310 Gene3D G3DSA:3.30.465.10 90 215 1.0E-26 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_0669 8192579405ac72b50817881408b990eb 310 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 301 3.8E-62 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0669 8192579405ac72b50817881408b990eb 310 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 310 66.333 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0669 8192579405ac72b50817881408b990eb 310 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 300 3.5E-22 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0669 8192579405ac72b50817881408b990eb 310 Pfam PF01565 FAD binding domain 50 146 7.5E-12 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Spica_0669 8192579405ac72b50817881408b990eb 310 Gene3D G3DSA:3.90.78.10 217 309 3.1E-26 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_2273 b1fba9316640802ad5b576d708f50450 510 Pfam PF00005 ABC transporter 360 437 6.5E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2273 b1fba9316640802ad5b576d708f50450 510 Pfam PF00664 ABC transporter transmembrane region 26 294 3.1E-39 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_2273 b1fba9316640802ad5b576d708f50450 510 Gene3D G3DSA:3.40.50.300 444 510 4.1E-19 T 13-10-2018 Spica_2273 b1fba9316640802ad5b576d708f50450 510 ProSitePatterns PS00211 ABC transporters family signature. 449 463 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2273 b1fba9316640802ad5b576d708f50450 510 SUPERFAMILY SSF90123 12 330 2.35E-65 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2273 b1fba9316640802ad5b576d708f50450 510 SMART SM00382 369 509 1.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2273 b1fba9316640802ad5b576d708f50450 510 Pfam PF00005 ABC transporter 445 477 9.7E-6 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2273 b1fba9316640802ad5b576d708f50450 510 Gene3D G3DSA:1.20.1560.10 2 330 4.4E-69 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2273 b1fba9316640802ad5b576d708f50450 510 Gene3D G3DSA:3.40.50.300 337 443 5.6E-34 T 13-10-2018 Spica_2273 b1fba9316640802ad5b576d708f50450 510 SUPERFAMILY SSF52540 337 510 8.25E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2859 ef94e5b29420ccc13f08af03a727c5be 144 SUPERFAMILY SSF110916 15 98 3.27E-15 T 13-10-2018 Spica_2859 ef94e5b29420ccc13f08af03a727c5be 144 Pfam PF00472 RF-1 domain 12 128 2.4E-18 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Spica_2859 ef94e5b29420ccc13f08af03a727c5be 144 Gene3D G3DSA:3.30.160.20 8 137 1.3E-34 T 13-10-2018 Spica_1957 51a0f1ac6908668b2336a0b859a86a67 326 SUPERFAMILY SSF51395 2 304 2.25E-49 T 13-10-2018 Spica_1957 51a0f1ac6908668b2336a0b859a86a67 326 Gene3D G3DSA:3.20.20.70 4 292 3.3E-56 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1957 51a0f1ac6908668b2336a0b859a86a67 326 Pfam PF01180 Dihydroorotate dehydrogenase 4 288 9.1E-17 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Spica_1957 51a0f1ac6908668b2336a0b859a86a67 326 PIRSF PIRSF000164 1 305 5.8E-31 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 SUPERFAMILY SSF56784 1 204 9.24E-31 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 169 2.5E-13 T 13-10-2018 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 Gene3D G3DSA:1.10.150.450 15 84 3.1E-25 T 13-10-2018 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 Gene3D G3DSA:3.40.50.1000 5 204 3.1E-25 T 13-10-2018 IPR023214 HAD superfamily Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.6E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 4.6E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 4.6E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_2712 190fdd21fe62168e5223c7452816bdc0 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 6 183 1.0E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 Gene3D G3DSA:3.50.50.60 6 303 1.2E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 2.3E-33 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 275 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 308 9.1E-21 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 Gene3D G3DSA:3.50.50.60 127 260 1.2E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 SUPERFAMILY SSF51905 1 329 2.44E-40 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.8E-20 T 13-10-2018 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 8.8E-20 T 13-10-2018 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 8.8E-20 T 13-10-2018 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 8.8E-20 T 13-10-2018 Spica_2722 bad733180188c88adfc1a7e8d25d3ec4 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 8.8E-20 T 13-10-2018 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 30.932 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 Gene3D G3DSA:3.40.1010.20 100 199 1.6E-86 T 13-10-2018 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 Pfam PF02401 LytB protein 4 284 1.5E-84 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 Gene3D G3DSA:3.40.50.11270 12 99 1.6E-86 T 13-10-2018 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 Gene3D G3DSA:3.40.1010.20 5 283 1.6E-86 T 13-10-2018 Spica_1830 613aa0cceb9e85087c32d69bec5f5d1c 289 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 4 286 2.2E-81 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 Gene3D G3DSA:3.30.450.20 31 225 2.6E-20 T 13-10-2018 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 SUPERFAMILY SSF58104 377 693 7.46E-49 T 13-10-2018 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 SMART SM00304 355 409 4.2E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 Gene3D G3DSA:1.10.287.950 477 695 3.5E-44 T 13-10-2018 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 SMART SM00283 452 699 8.4E-51 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 Pfam PF02743 Cache domain 33 305 4.7E-27 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 519 667 1.7E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2399 19e9fe82a1c7567fc3c8bfdb68d80861 742 Gene3D G3DSA:1.10.287.950 356 476 4.7E-11 T 13-10-2018 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 Gene3D G3DSA:3.90.550.10 1 290 3.2E-88 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 SUPERFAMILY SSF53448 3 387 1.13E-71 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 10 29 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 4 389 7.2E-135 T 13-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 Pfam PF00483 Nucleotidyl transferase 6 270 2.7E-58 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 Gene3D G3DSA:2.160.10.10 291 424 1.7E-38 T 13-10-2018 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 SUPERFAMILY SSF51161 296 424 1.23E-18 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 96 104 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Spica_1248 91071eea4d9187806fbb19e712d58d6a 424 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 207 217 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 Gene3D G3DSA:1.10.10.60 171 223 6.3E-13 T 13-10-2018 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 SUPERFAMILY SSF51215 22 150 2.09E-10 T 13-10-2018 IPR037923 Transcription regulator HTH-like Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 SUPERFAMILY SSF46689 227 277 1.88E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 273 6.6E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 242 257 6.6E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 SUPERFAMILY SSF46689 173 224 2.37E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 227 269 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 Pfam PF02311 AraC-like ligand binding domain 22 87 4.1E-10 T 13-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 Gene3D G3DSA:1.10.10.60 224 279 8.1E-16 T 13-10-2018 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 Pfam PF12833 Helix-turn-helix domain 196 274 2.7E-20 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2747 b82b91bdefdc7e2572e94c99bc1bf935 280 SMART SM00342 190 273 2.0E-25 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2297 4e4537d11565180908faf93d41d81ce5 468 Gene3D G3DSA:2.115.10.20 2 329 1.0E-64 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2297 4e4537d11565180908faf93d41d81ce5 468 SUPERFAMILY SSF75005 8 327 1.57E-38 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2297 4e4537d11565180908faf93d41d81ce5 468 Pfam PF04616 Glycosyl hydrolases family 43 57 317 3.2E-21 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spica_1937 f856612302307a2ce072552df0dec46a 673 Gene3D G3DSA:3.40.50.300 1 212 2.5E-73 T 13-10-2018 Spica_1937 f856612302307a2ce072552df0dec46a 673 Pfam PF00271 Helicase conserved C-terminal domain 430 542 3.1E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1937 f856612302307a2ce072552df0dec46a 673 SUPERFAMILY SSF52540 3 412 1.59E-130 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1937 f856612302307a2ce072552df0dec46a 673 SMART SM00490 457 543 4.1E-20 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1937 f856612302307a2ce072552df0dec46a 673 Pfam PF12344 Ultra-violet resistance protein B 549 590 4.2E-22 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain Spica_1937 f856612302307a2ce072552df0dec46a 673 Gene3D G3DSA:3.40.50.300 412 593 2.2E-50 T 13-10-2018 Spica_1937 f856612302307a2ce072552df0dec46a 673 Gene3D G3DSA:3.40.50.300 271 411 3.7E-51 T 13-10-2018 Spica_1937 f856612302307a2ce072552df0dec46a 673 Pfam PF02151 UvrB/uvrC motif 626 659 8.6E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 Spica_1937 f856612302307a2ce072552df0dec46a 673 SUPERFAMILY SSF46600 615 661 3.14E-11 T 13-10-2018 IPR036876 UVR domain superfamily Spica_1937 f856612302307a2ce072552df0dec46a 673 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 658 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Spica_1937 f856612302307a2ce072552df0dec46a 673 SMART SM00487 8 423 1.2E-24 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1937 f856612302307a2ce072552df0dec46a 673 SUPERFAMILY SSF52540 35 590 2.48E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1937 f856612302307a2ce072552df0dec46a 673 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 660 42.654 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Spica_1937 f856612302307a2ce072552df0dec46a 673 Gene3D G3DSA:4.10.860.10 614 662 3.6E-11 T 13-10-2018 Spica_1937 f856612302307a2ce072552df0dec46a 673 Pfam PF04851 Type III restriction enzyme, res subunit 15 138 1.3E-10 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spica_0060 1713cc2dd4e499327c69d5795e69efbe 300 SUPERFAMILY SSF161098 59 287 1.44E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0060 1713cc2dd4e499327c69d5795e69efbe 300 Gene3D G3DSA:1.10.3720.10 55 298 2.3E-61 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0060 1713cc2dd4e499327c69d5795e69efbe 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 295 1.8E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0817 20136b2bd78fa8f49594d0febc692098 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 304 1.2E-48 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0488 7a77caa0dd04559307dc57f76d89c45c 77 Hamap MF_00088 UPF0109 protein . 2 76 22.885 T 13-10-2018 IPR020627 Uncharacterised protein family UPF0109 Spica_0488 7a77caa0dd04559307dc57f76d89c45c 77 Pfam PF13083 KH domain 3 75 1.1E-22 T 13-10-2018 Spica_0488 7a77caa0dd04559307dc57f76d89c45c 77 SUPERFAMILY SSF54814 4 62 2.88E-8 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Spica_0488 7a77caa0dd04559307dc57f76d89c45c 77 Gene3D G3DSA:3.30.300.20 5 66 1.4E-5 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Gene3D G3DSA:1.10.10.660 190 256 1.0E-77 T 13-10-2018 IPR024033 Uncharacterised domain superfamily, YlbE Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Gene3D G3DSA:3.40.50.261 1 43 1.7E-7 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Gene3D G3DSA:3.40.50.720 65 154 9.0E-12 T 13-10-2018 Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Gene3D G3DSA:3.90.1700.10 398 552 1.1E-56 T 13-10-2018 Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Gene3D G3DSA:3.90.1710.10 257 389 1.0E-77 T 13-10-2018 Spica_0610 1d0029e4ad673b9f271d400bf4706c7c 554 Pfam PF06545 Protein of unknown function (DUF1116) 236 450 7.9E-94 T 13-10-2018 IPR009499 Protein of unknown function DUF1116 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 Gene3D G3DSA:1.10.132.20 11 181 7.4E-72 T 13-10-2018 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 Pfam PF01765 Ribosome recycling factor 19 182 6.4E-67 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 2 184 28.132 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 SUPERFAMILY SSF55194 4 183 5.36E-72 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 Gene3D G3DSA:3.30.1360.40 30 104 7.4E-72 T 13-10-2018 Spica_1417 69118c68611046f0a4bb0ed94a92aab5 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 9 184 1.2E-71 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Spica_0252 0764d446bbc3282cfd23e800e4f9bec1 523 Gene3D G3DSA:3.30.1330.60 385 521 8.1E-32 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_0252 0764d446bbc3282cfd23e800e4f9bec1 523 SUPERFAMILY SSF103088 401 516 1.57E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_0252 0764d446bbc3282cfd23e800e4f9bec1 523 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 499 519 4.9E-6 T 13-10-2018 Spica_0252 0764d446bbc3282cfd23e800e4f9bec1 523 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 479 498 4.9E-6 T 13-10-2018 Spica_0252 0764d446bbc3282cfd23e800e4f9bec1 523 Pfam PF00691 OmpA family 411 510 2.3E-17 T 13-10-2018 IPR006665 OmpA-like domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SUPERFAMILY SSF55874 351 470 3.41E-20 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Pfam PF13426 PAS domain 21 114 6.5E-4 T 13-10-2018 IPR000014 PAS domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Pfam PF00989 PAS fold 128 180 3.1E-8 T 13-10-2018 IPR013767 PAS fold GO:0006355 Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Pfam PF07568 Histidine kinase 272 345 2.3E-19 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Gene3D G3DSA:3.30.450.20 1 118 1.2E-11 T 13-10-2018 Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SUPERFAMILY SSF55785 112 250 1.26E-20 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 123 258 2.0E-15 T 13-10-2018 IPR000014 PAS domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 122 2.3E-11 T 13-10-2018 IPR000014 PAS domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SUPERFAMILY SSF55785 3 113 1.26E-10 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Gene3D G3DSA:3.30.565.10 330 471 7.3E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SMART SM00091 5 71 0.0039 T 13-10-2018 IPR000014 PAS domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SMART SM00091 127 195 4.4E-9 T 13-10-2018 IPR000014 PAS domain Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 470 2.1E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 Gene3D G3DSA:3.30.450.20 119 250 2.3E-20 T 13-10-2018 Spica_0774 abf77d574d983aa42b582c4a48a4e76a 471 SMART SM00387 367 471 2.2E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2687 388094ef87d8370ffe737fa988538f6d 626 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 520 531 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 SUPERFAMILY SSF52016 432 620 2.04E-59 T 13-10-2018 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 Pfam PF00920 Dehydratase family 34 618 9.7E-217 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 Gene3D G3DSA:3.50.30.80 432 584 2.6E-55 T 13-10-2018 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 621 43.211 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 SUPERFAMILY SSF143975 4 431 2.88E-128 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_2687 388094ef87d8370ffe737fa988538f6d 626 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 620 9.2E-233 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 Gene3D G3DSA:1.10.10.10 9 74 9.6E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 SUPERFAMILY SSF46785 11 73 7.21E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 SUPERFAMILY SSF53067 79 367 1.65E-17 T 13-10-2018 Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 Gene3D G3DSA:3.30.420.40 77 202 2.1E-15 T 13-10-2018 Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 Pfam PF00480 ROK family 136 261 6.4E-6 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 Gene3D G3DSA:3.30.420.40 203 369 2.1E-10 T 13-10-2018 Spica_0976 f99e8de5fdc5deb68a777161607eebd9 391 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 53 4.2E-9 T 13-10-2018 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 SUPERFAMILY SSF54768 14 83 3.77E-22 T 13-10-2018 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 Gene3D G3DSA:3.30.160.20 13 80 1.1E-29 T 13-10-2018 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 Gene3D G3DSA:3.30.230.10 81 173 8.3E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 15 170 1.2E-64 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 19 82 1.4E-27 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 SUPERFAMILY SSF54211 86 166 8.85E-23 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.988 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Spica_0402 d275784b3e83f5589918ee3ac49e9d84 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 95 164 6.8E-25 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Spica_2210 8548e0696a123e5c6d90ac1fadbb2051 196 Pfam PF13835 Domain of unknown function (DUF4194) 27 177 5.5E-27 T 13-10-2018 IPR025449 Protein of unknown function DUF4194 Spica_2769 0abda0513fa43b26dde1759857357508 178 SUPERFAMILY SSF48452 3 172 1.67E-38 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 Gene3D G3DSA:1.25.40.10 1 175 9.6E-43 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 Pfam PF14559 Tetratricopeptide repeat 15 59 2.2E-7 T 13-10-2018 Spica_2769 0abda0513fa43b26dde1759857357508 178 SMART SM00028 106 139 1.6E-7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 SMART SM00028 72 105 3.8E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 SMART SM00028 38 71 0.0054 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 SMART SM00028 4 37 1.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 Pfam PF00515 Tetratricopeptide repeat 72 102 3.5E-7 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spica_2769 0abda0513fa43b26dde1759857357508 178 Pfam PF00515 Tetratricopeptide repeat 106 139 2.8E-10 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spica_0780 b91d5392a4884333d4324e8c71b62b38 264 SUPERFAMILY SSF64438 48 263 9.16E-43 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spica_0780 b91d5392a4884333d4324e8c71b62b38 264 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 53 263 8.6E-41 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Spica_0780 b91d5392a4884333d4324e8c71b62b38 264 Gene3D G3DSA:3.60.140.10 41 264 3.8E-46 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily Spica_0489 599aee66715b859c92fdc634812d8c7b 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 4 79 8.2E-33 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0489 599aee66715b859c92fdc634812d8c7b 82 Gene3D G3DSA:3.30.1320.10 1 81 1.2E-30 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0489 599aee66715b859c92fdc634812d8c7b 82 SUPERFAMILY SSF54565 3 80 5.36E-30 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0489 599aee66715b859c92fdc634812d8c7b 82 Pfam PF00886 Ribosomal protein S16 9 68 5.6E-24 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0489 599aee66715b859c92fdc634812d8c7b 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 78 24.635 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SUPERFAMILY SSF54814 278 343 6.15E-15 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Gene3D G3DSA:3.30.1480.10 1 123 1.5E-36 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 9.5E-130 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SMART SM00316 133 199 2.5E-9 T 13-10-2018 IPR022967 RNA-binding domain, S1 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SUPERFAMILY SSF69705 1 125 7.72E-34 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SUPERFAMILY SSF54814 199 276 1.05E-29 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Pfam PF08529 NusA N-terminal domain 5 124 2.6E-31 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SUPERFAMILY SSF50249 131 198 3.35E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Gene3D G3DSA:3.30.300.20 278 457 1.1E-38 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Gene3D G3DSA:3.30.300.20 198 276 5.7E-33 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Gene3D G3DSA:2.40.50.140 135 197 3.7E-19 T 13-10-2018 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 447 27.857 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Pfam PF13248 zinc-ribbon domain 457 482 3.9E-7 T 13-10-2018 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Pfam PF00575 S1 RNA binding domain 131 188 1.0E-4 T 13-10-2018 IPR003029 S1 domain GO:0003676 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 Pfam PF13184 NusA-like KH domain 229 297 2.2E-29 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 Spica_1353 97b8ff93931c73a1f59eb0151347c415 490 SUPERFAMILY SSF47794 374 428 4.71E-6 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SUPERFAMILY SSF55785 370 477 2.42E-13 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Gene3D G3DSA:3.30.450.20 370 488 8.5E-15 T 13-10-2018 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SMART SM00388 493 559 0.0032 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Gene3D G3DSA:3.30.565.10 562 734 1.1E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 599 723 3.6E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SUPERFAMILY SSF55785 236 340 4.89E-6 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 364 485 1.6E-9 T 13-10-2018 IPR000014 PAS domain Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Gene3D G3DSA:3.40.50.2300 739 867 6.8E-25 T 13-10-2018 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SMART SM00387 598 725 2.1E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Gene3D G3DSA:3.30.450.20 236 354 3.6E-5 T 13-10-2018 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 684 4.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 PRINTS PR00344 Bacterial sensor protein C-terminal signature 685 703 4.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 722 4.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 670 4.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Gene3D G3DSA:1.10.287.130 489 556 1.6E-16 T 13-10-2018 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SUPERFAMILY SSF47384 486 556 2.16E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Pfam PF13426 PAS domain 250 341 0.37 T 13-10-2018 IPR000014 PAS domain Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Pfam PF13426 PAS domain 375 477 1.7E-10 T 13-10-2018 IPR000014 PAS domain Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SMART SM00091 365 432 0.0011 T 13-10-2018 IPR000014 PAS domain Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SMART SM00091 238 299 89.0 T 13-10-2018 IPR000014 PAS domain Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SMART SM00448 741 858 2.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Pfam PF16927 N-terminal 7TM region of histidine kinase 10 234 5.1E-11 T 13-10-2018 IPR031621 Histidine kinase, N-terminal 7TM region Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SUPERFAMILY SSF52172 740 863 1.11E-24 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 Pfam PF00072 Response regulator receiver domain 743 858 3.2E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2403 5a46585c025bed43883b7f2eb62ca882 869 SUPERFAMILY SSF55874 549 723 6.02E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:1.10.287.470 239 266 1.1E-33 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:1.10.287.470 102 148 2.1E-6 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 239 457 9.1E-40 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 225 376 1.3E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:2.40.50.100 267 305 1.1E-33 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:2.40.50.100 68 101 2.1E-6 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 SUPERFAMILY SSF111369 231 383 2.75E-12 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:2.40.30.170 306 383 1.1E-33 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:2.40.30.170 58 67 2.1E-6 T 13-10-2018 Spica_1062 c6d136a6b22b9cbda0256814367e235f 459 Gene3D G3DSA:2.40.420.20 384 453 1.1E-33 T 13-10-2018 Spica_2707 fedaf0ee3a2c98634d3612b6cc46032c 217 Pfam PF10688 Bacterial inner membrane protein 3 71 5.0E-6 T 13-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV Spica_2707 fedaf0ee3a2c98634d3612b6cc46032c 217 ProDom PD058023 TRANSMEMBRANE SO1069 MEMBRANE VCA0743 SO4196 VVA0623 VPA0666 HI1736 PM0424 6 66 2.0E-12 T 13-10-2018 IPR020137 Uncharacterised protein family HI1736 Spica_0629 62c240e295f010007c629f374cdd458d 253 Pfam PF09339 IclR helix-turn-helix domain 9 58 7.4E-12 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spica_0629 62c240e295f010007c629f374cdd458d 253 Gene3D G3DSA:1.10.10.10 5 76 3.1E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0629 62c240e295f010007c629f374cdd458d 253 SMART SM00346 7 95 7.1E-21 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Spica_0629 62c240e295f010007c629f374cdd458d 253 Gene3D G3DSA:3.30.450.40 77 253 1.3E-62 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0629 62c240e295f010007c629f374cdd458d 253 SUPERFAMILY SSF46785 7 78 5.55E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0629 62c240e295f010007c629f374cdd458d 253 SUPERFAMILY SSF55781 70 251 1.5E-52 T 13-10-2018 Spica_0629 62c240e295f010007c629f374cdd458d 253 Pfam PF01614 Bacterial transcriptional regulator 122 247 8.7E-43 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 1.6E-94 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 SUPERFAMILY SSF52540 184 433 7.75E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 SMART SM00382 202 396 0.0039 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 SUPERFAMILY SSF48024 8 118 3.01E-34 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 4.3E-32 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 Gene3D G3DSA:1.10.860.10 1 166 1.4E-52 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 442 3.9E-150 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 Spica_1424 ee0149a51a8cd91d2678c20f4fc31e2e 446 Gene3D G3DSA:3.40.50.300 168 445 5.8E-97 T 13-10-2018 Spica_0528 304ffad424a563b40deb62a10a8850d2 287 Pfam PF00483 Nucleotidyl transferase 2 238 4.4E-68 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_0528 304ffad424a563b40deb62a10a8850d2 287 SUPERFAMILY SSF53448 1 273 9.32E-89 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0528 304ffad424a563b40deb62a10a8850d2 287 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 284 1.7E-144 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Spica_0528 304ffad424a563b40deb62a10a8850d2 287 Gene3D G3DSA:3.90.550.10 1 287 2.6E-81 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1159 b04b55f03442037f12775be8b4f4c85a 236 Gene3D G3DSA:3.60.15.10 53 232 2.6E-39 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1159 b04b55f03442037f12775be8b4f4c85a 236 SUPERFAMILY SSF56281 57 218 5.18E-40 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1159 b04b55f03442037f12775be8b4f4c85a 236 SMART SM00849 50 202 7.7E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1159 b04b55f03442037f12775be8b4f4c85a 236 Pfam PF00753 Metallo-beta-lactamase superfamily 58 202 3.4E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0179 1b629f4283a6ea25974bba803238d698 649 SMART SM00729 311 564 2.6E-10 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_0179 1b629f4283a6ea25974bba803238d698 649 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 12 578 3.3E-247 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 Spica_0179 1b629f4283a6ea25974bba803238d698 649 SUPERFAMILY SSF102114 315 555 3.92E-14 T 13-10-2018 Spica_0179 1b629f4283a6ea25974bba803238d698 649 Pfam PF11842 Domain of unknown function (DUF3362) 532 633 4.0E-36 T 13-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal Spica_0179 1b629f4283a6ea25974bba803238d698 649 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 12 579 52.685 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 Spica_0179 1b629f4283a6ea25974bba803238d698 649 Pfam PF08497 Radical SAM N-terminal 12 314 4.9E-128 T 13-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal Spica_0179 1b629f4283a6ea25974bba803238d698 649 Pfam PF04055 Radical SAM superfamily 316 523 1.6E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_0179 1b629f4283a6ea25974bba803238d698 649 Gene3D G3DSA:3.80.30.20 312 559 3.4E-12 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1436 e3baa576dd5ff1ede87b79bca2123e0a 453 Pfam PF04286 Protein of unknown function (DUF445) 13 447 1.3E-41 T 13-10-2018 IPR007383 Protein of unknown function DUF445 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 91 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 PIRSF PIRSF006769 1 366 3.8E-128 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 Pfam PF01872 RibD C-terminal domain 150 359 3.3E-53 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 Gene3D G3DSA:3.40.140.10 1 144 2.9E-48 T 13-10-2018 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 361 4.9E-66 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 103 1.9E-20 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 SUPERFAMILY SSF53927 1 147 3.35E-47 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 Gene3D G3DSA:3.40.430.10 145 363 3.5E-71 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 SUPERFAMILY SSF53597 150 360 6.25E-57 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Spica_0166 e5cfdb5408e17ae0587648ba0ebc1e57 368 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 359 4.2E-107 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 Spica_1140 92f07042c233e648fbdc114b3c00ad91 329 Pfam PF02272 DHHA1 domain 213 308 4.8E-10 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Spica_1140 92f07042c233e648fbdc114b3c00ad91 329 Gene3D G3DSA:3.90.1640.10 2 204 3.3E-43 T 13-10-2018 Spica_1140 92f07042c233e648fbdc114b3c00ad91 329 Gene3D G3DSA:3.10.310.30 207 326 2.8E-33 T 13-10-2018 Spica_1140 92f07042c233e648fbdc114b3c00ad91 329 Pfam PF01368 DHH family 19 163 9.9E-12 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_1140 92f07042c233e648fbdc114b3c00ad91 329 SUPERFAMILY SSF64182 16 308 8.11E-54 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_0366 8a21d7cfa33e94d3535a56783ef84e1e 508 Gene3D G3DSA:2.40.50.140 441 508 2.0E-8 T 13-10-2018 Spica_0366 8a21d7cfa33e94d3535a56783ef84e1e 508 SUPERFAMILY SSF52096 15 240 1.49E-14 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_0366 8a21d7cfa33e94d3535a56783ef84e1e 508 Pfam PF01957 NfeD-like C-terminal, partner-binding 326 506 3.0E-7 T 13-10-2018 IPR002810 NfeD-like, C-terminal domain Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 19 333 9.5E-128 T 13-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 SUPERFAMILY SSF55681 15 337 2.93E-95 T 13-10-2018 Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 PIRSF PIRSF001555 7 344 3.7E-153 T 13-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 Gene3D G3DSA:3.30.930.10 13 339 7.8E-146 T 13-10-2018 Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 Pfam PF03590 Aspartate-ammonia ligase 19 254 1.3E-102 T 13-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 Spica_0929 dc8cd3a53ebb1b15df7d7fc10b4091c5 344 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 11 340 48.596 T 13-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.8E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 Gene3D G3DSA:1.10.260.40 1 60 1.2E-18 T 13-10-2018 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 Gene3D G3DSA:3.40.50.2300 75 312 2.7E-64 T 13-10-2018 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 SUPERFAMILY SSF53822 74 336 4.89E-64 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 SUPERFAMILY SSF47413 1 59 1.34E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 Gene3D G3DSA:3.40.50.2300 163 295 2.7E-64 T 13-10-2018 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 SMART SM00354 1 71 3.4E-20 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_1965 42aa99bb34a52ec5a47f38f1394d2e2e 338 Pfam PF13377 Periplasmic binding protein-like domain 171 334 2.8E-40 T 13-10-2018 Spica_2061 0cb09b3679562fe9a205dcd7795b444c 259 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 180 244 2.7E-9 T 13-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 Spica_2061 0cb09b3679562fe9a205dcd7795b444c 259 SUPERFAMILY SSF81296 180 252 2.27E-14 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_2061 0cb09b3679562fe9a205dcd7795b444c 259 Gene3D G3DSA:2.60.40.10 164 258 2.0E-18 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Gene3D G3DSA:1.10.287.560 343 410 1.3E-6 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SMART SM01231 342 467 2.7E-14 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SUPERFAMILY SSF55874 469 651 2.62E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Pfam PF01584 CheW-like domain 657 784 6.6E-29 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SMART SM00260 645 783 1.3E-43 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Gene3D G3DSA:1.20.120.160 7 147 6.4E-33 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Pfam PF01627 Hpt domain 11 100 4.6E-16 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Gene3D G3DSA:3.30.565.10 466 652 2.1E-62 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SUPERFAMILY SSF47384 344 377 1.77E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 607 6.7E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 571 6.7E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 637 650 6.7E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 631 6.7E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SMART SM00387 512 653 5.6E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SUPERFAMILY SSF50341 652 783 1.57E-34 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SMART SM00073 9 106 8.1E-29 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Gene3D G3DSA:2.30.30.40 653 779 1.8E-40 T 13-10-2018 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 516 652 2.6E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 343 467 1.6E-23 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Gene3D G3DSA:2.40.50.180 676 738 1.8E-40 T 13-10-2018 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SUPERFAMILY SSF55052 188 258 6.54E-12 T 13-10-2018 IPR035891 CheY-binding domain of CheA Spica_0958 2179bcf86c9c01484867439e88586fc6 802 Pfam PF07194 P2 response regulator binding domain 191 268 4.8E-12 T 13-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 Spica_0958 2179bcf86c9c01484867439e88586fc6 802 SUPERFAMILY SSF47226 10 119 1.44E-27 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Spica_0641 600311795a62a2a871214fad832db8e1 285 SUPERFAMILY SSF51658 15 269 4.15E-32 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Spica_0641 600311795a62a2a871214fad832db8e1 285 Pfam PF01261 Xylose isomerase-like TIM barrel 22 240 1.8E-25 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Spica_0641 600311795a62a2a871214fad832db8e1 285 Gene3D G3DSA:3.20.20.150 2 283 6.1E-39 T 13-10-2018 Spica_0644 706becb5204f953efac8521dca65c068 359 Gene3D G3DSA:1.20.1530.20 2 339 2.0E-28 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Spica_0644 706becb5204f953efac8521dca65c068 359 Pfam PF01758 Sodium Bile acid symporter family 51 248 1.8E-50 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spica_0644 706becb5204f953efac8521dca65c068 359 PIRSF PIRSF005508 1 354 6.5E-130 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spica_0644 706becb5204f953efac8521dca65c068 359 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 6 336 3.2E-118 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 159 174 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 PIRSF PIRSF001563 3 462 1.1E-98 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 Gene3D G3DSA:3.40.1190.10 1 322 2.3E-80 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 457 3.8E-97 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 Gene3D G3DSA:3.90.190.20 325 461 1.7E-25 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 SUPERFAMILY SSF53623 22 321 2.06E-71 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 SUPERFAMILY SSF53244 323 458 2.2E-22 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 Pfam PF08245 Mur ligase middle domain 53 301 3.5E-10 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Spica_1580 eb05ae20ea55b386ba036af04e345618 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 384 2.6E-6 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Spica_0289 1841393bb7ac5ead665417b26a5b9780 259 Gene3D G3DSA:2.50.20.10 25 257 1.1E-74 T 13-10-2018 Spica_0289 1841393bb7ac5ead665417b26a5b9780 259 Pfam PF17131 Outer membrane lipoprotein-sorting protein 76 256 3.8E-67 T 13-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein Spica_2245 72c564da60da438d305eefb4280acf90 145 Gene3D G3DSA:3.40.1650.10 1 143 2.3E-46 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_2245 72c564da60da438d305eefb4280acf90 145 SUPERFAMILY SSF102546 1 141 3.27E-40 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_2245 72c564da60da438d305eefb4280acf90 145 Pfam PF05025 RbsD / FucU transport protein family 4 141 6.1E-34 T 13-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 SMART SM00028 178 211 1.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 SMART SM00028 109 142 1.8E-6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 SMART SM00028 38 71 28.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 SMART SM00028 143 177 51.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 Gene3D G3DSA:1.25.40.10 6 109 6.1E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 Gene3D G3DSA:1.25.40.10 110 222 7.1E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 Pfam PF13432 Tetratricopeptide repeat 115 178 1.4E-9 T 13-10-2018 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 Pfam PF13432 Tetratricopeptide repeat 8 65 3.8E-4 T 13-10-2018 Spica_1314 b024d1b81be1278a495b8185e40e8efb 225 SUPERFAMILY SSF48452 6 214 1.86E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0529 5727f1233412599bdbf88b922ea37414 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 10 176 2.0E-62 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_0529 5727f1233412599bdbf88b922ea37414 182 SUPERFAMILY SSF51182 4 178 1.54E-76 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0529 5727f1233412599bdbf88b922ea37414 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 176 2.3E-75 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_0529 5727f1233412599bdbf88b922ea37414 182 Gene3D G3DSA:2.60.120.10 3 182 9.3E-75 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0529 5727f1233412599bdbf88b922ea37414 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 177 3.1E-76 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_1351 b7c7aad46727db23eae337f5214518fc 269 SUPERFAMILY SSF53271 69 267 1.5E-16 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_1351 b7c7aad46727db23eae337f5214518fc 269 Gene3D G3DSA:3.40.50.2020 110 268 9.8E-13 T 13-10-2018 Spica_1351 b7c7aad46727db23eae337f5214518fc 269 Pfam PF00156 Phosphoribosyl transferase domain 226 268 7.1E-8 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 11 624 6.2E-211 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Gene3D G3DSA:3.40.50.920 494 626 2.0E-20 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Pfam PF02779 Transketolase, pyrimidine binding domain 319 480 4.9E-36 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 SUPERFAMILY SSF52518 4 381 6.55E-74 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 SMART SM00861 319 482 2.5E-58 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 SUPERFAMILY SSF52922 499 625 1.7E-16 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 ProSitePatterns PS00801 Transketolase signature 1. 34 53 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 8 625 41.526 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Gene3D G3DSA:3.40.50.970 317 487 2.5E-62 T 13-10-2018 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Pfam PF02780 Transketolase, C-terminal domain 503 611 1.5E-13 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Spica_1199 57f6217a8eaa5c0638e035a2987e29f2 642 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 9 284 1.0E-116 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Spica_1363 e108ac209a415ff170934f113e5103fd 452 Gene3D G3DSA:1.25.10.110 84 160 4.2E-5 T 13-10-2018 Spica_1363 e108ac209a415ff170934f113e5103fd 452 SMART SM00567 E-Z type HEAT repeats 108 136 530.0 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_1363 e108ac209a415ff170934f113e5103fd 452 SMART SM00567 E-Z type HEAT repeats 242 271 22.0 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_1363 e108ac209a415ff170934f113e5103fd 452 SMART SM00567 E-Z type HEAT repeats 305 334 16.0 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_1363 e108ac209a415ff170934f113e5103fd 452 SMART SM00567 E-Z type HEAT repeats 211 240 31.0 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_1363 e108ac209a415ff170934f113e5103fd 452 SUPERFAMILY SSF48371 112 342 9.6E-29 T 13-10-2018 IPR016024 Armadillo-type fold Spica_1363 e108ac209a415ff170934f113e5103fd 452 Pfam PF13646 HEAT repeats 231 316 8.8E-15 T 13-10-2018 Spica_1363 e108ac209a415ff170934f113e5103fd 452 Gene3D G3DSA:1.25.10.10 161 337 2.8E-27 T 13-10-2018 IPR011989 Armadillo-like helical Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 Pfam PF00005 ABC transporter 430 577 3.7E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 SUPERFAMILY SSF90123 25 380 7.06E-62 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 SMART SM00382 439 626 1.6E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 Gene3D G3DSA:3.40.50.300 406 655 5.6E-83 T 13-10-2018 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 ProSitePatterns PS00211 ABC transporters family signature. 551 565 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 Pfam PF00664 ABC transporter transmembrane region 121 355 2.8E-43 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 Gene3D G3DSA:1.20.1560.10 93 380 1.4E-66 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2424 31c4628bcb5551b8eff9c374bef17826 656 SUPERFAMILY SSF52540 408 650 1.13E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2208 9e83ac12fb6886eeb8be1e9400e046e6 381 SUPERFAMILY SSF53474 99 254 4.75E-11 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2208 9e83ac12fb6886eeb8be1e9400e046e6 381 Pfam PF11187 Protein of unknown function (DUF2974) 92 314 6.5E-82 T 13-10-2018 IPR024499 Protein of unknown function DUF2974 Spica_2096 0cef5e4111beb3dc4e53b1219f522b01 285 Gene3D G3DSA:3.90.550.10 1 280 8.1E-67 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2096 0cef5e4111beb3dc4e53b1219f522b01 285 Pfam PF00483 Nucleotidyl transferase 2 261 2.2E-30 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_2096 0cef5e4111beb3dc4e53b1219f522b01 285 SUPERFAMILY SSF53448 1 267 8.11E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 Gene3D G3DSA:3.20.20.80 151 599 1.0E-191 T 13-10-2018 Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 SMART SM00642 148 576 2.6E-8 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 107 7.7E-16 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 SUPERFAMILY SSF51445 148 592 2.07E-129 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 Gene3D G3DSA:2.60.40.10 1 150 4.7E-42 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 SUPERFAMILY SSF51011 607 715 1.15E-18 T 13-10-2018 Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 Pfam PF00128 Alpha amylase, catalytic domain 191 295 2.2E-10 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 SUPERFAMILY SSF81296 11 161 1.82E-40 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 Gene3D G3DSA:2.60.40.1180 604 715 9.8E-25 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2840 e03e42847c48c5c36f77de6b69d6ecff 717 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 11 711 1.0E-245 T 13-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 Gene3D G3DSA:3.30.420.40 1 88 1.5E-28 T 13-10-2018 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 SUPERFAMILY SSF53067 124 251 1.33E-34 T 13-10-2018 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 250 1.4E-68 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 SUPERFAMILY SSF53067 1 120 1.07E-27 T 13-10-2018 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 253 28.536 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 Pfam PF03309 Type III pantothenate kinase 2 205 1.8E-57 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_1335 45c572a4d14e976c8a13559c6f6d0800 253 Gene3D G3DSA:3.30.420.40 89 253 9.2E-50 T 13-10-2018 Spica_1582 e813151e33d068038d48663733bb7506 253 Gene3D G3DSA:3.30.2350.10 3 252 8.7E-38 T 13-10-2018 Spica_1582 e813151e33d068038d48663733bb7506 253 Pfam PF00849 RNA pseudouridylate synthase 17 205 1.3E-17 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1582 e813151e33d068038d48663733bb7506 253 SUPERFAMILY SSF55120 7 249 3.2E-33 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 42 176 3.2E-16 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 SUPERFAMILY SSF51306 58 327 1.86E-42 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 Gene3D G3DSA:2.10.109.10 235 327 1.1E-13 T 13-10-2018 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 Pfam PF00717 Peptidase S24-like 65 116 9.7E-7 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 281 300 2.3E-19 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 59 75 2.3E-19 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 155 167 2.3E-19 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1300 df3d28fca146c9fe5679faebbcdabb40 328 Pfam PF10502 Signal peptidase, peptidase S26 264 313 3.0E-5 T 13-10-2018 IPR019533 Peptidase S26 Spica_1399 93f5dd25472843b9de86661be79ca6ea 129 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 18 121 2.0E-24 T 13-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Spica_1399 93f5dd25472843b9de86661be79ca6ea 129 Gene3D G3DSA:3.30.1330.40 5 127 3.2E-39 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Spica_1399 93f5dd25472843b9de86661be79ca6ea 129 Pfam PF07736 Chorismate mutase type I 8 121 5.7E-37 T 13-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Spica_1399 93f5dd25472843b9de86661be79ca6ea 129 SUPERFAMILY SSF55298 6 123 4.0E-33 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Spica_1399 93f5dd25472843b9de86661be79ca6ea 129 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 8 121 1.3E-27 T 13-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Spica_0835 c2d5a7919dc4d11d3a8756c24ceef025 386 Gene3D G3DSA:3.40.50.2300 152 284 6.7E-97 T 13-10-2018 Spica_0835 c2d5a7919dc4d11d3a8756c24ceef025 386 Gene3D G3DSA:3.40.50.2300 67 366 6.7E-97 T 13-10-2018 Spica_0835 c2d5a7919dc4d11d3a8756c24ceef025 386 Pfam PF13458 Periplasmic binding protein 33 376 4.0E-50 T 13-10-2018 IPR028081 Leucine-binding protein domain Spica_0835 c2d5a7919dc4d11d3a8756c24ceef025 386 SUPERFAMILY SSF53822 31 380 3.93E-75 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2089 2ffcb3f4b388b5316359e999ea9432ac 162 PIRSF PIRSF005384 5 151 3.5E-36 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Spica_2089 2ffcb3f4b388b5316359e999ea9432ac 162 Gene3D G3DSA:3.40.1400.10 1 151 5.1E-39 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Spica_2089 2ffcb3f4b388b5316359e999ea9432ac 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 8 138 2.4E-31 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Spica_2089 2ffcb3f4b388b5316359e999ea9432ac 162 Pfam PF02502 Ribose/Galactose Isomerase 8 138 5.9E-35 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Spica_2089 2ffcb3f4b388b5316359e999ea9432ac 162 SUPERFAMILY SSF89623 5 140 1.15E-37 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 Pfam PF00158 Sigma-54 interaction domain 136 300 1.4E-55 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 SUPERFAMILY SSF52540 136 369 5.25E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 159 172 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 Pfam PF00072 Response regulator receiver domain 4 111 8.6E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 Gene3D G3DSA:3.40.50.2300 2 126 1.1E-23 T 13-10-2018 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 SMART SM00382 155 299 3.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 220 235 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 Gene3D G3DSA:1.10.8.60 305 366 2.1E-15 T 13-10-2018 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 SMART SM00448 2 112 1.9E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 SUPERFAMILY SSF52172 1 179 8.25E-30 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0236 9ca49fb09e34aeb3355da777e12506ec 371 Gene3D G3DSA:3.40.50.300 127 304 4.2E-57 T 13-10-2018 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 Pfam PF02110 Hydroxyethylthiazole kinase family 15 259 1.4E-79 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PIRSF PIRSF000513 10 272 9.3E-86 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 15 260 7.0E-82 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 23 30 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 166 183 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 124 138 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 67 75 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 93 110 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 36 57 9.9E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0171 0599f8a81baf9f66559900e7f246da21 274 Gene3D G3DSA:3.40.1190.20 1 272 4.6E-95 T 13-10-2018 IPR029056 Ribokinase-like Spica_0171 0599f8a81baf9f66559900e7f246da21 274 SUPERFAMILY SSF53613 14 263 7.95E-53 T 13-10-2018 IPR029056 Ribokinase-like Spica_0171 0599f8a81baf9f66559900e7f246da21 274 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 17 264 31.433 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 Gene3D G3DSA:3.40.50.12740 3 265 5.2E-31 T 13-10-2018 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 480 522 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 Pfam PF00072 Response regulator receiver domain 5 116 4.7E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 SUPERFAMILY SSF46689 479 529 1.52E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 Gene3D G3DSA:1.10.10.60 424 480 1.1E-17 T 13-10-2018 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 Gene3D G3DSA:1.10.10.2730 481 526 1.9E-14 T 13-10-2018 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 SMART SM00448 2 116 1.1E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 SMART SM00342 443 526 4.2E-27 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 Pfam PF12833 Helix-turn-helix domain 449 526 4.9E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 SUPERFAMILY SSF46689 426 477 3.94E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2322 c0eae31fb9865318c880eda2465e4a6b 541 SUPERFAMILY SSF52172 2 130 2.7E-32 T 13-10-2018 IPR011006 CheY-like superfamily Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Pfam PF03065 Glycosyl hydrolase family 57 27 175 7.5E-23 T 13-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Gene3D G3DSA:2.70.98.10 356 410 6.5E-8 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Gene3D G3DSA:3.20.110.20 1 344 1.2E-80 T 13-10-2018 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Pfam PF09094 Domain of unknown function (DUF1925) 273 346 5.2E-10 T 13-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Pfam PF09095 Domain of unknown function (DUF1926) 415 606 1.5E-7 T 13-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 Pfam PF09095 Domain of unknown function (DUF1926) 361 409 3.1E-6 T 13-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 SUPERFAMILY SSF88713 4 178 1.67E-37 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 SUPERFAMILY SSF74650 355 516 4.39E-15 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_1282 aee7074ea6f11cb8ece8dc92be439e12 613 SUPERFAMILY SSF88688 273 345 1.18E-5 T 13-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily Spica_2763 ca1896364212151e99e7e5d194e43428 544 Hamap MF_01227 CTP synthase [pyrG]. 2 539 46.93 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Spica_2763 ca1896364212151e99e7e5d194e43428 544 TIGRFAM TIGR00337 PyrG: CTP synthase 2 534 4.6E-223 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Spica_2763 ca1896364212151e99e7e5d194e43428 544 SUPERFAMILY SSF52317 290 540 3.21E-74 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2763 ca1896364212151e99e7e5d194e43428 544 Pfam PF00117 Glutamine amidotransferase class-I 302 533 6.5E-48 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_2763 ca1896364212151e99e7e5d194e43428 544 Gene3D G3DSA:3.40.50.880 288 544 5.4E-93 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_2763 ca1896364212151e99e7e5d194e43428 544 SUPERFAMILY SSF52540 1 269 2.39E-111 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2763 ca1896364212151e99e7e5d194e43428 544 Pfam PF06418 CTP synthase N-terminus 3 266 1.0E-117 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Spica_2763 ca1896364212151e99e7e5d194e43428 544 Gene3D G3DSA:3.40.50.300 1 286 1.8E-124 T 13-10-2018 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 SUPERFAMILY SSF46894 143 211 1.36E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 Gene3D G3DSA:3.40.50.12740 5 211 3.8E-72 T 13-10-2018 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 SMART SM00448 5 118 1.9E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 SMART SM00421 148 205 2.3E-23 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 SUPERFAMILY SSF52172 4 136 7.4E-37 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.0E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 Pfam PF00072 Response regulator receiver domain 7 119 9.3E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_2130 bbbfddad6d300a8f03a4a9422db6c561 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_1926 a98db3a000d1123eb09ac1325b99e4ac 289 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 5 275 2.5E-83 T 13-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Spica_1926 a98db3a000d1123eb09ac1325b99e4ac 289 Pfam PF05107 CRISPR-associated protein Cas7 6 275 2.2E-111 T 13-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C Spica_1926 a98db3a000d1123eb09ac1325b99e4ac 289 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 7 287 1.1E-111 T 13-10-2018 IPR013418 CRISPR-associated protein Csd2 Spica_2032 0a2b08818b247781be21cac7d64e5750 469 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 282 467 8.8E-25 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2032 0a2b08818b247781be21cac7d64e5750 469 SUPERFAMILY SSF161098 259 460 1.7E-21 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2032 0a2b08818b247781be21cac7d64e5750 469 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 8 57 5.1E-5 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spica_2032 0a2b08818b247781be21cac7d64e5750 469 Gene3D G3DSA:1.10.3720.10 254 467 2.9E-16 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2148 4cd3351f8e03130f1aa983165a8e65a3 328 SUPERFAMILY SSF53822 41 314 1.18E-64 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2148 4cd3351f8e03130f1aa983165a8e65a3 328 Gene3D G3DSA:3.40.50.2300 143 313 1.4E-75 T 13-10-2018 Spica_2148 4cd3351f8e03130f1aa983165a8e65a3 328 Gene3D G3DSA:3.40.50.2300 48 305 1.4E-75 T 13-10-2018 Spica_2148 4cd3351f8e03130f1aa983165a8e65a3 328 Pfam PF13407 Periplasmic binding protein domain 42 296 3.2E-50 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 SUPERFAMILY SSF52172 1 190 3.27E-37 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 SUPERFAMILY SSF52540 146 388 9.13E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Pfam PF00158 Sigma-54 interaction domain 146 312 5.9E-67 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Gene3D G3DSA:3.40.50.2300 1 129 8.0E-29 T 13-10-2018 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 SMART SM00382 166 309 1.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Gene3D G3DSA:3.40.50.300 135 316 7.7E-63 T 13-10-2018 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Pfam PF02954 Bacterial regulatory protein, Fis family 408 448 4.0E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 451 2.8E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 431 2.8E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Gene3D G3DSA:1.10.8.60 317 391 2.5E-29 T 13-10-2018 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 SUPERFAMILY SSF46689 360 448 1.12E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Gene3D G3DSA:1.10.10.60 392 450 5.7E-11 T 13-10-2018 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 SMART SM00448 2 116 1.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_2485 4a9f9e2ccba8502f3f7d1f87c978122f 457 Pfam PF00072 Response regulator receiver domain 4 115 1.3E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2360 df7acc1c1d1ff9913c5dc0624499c82a 483 SUPERFAMILY SSF53383 35 481 1.13E-100 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2360 df7acc1c1d1ff9913c5dc0624499c82a 483 Gene3D G3DSA:3.90.1150.10 337 468 3.4E-42 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2360 df7acc1c1d1ff9913c5dc0624499c82a 483 Pfam PF02347 Glycine cleavage system P-protein 97 301 5.5E-6 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Spica_2360 df7acc1c1d1ff9913c5dc0624499c82a 483 Gene3D G3DSA:3.40.640.10 82 323 2.4E-54 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 SMART SM00228 302 384 1.1E-12 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 SMART SM00228 409 489 3.7E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 137 149 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 199 223 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 234 251 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 158 178 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 256 273 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 PRINTS PR00834 HtrA/DegQ protease family signature 342 354 1.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 67 493 6.2E-144 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Pfam PF13180 PDZ domain 430 491 1.3E-7 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Pfam PF13180 PDZ domain 302 392 9.5E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 SUPERFAMILY SSF50494 68 299 1.23E-58 T 13-10-2018 IPR009003 Peptidase S1, PA clan Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Gene3D G3DSA:2.30.42.10 404 498 4.9E-17 T 13-10-2018 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Gene3D G3DSA:2.30.42.10 297 403 6.3E-24 T 13-10-2018 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 SUPERFAMILY SSF50156 408 493 1.84E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 SUPERFAMILY SSF50156 260 384 2.1E-21 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Pfam PF13365 Trypsin-like peptidase domain 125 263 1.4E-31 T 13-10-2018 Spica_1809 dbc13375613942f0a9fc54ebc7bb9bf9 500 Gene3D G3DSA:2.40.10.120 66 295 2.7E-74 T 13-10-2018 Spica_2343 9e4cabba6e5b5e59db06ba042be529f3 123 SMART SM00448 3 117 7.2E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2343 9e4cabba6e5b5e59db06ba042be529f3 123 SUPERFAMILY SSF52172 3 122 1.1E-30 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2343 9e4cabba6e5b5e59db06ba042be529f3 123 Gene3D G3DSA:3.40.50.2300 2 123 2.5E-29 T 13-10-2018 Spica_2343 9e4cabba6e5b5e59db06ba042be529f3 123 Pfam PF00072 Response regulator receiver domain 5 117 1.3E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0057 20ea40d36d74e1d537ad727e49b44eb4 230 SUPERFAMILY SSF109854 48 123 5.31E-7 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Spica_0057 20ea40d36d74e1d537ad727e49b44eb4 230 Pfam PF12867 DinB superfamily 47 210 1.0E-6 T 13-10-2018 IPR024775 DinB-like domain Spica_0057 20ea40d36d74e1d537ad727e49b44eb4 230 Gene3D G3DSA:1.20.120.450 35 212 4.8E-23 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Spica_2686 3d4c478a441c132cb964c54ffbf4adbe 258 Pfam PF01872 RibD C-terminal domain 20 251 3.0E-42 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Spica_2686 3d4c478a441c132cb964c54ffbf4adbe 258 SUPERFAMILY SSF53597 18 253 1.47E-49 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Spica_2686 3d4c478a441c132cb964c54ffbf4adbe 258 Gene3D G3DSA:3.40.430.10 15 256 7.8E-64 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Spica_2686 3d4c478a441c132cb964c54ffbf4adbe 258 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 19 252 2.6E-45 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Spica_0073 e6d1d4762cb76e87a6efcc7cfbd1b266 388 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 13-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 Spica_0073 e6d1d4762cb76e87a6efcc7cfbd1b266 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 15 380 8.4E-112 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Spica_0073 e6d1d4762cb76e87a6efcc7cfbd1b266 388 Gene3D G3DSA:3.40.50.1970 5 187 2.0E-55 T 13-10-2018 Spica_0073 e6d1d4762cb76e87a6efcc7cfbd1b266 388 SUPERFAMILY SSF56796 11 386 1.96E-118 T 13-10-2018 Spica_0073 e6d1d4762cb76e87a6efcc7cfbd1b266 388 Gene3D G3DSA:1.20.1090.10 189 388 1.6E-58 T 13-10-2018 Spica_2636 f94ed53b6c3a869df7e7e970eb65d720 271 Gene3D G3DSA:3.40.50.970 71 252 3.9E-21 T 13-10-2018 Spica_2636 f94ed53b6c3a869df7e7e970eb65d720 271 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 211 4.6E-24 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_2636 f94ed53b6c3a869df7e7e970eb65d720 271 SUPERFAMILY SSF52518 16 243 3.07E-52 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_0895 089d8bf175adef301167c7279dc85ea8 188 ProSitePatterns PS00893 Nudix box signature. 83 104 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spica_0895 089d8bf175adef301167c7279dc85ea8 188 Gene3D G3DSA:3.90.79.10 5 184 1.6E-42 T 13-10-2018 Spica_0895 089d8bf175adef301167c7279dc85ea8 188 SUPERFAMILY SSF55811 9 183 1.35E-38 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0895 089d8bf175adef301167c7279dc85ea8 188 Pfam PF00293 NUDIX domain 54 159 2.2E-12 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SUPERFAMILY SSF49265 125 205 3.61E-5 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SUPERFAMILY SSF51126 601 947 2.51E-43 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SMART SM00710 847 869 4400.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SMART SM00710 782 804 4300.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SMART SM00710 811 843 1900.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SMART SM00710 870 892 130.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 SMART SM00710 719 741 2300.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 Gene3D G3DSA:2.60.40.10 120 222 3.0E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0639 bb03a5b571362b3e680f1f0fd1a298eb 985 Gene3D G3DSA:2.160.20.10 599 979 4.0E-85 T 13-10-2018 IPR012334 Pectin lyase fold Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 9 419 5.9E-119 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 Gene3D G3DSA:3.40.50.800 339 433 2.9E-12 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 Gene3D G3DSA:3.30.930.10 3 335 2.5E-106 T 13-10-2018 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 Pfam PF13393 Histidyl-tRNA synthetase 12 324 7.3E-48 T 13-10-2018 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 5 434 26.474 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 PIRSF PIRSF001549 4 433 2.5E-123 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 Pfam PF03129 Anticodon binding domain 342 430 1.1E-6 T 13-10-2018 IPR004154 Anticodon-binding Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 SUPERFAMILY SSF55681 8 331 1.07E-80 T 13-10-2018 Spica_1334 81d397d9f2901d9b4e384f48d36bbd34 434 SUPERFAMILY SSF52954 341 416 6.13E-8 T 13-10-2018 Spica_1262 f63ee3f70fb5dec1a39e956a6b70e7d6 192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 186 1.8E-33 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Spica_1262 f63ee3f70fb5dec1a39e956a6b70e7d6 192 SUPERFAMILY SSF53323 3 190 8.63E-39 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_1262 f63ee3f70fb5dec1a39e956a6b70e7d6 192 Gene3D G3DSA:3.40.920.10 1 192 2.9E-42 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 Pfam PF08666 SAF domain 282 334 3.7E-10 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 Gene3D G3DSA:3.20.20.70 1 264 1.3E-106 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 Pfam PF03102 NeuB family 24 266 4.2E-102 T 13-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 4 331 6.4E-155 T 13-10-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|MetaCyc: PWY-6749|MetaCyc: PWY-7131 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 SUPERFAMILY SSF51269 272 334 7.53E-17 T 13-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 Gene3D G3DSA:3.90.1210.10 267 334 2.0E-21 T 13-10-2018 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 SUPERFAMILY SSF51569 2 290 7.81E-92 T 13-10-2018 Spica_0510 b96d8c9bc19c0b5077ea056592ce1cb5 334 SMART SM00858 280 334 3.0E-7 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 255 275 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 3.9E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 SUPERFAMILY SSF51735 33 292 8.95E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 Gene3D G3DSA:3.40.50.720 26 294 8.3E-63 T 13-10-2018 Spica_0306 fc773c366601b693957fdbe9cc7a5366 296 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 41 292 1.8E-48 T 13-10-2018 Spica_2372 66c23704f56e16cac300e69f37a4d700 301 SUPERFAMILY SSF89550 6 274 1.44E-40 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_2372 66c23704f56e16cac300e69f37a4d700 301 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 7 259 1.6E-37 T 13-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 Spica_2372 66c23704f56e16cac300e69f37a4d700 301 Pfam PF02811 PHP domain 6 171 2.4E-10 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_2372 66c23704f56e16cac300e69f37a4d700 301 Gene3D G3DSA:3.20.20.140 6 282 2.1E-65 T 13-10-2018 Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 SUPERFAMILY SSF52540 26 267 6.98E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 SMART SM00382 52 269 3.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 Gene3D G3DSA:3.40.50.300 27 279 5.7E-66 T 13-10-2018 Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 28 281 4.3E-112 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Spica_1712 a5c510357d56a45d9366d1162b15d01e 281 Pfam PF00005 ABC transporter 44 200 4.5E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 230 7.0E-45 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 15 600 5.6E-190 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 SUPERFAMILY SSF56519 54 249 1.02E-39 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 Gene3D G3DSA:3.90.1310.10 59 235 3.9E-41 T 13-10-2018 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 Gene3D G3DSA:3.30.1390.30 81 157 3.9E-41 T 13-10-2018 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 584 5.7E-76 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 Gene3D G3DSA:3.40.710.10 245 610 2.1E-103 T 13-10-2018 Spica_1386 69be5ee2eaec515808298afe276cee0d 624 SUPERFAMILY SSF56601 250 598 1.86E-93 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Spica_0372 a93198dbc91f48591395aaed14f49221 57 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 3 55 17.795 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0372 a93198dbc91f48591395aaed14f49221 57 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 57 1.7E-25 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0372 a93198dbc91f48591395aaed14f49221 57 Gene3D G3DSA:2.20.28.120 3 56 5.1E-21 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0372 a93198dbc91f48591395aaed14f49221 57 SUPERFAMILY SSF57829 5 55 3.24E-17 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spica_0372 a93198dbc91f48591395aaed14f49221 57 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0372 a93198dbc91f48591395aaed14f49221 57 Pfam PF00471 Ribosomal protein L33 10 55 1.6E-20 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1442 01381614b54e3aa656232dc2dd757688 398 Gene3D G3DSA:2.120.10.30 16 259 2.8E-6 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Spica_1442 01381614b54e3aa656232dc2dd757688 398 SUPERFAMILY SSF101898 61 248 1.2E-6 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 1.1E-29 T 13-10-2018 IPR000362 Fumarate lyase family Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.1E-29 T 13-10-2018 IPR000362 Fumarate lyase family Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.1E-29 T 13-10-2018 IPR000362 Fumarate lyase family Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 1.1E-29 T 13-10-2018 IPR000362 Fumarate lyase family Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 SUPERFAMILY SSF48557 5 458 4.24E-134 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Pfam PF00206 Lyase 8 301 6.4E-64 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 456 40.901 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Gene3D G3DSA:1.10.275.10 31 231 1.3E-173 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Gene3D G3DSA:1.20.200.10 121 453 1.3E-173 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 3.7E-58 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Pfam PF14698 Argininosuccinate lyase C-terminal 365 431 2.1E-19 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 Gene3D G3DSA:1.10.40.30 362 435 1.3E-173 T 13-10-2018 Spica_0888 8982fbb8bbe975ee849e8d4eeb707a8f 460 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 458 8.5E-175 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Spica_R0030 acf33238cc6e7112b7274dda62844180 411 ProSitePatterns PS01276 Peptidase family U32 signature. 170 188 - T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Spica_R0030 acf33238cc6e7112b7274dda62844180 411 Pfam PF01136 Peptidase family U32 76 310 9.0E-72 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 Pfam PF03193 RsgA GTPase 107 303 1.2E-35 T 13-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 SUPERFAMILY SSF52540 125 366 1.81E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 Gene3D G3DSA:3.40.50.300 110 302 2.0E-39 T 13-10-2018 Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 Gene3D G3DSA:1.10.40.50 304 394 2.7E-21 T 13-10-2018 Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 32 366 28.142 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Spica_2129 c09a81331bf84853d31a7b017f5571c3 396 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 88 358 3.9E-44 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 Spica_2610 00308072a49e4d87241414a556b6637a 96 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5 75 3.9E-23 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 Spica_2610 00308072a49e4d87241414a556b6637a 96 SMART SM00360 4 77 4.8E-31 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 Spica_2610 00308072a49e4d87241414a556b6637a 96 SUPERFAMILY SSF54928 3 95 9.67E-34 T 13-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 Spica_2610 00308072a49e4d87241414a556b6637a 96 Gene3D G3DSA:3.30.70.330 1 95 1.2E-32 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_1311 44e230f43c9403154904b7c703e8c521 263 Pfam PF03099 Biotin/lipoate A/B protein ligase family 100 222 7.5E-6 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Spica_1311 44e230f43c9403154904b7c703e8c521 263 SUPERFAMILY SSF55681 95 258 5.84E-28 T 13-10-2018 Spica_1311 44e230f43c9403154904b7c703e8c521 263 SUPERFAMILY SSF46785 22 75 5.45E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1311 44e230f43c9403154904b7c703e8c521 263 Pfam PF08279 HTH domain 22 74 5.3E-13 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_1311 44e230f43c9403154904b7c703e8c521 263 Gene3D G3DSA:1.10.10.10 16 77 3.2E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1311 44e230f43c9403154904b7c703e8c521 263 Gene3D G3DSA:3.30.930.10 95 263 2.6E-30 T 13-10-2018 Spica_1311 44e230f43c9403154904b7c703e8c521 263 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 98 259 6.6E-27 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_0801 f65a106610e5899e90779d88130df4f3 124 SUPERFAMILY SSF52172 3 122 2.99E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0801 f65a106610e5899e90779d88130df4f3 124 Gene3D G3DSA:3.40.50.12740 1 124 5.2E-37 T 13-10-2018 Spica_0801 f65a106610e5899e90779d88130df4f3 124 Pfam PF00072 Response regulator receiver domain 5 117 8.6E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0801 f65a106610e5899e90779d88130df4f3 124 SMART SM00448 3 117 3.5E-39 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 SUPERFAMILY SSF53850 15 277 1.63E-63 T 13-10-2018 Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 276 7.9E-54 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 Gene3D G3DSA:3.40.190.10 54 276 4.5E-56 T 13-10-2018 Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 SMART SM00079 51 278 4.0E-5 T 13-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 Gene3D G3DSA:3.40.190.10 138 236 4.5E-56 T 13-10-2018 Spica_2601 3b2ec25d6cea6a999c456110d9fe7276 281 SMART SM00062 51 279 1.1E-48 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 SUPERFAMILY SSF55874 2 209 1.44E-66 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 SMART SM00387 24 179 4.4E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 SUPERFAMILY SSF54211 232 482 1.74E-88 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 SUPERFAMILY SSF110942 504 618 8.89E-35 T 13-10-2018 IPR037196 HSP90, C-terminal domain Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Gene3D G3DSA:3.30.565.10 1 225 2.0E-76 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 22 159 6.7E-14 T 13-10-2018 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Gene3D G3DSA:1.20.120.790 486 618 4.9E-44 T 13-10-2018 IPR037196 HSP90, C-terminal domain Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 618 30.547 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PIRSF PIRSF002583 1 619 1.2E-211 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 13-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Pfam PF00183 Hsp90 protein 210 618 3.0E-119 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Gene3D G3DSA:3.30.230.80 230 397 1.8E-63 T 13-10-2018 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 Gene3D G3DSA:3.40.50.11260 398 484 5.4E-28 T 13-10-2018 Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 2 22 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 90 107 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 23 45 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 167 184 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 72 89 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 117 139 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0298 e83378fdb9ae2aac198ec2849e5d6a54 619 PRINTS PR00775 90kDa heat shock protein signature 185 203 4.2E-60 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 448 638 2.2E-46 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 Gene3D G3DSA:3.60.40.10 399 638 1.8E-57 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 Pfam PF13185 GAF domain 232 384 8.3E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 SUPERFAMILY SSF55781 218 395 4.14E-20 T 13-10-2018 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 SUPERFAMILY SSF81606 439 637 1.16E-7 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 Gene3D G3DSA:3.30.450.40 217 398 4.2E-19 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 SMART SM00331 421 638 7.3E-41 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1094 dd61cff97eb38beaf44b165efe9f3e71 639 SMART SM00065 232 394 9.5E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_2216 b9e19d6a9c5c1b9f63412329bea3dcc8 319 SUPERFAMILY SSF53822 28 301 1.45E-71 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2216 b9e19d6a9c5c1b9f63412329bea3dcc8 319 Gene3D G3DSA:3.40.50.2300 134 274 1.5E-104 T 13-10-2018 Spica_2216 b9e19d6a9c5c1b9f63412329bea3dcc8 319 Gene3D G3DSA:3.40.50.2300 33 291 1.5E-104 T 13-10-2018 Spica_2216 b9e19d6a9c5c1b9f63412329bea3dcc8 319 Pfam PF13407 Periplasmic binding protein domain 38 292 2.3E-47 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0788 ea07ba9324799245811e104524cdb19f 123 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 7 113 19.556 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spica_0788 ea07ba9324799245811e104524cdb19f 123 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 15 112 3.6E-28 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spica_0788 ea07ba9324799245811e104524cdb19f 123 Gene3D G3DSA:3.30.460.10 5 116 1.3E-29 T 13-10-2018 Spica_0788 ea07ba9324799245811e104524cdb19f 123 Pfam PF02410 Ribosomal silencing factor during starvation 16 112 1.4E-22 T 13-10-2018 Spica_0788 ea07ba9324799245811e104524cdb19f 123 SUPERFAMILY SSF81301 10 118 1.8E-27 T 13-10-2018 Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 SUPERFAMILY SSF55785 245 350 3.43E-8 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 Gene3D G3DSA:3.30.565.10 419 553 1.0E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 Gene3D G3DSA:3.30.450.20 250 413 2.8E-10 T 13-10-2018 Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 Pfam PF13188 PAS domain 238 270 1.6E-4 T 13-10-2018 IPR000014 PAS domain Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 SUPERFAMILY SSF55874 422 540 1.02E-11 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 Pfam PF07568 Histidine kinase 361 435 2.5E-24 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0832 9b9b633533b31e6129109955ca6bbb81 555 Pfam PF16927 N-terminal 7TM region of histidine kinase 11 233 1.1E-38 T 13-10-2018 IPR031621 Histidine kinase, N-terminal 7TM region Spica_2815 f348145ffced42634d45f0aed2381f77 362 Pfam PF13407 Periplasmic binding protein domain 38 314 6.3E-65 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2815 f348145ffced42634d45f0aed2381f77 362 Gene3D G3DSA:3.40.50.2300 38 336 2.3E-135 T 13-10-2018 Spica_2815 f348145ffced42634d45f0aed2381f77 362 SUPERFAMILY SSF53822 34 350 1.99E-70 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2815 f348145ffced42634d45f0aed2381f77 362 Gene3D G3DSA:3.40.50.2300 140 357 2.3E-135 T 13-10-2018 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 SUPERFAMILY SSF143034 2 62 6.28E-20 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 65 4.6E-25 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 Pfam PF01632 Ribosomal protein L35 2 60 3.6E-22 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.545 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.4E-19 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.4E-19 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.4E-19 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Spica_1698 4fee3eb3876ef9bd02bce4705407472d 66 Gene3D G3DSA:2.40.50.530 1 65 1.0E-21 T 13-10-2018 Spica_1406 07753024182935f484659b05e876cba8 62 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 56 20.852 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1406 07753024182935f484659b05e876cba8 62 Pfam PF01783 Ribosomal L32p protein family 2 56 3.0E-25 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1406 07753024182935f484659b05e876cba8 62 SUPERFAMILY SSF57829 1 56 1.28E-20 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Spica_1406 07753024182935f484659b05e876cba8 62 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 4.1E-27 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0211 c0558616108dd6df66be25f8536ec7f3 306 Gene3D G3DSA:1.10.3720.10 60 304 2.8E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0211 c0558616108dd6df66be25f8536ec7f3 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 295 8.8E-7 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0211 c0558616108dd6df66be25f8536ec7f3 306 SUPERFAMILY SSF161098 19 301 9.16E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 Gene3D G3DSA:3.40.50.300 182 373 1.4E-61 T 13-10-2018 Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 SMART SM00382 186 387 9.5E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 280 8.0E-55 T 13-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 SUPERFAMILY SSF52540 185 374 7.51E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 Gene3D G3DSA:1.20.120.1380 132 376 1.4E-61 T 13-10-2018 Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 Pfam PF00448 SRP54-type protein, GTPase domain 187 380 3.2E-37 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_1524 0c53b15ffbdd1be7f4b5622143908ff1 405 SMART SM00962 187 385 7.3E-47 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 330 404 2.9E-29 T 13-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 PRINTS PR00956 Flagellar motor switch protein FliN signature 350 366 1.9E-27 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 PRINTS PR00956 Flagellar motor switch protein FliN signature 366 379 1.9E-27 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 PRINTS PR00956 Flagellar motor switch protein FliN signature 333 349 1.9E-27 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 PRINTS PR00956 Flagellar motor switch protein FliN signature 379 394 1.9E-27 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 334 403 1.8E-23 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 Gene3D G3DSA:2.30.330.10 321 413 4.6E-34 T 13-10-2018 IPR036429 SpoA-like superfamily Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 Gene3D G3DSA:3.40.1550.10 34 216 3.6E-23 T 13-10-2018 IPR028976 CheC-like superfamily Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 SUPERFAMILY SSF103039 34 214 2.35E-23 T 13-10-2018 IPR028976 CheC-like superfamily Spica_1531 b37bb1e2dd213295b6e8cae9d0ecf4d5 413 SUPERFAMILY SSF101801 331 410 7.06E-23 T 13-10-2018 IPR036429 SpoA-like superfamily Spica_1249 985b842e86ff54c863da27a6940587fa 783 SMART SM00487 66 273 3.4E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1249 985b842e86ff54c863da27a6940587fa 783 Gene3D G3DSA:3.40.50.300 287 443 4.1E-24 T 13-10-2018 Spica_1249 985b842e86ff54c863da27a6940587fa 783 Pfam PF00271 Helicase conserved C-terminal domain 303 409 1.7E-13 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1249 985b842e86ff54c863da27a6940587fa 783 SUPERFAMILY SSF52540 77 420 8.17E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1249 985b842e86ff54c863da27a6940587fa 783 Pfam PF09369 Domain of unknown function (DUF1998) 684 760 4.8E-16 T 13-10-2018 IPR018973 DEAD/DEAH-box helicase, putative Spica_1249 985b842e86ff54c863da27a6940587fa 783 Pfam PF00270 DEAD/DEAH box helicase 73 244 1.9E-23 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1249 985b842e86ff54c863da27a6940587fa 783 SMART SM00490 327 409 1.9E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1249 985b842e86ff54c863da27a6940587fa 783 Gene3D G3DSA:3.40.50.300 47 260 8.0E-45 T 13-10-2018 Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 SUPERFAMILY SSF52540 3 227 3.88E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 SUPERFAMILY SSF52540 244 471 1.26E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 Pfam PF00005 ABC transporter 18 168 6.1E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 SMART SM00382 27 215 2.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 SMART SM00382 276 470 5.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 Gene3D G3DSA:3.40.50.300 1 238 3.2E-55 T 13-10-2018 Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 Pfam PF00005 ABC transporter 268 421 3.1E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0816 feb159c1a4e4583fcffa3ef0eb769e7f 491 Gene3D G3DSA:3.40.50.300 241 486 3.3E-42 T 13-10-2018 Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 SMART SM00813 290 486 7.1E-55 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 Gene3D G3DSA:3.20.20.80 18 377 1.8E-204 T 13-10-2018 Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 SUPERFAMILY SSF51011 357 493 8.27E-24 T 13-10-2018 Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 SUPERFAMILY SSF51445 17 371 4.55E-103 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 290 486 4.6E-35 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Spica_0716 b29f14ea78a7bdb259eda23d718244c1 497 Gene3D G3DSA:2.60.40.1180 6 491 1.8E-204 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_1366 81e4b2547527834a1a6bc96796d90d18 312 SMART SM00028 157 190 71.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1366 81e4b2547527834a1a6bc96796d90d18 312 SMART SM00028 123 156 0.058 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1366 81e4b2547527834a1a6bc96796d90d18 312 SUPERFAMILY SSF48452 11 193 7.87E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1366 81e4b2547527834a1a6bc96796d90d18 312 Gene3D G3DSA:1.25.40.10 3 309 4.3E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2611 19ea38d926912906712512d403e53968 717 Pfam PF08376 Nitrate and nitrite sensing 53 208 4.3E-18 T 13-10-2018 IPR013587 Nitrate/nitrite sensing protein Spica_2611 19ea38d926912906712512d403e53968 717 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 491 636 6.5E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2611 19ea38d926912906712512d403e53968 717 Gene3D G3DSA:1.20.1480.50 283 386 6.5E-10 T 13-10-2018 Spica_2611 19ea38d926912906712512d403e53968 717 SMART SM00304 326 380 1.9E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2611 19ea38d926912906712512d403e53968 717 SMART SM00283 423 670 2.2E-51 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2611 19ea38d926912906712512d403e53968 717 Gene3D G3DSA:1.10.287.950 412 665 1.9E-46 T 13-10-2018 Spica_2611 19ea38d926912906712512d403e53968 717 SUPERFAMILY SSF58104 348 670 8.63E-49 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:1.10.287.610 2 53 1.5E-7 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SUPERFAMILY SSF52113 554 633 2.29E-16 T 13-10-2018 IPR036420 BRCT domain superfamily Spica_1480 be8a5d5e1eb126143f4151777186d521 665 PIRSF PIRSF001604 1 636 5.7E-159 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:2.40.50.140 283 355 9.3E-16 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SUPERFAMILY SSF56091 3 283 7.61E-64 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 98 127 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:1.10.150.20 398 468 3.2E-11 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SMART SM00532 1 414 1.4E-98 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SUPERFAMILY SSF47781 373 531 4.45E-31 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_1480 be8a5d5e1eb126143f4151777186d521 665 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 9 627 1.3E-157 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:3.40.50.10190 546 633 1.7E-23 T 13-10-2018 IPR036420 BRCT domain superfamily Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:3.30.470.30 60 223 3.5E-50 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 281 7.7E-47 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SMART SM00292 555 634 7.3E-11 T 13-10-2018 IPR001357 BRCT domain Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Pfam PF14520 Helix-hairpin-helix domain 482 529 5.0E-7 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 302 357 2.7E-14 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Hamap MF_01588 DNA ligase [ligA]. 1 631 39.033 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:3.30.1490.70 68 281 3.5E-50 T 13-10-2018 Spica_1480 be8a5d5e1eb126143f4151777186d521 665 SUPERFAMILY SSF50249 285 357 9.42E-13 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 555 631 1.9E-12 T 13-10-2018 IPR001357 BRCT domain Spica_1480 be8a5d5e1eb126143f4151777186d521 665 Gene3D G3DSA:1.10.150.20 480 532 1.9E-9 T 13-10-2018 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 PIRSF PIRSF000151 1 423 1.7E-162 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 422 38.031 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 12 412 2.8E-134 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 Gene3D G3DSA:3.40.309.10 224 380 1.7E-154 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 Pfam PF00171 Aldehyde dehydrogenase family 12 279 6.3E-11 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 Gene3D G3DSA:3.40.605.10 16 417 1.7E-154 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Spica_0840 1fe856ef1f0ad9e8131a0eb9ed4c7b64 423 SUPERFAMILY SSF53720 9 422 6.41E-104 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Gene3D G3DSA:3.30.450.20 171 294 8.7E-19 T 13-10-2018 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Pfam PF00672 HAMP domain 317 363 6.0E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Pfam PF02743 Cache domain 44 278 2.8E-35 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Pfam PF06580 Histidine kinase 381 459 8.3E-25 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Gene3D G3DSA:3.30.565.10 439 592 2.1E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 Gene3D G3DSA:1.10.287.130 314 438 2.7E-10 T 13-10-2018 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 SUPERFAMILY SSF158472 317 365 1.26E-9 T 13-10-2018 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 SMART SM00304 316 368 3.1E-13 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2147 6b9b357150a8b61a7cb09833ecfd1364 596 SUPERFAMILY SSF55874 435 588 6.42E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1177 e459fe9c8517af1ecaff4b9dedec79fd 370 Pfam PF01594 AI-2E family transporter 10 348 5.9E-42 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like Spica_1305 3852220c4d570c1c0ecd221506597268 321 PIRSF PIRSF027386 1 316 7.1E-86 T 13-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type Spica_1305 3852220c4d570c1c0ecd221506597268 321 Gene3D G3DSA:3.40.190.10 102 211 1.0E-81 T 13-10-2018 Spica_1305 3852220c4d570c1c0ecd221506597268 321 SUPERFAMILY SSF53850 50 298 1.28E-28 T 13-10-2018 Spica_1305 3852220c4d570c1c0ecd221506597268 321 Pfam PF13379 NMT1-like family 76 246 1.9E-12 T 13-10-2018 Spica_1305 3852220c4d570c1c0ecd221506597268 321 Gene3D G3DSA:3.40.190.10 27 312 1.0E-81 T 13-10-2018 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 Hamap MF_00456 Glutamate 5-kinase [proB]. 10 264 34.37 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 SUPERFAMILY SSF53633 10 262 1.27E-63 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 TIGRFAM TIGR01027 proB: glutamate 5-kinase 11 263 9.0E-89 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 ProSitePatterns PS00902 Glutamate 5-kinase signature. 212 229 - T 13-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PIRSF PIRSF000729 5 267 4.1E-93 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 3.7E-46 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 3.7E-46 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 3.7E-46 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PRINTS PR00474 Glutamate 5-kinase family signature 214 234 3.7E-46 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 3.7E-46 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 Gene3D G3DSA:3.40.1160.10 3 265 7.2E-79 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0841 1f974d25d611b154ffa91fc2c6f71562 267 Pfam PF00696 Amino acid kinase family 11 239 1.1E-44 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 SUPERFAMILY SSF52172 4 113 1.71E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2766 f8fa43ce6490d2754584434be26593f7 372 Pfam PF01339 CheB methylesterase 182 361 4.8E-61 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 5 366 37.027 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 Gene3D G3DSA:3.40.50.180 172 369 1.5E-69 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_2766 f8fa43ce6490d2754584434be26593f7 372 PIRSF PIRSF000876 2 370 3.4E-133 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 Pfam PF00072 Response regulator receiver domain 7 114 4.7E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 Gene3D G3DSA:3.40.50.2300 2 139 3.3E-29 T 13-10-2018 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 SMART SM00448 5 121 7.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2766 f8fa43ce6490d2754584434be26593f7 372 SUPERFAMILY SSF52738 177 366 4.05E-65 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 SMART SM00065 22 189 2.5E-12 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 SMART SM00471 200 364 1.5E-8 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 Pfam PF01590 GAF domain 22 179 4.1E-15 T 13-10-2018 IPR003018 GAF domain GO:0005515 Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 SUPERFAMILY SSF55781 7 196 1.37E-28 T 13-10-2018 Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 SUPERFAMILY SSF109604 201 395 6.57E-31 T 13-10-2018 Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 Gene3D G3DSA:1.10.3210.10 185 407 9.8E-66 T 13-10-2018 Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 Gene3D G3DSA:3.30.450.40 2 184 1.8E-37 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_1704 d8e157e11003abdc900d9f1dc7d73e2f 409 Pfam PF01966 HD domain 206 354 1.1E-19 T 13-10-2018 IPR006674 HD domain Spica_0401 99b4c8dda525e02cdf525aaabc9eb471 120 Gene3D G3DSA:3.30.420.100 6 120 1.9E-41 T 13-10-2018 Spica_0401 99b4c8dda525e02cdf525aaabc9eb471 120 SUPERFAMILY SSF53137 8 118 1.33E-47 T 13-10-2018 Spica_0401 99b4c8dda525e02cdf525aaabc9eb471 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 7 120 27.478 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0401 99b4c8dda525e02cdf525aaabc9eb471 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 8 120 2.1E-40 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0401 99b4c8dda525e02cdf525aaabc9eb471 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 7 120 8.7E-44 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2016 e3b1f8248d32902f9251e87322427980 103 SUPERFAMILY SSF54736 18 102 9.94E-30 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_2016 e3b1f8248d32902f9251e87322427980 103 Gene3D G3DSA:3.30.1390.10 2 103 6.4E-41 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_2016 e3b1f8248d32902f9251e87322427980 103 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 21 98 1.0E-33 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 Spica_2016 e3b1f8248d32902f9251e87322427980 103 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 12 98 25.265 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS Spica_0625 9c3c0e33f478fac762c319c456118374 318 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 203 2.1E-76 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spica_0625 9c3c0e33f478fac762c319c456118374 318 Pfam PF01081 KDPG and KHG aldolase 7 199 2.1E-68 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spica_0625 9c3c0e33f478fac762c319c456118374 318 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 13-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spica_0625 9c3c0e33f478fac762c319c456118374 318 SUPERFAMILY SSF51569 2 204 2.38E-64 T 13-10-2018 Spica_0625 9c3c0e33f478fac762c319c456118374 318 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 13-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Spica_0625 9c3c0e33f478fac762c319c456118374 318 Gene3D G3DSA:3.20.20.70 2 208 5.1E-75 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Gene3D G3DSA:3.30.300.180 2 82 1.4E-15 T 13-10-2018 IPR038454 DnaA, N-terminal domain superfamily Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 SUPERFAMILY SSF48295 361 466 2.62E-36 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 SMART SM00382 163 292 4.6E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 SMART SM00760 374 443 2.3E-40 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 164 184 5.2E-46 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 195 209 5.2E-46 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 227 241 5.2E-46 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 424 443 5.2E-46 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 261 288 5.2E-46 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 ProSitePatterns PS01008 DnaA protein signature. 424 443 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 7 465 31.557 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 10 464 4.5E-160 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Gene3D G3DSA:3.40.50.300 114 294 6.4E-49 T 13-10-2018 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Pfam PF11638 DnaA N-terminal domain 9 66 4.9E-8 T 13-10-2018 IPR024633 DnaA N-terminal domain Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Gene3D G3DSA:1.10.8.60 296 365 2.2E-24 T 13-10-2018 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 375 443 6.1E-31 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 SUPERFAMILY SSF52540 132 341 1.2E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Pfam PF00308 Bacterial dnaA protein 131 346 1.6E-91 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Spica_0001 3342e0f9ec0bcbf47f0e216401c42a65 471 Gene3D G3DSA:1.10.1750.10 366 468 1.2E-35 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Spica_2225 7e4d1282cd289b99ea93f261b989e336 344 Pfam PF13528 Glycosyl transferase family 1 1 134 4.2E-18 T 13-10-2018 Spica_2225 7e4d1282cd289b99ea93f261b989e336 344 Pfam PF13528 Glycosyl transferase family 1 208 291 3.9E-15 T 13-10-2018 Spica_2225 7e4d1282cd289b99ea93f261b989e336 344 SUPERFAMILY SSF53756 1 279 2.47E-19 T 13-10-2018 Spica_2225 7e4d1282cd289b99ea93f261b989e336 344 Gene3D G3DSA:3.40.50.2000 202 301 4.1E-12 T 13-10-2018 Spica_1560 2228cc60dfb8aa0ea061ab3ec1e95499 368 Pfam PF02277 Phosphoribosyltransferase 3 358 7.0E-114 T 13-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Spica_1560 2228cc60dfb8aa0ea061ab3ec1e95499 368 SUPERFAMILY SSF52733 3 359 4.45E-103 T 13-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Spica_1560 2228cc60dfb8aa0ea061ab3ec1e95499 368 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4 358 2.4E-113 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Spica_1560 2228cc60dfb8aa0ea061ab3ec1e95499 368 Gene3D G3DSA:3.40.50.10210 44 341 1.0E-115 T 13-10-2018 Spica_1560 2228cc60dfb8aa0ea061ab3ec1e95499 368 Gene3D G3DSA:1.10.1610.10 12 358 1.0E-115 T 13-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 SUPERFAMILY SSF51905 6 316 2.71E-49 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 3.1E-32 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.1E-32 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.1E-32 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 3.1E-32 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 3.1E-32 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 Gene3D G3DSA:3.50.50.60 8 301 4.9E-99 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0972 14362289e1ac3175cf87d292e190ea61 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 298 7.6E-43 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 Gene3D G3DSA:3.50.50.60 119 244 4.9E-99 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0972 14362289e1ac3175cf87d292e190ea61 411 Gene3D G3DSA:3.40.30.10 313 409 2.4E-6 T 13-10-2018 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 SUPERFAMILY SSF52833 339 407 1.72E-6 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0972 14362289e1ac3175cf87d292e190ea61 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 2.4E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0818 fff3b04b5f4668dbe99fd0424f334433 295 Pfam PF13407 Periplasmic binding protein domain 31 281 2.9E-63 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0818 fff3b04b5f4668dbe99fd0424f334433 295 Gene3D G3DSA:3.40.50.2300 34 282 1.0E-90 T 13-10-2018 Spica_0818 fff3b04b5f4668dbe99fd0424f334433 295 SUPERFAMILY SSF53822 15 294 3.68E-88 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0818 fff3b04b5f4668dbe99fd0424f334433 295 Gene3D G3DSA:3.40.50.2300 129 263 1.0E-90 T 13-10-2018 Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 Hamap MF_00165 Thymidylate kinase [tmk]. 5 214 19.606 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 ProSitePatterns PS01331 Thymidylate kinase signature. 106 118 - T 13-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 SUPERFAMILY SSF52540 6 212 4.5E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 3 206 1.9E-38 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 Gene3D G3DSA:3.40.50.300 4 214 8.1E-49 T 13-10-2018 Spica_1345 cc3604b1bc36707c11e5772ed9b41a00 218 Pfam PF02223 Thymidylate kinase 9 205 8.6E-37 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 SUPERFAMILY SSF53850 72 560 3.26E-92 T 13-10-2018 Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 120 481 2.2E-60 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 Gene3D G3DSA:3.40.190.10 90 537 1.1E-104 T 13-10-2018 Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 PIRSF PIRSF002741 34 564 4.2E-71 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 Gene3D G3DSA:3.10.105.10 327 530 1.1E-104 T 13-10-2018 Spica_2105 945de9246fb0828099090f5ef8aaaf78 580 Gene3D G3DSA:3.90.76.10 108 239 1.1E-104 T 13-10-2018 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 1 416 3.4E-118 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 Gene3D G3DSA:1.10.240.10 222 325 7.8E-32 T 13-10-2018 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 SUPERFAMILY SSF55174 302 416 5.49E-9 T 13-10-2018 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 SUPERFAMILY SSF52374 4 317 8.19E-98 T 13-10-2018 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 417 41.17 T 13-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 Pfam PF00579 tRNA synthetases class I (W and Y) 29 319 1.3E-79 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 5.7E-27 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 5.7E-27 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 5.7E-27 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 5.7E-27 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1931 af825afa7f0a2934a10446223d2457e1 418 Gene3D G3DSA:3.40.50.620 1 221 1.4E-82 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1931 af825afa7f0a2934a10446223d2457e1 418 Gene3D G3DSA:3.10.290.10 326 416 9.2E-13 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Spica_0630 9bd4c60b2434e64bc253ea4e174b7f90 478 Hamap MF_00675 Uronate isomerase [uxaC]. 2 475 47.757 T 13-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 Spica_0630 9bd4c60b2434e64bc253ea4e174b7f90 478 SUPERFAMILY SSF51556 2 473 5.78E-173 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_0630 9bd4c60b2434e64bc253ea4e174b7f90 478 Pfam PF02614 Glucuronate isomerase 1 473 7.3E-212 T 13-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 Spica_0630 9bd4c60b2434e64bc253ea4e174b7f90 478 Gene3D G3DSA:3.20.20.140 7 473 7.1E-197 T 13-10-2018 Spica_0630 9bd4c60b2434e64bc253ea4e174b7f90 478 Gene3D G3DSA:1.10.2020.10 46 136 7.1E-197 T 13-10-2018 Spica_2821 02d720960675380370ec0c3b479f8633 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 408 1.2E-64 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2821 02d720960675380370ec0c3b479f8633 458 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 430 457 - T 13-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Spica_2821 02d720960675380370ec0c3b479f8633 458 Pfam PF01554 MatE 21 184 6.4E-31 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2821 02d720960675380370ec0c3b479f8633 458 Pfam PF01554 MatE 247 405 2.4E-18 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2821 02d720960675380370ec0c3b479f8633 458 PIRSF PIRSF006603 1 454 1.2E-80 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 127 144 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 117 131 9.3E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 113 9.3E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 132 145 9.3E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 Pfam PF00364 Biotin-requiring enzyme 97 169 7.3E-18 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 4 171 3.7E-38 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 SUPERFAMILY SSF51230 97 170 1.07E-20 T 13-10-2018 IPR011053 Single hybrid motif Spica_2041 70bfc521a552f37ee3a16481579fbdf3 173 Gene3D G3DSA:2.40.50.100 92 170 2.9E-26 T 13-10-2018 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 SUPERFAMILY SSF52096 32 304 4.4E-92 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 136 4.7E-51 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 Gene3D G3DSA:3.90.226.10 2 306 4.9E-107 T 13-10-2018 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 5 307 9.9E-122 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 304 43.924 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 76 87 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 101 119 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 122 138 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 185 194 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 141 154 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_2044 ecdc3dd6e3f4e1541a8625c9aa4936ec 309 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 157 170 3.3E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Spica_1043 f363bcced16c05021c638842b5fa3146 359 Gene3D G3DSA:2.130.10.10 110 357 2.8E-6 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_1043 f363bcced16c05021c638842b5fa3146 359 SUPERFAMILY SSF50998 112 310 1.88E-11 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 174 3.2E-41 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 SMART SM00278 108 127 0.2 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 SMART SM00278 73 92 12.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 Gene3D G3DSA:1.10.150.20 67 136 1.3E-22 T 13-10-2018 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 SUPERFAMILY SSF50249 1 63 1.43E-11 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 Pfam PF14520 Helix-hairpin-helix domain 72 129 3.3E-16 T 13-10-2018 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 187 25.699 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 Pfam PF01330 RuvA N terminal domain 1 62 1.1E-11 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 Gene3D G3DSA:2.40.50.140 1 66 4.9E-15 T 13-10-2018 Spica_1341 b31e714a585c8a9299e336b5775c53fd 232 SUPERFAMILY SSF47781 66 134 3.56E-18 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 53 2.5E-22 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 128 6.0E-18 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 129 25.702 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 3.4E-50 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 Gene3D G3DSA:3.30.1390.10 58 129 1.8E-31 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 129 5.7E-29 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 SUPERFAMILY SSF48300 4 64 1.23E-18 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 SUPERFAMILY SSF54736 57 128 1.13E-23 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_0378 3acf84d899f33ce6bb42cf83513a3b23 129 Gene3D G3DSA:1.20.5.710 4 57 3.0E-24 T 13-10-2018 Spica_2416 0e71ce963478783a1e8bb4962192c91c 217 Pfam PF00551 Formyl transferase 18 204 9.9E-50 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2416 0e71ce963478783a1e8bb4962192c91c 217 SUPERFAMILY SSF53328 18 208 2.62E-48 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Spica_2416 0e71ce963478783a1e8bb4962192c91c 217 Gene3D G3DSA:3.40.50.170 3 215 1.8E-68 T 13-10-2018 Spica_2416 0e71ce963478783a1e8bb4962192c91c 217 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 17 211 2.8E-57 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Spica_2416 0e71ce963478783a1e8bb4962192c91c 217 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 17 212 29.471 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 590 5.2E-10 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Gene3D G3DSA:1.20.1480.50 278 371 7.2E-12 T 13-10-2018 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Pfam PF00672 HAMP domain 315 361 1.1E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 SUPERFAMILY SSF55874 463 590 9.95E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 SMART SM00387 472 593 6.4E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 SUPERFAMILY SSF158472 315 365 5.75E-9 T 13-10-2018 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Gene3D G3DSA:3.30.450.20 199 233 7.9E-8 T 13-10-2018 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Pfam PF06580 Histidine kinase 379 457 1.4E-25 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Pfam PF02743 Cache domain 38 275 2.1E-29 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Gene3D G3DSA:3.30.565.10 448 592 1.6E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 SMART SM00304 314 366 4.1E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2213 b814e5294bcfd3c0b827c8443f88de08 594 Gene3D G3DSA:3.30.450.20 139 198 7.9E-8 T 13-10-2018 Spica_0042 f15e546a4371c182a409244cfd80b581 171 SUPERFAMILY SSF158397 64 170 4.84E-27 T 13-10-2018 IPR024042 TM1646-like domain superfamily Spica_0042 f15e546a4371c182a409244cfd80b581 171 Pfam PF03885 Protein of unknown function (DUF327) 26 170 1.4E-31 T 13-10-2018 IPR005585 Protein of unknown function DUF327 Spica_0042 f15e546a4371c182a409244cfd80b581 171 Gene3D G3DSA:1.20.120.490 53 171 7.3E-30 T 13-10-2018 IPR024042 TM1646-like domain superfamily Spica_1757 5027d9a979989dcfe8bbaaf664d88229 107 SUPERFAMILY SSF159894 6 87 2.04E-13 T 13-10-2018 Spica_1781 5027d9a979989dcfe8bbaaf664d88229 107 SUPERFAMILY SSF159894 6 87 2.04E-13 T 13-10-2018 Spica_2560 e82511e0872275396e31e3a469718f3a 475 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 13 444 5.9E-145 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 Gene3D G3DSA:3.40.50.300 183 360 4.4E-52 T 13-10-2018 Spica_2560 e82511e0872275396e31e3a469718f3a 475 Gene3D G3DSA:3.40.50.300 8 177 1.8E-39 T 13-10-2018 Spica_2560 e82511e0872275396e31e3a469718f3a 475 PIRSF PIRSF006485 11 451 1.0E-141 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 Pfam PF01926 50S ribosome-binding GTPase 189 306 3.2E-26 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 Pfam PF01926 50S ribosome-binding GTPase 15 128 4.0E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 Hamap MF_00195 GTPase Der [der]. 12 447 32.658 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 SUPERFAMILY SSF52540 146 445 1.67E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2560 e82511e0872275396e31e3a469718f3a 475 SUPERFAMILY SSF52540 14 187 1.65E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2560 e82511e0872275396e31e3a469718f3a 475 Gene3D G3DSA:3.30.300.20 364 447 9.4E-21 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_2560 e82511e0872275396e31e3a469718f3a 475 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 365 444 1.7E-22 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like Spica_2560 e82511e0872275396e31e3a469718f3a 475 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 186 353 1.3E-34 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 162 1.3E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 189 209 1.4E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_2560 e82511e0872275396e31e3a469718f3a 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 1.4E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 Gene3D G3DSA:3.30.70.141 1 147 2.6E-59 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 32.888 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 SUPERFAMILY SSF54919 1 146 1.13E-56 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 3.8E-39 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 3.8E-39 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 3.8E-39 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 3.8E-39 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 3.8E-39 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 SMART SM00562 1 138 7.8E-79 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 13-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_0493 963efbd02963d0ea30cefafe0e7aba78 147 Pfam PF00334 Nucleoside diphosphate kinase 2 135 1.2E-53 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 SMART SM00382 33 228 6.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 Pfam PF00005 ABC transporter 24 172 5.3E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 Gene3D G3DSA:3.40.50.300 4 246 2.3E-75 T 13-10-2018 Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 PIRSF PIRSF039085 5 247 2.0E-114 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 Spica_2504 b921c12f1a770d0879ef157970a9ca9e 247 SUPERFAMILY SSF52540 8 242 3.04E-79 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0450 f36ed85593701569f7c14eafd334021e 984 SUPERFAMILY SSF56672 580 984 1.89E-152 T 13-10-2018 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 196 284 3.8E-28 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SMART SM00474 392 576 2.8E-20 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SMART SM00475 6 286 4.1E-111 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:1.20.1060.10 601 714 2.4E-37 T 13-10-2018 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SUPERFAMILY SSF88723 4 195 5.15E-45 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0450 f36ed85593701569f7c14eafd334021e 984 SUPERFAMILY SSF47807 196 304 2.24E-27 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Spica_0450 f36ed85593701569f7c14eafd334021e 984 Pfam PF01612 3'-5' exonuclease 392 575 3.6E-23 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SUPERFAMILY SSF53098 395 576 5.15E-34 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0450 f36ed85593701569f7c14eafd334021e 984 TIGRFAM TIGR00593 pola: DNA polymerase I 8 984 1.2E-290 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:3.30.420.10 390 599 3.4E-55 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SMART SM00482 742 948 1.7E-119 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Pfam PF00476 DNA polymerase family A 608 982 5.5E-154 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 194 1.3E-43 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:1.10.150.20 199 271 6.4E-85 T 13-10-2018 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 786 799 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 711 733 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 810 835 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 847 858 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 901 917 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 734 749 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 756 779 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 869 880 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 PRINTS PR00868 DNA-polymerase family A (pol I) signature 931 944 2.0E-76 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:3.30.70.370 718 980 5.3E-114 T 13-10-2018 Spica_0450 f36ed85593701569f7c14eafd334021e 984 SMART SM00279 198 233 5.3E-13 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Spica_0450 f36ed85593701569f7c14eafd334021e 984 ProSitePatterns PS00447 DNA polymerase family A signature. 810 829 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:1.10.150.20 765 908 5.3E-114 T 13-10-2018 Spica_0450 f36ed85593701569f7c14eafd334021e 984 Gene3D G3DSA:3.40.50.1010 9 282 6.4E-85 T 13-10-2018 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 SUPERFAMILY SSF81296 293 383 6.44E-12 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 SMART SM00642 425 830 2.0E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Gene3D G3DSA:2.60.40.1180 846 933 6.1E-9 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 SUPERFAMILY SSF49452 69 181 6.54E-11 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 SUPERFAMILY SSF51445 414 839 5.98E-101 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 295 379 8.1E-10 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Gene3D G3DSA:2.60.40.10 284 396 2.2E-19 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Gene3D G3DSA:2.60.40.1110 69 180 5.4E-14 T 13-10-2018 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Pfam PF03714 Bacterial pullanase-associated domain 73 176 5.1E-12 T 13-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Pfam PF00128 Alpha amylase, catalytic domain 450 551 8.8E-10 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_0069 d5d6126a9b4ac1c132f1801329b2d420 933 Gene3D G3DSA:3.20.20.80 403 845 1.2E-153 T 13-10-2018 Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 PIRSF PIRSF005243 1 406 2.7E-110 T 13-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 SUPERFAMILY SSF52218 257 401 1.73E-29 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 Gene3D G3DSA:3.60.15.10 1 251 5.7E-78 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 Pfam PF00753 Metallo-beta-lactamase superfamily 35 147 1.8E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 SUPERFAMILY SSF56281 5 290 1.0E-41 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 Gene3D G3DSA:3.40.50.360 260 406 2.4E-28 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0878 35d4ed14fee8eb104bb7240735906c81 406 SMART SM00849 34 231 1.8E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0827 a268b95796913f68d1433cd3ae386a70 435 Gene3D G3DSA:3.40.190.10 51 379 9.8E-69 T 13-10-2018 Spica_0827 a268b95796913f68d1433cd3ae386a70 435 Gene3D G3DSA:3.40.190.10 147 416 9.8E-69 T 13-10-2018 Spica_0827 a268b95796913f68d1433cd3ae386a70 435 SUPERFAMILY SSF53850 34 434 1.09E-57 T 13-10-2018 Spica_0827 a268b95796913f68d1433cd3ae386a70 435 Pfam PF01547 Bacterial extracellular solute-binding protein 45 351 1.3E-26 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 Gene3D G3DSA:2.10.109.10 110 240 2.0E-23 T 13-10-2018 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 25 234 1.5E-25 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 ProSitePatterns PS00760 Signal peptidases I lysine active site. 130 142 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 SUPERFAMILY SSF51306 40 240 4.92E-31 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 Pfam PF10502 Signal peptidase, peptidase S26 112 226 1.0E-7 T 13-10-2018 IPR019533 Peptidase S26 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 41 57 3.8E-13 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 140 3.8E-13 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1301 b097b317634bdfe1e7115ab92a5d18e7 240 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 194 213 3.8E-13 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 1.1E-24 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 SUPERFAMILY SSF51735 3 154 8.57E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 Gene3D G3DSA:3.40.50.720 4 331 5.9E-89 T 13-10-2018 Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 244 9.7E-13 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 Gene3D G3DSA:3.30.360.10 130 350 5.9E-89 T 13-10-2018 Spica_2851 0e9a2987ce6af931f2e043db5e172ffb 357 SUPERFAMILY SSF55347 128 309 1.11E-30 T 13-10-2018 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 Gene3D G3DSA:2.40.420.20 287 353 5.6E-56 T 13-10-2018 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 SUPERFAMILY SSF111369 63 281 2.09E-31 T 13-10-2018 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 Gene3D G3DSA:2.40.30.170 62 286 5.6E-56 T 13-10-2018 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 279 4.1E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 Gene3D G3DSA:1.10.287.470 107 166 5.6E-56 T 13-10-2018 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 355 1.7E-51 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Spica_2024 ab4032f5cdf002e9e9628964c8516c2d 357 Gene3D G3DSA:2.40.50.100 73 205 5.6E-56 T 13-10-2018 Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 Gene3D G3DSA:3.30.2130.30 6 245 3.2E-100 T 13-10-2018 Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 Pfam PF01170 Putative RNA methylase family UPF0020 162 274 2.2E-28 T 13-10-2018 IPR000241 Putative RNA methylase domain Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 Pfam PF01170 Putative RNA methylase family UPF0020 307 386 4.7E-10 T 13-10-2018 IPR000241 Putative RNA methylase domain Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 SUPERFAMILY SSF53335 141 390 5.35E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 13-10-2018 IPR000241 Putative RNA methylase domain Spica_0583 47a1c203787c2e17e3867fd691b1942d 394 Gene3D G3DSA:3.40.50.150 160 385 3.2E-100 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 SUPERFAMILY SSF52821 452 556 2.49E-22 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 2.5E-16 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 290 2.5E-16 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.5E-16 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 2.5E-16 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Gene3D G3DSA:3.40.250.10 478 567 4.4E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Gene3D G3DSA:3.50.50.60 7 357 1.5E-171 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 SUPERFAMILY SSF51905 4 205 2.9E-46 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Pfam PF00581 Rhodanese-like domain 479 555 1.0E-9 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Gene3D G3DSA:3.50.50.60 123 457 1.5E-171 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 SUPERFAMILY SSF55424 340 463 7.9E-32 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 313 1.7E-61 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 SUPERFAMILY SSF51905 151 326 4.36E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 SMART SM00450 468 563 2.7E-12 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.7E-26 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 3.7E-26 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 3.7E-26 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 3.7E-26 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 3.7E-26 T 13-10-2018 Spica_2495 ecbe465844e8ac514a5259a88e211bca 567 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 448 2.5E-13 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Pfam PF16326 ABC transporter C-terminal domain 559 628 9.9E-16 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 SMART SM00382 28 242 3.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 SMART SM00382 338 510 2.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Pfam PF00005 ABC transporter 329 464 2.8E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Gene3D G3DSA:1.10.287.380 549 632 7.4E-11 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Pfam PF00005 ABC transporter 20 181 2.2E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Pfam PF12848 ABC transporter 220 289 1.1E-6 T 13-10-2018 IPR032781 ABC-transporter extension domain Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 SUPERFAMILY SSF52540 3 240 9.91E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Gene3D G3DSA:3.40.50.300 277 541 2.5E-66 T 13-10-2018 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 Gene3D G3DSA:3.40.50.300 2 275 6.7E-60 T 13-10-2018 Spica_2654 0be4e3a0681c9c175895b33fc7da6221 633 SUPERFAMILY SSF52540 302 517 3.2E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2450 d527a260d1e881d9347f089c01fc2436 282 Pfam PF12833 Helix-turn-helix domain 196 274 2.3E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 Gene3D G3DSA:1.10.10.60 174 223 1.8E-11 T 13-10-2018 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 Pfam PF02311 AraC-like ligand binding domain 22 87 3.1E-12 T 13-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 SUPERFAMILY SSF46689 174 223 4.93E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 Gene3D G3DSA:2.60.120.10 17 95 3.3E-13 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2450 d527a260d1e881d9347f089c01fc2436 282 Gene3D G3DSA:1.10.10.60 224 278 1.1E-15 T 13-10-2018 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 SMART SM00342 190 273 1.8E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 SUPERFAMILY SSF46689 226 276 1.25E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2450 d527a260d1e881d9347f089c01fc2436 282 SUPERFAMILY SSF51215 28 158 1.57E-16 T 13-10-2018 IPR037923 Transcription regulator HTH-like Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 Gene3D G3DSA:3.40.50.720 148 415 2.9E-52 T 13-10-2018 Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 292 320 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 237 8.6E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 379 399 8.6E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 326 343 8.6E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 305 324 8.6E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 167 8.6E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 Pfam PF00106 short chain dehydrogenase 149 337 5.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1986 ac0763f3c2882fc98ad97b80d6c2bc69 417 SUPERFAMILY SSF51735 148 415 1.73E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 SUPERFAMILY SSF53383 2 440 2.57E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 Pfam PF02347 Glycine cleavage system P-protein 3 436 1.1E-114 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 PIRSF PIRSF006815 1 441 1.2E-170 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 Gene3D G3DSA:3.40.640.10 81 343 5.0E-153 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 Gene3D G3DSA:3.90.1150.10 70 437 5.0E-153 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2359 c1a6ed6c39974ed32bdcecdc22a89df3 442 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 440 43.658 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 Spica_2800 2ce5740e835d7638779c34dbbc07d2b8 264 SUPERFAMILY SSF52540 3 231 4.37E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2800 2ce5740e835d7638779c34dbbc07d2b8 264 Pfam PF00005 ABC transporter 22 176 1.2E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2800 2ce5740e835d7638779c34dbbc07d2b8 264 Gene3D G3DSA:3.40.50.300 1 259 3.4E-58 T 13-10-2018 Spica_2800 2ce5740e835d7638779c34dbbc07d2b8 264 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2800 2ce5740e835d7638779c34dbbc07d2b8 264 SMART SM00382 31 225 9.8E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2751 046cb61ec3ec5e99f3c6d91dc3b226e3 248 SUPERFAMILY SSF52540 2 232 6.95E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2751 046cb61ec3ec5e99f3c6d91dc3b226e3 248 SMART SM00382 27 217 8.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2751 046cb61ec3ec5e99f3c6d91dc3b226e3 248 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2751 046cb61ec3ec5e99f3c6d91dc3b226e3 248 Pfam PF00005 ABC transporter 18 167 6.3E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2751 046cb61ec3ec5e99f3c6d91dc3b226e3 248 Gene3D G3DSA:3.40.50.300 1 245 1.0E-68 T 13-10-2018 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 SUPERFAMILY SSF55957 450 579 2.75E-10 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 147 156 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Gene3D G3DSA:3.40.120.10 38 197 3.4E-47 T 13-10-2018 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Gene3D G3DSA:3.40.120.10 332 458 2.8E-33 T 13-10-2018 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 301 316 3.4E-7 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 254 3.4E-7 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 146 160 3.4E-7 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 46 188 1.1E-41 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 508 556 1.3E-7 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Gene3D G3DSA:3.40.120.10 213 331 6.3E-25 T 13-10-2018 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 SUPERFAMILY SSF53738 309 460 3.06E-30 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 SUPERFAMILY SSF53738 224 317 4.18E-16 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 SUPERFAMILY SSF53738 33 242 2.53E-46 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 330 454 6.0E-18 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1029 b8d23b20b8c5dc9133439c7be952f98b 589 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 214 321 2.8E-26 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 SUPERFAMILY SSF53649 17 548 1.03E-50 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 95 317 3.0E-67 T 13-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 Gene3D G3DSA:3.40.720.10 17 545 4.4E-185 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 Pfam PF01676 Metalloenzyme superfamily 17 542 1.1E-66 T 13-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 Gene3D G3DSA:3.40.1450.10 90 333 4.4E-185 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 17 547 1.6E-125 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 PIRSF PIRSF001492 11 555 6.7E-173 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_0862 4df6f67d31d857d4edc222ec62470643 555 SUPERFAMILY SSF64158 90 326 5.23E-68 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Spica_1432 9b7b21d3c5a4c6d0750e47df12379bb6 177 PIRSF PIRSF004553 1 177 1.8E-48 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Spica_1432 9b7b21d3c5a4c6d0750e47df12379bb6 177 SUPERFAMILY SSF53335 1 174 9.7E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1432 9b7b21d3c5a4c6d0750e47df12379bb6 177 Pfam PF03602 Conserved hypothetical protein 95 1 174 8.7E-37 T 13-10-2018 Spica_1432 9b7b21d3c5a4c6d0750e47df12379bb6 177 Gene3D G3DSA:3.40.50.150 1 177 1.4E-43 T 13-10-2018 Spica_1432 9b7b21d3c5a4c6d0750e47df12379bb6 177 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 110 116 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_2496 6556c65b07757b49244c89e4de34c86a 92 Gene3D G3DSA:3.40.250.10 15 90 2.9E-23 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_2496 6556c65b07757b49244c89e4de34c86a 92 SUPERFAMILY SSF52821 13 83 3.8E-24 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Spica_2496 6556c65b07757b49244c89e4de34c86a 92 SMART SM00450 1 86 4.1E-10 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_2496 6556c65b07757b49244c89e4de34c86a 92 Pfam PF00581 Rhodanese-like domain 7 81 2.2E-10 T 13-10-2018 IPR001763 Rhodanese-like domain Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 SUPERFAMILY SSF56801 14 569 1.14E-120 T 13-10-2018 Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 Gene3D G3DSA:3.30.300.30 455 570 2.4E-8 T 13-10-2018 Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 Pfam PF00501 AMP-binding enzyme 31 460 2.0E-99 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 Gene3D G3DSA:3.40.50.12780 314 450 6.6E-42 T 13-10-2018 Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 Gene3D G3DSA:3.40.50.12780 16 305 3.8E-56 T 13-10-2018 Spica_2779 9d5676c3c4871fa3310f15a4c2b4ae73 570 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_2628 9a0a4cc9da570cd6f1586b5eeb7be6fb 434 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 422 3.2E-116 T 13-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Spica_2628 9a0a4cc9da570cd6f1586b5eeb7be6fb 434 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 427 1.7E-130 T 13-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Spica_2628 9a0a4cc9da570cd6f1586b5eeb7be6fb 434 PIRSF PIRSF006066 6 433 2.4E-157 T 13-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 Spica_2181 dcf4d3783780148fb5b0d74e94d739eb 150 Gene3D G3DSA:1.20.1600.10 4 149 3.8E-8 T 13-10-2018 Spica_2181 dcf4d3783780148fb5b0d74e94d739eb 150 SUPERFAMILY SSF56954 31 145 1.22E-8 T 13-10-2018 Spica_1991 423f971d75fd226a9c7f53e7a3bd2912 382 SMART SM00636 92 369 6.4E-8 T 13-10-2018 IPR011583 Chitinase II GO:0008061 Spica_1991 423f971d75fd226a9c7f53e7a3bd2912 382 Gene3D G3DSA:3.20.20.80 113 375 5.4E-56 T 13-10-2018 Spica_1991 423f971d75fd226a9c7f53e7a3bd2912 382 Pfam PF00704 Glycosyl hydrolases family 18 180 368 1.1E-25 T 13-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 Spica_1991 423f971d75fd226a9c7f53e7a3bd2912 382 SUPERFAMILY SSF51445 180 378 3.86E-35 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1991 423f971d75fd226a9c7f53e7a3bd2912 382 Gene3D G3DSA:3.10.50.10 289 340 5.4E-56 T 13-10-2018 IPR029070 Chitinase insertion domain superfamily Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 SMART SM00487 244 442 2.8E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 SUPERFAMILY SSF52540 219 469 4.78E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 SMART SM00490 723 826 4.3E-8 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 Gene3D G3DSA:3.40.50.300 637 849 1.6E-29 T 13-10-2018 Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 Gene3D G3DSA:3.40.50.10810 246 499 5.0E-23 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 Pfam PF00271 Helicase conserved C-terminal domain 702 826 1.1E-13 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 SUPERFAMILY SSF52540 352 879 7.0E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0104 02b6b273915b3b2212ae384d1fb76370 1077 Pfam PF00176 SNF2 family N-terminal domain 260 415 1.4E-11 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spica_0243 5a6a772be95c7feb51dad70c9283e205 345 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 308 18.349 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Spica_0243 5a6a772be95c7feb51dad70c9283e205 345 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 148 160 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Spica_0243 5a6a772be95c7feb51dad70c9283e205 345 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 16 301 7.7E-65 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Spica_0243 5a6a772be95c7feb51dad70c9283e205 345 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 308 1.7E-75 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Spica_2771 b3b1a305d3eecce09f83efbf3a83b2b8 149 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 122 4.0E-13 T 13-10-2018 Spica_0464 061d716706f4451fa56730ec806854f6 293 Gene3D G3DSA:3.90.1150.10 12 44 5.3E-6 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0464 061d716706f4451fa56730ec806854f6 293 SUPERFAMILY SSF53383 12 81 6.68E-7 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0464 061d716706f4451fa56730ec806854f6 293 Gene3D G3DSA:3.40.640.10 45 81 5.3E-6 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0617 a5f6c9a5fe5ba89e64d7ca65ee0fe511 417 Pfam PF00860 Permease family 9 382 6.8E-90 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 Spica_0617 a5f6c9a5fe5ba89e64d7ca65ee0fe511 417 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 330 350 - T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 Spica_0617 a5f6c9a5fe5ba89e64d7ca65ee0fe511 417 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 9 406 1.3E-103 T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 SUPERFAMILY SSF46689 12 80 2.09E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 SUPERFAMILY SSF48498 85 191 4.4E-6 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.8E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.8E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 Gene3D G3DSA:1.10.357.10 8 194 2.1E-24 T 13-10-2018 Spica_2025 e849b3a81af532715cbf24e88fb71ba6 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.2E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0323 f3de385adfc4c6286bbdd5ef6647ea45 478 SUPERFAMILY SSF101960 45 475 1.44E-134 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_0323 f3de385adfc4c6286bbdd5ef6647ea45 478 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 24 469 4.4E-216 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 Spica_0323 f3de385adfc4c6286bbdd5ef6647ea45 478 Pfam PF01458 Uncharacterized protein family (UPF0051) 224 449 7.5E-70 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Spica_2346 fc83481ccf7229c62b8bc019b24dfe7e 133 SUPERFAMILY SSF52172 6 128 1.85E-24 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2346 fc83481ccf7229c62b8bc019b24dfe7e 133 SMART SM00448 5 127 1.1E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2346 fc83481ccf7229c62b8bc019b24dfe7e 133 Gene3D G3DSA:3.40.50.2300 2 132 3.2E-25 T 13-10-2018 Spica_2346 fc83481ccf7229c62b8bc019b24dfe7e 133 Pfam PF00072 Response regulator receiver domain 7 126 2.2E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1037 a55d110da5d3ba7579c5b79646ca8b01 199 Hamap MF_00052_B Ribonuclease HII [rnhB]. 2 190 31.582 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 Spica_1037 a55d110da5d3ba7579c5b79646ca8b01 199 SUPERFAMILY SSF53098 2 189 7.74E-59 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_1037 a55d110da5d3ba7579c5b79646ca8b01 199 Pfam PF01351 Ribonuclease HII 4 187 1.1E-28 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain Spica_1037 a55d110da5d3ba7579c5b79646ca8b01 199 Gene3D G3DSA:3.30.420.10 1 195 6.3E-65 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 9 437 2.9E-187 T 13-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 SUPERFAMILY SSF52540 96 363 3.93E-98 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 7.8E-11 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 Gene3D G3DSA:3.40.50.12240 16 440 4.0E-153 T 13-10-2018 Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 358 3.5E-72 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1667 4d6f443abb61709e2bf34c76c211e904 451 SMART SM00382 161 342 4.5E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 29 549 30.717 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 SUPERFAMILY SSF53244 391 552 4.71E-40 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Pfam PF02875 Mur ligase family, glutamate ligase domain 391 477 1.1E-17 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Gene3D G3DSA:3.40.1390.10 35 130 5.3E-21 T 13-10-2018 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 SUPERFAMILY SSF53623 131 389 6.41E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 SUPERFAMILY SSF63418 43 129 5.23E-21 T 13-10-2018 IPR035911 MurE/MurF, N-terminal Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Gene3D G3DSA:3.90.190.20 395 553 2.6E-52 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Gene3D G3DSA:3.40.1190.10 131 394 2.7E-62 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Pfam PF01225 Mur ligase family, catalytic domain 57 101 5.1E-10 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 53 549 1.1E-153 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Spica_0984 a06dd2ab30440bcb2811f1ecc3889f47 556 Pfam PF08245 Mur ligase middle domain 140 369 2.7E-36 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 33 305 40.825 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 65 92 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 SMART SM00650 49 225 5.7E-48 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 SUPERFAMILY SSF53335 32 306 9.76E-49 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 Gene3D G3DSA:1.10.8.100 227 306 6.6E-15 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 35 302 5.9E-67 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 Pfam PF00398 Ribosomal RNA adenine dimethylase 36 261 1.0E-38 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spica_1586 30f3b7e6c5c3c0b82d206f0e7c5ba684 310 Gene3D G3DSA:3.40.50.150 17 225 6.3E-49 T 13-10-2018 Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 PRINTS PR01270 Histone deacetylase superfamily signature 166 189 7.0E-13 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 PRINTS PR01270 Histone deacetylase superfamily signature 200 215 7.0E-13 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 PRINTS PR01270 Histone deacetylase superfamily signature 289 299 7.0E-13 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 Pfam PF00850 Histone deacetylase domain 53 349 1.2E-30 T 13-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 SUPERFAMILY SSF52768 58 361 3.02E-38 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily Spica_2234 53dff7d1cc486244b5fc8900ad551bef 363 Gene3D G3DSA:3.40.800.20 28 363 9.4E-38 T 13-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 Spica_0619 7a95da3cc8f3ba91cb14e721e9d50ac4 610 Pfam PF01095 Pectinesterase 303 590 4.8E-43 T 13-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 Spica_0619 7a95da3cc8f3ba91cb14e721e9d50ac4 610 SUPERFAMILY SSF51126 303 593 1.18E-55 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_0619 7a95da3cc8f3ba91cb14e721e9d50ac4 610 Gene3D G3DSA:2.160.20.10 297 608 1.0E-69 T 13-10-2018 IPR012334 Pectin lyase fold Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 SMART SM00633 89 357 1.8E-83 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 SUPERFAMILY SSF51445 48 359 4.02E-98 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 PRINTS PR00134 Glycosyl hydrolase family 10 signature 207 218 1.5E-13 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 PRINTS PR00134 Glycosyl hydrolase family 10 signature 120 132 1.5E-13 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 PRINTS PR00134 Glycosyl hydrolase family 10 signature 163 174 1.5E-13 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 PRINTS PR00134 Glycosyl hydrolase family 10 signature 237 249 1.5E-13 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 Gene3D G3DSA:3.20.20.80 44 357 2.3E-101 T 13-10-2018 Spica_0823 d39c4fa48d7ec2fdd13978c8e758da8f 361 Pfam PF00331 Glycosyl hydrolase family 10 53 354 6.6E-94 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Spica_2614 b04ca2dfa5635c2fa5b630d4a45bf856 658 SUPERFAMILY SSF51445 8 649 5.29E-114 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2614 b04ca2dfa5635c2fa5b630d4a45bf856 658 Pfam PF02446 4-alpha-glucanotransferase 15 634 5.4E-135 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 Spica_2614 b04ca2dfa5635c2fa5b630d4a45bf856 658 Gene3D G3DSA:3.20.20.80 455 657 1.3E-42 T 13-10-2018 Spica_2614 b04ca2dfa5635c2fa5b630d4a45bf856 658 Gene3D G3DSA:3.20.20.80 5 335 1.7E-91 T 13-10-2018 Spica_0158 fe727b0512eb5c05cbda94494d5162a6 176 Pfam PF01894 Uncharacterised protein family UPF0047 58 173 4.3E-35 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0158 fe727b0512eb5c05cbda94494d5162a6 176 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 45 176 1.2E-32 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0158 fe727b0512eb5c05cbda94494d5162a6 176 PIRSF PIRSF004681 39 176 7.4E-40 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 Spica_0158 fe727b0512eb5c05cbda94494d5162a6 176 SUPERFAMILY SSF111038 39 176 1.96E-45 T 13-10-2018 IPR035917 YjbQ-like superfamily Spica_0158 fe727b0512eb5c05cbda94494d5162a6 176 Gene3D G3DSA:2.60.120.460 31 176 2.6E-50 T 13-10-2018 IPR035917 YjbQ-like superfamily Spica_0173 a9e44062eb44a433957afbaeab9454c8 253 Gene3D G3DSA:1.10.150.240 17 118 2.8E-24 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_0173 a9e44062eb44a433957afbaeab9454c8 253 Gene3D G3DSA:3.40.50.1000 5 222 2.8E-24 T 13-10-2018 IPR023214 HAD superfamily Spica_0173 a9e44062eb44a433957afbaeab9454c8 253 SUPERFAMILY SSF56784 5 245 1.49E-36 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0173 a9e44062eb44a433957afbaeab9454c8 253 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 138 212 8.9E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_0173 a9e44062eb44a433957afbaeab9454c8 253 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 218 9.2E-20 T 13-10-2018 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 Gene3D G3DSA:3.50.7.10 191 371 2.1E-238 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 PRINTS PR00298 60kDa chaperonin signature 26 52 5.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 PRINTS PR00298 60kDa chaperonin signature 82 109 5.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 PRINTS PR00298 60kDa chaperonin signature 267 290 5.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 PRINTS PR00298 60kDa chaperonin signature 349 374 5.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 PRINTS PR00298 60kDa chaperonin signature 397 418 5.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 Gene3D G3DSA:1.10.560.10 7 522 2.1E-238 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 SUPERFAMILY SSF52029 183 375 3.89E-85 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 528 1.1E-265 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 Gene3D G3DSA:3.30.260.10 135 409 2.1E-238 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 7.3E-103 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Spica_0427 940d6f7db768fade0e644dd4528e0725 546 SUPERFAMILY SSF48592 6 522 4.43E-77 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 SUPERFAMILY SSF54849 136 204 9.84E-25 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Spica_0427 940d6f7db768fade0e644dd4528e0725 546 Hamap MF_00600 60 kDa chaperonin [groL]. 1 542 42.617 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Spica_2565 9f044e6873c62d5b01fbf68921ad721c 770 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 7 171 1.2E-20 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_2565 9f044e6873c62d5b01fbf68921ad721c 770 SMART SM00044 1 155 7.1E-5 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_2565 9f044e6873c62d5b01fbf68921ad721c 770 Pfam PF13239 2TM domain 406 455 8.6E-9 T 13-10-2018 IPR025698 2TM domain Spica_2565 9f044e6873c62d5b01fbf68921ad721c 770 SUPERFAMILY SSF55073 8 177 3.77E-46 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2565 9f044e6873c62d5b01fbf68921ad721c 770 Gene3D G3DSA:3.30.70.1230 7 188 3.6E-48 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2798 ff96a5b8075e1f7934dfc584dcfeda2a 328 SUPERFAMILY SSF46785 14 67 1.32E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2798 ff96a5b8075e1f7934dfc584dcfeda2a 328 Pfam PF08279 HTH domain 14 52 6.9E-6 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_2798 ff96a5b8075e1f7934dfc584dcfeda2a 328 Gene3D G3DSA:1.10.10.10 5 55 7.6E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2798 ff96a5b8075e1f7934dfc584dcfeda2a 328 Pfam PF13280 WYL domain 151 323 8.5E-34 T 13-10-2018 IPR026881 WYL domain Spica_2834 8adb0939ed184f12ec0205692761f388 244 Pfam PF02219 Methylenetetrahydrofolate reductase 55 161 2.8E-7 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Spica_2834 8adb0939ed184f12ec0205692761f388 244 Gene3D G3DSA:3.20.20.220 40 207 9.3E-15 T 13-10-2018 Spica_2834 8adb0939ed184f12ec0205692761f388 244 SUPERFAMILY SSF51730 2 232 1.94E-35 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 SUPERFAMILY SSF52540 273 486 4.99E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 Pfam PF00005 ABC transporter 275 427 4.0E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 Pfam PF00005 ABC transporter 22 169 3.6E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 Gene3D G3DSA:3.40.50.300 1 238 1.3E-56 T 13-10-2018 Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 SMART SM00382 31 217 1.2E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 SMART SM00382 282 484 5.5 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 Gene3D G3DSA:3.40.50.300 261 494 6.3E-38 T 13-10-2018 Spica_2318 d74f26ce36ec18374a830a3f38de8dd1 503 SUPERFAMILY SSF52540 6 227 2.45E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 SUPERFAMILY SSF47336 1 77 7.59E-22 T 13-10-2018 IPR036736 ACP-like superfamily Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 76 3.0E-17 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 Gene3D G3DSA:1.10.1200.10 1 78 1.1E-26 T 13-10-2018 IPR036736 ACP-like superfamily Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 Pfam PF00550 Phosphopantetheine attachment site 7 73 8.7E-15 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 20.329 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Spica_1405 6af6041c85346f9244c1b8598a29fa7d 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 5.6E-31 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Spica_2211 7d952818467aca2b138d9eff5bdf519c 1071 Pfam PF13555 P-loop containing region of AAA domain 4 62 6.4E-19 T 13-10-2018 Spica_2211 7d952818467aca2b138d9eff5bdf519c 1071 Gene3D G3DSA:3.40.50.300 778 1038 1.2E-6 T 13-10-2018 Spica_2211 7d952818467aca2b138d9eff5bdf519c 1071 Gene3D G3DSA:3.40.1140.10 2 205 1.6E-11 T 13-10-2018 Spica_2211 7d952818467aca2b138d9eff5bdf519c 1071 Pfam PF13558 Putative exonuclease SbcCD, C subunit 926 1019 1.7E-21 T 13-10-2018 Spica_2211 7d952818467aca2b138d9eff5bdf519c 1071 SUPERFAMILY SSF52540 16 1028 1.7E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2404 c0a8c34a34fb443f190ba20588f3ad64 411 Pfam PF00375 Sodium:dicarboxylate symporter family 4 395 2.8E-28 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Spica_2404 c0a8c34a34fb443f190ba20588f3ad64 411 Gene3D G3DSA:1.10.3860.10 1 409 2.4E-34 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Spica_2404 c0a8c34a34fb443f190ba20588f3ad64 411 SUPERFAMILY SSF118215 4 396 8.24E-30 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Pfam PF01833 IPT/TIG domain 125 216 3.7E-4 T 13-10-2018 IPR002909 IPT domain Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Pfam PF01833 IPT/TIG domain 27 107 9.9E-7 T 13-10-2018 IPR002909 IPT domain Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 SUPERFAMILY SSF81296 125 219 8.24E-8 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Pfam PF01841 Transglutaminase-like superfamily 358 458 5.6E-14 T 13-10-2018 IPR002931 Transglutaminase-like Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 SMART SM00460 398 460 2.7E-5 T 13-10-2018 IPR002931 Transglutaminase-like Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Gene3D G3DSA:2.60.40.10 124 222 6.0E-14 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Gene3D G3DSA:2.60.40.10 20 107 1.9E-11 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 Gene3D G3DSA:3.10.620.30 309 475 4.8E-13 T 13-10-2018 Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 SUPERFAMILY SSF54001 352 471 7.2E-16 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_0664 b199c7778778ac4c1e2c2ee57df17614 542 SUPERFAMILY SSF81296 26 102 9.33E-10 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 Gene3D G3DSA:3.30.1240.10 88 192 2.3E-70 T 13-10-2018 Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 SUPERFAMILY SSF56784 2 269 1.78E-69 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 2.8E-57 T 13-10-2018 Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 3.8E-24 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 Gene3D G3DSA:3.40.50.1000 5 265 2.3E-70 T 13-10-2018 IPR023214 HAD superfamily Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 13-10-2018 Spica_2784 5c71b7e0cb60c3b112495725efe68fad 276 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 4.9E-54 T 13-10-2018 IPR000150 Cof family GO:0016787 Spica_2646 5f5978a84761dc67e494b6cb429fb9cb 124 SMART SM00345 13 72 3.3E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_2646 5f5978a84761dc67e494b6cb429fb9cb 124 SUPERFAMILY SSF46785 2 76 1.92E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2646 5f5978a84761dc67e494b6cb429fb9cb 124 Gene3D G3DSA:1.10.10.10 6 122 3.9E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2646 5f5978a84761dc67e494b6cb429fb9cb 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 9.4E-14 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 Gene3D G3DSA:2.30.22.10 161 216 2.8E-16 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 Hamap MF_01151 Protein GrpE [grpE]. 23 217 19.11 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 PRINTS PR00773 GrpE protein signature 169 184 4.3E-28 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 PRINTS PR00773 GrpE protein signature 114 129 4.3E-28 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 PRINTS PR00773 GrpE protein signature 196 215 4.3E-28 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 PRINTS PR00773 GrpE protein signature 86 102 4.3E-28 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 Pfam PF01025 GrpE 53 215 1.8E-47 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 SUPERFAMILY SSF58014 65 157 9.55E-26 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 ProSitePatterns PS01071 grpE protein signature. 172 215 - T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 SUPERFAMILY SSF51064 164 216 3.27E-14 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Spica_2741 9790fa65be92b87f6ad43188501f6dcf 242 Gene3D G3DSA:3.90.20.20 41 158 2.0E-31 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Spica_2276 373067bbda2333dc734edad0bba8dc43 158 SUPERFAMILY SSF52218 5 157 6.42E-13 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_2276 373067bbda2333dc734edad0bba8dc43 158 Gene3D G3DSA:3.40.50.360 2 153 5.0E-21 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0255 b8d75d17199d56c5e94a2c56fcbbbf10 212 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 32 56 5.8E-6 T 13-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin Spica_1864 9695689d68b7c7cd7867b980542fdc8d 331 Pfam PF13407 Periplasmic binding protein domain 28 300 9.6E-63 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_1864 9695689d68b7c7cd7867b980542fdc8d 331 SUPERFAMILY SSF53822 24 330 3.37E-80 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1864 9695689d68b7c7cd7867b980542fdc8d 331 Gene3D G3DSA:3.40.50.2300 28 302 3.7E-113 T 13-10-2018 Spica_1864 9695689d68b7c7cd7867b980542fdc8d 331 Gene3D G3DSA:3.40.50.2300 132 280 3.7E-113 T 13-10-2018 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 433 589 1.6E-29 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Gene3D G3DSA:2.40.30.10 602 719 1.0E-38 T 13-10-2018 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Gene3D G3DSA:3.40.50.300 427 601 2.2E-70 T 13-10-2018 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 SUPERFAMILY SSF50447 832 928 2.5E-32 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Gene3D G3DSA:2.40.30.10 832 929 8.1E-32 T 13-10-2018 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Pfam PF00009 Elongation factor Tu GTP binding domain 435 591 7.1E-33 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 SUPERFAMILY SSF52540 413 603 1.99E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 ProSitePatterns PS01176 Initiation factor 2 signature. 881 903 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Gene3D G3DSA:3.40.50.10050 724 831 2.5E-39 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 SUPERFAMILY SSF52156 707 837 1.83E-36 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 10 928 17.168 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 SUPERFAMILY SSF50447 603 686 3.09E-24 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 355 405 1.6E-17 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 Pfam PF11987 Translation-initiation factor 2 716 820 1.3E-36 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 Spica_1354 9f07a5f780ac455e39fc49593d09e498 940 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 348 929 3.1E-264 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Spica_2730 86df757d3c9021b5e4a1e588122c7a20 96 SUPERFAMILY SSF69754 1 96 3.01E-16 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like Spica_2730 86df757d3c9021b5e4a1e588122c7a20 96 Gene3D G3DSA:3.30.160.100 1 95 4.5E-16 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like Spica_2730 86df757d3c9021b5e4a1e588122c7a20 96 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 5.7E-15 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Spica_2730 86df757d3c9021b5e4a1e588122c7a20 96 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 96 3.4E-13 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Gene3D G3DSA:3.40.50.300 73 439 2.4E-162 T 13-10-2018 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Gene3D G3DSA:2.40.30.20 1 71 5.6E-24 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 SUPERFAMILY SSF52540 189 445 5.94E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 209 2.2E-31 T 13-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Gene3D G3DSA:1.10.1140.10 440 592 2.4E-42 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Gene3D G3DSA:2.40.50.100 115 191 2.4E-162 T 13-10-2018 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 218 439 4.2E-89 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 SUPERFAMILY SSF50615 4 71 3.14E-13 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 SUPERFAMILY SSF47917 451 540 2.62E-19 T 13-10-2018 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 590 48.849 T 13-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1816 9f9827ce9e86daf4fa6b9a33615fe719 597 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 4.5E-12 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_0993 9297dc55ffba19500d74063e00838636 140 Gene3D G3DSA:1.20.120.50 2 138 6.9E-38 T 13-10-2018 IPR035938 Hemerythrin-like superfamily Spica_0993 9297dc55ffba19500d74063e00838636 140 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 8 134 4.7E-36 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 Spica_0993 9297dc55ffba19500d74063e00838636 140 SUPERFAMILY SSF47188 4 134 9.81E-33 T 13-10-2018 IPR035938 Hemerythrin-like superfamily Spica_0993 9297dc55ffba19500d74063e00838636 140 ProSitePatterns PS00550 Hemerythrin family signature. 63 86 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 Spica_0993 9297dc55ffba19500d74063e00838636 140 Pfam PF01814 Hemerythrin HHE cation binding domain 17 129 1.6E-10 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 144 160 4.2E-13 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 103 118 4.2E-13 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 54 62 4.2E-13 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 TIGRFAM TIGR00077 lspA: signal peptidase II 5 171 2.3E-32 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 Pfam PF01252 Signal peptidase (SPase) II 13 164 2.2E-27 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 4 169 13.57 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_0022 2a21b94e5b4805eae2d8bf0e3de3cc5a 172 ProSitePatterns PS00855 Signal peptidases II signature. 106 118 - T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 Gene3D G3DSA:3.40.50.2300 298 421 1.0E-28 T 13-10-2018 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 Gene3D G3DSA:3.40.50.12740 2 217 1.4E-22 T 13-10-2018 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 SUPERFAMILY SSF52172 302 419 3.56E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 SMART SM00448 305 416 2.3E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 SMART SM00448 2 115 9.9E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 Pfam PF00072 Response regulator receiver domain 307 415 3.9E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 Pfam PF00072 Response regulator receiver domain 4 114 3.0E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2370 974e56c2a6cb449ff23e023a5943b990 424 SUPERFAMILY SSF52172 1 135 5.69E-24 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0551 25f89feb80a03dd72581879ee3c76e7b 191 Pfam PF02417 Chromate transporter 12 177 6.7E-33 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 Gene3D G3DSA:3.50.30.20 10 167 8.1E-58 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 12 374 7.4E-129 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 Gene3D G3DSA:3.40.50.880 168 376 3.2E-63 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 SUPERFAMILY SSF52021 11 159 1.83E-51 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 SUPERFAMILY SSF52317 190 375 8.88E-54 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 12 153 3.3E-49 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 10 377 40.238 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 SMART SM01097 10 154 7.5E-75 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00097 Anthranilate synthase component II signature 348 361 2.0E-6 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00097 Anthranilate synthase component II signature 263 274 2.0E-6 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00097 Anthranilate synthase component II signature 235 244 2.0E-6 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 Pfam PF00117 Glutamine amidotransferase class-I 198 371 5.4E-45 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 235 244 2.0E-11 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 348 361 2.0E-11 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 263 274 2.0E-11 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 263 279 8.5E-38 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 305 316 8.5E-38 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 280 297 8.5E-38 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 232 246 8.5E-38 T 13-10-2018 Spica_0876 4af76ca9c8f62e9b0d149076feb207ff 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 196 210 8.5E-38 T 13-10-2018 Spica_0031 f8e47d4062d4a3068e1a0cf8c429dd40 317 Pfam PF13407 Periplasmic binding protein domain 47 297 9.2E-27 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0031 f8e47d4062d4a3068e1a0cf8c429dd40 317 SUPERFAMILY SSF53822 44 317 3.08E-31 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0031 f8e47d4062d4a3068e1a0cf8c429dd40 317 Gene3D G3DSA:3.40.50.2300 144 315 5.2E-38 T 13-10-2018 Spica_0031 f8e47d4062d4a3068e1a0cf8c429dd40 317 Gene3D G3DSA:3.40.50.2300 54 308 5.2E-38 T 13-10-2018 Spica_2806 31e39d5293cb5e4d4768ed4d68760b75 448 PIRSF PIRSF006304 4 447 3.0E-109 T 13-10-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 Spica_2806 31e39d5293cb5e4d4768ed4d68760b75 448 Pfam PF03611 PTS system sugar-specific permease component 11 388 3.2E-49 T 13-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SUPERFAMILY SSF54001 400 524 4.07E-34 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00460 444 515 2.8E-17 T 13-10-2018 IPR002931 Transglutaminase-like Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 755 788 2.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 857 890 250.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 823 856 100.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 789 822 410.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 1181 1220 250.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 997 1030 49.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SMART SM00028 891 924 140.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 Gene3D G3DSA:1.25.40.10 748 891 3.2E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 Pfam PF13181 Tetratricopeptide repeat 1001 1021 0.15 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 Gene3D G3DSA:1.25.40.10 892 1062 3.3E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 Pfam PF01841 Transglutaminase-like superfamily 398 513 1.2E-22 T 13-10-2018 IPR002931 Transglutaminase-like Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SUPERFAMILY SSF48452 897 1026 3.13E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 SUPERFAMILY SSF48452 755 920 1.18E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2854 c3742226615db3d8fb722dccd837621d 1320 Gene3D G3DSA:3.10.620.30 366 539 3.5E-22 T 13-10-2018 Spica_0607 6cfbc3a19f44e2e2e2869b1ab6ad0776 181 Pfam PF05685 Putative restriction endonuclease 23 171 3.3E-28 T 13-10-2018 IPR008538 Domain of unknown function DUF820 Spica_0607 6cfbc3a19f44e2e2e2869b1ab6ad0776 181 SUPERFAMILY SSF52980 14 175 4.13E-34 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_0607 6cfbc3a19f44e2e2e2869b1ab6ad0776 181 Gene3D G3DSA:3.90.1570.10 12 177 2.0E-29 T 13-10-2018 Spica_1286 63c8414c032e873ba2d5be8e70601ccd 323 Gene3D G3DSA:3.40.50.300 1 227 5.4E-66 T 13-10-2018 Spica_1286 63c8414c032e873ba2d5be8e70601ccd 323 SMART SM00382 26 210 1.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1286 63c8414c032e873ba2d5be8e70601ccd 323 SUPERFAMILY SSF52540 2 218 2.39E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1286 63c8414c032e873ba2d5be8e70601ccd 323 Pfam PF00005 ABC transporter 18 160 1.0E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0954 a0b2881c1ef433ec363b6dca2ca29cdc 280 SUPERFAMILY SSF53098 110 271 1.77E-47 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0954 a0b2881c1ef433ec363b6dca2ca29cdc 280 Pfam PF00665 Integrase core domain 112 222 2.6E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Spica_0954 a0b2881c1ef433ec363b6dca2ca29cdc 280 Gene3D G3DSA:3.30.420.10 107 266 1.6E-20 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_0954 a0b2881c1ef433ec363b6dca2ca29cdc 280 Pfam PF13276 HTH-like domain 33 89 4.7E-12 T 13-10-2018 IPR025948 HTH-like domain Spica_2183 a0b2881c1ef433ec363b6dca2ca29cdc 280 SUPERFAMILY SSF53098 110 271 1.77E-47 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_2183 a0b2881c1ef433ec363b6dca2ca29cdc 280 Pfam PF00665 Integrase core domain 112 222 2.6E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Spica_2183 a0b2881c1ef433ec363b6dca2ca29cdc 280 Gene3D G3DSA:3.30.420.10 107 266 1.6E-20 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_2183 a0b2881c1ef433ec363b6dca2ca29cdc 280 Pfam PF13276 HTH-like domain 33 89 4.7E-12 T 13-10-2018 IPR025948 HTH-like domain Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 Pfam PF02096 60Kd inner membrane protein 35 215 9.1E-24 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 SUPERFAMILY SSF53649 642 769 3.05E-7 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 Gene3D G3DSA:3.40.720.10 473 821 5.1E-8 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 PRINTS PR00701 60kDa inner membrane protein signature 100 123 5.7E-5 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 PRINTS PR00701 60kDa inner membrane protein signature 185 208 5.7E-5 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Spica_2138 d3df9d80bc10782478a15118fa1c0060 877 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 35 215 1.3E-24 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 PIRSF PIRSF006439 9 569 6.0E-151 T 13-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 29 203 1.0E-14 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 Gene3D G3DSA:3.40.50.970 4 196 1.6E-50 T 13-10-2018 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 SUPERFAMILY SSF52518 16 231 1.37E-54 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 Gene3D G3DSA:3.40.50.970 387 545 8.4E-9 T 13-10-2018 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 491 1.7E-12 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Spica_1261 720a9ff5e1f6a64b810926d33138912f 573 SUPERFAMILY SSF52518 372 553 5.24E-19 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2689 73ef4875e744117f0e01c58ce24f3155 222 Gene3D G3DSA:3.20.19.10 4 187 6.7E-47 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Spica_2689 73ef4875e744117f0e01c58ce24f3155 222 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 10 156 7.4E-35 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Spica_2689 73ef4875e744117f0e01c58ce24f3155 222 SUPERFAMILY SSF52016 8 189 6.28E-42 T 13-10-2018 Spica_2689 73ef4875e744117f0e01c58ce24f3155 222 Pfam PF00694 Aconitase C-terminal domain 18 117 8.5E-18 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Gene3D G3DSA:3.40.50.140 8 146 2.3E-48 T 13-10-2018 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 SMART SM00437 254 518 2.2E-108 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Gene3D G3DSA:3.30.65.10 579 628 4.9E-13 T 13-10-2018 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 15 620 7.6E-248 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Hamap MF_00952 DNA topoisomerase 1 [topA]. 13 650 52.452 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 SMART SM00436 116 204 3.6E-52 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Gene3D G3DSA:1.10.290.10 262 395 2.6E-153 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Pfam PF01131 DNA topoisomerase 140 555 2.9E-127 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 291 313 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 174 192 9.4E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 380 396 9.4E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 87 100 9.4E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 304 313 9.4E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 481 495 9.4E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 667 701 5.6E-6 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 587 621 1.6E-12 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 624 660 1.7E-7 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Gene3D G3DSA:1.10.460.10 147 558 2.6E-153 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 SUPERFAMILY SSF56712 13 597 1.7E-185 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 SMART SM00493 13 113 4.1E-27 T 13-10-2018 IPR006171 TOPRIM domain Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Gene3D G3DSA:2.70.20.10 196 465 2.6E-153 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 SUPERFAMILY SSF57783 582 622 9.35E-13 T 13-10-2018 Spica_1677 f05a7731fe7ae9cb79f0374375ebc150 712 Pfam PF01751 Toprim domain 14 125 5.0E-27 T 13-10-2018 IPR006171 TOPRIM domain Spica_0496 cdd449a76bebaa9921b02a93e71e7804 185 SUPERFAMILY SSF56300 10 173 9.84E-36 T 13-10-2018 Spica_0496 cdd449a76bebaa9921b02a93e71e7804 185 Gene3D G3DSA:3.60.21.10 5 178 1.3E-35 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_0496 cdd449a76bebaa9921b02a93e71e7804 185 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 10 157 5.5E-25 T 13-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Spica_0496 cdd449a76bebaa9921b02a93e71e7804 185 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 10 156 2.4E-21 T 13-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 Spica_2619 17168a22b21836e35af526ddc043e045 275 SUPERFAMILY SSF161098 72 255 3.4E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2619 17168a22b21836e35af526ddc043e045 275 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 68 163 4.5E-27 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Spica_2619 17168a22b21836e35af526ddc043e045 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 269 1.6E-26 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2619 17168a22b21836e35af526ddc043e045 275 Gene3D G3DSA:1.10.3720.10 63 271 4.3E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0209 8fbfe04d5f681a47f5fef66bb9627d80 297 SUPERFAMILY SSF89550 3 283 5.49E-32 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_0209 8fbfe04d5f681a47f5fef66bb9627d80 297 Pfam PF02811 PHP domain 9 232 9.8E-8 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_0209 8fbfe04d5f681a47f5fef66bb9627d80 297 SMART SM00481 7 72 8.3E-11 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_0209 8fbfe04d5f681a47f5fef66bb9627d80 297 Gene3D G3DSA:3.20.20.140 9 278 1.0E-47 T 13-10-2018 Spica_0209 8fbfe04d5f681a47f5fef66bb9627d80 297 Gene3D G3DSA:1.10.150.650 102 187 1.0E-47 T 13-10-2018 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 Pfam PF02609 Exonuclease VII small subunit 6 57 1.8E-14 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 5 60 1.2E-16 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 SUPERFAMILY SSF116842 3 63 1.44E-14 T 13-10-2018 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 PIRSF PIRSF006488 1 76 3.1E-17 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 5 65 12.164 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 Gene3D G3DSA:1.10.287.1040 1 74 1.0E-16 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 Spica_1639 38dc84f95d33ac12de71348d2d953587 79 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 20 46 0.001 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Spica_1208 ea066fac984d9552d23c21b686ee425e 263 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1208 ea066fac984d9552d23c21b686ee425e 263 SUPERFAMILY SSF52540 4 231 7.66E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1208 ea066fac984d9552d23c21b686ee425e 263 SMART SM00382 31 219 3.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1208 ea066fac984d9552d23c21b686ee425e 263 Gene3D G3DSA:3.40.50.300 2 259 6.1E-63 T 13-10-2018 Spica_1208 ea066fac984d9552d23c21b686ee425e 263 Pfam PF00005 ABC transporter 23 170 1.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Gene3D G3DSA:3.40.50.620 26 530 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Pfam PF08264 Anticodon-binding domain of tRNA 609 754 1.1E-37 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Hamap MF_02004 Valine--tRNA ligase [valS]. 6 886 15.496 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 SUPERFAMILY SSF50677 195 347 2.22E-58 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Gene3D G3DSA:3.90.740.10 179 349 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Gene3D G3DSA:1.10.287.380 814 886 3.3E-10 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 825 885 2.9E-9 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 SUPERFAMILY SSF52374 5 574 7.88E-143 T 13-10-2018 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 SUPERFAMILY SSF47323 581 835 5.79E-55 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 352 365 1.4E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 481 499 1.4E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.4E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 1.4E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.4E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 SUPERFAMILY SSF46589 821 885 7.32E-11 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 868 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 568 4.4E-206 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 Gene3D G3DSA:1.10.730.10 6 742 0.0 T 13-10-2018 Spica_1829 4ce1a51e39a9881f8e2968a522548c3d 886 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0448 6f99ce80b37c4f67c31aab92752479f4 325 SUPERFAMILY SSF110997 246 318 4.18E-13 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Spica_0448 6f99ce80b37c4f67c31aab92752479f4 325 Pfam PF05036 Sporulation related domain 245 315 3.5E-16 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Spica_0448 6f99ce80b37c4f67c31aab92752479f4 325 Gene3D G3DSA:3.30.70.1070 239 311 7.1E-11 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Spica_1898 14fef52bac4b8130e44ebbf3864930de 198 SUPERFAMILY SSF55144 4 196 1.74E-29 T 13-10-2018 IPR009097 Cyclic phosphodiesterase Spica_1898 14fef52bac4b8130e44ebbf3864930de 198 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 196 1.1E-27 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Spica_1898 14fef52bac4b8130e44ebbf3864930de 198 Pfam PF02834 LigT like Phosphoesterase 9 66 3.7E-10 T 13-10-2018 IPR014051 Phosphoesterase, HXTX Spica_1898 14fef52bac4b8130e44ebbf3864930de 198 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 196 20.922 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 Spica_1898 14fef52bac4b8130e44ebbf3864930de 198 Gene3D G3DSA:3.90.1140.10 3 197 3.4E-39 T 13-10-2018 Spica_0581 8a8982e0f128fee19f90f0e0af64704b 2238 SUPERFAMILY SSF81296 183 265 2.52E-5 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0581 8a8982e0f128fee19f90f0e0af64704b 2238 Gene3D G3DSA:2.60.40.10 374 462 6.6E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_0581 8a8982e0f128fee19f90f0e0af64704b 2238 Gene3D G3DSA:2.60.40.10 87 179 1.7E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2659 d8ca633176b8d870afd7e24b44c9e518 384 Gene3D G3DSA:3.40.50.2300 63 335 1.7E-108 T 13-10-2018 Spica_2659 d8ca633176b8d870afd7e24b44c9e518 384 SUPERFAMILY SSF53822 60 295 1.04E-8 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2659 d8ca633176b8d870afd7e24b44c9e518 384 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 60 363 9.0E-63 T 13-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 Spica_2659 d8ca633176b8d870afd7e24b44c9e518 384 Gene3D G3DSA:3.40.50.2300 166 372 1.7E-108 T 13-10-2018 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 SMART SM00862 156 229 7.3E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 SUPERFAMILY SSF46894 135 229 7.65E-29 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 SMART SM00448 4 117 4.9E-46 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 Pfam PF00072 Response regulator receiver domain 6 118 2.1E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 Gene3D G3DSA:3.40.50.2300 2 134 1.6E-41 T 13-10-2018 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 SUPERFAMILY SSF52172 3 137 6.97E-44 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 229 3.9E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_0767 d9f6b28b2b8f637c575c7a4f7d8c4cb2 236 Gene3D G3DSA:1.10.10.10 135 235 1.4E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 PRINTS PR00690 Adhesin family signature 203 224 8.5E-6 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 PRINTS PR00690 Adhesin family signature 66 79 8.5E-6 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 PRINTS PR00690 Adhesin family signature 79 96 8.5E-6 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 PRINTS PR00690 Adhesin family signature 254 272 8.5E-6 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 Gene3D G3DSA:3.40.50.1980 37 191 2.3E-34 T 13-10-2018 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 288 5.6E-49 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 SUPERFAMILY SSF53807 35 305 1.22E-68 T 13-10-2018 Spica_2152 d07ae78164fdb16fbe58de14fe6d7a0a 306 Gene3D G3DSA:3.40.50.1980 204 306 2.7E-33 T 13-10-2018 Spica_0971 b30fd06605915085408cb898b08098a3 246 Pfam PF04143 Sulphur transport 71 237 5.6E-30 T 13-10-2018 IPR007272 Sulphur transport domain Spica_0305 73677e536bfb52a446200fbc6f24763e 158 Gene3D G3DSA:3.60.15.10 42 92 5.4E-11 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0305 73677e536bfb52a446200fbc6f24763e 158 Gene3D G3DSA:3.60.15.10 93 158 9.4E-12 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0305 73677e536bfb52a446200fbc6f24763e 158 Pfam PF13483 Beta-lactamase superfamily domain 45 94 1.2E-7 T 13-10-2018 Spica_0305 73677e536bfb52a446200fbc6f24763e 158 SUPERFAMILY SSF56281 45 93 9.1E-7 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0371 ab1f2173235bd630e6145725d1075dda 426 SUPERFAMILY SSF103473 1 412 1.2E-53 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_0371 ab1f2173235bd630e6145725d1075dda 426 Gene3D G3DSA:1.20.1250.20 213 416 2.7E-21 T 13-10-2018 Spica_0371 ab1f2173235bd630e6145725d1075dda 426 Pfam PF07690 Major Facilitator Superfamily 18 348 4.4E-30 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_0371 ab1f2173235bd630e6145725d1075dda 426 Gene3D G3DSA:1.20.1250.20 7 207 2.5E-23 T 13-10-2018 Spica_1148 fb7ed976b52c4772283bae832dd20618 263 Gene3D G3DSA:3.40.50.720 1 160 2.9E-34 T 13-10-2018 Spica_1148 fb7ed976b52c4772283bae832dd20618 263 Pfam PF02153 Prephenate dehydrogenase 44 179 2.4E-20 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Spica_1148 fb7ed976b52c4772283bae832dd20618 263 SUPERFAMILY SSF51735 1 154 2.27E-29 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1148 fb7ed976b52c4772283bae832dd20618 263 SUPERFAMILY SSF48179 155 259 6.63E-8 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_0761 b4fbbf4980dc92aa6dd86f4987cc2ee3 212 SUPERFAMILY SSF55469 11 209 6.54E-43 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_0761 b4fbbf4980dc92aa6dd86f4987cc2ee3 212 Gene3D G3DSA:3.40.109.10 9 209 1.8E-45 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Spica_0761 b4fbbf4980dc92aa6dd86f4987cc2ee3 212 Pfam PF00881 Nitroreductase family 16 191 1.2E-23 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 SUPERFAMILY SSF52540 14 161 2.24E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 Pfam PF01715 IPP transferase 51 303 2.5E-71 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 Gene3D G3DSA:1.10.20.140 125 203 1.7E-89 T 13-10-2018 Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 14 324 27.854 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 14 311 1.7E-81 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Spica_1198 4bb3d952f7d2fc28eb0888d8e568d14a 331 Gene3D G3DSA:3.40.50.300 18 307 1.7E-89 T 13-10-2018 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 Hamap MF_00455 Xylose isomerase [xylA]. 18 444 51.401 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 11 444 7.3E-204 T 13-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 SUPERFAMILY SSF51658 10 446 3.42E-157 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 100 122 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 141 161 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 164 183 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 308 319 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 341 352 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 215 234 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 237 261 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 188 209 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 PRINTS PR00688 Xylose isomerase signature 279 306 3.7E-78 T 13-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 Spica_2745 7ea25dfdf3acaff544990f14ea8e5c44 447 Gene3D G3DSA:3.20.20.150 9 447 1.9E-176 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Gene3D G3DSA:3.40.50.300 317 494 2.0E-67 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Hamap MF_01973 Lon protease [lon]. 16 783 63.526 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 581 780 3.1E-74 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 SUPERFAMILY SSF54211 606 782 4.93E-50 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Gene3D G3DSA:1.10.8.60 495 595 1.8E-26 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PIRSF PIRSF001174 5 785 3.4E-292 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 TIGRFAM TIGR00763 lon: endopeptidase La 17 782 4.0E-275 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 15 205 5.7E-33 T 13-10-2018 IPR003111 Lon, substrate-binding domain Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 359 378 2.0E-48 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 684 703 2.0E-48 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 606 622 2.0E-48 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 714 733 2.0E-48 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 737 755 2.0E-48 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 355 491 1.0E-23 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 687 695 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 SMART SM00464 15 206 1.3E-41 T 13-10-2018 IPR003111 Lon, substrate-binding domain Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 SUPERFAMILY SSF88697 15 205 8.7E-37 T 13-10-2018 IPR015947 PUA-like superfamily Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Gene3D G3DSA:1.20.58.1480 125 248 1.5E-33 T 13-10-2018 Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 SUPERFAMILY SSF52540 314 567 7.2E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Gene3D G3DSA:3.30.230.10 597 783 2.2E-68 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 SMART SM00382 351 496 6.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1109 6cee95af94bc7c87ca9fad76dbb3393a 788 Gene3D G3DSA:2.30.130.40 5 118 1.3E-22 T 13-10-2018 Spica_0180 d9e5a866b019afc6b3ec3919b12ffebf 74 Gene3D G3DSA:3.30.300.130 1 74 1.8E-29 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_0180 d9e5a866b019afc6b3ec3919b12ffebf 74 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 10 74 2.0E-19 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Spica_0180 d9e5a866b019afc6b3ec3919b12ffebf 74 SUPERFAMILY SSF117916 3 74 2.35E-25 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_0180 d9e5a866b019afc6b3ec3919b12ffebf 74 Pfam PF01106 NifU-like domain 6 72 6.9E-28 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 Gene3D G3DSA:4.10.910.10 72 121 4.1E-28 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 SUPERFAMILY SSF46946 2 120 1.26E-46 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 7.6E-54 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.587 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 Gene3D G3DSA:1.10.8.50 1 71 1.2E-29 T 13-10-2018 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 PIRSF PIRSF002134 1 121 7.0E-46 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0407 6ef95d2a955e212655a0222a7ed15d84 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 6.1E-32 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_1438 27c8bbfb392a40811e09333df4ec8f61 134 Pfam PF00293 NUDIX domain 8 127 2.9E-17 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_1438 27c8bbfb392a40811e09333df4ec8f61 134 PRINTS PR00502 NUDIX hydrolase family signature 35 49 2.5E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_1438 27c8bbfb392a40811e09333df4ec8f61 134 PRINTS PR00502 NUDIX hydrolase family signature 49 64 2.5E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_1438 27c8bbfb392a40811e09333df4ec8f61 134 Gene3D G3DSA:3.90.79.10 7 132 8.9E-30 T 13-10-2018 Spica_1438 27c8bbfb392a40811e09333df4ec8f61 134 SUPERFAMILY SSF55811 8 128 4.47E-29 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 SUPERFAMILY SSF54862 3 54 1.63E-18 T 13-10-2018 Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 Pfam PF13187 4Fe-4S dicluster domain 8 53 2.0E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 PRINTS PR00354 7Fe ferredoxin signature 33 50 4.0E-5 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 PRINTS PR00354 7Fe ferredoxin signature 17 27 4.0E-5 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Spica_0858 49e7de851c9d7e0be13c670cc6e3c252 56 Gene3D G3DSA:3.30.70.20 2 55 4.0E-20 T 13-10-2018 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 Gene3D G3DSA:3.30.70.141 179 379 1.8E-38 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 Pfam PF00334 Nucleoside diphosphate kinase 187 240 2.0E-6 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 Pfam PF00334 Nucleoside diphosphate kinase 262 375 3.8E-17 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 SUPERFAMILY SSF54919 5 166 3.01E-12 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 Gene3D G3DSA:3.30.70.141 1 178 5.7E-6 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 SMART SM00562 186 380 5.3E-13 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 358 366 - T 13-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_0834 a11b18b5ba129d316cc428ce4b8296ff 394 SUPERFAMILY SSF54919 186 375 4.19E-32 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_2692 342400f08759360be2d069e7b1ac03e1 441 Pfam PF07690 Major Facilitator Superfamily 33 323 4.9E-39 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_2692 342400f08759360be2d069e7b1ac03e1 441 SUPERFAMILY SSF103473 7 440 1.23E-80 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_2692 342400f08759360be2d069e7b1ac03e1 441 Gene3D G3DSA:1.20.1250.20 17 441 1.1E-89 T 13-10-2018 Spica_1025 757b8d52e497e1dcd22084887a236767 342 Gene3D G3DSA:3.40.50.150 156 339 4.8E-24 T 13-10-2018 Spica_1025 757b8d52e497e1dcd22084887a236767 342 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 260 266 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_1025 757b8d52e497e1dcd22084887a236767 342 SUPERFAMILY SSF53335 135 304 2.71E-18 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1025 757b8d52e497e1dcd22084887a236767 342 Pfam PF01170 Putative RNA methylase family UPF0020 163 316 2.9E-16 T 13-10-2018 IPR000241 Putative RNA methylase domain Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SUPERFAMILY SSF57850 824 858 7.07E-5 T 13-10-2018 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Gene3D G3DSA:1.25.40.10 317 475 4.6E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SUPERFAMILY SSF48452 500 759 5.13E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Gene3D G3DSA:2.60.120.560 46 194 7.4E-14 T 13-10-2018 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Gene3D G3DSA:1.25.40.10 492 629 1.0E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Gene3D G3DSA:1.25.40.10 630 782 5.9E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Pfam PF13181 Tetratricopeptide repeat 347 376 0.0018 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Gene3D G3DSA:1.25.40.10 223 316 4.8E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 699 732 0.02 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 309 342 310.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 632 665 33.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 343 376 0.0011 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 565 598 10.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 494 527 16.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SMART SM00028 272 305 140.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Pfam PF13432 Tetratricopeptide repeat 706 743 0.009 T 13-10-2018 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Pfam PF13432 Tetratricopeptide repeat 571 627 0.0014 T 13-10-2018 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 Pfam PF13432 Tetratricopeptide repeat 638 694 0.0089 T 13-10-2018 Spica_0422 ea7921c142ef73288c72b9c21834ff1a 875 SUPERFAMILY SSF48452 310 457 5.84E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0944 f01fdeac4388721853f87e847a7eb89e 588 Gene3D G3DSA:1.10.287.950 47 241 2.4E-10 T 13-10-2018 Spica_0944 f01fdeac4388721853f87e847a7eb89e 588 SUPERFAMILY SSF58104 69 264 2.22E-10 T 13-10-2018 Spica_2582 247792a854cc264ecd62cc580b44a162 329 Pfam PF06144 DNA polymerase III, delta subunit 7 172 2.7E-13 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 Spica_2582 247792a854cc264ecd62cc580b44a162 329 Gene3D G3DSA:1.20.272.10 196 323 1.5E-18 T 13-10-2018 Spica_2582 247792a854cc264ecd62cc580b44a162 329 SUPERFAMILY SSF52540 6 192 6.38E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2582 247792a854cc264ecd62cc580b44a162 329 Gene3D G3DSA:1.10.8.60 129 195 3.4E-10 T 13-10-2018 Spica_2582 247792a854cc264ecd62cc580b44a162 329 Gene3D G3DSA:3.40.50.300 4 121 1.2E-17 T 13-10-2018 Spica_2582 247792a854cc264ecd62cc580b44a162 329 SUPERFAMILY SSF48019 197 318 2.81E-12 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Spica_2582 247792a854cc264ecd62cc580b44a162 329 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 6 316 2.5E-43 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 650 725 7.2E-19 T 13-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Pfam PF02065 Melibiase 290 635 2.1E-165 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Gene3D G3DSA:3.20.20.70 310 632 1.8E-134 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Gene3D G3DSA:2.60.40.1180 633 729 2.1E-21 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 33 285 1.9E-89 T 13-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 408 430 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 358 373 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 545 561 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 241 256 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 330 344 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 520 536 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 292 312 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 466 481 7.8E-62 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 Gene3D G3DSA:2.70.98.60 1 309 1.3E-119 T 13-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 SUPERFAMILY SSF51445 325 661 1.34E-107 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2220 b2d7f57069ab4734945bf6700a0ee61a 729 PIRSF PIRSF005536 1 729 1.5E-289 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 SUPERFAMILY SSF56276 49 177 9.81E-20 T 13-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 Gene3D G3DSA:3.60.90.10 92 188 8.6E-6 T 13-10-2018 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 265 115.805 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 Pfam PF02675 S-adenosylmethionine decarboxylase 45 173 1.5E-25 T 13-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 9 264 3.8E-109 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Spica_0254 ff69d7b1494d9c4dec2fee38437bf3bf 265 PIRSF PIRSF001356 5 265 9.0E-109 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 Spica_2253 1e1cc197b4d09d6b89c8333eb85c79da 469 Gene3D G3DSA:3.40.50.2300 371 469 2.9E-36 T 13-10-2018 Spica_2253 1e1cc197b4d09d6b89c8333eb85c79da 469 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 17 351 5.2E-165 T 13-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 Spica_2253 1e1cc197b4d09d6b89c8333eb85c79da 469 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 382 463 4.9E-11 T 13-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 Spica_2253 1e1cc197b4d09d6b89c8333eb85c79da 469 Pfam PF02378 Phosphotransferase system, EIIC 26 285 1.9E-20 T 13-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 Spica_2253 1e1cc197b4d09d6b89c8333eb85c79da 469 SUPERFAMILY SSF52794 380 468 6.41E-25 T 13-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 Spica_1564 451832a6930a9927ab9efd2d5b044be9 481 Gene3D G3DSA:3.30.70.1450 388 477 1.6E-18 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_1564 451832a6930a9927ab9efd2d5b044be9 481 Pfam PF00999 Sodium/hydrogen exchanger family 8 378 3.4E-59 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spica_1564 451832a6930a9927ab9efd2d5b044be9 481 Gene3D G3DSA:1.20.1530.20 1 387 2.5E-25 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Spica_1564 451832a6930a9927ab9efd2d5b044be9 481 SUPERFAMILY SSF116726 392 472 4.19E-15 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Spica_1564 451832a6930a9927ab9efd2d5b044be9 481 Pfam PF02080 TrkA-C domain 407 473 2.7E-14 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 SUPERFAMILY SSF53383 105 470 2.64E-84 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 Gene3D G3DSA:1.10.10.10 4 80 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 SMART SM00345 20 79 1.3E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 4.6E-15 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 Gene3D G3DSA:3.40.640.10 144 365 2.3E-99 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 Gene3D G3DSA:3.90.1150.10 105 467 2.3E-99 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 Pfam PF00155 Aminotransferase class I and II 126 463 1.0E-24 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_0930 bbbdcb69881a8ebdecf6f2daf20f4ecf 476 SUPERFAMILY SSF46785 7 83 1.02E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2303 a256443805423e8789cb7825b7fcd3bf 131 Pfam PF01909 Nucleotidyltransferase domain 13 76 3.5E-5 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spica_2303 a256443805423e8789cb7825b7fcd3bf 131 SUPERFAMILY SSF81301 6 109 5.23E-11 T 13-10-2018 Spica_2303 a256443805423e8789cb7825b7fcd3bf 131 Gene3D G3DSA:3.30.460.10 2 94 1.9E-9 T 13-10-2018 Spica_0449 0232efc5326428cf609c648a4db7aa8e 221 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 19 178 9.0E-28 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Spica_0449 0232efc5326428cf609c648a4db7aa8e 221 Pfam PF01121 Dephospho-CoA kinase 19 175 1.4E-23 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Spica_0449 0232efc5326428cf609c648a4db7aa8e 221 Gene3D G3DSA:3.40.50.300 2 217 3.3E-41 T 13-10-2018 Spica_0449 0232efc5326428cf609c648a4db7aa8e 221 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 17 216 17.062 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Spica_0449 0232efc5326428cf609c648a4db7aa8e 221 SUPERFAMILY SSF52540 17 193 5.8E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 Gene3D G3DSA:1.10.287.1080 7 129 1.3E-35 T 13-10-2018 Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 33 106 6.1E-19 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 174 241 1.2E-8 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 SUPERFAMILY SSF101386 11 110 3.93E-20 T 13-10-2018 Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 TIGRFAM TIGR00444 mazG: MazG family protein 17 268 5.4E-87 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 SUPERFAMILY SSF101386 143 247 5.96E-27 T 13-10-2018 Spica_2488 3aaf48256b3301c4f856623d07dc699c 273 Gene3D G3DSA:1.10.287.1080 135 271 2.0E-48 T 13-10-2018 Spica_2639 04027dbf11fb2b7147dd71907240965b 308 Gene3D G3DSA:3.40.718.10 6 303 1.7E-102 T 13-10-2018 Spica_2639 04027dbf11fb2b7147dd71907240965b 308 SUPERFAMILY SSF53659 17 302 4.93E-62 T 13-10-2018 Spica_2639 04027dbf11fb2b7147dd71907240965b 308 Pfam PF01515 Phosphate acetyl/butaryl transferase 82 299 5.0E-47 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_2639 04027dbf11fb2b7147dd71907240965b 308 Pfam PF01515 Phosphate acetyl/butaryl transferase 13 76 3.9E-5 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_2639 04027dbf11fb2b7147dd71907240965b 308 PIRSF PIRSF000428 2 306 3.7E-86 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_0403 8a1ee14926956728fed17acac21a54d0 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.034 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0403 8a1ee14926956728fed17acac21a54d0 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 2.3E-24 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0403 8a1ee14926956728fed17acac21a54d0 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 13-10-2018 IPR018038 Ribosomal protein L30, conserved site Spica_0403 8a1ee14926956728fed17acac21a54d0 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 55 1.2E-18 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Spica_0403 8a1ee14926956728fed17acac21a54d0 61 PIRSF PIRSF002211 1 61 6.0E-28 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0403 8a1ee14926956728fed17acac21a54d0 61 Gene3D G3DSA:3.30.1390.20 1 59 1.2E-24 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Spica_0403 8a1ee14926956728fed17acac21a54d0 61 SUPERFAMILY SSF55129 3 60 4.97E-19 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 Gene3D G3DSA:3.40.630.30 9 284 1.5E-76 T 13-10-2018 Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 SUPERFAMILY SSF55729 134 285 8.79E-47 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 SUPERFAMILY SSF55729 8 133 2.12E-18 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 PIRSF PIRSF018688 3 290 2.1E-75 T 13-10-2018 IPR016732 Uncharacterised conserved protein UCP018688 Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 Gene3D G3DSA:3.40.630.30 121 282 1.5E-76 T 13-10-2018 Spica_2642 34531e05e5b751624ea2f82aaefb02cd 296 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 29 285 5.5E-36 T 13-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Gene3D G3DSA:1.10.287.950 312 433 1.0E-10 T 13-10-2018 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Pfam PF00672 HAMP domain 312 360 4.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Gene3D G3DSA:3.30.450.20 149 291 6.3E-15 T 13-10-2018 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 SMART SM00283 409 656 1.6E-41 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 SUPERFAMILY SSF58104 334 648 2.09E-48 T 13-10-2018 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Pfam PF02743 Cache domain 50 273 1.5E-17 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 478 624 1.3E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 SMART SM00304 312 366 4.2E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2545 0a1cbf935a34f39a1ffed553b45c8175 699 Gene3D G3DSA:1.10.287.950 434 650 8.2E-43 T 13-10-2018 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 Pfam PF01270 Glycosyl hydrolases family 8 47 297 4.1E-24 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 Gene3D G3DSA:1.50.10.10 2 362 2.0E-148 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 PRINTS PR00735 Glycosyl hydrolase family 8 signature 347 361 3.4E-14 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 PRINTS PR00735 Glycosyl hydrolase family 8 signature 116 134 3.4E-14 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 PRINTS PR00735 Glycosyl hydrolase family 8 signature 184 201 3.4E-14 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 PRINTS PR00735 Glycosyl hydrolase family 8 signature 227 238 3.4E-14 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 PRINTS PR00735 Glycosyl hydrolase family 8 signature 57 70 3.4E-14 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_0597 af35bf7044f8a8b15056e739a95b5a2f 367 SUPERFAMILY SSF48208 8 367 8.5E-111 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 SUPERFAMILY SSF52540 76 352 2.48E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 SMART SM00487 26 224 1.3E-54 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 SMART SM00490 260 341 6.4E-32 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Pfam PF00270 DEAD/DEAH box helicase 32 194 1.1E-44 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Pfam PF03880 DbpA RNA binding domain 532 587 3.5E-10 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Gene3D G3DSA:3.30.70.330 532 592 3.6E-5 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Pfam PF00271 Helicase conserved C-terminal domain 248 341 4.4E-26 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Gene3D G3DSA:3.40.50.300 3 213 1.8E-69 T 13-10-2018 Spica_1955 3a35d84aceed6fbaefc1e7eaac89f765 606 Gene3D G3DSA:3.40.50.300 218 412 5.2E-47 T 13-10-2018 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 SMART SM00228 195 277 1.1E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 SMART SM00228 125 194 6.1E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 Gene3D G3DSA:2.30.42.10 220 302 1.3E-11 T 13-10-2018 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 Gene3D G3DSA:2.30.42.10 144 218 8.4E-20 T 13-10-2018 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 Pfam PF02163 Peptidase family M50 9 435 1.0E-59 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 SUPERFAMILY SSF50156 211 279 7.1E-11 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 Pfam PF13180 PDZ domain 125 202 4.1E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 SUPERFAMILY SSF50156 105 202 1.04E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_1421 abeab716620e8e9bd3ace0323e4c7afc 451 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 5 447 1.1E-81 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 Spica_2154 f105eb8112440812f7971e5c9d88c011 289 Pfam PF00950 ABC 3 transport family 13 270 6.0E-62 T 13-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 Spica_2154 f105eb8112440812f7971e5c9d88c011 289 SUPERFAMILY SSF81345 11 269 8.5E-31 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_2154 f105eb8112440812f7971e5c9d88c011 289 Gene3D G3DSA:1.10.3470.10 41 275 2.6E-8 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 Pfam PF00673 ribosomal L5P family C-terminus 88 181 5.0E-38 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 5 183 42.51 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 SUPERFAMILY SSF55282 7 183 9.89E-74 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 Gene3D G3DSA:3.30.1440.10 3 183 5.3E-77 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 Pfam PF00281 Ribosomal protein L5 29 84 3.2E-27 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 ProSitePatterns PS00358 Ribosomal protein L5 signature. 61 77 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0397 2219528b4dfdeb709d0e7193b12b89ed 183 PIRSF PIRSF002161 1 183 6.0E-63 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0229 c64bfc083953dbd20395e87c171f34c7 192 Pfam PF00486 Transcriptional regulatory protein, C terminal 117 191 6.0E-9 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_0229 c64bfc083953dbd20395e87c171f34c7 192 Gene3D G3DSA:1.10.10.10 91 192 9.7E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0229 c64bfc083953dbd20395e87c171f34c7 192 SUPERFAMILY SSF46894 95 191 2.83E-13 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_2717 e409676aeb7646969070d757882375d3 387 Gene3D G3DSA:3.40.50.2000 1 198 1.7E-31 T 13-10-2018 Spica_2717 e409676aeb7646969070d757882375d3 387 Pfam PF13439 Glycosyltransferase Family 4 17 183 8.8E-25 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_2717 e409676aeb7646969070d757882375d3 387 Gene3D G3DSA:3.40.50.2000 199 363 1.9E-42 T 13-10-2018 Spica_2717 e409676aeb7646969070d757882375d3 387 Pfam PF00534 Glycosyl transferases group 1 199 356 3.5E-37 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_2717 e409676aeb7646969070d757882375d3 387 SUPERFAMILY SSF53756 5 382 1.36E-85 T 13-10-2018 Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 Pfam PF12728 Helix-turn-helix domain 7 55 3.3E-19 T 13-10-2018 Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 Gene3D G3DSA:1.10.1660.10 5 54 7.7E-9 T 13-10-2018 Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 SUPERFAMILY SSF46955 6 55 1.5E-10 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 SUPERFAMILY SSF55804 69 214 5.62E-31 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 73 213 1.9E-29 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 Gene3D G3DSA:3.40.930.10 63 217 1.4E-36 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_1045 03a677e342705c07d60a015f3d8c37e3 217 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 52 3.1E-17 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Spica_2536 016afa23c3812026583c3da5ede76a28 328 Pfam PF00005 ABC transporter 27 186 3.5E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2536 016afa23c3812026583c3da5ede76a28 328 SUPERFAMILY SSF52540 6 256 6.23E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2536 016afa23c3812026583c3da5ede76a28 328 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2536 016afa23c3812026583c3da5ede76a28 328 SMART SM00382 35 243 3.2E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2536 016afa23c3812026583c3da5ede76a28 328 Gene3D G3DSA:3.40.50.300 4 328 7.9E-99 T 13-10-2018 Spica_2536 016afa23c3812026583c3da5ede76a28 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 322 1.4E-27 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2536 016afa23c3812026583c3da5ede76a28 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 302 4.5E-20 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2490 65fbbd748c324cb6fb57b96169554040 644 Pfam PF02065 Melibiase 284 400 1.7E-18 T 13-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Spica_2490 65fbbd748c324cb6fb57b96169554040 644 Gene3D G3DSA:3.20.20.70 234 563 3.5E-96 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2490 65fbbd748c324cb6fb57b96169554040 644 SUPERFAMILY SSF51445 237 570 4.21E-53 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 SUPERFAMILY SSF55729 24 162 1.66E-8 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 Gene3D G3DSA:3.40.630.30 24 332 8.2E-67 T 13-10-2018 Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 Pfam PF02388 FemAB family 141 219 2.0E-19 T 13-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 Pfam PF02388 FemAB family 240 342 1.8E-29 T 13-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 SUPERFAMILY SSF55729 155 338 1.01E-36 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_1284 42dabe3663014b39959e4b8fb9e1acb9 367 Gene3D G3DSA:3.40.630.30 148 320 8.2E-67 T 13-10-2018 Spica_2079 f8093fd1fd8d3fa1ce65811c3c12ff82 194 Pfam PF12635 Protein of unknown function (DUF3780) 6 175 9.7E-48 T 13-10-2018 IPR024220 Protein of unknown function DUF3780 Spica_2691 77952adef230caf450fbad2d69f269ef 166 Pfam PF10369 Small subunit of acetolactate synthase 90 162 4.8E-25 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2691 77952adef230caf450fbad2d69f269ef 166 SUPERFAMILY SSF55021 7 81 6.72E-19 T 13-10-2018 Spica_2691 77952adef230caf450fbad2d69f269ef 166 Gene3D G3DSA:3.30.70.260 4 84 3.5E-30 T 13-10-2018 Spica_2691 77952adef230caf450fbad2d69f269ef 166 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 7 163 2.9E-49 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Spica_2691 77952adef230caf450fbad2d69f269ef 166 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 8 80 8.0E-17 T 13-10-2018 Spica_2691 77952adef230caf450fbad2d69f269ef 166 Pfam PF13710 ACT domain 17 78 3.3E-15 T 13-10-2018 Spica_2691 77952adef230caf450fbad2d69f269ef 166 SUPERFAMILY SSF55021 84 164 5.83E-22 T 13-10-2018 Spica_2691 77952adef230caf450fbad2d69f269ef 166 Gene3D G3DSA:3.30.70.1150 88 166 4.7E-27 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Spica_2156 17185a84aa47e8b0f9cbea4df76a3d4a 438 Pfam PF01986 Domain of unknown function DUF123 325 412 5.1E-23 T 13-10-2018 IPR002837 Protein of unknown function DUF123 Spica_2156 17185a84aa47e8b0f9cbea4df76a3d4a 438 Pfam PF03749 Sugar fermentation stimulation protein 32 276 1.5E-45 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein Spica_2156 17185a84aa47e8b0f9cbea4df76a3d4a 438 Gene3D G3DSA:2.40.50.580 24 139 4.6E-12 T 13-10-2018 Spica_2156 17185a84aa47e8b0f9cbea4df76a3d4a 438 Gene3D G3DSA:3.40.1350.60 141 290 9.2E-40 T 13-10-2018 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Pfam PF16360 GTP-binding GTPase Middle Region 120 199 5.7E-27 T 13-10-2018 IPR032305 GTP-binding protein, middle domain Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Pfam PF13167 GTP-binding GTPase N-terminal 34 118 2.2E-22 T 13-10-2018 IPR025121 GTPase HflX, N-terminal Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Pfam PF01926 50S ribosome-binding GTPase 207 325 7.1E-20 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 PIRSF PIRSF006809 5 421 7.1E-139 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Gene3D G3DSA:3.40.50.300 204 371 1.4E-42 T 13-10-2018 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 SUPERFAMILY SSF52540 205 364 4.02E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 207 227 1.3E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 1.3E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Hamap MF_00900 GTPase HflX [hflX]. 33 394 45.715 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 14 364 1.1E-127 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Spica_0340 a049198f040ceb6be7172b7ffac2bce7 423 Gene3D G3DSA:3.40.50.11060 23 145 6.5E-33 T 13-10-2018 Spica_0006 1788e3d3f81de456e7e87b910a9ac23e 81 Gene3D G3DSA:3.30.230.10 1 76 3.0E-16 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0006 1788e3d3f81de456e7e87b910a9ac23e 81 SUPERFAMILY SSF54211 3 79 1.87E-15 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0006 1788e3d3f81de456e7e87b910a9ac23e 81 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 1 62 8.0E-7 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Spica_0006 1788e3d3f81de456e7e87b910a9ac23e 81 Pfam PF00825 Ribonuclease P 8 74 3.7E-14 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Spica_0006 1788e3d3f81de456e7e87b910a9ac23e 81 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 74 7.3E-12 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Spica_1884 3dc74585948d9282bbb9def24ddec90f 709 Pfam PF00999 Sodium/hydrogen exchanger family 41 435 2.3E-49 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Spica_1884 3dc74585948d9282bbb9def24ddec90f 709 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 567 707 1.2E-34 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_1884 3dc74585948d9282bbb9def24ddec90f 709 SUPERFAMILY SSF55804 564 708 9.55E-34 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_1884 3dc74585948d9282bbb9def24ddec90f 709 Gene3D G3DSA:3.40.930.10 562 709 2.4E-40 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_1884 3dc74585948d9282bbb9def24ddec90f 709 Gene3D G3DSA:1.20.1530.20 32 442 1.7E-84 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Spica_1648 6de14b01dc718b9eebb140fa1cc6665f 439 ProSitePatterns PS01219 Ammonium transporters signature. 178 203 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Spica_1648 6de14b01dc718b9eebb140fa1cc6665f 439 TIGRFAM TIGR00836 amt: ammonium transporter 33 430 1.8E-132 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Spica_1648 6de14b01dc718b9eebb140fa1cc6665f 439 SUPERFAMILY SSF111352 31 411 1.18E-116 T 13-10-2018 Spica_1648 6de14b01dc718b9eebb140fa1cc6665f 439 Pfam PF00909 Ammonium Transporter Family 36 430 2.6E-126 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Spica_1648 6de14b01dc718b9eebb140fa1cc6665f 439 Gene3D G3DSA:1.10.3430.10 15 437 2.1E-147 T 13-10-2018 IPR029020 Ammonium/urea transporter Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 SUPERFAMILY SSF53649 30 494 4.58E-107 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 PRINTS PR00113 Alkaline phosphatase signature 101 116 7.8E-30 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 PRINTS PR00113 Alkaline phosphatase signature 45 65 7.8E-30 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 PRINTS PR00113 Alkaline phosphatase signature 258 287 7.8E-30 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 PRINTS PR00113 Alkaline phosphatase signature 139 159 7.8E-30 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 ProSitePatterns PS00123 Alkaline phosphatase active site. 101 109 - T 13-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 Pfam PF00245 Alkaline phosphatase 46 492 4.3E-71 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_0723 ef40af8b44964f22f1ae3c3e7a66cf8d 499 SMART SM00098 46 495 1.3E-50 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 118 750 1.4E-141 T 13-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 SUPERFAMILY SSF51998 194 914 4.27E-125 T 13-10-2018 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 31 144 1.3E-37 T 13-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Gene3D G3DSA:3.20.70.20 91 351 4.3E-56 T 13-10-2018 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Gene3D G3DSA:3.20.70.20 776 924 1.3E-29 T 13-10-2018 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Gene3D G3DSA:3.20.70.20 379 775 1.9E-91 T 13-10-2018 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Pfam PF02867 Ribonucleotide reductase, barrel domain 806 910 1.7E-18 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 PRINTS PR01183 Ribonucleotide reductase large chain signature 540 562 1.1E-5 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 PRINTS PR01183 Ribonucleotide reductase large chain signature 272 291 1.1E-5 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_1974 0e58e0c1a9cbb208732b573409ee58d7 1235 Pfam PF02867 Ribonucleotide reductase, barrel domain 195 746 3.0E-106 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Spica_2785 7958c7e65cfe523a24322c92c2800bbe 117 Pfam PF07085 DRTGG domain 5 104 1.8E-6 T 13-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Spica_2785 7958c7e65cfe523a24322c92c2800bbe 117 SUPERFAMILY SSF75138 1 112 3.14E-17 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2785 7958c7e65cfe523a24322c92c2800bbe 117 Gene3D G3DSA:3.40.1390.20 5 103 3.9E-6 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_0498 44875ce832e811205b6b59ce55c62c58 374 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 186 373 1.6E-27 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 SUPERFAMILY SSF81606 168 371 1.7E-9 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 SUPERFAMILY SSF52172 6 133 7.4E-37 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0498 44875ce832e811205b6b59ce55c62c58 374 Gene3D G3DSA:3.40.50.2300 2 134 7.8E-35 T 13-10-2018 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 Pfam PF00072 Response regulator receiver domain 7 119 3.5E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 SMART SM00448 5 118 3.3E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 SMART SM00331 156 374 2.7E-17 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0498 44875ce832e811205b6b59ce55c62c58 374 Gene3D G3DSA:3.60.40.10 135 373 1.3E-38 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2188 d8115d8da71550d245748b456f548bd9 217 Gene3D G3DSA:3.80.10.10 13 197 4.8E-13 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Spica_2188 d8115d8da71550d245748b456f548bd9 217 SUPERFAMILY SSF52058 58 199 1.36E-10 T 13-10-2018 Spica_2412 4a09ffd4a7ee50deba2521e0ae6ee48d 598 Gene3D G3DSA:1.10.287.950 340 554 1.3E-37 T 13-10-2018 Spica_2412 4a09ffd4a7ee50deba2521e0ae6ee48d 598 SUPERFAMILY SSF58104 232 566 1.05E-45 T 13-10-2018 Spica_2412 4a09ffd4a7ee50deba2521e0ae6ee48d 598 Gene3D G3DSA:1.20.1480.50 173 270 2.0E-7 T 13-10-2018 Spica_2412 4a09ffd4a7ee50deba2521e0ae6ee48d 598 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 375 534 1.6E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2412 4a09ffd4a7ee50deba2521e0ae6ee48d 598 SMART SM00283 307 547 6.8E-18 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 21 168 3.3E-48 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 19 172 40.437 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 21 172 1.1E-35 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 SUPERFAMILY SSF53098 20 174 2.31E-43 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 101 117 2.1E-32 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 157 169 2.1E-32 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 125 144 2.1E-32 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 22 35 2.1E-32 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 79 95 2.1E-32 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Spica_1340 25a3b75a901766f1b5020ac5ac9b541c 179 Gene3D G3DSA:3.30.420.10 20 174 1.5E-47 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_0965 e260d56f55ed05f10850e4c36a782655 437 Gene3D G3DSA:3.40.50.150 12 210 9.0E-16 T 13-10-2018 Spica_0965 e260d56f55ed05f10850e4c36a782655 437 Pfam PF05175 Methyltransferase small domain 27 180 9.0E-13 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Spica_0965 e260d56f55ed05f10850e4c36a782655 437 SUPERFAMILY SSF53335 19 207 2.64E-13 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 Pfam PF03102 NeuB family 31 259 1.8E-60 T 13-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 Gene3D G3DSA:3.20.20.70 9 265 1.9E-82 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 SMART SM00858 352 413 0.0018 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 SUPERFAMILY SSF51569 10 259 5.13E-62 T 13-10-2018 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 Pfam PF08666 SAF domain 353 413 6.1E-8 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 Gene3D G3DSA:3.90.1210.10 353 413 4.5E-16 T 13-10-2018 Spica_1337 39eb3ceb2be27321c3c325488c4f5930 413 SUPERFAMILY SSF51269 347 413 8.16E-10 T 13-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 Gene3D G3DSA:3.40.50.970 1 191 8.5E-84 T 13-10-2018 Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 Pfam PF02780 Transketolase, C-terminal domain 193 315 8.6E-34 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 SUPERFAMILY SSF52518 2 203 4.52E-69 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 SUPERFAMILY SSF52922 187 323 7.07E-36 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 Gene3D G3DSA:3.40.50.920 192 324 1.1E-42 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 2.6E-45 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1709 f002950bd06bda2f9a2debd9e4068348 326 SMART SM00861 4 179 2.3E-58 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 Gene3D G3DSA:3.40.50.300 8 190 2.2E-41 T 13-10-2018 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 Pfam PF01202 Shikimate kinase 18 186 1.0E-29 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 SUPERFAMILY SSF52540 7 186 9.0E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 Hamap MF_00109 Shikimate kinase [aroK]. 7 187 21.055 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 PRINTS PR01100 Shikimate kinase family signature 34 47 1.4E-10 T 13-10-2018 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 PRINTS PR01100 Shikimate kinase family signature 110 127 1.4E-10 T 13-10-2018 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 PRINTS PR01100 Shikimate kinase family signature 61 69 1.4E-10 T 13-10-2018 Spica_2063 2b614cb5a85ab043867434d1e54e315b 191 PRINTS PR01100 Shikimate kinase family signature 10 25 1.4E-10 T 13-10-2018 Spica_1940 bf37cff1cd5c095e97879aabd9eba393 296 Pfam PF12706 Beta-lactamase superfamily domain 47 260 1.2E-32 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1940 bf37cff1cd5c095e97879aabd9eba393 296 SUPERFAMILY SSF56281 1 295 1.7E-44 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1940 bf37cff1cd5c095e97879aabd9eba393 296 SMART SM00849 34 260 2.3E-6 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0246 83ef6c467d602644bf99615a57feceaf 673 SUPERFAMILY SSF159941 505 662 1.83E-31 T 13-10-2018 IPR024047 MM3350-like superfamily Spica_0246 83ef6c467d602644bf99615a57feceaf 673 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 503 658 3.3E-33 T 13-10-2018 IPR012912 Plasmid pRiA4b, Orf3 Spica_0246 83ef6c467d602644bf99615a57feceaf 673 Gene3D G3DSA:3.10.290.30 498 662 1.5E-32 T 13-10-2018 IPR024047 MM3350-like superfamily Spica_0430 aebbe22b1bdec3788a5d3d879e240153 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.1E-17 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Spica_0430 aebbe22b1bdec3788a5d3d879e240153 332 SUPERFAMILY SSF55347 129 295 6.54E-35 T 13-10-2018 Spica_0430 aebbe22b1bdec3788a5d3d879e240153 332 SUPERFAMILY SSF51735 3 156 1.27E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0430 aebbe22b1bdec3788a5d3d879e240153 332 Gene3D G3DSA:3.40.50.720 1 122 7.9E-32 T 13-10-2018 Spica_0430 aebbe22b1bdec3788a5d3d879e240153 332 Gene3D G3DSA:3.30.360.10 123 329 3.4E-50 T 13-10-2018 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Gene3D G3DSA:3.20.20.70 1 231 1.7E-60 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 353 421 5.5E-13 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Gene3D G3DSA:1.10.287.1080 337 423 1.2E-19 T 13-10-2018 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Gene3D G3DSA:3.10.20.400 232 325 3.2E-30 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 342 417 2.3E-19 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 261 334 2.8E-29 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 284 333 2.0E-13 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 Pfam PF00977 Histidine biosynthesis protein 1 226 5.3E-45 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 SUPERFAMILY SSF51366 1 231 2.59E-40 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 SUPERFAMILY SSF101386 342 421 1.72E-15 T 13-10-2018 Spica_2436 1e39b86357bd8ff762be23ad7335801b 423 SUPERFAMILY SSF141734 241 344 2.22E-38 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 PIRSF PIRSF015601 1 263 2.1E-55 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 SUPERFAMILY SSF75217 86 259 2.88E-40 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 Gene3D G3DSA:3.40.1280.10 5 267 6.8E-68 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 Pfam PF04452 RNA methyltransferase 18 257 5.5E-55 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 SUPERFAMILY SSF88697 1 67 4.8E-8 T 13-10-2018 IPR015947 PUA-like superfamily Spica_0238 82ec6c2535497a906e0a0f7cbea3dcb3 271 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 260 7.1E-46 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0655 769659f26d9e46102da45851915953d2 108 PIRSF PIRSF003203 2 107 2.1E-29 T 13-10-2018 IPR008407 Branched-chain amino acid transport, AzlD Spica_0655 769659f26d9e46102da45851915953d2 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 102 1.0E-22 T 13-10-2018 IPR008407 Branched-chain amino acid transport, AzlD Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.2090.10 715 802 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.2E-33 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82693 42 134 2.09E-25 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.70.1430 40 810 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Pfam PF00873 AcrB/AcrD/AcrF family 4 1021 1.0E-246 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82866 799 1025 3.53E-51 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82714 716 802 5.75E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82693 570 659 1.1E-8 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.2090.10 177 267 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.70.1320 134 324 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:1.20.1640.10 512 1018 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.70.1440 665 861 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:3.30.70.1430 566 664 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82714 183 265 3.01E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 Gene3D G3DSA:1.20.1640.10 10 511 0.0 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82693 136 322 3.66E-22 T 13-10-2018 Spica_0730 18ad35629906eef7e081d2439b02ddb2 1035 SUPERFAMILY SSF82866 288 488 1.07E-40 T 13-10-2018 Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 328 1.4E-26 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 SUPERFAMILY SSF52540 6 261 4.02E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 Gene3D G3DSA:3.40.50.300 4 333 9.7E-99 T 13-10-2018 Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 Pfam PF00005 ABC transporter 34 189 2.8E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 SMART SM00382 42 239 8.6E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2535 a8a5fc9bed104826895c8a735229ed20 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 308 5.2E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 Pfam PF01266 FAD dependent oxidoreductase 5 338 4.4E-55 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 SUPERFAMILY SSF54373 221 310 4.32E-6 T 13-10-2018 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 1.4E-15 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 304 310 1.4E-15 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 1.4E-15 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 1.4E-15 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 355 1.4E-15 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 Gene3D G3DSA:3.30.9.10 81 311 2.3E-66 T 13-10-2018 Spica_0337 2bf920850499116b57b6ff5436777aa3 392 SUPERFAMILY SSF51905 4 376 2.39E-41 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0337 2bf920850499116b57b6ff5436777aa3 392 Gene3D G3DSA:3.50.50.60 5 361 2.3E-66 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1863 552d585a4ae14d3ae3974c5c8e6cfc93 346 SUPERFAMILY SSF53822 35 327 5.57E-49 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1863 552d585a4ae14d3ae3974c5c8e6cfc93 346 Gene3D G3DSA:3.40.50.2300 139 326 2.8E-79 T 13-10-2018 Spica_1863 552d585a4ae14d3ae3974c5c8e6cfc93 346 Gene3D G3DSA:3.40.50.2300 39 314 2.8E-79 T 13-10-2018 Spica_1863 552d585a4ae14d3ae3974c5c8e6cfc93 346 Pfam PF13407 Periplasmic binding protein domain 38 294 6.2E-42 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2844 f4a2ec89357c430bcab5469aa3f3dc27 444 Pfam PF02386 Cation transport protein 39 422 9.8E-61 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Spica_2078 97857aed7e5301486bba97b918205c11 1024 Pfam PF04465 Protein of unknown function (DUF499) 117 366 2.5E-24 T 13-10-2018 IPR007555 Protein of unknown function DUF499 Spica_2078 97857aed7e5301486bba97b918205c11 1024 Pfam PF13287 Fn3 associated 846 896 8.0E-8 T 13-10-2018 IPR026876 Fn3 associated repeat Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 458 9.9E-85 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 Gene3D G3DSA:3.30.930.10 108 463 4.2E-114 T 13-10-2018 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 Gene3D G3DSA:2.40.50.140 3 107 2.4E-19 T 13-10-2018 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 13 465 1.9E-192 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 465 45.563 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 2.7E-9 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 SUPERFAMILY SSF50249 12 104 1.37E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 223 236 4.5E-15 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 219 4.5E-15 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 380 396 4.5E-15 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 420 434 4.5E-15 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_1628 5b2e23f3c843ed91db880fc1b3523d13 465 SUPERFAMILY SSF55681 97 463 2.59E-99 T 13-10-2018 Spica_0910 3dd2a743746303b47025ea701e6972d8 406 Pfam PF14319 Transposase zinc-binding domain 28 120 7.7E-24 T 13-10-2018 IPR026889 Transposase zinc-binding domain Spica_0910 3dd2a743746303b47025ea701e6972d8 406 Pfam PF04986 Putative transposase 152 315 1.3E-16 T 13-10-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 Spica_2031 d0998b39c0a8297fe32f36bf85ef3376 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 341 3.4E-32 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2031 d0998b39c0a8297fe32f36bf85ef3376 346 SUPERFAMILY SSF161098 115 324 2.75E-14 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2031 d0998b39c0a8297fe32f36bf85ef3376 346 Gene3D G3DSA:1.10.3720.10 108 334 2.1E-17 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 Pfam PF00120 Glutamine synthetase, catalytic domain 188 375 7.8E-23 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 Gene3D G3DSA:3.30.590.10 185 401 1.7E-32 T 13-10-2018 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 Pfam PF12437 Glutamine synthetase type III N terminal 14 175 1.9E-74 T 13-10-2018 IPR022147 Glutamine synthetase type III N-terminal GO:0004356 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 SMART SM01230 176 462 1.3E-44 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 SUPERFAMILY SSF55931 166 584 8.73E-72 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 321 336 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Spica_1646 431f76ef24d921bc99112a5c66e261d2 707 Gene3D G3DSA:1.20.120.1560 565 706 4.5E-40 T 13-10-2018 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 697 861 3.1E-29 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 SMART SM00839 690 954 4.3E-30 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 410 527 5.2E-28 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 463 476 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 SUPERFAMILY SSF51735 684 952 1.36E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 Gene3D G3DSA:3.40.50.10860 405 539 7.3E-31 T 13-10-2018 Spica_0027 0323b5adedd930b88509708d6d0f5b8b 994 SUPERFAMILY SSF53223 409 543 2.3E-29 T 13-10-2018 Spica_2537 0d7a3a7a1931b9a31f7efca37f124a1d 358 Gene3D G3DSA:1.10.3720.10 141 355 1.9E-23 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2537 0d7a3a7a1931b9a31f7efca37f124a1d 358 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 169 353 7.3E-32 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2537 0d7a3a7a1931b9a31f7efca37f124a1d 358 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 66 4.3E-13 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spica_2537 0d7a3a7a1931b9a31f7efca37f124a1d 358 SUPERFAMILY SSF161098 147 336 3.66E-26 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1714 dcf01af41031bbf222365a607ee16853 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 332 3.5E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1714 dcf01af41031bbf222365a607ee16853 341 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 32 330 1.4E-90 T 13-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Spica_1714 dcf01af41031bbf222365a607ee16853 341 Gene3D G3DSA:1.10.3720.10 90 333 5.2E-30 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1714 dcf01af41031bbf222365a607ee16853 341 SUPERFAMILY SSF161098 43 324 2.43E-30 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1371 ece1a5d08fd432c047649100db66e3b3 149 Gene3D G3DSA:3.50.80.10 1 148 2.2E-57 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Spica_1371 ece1a5d08fd432c047649100db66e3b3 149 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 8.9E-57 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Spica_1371 ece1a5d08fd432c047649100db66e3b3 149 SUPERFAMILY SSF69500 1 145 2.09E-56 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Spica_1371 ece1a5d08fd432c047649100db66e3b3 149 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.55 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Spica_1371 ece1a5d08fd432c047649100db66e3b3 149 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.4E-58 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 Gene3D G3DSA:3.60.120.10 5 470 5.1E-137 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 Pfam PF04715 Anthranilate synthase component I, N terminal region 19 154 2.9E-17 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 PRINTS PR00095 Anthranilate synthase component I signature 415 429 2.2E-20 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 PRINTS PR00095 Anthranilate synthase component I signature 320 333 2.2E-20 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 PRINTS PR00095 Anthranilate synthase component I signature 400 414 2.2E-20 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 PRINTS PR00095 Anthranilate synthase component I signature 306 319 2.2E-20 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 SUPERFAMILY SSF56322 24 466 2.35E-131 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Spica_0174 94189d0fb3f2a909270ab077a81591f5 471 Pfam PF00425 chorismate binding enzyme 205 458 1.3E-90 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Gene3D G3DSA:3.30.420.40 399 541 1.9E-76 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 72 247 1.9E-19 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 299 558 1.7E-33 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 297 557 6.3E-41 T 13-10-2018 IPR008275 CoA enzyme activase Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Gene3D G3DSA:3.30.420.40 4 247 1.8E-44 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Gene3D G3DSA:3.30.420.40 88 232 1.8E-44 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Gene3D G3DSA:3.30.420.40 299 558 1.9E-76 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 SUPERFAMILY SSF53067 297 558 4.52E-31 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 SUPERFAMILY SSF53067 1 249 8.29E-16 T 13-10-2018 Spica_0555 be3ebca7237df0352c6d99ddeab4a419 1478 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 659 871 2.2E-50 T 13-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 Spica_0611 d9e3921550096a39a23d44b95746377f 276 Gene3D G3DSA:3.50.30.50 10 138 2.0E-12 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Spica_0611 d9e3921550096a39a23d44b95746377f 276 Pfam PF04199 Putative cyclase 16 117 9.5E-15 T 13-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Spica_0611 d9e3921550096a39a23d44b95746377f 276 Pfam PF02803 Thiolase, C-terminal domain 188 270 1.6E-7 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Spica_0611 d9e3921550096a39a23d44b95746377f 276 SUPERFAMILY SSF102198 13 121 6.02E-15 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 Spica_0611 d9e3921550096a39a23d44b95746377f 276 SUPERFAMILY SSF53901 187 272 2.62E-20 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_0611 d9e3921550096a39a23d44b95746377f 276 Gene3D G3DSA:3.40.47.10 186 276 1.1E-31 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 Pfam PF00206 Lyase 35 305 1.4E-36 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00145 Argininosuccinate lyase family signature 288 304 3.1E-6 T 13-10-2018 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 3.1E-6 T 13-10-2018 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00145 Argininosuccinate lyase family signature 243 267 3.1E-6 T 13-10-2018 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 Gene3D G3DSA:1.20.200.10 111 376 6.5E-72 T 13-10-2018 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 SMART SM00998 389 479 0.0011 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 ProSitePatterns PS00163 Fumarate lyases signature. 288 297 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 SUPERFAMILY SSF48557 27 438 1.24E-66 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 Gene3D G3DSA:1.10.275.10 11 110 9.9E-10 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 2.5E-15 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 2.5E-15 T 13-10-2018 IPR000362 Fumarate lyase family Spica_1850 2213ca95e4e97d890b8f9fb396417e49 488 PRINTS PR00149 Fumarate lyase superfamily signature 288 304 2.5E-15 T 13-10-2018 IPR000362 Fumarate lyase family Spica_2407 79abb0c3203c068785ff214ba4b1705d 215 Gene3D G3DSA:3.40.630.30 15 215 4.7E-49 T 13-10-2018 Spica_2407 79abb0c3203c068785ff214ba4b1705d 215 SUPERFAMILY SSF55729 16 204 1.61E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2407 79abb0c3203c068785ff214ba4b1705d 215 Pfam PF00583 Acetyltransferase (GNAT) family 74 199 5.6E-8 T 13-10-2018 IPR000182 GNAT domain Spica_0219 780046d6c86558065bff1c3b52900f8e 409 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 32 245 2.4E-15 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0219 780046d6c86558065bff1c3b52900f8e 409 Gene3D G3DSA:3.60.40.10 2 254 2.7E-29 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0219 780046d6c86558065bff1c3b52900f8e 409 SMART SM00331 4 245 8.1E-4 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0219 780046d6c86558065bff1c3b52900f8e 409 SUPERFAMILY SSF81606 7 246 3.92E-9 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2833 81c8667e7870ec261b820b526ff587be 266 Gene3D G3DSA:3.10.129.10 1 245 1.7E-57 T 13-10-2018 Spica_2833 81c8667e7870ec261b820b526ff587be 266 SUPERFAMILY SSF54637 2 124 3.09E-34 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_2833 81c8667e7870ec261b820b526ff587be 266 SUPERFAMILY SSF54637 158 220 9.96E-15 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_2833 81c8667e7870ec261b820b526ff587be 266 Pfam PF01643 Acyl-ACP thioesterase 5 218 5.6E-43 T 13-10-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 Gene3D G3DSA:1.20.1480.50 162 261 3.3E-12 T 13-10-2018 Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 SMART SM00387 378 492 1.0E-6 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 SUPERFAMILY SSF158472 204 253 3.66E-7 T 13-10-2018 Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 Pfam PF00672 HAMP domain 204 250 3.9E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 Pfam PF06580 Histidine kinase 284 361 1.6E-22 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 490 2.9E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 SUPERFAMILY SSF55874 338 489 8.51E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1861 bed1b7d904274cbfe21a9a2290bb83ff 494 Gene3D G3DSA:3.30.565.10 357 494 1.6E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0539 738d0a8ced3a1699b588d76eeee58774 1058 Pfam PF04465 Protein of unknown function (DUF499) 249 841 6.2E-35 T 13-10-2018 IPR007555 Protein of unknown function DUF499 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 SUPERFAMILY SSF53738 33 197 3.06E-20 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 Gene3D G3DSA:3.40.120.10 47 206 3.3E-21 T 13-10-2018 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 Gene3D G3DSA:3.40.120.10 358 463 2.6E-11 T 13-10-2018 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 Gene3D G3DSA:3.40.120.10 279 480 2.6E-11 T 13-10-2018 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 72 193 1.3E-20 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_1039 82d69f75d02ad630262ef9ab6241864c 647 SUPERFAMILY SSF55957 604 644 2.88E-5 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Spica_2151 d7c57efe14c6391ed396dacfbc55a70e 320 SUPERFAMILY SSF53822 35 319 1.62E-70 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2151 d7c57efe14c6391ed396dacfbc55a70e 320 Gene3D G3DSA:3.40.50.2300 138 272 4.6E-93 T 13-10-2018 Spica_2151 d7c57efe14c6391ed396dacfbc55a70e 320 Gene3D G3DSA:3.40.50.2300 35 318 4.6E-93 T 13-10-2018 Spica_2151 d7c57efe14c6391ed396dacfbc55a70e 320 Pfam PF13407 Periplasmic binding protein domain 36 291 1.6E-55 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_1819 b4cbb4b0e0a50e8d38b0fa6a91eb1e1e 107 Pfam PF00137 ATP synthase subunit C 45 104 1.9E-13 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Spica_1819 b4cbb4b0e0a50e8d38b0fa6a91eb1e1e 107 SUPERFAMILY SSF81333 39 105 5.1E-14 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Spica_1819 b4cbb4b0e0a50e8d38b0fa6a91eb1e1e 107 Gene3D G3DSA:1.20.120.610 1 106 1.4E-11 T 13-10-2018 Spica_0311 657c8ec42433a66322964c5361b1c5d4 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 284 1.1E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0311 657c8ec42433a66322964c5361b1c5d4 294 SUPERFAMILY SSF161098 54 282 3.53E-55 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0311 657c8ec42433a66322964c5361b1c5d4 294 Gene3D G3DSA:1.10.3720.10 49 292 2.9E-65 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2668 c7829c5eb06b517d81759b9b1a586483 235 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 70 84 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2668 c7829c5eb06b517d81759b9b1a586483 235 Pfam PF00849 RNA pseudouridylate synthase 28 178 9.3E-30 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2668 c7829c5eb06b517d81759b9b1a586483 235 SUPERFAMILY SSF55120 13 227 6.24E-60 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2668 c7829c5eb06b517d81759b9b1a586483 235 Gene3D G3DSA:3.30.2350.10 20 231 7.4E-61 T 13-10-2018 Spica_2361 bb313fcd6ea255a4cb5190f0a74cd6af 49 SUPERFAMILY SSF88723 1 44 4.49E-6 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2361 bb313fcd6ea255a4cb5190f0a74cd6af 49 Gene3D G3DSA:3.40.50.1010 2 47 5.9E-5 T 13-10-2018 Spica_0679 a109c957155e8322cbd7dff6d3952e8e 237 TIGRFAM TIGR00608 radc: DNA repair protein RadC 26 230 5.8E-52 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 Spica_0679 a109c957155e8322cbd7dff6d3952e8e 237 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 182 187 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site Spica_0679 a109c957155e8322cbd7dff6d3952e8e 237 Pfam PF04002 RadC-like JAB domain 113 230 4.3E-39 T 13-10-2018 IPR025657 RadC-like JAB domain Spica_0679 a109c957155e8322cbd7dff6d3952e8e 237 Gene3D G3DSA:3.40.140.10 110 232 2.9E-39 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 407 591 3.0E-48 T 13-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 Pfam PF13625 Helicase conserved C-terminal domain 8 102 6.9E-33 T 13-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 SMART SM00490 478 555 4.4E-10 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 SMART SM00487 226 403 7.6E-18 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 SUPERFAMILY SSF52540 249 566 1.07E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 Gene3D G3DSA:3.40.50.300 408 599 3.8E-46 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 Pfam PF04851 Type III restriction enzyme, res subunit 228 381 2.4E-12 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 Gene3D G3DSA:3.40.50.300 221 407 3.3E-34 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 448 463 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 346 366 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 511 529 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 530 555 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 411 433 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 244 266 6.6E-35 T 13-10-2018 Spica_2543 7c705cf20fce6870aeda99c7a36d2dda 600 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 92 111 6.6E-35 T 13-10-2018 Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 Pfam PF00005 ABC transporter 301 438 5.5E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 SUPERFAMILY SSF52540 3 221 2.51E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 SMART SM00382 30 307 7.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 SMART SM00382 310 487 9.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 Gene3D G3DSA:3.40.50.300 1 230 1.3E-58 T 13-10-2018 Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 Gene3D G3DSA:3.40.50.300 289 492 6.0E-50 T 13-10-2018 Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 SUPERFAMILY SSF52540 297 490 9.15E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0692 44d0bb3a3cce03f1bb2618c4621d4dff 493 Pfam PF00005 ABC transporter 21 160 2.2E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 PIRSF PIRSF000447 1 426 8.1E-162 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 382 4.5E-35 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 Gene3D G3DSA:3.40.47.10 270 414 1.3E-50 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 Gene3D G3DSA:3.40.47.10 1 268 2.1E-89 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 260 5.5E-54 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 SUPERFAMILY SSF53901 228 425 4.72E-68 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 423 7.3E-174 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 SUPERFAMILY SSF53901 2 265 1.33E-73 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Spica_2038 740ccc49c94e3ea0f4679f266d6ebc26 426 SMART SM00825 Beta-ketoacyl synthase 5 426 6.3E-13 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spica_2176 f59b68eedcc9600c2bf9b358bfc465bc 299 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 5 298 2.0E-20 T 13-10-2018 IPR010106 Recombination-promoting nuclease RpnA Spica_2176 f59b68eedcc9600c2bf9b358bfc465bc 299 Pfam PF04754 Putative transposase, YhgA-like 5 200 1.8E-31 T 13-10-2018 IPR006842 Transposase (putative), YhgA-like Spica_2512 7d800d388a2c696542d6980fdf018d79 265 Gene3D G3DSA:3.20.20.190 7 258 1.2E-59 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Spica_2512 7d800d388a2c696542d6980fdf018d79 265 SUPERFAMILY SSF51695 11 253 4.97E-60 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Spica_2512 7d800d388a2c696542d6980fdf018d79 265 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 18 250 9.7E-34 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 Pfam PF00106 short chain dehydrogenase 7 217 6.2E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 167 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.2E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 165 1.3E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 1.3E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 Gene3D G3DSA:3.40.50.720 2 281 3.7E-75 T 13-10-2018 Spica_0605 0da2749a85bf0430e7630e2281f8ddf7 281 SUPERFAMILY SSF51735 5 277 2.03E-68 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2270 f9f2e1db9aa63894296e3e1e1f04d0b1 561 TIGRFAM TIGR00815 sulP: sulfate permease 24 550 5.4E-116 T 13-10-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Spica_2270 f9f2e1db9aa63894296e3e1e1f04d0b1 561 Pfam PF01740 STAS domain 453 544 1.7E-14 T 13-10-2018 IPR002645 STAS domain Spica_2270 f9f2e1db9aa63894296e3e1e1f04d0b1 561 SUPERFAMILY SSF52091 454 559 6.28E-19 T 13-10-2018 IPR036513 STAS domain superfamily Spica_2270 f9f2e1db9aa63894296e3e1e1f04d0b1 561 Gene3D G3DSA:3.30.750.24 439 561 9.8E-27 T 13-10-2018 IPR036513 STAS domain superfamily Spica_2270 f9f2e1db9aa63894296e3e1e1f04d0b1 561 Pfam PF00916 Sulfate permease family 30 393 2.9E-88 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 Spica_2366 ecf2d36060cd0e34a2355ded870fe4e8 422 Gene3D G3DSA:3.90.550.10 10 417 3.0E-99 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2366 ecf2d36060cd0e34a2355ded870fe4e8 422 SUPERFAMILY SSF159283 353 414 1.44E-7 T 13-10-2018 Spica_2366 ecf2d36060cd0e34a2355ded870fe4e8 422 Pfam PF00483 Nucleotidyl transferase 133 336 1.2E-26 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_2366 ecf2d36060cd0e34a2355ded870fe4e8 422 Pfam PF00483 Nucleotidyl transferase 12 115 5.3E-14 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Spica_2366 ecf2d36060cd0e34a2355ded870fe4e8 422 SUPERFAMILY SSF53448 10 332 1.69E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2756 30b04ee10184f3ea7969b4f965e3d17d 261 Pfam PF02405 Permease MlaE 47 257 5.7E-53 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 Spica_0545 126c4175c583b3a903422b064f9d99bb 227 Gene3D G3DSA:3.60.15.10 4 227 8.3E-61 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0545 126c4175c583b3a903422b064f9d99bb 227 Pfam PF00753 Metallo-beta-lactamase superfamily 12 211 9.1E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0545 126c4175c583b3a903422b064f9d99bb 227 SMART SM00849 15 211 2.8E-32 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_0545 126c4175c583b3a903422b064f9d99bb 227 SUPERFAMILY SSF56281 11 223 1.05E-46 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0081 832fbb57da6bba6bbe7f11f3da0b819b 320 Gene3D G3DSA:2.30.30.40 58 114 1.8E-5 T 13-10-2018 Spica_0081 832fbb57da6bba6bbe7f11f3da0b819b 320 Pfam PF08239 Bacterial SH3 domain 267 317 5.3E-8 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type Spica_0081 832fbb57da6bba6bbe7f11f3da0b819b 320 Gene3D G3DSA:2.30.30.40 247 319 1.1E-6 T 13-10-2018 Spica_2251 84a50a2c2405262b0c62474227b2c9fb 147 Gene3D G3DSA:3.40.930.10 3 143 1.7E-41 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2251 84a50a2c2405262b0c62474227b2c9fb 147 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_2251 84a50a2c2405262b0c62474227b2c9fb 147 SUPERFAMILY SSF55804 5 141 1.16E-36 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2251 84a50a2c2405262b0c62474227b2c9fb 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 142 1.7E-31 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 55 1.0E-12 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 Gene3D G3DSA:1.20.5.1150 16 66 1.1E-11 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 18.064 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 Pfam PF01165 Ribosomal protein S21 3 56 1.4E-18 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.8E-10 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.8E-10 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.8E-10 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.8E-10 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1968 6408e88e1256fea51c1d8e3aace23df8 67 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 59 1.3E-20 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_2726 6b3a6a83325cdef75d9576eff4cab6ca 287 SUPERFAMILY SSF109604 8 277 1.26E-67 T 13-10-2018 Spica_2726 6b3a6a83325cdef75d9576eff4cab6ca 287 TIGRFAM TIGR00277 HDIG: HDIG domain 111 213 2.5E-8 T 13-10-2018 IPR006675 HDIG domain Spica_2726 6b3a6a83325cdef75d9576eff4cab6ca 287 Pfam PF08668 HDOD domain 16 213 1.0E-56 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD Spica_2726 6b3a6a83325cdef75d9576eff4cab6ca 287 Gene3D G3DSA:1.10.3210.10 1 283 1.1E-77 T 13-10-2018 Spica_2651 0d6e7e9c8f4219ceea7d73c3bbf45cea 754 Gene3D G3DSA:2.160.10.10 216 409 1.1E-7 T 13-10-2018 Spica_2651 0d6e7e9c8f4219ceea7d73c3bbf45cea 754 SUPERFAMILY SSF51161 271 369 2.02E-6 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_2651 0d6e7e9c8f4219ceea7d73c3bbf45cea 754 Pfam PF16314 Domain of unknown function (DUF4954) 46 750 2.2E-139 T 13-10-2018 IPR032533 Protein of unknown function DUF4954 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Gene3D G3DSA:3.40.50.620 37 584 2.3E-279 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 SUPERFAMILY SSF50677 228 423 1.26E-54 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Gene3D G3DSA:2.30.210.10 585 599 2.3E-279 T 13-10-2018 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Pfam PF08264 Anticodon-binding domain of tRNA 667 774 1.7E-15 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 818 23.174 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Gene3D G3DSA:3.10.20.590 758 818 3.5E-21 T 13-10-2018 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 425 615 1.7E-21 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Gene3D G3DSA:3.90.740.10 230 423 2.3E-279 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 SUPERFAMILY SSF47323 632 819 1.63E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Pfam PF09334 tRNA synthetases class I (M) 43 187 5.7E-19 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Gene3D G3DSA:1.10.730.10 612 754 2.3E-43 T 13-10-2018 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 223 412 4.5E-69 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 SUPERFAMILY SSF52374 3 635 1.73E-147 T 13-10-2018 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 130 147 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 570 580 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 188 201 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 537 559 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 217 236 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 156 172 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 PRINTS PR00985 Leucyl-tRNA synthetase signature 498 516 6.4E-56 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2714 ae13ebd31d276dc998d2289382e664b5 819 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 819 0.0 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 PIRSF PIRSF000774 2 453 1.8E-131 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 10 50 7.2E-14 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Gene3D G3DSA:1.10.10.1330 104 211 1.0E-11 T 13-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Pfam PF04963 Sigma-54 factor, core binding domain 98 279 6.7E-45 T 13-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Gene3D G3DSA:1.10.260.40 342 372 1.9E-5 T 13-10-2018 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Pfam PF04552 Sigma-54, DNA binding domain 296 452 4.8E-55 T 13-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 452 2.4E-122 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 Gene3D G3DSA:1.10.10.60 397 453 6.1E-17 T 13-10-2018 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 434 441 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 PRINTS PR00045 Sigma-54 factor signature 429 447 1.5E-17 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 PRINTS PR00045 Sigma-54 factor signature 355 367 1.5E-17 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 PRINTS PR00045 Sigma-54 factor signature 371 382 1.5E-17 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2731 706a8839ef3c3ab6d345276d825447f4 453 PRINTS PR00045 Sigma-54 factor signature 168 185 1.5E-17 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 80 115 6.9E-12 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 PRINTS PR00618 DksA/TraR zinc finger signature 85 96 5.1E-5 T 13-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 PRINTS PR00618 DksA/TraR zinc finger signature 97 109 5.1E-5 T 13-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 SUPERFAMILY SSF109635 1 80 3.66E-9 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 SUPERFAMILY SSF57716 82 117 3.14E-10 T 13-10-2018 Spica_2373 71b87a070462d8c8964cfaba970c1f11 118 Gene3D G3DSA:1.20.120.910 1 118 3.0E-31 T 13-10-2018 Spica_0234 2a368d4883a924f4bb515284f47ed848 250 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 5 237 6.4E-59 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Spica_0234 2a368d4883a924f4bb515284f47ed848 250 Gene3D G3DSA:3.40.1280.10 1 165 3.7E-52 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0234 2a368d4883a924f4bb515284f47ed848 250 SUPERFAMILY SSF75217 4 165 8.5E-31 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0234 2a368d4883a924f4bb515284f47ed848 250 Gene3D G3DSA:1.10.8.590 172 248 6.3E-7 T 13-10-2018 Spica_0234 2a368d4883a924f4bb515284f47ed848 250 Pfam PF00588 SpoU rRNA Methylase family 6 155 8.7E-33 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spica_0234 2a368d4883a924f4bb515284f47ed848 250 PIRSF PIRSF004808 2 242 8.4E-64 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Spica_1720 c91b769800839a83d9cb54061e74f27a 497 Gene3D G3DSA:3.50.50.60 200 331 3.5E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1720 c91b769800839a83d9cb54061e74f27a 497 Gene3D G3DSA:3.50.50.60 1 94 1.3E-23 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1720 c91b769800839a83d9cb54061e74f27a 497 SUPERFAMILY SSF51905 1 493 5.4E-63 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1720 c91b769800839a83d9cb54061e74f27a 497 Pfam PF01593 Flavin containing amine oxidoreductase 12 477 6.7E-30 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Spica_1720 c91b769800839a83d9cb54061e74f27a 497 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 491 1.1E-138 T 13-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 Spica_1720 c91b769800839a83d9cb54061e74f27a 497 PRINTS PR00419 Adrenodoxin reductase family signature 27 40 2.1E-5 T 13-10-2018 Spica_1720 c91b769800839a83d9cb54061e74f27a 497 PRINTS PR00419 Adrenodoxin reductase family signature 4 26 2.1E-5 T 13-10-2018 Spica_0452 123d2ab7770d260e6e8f79439eecd23c 148 TIGRFAM TIGR00208 fliS: flagellar protein FliS 2 130 6.7E-25 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Spica_0452 123d2ab7770d260e6e8f79439eecd23c 148 Gene3D G3DSA:1.20.120.340 1 133 1.7E-42 T 13-10-2018 Spica_0452 123d2ab7770d260e6e8f79439eecd23c 148 PIRSF PIRSF039090 2 139 4.5E-29 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Spica_0452 123d2ab7770d260e6e8f79439eecd23c 148 SUPERFAMILY SSF101116 5 131 3.79E-33 T 13-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 Spica_0452 123d2ab7770d260e6e8f79439eecd23c 148 Pfam PF02561 Flagellar protein FliS 8 128 7.9E-39 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 SUPERFAMILY SSF57863 83 243 1.39E-17 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 Hamap MF_00201 DNA repair protein RecO [recO]. 3 252 15.241 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 SUPERFAMILY SSF50249 2 76 8.91E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 Pfam PF02565 Recombination protein O C terminal 84 247 2.0E-11 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 TIGRFAM TIGR00613 reco: DNA repair protein RecO 8 245 2.5E-15 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Spica_1972 451fb4e0744a230db35d9daf6e8a6ebe 252 Pfam PF11967 Recombination protein O N terminal 6 73 8.8E-8 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 Gene3D G3DSA:3.30.70.660 109 246 1.3E-34 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 4 247 30.923 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 SUPERFAMILY SSF55120 4 247 3.6E-74 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 242 2.6E-52 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 Gene3D G3DSA:3.30.70.580 2 108 1.9E-34 T 13-10-2018 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 PIRSF PIRSF001430 3 250 2.4E-71 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 Pfam PF01416 tRNA pseudouridine synthase 147 247 1.8E-17 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1205 c358e1e14a6a89a61cb3a0fb3d5f8d14 250 Pfam PF01416 tRNA pseudouridine synthase 10 107 2.6E-9 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 Gene3D G3DSA:3.40.50.150 9 310 1.7E-93 T 13-10-2018 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 9 314 35.679 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 Gene3D G3DSA:1.10.150.170 115 220 1.7E-93 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 PIRSF PIRSF004486 3 315 1.1E-106 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 6 313 1.5E-104 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 SUPERFAMILY SSF81799 117 218 7.59E-31 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 Pfam PF01795 MraW methylase family 7 313 3.3E-115 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Spica_1688 c8b7ba2946c05873b31f76ac020ec343 319 SUPERFAMILY SSF53335 9 314 2.95E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2120 2ee18dfa830172ce3d42d912a2080a3f 285 Gene3D G3DSA:1.10.3720.10 2 273 1.3E-42 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2120 2ee18dfa830172ce3d42d912a2080a3f 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 279 1.0E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2120 2ee18dfa830172ce3d42d912a2080a3f 285 SUPERFAMILY SSF161098 3 285 7.2E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0526 0e7440d6dbde1a56dab06ef88d9fb793 375 SUPERFAMILY SSF53756 3 373 5.1E-112 T 13-10-2018 Spica_0526 0e7440d6dbde1a56dab06ef88d9fb793 375 Gene3D G3DSA:3.40.50.2000 188 327 8.2E-108 T 13-10-2018 Spica_0526 0e7440d6dbde1a56dab06ef88d9fb793 375 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 361 3.0E-93 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_0526 0e7440d6dbde1a56dab06ef88d9fb793 375 Gene3D G3DSA:3.40.50.2000 6 187 8.2E-108 T 13-10-2018 Spica_0526 0e7440d6dbde1a56dab06ef88d9fb793 375 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 362 4.1E-72 T 13-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 Spica_0275 dc04744369c25422999a97b6bad4f686 410 Gene3D G3DSA:3.40.50.2020 219 374 2.8E-78 T 13-10-2018 Spica_0275 dc04744369c25422999a97b6bad4f686 410 SMART SM01400 9 191 1.6E-17 T 13-10-2018 Spica_0275 dc04744369c25422999a97b6bad4f686 410 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 80 398 1.3E-101 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Spica_0275 dc04744369c25422999a97b6bad4f686 410 Gene3D G3DSA:3.40.50.2020 87 386 2.8E-78 T 13-10-2018 Spica_0275 dc04744369c25422999a97b6bad4f686 410 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 87 191 8.0E-28 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Spica_0275 dc04744369c25422999a97b6bad4f686 410 SUPERFAMILY SSF53271 142 360 1.34E-32 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_0275 dc04744369c25422999a97b6bad4f686 410 Pfam PF00156 Phosphoribosyl transferase domain 216 330 2.4E-22 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 SUPERFAMILY SSF52540 6 169 9.45E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 56 71 3.8E-7 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 3.8E-7 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 29 47 3.8E-7 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 Gene3D G3DSA:3.40.50.300 5 200 4.1E-46 T 13-10-2018 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 Pfam PF07664 Ferrous iron transport protein B C terminus 460 512 2.3E-19 T 13-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 12 677 3.8E-188 T 13-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 Pfam PF07670 Nucleoside recognition 518 680 1.9E-29 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 Pfam PF07670 Nucleoside recognition 356 448 8.8E-12 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Spica_0359 36161a3e32ea1ddc2ba1363497b6b261 712 Pfam PF02421 Ferrous iron transport protein B 7 161 5.7E-64 T 13-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 Spica_1634 d71654481f57ee7c11675ec5b9044b5b 644 Gene3D G3DSA:3.40.50.150 425 603 1.3E-33 T 13-10-2018 Spica_1634 d71654481f57ee7c11675ec5b9044b5b 644 Pfam PF13489 Methyltransferase domain 452 595 8.7E-20 T 13-10-2018 Spica_1634 d71654481f57ee7c11675ec5b9044b5b 644 SUPERFAMILY SSF53335 448 608 6.54E-31 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1634 d71654481f57ee7c11675ec5b9044b5b 644 Gene3D G3DSA:3.40.50.2000 157 284 3.6E-14 T 13-10-2018 Spica_0861 711b1865d1079aa6aa91902780c928db 683 SMART SM00283 364 597 1.5E-63 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0861 711b1865d1079aa6aa91902780c928db 683 Gene3D G3DSA:3.30.450.20 144 282 5.6E-24 T 13-10-2018 Spica_0861 711b1865d1079aa6aa91902780c928db 683 Gene3D G3DSA:1.10.287.950 302 599 2.0E-65 T 13-10-2018 Spica_0861 711b1865d1079aa6aa91902780c928db 683 Pfam PF02743 Cache domain 42 264 1.9E-25 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_0861 711b1865d1079aa6aa91902780c928db 683 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 424 584 9.8E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0861 711b1865d1079aa6aa91902780c928db 683 SUPERFAMILY SSF58104 333 598 2.18E-59 T 13-10-2018 Spica_2128 e7ece14e6ee6e58f9f2cd4af99f6a5fd 427 Gene3D G3DSA:1.10.287.950 4 305 1.0E-22 T 13-10-2018 Spica_2128 e7ece14e6ee6e58f9f2cd4af99f6a5fd 427 SUPERFAMILY SSF58104 21 285 2.49E-26 T 13-10-2018 Spica_2128 e7ece14e6ee6e58f9f2cd4af99f6a5fd 427 Gene3D G3DSA:3.30.450.20 309 414 1.5E-12 T 13-10-2018 Spica_2128 e7ece14e6ee6e58f9f2cd4af99f6a5fd 427 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 91 255 4.4E-15 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2128 e7ece14e6ee6e58f9f2cd4af99f6a5fd 427 SUPERFAMILY SSF103190 293 421 5.1E-19 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Gene3D G3DSA:1.20.1480.50 268 362 1.1E-6 T 13-10-2018 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Pfam PF02743 Cache domain 40 265 4.9E-27 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 480 603 1.7E-22 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Gene3D G3DSA:3.30.450.20 135 267 1.2E-22 T 13-10-2018 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 SMART SM00283 399 646 4.5E-42 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 SMART SM00304 302 356 1.2E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Gene3D G3DSA:1.10.287.950 368 646 2.5E-44 T 13-10-2018 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 Pfam PF00672 HAMP domain 302 352 8.7E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_2006 019070e0354b4660dc67a5e3b4596cc9 697 SUPERFAMILY SSF58104 324 647 1.05E-45 T 13-10-2018 Spica_1485 7c08c7e3bd9c8e376dd0bfaac81e5663 115 SUPERFAMILY SSF57662 4 99 8.24E-27 T 13-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 Spica_1485 7c08c7e3bd9c8e376dd0bfaac81e5663 115 Pfam PF02943 Ferredoxin thioredoxin reductase catalytic beta chain 6 96 4.5E-23 T 13-10-2018 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 Spica_1485 7c08c7e3bd9c8e376dd0bfaac81e5663 115 Gene3D G3DSA:3.90.460.10 1 113 1.2E-20 T 13-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 Spica_1059 9b989609e0b7d3db59d17025a26c3a1e 238 Pfam PF14559 Tetratricopeptide repeat 97 158 7.0E-9 T 13-10-2018 Spica_1059 9b989609e0b7d3db59d17025a26c3a1e 238 Gene3D G3DSA:1.25.40.10 36 227 1.3E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1059 9b989609e0b7d3db59d17025a26c3a1e 238 SMART SM00028 83 116 0.42 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1059 9b989609e0b7d3db59d17025a26c3a1e 238 SMART SM00028 182 215 35.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1059 9b989609e0b7d3db59d17025a26c3a1e 238 SUPERFAMILY SSF48452 56 216 2.78E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1535 420e18525fd463afd89e284bc87ac02e 260 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 185 202 - T 13-10-2018 IPR000540 Flagellar motor protein MotA, conserved site Spica_1535 420e18525fd463afd89e284bc87ac02e 260 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 216 9.2E-25 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 PIRSF PIRSF006816 1 256 8.9E-68 T 13-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 Gene3D G3DSA:3.40.50.80 100 204 5.3E-38 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 250 2.7E-13 T 13-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 SUPERFAMILY SSF63380 3 93 6.54E-17 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 Gene3D G3DSA:2.40.30.10 1 92 1.9E-22 T 13-10-2018 Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 Pfam PF00175 Oxidoreductase NAD-binding domain 105 198 2.8E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spica_0134 2d84c0e754eaf123e8d3583b7a933232 287 SUPERFAMILY SSF52343 89 249 1.2E-34 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 109 120 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Gene3D G3DSA:3.30.470.20 131 361 4.8E-77 T 13-10-2018 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 PIRSF PIRSF039102 3 367 7.5E-120 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 359 41.639 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 SUPERFAMILY SSF52440 5 141 2.78E-36 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Pfam PF07478 D-ala D-ala ligase C-terminus 149 356 3.8E-71 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Pfam PF01820 D-ala D-ala ligase N-terminus 8 131 1.6E-31 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Gene3D G3DSA:3.30.1490.20 157 231 4.8E-77 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 SUPERFAMILY SSF56059 142 364 3.54E-55 T 13-10-2018 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 300 329 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 8 358 7.1E-105 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_0983 a13e71dc223699cadbdacd8ec3191711 376 Gene3D G3DSA:3.40.50.20 2 130 7.5E-39 T 13-10-2018 Spica_1992 6837db2a42f532ded817d0a4e1e0c9c7 226 Gene3D G3DSA:3.60.160.10 1 225 7.3E-76 T 13-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily Spica_1992 6837db2a42f532ded817d0a4e1e0c9c7 226 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 222 8.2E-58 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 Spica_1992 6837db2a42f532ded817d0a4e1e0c9c7 226 Pfam PF01987 Mitochondrial biogenesis AIM24 3 207 1.9E-58 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 Spica_1992 6837db2a42f532ded817d0a4e1e0c9c7 226 SUPERFAMILY SSF51219 1 225 6.54E-63 T 13-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily Spica_2670 c6b37d45cbf4a0768ccda4a9ad97305e 436 Pfam PF01435 Peptidase family M48 214 419 7.6E-39 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Spica_2670 c6b37d45cbf4a0768ccda4a9ad97305e 436 Gene3D G3DSA:3.30.2010.10 210 291 3.2E-31 T 13-10-2018 Spica_2670 c6b37d45cbf4a0768ccda4a9ad97305e 436 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 41 211 8.5E-43 T 13-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 Spica_1550 ba9e72ee8311f19fa8fab3ef1dd6ff2f 73 SUPERFAMILY SSF54786 4 69 4.71E-18 T 13-10-2018 Spica_1550 ba9e72ee8311f19fa8fab3ef1dd6ff2f 73 Gene3D G3DSA:3.30.920.30 7 69 1.7E-17 T 13-10-2018 IPR038570 HicA superfamily Spica_1550 ba9e72ee8311f19fa8fab3ef1dd6ff2f 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 62 3.5E-18 T 13-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Spica_0504 ef3cf67f1ca396d248b4de80eeaaed17 145 Pfam PF01909 Nucleotidyltransferase domain 24 80 1.9E-7 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spica_0504 ef3cf67f1ca396d248b4de80eeaaed17 145 Gene3D G3DSA:3.30.460.10 3 96 5.6E-16 T 13-10-2018 Spica_0504 ef3cf67f1ca396d248b4de80eeaaed17 145 SUPERFAMILY SSF81301 8 102 2.54E-17 T 13-10-2018 Spica_2013 bba66931107ef8044f28b49925257810 338 Gene3D G3DSA:3.40.50.2300 160 301 1.2E-34 T 13-10-2018 Spica_2013 bba66931107ef8044f28b49925257810 338 SUPERFAMILY SSF53822 53 312 1.22E-25 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2013 bba66931107ef8044f28b49925257810 338 Pfam PF13407 Periplasmic binding protein domain 58 313 2.3E-16 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2013 bba66931107ef8044f28b49925257810 338 Gene3D G3DSA:3.40.50.2300 59 312 1.2E-34 T 13-10-2018 Spica_1784 362e35f9578f92b93c88986450ea8a7b 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 35 5.2E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spica_1784 362e35f9578f92b93c88986450ea8a7b 83 SUPERFAMILY SSF47598 1 37 3.71E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1761 362e35f9578f92b93c88986450ea8a7b 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 35 5.2E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spica_1761 362e35f9578f92b93c88986450ea8a7b 83 SUPERFAMILY SSF47598 1 37 3.71E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1778 362e35f9578f92b93c88986450ea8a7b 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 35 5.2E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spica_1778 362e35f9578f92b93c88986450ea8a7b 83 SUPERFAMILY SSF47598 1 37 3.71E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_0416 d5692b2ae4fc71c3dac2ab403c4aa56a 266 Pfam PF00005 ABC transporter 25 194 7.7E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0416 d5692b2ae4fc71c3dac2ab403c4aa56a 266 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 243 265 6.8E-8 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spica_0416 d5692b2ae4fc71c3dac2ab403c4aa56a 266 SMART SM00382 33 242 1.7E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0416 d5692b2ae4fc71c3dac2ab403c4aa56a 266 Gene3D G3DSA:3.40.50.300 3 266 4.5E-57 T 13-10-2018 Spica_0416 d5692b2ae4fc71c3dac2ab403c4aa56a 266 SUPERFAMILY SSF52540 8 264 8.88E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1171 4c06e34311e78a701599affb57c709aa 309 PIRSF PIRSF005261 12 308 1.1E-64 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Spica_1171 4c06e34311e78a701599affb57c709aa 309 SUPERFAMILY SSF118352 248 305 3.4E-16 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Spica_1171 4c06e34311e78a701599affb57c709aa 309 Gene3D G3DSA:3.55.30.10 21 250 5.9E-63 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Spica_1171 4c06e34311e78a701599affb57c709aa 309 Pfam PF01430 Hsp33 protein 21 296 1.8E-75 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Spica_1171 4c06e34311e78a701599affb57c709aa 309 SUPERFAMILY SSF64397 23 258 1.96E-54 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Spica_1171 4c06e34311e78a701599affb57c709aa 309 Gene3D G3DSA:3.90.1280.10 251 307 9.1E-18 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Spica_0771 5e82fc77df36e77bd1224fa2e87084e5 411 Gene3D G3DSA:3.20.20.140 157 339 1.9E-45 T 13-10-2018 Spica_0771 5e82fc77df36e77bd1224fa2e87084e5 411 Pfam PF01979 Amidohydrolase family 178 332 1.2E-26 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Spica_0771 5e82fc77df36e77bd1224fa2e87084e5 411 SUPERFAMILY SSF51556 51 311 3.08E-40 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_2285 8bf04302190526ab8c344ac95c735a53 426 Pfam PF01547 Bacterial extracellular solute-binding protein 51 335 2.6E-40 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2285 8bf04302190526ab8c344ac95c735a53 426 SUPERFAMILY SSF53850 35 420 1.68E-72 T 13-10-2018 Spica_2285 8bf04302190526ab8c344ac95c735a53 426 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 144 161 - T 13-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 Spica_2285 8bf04302190526ab8c344ac95c735a53 426 Gene3D G3DSA:3.40.190.10 31 419 8.5E-72 T 13-10-2018 Spica_0898 2f4eaeca008dd948475c59a8aa1587d3 368 SUPERFAMILY SSF53335 149 231 9.68E-5 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 SUPERFAMILY SSF50494 197 420 1.68E-44 T 13-10-2018 IPR009003 Peptidase S1, PA clan Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 PRINTS PR00834 HtrA/DegQ protease family signature 246 258 1.5E-21 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 PRINTS PR00834 HtrA/DegQ protease family signature 317 341 1.5E-21 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 PRINTS PR00834 HtrA/DegQ protease family signature 349 366 1.5E-21 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 Gene3D G3DSA:2.40.10.10 312 418 1.4E-32 T 13-10-2018 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 Pfam PF13365 Trypsin-like peptidase domain 237 378 4.7E-24 T 13-10-2018 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 SUPERFAMILY SSF50156 385 489 3.2E-5 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_0796 f585ec6133484fe50d90315d3f7a9f6c 602 Gene3D G3DSA:2.40.10.10 196 307 5.1E-13 T 13-10-2018 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 SUPERFAMILY SSF52768 2 299 2.52E-82 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 TIGRFAM TIGR01229 rocF_arginase: arginase 5 300 3.3E-80 T 13-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 Gene3D G3DSA:3.40.800.10 1 302 4.5E-98 T 13-10-2018 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PIRSF PIRSF036979 1 301 5.9E-32 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 Pfam PF00491 Arginase family 3 295 5.5E-67 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 ProSitePatterns PS01053 Arginase family signature. 227 248 - T 13-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PRINTS PR00116 Arginase signature 94 109 1.1E-43 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PRINTS PR00116 Arginase signature 259 273 1.1E-43 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PRINTS PR00116 Arginase signature 224 253 1.1E-43 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PRINTS PR00116 Arginase signature 121 148 1.1E-43 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_0893 b1dc1251ff8a3046d393be0d1435e13e 302 PRINTS PR00116 Arginase signature 175 193 1.1E-43 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 Spica_1703 e16ca5e21705af7a5ab04fbc2b7c83bb 160 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 148 26.142 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 Spica_1703 e16ca5e21705af7a5ab04fbc2b7c83bb 160 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 146 2.4E-29 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 Spica_0021 b95bd990b2129f727c2c183037aecb1b 253 Gene3D G3DSA:3.40.1390.30 99 224 4.8E-72 T 13-10-2018 Spica_0021 b95bd990b2129f727c2c183037aecb1b 253 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 25 240 1.1E-52 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spica_0021 b95bd990b2129f727c2c183037aecb1b 253 Gene3D G3DSA:3.40.1390.30 8 240 4.8E-72 T 13-10-2018 Spica_0021 b95bd990b2129f727c2c183037aecb1b 253 SUPERFAMILY SSF102705 1 249 2.09E-64 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Spica_0021 b95bd990b2129f727c2c183037aecb1b 253 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 251 2.6E-57 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spica_0941 1fecd946504e04daf87a56763a0d5dd9 387 Gene3D G3DSA:1.20.1250.20 1 175 8.6E-17 T 13-10-2018 Spica_0941 1fecd946504e04daf87a56763a0d5dd9 387 Gene3D G3DSA:1.20.1250.20 198 384 2.9E-33 T 13-10-2018 Spica_0941 1fecd946504e04daf87a56763a0d5dd9 387 SUPERFAMILY SSF103473 3 379 7.98E-43 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_0941 1fecd946504e04daf87a56763a0d5dd9 387 Pfam PF12832 MFS_1 like family 2 359 1.6E-38 T 13-10-2018 IPR024989 Major facilitator superfamily associated domain Spica_2575 15871eb0addaced41b4a4c58c312e811 364 PIRSF PIRSF000525 1 363 5.1E-144 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Spica_2575 15871eb0addaced41b4a4c58c312e811 364 Pfam PF00266 Aminotransferase class-V 5 351 6.5E-52 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_2575 15871eb0addaced41b4a4c58c312e811 364 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 362 48.815 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Spica_2575 15871eb0addaced41b4a4c58c312e811 364 Gene3D G3DSA:3.90.1150.10 261 363 6.8E-39 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2575 15871eb0addaced41b4a4c58c312e811 364 SUPERFAMILY SSF53383 3 359 3.57E-107 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2575 15871eb0addaced41b4a4c58c312e811 364 Gene3D G3DSA:3.40.640.10 17 260 8.6E-80 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_2575 15871eb0addaced41b4a4c58c312e811 364 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 362 6.7E-147 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Spica_0002 fe72a670517c0088326460870e99fadb 367 SMART SM00480 17 362 1.8E-108 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 3.9E-102 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 SUPERFAMILY SSF55979 128 244 2.54E-24 T 13-10-2018 Spica_0002 fe72a670517c0088326460870e99fadb 367 Gene3D G3DSA:3.10.150.10 1 242 2.4E-107 T 13-10-2018 Spica_0002 fe72a670517c0088326460870e99fadb 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 9.6E-28 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 SUPERFAMILY SSF55979 245 366 3.14E-32 T 13-10-2018 Spica_0002 fe72a670517c0088326460870e99fadb 367 Gene3D G3DSA:3.70.10.10 138 364 2.4E-107 T 13-10-2018 Spica_0002 fe72a670517c0088326460870e99fadb 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 2.0E-26 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 2.9E-19 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 PIRSF PIRSF000804 1 367 8.9E-108 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Spica_0002 fe72a670517c0088326460870e99fadb 367 SUPERFAMILY SSF55979 1 120 3.77E-19 T 13-10-2018 Spica_0562 d1b7304b5afd195bc3cefb02ac29a6ff 289 SUPERFAMILY SSF55681 3 221 1.49E-37 T 13-10-2018 Spica_0562 d1b7304b5afd195bc3cefb02ac29a6ff 289 Pfam PF03099 Biotin/lipoate A/B protein ligase family 68 167 7.7E-11 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Spica_0562 d1b7304b5afd195bc3cefb02ac29a6ff 289 Gene3D G3DSA:3.30.930.10 53 236 2.2E-39 T 13-10-2018 Spica_0562 d1b7304b5afd195bc3cefb02ac29a6ff 289 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 67 277 4.1E-28 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Spica_1044 df9c8d4d2a4425ae0d8d0e33abb49919 133 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 1.7E-16 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_1044 df9c8d4d2a4425ae0d8d0e33abb49919 133 Gene3D G3DSA:3.40.140.10 1 130 1.6E-46 T 13-10-2018 Spica_1044 df9c8d4d2a4425ae0d8d0e33abb49919 133 SUPERFAMILY SSF53927 1 124 4.25E-40 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Spica_1044 df9c8d4d2a4425ae0d8d0e33abb49919 133 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 4 124 1.4E-40 T 13-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 Spica_1044 df9c8d4d2a4425ae0d8d0e33abb49919 133 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Gene3D G3DSA:1.10.285.10 5 379 8.9E-169 T 13-10-2018 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 444 7.2E-87 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Gene3D G3DSA:3.40.50.10860 54 189 8.9E-169 T 13-10-2018 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 SMART SM00839 203 444 3.7E-86 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 56 184 5.2E-51 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Gene3D G3DSA:1.10.285.10 380 446 1.1E-9 T 13-10-2018 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 Gene3D G3DSA:3.40.50.720 208 371 8.9E-169 T 13-10-2018 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 SUPERFAMILY SSF53223 6 195 2.72E-75 T 13-10-2018 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 SUPERFAMILY SSF51735 201 445 5.25E-73 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 113 127 4.6E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 4.6E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 4.6E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 370 381 4.6E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Spica_0934 10b734a4fa52cd83bd9106a89c541ff8 446 PIRSF PIRSF000185 21 446 2.0E-117 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 Gene3D G3DSA:3.40.50.10890 225 413 1.5E-144 T 13-10-2018 Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 SMART SM01027 257 383 4.5E-57 T 13-10-2018 IPR022712 Beta-Casp domain Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 SUPERFAMILY SSF56281 3 462 1.35E-125 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 Pfam PF10996 Beta-Casp domain 257 383 6.0E-27 T 13-10-2018 IPR022712 Beta-Casp domain Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 Pfam PF00753 Metallo-beta-lactamase superfamily 20 202 1.4E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 SMART SM00849 15 252 2.9E-16 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 Gene3D G3DSA:3.60.15.10 8 440 1.5E-144 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2827 973e1ed4c4abef58455bf1f81dac5f97 470 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 398 454 1.8E-14 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Spica_0699 77a60b668734e400894b6994db785d57 260 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 259 22.443 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_0699 77a60b668734e400894b6994db785d57 260 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 251 4.0E-39 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_0699 77a60b668734e400894b6994db785d57 260 SUPERFAMILY SSF53067 126 255 5.18E-17 T 13-10-2018 Spica_0699 77a60b668734e400894b6994db785d57 260 Pfam PF03309 Type III pantothenate kinase 3 206 2.3E-39 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Spica_0699 77a60b668734e400894b6994db785d57 260 SUPERFAMILY SSF53067 1 121 5.11E-15 T 13-10-2018 Spica_0699 77a60b668734e400894b6994db785d57 260 Gene3D G3DSA:3.30.420.40 91 260 2.5E-38 T 13-10-2018 Spica_0699 77a60b668734e400894b6994db785d57 260 Gene3D G3DSA:3.30.420.40 1 89 6.2E-12 T 13-10-2018 Spica_1419 4e2143d59e85471db4c861acf2320060 284 Pfam PF01148 Cytidylyltransferase family 6 282 1.5E-48 T 13-10-2018 Spica_0556 30d73f3c446ae740c67ca779e121910c 291 SUPERFAMILY SSF52151 5 289 1.62E-53 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Spica_0556 30d73f3c446ae740c67ca779e121910c 291 Gene3D G3DSA:3.40.1090.10 2 128 1.7E-26 T 13-10-2018 Spica_0556 30d73f3c446ae740c67ca779e121910c 291 Gene3D G3DSA:3.40.1090.20 132 227 3.6E-7 T 13-10-2018 Spica_0556 30d73f3c446ae740c67ca779e121910c 291 Pfam PF01734 Patatin-like phospholipase 9 189 8.5E-26 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 27 423 1.4E-147 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 PIRSF PIRSF005572 39 425 5.1E-51 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 Pfam PF00266 Aminotransferase class-V 42 411 2.7E-134 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 Gene3D G3DSA:3.40.640.10 53 311 6.6E-153 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 SUPERFAMILY SSF53383 27 424 4.22E-115 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0321 1dec060b36ab63ab967ba2c1bea86c0c 426 Gene3D G3DSA:3.90.1150.10 29 416 6.6E-153 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_2528 454a4b5f2686068e70d1ef8ed05f47f0 522 SUPERFAMILY SSF53720 20 465 1.57E-120 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Spica_2528 454a4b5f2686068e70d1ef8ed05f47f0 522 Gene3D G3DSA:3.40.309.10 235 431 2.1E-127 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Spica_2528 454a4b5f2686068e70d1ef8ed05f47f0 522 Gene3D G3DSA:3.40.605.10 22 458 2.1E-127 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Spica_2528 454a4b5f2686068e70d1ef8ed05f47f0 522 Pfam PF00171 Aldehyde dehydrogenase family 22 463 2.7E-119 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Spica_0005 061480591a1fa1e500f52314b5576e2e 51 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 24 3.0E-6 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0005 061480591a1fa1e500f52314b5576e2e 51 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 4.8E-25 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0005 061480591a1fa1e500f52314b5576e2e 51 Pfam PF00468 Ribosomal protein L34 1 44 1.8E-22 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0005 061480591a1fa1e500f52314b5576e2e 51 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 13-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0005 061480591a1fa1e500f52314b5576e2e 51 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.708 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0584 89cdb116b5d913025392024698f91331 313 Pfam PF01728 FtsJ-like methyltransferase 153 229 1.0E-8 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Spica_0584 89cdb116b5d913025392024698f91331 313 Gene3D G3DSA:3.40.50.150 145 305 3.3E-45 T 13-10-2018 Spica_0584 89cdb116b5d913025392024698f91331 313 SUPERFAMILY SSF53335 152 254 6.85E-18 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2237 4765915045effd579a0b1ba33927dab8 418 Pfam PF12704 MacB-like periplasmic core domain 24 223 1.5E-14 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Spica_2237 4765915045effd579a0b1ba33927dab8 418 Pfam PF02687 FtsX-like permease family 307 412 3.4E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 Gene3D G3DSA:4.10.520.10 2 100 9.3E-32 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 2.0E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 PRINTS PR01727 Prokaryotic integration host factor signature 80 94 2.0E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 PRINTS PR01727 Prokaryotic integration host factor signature 64 77 2.0E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 SMART SM00411 6 96 4.5E-32 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 71 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 Pfam PF00216 Bacterial DNA-binding protein 6 94 6.8E-27 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Spica_1610 69cc7df53a38b6e9f3383f9ea7757397 112 SUPERFAMILY SSF47729 6 98 2.36E-25 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Spica_0874 450fa5667f770aa0f31491eb256fb4b2 334 SUPERFAMILY SSF53448 34 278 9.55E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0874 450fa5667f770aa0f31491eb256fb4b2 334 Pfam PF00535 Glycosyl transferase family 2 37 159 5.1E-12 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Spica_0874 450fa5667f770aa0f31491eb256fb4b2 334 Gene3D G3DSA:3.90.550.10 2 316 1.4E-90 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 Gene3D G3DSA:1.20.1270.170 165 321 3.3E-103 T 13-10-2018 Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 Hamap MF_01497 Stress response kinase A [srkA]. 4 334 37.17 T 13-10-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 Gene3D G3DSA:1.10.510.10 61 274 3.3E-103 T 13-10-2018 Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 Gene3D G3DSA:3.30.200.70 13 124 3.3E-103 T 13-10-2018 Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 SUPERFAMILY SSF56112 4 329 1.95E-52 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Spica_2811 3e2aad1333a51c8c08935b0eeb4dfbcd 335 Pfam PF01636 Phosphotransferase enzyme family 38 269 8.7E-26 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 Gene3D G3DSA:2.40.30.170 53 228 2.7E-85 T 13-10-2018 Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 SUPERFAMILY SSF111369 58 221 1.57E-12 T 13-10-2018 Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 114 217 6.3E-25 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 114 304 2.6E-40 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 Gene3D G3DSA:2.40.50.100 71 142 2.7E-85 T 13-10-2018 Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 Gene3D G3DSA:2.40.420.20 44 305 2.7E-85 T 13-10-2018 Spica_0191 4444106713dad8c51d0bd1f46826e6e8 315 Pfam PF13533 Biotin-lipoyl like 74 104 2.9E-5 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Pfam PF07724 AAA domain (Cdc48 subfamily) 239 377 7.5E-39 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 58 106 6.1E-6 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 6 492 41.847 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Gene3D G3DSA:1.10.8.60 384 489 6.5E-38 T 13-10-2018 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Gene3D G3DSA:1.10.8.10 270 295 1.5E-24 T 13-10-2018 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 9 492 2.4E-189 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 SUPERFAMILY SSF52540 7 489 2.17E-79 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Gene3D G3DSA:3.40.50.300 7 136 4.8E-34 T 13-10-2018 Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 384 455 3.8E-5 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1674 5fce0b842362975c38fdeda02a27673e 492 SMART SM00382 54 381 2.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1674 5fce0b842362975c38fdeda02a27673e 492 SMART SM01086 384 483 6.2E-22 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Spica_1674 5fce0b842362975c38fdeda02a27673e 492 Gene3D G3DSA:3.40.50.300 269 359 1.5E-24 T 13-10-2018 Spica_0527 7f31d34c143a7c9e365307ab71c6abfe 394 Pfam PF13439 Glycosyltransferase Family 4 22 200 1.2E-6 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_0527 7f31d34c143a7c9e365307ab71c6abfe 394 Gene3D G3DSA:3.40.50.2000 208 370 1.9E-19 T 13-10-2018 Spica_0527 7f31d34c143a7c9e365307ab71c6abfe 394 Pfam PF00534 Glycosyl transferases group 1 216 367 2.0E-15 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_0527 7f31d34c143a7c9e365307ab71c6abfe 394 Gene3D G3DSA:3.40.50.2000 20 207 7.0E-13 T 13-10-2018 Spica_0527 7f31d34c143a7c9e365307ab71c6abfe 394 SUPERFAMILY SSF53756 22 365 8.17E-34 T 13-10-2018 Spica_2238 54a499257751676743d43bb892c2c3c8 504 Pfam PF02687 FtsX-like permease family 390 494 3.9E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_1969 00906987bae82314f317cc8ea638411c 405 SUPERFAMILY SSF51261 191 373 9.42E-41 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1969 00906987bae82314f317cc8ea638411c 405 Gene3D G3DSA:2.70.70.10 222 379 2.9E-37 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1969 00906987bae82314f317cc8ea638411c 405 Pfam PF01551 Peptidase family M23 279 373 5.8E-26 T 13-10-2018 IPR016047 Peptidase M23 Spica_1477 559d8010041c327f68b81b8df856b08d 913 Pfam PF04408 Helicase associated domain (HA2) 425 492 8.4E-7 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Spica_1477 559d8010041c327f68b81b8df856b08d 913 Pfam PF08482 ATP-dependent helicase C-terminal 765 897 1.7E-40 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal Spica_1477 559d8010041c327f68b81b8df856b08d 913 Gene3D G3DSA:3.40.50.300 194 382 8.6E-44 T 13-10-2018 Spica_1477 559d8010041c327f68b81b8df856b08d 913 Pfam PF00271 Helicase conserved C-terminal domain 249 366 4.0E-13 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1477 559d8010041c327f68b81b8df856b08d 913 SMART SM00487 10 199 3.7E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1477 559d8010041c327f68b81b8df856b08d 913 SMART SM00847 424 511 1.6E-8 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Spica_1477 559d8010041c327f68b81b8df856b08d 913 SMART SM00490 265 366 4.0E-16 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1477 559d8010041c327f68b81b8df856b08d 913 Pfam PF00270 DEAD/DEAH box helicase 23 164 4.8E-7 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1477 559d8010041c327f68b81b8df856b08d 913 Gene3D G3DSA:3.40.50.300 2 191 1.9E-52 T 13-10-2018 Spica_1477 559d8010041c327f68b81b8df856b08d 913 SUPERFAMILY SSF52540 24 376 5.06E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 PIRSF PIRSF000726 1 443 2.7E-113 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 Pfam PF00696 Amino acid kinase family 1 277 9.8E-51 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 SUPERFAMILY SSF55021 369 442 1.11E-14 T 13-10-2018 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 Gene3D G3DSA:3.30.70.260 301 441 1.1E-44 T 13-10-2018 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 Gene3D G3DSA:1.20.120.1320 40 132 7.9E-106 T 13-10-2018 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 SUPERFAMILY SSF55021 297 385 4.19E-17 T 13-10-2018 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 442 3.2E-116 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 Gene3D G3DSA:3.30.70.260 309 375 1.1E-44 T 13-10-2018 Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 SUPERFAMILY SSF53633 1 290 5.37E-78 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0947 4d00db55d6621cea1fca3517e5b4eeed 443 Gene3D G3DSA:3.40.1160.10 3 288 7.9E-106 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_2860 2c1ee5c88a5cc32270e2c1e6f23fc3cf 372 Gene3D G3DSA:3.40.1830.10 2 165 4.6E-13 T 13-10-2018 IPR035097 Peptidase M29, N-terminal Spica_2860 2c1ee5c88a5cc32270e2c1e6f23fc3cf 372 SUPERFAMILY SSF144052 1 360 8.11E-107 T 13-10-2018 Spica_2860 2c1ee5c88a5cc32270e2c1e6f23fc3cf 372 Pfam PF02073 Thermophilic metalloprotease (M29) 3 333 1.6E-57 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Spica_1672 572dfaf78347a54b23653eff9acc3abb 152 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 150 1.2E-46 T 13-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 Spica_1672 572dfaf78347a54b23653eff9acc3abb 152 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Spica_1672 572dfaf78347a54b23653eff9acc3abb 152 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 104 147 3.8E-13 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1672 572dfaf78347a54b23653eff9acc3abb 152 Pfam PF00460 Flagella basal body rod protein 7 34 4.0E-8 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Spica_2555 4d00580860a94a740d2e6ad0d133112f 207 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 207 24.187 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2555 4d00580860a94a740d2e6ad0d133112f 207 Gene3D G3DSA:3.40.50.2020 14 206 7.8E-52 T 13-10-2018 Spica_2555 4d00580860a94a740d2e6ad0d133112f 207 Pfam PF00156 Phosphoribosyl transferase domain 63 169 6.3E-14 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_2555 4d00580860a94a740d2e6ad0d133112f 207 SUPERFAMILY SSF53271 14 180 1.56E-34 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_2555 4d00580860a94a740d2e6ad0d133112f 207 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 15 203 1.6E-59 T 13-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Spica_0547 ea4cafad719171f7b2fef18a456ffd57 208 Pfam PF03880 DbpA RNA binding domain 104 174 1.4E-20 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain Spica_0547 ea4cafad719171f7b2fef18a456ffd57 208 SUPERFAMILY SSF54928 142 187 8.16E-5 T 13-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 Spica_0547 ea4cafad719171f7b2fef18a456ffd57 208 Gene3D G3DSA:3.30.70.330 103 178 2.0E-18 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 Pfam PF07568 Histidine kinase 302 377 5.1E-17 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 SMART SM00091 138 203 5.6E-10 T 13-10-2018 IPR000014 PAS domain Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 Gene3D G3DSA:3.30.450.20 135 294 1.7E-20 T 13-10-2018 Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 Pfam PF08448 PAS fold 145 197 2.8E-7 T 13-10-2018 IPR013656 PAS fold-4 Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 234 2.4E-12 T 13-10-2018 IPR000014 PAS domain Spica_0437 1599576aef5ddb97677f8cba3ef18d6d 506 SUPERFAMILY SSF55785 126 198 1.21E-14 T 13-10-2018 IPR035965 PAS domain superfamily Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 SUPERFAMILY SSF51690 140 489 3.09E-110 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 Gene3D G3DSA:3.20.140.10 12 482 3.9E-185 T 13-10-2018 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 Gene3D G3DSA:3.20.20.70 152 320 3.9E-185 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 SUPERFAMILY SSF54675 9 139 6.67E-50 T 13-10-2018 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 478 2.3E-187 T 13-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 156 359 6.3E-9 T 13-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Spica_1893 2388aaa9fbbe8a69f791c286f058f9a6 492 PIRSF PIRSF000484 7 491 5.3E-160 T 13-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 144 1.8E-53 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 Gene3D G3DSA:3.30.1360.80 1 158 1.1E-46 T 13-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 117 136 3.7E-17 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 75 93 3.7E-17 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 48 66 3.7E-17 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 3.7E-17 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 10 139 1.0E-41 T 13-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 Spica_0473 1fd48b6b7bbcb11218edd32a8a3d3d8b 158 SUPERFAMILY SSF63411 3 146 1.28E-43 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 SUPERFAMILY SSF103190 274 402 1.41E-17 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 Gene3D G3DSA:3.20.20.450 1 230 4.1E-47 T 13-10-2018 IPR035919 EAL domain superfamily Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 SUPERFAMILY SSF141868 3 240 8.5E-45 T 13-10-2018 IPR035919 EAL domain superfamily Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 Gene3D G3DSA:3.30.450.20 297 397 4.0E-6 T 13-10-2018 Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 SMART SM00052 1 242 1.9E-11 T 13-10-2018 IPR001633 EAL domain Spica_2127 462a5d5d5a0172d0976d12bc996f7708 428 Pfam PF00563 EAL domain 7 237 1.3E-37 T 13-10-2018 IPR001633 EAL domain Spica_2743 16e168990656b809830fbb506c350ce0 272 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 265 16.406 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spica_2743 16e168990656b809830fbb506c350ce0 272 Pfam PF02673 Bacitracin resistance protein BacA 6 260 2.6E-69 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 Pfam PF01048 Phosphorylase superfamily 16 219 3.2E-40 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 46.447 T 13-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 13-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 SUPERFAMILY SSF53167 2 233 2.09E-91 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 Gene3D G3DSA:3.40.50.1580 1 234 7.4E-73 T 13-10-2018 Spica_0370 cd02f3cfd5afc123c6aea05bcc355a1b 234 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 2.8E-99 T 13-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 Spica_0877 904cba69d19b6e77aa9af7576571883d 156 Pfam PF04073 Aminoacyl-tRNA editing domain 31 145 3.1E-22 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Spica_0877 904cba69d19b6e77aa9af7576571883d 156 PIRSF PIRSF006181 1 156 7.6E-57 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Spica_0877 904cba69d19b6e77aa9af7576571883d 156 Gene3D G3DSA:3.90.960.10 1 155 7.6E-51 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Spica_0877 904cba69d19b6e77aa9af7576571883d 156 SUPERFAMILY SSF55826 4 154 1.57E-39 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Spica_0877 904cba69d19b6e77aa9af7576571883d 156 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 4 154 8.3E-53 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Spica_0524 0b3721020b2d2aaf8f18d8da486bc715 342 Gene3D G3DSA:3.40.50.720 4 308 6.8E-135 T 13-10-2018 Spica_0524 0b3721020b2d2aaf8f18d8da486bc715 342 Gene3D G3DSA:3.90.25.30 166 321 6.8E-135 T 13-10-2018 Spica_0524 0b3721020b2d2aaf8f18d8da486bc715 342 Pfam PF02719 Polysaccharide biosynthesis protein 7 281 2.4E-104 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Spica_0524 0b3721020b2d2aaf8f18d8da486bc715 342 Pfam PF08485 Polysaccharide biosynthesis protein C-terminal 284 331 2.6E-19 T 13-10-2018 IPR013692 UDP-glucose 4-epimerase CapD, C-terminal domain GO:0003978|GO:0009103 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344 Spica_0524 0b3721020b2d2aaf8f18d8da486bc715 342 SUPERFAMILY SSF51735 1 259 4.67E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2826 71ed40fd45eab215a02af3b31c981ecc 242 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 2 238 7.5E-65 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 Spica_2826 71ed40fd45eab215a02af3b31c981ecc 242 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 3 69 2.2E-7 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Spica_2826 71ed40fd45eab215a02af3b31c981ecc 242 Gene3D G3DSA:3.40.1280.10 73 239 5.6E-55 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_2826 71ed40fd45eab215a02af3b31c981ecc 242 SUPERFAMILY SSF75217 81 239 3.14E-47 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_2826 71ed40fd45eab215a02af3b31c981ecc 242 Pfam PF00588 SpoU rRNA Methylase family 93 232 1.3E-41 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 Gene3D G3DSA:3.30.2130.30 1 171 1.1E-42 T 13-10-2018 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 SUPERFAMILY SSF143437 1 170 1.34E-34 T 13-10-2018 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 Pfam PF02926 THUMP domain 45 158 1.4E-11 T 13-10-2018 IPR004114 THUMP domain GO:0003723 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 372 5.0E-98 T 13-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 SMART SM00981 71 162 1.4E-11 T 13-10-2018 IPR004114 THUMP domain GO:0003723 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 394 116.201 T 13-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 172 367 7.6E-68 T 13-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 SUPERFAMILY SSF52402 171 369 1.5E-41 T 13-10-2018 Spica_1317 9aeb929798f6f7322787f80a0188a337 394 Gene3D G3DSA:3.40.50.620 172 385 8.9E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2085 d5be19ef13051543be81863475825ff4 357 Pfam PF06114 IrrE N-terminal-like domain 160 276 2.2E-10 T 13-10-2018 IPR010359 IrrE N-terminal-like domain Spica_2085 d5be19ef13051543be81863475825ff4 357 Pfam PF01381 Helix-turn-helix 11 67 5.1E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2085 d5be19ef13051543be81863475825ff4 357 Gene3D G3DSA:1.10.260.40 1 71 4.2E-16 T 13-10-2018 Spica_2085 d5be19ef13051543be81863475825ff4 357 SMART SM00530 10 67 2.6E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2085 d5be19ef13051543be81863475825ff4 357 SUPERFAMILY SSF47413 2 70 1.86E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_1715 57c4713a518156f25cf73a30d779793c 366 Pfam PF12849 PBP superfamily domain 32 307 1.0E-54 T 13-10-2018 IPR024370 PBP domain Spica_1715 57c4713a518156f25cf73a30d779793c 366 Gene3D G3DSA:3.40.190.10 117 294 1.5E-110 T 13-10-2018 Spica_1715 57c4713a518156f25cf73a30d779793c 366 PIRSF PIRSF002756 1 355 3.0E-108 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Spica_1715 57c4713a518156f25cf73a30d779793c 366 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 40 352 1.0E-107 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Spica_1715 57c4713a518156f25cf73a30d779793c 366 SUPERFAMILY SSF53850 40 356 1.0E-83 T 13-10-2018 Spica_1715 57c4713a518156f25cf73a30d779793c 366 Gene3D G3DSA:3.40.190.10 40 339 1.5E-110 T 13-10-2018 Spica_0124 e9dac6e0f8bb35320772cc31d60f9c2f 418 Gene3D G3DSA:3.40.190.10 25 417 6.0E-46 T 13-10-2018 Spica_0124 e9dac6e0f8bb35320772cc31d60f9c2f 418 SUPERFAMILY SSF53850 27 343 2.11E-36 T 13-10-2018 Spica_0124 e9dac6e0f8bb35320772cc31d60f9c2f 418 Pfam PF01547 Bacterial extracellular solute-binding protein 33 311 4.2E-18 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1810 16c4faf0fceefb52318140488558dea3 250 Gene3D G3DSA:3.90.230.10 1 250 2.2E-89 T 13-10-2018 Spica_1810 16c4faf0fceefb52318140488558dea3 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 4.7E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1810 16c4faf0fceefb52318140488558dea3 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 4.7E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1810 16c4faf0fceefb52318140488558dea3 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 4.7E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1810 16c4faf0fceefb52318140488558dea3 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 4.7E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1810 16c4faf0fceefb52318140488558dea3 250 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 249 8.1E-85 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1810 16c4faf0fceefb52318140488558dea3 250 Pfam PF00557 Metallopeptidase family M24 12 240 1.2E-43 T 13-10-2018 IPR000994 Peptidase M24 Spica_1810 16c4faf0fceefb52318140488558dea3 250 SUPERFAMILY SSF55920 1 249 2.49E-73 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Spica_1810 16c4faf0fceefb52318140488558dea3 250 Hamap MF_01974 Methionine aminopeptidase [map]. 2 250 35.602 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Spica_1012 c90194d0d7394da67c4a393eed799c6b 166 Gene3D G3DSA:1.10.3210.10 10 129 8.9E-7 T 13-10-2018 Spica_1012 c90194d0d7394da67c4a393eed799c6b 166 SUPERFAMILY SSF109604 19 154 5.14E-11 T 13-10-2018 Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Pfam PF13091 PLD-like domain 35 183 3.3E-12 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Pfam PF00271 Helicase conserved C-terminal domain 689 807 8.3E-14 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 SUPERFAMILY SSF52540 201 454 3.29E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 365 374 - T 13-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 SUPERFAMILY SSF56024 114 187 1.41E-7 T 13-10-2018 Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Gene3D G3DSA:3.30.870.10 37 185 9.0E-7 T 13-10-2018 Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Gene3D G3DSA:3.40.50.10810 232 450 8.3E-43 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 SMART SM00490 714 807 2.6E-12 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 SUPERFAMILY SSF52540 362 854 2.13E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Gene3D G3DSA:3.40.50.300 632 839 4.1E-30 T 13-10-2018 Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 SMART SM00487 231 450 1.8E-8 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_2084 19790d895f0de7026f1cfe3f5478794c 911 Pfam PF00176 SNF2 family N-terminal domain 258 437 2.8E-10 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spica_1928 988e2ee5d7e2ff51cf64099fc5e35550 222 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 7 216 7.0E-53 T 13-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Spica_1928 988e2ee5d7e2ff51cf64099fc5e35550 222 Gene3D G3DSA:3.30.70.2660 1 222 2.2E-87 T 13-10-2018 Spica_1928 988e2ee5d7e2ff51cf64099fc5e35550 222 PIRSF PIRSF029950 1 222 3.3E-81 T 13-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 Spica_1928 988e2ee5d7e2ff51cf64099fc5e35550 222 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 214 4.5E-43 T 13-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 Spica_1928 988e2ee5d7e2ff51cf64099fc5e35550 222 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 7 46 7.6E-17 T 13-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal Spica_1042 b8aed62fbd09a581c58d231a341afffd 292 Pfam PF01551 Peptidase family M23 59 143 5.7E-6 T 13-10-2018 IPR016047 Peptidase M23 Spica_1042 b8aed62fbd09a581c58d231a341afffd 292 Gene3D G3DSA:2.70.70.10 21 154 2.2E-9 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_1042 b8aed62fbd09a581c58d231a341afffd 292 SUPERFAMILY SSF51261 26 151 1.31E-6 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 132 138 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 SUPERFAMILY SSF53335 98 475 2.05E-69 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 PIRSF PIRSF015855 1 633 2.6E-191 T 13-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 Pfam PF01555 DNA methylase 129 450 2.5E-42 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 420 434 4.2E-15 T 13-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 129 141 4.2E-15 T 13-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 192 211 4.2E-15 T 13-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Spica_0102 27b434da7b2f796fdb95bbc579ac681d 633 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 397 419 4.2E-15 T 13-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 Spica_0423 e014c3e5749ab1ce02a65e95dd9fde0c 403 SUPERFAMILY SSF51556 5 394 1.4E-62 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_0423 e014c3e5749ab1ce02a65e95dd9fde0c 403 Pfam PF00962 Adenosine/AMP deaminase 190 384 2.7E-32 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 Spica_0423 e014c3e5749ab1ce02a65e95dd9fde0c 403 Pfam PF00962 Adenosine/AMP deaminase 12 135 3.6E-20 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 Spica_0423 e014c3e5749ab1ce02a65e95dd9fde0c 403 Gene3D G3DSA:3.20.20.140 2 396 5.0E-93 T 13-10-2018 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 ProSitePatterns PS01048 Ribosomal protein S6 signature. 42 51 - T 13-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 Pfam PF01250 Ribosomal protein S6 3 90 1.8E-19 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 93 16.948 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 Gene3D G3DSA:3.30.70.60 1 93 9.0E-26 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 3.7E-21 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1429 b4b1e72ce4ee2970fef7dc3ab400c22b 93 SUPERFAMILY SSF54995 1 93 9.55E-24 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 Gene3D G3DSA:3.40.50.12780 299 500 1.4E-40 T 13-10-2018 Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 Gene3D G3DSA:3.40.50.12780 3 298 1.4E-43 T 13-10-2018 Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 SUPERFAMILY SSF56801 10 560 3.01E-107 T 13-10-2018 Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 Pfam PF00501 AMP-binding enzyme 35 506 5.1E-97 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_0294 d65edb82b1a13d240c073c59dee68fce 637 Gene3D G3DSA:3.30.300.30 501 599 3.5E-5 T 13-10-2018 Spica_2355 a9b90220fc635db833f9f16c0efea5d4 230 SUPERFAMILY SSF82649 55 101 1.39E-8 T 13-10-2018 Spica_2355 a9b90220fc635db833f9f16c0efea5d4 230 Gene3D G3DSA:3.90.1010.10 33 118 6.9E-7 T 13-10-2018 Spica_2355 a9b90220fc635db833f9f16c0efea5d4 230 Pfam PF01592 NifU-like N terminal domain 56 113 2.1E-4 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Spica_0226 2428180ed135459eef82ddc088c34748 264 SUPERFAMILY SSF46565 181 254 4.97E-18 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_0226 2428180ed135459eef82ddc088c34748 264 Gene3D G3DSA:1.10.287.110 172 259 6.0E-16 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_0226 2428180ed135459eef82ddc088c34748 264 PRINTS PR00625 DnaJ domain signature 196 214 7.9E-9 T 13-10-2018 IPR001623 DnaJ domain Spica_0226 2428180ed135459eef82ddc088c34748 264 PRINTS PR00625 DnaJ domain signature 236 256 7.9E-9 T 13-10-2018 IPR001623 DnaJ domain Spica_0226 2428180ed135459eef82ddc088c34748 264 PRINTS PR00625 DnaJ domain signature 214 229 7.9E-9 T 13-10-2018 IPR001623 DnaJ domain Spica_0226 2428180ed135459eef82ddc088c34748 264 Pfam PF00226 DnaJ domain 197 254 1.1E-13 T 13-10-2018 IPR001623 DnaJ domain Spica_0226 2428180ed135459eef82ddc088c34748 264 SMART SM00271 193 256 7.8E-17 T 13-10-2018 IPR001623 DnaJ domain Spica_1789 287fb888d0c6ce4adb2900a5f6c4d864 258 Pfam PF02517 CAAX protease self-immunity 158 244 7.0E-12 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 16 476 2.1E-133 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Gene3D G3DSA:3.40.1190.10 106 331 3.9E-45 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Gene3D G3DSA:3.40.50.720 8 103 1.7E-23 T 13-10-2018 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 SUPERFAMILY SSF53623 118 305 1.57E-37 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 SUPERFAMILY SSF53244 333 478 1.15E-36 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Gene3D G3DSA:3.90.190.20 332 488 7.9E-51 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Pfam PF01225 Mur ligase family, catalytic domain 15 112 3.2E-19 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 13 482 33.004 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Pfam PF08245 Mur ligase middle domain 121 302 3.6E-17 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 SUPERFAMILY SSF51984 14 103 1.7E-19 T 13-10-2018 Spica_1579 10f9174a14b2ec9e9ffbebf5e9130035 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 335 416 1.0E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Spica_0671 366079e23a209a9e735337444e37ad7d 411 Pfam PF00027 Cyclic nucleotide-binding domain 10 98 5.7E-17 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0671 366079e23a209a9e735337444e37ad7d 411 Pfam PF00027 Cyclic nucleotide-binding domain 197 280 1.3E-25 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0671 366079e23a209a9e735337444e37ad7d 411 Gene3D G3DSA:2.60.120.10 4 126 6.8E-23 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0671 366079e23a209a9e735337444e37ad7d 411 SUPERFAMILY SSF51206 196 307 1.96E-32 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0671 366079e23a209a9e735337444e37ad7d 411 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 245 262 - T 13-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0671 366079e23a209a9e735337444e37ad7d 411 SUPERFAMILY SSF51206 10 116 1.05E-20 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0671 366079e23a209a9e735337444e37ad7d 411 Gene3D G3DSA:2.60.120.10 188 306 1.3E-34 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0671 366079e23a209a9e735337444e37ad7d 411 SMART SM00100 1 110 8.2E-4 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0671 366079e23a209a9e735337444e37ad7d 411 SMART SM00100 176 295 2.0E-23 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0671 366079e23a209a9e735337444e37ad7d 411 PRINTS PR00103 cAMP-dependent protein kinase signature 255 266 3.5E-8 T 13-10-2018 Spica_0671 366079e23a209a9e735337444e37ad7d 411 PRINTS PR00103 cAMP-dependent protein kinase signature 243 252 3.5E-8 T 13-10-2018 Spica_0671 366079e23a209a9e735337444e37ad7d 411 PRINTS PR00103 cAMP-dependent protein kinase signature 276 288 3.5E-8 T 13-10-2018 Spica_0671 366079e23a209a9e735337444e37ad7d 411 PRINTS PR00103 cAMP-dependent protein kinase signature 214 228 3.5E-8 T 13-10-2018 Spica_0671 366079e23a209a9e735337444e37ad7d 411 PRINTS PR00103 cAMP-dependent protein kinase signature 199 213 3.5E-8 T 13-10-2018 Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 SUPERFAMILY SSF52540 6 237 6.99E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 Pfam PF00005 ABC transporter 23 176 1.9E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 Pfam PF00005 ABC transporter 278 432 1.5E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 Gene3D G3DSA:3.40.50.300 261 501 1.3E-42 T 13-10-2018 Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 SMART SM00382 32 224 6.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 SMART SM00382 286 481 0.0056 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 Gene3D G3DSA:3.40.50.300 2 252 2.0E-55 T 13-10-2018 Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 SUPERFAMILY SSF52540 263 485 2.91E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1865 8fa186855736b5613133aaa58ac29e2e 504 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2144 c3edc0abd2855630517fda096c42bfb6 234 Gene3D G3DSA:3.90.870.10 1 232 6.5E-39 T 13-10-2018 Spica_2144 c3edc0abd2855630517fda096c42bfb6 234 SUPERFAMILY SSF55821 4 150 1.53E-29 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_2144 c3edc0abd2855630517fda096c42bfb6 234 Pfam PF01300 Telomere recombination 21 150 1.4E-25 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 SUPERFAMILY SSF53067 229 465 1.13E-34 T 13-10-2018 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 240 417 2.0E-17 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 Gene3D G3DSA:3.30.420.40 1 218 5.2E-36 T 13-10-2018 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 Gene3D G3DSA:3.30.420.40 220 468 1.1E-46 T 13-10-2018 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 PIRSF PIRSF000538 4 468 4.7E-68 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 227 2.7E-17 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_0274 c10b80785641428055cfa8e9fa73f6a8 468 SUPERFAMILY SSF53067 6 230 9.97E-31 T 13-10-2018 Spica_0676 d9439f30d7e1a05e447186802f5ec96d 246 Gene3D G3DSA:3.60.21.10 1 246 4.9E-61 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_0676 d9439f30d7e1a05e447186802f5ec96d 246 SUPERFAMILY SSF56300 1 245 3.34E-45 T 13-10-2018 Spica_0676 d9439f30d7e1a05e447186802f5ec96d 246 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 213 6.8E-20 T 13-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Spica_0676 d9439f30d7e1a05e447186802f5ec96d 246 PIRSF PIRSF000883 1 245 1.0E-44 T 13-10-2018 IPR011152 Phosphoesterase MJ0912 Spica_1961 e43eef1038af9094ed84831fcec465be 704 SMART SM00490 510 595 1.1E-20 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1961 e43eef1038af9094ed84831fcec465be 704 SUPERFAMILY SSF52540 178 454 1.12E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1961 e43eef1038af9094ed84831fcec465be 704 Pfam PF00270 DEAD/DEAH box helicase 297 435 1.4E-16 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1961 e43eef1038af9094ed84831fcec465be 704 Gene3D G3DSA:2.40.50.140 46 140 1.9E-10 T 13-10-2018 Spica_1961 e43eef1038af9094ed84831fcec465be 704 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 670 1.4E-223 T 13-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 Spica_1961 e43eef1038af9094ed84831fcec465be 704 SUPERFAMILY SSF50249 4 172 1.88E-35 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1961 e43eef1038af9094ed84831fcec465be 704 Gene3D G3DSA:3.40.50.300 227 452 3.1E-80 T 13-10-2018 Spica_1961 e43eef1038af9094ed84831fcec465be 704 SMART SM00487 271 461 9.0E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1961 e43eef1038af9094ed84831fcec465be 704 Pfam PF17191 RecG wedge domain 9 168 2.0E-23 T 13-10-2018 IPR033454 RecG, wedge domain Spica_1961 e43eef1038af9094ed84831fcec465be 704 SUPERFAMILY SSF52540 395 605 2.03E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1961 e43eef1038af9094ed84831fcec465be 704 Pfam PF00271 Helicase conserved C-terminal domain 480 594 1.0E-15 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1961 e43eef1038af9094ed84831fcec465be 704 Gene3D G3DSA:3.40.50.300 459 636 2.9E-57 T 13-10-2018 Spica_0752 f64569cb038e94599c16c980d766030d 408 Pfam PF01546 Peptidase family M20/M25/M40 90 405 1.5E-33 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 Spica_0752 f64569cb038e94599c16c980d766030d 408 SUPERFAMILY SSF53187 1 406 1.28E-58 T 13-10-2018 Spica_0752 f64569cb038e94599c16c980d766030d 408 Gene3D G3DSA:3.40.630.10 21 393 8.2E-75 T 13-10-2018 Spica_0752 f64569cb038e94599c16c980d766030d 408 Gene3D G3DSA:3.30.70.360 203 325 8.2E-75 T 13-10-2018 Spica_0752 f64569cb038e94599c16c980d766030d 408 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 34 399 1.7E-71 T 13-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase Spica_0752 f64569cb038e94599c16c980d766030d 408 Pfam PF07687 Peptidase dimerisation domain 199 310 3.7E-17 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain Spica_0752 f64569cb038e94599c16c980d766030d 408 SUPERFAMILY SSF55031 205 318 2.69E-19 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Spica_1902 5f71d9a69531bdcd0e1f99b46e9fca34 251 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 78 1.4E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_1902 5f71d9a69531bdcd0e1f99b46e9fca34 251 SUPERFAMILY SSF46689 25 96 2.36E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_1902 5f71d9a69531bdcd0e1f99b46e9fca34 251 Gene3D G3DSA:1.10.357.10 29 108 4.8E-12 T 13-10-2018 Spica_1238 1324f26b90da43e86414da85935cec22 436 Pfam PF02687 FtsX-like permease family 297 425 1.1E-5 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_1238 1324f26b90da43e86414da85935cec22 436 Pfam PF12704 MacB-like periplasmic core domain 32 205 1.7E-13 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Spica_1328 f368c3f5b9376225fe762d55c8b1690d 372 Gene3D G3DSA:3.90.25.10 220 349 3.2E-127 T 13-10-2018 Spica_1328 f368c3f5b9376225fe762d55c8b1690d 372 SUPERFAMILY SSF51735 5 366 1.27E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1328 f368c3f5b9376225fe762d55c8b1690d 372 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 342 6.2E-101 T 13-10-2018 IPR016040 NAD(P)-binding domain Spica_1328 f368c3f5b9376225fe762d55c8b1690d 372 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 7 355 1.8E-143 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Spica_1328 f368c3f5b9376225fe762d55c8b1690d 372 Gene3D G3DSA:3.40.50.720 7 341 3.2E-127 T 13-10-2018 Spica_0113 15a82fc63ca888d6b128d3289ff28e73 623 SUPERFAMILY SSF56112 43 209 4.51E-9 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Spica_0673 562a316deb2160d377c6725622e43912 157 Pfam PF02643 Uncharacterized ACR, COG1430 51 152 6.4E-31 T 13-10-2018 IPR003795 Protein of unknown function DUF192 Spica_0673 562a316deb2160d377c6725622e43912 157 Gene3D G3DSA:2.60.120.1140 32 156 7.3E-39 T 13-10-2018 IPR038695 Saro_0823-like superfamily Spica_1668 f379f5097184069cc71cebca81bec875 316 SUPERFAMILY SSF160527 201 299 7.45E-6 T 13-10-2018 Spica_1668 f379f5097184069cc71cebca81bec875 316 Pfam PF02108 Flagellar assembly protein FliH 167 294 3.1E-27 T 13-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 SUPERFAMILY SSF46548 5 154 5.62E-37 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 128 3.8E-24 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.3E-16 T 13-10-2018 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 PRINTS PR00419 Adrenodoxin reductase family signature 300 314 1.3E-16 T 13-10-2018 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.3E-16 T 13-10-2018 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 482 2.5E-173 T 13-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 Gene3D G3DSA:1.10.1060.10 8 142 1.6E-24 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 SUPERFAMILY SSF51971 142 418 6.83E-60 T 13-10-2018 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 Gene3D G3DSA:3.50.50.60 258 417 1.0E-36 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 Gene3D G3DSA:3.40.50.720 143 257 1.4E-15 T 13-10-2018 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.6E-25 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_1858 862db5c15ef27251b857bb70c2233aa4 485 SUPERFAMILY SSF51971 377 482 9.77E-8 T 13-10-2018 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 14 458 36.786 T 13-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 Gene3D G3DSA:2.40.50.140 22 110 1.9E-22 T 13-10-2018 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 Pfam PF00152 tRNA synthetases class II (D, K and N) 126 452 2.7E-71 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 32 458 2.3E-111 T 13-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 SUPERFAMILY SSF55681 107 456 3.55E-71 T 13-10-2018 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 1.5E-17 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 PRINTS PR01042 Aspartyl-tRNA synthetase signature 413 427 1.5E-17 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 1.5E-17 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 PRINTS PR01042 Aspartyl-tRNA synthetase signature 373 389 1.5E-17 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 SUPERFAMILY SSF50249 31 112 6.0E-21 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 Gene3D G3DSA:3.30.930.10 115 447 1.2E-85 T 13-10-2018 Spica_0990 06741fbb6b2a069ca5b9a1e57fbece2d 458 Pfam PF01336 OB-fold nucleic acid binding domain 35 103 4.7E-9 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Spica_0970 8bc4ce9b1df91ad6e109ea8254700a18 174 Pfam PF04143 Sulphur transport 5 163 2.6E-35 T 13-10-2018 IPR007272 Sulphur transport domain Spica_0116 a9f5d09876c1f8ca6e8e9dbfc71db120 383 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 224 379 1.7E-38 T 13-10-2018 IPR000160 GGDEF domain Spica_0116 a9f5d09876c1f8ca6e8e9dbfc71db120 383 Gene3D G3DSA:3.30.70.270 219 382 4.4E-44 T 13-10-2018 Spica_0116 a9f5d09876c1f8ca6e8e9dbfc71db120 383 SUPERFAMILY SSF55073 230 379 1.33E-37 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0116 a9f5d09876c1f8ca6e8e9dbfc71db120 383 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 379 4.7E-38 T 13-10-2018 IPR000160 GGDEF domain Spica_0116 a9f5d09876c1f8ca6e8e9dbfc71db120 383 SMART SM00267 213 383 4.2E-35 T 13-10-2018 IPR000160 GGDEF domain Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 Gene3D G3DSA:1.20.140.70 26 180 6.6E-38 T 13-10-2018 Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 Pfam PF08439 Oligopeptidase F 116 184 3.1E-20 T 13-10-2018 IPR013647 Oligopeptidase F, N-terminal domain Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 9 595 1.0E-204 T 13-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 Pfam PF01432 Peptidase family M3 204 585 4.8E-70 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 Gene3D G3DSA:1.10.287.830 182 226 2.8E-9 T 13-10-2018 Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 SUPERFAMILY SSF55486 4 581 1.73E-110 T 13-10-2018 Spica_0722 9bef0ae781f7e57aaa84d12480e351ad 599 Gene3D G3DSA:1.10.1370.20 228 599 1.4E-130 T 13-10-2018 Spica_2020 61a680aa54a4694612ee14fc791b31e7 186 SUPERFAMILY SSF144091 8 182 5.75E-25 T 13-10-2018 Spica_2020 61a680aa54a4694612ee14fc791b31e7 186 Pfam PF01694 Rhomboid family 52 181 1.2E-17 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spica_2020 61a680aa54a4694612ee14fc791b31e7 186 Gene3D G3DSA:1.20.1540.10 2 186 7.0E-23 T 13-10-2018 IPR035952 Rhomboid-like superfamily Spica_1597 60ac45187fa134bec37b120dfa16a361 364 Hamap MF_01841 Agmatine deiminase [aguA]. 10 358 46.619 T 13-10-2018 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 Spica_1597 60ac45187fa134bec37b120dfa16a361 364 Gene3D G3DSA:3.75.10.10 13 364 1.1E-120 T 13-10-2018 Spica_1597 60ac45187fa134bec37b120dfa16a361 364 SUPERFAMILY SSF55909 10 358 6.78E-120 T 13-10-2018 Spica_1597 60ac45187fa134bec37b120dfa16a361 364 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 19 357 4.8E-114 T 13-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 123 21.756 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 123 2.6E-25 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 Gene3D G3DSA:3.90.470.20 1 124 7.8E-31 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 124 4.3E-21 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 114 6.4E-17 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 122 2.0E-30 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Spica_1203 f1230cb02e8f165e7183c4d1d73e29e9 133 SUPERFAMILY SSF56214 2 122 3.79E-25 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Spica_1207 1c32f04c68aa6fc41455a5580690d031 339 Gene3D G3DSA:1.10.3470.10 3 338 7.7E-102 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_1207 1c32f04c68aa6fc41455a5580690d031 339 SUPERFAMILY SSF81345 3 332 3.01E-81 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_1207 1c32f04c68aa6fc41455a5580690d031 339 Pfam PF01032 FecCD transport family 17 332 9.7E-89 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 SMART SM00478 49 197 1.9E-41 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 Gene3D G3DSA:1.10.340.30 31 143 9.2E-59 T 13-10-2018 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 SUPERFAMILY SSF48150 15 200 4.08E-52 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 Pfam PF00633 Helix-hairpin-helix motif 109 138 5.4E-11 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 165 6.9E-11 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 ProSitePatterns PS01155 Endonuclease III family signature. 112 141 - T 13-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 Spica_1575 74c67a53802fe9085d3f00e2c0763874 279 Gene3D G3DSA:1.10.1670.10 23 199 9.2E-59 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 SUPERFAMILY SSF117070 7 139 7.85E-22 T 13-10-2018 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 22 132 3.0E-4 T 13-10-2018 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 Gene3D G3DSA:2.60.40.1820 20 153 1.1E-19 T 13-10-2018 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 Gene3D G3DSA:2.60.40.1820 209 320 1.8E-5 T 13-10-2018 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 Pfam PF03168 Late embryogenesis abundant protein 48 112 1.6E-8 T 13-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 SMART SM00769 27 144 1.3E-4 T 13-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 Spica_0812 a121f4686a1ae10d7eb381e9ceedb959 321 SUPERFAMILY SSF117070 214 300 1.28E-5 T 13-10-2018 Spica_1318 fb1818709674abc05eafd9515e6693ae 473 Gene3D G3DSA:1.10.260.50 104 372 8.4E-103 T 13-10-2018 Spica_1318 fb1818709674abc05eafd9515e6693ae 473 Gene3D G3DSA:3.90.1150.10 94 465 8.4E-103 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1318 fb1818709674abc05eafd9515e6693ae 473 Gene3D G3DSA:3.40.640.10 147 326 8.4E-103 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1318 fb1818709674abc05eafd9515e6693ae 473 PIRSF PIRSF005572 90 473 6.4E-94 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Spica_1318 fb1818709674abc05eafd9515e6693ae 473 SUPERFAMILY SSF53383 92 470 5.36E-75 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1318 fb1818709674abc05eafd9515e6693ae 473 Pfam PF00266 Aminotransferase class-V 94 462 1.2E-51 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_2230 e44f5a0942225f6c88e52621419b161b 56 SUPERFAMILY SSF53822 7 53 3.57E-5 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 SUPERFAMILY SSF51569 9 332 1.76E-97 T 13-10-2018 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 9 332 1.5E-116 T 13-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 PIRSF PIRSF001359 7 332 4.3E-87 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 332 3.9E-82 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 Gene3D G3DSA:3.20.20.70 1 332 5.9E-122 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 84 95 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spica_1695 f593dabec4128c7bd818c2007b9ee9be 332 Pfam PF01116 Fructose-bisphosphate aldolase class-II 10 331 1.5E-97 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Spica_2348 25af890cfdeadcb075a4460378082711 358 PRINTS PR00069 Aldo-keto reductase signature 253 277 2.3E-42 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 PRINTS PR00069 Aldo-keto reductase signature 119 137 2.3E-42 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 PRINTS PR00069 Aldo-keto reductase signature 204 233 2.3E-42 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 PRINTS PR00069 Aldo-keto reductase signature 55 79 2.3E-42 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 PRINTS PR00069 Aldo-keto reductase signature 170 187 2.3E-42 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 SUPERFAMILY SSF51430 22 327 6.94E-77 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_2348 25af890cfdeadcb075a4460378082711 358 Gene3D G3DSA:3.20.20.100 21 335 1.3E-95 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_2348 25af890cfdeadcb075a4460378082711 358 Pfam PF00248 Aldo/keto reductase family 32 319 7.9E-51 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Spica_2348 25af890cfdeadcb075a4460378082711 358 PIRSF PIRSF000097 18 338 6.4E-86 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_2348 25af890cfdeadcb075a4460378082711 358 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 59 76 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 Spica_2257 d3765b2a2d55e95e054f2f13d9850d17 323 Pfam PF00294 pfkB family carbohydrate kinase 2 313 6.1E-44 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_2257 d3765b2a2d55e95e054f2f13d9850d17 323 SUPERFAMILY SSF53613 2 319 3.43E-62 T 13-10-2018 IPR029056 Ribokinase-like Spica_2257 d3765b2a2d55e95e054f2f13d9850d17 323 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spica_2257 d3765b2a2d55e95e054f2f13d9850d17 323 Gene3D G3DSA:3.40.1190.20 1 318 4.4E-76 T 13-10-2018 IPR029056 Ribokinase-like Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 SMART SM00091 13 78 1.4E-6 T 13-10-2018 IPR000014 PAS domain Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 SMART SM00331 159 378 4.6E-17 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 SUPERFAMILY SSF81606 188 376 6.41E-8 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 Pfam PF13426 PAS domain 24 136 5.7E-12 T 13-10-2018 IPR000014 PAS domain Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 Gene3D G3DSA:3.60.40.10 137 378 1.7E-46 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 189 377 1.1E-32 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 58 2.5E-9 T 13-10-2018 IPR000014 PAS domain Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 SUPERFAMILY SSF55785 17 132 6.11E-20 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2327 9bbf32e88c570ad5e3be3d5683dab373 384 Gene3D G3DSA:3.30.450.20 14 136 5.5E-21 T 13-10-2018 Spica_0131 a1c787cfa50180d407355ba726185e24 334 SUPERFAMILY SSF159245 21 201 3.14E-13 T 13-10-2018 Spica_0131 a1c787cfa50180d407355ba726185e24 334 Pfam PF14249 Tocopherol cyclase 129 324 3.8E-12 T 13-10-2018 IPR025893 Tocopherol cyclase GO:0009976 Spica_0458 f8119aace1f56b3f92c5d7c5e3cbee54 222 SUPERFAMILY SSF52833 3 110 2.64E-9 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0458 f8119aace1f56b3f92c5d7c5e3cbee54 222 Gene3D G3DSA:3.40.30.10 2 107 1.5E-16 T 13-10-2018 Spica_1252 ad1a8580500e2ba807a62098dae7dc8b 159 Pfam PF06695 Putative small multi-drug export protein 19 140 4.4E-35 T 13-10-2018 IPR009577 Putative small multi-drug export Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 Gene3D G3DSA:1.10.357.10 60 202 1.4E-15 T 13-10-2018 Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 Gene3D G3DSA:1.10.10.60 10 59 2.8E-15 T 13-10-2018 Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 SUPERFAMILY SSF46689 3 77 5.13E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.6E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 SUPERFAMILY SSF48498 85 201 1.68E-9 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0078 d2caba828a2a239a15164229c2ffc9ce 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 Gene3D G3DSA:3.30.470.10 40 187 2.1E-34 T 13-10-2018 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 ProSitePatterns PS00770 Aminotransferases class-IV signature. 241 271 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 Pfam PF01063 Amino-transferase class IV 69 316 5.8E-37 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 SUPERFAMILY SSF56752 35 357 4.84E-80 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 65 360 6.8E-82 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 Gene3D G3DSA:3.20.10.10 188 360 2.6E-56 T 13-10-2018 Spica_2392 2f2fcac117ad883fc8ec93411b0aa8ee 360 PIRSF PIRSF006468 56 360 1.3E-79 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 Spica_0924 aa5f6354463d4ad0ddd64c34c8c3843d 143 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 136 1.9E-41 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 Spica_0924 aa5f6354463d4ad0ddd64c34c8c3843d 143 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 2 138 23.091 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 Spica_0924 aa5f6354463d4ad0ddd64c34c8c3843d 143 SUPERFAMILY SSF48013 3 137 2.49E-39 T 13-10-2018 IPR035926 NusB-like superfamily Spica_0924 aa5f6354463d4ad0ddd64c34c8c3843d 143 Pfam PF01029 NusB family 5 134 1.5E-36 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Spica_0924 aa5f6354463d4ad0ddd64c34c8c3843d 143 Gene3D G3DSA:1.10.940.10 1 140 2.8E-43 T 13-10-2018 IPR035926 NusB-like superfamily Spica_1793 c92186b3be1731916318f1f2dd465d0c 132 Gene3D G3DSA:3.40.50.1010 1 127 6.4E-24 T 13-10-2018 Spica_1793 c92186b3be1731916318f1f2dd465d0c 132 Pfam PF01850 PIN domain 3 123 1.2E-7 T 13-10-2018 IPR002716 PIN domain Spica_1793 c92186b3be1731916318f1f2dd465d0c 132 SUPERFAMILY SSF88723 3 129 9.53E-14 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 SMART SM00434 2 435 9.4E-124 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 Gene3D G3DSA:3.30.1360.40 205 295 2.9E-114 T 13-10-2018 Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 Gene3D G3DSA:3.90.199.10 23 450 2.9E-114 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 Gene3D G3DSA:1.10.268.10 332 429 2.9E-114 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 23 435 5.3E-113 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_1623 0f8e00e6fbdc5e525cdb096151b4302c 640 SUPERFAMILY SSF56719 5 462 4.19E-109 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 PRINTS PR01467 Bacterial arginine repressor signature 120 135 3.2E-15 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 PRINTS PR01467 Bacterial arginine repressor signature 22 35 3.2E-15 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 PRINTS PR01467 Bacterial arginine repressor signature 38 53 3.2E-15 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 PRINTS PR01467 Bacterial arginine repressor signature 90 103 3.2E-15 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 Gene3D G3DSA:3.30.1360.40 75 151 5.5E-17 T 13-10-2018 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 Hamap MF_00173 Arginine repressor [argR]. 1 155 42.987 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 Pfam PF02863 Arginine repressor, C-terminal domain 85 149 2.0E-21 T 13-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 SUPERFAMILY SSF46785 4 70 2.45E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 SUPERFAMILY SSF55252 86 148 4.32E-12 T 13-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 Pfam PF01316 Arginine repressor, DNA binding domain 4 69 3.1E-17 T 13-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 Spica_1167 4179a1bb0f217c83ce8a1a06fd9bc6d5 157 Gene3D G3DSA:1.10.10.10 6 68 2.7E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1444 680f5eb861cdea7044e10f1121ababe9 439 Pfam PF05036 Sporulation related domain 364 435 1.4E-6 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Spica_1444 680f5eb861cdea7044e10f1121ababe9 439 Gene3D G3DSA:2.40.40.10 23 108 8.6E-7 T 13-10-2018 IPR036908 RlpA-like domain superfamily Spica_1444 680f5eb861cdea7044e10f1121ababe9 439 SUPERFAMILY SSF110997 364 436 3.53E-7 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Spica_1559 e908e6abb8ac991b417e87dfd83a948e 247 Gene3D G3DSA:3.20.20.150 16 236 9.0E-7 T 13-10-2018 Spica_1559 e908e6abb8ac991b417e87dfd83a948e 247 SUPERFAMILY SSF51658 101 231 2.66E-6 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Spica_0108 082ca1a8e28bcb266e86c1b5c53133c9 131 SUPERFAMILY SSF88723 1 130 5.61E-35 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0108 082ca1a8e28bcb266e86c1b5c53133c9 131 Pfam PF01850 PIN domain 2 123 7.8E-17 T 13-10-2018 IPR002716 PIN domain Spica_0108 082ca1a8e28bcb266e86c1b5c53133c9 131 Gene3D G3DSA:3.40.50.1010 1 131 2.9E-38 T 13-10-2018 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 SMART SM01403 7 101 1.9E-57 T 13-10-2018 IPR027486 Ribosomal protein S10 domain Spica_0384 dbdee80c887956550f8d1520226edf8f 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.2E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.2E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.2E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 Gene3D G3DSA:3.30.70.600 1 102 8.1E-39 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Spica_0384 dbdee80c887956550f8d1520226edf8f 102 SUPERFAMILY SSF54999 5 101 6.93E-38 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Spica_0384 dbdee80c887956550f8d1520226edf8f 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 9.5E-37 T 13-10-2018 IPR027486 Ribosomal protein S10 domain Spica_0384 dbdee80c887956550f8d1520226edf8f 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.8E-46 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0384 dbdee80c887956550f8d1520226edf8f 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.848 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_2793 5f3bf8d8ec8ca101d392d0d04c681a42 379 Gene3D G3DSA:3.90.550.10 30 247 3.8E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2793 5f3bf8d8ec8ca101d392d0d04c681a42 379 Pfam PF00535 Glycosyl transferase family 2 46 216 1.2E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Spica_2793 5f3bf8d8ec8ca101d392d0d04c681a42 379 SUPERFAMILY SSF53448 32 298 2.25E-40 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0738 7bb50ddf834a3b99e192c542c939e93b 280 Gene3D G3DSA:1.10.3720.10 5 272 1.8E-49 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0738 7bb50ddf834a3b99e192c542c939e93b 280 SUPERFAMILY SSF161098 13 280 1.15E-57 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0738 7bb50ddf834a3b99e192c542c939e93b 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 275 1.2E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1993 1aa532fa79d5e45b8d41705cea9ec900 402 SUPERFAMILY SSF52540 5 206 3.43E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1993 1aa532fa79d5e45b8d41705cea9ec900 402 Pfam PF13635 Domain of unknown function (DUF4143) 203 349 3.6E-8 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_1993 1aa532fa79d5e45b8d41705cea9ec900 402 Pfam PF13173 AAA domain 21 152 2.3E-31 T 13-10-2018 Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 126 521 4.3E-66 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 SMART SM01008 7 107 1.3E-5 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 15 90 1.4E-6 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 SUPERFAMILY SSF56003 129 689 3.14E-89 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 SUPERFAMILY SSF54665 11 106 5.1E-14 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily Spica_1449 b967dc09f05bd36a23d1bef2b00ef82c 694 Gene3D G3DSA:3.30.365.10 10 690 7.7E-111 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 SUPERFAMILY SSF118215 20 428 4.84E-117 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 374 394 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 312 338 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 347 366 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 62 82 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 91 116 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 PRINTS PR00173 Glutamate-aspartate symporter signature 211 230 9.5E-55 T 13-10-2018 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 Pfam PF00375 Sodium:dicarboxylate symporter family 20 426 7.3E-123 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Spica_0580 a1bf1057b2fdbf280c619a82596af19a 437 Gene3D G3DSA:1.10.3860.10 8 437 4.7E-152 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Spica_1683 5a51e6141819a5c4547c1bb9f065d97d 273 Gene3D G3DSA:3.10.20.310 52 120 3.8E-6 T 13-10-2018 Spica_1683 5a51e6141819a5c4547c1bb9f065d97d 273 Pfam PF08478 POTRA domain, FtsQ-type 54 121 4.8E-13 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type Spica_2487 00ba0f7859a9c4079f351c1afe1d844f 446 Pfam PF02447 GntP family permease 7 442 1.7E-106 T 13-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spica_2487 00ba0f7859a9c4079f351c1afe1d844f 446 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 8 444 2.9E-92 T 13-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spica_2487 00ba0f7859a9c4079f351c1afe1d844f 446 PIRSF PIRSF002746 3 445 1.2E-124 T 13-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 SMART SM00729 242 464 6.1E-17 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 626 733 9.0E-27 T 13-10-2018 IPR018768 Domain of unknown function DUF2344 Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 Gene3D G3DSA:3.80.30.20 241 470 4.7E-16 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 Pfam PF04055 Radical SAM superfamily 246 397 3.6E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 626 725 7.8E-28 T 13-10-2018 IPR018768 Domain of unknown function DUF2344 Spica_1384 e86b8db23e95f0fe87320584c6e4e900 803 SUPERFAMILY SSF102114 246 553 2.88E-27 T 13-10-2018 Spica_2073 c33bfc2a3add70d12cf4300356a9edf1 298 Gene3D G3DSA:1.10.3720.10 53 291 4.5E-65 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2073 c33bfc2a3add70d12cf4300356a9edf1 298 SUPERFAMILY SSF161098 57 281 2.35E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2073 c33bfc2a3add70d12cf4300356a9edf1 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 287 1.2E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0889 9ae207c8617c735c772fbdf345a55317 375 Pfam PF13173 AAA domain 17 139 3.0E-24 T 13-10-2018 Spica_0889 9ae207c8617c735c772fbdf345a55317 375 SUPERFAMILY SSF52540 7 188 2.95E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0889 9ae207c8617c735c772fbdf345a55317 375 Gene3D G3DSA:3.40.50.300 4 76 1.3E-6 T 13-10-2018 Spica_0889 9ae207c8617c735c772fbdf345a55317 375 Pfam PF08279 HTH domain 201 245 1.5E-5 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Spica_0889 9ae207c8617c735c772fbdf345a55317 375 SMART SM00382 15 137 0.0027 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0889 9ae207c8617c735c772fbdf345a55317 375 Pfam PF13635 Domain of unknown function (DUF4143) 202 342 9.0E-19 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_0889 9ae207c8617c735c772fbdf345a55317 375 SUPERFAMILY SSF46785 196 262 1.0E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0349 dd80786636be39e5a2b291ec706bd4d2 132 Pfam PF02661 Fic/DOC family 7 88 4.2E-8 T 13-10-2018 IPR003812 Fido domain Spica_0349 dd80786636be39e5a2b291ec706bd4d2 132 Gene3D G3DSA:1.20.120.1870 4 132 7.4E-36 T 13-10-2018 Spica_0349 dd80786636be39e5a2b291ec706bd4d2 132 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 46 121 1.5E-15 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Spica_0349 dd80786636be39e5a2b291ec706bd4d2 132 PIRSF PIRSF018297 3 131 4.7E-37 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Spica_0291 df7896659788f526e27d3bc2f2d50497 798 SMART SM01068 1 63 8.7E-14 T 13-10-2018 IPR009342 Putative carbohydrate binding domain Spica_0291 df7896659788f526e27d3bc2f2d50497 798 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 295 725 3.5E-182 T 13-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain Spica_0291 df7896659788f526e27d3bc2f2d50497 798 Pfam PF06165 Glycosyltransferase family 36 21 265 2.3E-82 T 13-10-2018 IPR010383 Glycosyl hydrolase 94 Spica_0291 df7896659788f526e27d3bc2f2d50497 798 Gene3D G3DSA:1.50.10.10 310 719 1.1E-133 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_0291 df7896659788f526e27d3bc2f2d50497 798 Gene3D G3DSA:2.70.98.40 1 301 4.9E-99 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0291 df7896659788f526e27d3bc2f2d50497 798 SUPERFAMILY SSF48208 273 798 2.72E-106 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_0291 df7896659788f526e27d3bc2f2d50497 798 Gene3D G3DSA:2.60.420.10 720 798 2.1E-28 T 13-10-2018 Spica_0291 df7896659788f526e27d3bc2f2d50497 798 SUPERFAMILY SSF74650 1 267 1.82E-69 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 Pfam PF04542 Sigma-70 region 2 10 76 4.5E-14 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 SUPERFAMILY SSF88946 5 88 3.34E-17 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 159 9.2E-28 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 Gene3D G3DSA:1.10.10.10 104 166 3.5E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 Gene3D G3DSA:1.10.1740.10 2 103 4.6E-15 T 13-10-2018 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 Pfam PF08281 Sigma-70, region 4 106 158 3.8E-17 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Spica_0667 85e4c0dff8f6c52fec8da2a6ea721e7e 170 SUPERFAMILY SSF88659 100 162 1.08E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 SUPERFAMILY SSF53067 1 180 2.75E-64 T 13-10-2018 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Gene3D G3DSA:3.30.420.40 5 373 6.0E-161 T 13-10-2018 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 331 345 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Pfam PF00012 Hsp70 protein 4 598 9.7E-275 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 190 203 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 SUPERFAMILY SSF53067 185 376 3.02E-70 T 13-10-2018 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 382 401 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 135 155 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 54 62 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 196 206 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 359 379 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 328 344 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 463 479 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.3E-82 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Gene3D G3DSA:3.30.420.40 177 360 6.0E-161 T 13-10-2018 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 598 0.0 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 SUPERFAMILY SSF100920 378 534 1.18E-63 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 SUPERFAMILY SSF100934 501 601 9.68E-23 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Gene3D G3DSA:2.60.34.10 378 517 9.4E-66 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Gene3D G3DSA:3.90.640.10 223 310 6.0E-161 T 13-10-2018 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 631 38.712 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Spica_2740 fe7b4a2322115daba5c6980e7fc7a0f2 636 Gene3D G3DSA:1.20.1270.10 518 601 4.8E-28 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Spica_1038 e98e541d8ea49b83173f4d5f74be9a5e 147 SMART SM00712 6 73 7.2E-19 T 13-10-2018 IPR006628 Purine-rich element binding protein family Spica_1038 e98e541d8ea49b83173f4d5f74be9a5e 147 Pfam PF11680 Protein of unknown function (DUF3276) 5 115 1.6E-12 T 13-10-2018 IPR021694 Protein of unknown function DUF3276 Spica_1038 e98e541d8ea49b83173f4d5f74be9a5e 147 Gene3D G3DSA:3.10.450.700 1 78 1.8E-25 T 13-10-2018 Spica_0256 3c5a911e24fb75a31f295bc016a93a23 262 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 34 233 4.7E-20 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Spica_0256 3c5a911e24fb75a31f295bc016a93a23 262 Gene3D G3DSA:3.10.450.620 20 146 5.5E-6 T 13-10-2018 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 Gene3D G3DSA:1.25.40.10 15 215 1.8E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 Pfam PF13432 Tetratricopeptide repeat 101 148 1.6E-4 T 13-10-2018 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 Pfam PF07719 Tetratricopeptide repeat 166 198 3.2E-7 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 SUPERFAMILY SSF48452 34 201 1.33E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 SMART SM00028 166 199 1.1E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 SMART SM00028 132 165 13.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 SMART SM00028 61 94 67.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1150 f17ccc8a34e1d57aa9fab44f22cfe502 216 SMART SM00028 95 128 42.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1877 2d071693eb4c624f52613f18323beb45 92 SUPERFAMILY SSF55021 2 78 4.35E-22 T 13-10-2018 Spica_1877 2d071693eb4c624f52613f18323beb45 92 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 4 78 5.4E-30 T 13-10-2018 IPR023860 [FeFe]-hydrogenase system regulator TM1266 Spica_1877 2d071693eb4c624f52613f18323beb45 92 Gene3D G3DSA:3.30.70.1150 1 81 1.2E-30 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 SMART SM00382 87 240 3.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 SUPERFAMILY SSF52540 66 283 4.52E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 SUPERFAMILY SSF54211 250 429 1.14E-24 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 332 425 2.5E-7 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 Gene3D G3DSA:3.40.50.300 62 275 1.2E-38 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 3 427 4.3E-135 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 318 341 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 209 237 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 170 194 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 120 137 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 11 35 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 79 107 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 PRINTS PR01874 DNA repair protein radA signature 243 269 1.2E-77 T 13-10-2018 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 Gene3D G3DSA:3.30.230.10 289 456 1.7E-9 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 Hamap MF_01498 DNA repair protein RadA [radA]. 22 456 39.661 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Spica_2566 119e5a1582aed575456018f3eb47a5d3 457 Pfam PF13481 AAA domain 68 218 4.7E-10 T 13-10-2018 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 Pfam PF01926 50S ribosome-binding GTPase 162 277 2.6E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 PIRSF PIRSF002401 1 332 4.4E-127 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 SUPERFAMILY SSF52540 151 328 8.86E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 Gene3D G3DSA:2.70.210.12 1 159 7.9E-54 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.4E-29 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 1.4E-29 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 1.4E-29 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.4E-29 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 Pfam PF01018 GTP1/OBG 6 158 1.2E-56 T 13-10-2018 IPR006169 GTP1/OBG domain Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 325 1.0E-125 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 Gene3D G3DSA:3.40.50.300 160 332 3.5E-43 T 13-10-2018 Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 SUPERFAMILY SSF82051 3 158 4.45E-52 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily Spica_0785 9dbc5245372d234aec9f71a9d0f4a13e 332 Hamap MF_01454 GTPase Obg [obg]. 3 326 44.037 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Spica_1636 0c7ee5dfb63a2a57b08b2f3f560f6c03 317 SUPERFAMILY SSF53448 69 262 1.69E-8 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 Pfam PF00295 Glycosyl hydrolases family 28 164 342 5.1E-39 T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SMART SM00710 223 255 17.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SMART SM00710 257 278 56.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SMART SM00710 196 222 160.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SMART SM00710 362 384 6500.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SMART SM00710 284 305 220.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 Gene3D G3DSA:2.160.20.10 12 434 3.5E-111 T 13-10-2018 IPR012334 Pectin lyase fold Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 SUPERFAMILY SSF51126 15 399 5.47E-82 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_0634 c2920c6ab4338574ce5fa0734a780768 467 ProSitePatterns PS00502 Polygalacturonase active site. 264 278 - T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Spica_2072 54516935e0482762d2a7f16acdfd3f82 293 SUPERFAMILY SSF161098 26 293 3.18E-63 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2072 54516935e0482762d2a7f16acdfd3f82 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 282 3.5E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2072 54516935e0482762d2a7f16acdfd3f82 293 Gene3D G3DSA:1.10.3720.10 22 279 2.8E-54 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 SUPERFAMILY SSF52313 6 226 2.22E-94 T 13-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.3E-112 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 Pfam PF00318 Ribosomal protein S2 9 224 6.7E-98 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.2E-39 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 Gene3D G3DSA:1.10.287.610 103 150 3.8E-92 T 13-10-2018 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 Gene3D G3DSA:3.40.50.10490 9 219 3.8E-92 T 13-10-2018 Spica_1415 157a2d4ac622667e6a1739bbb5f7d7b7 294 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 230 42.857 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0991 88d4abaae2d647bf636b902dbc3acd19 114 SUPERFAMILY SSF51182 16 110 2.76E-26 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0991 88d4abaae2d647bf636b902dbc3acd19 114 Gene3D G3DSA:2.60.120.10 1 113 3.5E-32 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0991 88d4abaae2d647bf636b902dbc3acd19 114 Pfam PF07883 Cupin domain 39 106 4.9E-20 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_0534 dfe37145b5181dcc9a19aeb1a8eb10c9 111 Gene3D G3DSA:3.30.2310.20 1 102 1.4E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_0534 dfe37145b5181dcc9a19aeb1a8eb10c9 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 98 8.9E-12 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_1141 5b00da217bca61a6099d2106f08210ab 188 Gene3D G3DSA:3.40.50.410 18 187 2.2E-9 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1141 5b00da217bca61a6099d2106f08210ab 188 Pfam PF00092 von Willebrand factor type A domain 20 138 3.4E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_1141 5b00da217bca61a6099d2106f08210ab 188 SUPERFAMILY SSF53300 16 135 8.73E-12 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_0588 205a3cdcaad925122ed38d025633f4a7 311 SUPERFAMILY SSF81345 35 307 1.57E-60 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_0588 205a3cdcaad925122ed38d025633f4a7 311 Pfam PF01032 FecCD transport family 47 179 1.1E-29 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Spica_0588 205a3cdcaad925122ed38d025633f4a7 311 Pfam PF01032 FecCD transport family 180 307 8.5E-35 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Spica_0588 205a3cdcaad925122ed38d025633f4a7 311 Gene3D G3DSA:1.10.3470.10 181 310 1.9E-39 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_0588 205a3cdcaad925122ed38d025633f4a7 311 Gene3D G3DSA:1.10.3470.10 23 180 2.5E-36 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Spica_0008 2556e004325921d800170493ff92a56b 228 SMART SM01245 4 53 8.5E-11 T 13-10-2018 IPR032782 Jag, N-terminal Spica_0008 2556e004325921d800170493ff92a56b 228 Pfam PF14804 Jag N-terminus 5 50 7.5E-11 T 13-10-2018 IPR032782 Jag, N-terminal Spica_0008 2556e004325921d800170493ff92a56b 228 SMART SM00393 145 224 3.9E-23 T 13-10-2018 IPR001374 R3H domain GO:0003676 Spica_0008 2556e004325921d800170493ff92a56b 228 Gene3D G3DSA:3.30.300.20 77 159 1.1E-21 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_0008 2556e004325921d800170493ff92a56b 228 Gene3D G3DSA:3.30.30.80 2 48 3.4E-6 T 13-10-2018 IPR038247 Jag, N-terminal domain superfamily Spica_0008 2556e004325921d800170493ff92a56b 228 Pfam PF13083 KH domain 85 144 1.8E-11 T 13-10-2018 Spica_0008 2556e004325921d800170493ff92a56b 228 Pfam PF01424 R3H domain 165 222 9.9E-12 T 13-10-2018 IPR001374 R3H domain GO:0003676 Spica_0008 2556e004325921d800170493ff92a56b 228 Gene3D G3DSA:3.30.1370.50 160 228 7.6E-23 T 13-10-2018 IPR036867 R3H domain superfamily GO:0003676 Spica_0008 2556e004325921d800170493ff92a56b 228 SUPERFAMILY SSF82708 172 223 3.14E-7 T 13-10-2018 IPR036867 R3H domain superfamily GO:0003676 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 SMART SM00448 6 120 1.7E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 SUPERFAMILY SSF46689 492 540 5.82E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 SMART SM00342 455 538 5.3E-25 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 SUPERFAMILY SSF52172 9 156 4.98E-32 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 Pfam PF00072 Response regulator receiver domain 9 120 4.5E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 Gene3D G3DSA:1.10.10.2730 493 539 2.7E-20 T 13-10-2018 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 507 522 5.1E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 522 538 5.1E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 Gene3D G3DSA:3.40.50.2300 7 146 3.1E-30 T 13-10-2018 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 Pfam PF12833 Helix-turn-helix domain 461 539 2.1E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2146 7c4a7a0dc1ed48d0bcdf0ce07b626939 542 Gene3D G3DSA:1.10.10.60 439 492 3.3E-13 T 13-10-2018 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 Gene3D G3DSA:3.20.20.210 389 751 1.4E-284 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 3 324 5.2E-94 T 13-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 Gene3D G3DSA:3.20.20.210 5 519 1.4E-284 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 426 748 8.2E-131 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 PIRSF PIRSF000382 1 755 6.1E-278 T 13-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 SUPERFAMILY SSF51726 403 752 2.22E-102 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Spica_1013 826c2886ca69f03bfc9948344ab84d1d 755 SUPERFAMILY SSF51726 1 378 7.19E-78 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Spica_0917 f90e150581151f3b41d845be560082c8 223 Gene3D G3DSA:3.20.20.70 1 223 2.9E-103 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0917 f90e150581151f3b41d845be560082c8 223 SMART SM01133 9 220 1.8E-106 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Spica_0917 f90e150581151f3b41d845be560082c8 223 SUPERFAMILY SSF51569 5 221 3.77E-89 T 13-10-2018 Spica_0917 f90e150581151f3b41d845be560082c8 223 Pfam PF01791 DeoC/LacD family aldolase 10 217 3.8E-21 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Spica_0917 f90e150581151f3b41d845be560082c8 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 8 222 36.875 T 13-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 Spica_0917 f90e150581151f3b41d845be560082c8 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 10 218 1.2E-85 T 13-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Spica_0917 f90e150581151f3b41d845be560082c8 223 PIRSF PIRSF001357 3 222 4.6E-84 T 13-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 Gene3D G3DSA:3.20.20.140 62 351 2.0E-117 T 13-10-2018 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 SUPERFAMILY SSF51556 61 353 1.57E-82 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 SUPERFAMILY SSF51338 4 384 5.55E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 Pfam PF01979 Amidohydrolase family 57 383 3.5E-36 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 PIRSF PIRSF038994 3 387 1.3E-120 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 382 1.1E-128 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 Spica_2472 ad2b169a34da7318bcf46c5581c29bef 389 Gene3D G3DSA:2.30.40.10 10 382 2.0E-117 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Gene3D G3DSA:1.20.120.1080 387 490 5.9E-15 T 13-10-2018 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 558 624 1.8E-8 T 13-10-2018 IPR011709 Domain of unknown function DUF1605 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Gene3D G3DSA:3.40.50.300 182 362 3.3E-55 T 13-10-2018 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Pfam PF00271 Helicase conserved C-terminal domain 215 344 2.2E-15 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Pfam PF04408 Helicase associated domain (HA2) 406 501 1.2E-13 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 SMART SM00487 4 188 2.0E-26 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 SMART SM00490 243 345 2.5E-17 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Pfam PF00270 DEAD/DEAH box helicase 17 164 7.8E-7 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 Gene3D G3DSA:3.40.50.300 2 180 2.1E-73 T 13-10-2018 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 SMART SM00847 405 497 3.0E-22 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Spica_1303 ce89d7d7a8c0cd501fa6b715ff79fbba 833 SUPERFAMILY SSF52540 7 520 1.64E-83 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1402 08ef8288e6117cfd6d36d67abf1497d7 216 SUPERFAMILY SSF63862 144 199 1.44E-6 T 13-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Spica_1402 08ef8288e6117cfd6d36d67abf1497d7 216 SUPERFAMILY SSF63999 4 119 5.89E-26 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Spica_1402 08ef8288e6117cfd6d36d67abf1497d7 216 Gene3D G3DSA:3.40.50.10240 7 212 3.5E-40 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Spica_1402 08ef8288e6117cfd6d36d67abf1497d7 216 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 8 206 6.2E-32 T 13-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Spica_1402 08ef8288e6117cfd6d36d67abf1497d7 216 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 24 115 1.2E-15 T 13-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 Spica_2121 1f0c39cd232bdc2976d9ea5ed307bbdf 306 Gene3D G3DSA:1.10.3720.10 52 304 2.2E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2121 1f0c39cd232bdc2976d9ea5ed307bbdf 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 302 2.7E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2121 1f0c39cd232bdc2976d9ea5ed307bbdf 306 SUPERFAMILY SSF161098 56 294 4.45E-46 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2451 09e978df805a01c22659f7088cb2427a 472 PIRSF PIRSF006603 13 472 1.4E-62 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2451 09e978df805a01c22659f7088cb2427a 472 Pfam PF01554 MatE 38 187 7.2E-13 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2451 09e978df805a01c22659f7088cb2427a 472 Pfam PF01554 MatE 260 419 4.3E-19 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_1070 829e394097c60ddf9655a41f35698849 428 Gene3D G3DSA:2.30.30.40 261 323 5.6E-5 T 13-10-2018 Spica_1070 829e394097c60ddf9655a41f35698849 428 Pfam PF08239 Bacterial SH3 domain 266 323 1.4E-6 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type Spica_2420 fbb72300bff0d895c399414d9e276795 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 289 1.6E-10 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2420 fbb72300bff0d895c399414d9e276795 299 Gene3D G3DSA:1.10.3720.10 3 289 1.1E-66 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2420 fbb72300bff0d895c399414d9e276795 299 SUPERFAMILY SSF161098 11 298 2.78E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2572 ad332138c4d6a79de971ea9d02d8dbbe 629 SUPERFAMILY SSF51445 5 478 1.98E-47 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2572 ad332138c4d6a79de971ea9d02d8dbbe 629 Gene3D G3DSA:2.60.40.1180 522 628 5.7E-10 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2572 ad332138c4d6a79de971ea9d02d8dbbe 629 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 53 238 1.8E-13 T 13-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 SUPERFAMILY SSF82866 681 879 2.88E-36 T 13-10-2018 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 SUPERFAMILY SSF82866 172 372 6.15E-31 T 13-10-2018 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 Pfam PF03176 MMPL family 667 876 1.5E-21 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 Pfam PF03176 MMPL family 139 373 1.4E-22 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 Gene3D G3DSA:1.20.1640.10 204 388 2.7E-13 T 13-10-2018 Spica_0288 7eeaf9f9923ac9f411c6998eac907483 885 Gene3D G3DSA:1.20.1640.10 697 882 8.9E-15 T 13-10-2018 Spica_1741 a02f6f67b3b53dddee77f0ce7d92c988 139 Gene3D G3DSA:3.40.50.1010 4 138 1.7E-26 T 13-10-2018 Spica_1741 a02f6f67b3b53dddee77f0ce7d92c988 139 SUPERFAMILY SSF88723 1 130 7.29E-22 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1741 a02f6f67b3b53dddee77f0ce7d92c988 139 Pfam PF01850 PIN domain 5 122 1.3E-9 T 13-10-2018 IPR002716 PIN domain Spica_1736 a02f6f67b3b53dddee77f0ce7d92c988 139 Gene3D G3DSA:3.40.50.1010 4 138 1.7E-26 T 13-10-2018 Spica_1736 a02f6f67b3b53dddee77f0ce7d92c988 139 SUPERFAMILY SSF88723 1 130 7.29E-22 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1736 a02f6f67b3b53dddee77f0ce7d92c988 139 Pfam PF01850 PIN domain 5 122 1.3E-9 T 13-10-2018 IPR002716 PIN domain Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 Gene3D G3DSA:3.40.50.720 1 251 2.7E-84 T 13-10-2018 Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 Gene3D G3DSA:2.60.120.10 254 370 2.8E-31 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 SUPERFAMILY SSF51182 254 366 4.65E-19 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 178 2.7E-15 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 285 358 2.1E-5 T 13-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 Spica_0525 2bc07d10e698e6caff03799a67f6ca42 370 SUPERFAMILY SSF51735 1 218 8.93E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0623 7775c991d3b617f835125c918e0a377a 806 Pfam PF13802 Galactose mutarotase-like 149 210 4.3E-17 T 13-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain Spica_0623 7775c991d3b617f835125c918e0a377a 806 SUPERFAMILY SSF74650 5 242 2.67E-25 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_0623 7775c991d3b617f835125c918e0a377a 806 Gene3D G3DSA:2.60.40.1180 592 668 1.2E-6 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_0623 7775c991d3b617f835125c918e0a377a 806 SUPERFAMILY SSF51011 588 668 7.19E-7 T 13-10-2018 Spica_0623 7775c991d3b617f835125c918e0a377a 806 Gene3D G3DSA:2.60.40.1760 7 237 6.7E-28 T 13-10-2018 Spica_0623 7775c991d3b617f835125c918e0a377a 806 Gene3D G3DSA:3.20.20.80 245 591 4.9E-94 T 13-10-2018 Spica_0623 7775c991d3b617f835125c918e0a377a 806 Pfam PF01055 Glycosyl hydrolases family 31 238 673 4.6E-100 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Spica_0623 7775c991d3b617f835125c918e0a377a 806 SUPERFAMILY SSF51445 247 586 1.66E-68 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 Gene3D G3DSA:1.10.10.10 1 79 8.4E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 210 29.25 T 13-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 SUPERFAMILY SSF51735 85 206 1.71E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 7.6E-16 T 13-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 SUPERFAMILY SSF46785 10 80 3.81E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 Gene3D G3DSA:3.40.50.720 80 214 3.6E-42 T 13-10-2018 Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 SMART SM00881 80 181 8.0E-13 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Spica_1600 5e325d4e55eb335405559907c4d2b0f3 214 Pfam PF02629 CoA binding domain 86 179 5.0E-20 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Spica_0969 344dd249379ec7e64176700837aef978 75 Gene3D G3DSA:3.30.110.40 1 73 1.4E-23 T 13-10-2018 IPR036868 TusA-like domain superfamily Spica_0969 344dd249379ec7e64176700837aef978 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 13-10-2018 IPR001455 TusA-like domain Spica_0969 344dd249379ec7e64176700837aef978 75 Pfam PF01206 Sulfurtransferase TusA 5 73 7.2E-24 T 13-10-2018 IPR001455 TusA-like domain Spica_0969 344dd249379ec7e64176700837aef978 75 SUPERFAMILY SSF64307 4 73 1.96E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily Spica_1356 ca68ac8ba7889ec65c163ef8f9a8d7bb 306 Gene3D G3DSA:3.30.2350.10 2 240 3.4E-79 T 13-10-2018 Spica_1356 ca68ac8ba7889ec65c163ef8f9a8d7bb 306 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 304 16.296 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1356 ca68ac8ba7889ec65c163ef8f9a8d7bb 306 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 9 210 9.7E-74 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1356 ca68ac8ba7889ec65c163ef8f9a8d7bb 306 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 30 176 1.4E-47 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Spica_1356 ca68ac8ba7889ec65c163ef8f9a8d7bb 306 SUPERFAMILY SSF55120 9 216 5.96E-66 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_0754 ebf9e25e3a6df25399b4a29ac906c088 376 TIGRFAM TIGR00238 TIGR00238: KamA family protein 21 334 4.0E-69 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Spica_0754 ebf9e25e3a6df25399b4a29ac906c088 376 Pfam PF13353 4Fe-4S single cluster domain 119 194 3.1E-5 T 13-10-2018 Spica_0754 ebf9e25e3a6df25399b4a29ac906c088 376 Pfam PF04055 Radical SAM superfamily 125 272 5.9E-7 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_0754 ebf9e25e3a6df25399b4a29ac906c088 376 SUPERFAMILY SSF102114 110 347 2.09E-27 T 13-10-2018 Spica_0754 ebf9e25e3a6df25399b4a29ac906c088 376 Gene3D G3DSA:3.20.20.70 60 340 1.8E-85 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 PIRSF PIRSF006444 1 433 2.5E-196 T 13-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 SUPERFAMILY SSF56801 44 400 3.92E-52 T 13-10-2018 Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 Gene3D G3DSA:3.30.300.30 326 433 1.9E-32 T 13-10-2018 Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 Gene3D G3DSA:3.40.50.12780 2 325 4.5E-125 T 13-10-2018 Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 431 2.5E-30 T 13-10-2018 IPR028154 AMP-dependent ligase, C-terminal Spica_1264 32c26faeb6fd546cec8b02dc7c8f5d3d 433 Pfam PF00501 AMP-binding enzyme 90 284 2.5E-12 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:3.90.1100.10 17 157 8.1E-48 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:3.90.1100.10 608 676 1.9E-20 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:2.40.270.10 982 1048 3.2E-18 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF04560 RNA polymerase Rpb2, domain 7 1072 1146 1.1E-24 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 SUPERFAMILY SSF64484 18 1153 0.0 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:3.90.1100.10 361 592 3.9E-74 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF10385 RNA polymerase beta subunit external 1 domain 554 619 1.1E-23 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:3.90.1110.10 158 279 4.7E-21 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 15 897 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF04565 RNA polymerase Rpb2, domain 3 476 544 1.5E-29 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 ProSitePatterns PS01166 RNA polymerases beta chain signature. 923 935 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF04563 RNA polymerase beta subunit 26 461 1.1E-26 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:2.40.50.100 677 755 2.3E-27 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 10 1148 12.183 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:2.40.50.150 787 931 1.4E-57 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF00562 RNA polymerase Rpb2, domain 6 681 1070 9.1E-158 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Gene3D G3DSA:3.90.1800.10 1058 1111 5.3E-10 T 13-10-2018 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 238 1.1E-4 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0379 df765dc0947762b19dae009efaaf79fa 1170 Pfam PF04561 RNA polymerase Rpb2, domain 2 314 417 2.3E-20 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Spica_0411 2d0c80f7db04fc8941a5efc074d6bcf4 154 Pfam PF01196 Ribosomal protein L17 20 116 1.0E-33 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0411 2d0c80f7db04fc8941a5efc074d6bcf4 154 SUPERFAMILY SSF64263 1 119 1.96E-43 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0411 2d0c80f7db04fc8941a5efc074d6bcf4 154 Gene3D G3DSA:3.90.1030.10 1 116 8.2E-43 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0411 2d0c80f7db04fc8941a5efc074d6bcf4 154 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.786 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0411 2d0c80f7db04fc8941a5efc074d6bcf4 154 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.2E-42 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0172 cfe9fec022dc96738a9f82d549a5c9f5 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 206 25.402 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0172 cfe9fec022dc96738a9f82d549a5c9f5 211 SUPERFAMILY SSF51391 3 206 2.49E-60 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0172 cfe9fec022dc96738a9f82d549a5c9f5 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 8 200 3.6E-58 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0172 cfe9fec022dc96738a9f82d549a5c9f5 211 Pfam PF02581 Thiamine monophosphate synthase 8 188 1.8E-54 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0172 cfe9fec022dc96738a9f82d549a5c9f5 211 Gene3D G3DSA:3.20.20.70 4 208 5.4E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0974 973f153a6f5d00d0179c1d4f5b0b6b40 310 Gene3D G3DSA:2.60.40.1820 167 308 3.7E-17 T 13-10-2018 Spica_0974 973f153a6f5d00d0179c1d4f5b0b6b40 310 SMART SM00769 185 303 1.9E-5 T 13-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 Spica_0974 973f153a6f5d00d0179c1d4f5b0b6b40 310 SUPERFAMILY SSF117070 179 301 1.14E-19 T 13-10-2018 Spica_0974 973f153a6f5d00d0179c1d4f5b0b6b40 310 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 182 308 1.0E-4 T 13-10-2018 Spica_2605 307746d56ec6477e2e2d7e09bf8c2876 304 SUPERFAMILY SSF52540 3 226 1.04E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2605 307746d56ec6477e2e2d7e09bf8c2876 304 Pfam PF00005 ABC transporter 21 164 1.3E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2605 307746d56ec6477e2e2d7e09bf8c2876 304 Gene3D G3DSA:3.40.50.300 1 236 3.3E-74 T 13-10-2018 Spica_2605 307746d56ec6477e2e2d7e09bf8c2876 304 SMART SM00382 29 214 8.5E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2605 307746d56ec6477e2e2d7e09bf8c2876 304 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2755 aeded8cc9581cd056116275116a44900 255 SMART SM00382 29 218 5.8E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2755 aeded8cc9581cd056116275116a44900 255 Gene3D G3DSA:3.40.50.300 2 250 4.7E-60 T 13-10-2018 Spica_2755 aeded8cc9581cd056116275116a44900 255 SUPERFAMILY SSF52540 4 228 1.6E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2755 aeded8cc9581cd056116275116a44900 255 Pfam PF00005 ABC transporter 20 170 1.8E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0119 77432dcf4dd086f666e4d654c550ea42 159 Pfam PF03928 Haem-degrading 23 150 3.4E-32 T 13-10-2018 IPR005624 Haem-degrading Spica_0119 77432dcf4dd086f666e4d654c550ea42 159 Hamap MF_00761 UPF0303 protein . 1 156 32.747 T 13-10-2018 IPR010371 Uncharacterised protein family UPF0303 Spica_0119 77432dcf4dd086f666e4d654c550ea42 159 SUPERFAMILY SSF143744 15 153 9.15E-25 T 13-10-2018 IPR038084 GlcG-like domain superfamily Spica_0119 77432dcf4dd086f666e4d654c550ea42 159 PIRSF PIRSF008757 1 158 1.1E-60 T 13-10-2018 IPR010371 Uncharacterised protein family UPF0303 Spica_0119 77432dcf4dd086f666e4d654c550ea42 159 Gene3D G3DSA:3.30.450.150 1 158 2.0E-56 T 13-10-2018 IPR038084 GlcG-like domain superfamily Spica_1065 644b3707194f182964ffaae8884701b9 1034 SUPERFAMILY SSF82714 722 807 3.4E-9 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.70.1320 135 324 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.0E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.70.1430 41 820 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.70.1430 566 676 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:1.20.1640.10 503 1013 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.2090.10 724 812 3.5E-200 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1065 644b3707194f182964ffaae8884701b9 1034 Pfam PF00873 AcrB/AcrD/AcrF family 7 1016 3.8E-159 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:1.20.1640.10 11 502 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 SUPERFAMILY SSF82866 290 487 3.79E-30 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 SUPERFAMILY SSF82693 42 135 2.88E-20 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.2090.10 180 271 3.5E-200 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1065 644b3707194f182964ffaae8884701b9 1034 SUPERFAMILY SSF82866 809 1019 4.58E-30 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 Gene3D G3DSA:3.30.70.1440 677 865 3.5E-200 T 13-10-2018 Spica_1065 644b3707194f182964ffaae8884701b9 1034 SUPERFAMILY SSF82693 137 323 9.68E-15 T 13-10-2018 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 275 27.041 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 SUPERFAMILY SSF51735 4 166 4.54E-25 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 PIRSF PIRSF000193 2 276 6.4E-73 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 103 5.0E-12 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 Gene3D G3DSA:1.10.3730.10 174 276 4.8E-42 T 13-10-2018 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 SUPERFAMILY SSF48179 170 276 1.38E-37 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 171 275 5.4E-41 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 231 253 - T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 275 2.2E-80 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Spica_0842 be0e74f1213bc2d274c96badc24008c7 276 Gene3D G3DSA:3.40.50.720 1 173 2.7E-37 T 13-10-2018 Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 Pfam PF00271 Helicase conserved C-terminal domain 299 403 6.4E-16 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 212 221 - T 13-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 Pfam PF00270 DEAD/DEAH box helicase 113 260 1.3E-10 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 114 433 4.4E-78 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 SUPERFAMILY SSF52540 137 418 6.93E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 Gene3D G3DSA:3.40.50.300 105 274 9.3E-47 T 13-10-2018 Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 SMART SM00490 321 404 1.1E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1954 89dc189c4cf441057f56fca0b83dd5e8 574 SMART SM00487 37 288 3.4E-21 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1092 11355ae4830d00c458cdf6e3e1975bb0 182 Pfam PF13581 Histidine kinase-like ATPase domain 44 114 1.2E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1092 11355ae4830d00c458cdf6e3e1975bb0 182 SUPERFAMILY SSF55874 44 108 7.2E-9 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1092 11355ae4830d00c458cdf6e3e1975bb0 182 Gene3D G3DSA:3.30.565.10 19 145 1.3E-9 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 SUPERFAMILY SSF50193 1 122 1.11E-52 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.6E-59 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 SMART SM01374 1 122 2.7E-87 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 5.5E-56 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 Gene3D G3DSA:2.40.150.20 1 122 2.9E-55 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0395 09d6c65b44d560a547fc2e03c8410663 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.342 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Spica_0793 791b311a8074b78aacd552153bbc93b6 500 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 28 215 7.3E-49 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spica_0793 791b311a8074b78aacd552153bbc93b6 500 Gene3D G3DSA:3.40.50.620 6 220 1.0E-59 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0793 791b311a8074b78aacd552153bbc93b6 500 Pfam PF01171 PP-loop family 28 211 5.1E-48 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Spica_0793 791b311a8074b78aacd552153bbc93b6 500 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 16 307 21.786 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 Spica_0793 791b311a8074b78aacd552153bbc93b6 500 SUPERFAMILY SSF52402 17 229 5.29E-48 T 13-10-2018 Spica_0866 5308fbcd317961a8ff345c2407d01ca3 92 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 2.1E-12 T 13-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 Spica_1523 f33d9e8b066b17a1378e03181888d76e 296 Pfam PF13614 AAA domain 33 201 1.1E-18 T 13-10-2018 IPR025669 AAA domain Spica_1523 f33d9e8b066b17a1378e03181888d76e 296 PIRSF PIRSF003092 1 296 1.3E-85 T 13-10-2018 IPR025501 ATP binding protein MinD Spica_1523 f33d9e8b066b17a1378e03181888d76e 296 SUPERFAMILY SSF52540 32 277 1.85E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1523 f33d9e8b066b17a1378e03181888d76e 296 Gene3D G3DSA:3.40.50.300 33 274 2.4E-55 T 13-10-2018 Spica_2705 714a59a736e9be3e0354278a41991020 650 SUPERFAMILY SSF55874 233 369 5.37E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2705 714a59a736e9be3e0354278a41991020 650 Pfam PF00583 Acetyltransferase (GNAT) family 39 125 4.1E-8 T 13-10-2018 IPR000182 GNAT domain Spica_2705 714a59a736e9be3e0354278a41991020 650 Gene3D G3DSA:3.30.565.10 215 368 9.4E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2705 714a59a736e9be3e0354278a41991020 650 SUPERFAMILY SSF55729 26 132 1.49E-11 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2705 714a59a736e9be3e0354278a41991020 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 369 2.8E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2705 714a59a736e9be3e0354278a41991020 650 Gene3D G3DSA:3.40.630.30 17 136 9.8E-12 T 13-10-2018 Spica_2705 714a59a736e9be3e0354278a41991020 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 312 4.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2705 714a59a736e9be3e0354278a41991020 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 368 4.1E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2705 714a59a736e9be3e0354278a41991020 650 Gene3D G3DSA:1.10.287.130 188 214 9.4E-15 T 13-10-2018 Spica_0996 32077bc36b8b65a52a3053aef755dd88 263 SUPERFAMILY SSF54862 5 65 6.91E-16 T 13-10-2018 Spica_0996 32077bc36b8b65a52a3053aef755dd88 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0996 32077bc36b8b65a52a3053aef755dd88 263 Pfam PF12837 4Fe-4S binding domain 5 28 1.5E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0996 32077bc36b8b65a52a3053aef755dd88 263 Gene3D G3DSA:3.30.70.20 2 69 2.6E-11 T 13-10-2018 Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 Gene3D G3DSA:3.50.50.60 26 373 3.1E-116 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 Gene3D G3DSA:1.10.10.1100 412 484 2.1E-22 T 13-10-2018 Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 SUPERFAMILY SSF51905 24 431 3.88E-45 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 Gene3D G3DSA:3.30.9.10 109 339 3.1E-116 T 13-10-2018 Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 Pfam PF04324 BFD-like [2Fe-2S] binding domain 423 473 1.2E-13 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 Pfam PF01266 FAD dependent oxidoreductase 26 377 1.2E-67 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spica_2723 d7b213484fe45fd9fdcce9fc8e07fdfc 498 SUPERFAMILY SSF54373 246 338 7.06E-11 T 13-10-2018 Spica_0571 078345d1af1622ab35c8b2127be41108 545 SUPERFAMILY SSF52540 2 238 1.8E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0571 078345d1af1622ab35c8b2127be41108 545 SUPERFAMILY SSF52540 317 405 2.27E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0571 078345d1af1622ab35c8b2127be41108 545 Gene3D G3DSA:3.40.50.300 283 544 1.0E-39 T 13-10-2018 Spica_0571 078345d1af1622ab35c8b2127be41108 545 Pfam PF00005 ABC transporter 18 184 1.8E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0571 078345d1af1622ab35c8b2127be41108 545 Pfam PF00005 ABC transporter 335 466 1.2E-10 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0571 078345d1af1622ab35c8b2127be41108 545 Pfam PF12848 ABC transporter 224 298 1.1E-19 T 13-10-2018 IPR032781 ABC-transporter extension domain Spica_0571 078345d1af1622ab35c8b2127be41108 545 SUPERFAMILY SSF52540 214 511 3.87E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0571 078345d1af1622ab35c8b2127be41108 545 Gene3D G3DSA:3.40.50.300 3 281 8.7E-61 T 13-10-2018 Spica_0571 078345d1af1622ab35c8b2127be41108 545 SMART SM00382 344 511 0.21 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0571 078345d1af1622ab35c8b2127be41108 545 SMART SM00382 26 231 1.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 Pfam PF00364 Biotin-requiring enzyme 525 590 7.4E-13 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 SUPERFAMILY SSF51230 518 590 7.2E-17 T 13-10-2018 IPR011053 Single hybrid motif Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 Gene3D G3DSA:2.40.50.100 523 591 2.1E-19 T 13-10-2018 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 Pfam PF02436 Conserved carboxylase domain 291 490 1.9E-53 T 13-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 Gene3D G3DSA:3.20.20.70 1 454 2.2E-168 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 Pfam PF00682 HMGL-like 3 269 1.4E-49 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 SUPERFAMILY SSF51569 2 298 7.87E-88 T 13-10-2018 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 SUPERFAMILY SSF89000 296 454 9.81E-49 T 13-10-2018 Spica_1031 24b11ea2b6930a485f69e98323e1fa32 591 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 585 9.1E-248 T 13-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 489 1.8E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 Gene3D G3DSA:1.20.1480.50 164 263 9.3E-7 T 13-10-2018 Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 Pfam PF06580 Histidine kinase 286 363 1.4E-19 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 SUPERFAMILY SSF158472 205 255 1.7E-5 T 13-10-2018 Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 Gene3D G3DSA:3.30.565.10 359 493 1.3E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0032 e25f040d03c1d4dc6f8bf009fc025094 496 SUPERFAMILY SSF55874 340 486 5.76E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 67 263 8.6E-25 T 13-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 Gene3D G3DSA:3.40.50.2300 167 298 2.9E-53 T 13-10-2018 Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 Gene3D G3DSA:3.40.50.2300 68 316 2.9E-53 T 13-10-2018 Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 SUPERFAMILY SSF53822 66 317 7.5E-47 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 SMART SM00354 6 78 2.9E-22 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 Gene3D G3DSA:1.10.260.40 1 66 2.2E-18 T 13-10-2018 Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 55 1.0E-12 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2243 fb58b4029d91cfb4a1ab88e25ced4aa0 351 SUPERFAMILY SSF47413 6 66 1.13E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0220 14ad7345e8f0c81b12015cfa32e206db 87 SUPERFAMILY SSF52833 7 83 3.24E-8 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0220 14ad7345e8f0c81b12015cfa32e206db 87 Gene3D G3DSA:3.40.30.10 3 82 2.2E-12 T 13-10-2018 Spica_0220 14ad7345e8f0c81b12015cfa32e206db 87 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 7 76 1.3E-5 T 13-10-2018 Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 75 310 7.4E-39 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 SUPERFAMILY SSF55785 421 524 1.31E-5 T 13-10-2018 IPR035965 PAS domain superfamily Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Pfam PF13188 PAS domain 423 457 9.9E-6 T 13-10-2018 IPR000014 PAS domain Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Pfam PF00037 4Fe-4S binding domain 38 57 2.7E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Pfam PF04060 Putative Fe-S cluster 383 411 1.1E-10 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Gene3D G3DSA:3.20.20.20 374 440 5.2E-8 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 SUPERFAMILY SSF54862 11 84 1.13E-16 T 13-10-2018 Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 Gene3D G3DSA:3.30.70.20 3 65 2.9E-12 T 13-10-2018 Spica_0218 e449b13bdd293a286f3530ca595a2ef4 580 SUPERFAMILY SSF53920 43 333 7.46E-50 T 13-10-2018 IPR009016 Iron hydrogenase Spica_0019 8a801bd34992266912584bc599c01acf 287 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 93 264 8.6E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0019 8a801bd34992266912584bc599c01acf 287 SMART SM00283 31 285 1.7E-7 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0019 8a801bd34992266912584bc599c01acf 287 Gene3D G3DSA:1.10.287.950 2 283 1.4E-42 T 13-10-2018 Spica_0019 8a801bd34992266912584bc599c01acf 287 SUPERFAMILY SSF58104 41 277 5.49E-44 T 13-10-2018 Spica_1201 4996dccfc80662292bff768bf5168e94 274 PIRSF PIRSF004793 5 261 3.0E-83 T 13-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 Spica_1201 4996dccfc80662292bff768bf5168e94 274 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 8 247 5.1E-69 T 13-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 Spica_1201 4996dccfc80662292bff768bf5168e94 274 SUPERFAMILY SSF143597 42 237 4.32E-58 T 13-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Spica_1201 4996dccfc80662292bff768bf5168e94 274 Gene3D G3DSA:3.40.1700.10 101 252 1.2E-52 T 13-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Spica_1201 4996dccfc80662292bff768bf5168e94 274 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 116 233 2.2E-40 T 13-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal Spica_1201 4996dccfc80662292bff768bf5168e94 274 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 252 30.172 T 13-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 Spica_1909 c09061adfdb6dab0163c7b4e6d008658 443 Gene3D G3DSA:3.40.190.10 154 426 1.7E-86 T 13-10-2018 Spica_1909 c09061adfdb6dab0163c7b4e6d008658 443 SUPERFAMILY SSF53850 37 431 4.3E-72 T 13-10-2018 Spica_1909 c09061adfdb6dab0163c7b4e6d008658 443 Pfam PF13416 Bacterial extracellular solute-binding protein 54 378 8.7E-39 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1909 c09061adfdb6dab0163c7b4e6d008658 443 Gene3D G3DSA:3.40.190.10 52 398 1.7E-86 T 13-10-2018 Spica_1713 f56c56134b248613eacdd50962b5f4f9 286 SUPERFAMILY SSF161098 25 268 5.14E-33 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1713 f56c56134b248613eacdd50962b5f4f9 286 Gene3D G3DSA:1.10.3720.10 66 284 1.2E-29 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1713 f56c56134b248613eacdd50962b5f4f9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 278 6.6E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1713 f56c56134b248613eacdd50962b5f4f9 286 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 18 280 3.3E-81 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Spica_2569 560ead71ef5a306610c1d803b9a6bd1e 150 SUPERFAMILY SSF55804 3 149 2.09E-35 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2569 560ead71ef5a306610c1d803b9a6bd1e 150 Gene3D G3DSA:3.40.930.10 1 150 9.5E-43 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2569 560ead71ef5a306610c1d803b9a6bd1e 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 148 1.8E-33 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 Pfam PF00293 NUDIX domain 44 159 3.2E-15 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 PRINTS PR00502 NUDIX hydrolase family signature 76 90 2.1E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 PRINTS PR00502 NUDIX hydrolase family signature 90 105 2.1E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 SUPERFAMILY SSF55811 25 196 1.03E-28 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 ProSitePatterns PS00893 Nudix box signature. 81 102 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spica_2266 c47ddd3a5feaf09a32871d7b72f12b74 202 Gene3D G3DSA:3.90.79.10 22 198 2.8E-41 T 13-10-2018 Spica_2289 4770229c84a2f71b1d233bb2ef6c2766 227 PIRSF PIRSF006806 14 219 1.0E-36 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spica_2289 4770229c84a2f71b1d233bb2ef6c2766 227 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 18 214 2.4E-34 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spica_2289 4770229c84a2f71b1d233bb2ef6c2766 227 SUPERFAMILY SSF100950 18 214 6.7E-39 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_2289 4770229c84a2f71b1d233bb2ef6c2766 227 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 18 214 7.9E-35 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spica_2289 4770229c84a2f71b1d233bb2ef6c2766 227 Gene3D G3DSA:3.40.50.10420 8 221 1.3E-50 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Spica_2293 b26ee2494307c538b9c991cfb850fd50 170 Pfam PF08534 Redoxin 20 162 3.0E-19 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Spica_2293 b26ee2494307c538b9c991cfb850fd50 170 Gene3D G3DSA:3.40.30.10 1 168 9.1E-45 T 13-10-2018 Spica_2293 b26ee2494307c538b9c991cfb850fd50 170 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 13-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 Spica_2293 b26ee2494307c538b9c991cfb850fd50 170 Hamap MF_00269 Thiol peroxidase [tpx]. 3 166 35.66 T 13-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 Spica_2293 b26ee2494307c538b9c991cfb850fd50 170 SUPERFAMILY SSF52833 1 163 5.14E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_0961 41710dab5c674a4b5770c2f4ef67946d 149 Gene3D G3DSA:3.40.50.2300 19 145 1.1E-35 T 13-10-2018 Spica_0961 41710dab5c674a4b5770c2f4ef67946d 149 SUPERFAMILY SSF52172 23 144 1.57E-33 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0961 41710dab5c674a4b5770c2f4ef67946d 149 SMART SM00448 25 139 7.1E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0961 41710dab5c674a4b5770c2f4ef67946d 149 Pfam PF00072 Response regulator receiver domain 27 139 8.9E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 439 4.0E-92 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 SUPERFAMILY SSF53633 5 294 1.02E-42 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 SUPERFAMILY SSF55729 296 422 3.54E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 Gene3D G3DSA:3.40.630.30 293 440 3.4E-36 T 13-10-2018 Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 Pfam PF00696 Amino acid kinase family 37 268 2.5E-15 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 Pfam PF00583 Acetyltransferase (GNAT) family 335 404 7.2E-6 T 13-10-2018 IPR000182 GNAT domain Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 Gene3D G3DSA:3.40.1160.10 7 292 1.2E-69 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 440 103.078 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Spica_1973 4e376f39c7d9eb56c1065883375bd720 440 PIRSF PIRSF000423 1 440 4.5E-106 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 Spica_0714 126f6ad47341789e486a20e75e33578a 303 Gene3D G3DSA:1.10.3720.10 56 301 6.7E-57 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0714 126f6ad47341789e486a20e75e33578a 303 SUPERFAMILY SSF161098 60 289 4.32E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0714 126f6ad47341789e486a20e75e33578a 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 294 3.2E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1943 1f6133db054b44c36635256fc6c7f221 440 SUPERFAMILY SSF52777 18 138 4.6E-5 T 13-10-2018 Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 SMART SM00849 20 195 6.3E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 6 303 2.0E-106 T 13-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 Pfam PF12706 Beta-lactamase superfamily domain 34 154 1.2E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 Pfam PF12706 Beta-lactamase superfamily domain 201 271 9.8E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 Gene3D G3DSA:3.60.15.10 3 305 9.7E-89 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 SUPERFAMILY SSF56281 7 304 2.23E-76 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1285 0fd8331dab51df29db7777f03bf448a9 309 Hamap MF_01818 Ribonuclease BN [rbn]. 3 305 34.72 T 13-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 Spica_2506 9e53eff370444378453a5299e8d38dd0 281 Gene3D G3DSA:3.40.190.10 135 237 1.5E-69 T 13-10-2018 Spica_2506 9e53eff370444378453a5299e8d38dd0 281 Gene3D G3DSA:3.40.190.10 43 270 1.5E-69 T 13-10-2018 Spica_2506 9e53eff370444378453a5299e8d38dd0 281 SMART SM00062 44 275 8.9E-55 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2506 9e53eff370444378453a5299e8d38dd0 281 SUPERFAMILY SSF53850 15 271 1.72E-60 T 13-10-2018 Spica_2506 9e53eff370444378453a5299e8d38dd0 281 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 271 3.3E-55 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_0553 a2445b220074ed8be0f71cead9c7a635 300 Pfam PF01040 UbiA prenyltransferase family 21 271 4.2E-29 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Spica_0553 a2445b220074ed8be0f71cead9c7a635 300 PIRSF PIRSF005355 1 297 1.5E-43 T 13-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 Spica_1306 fc3efd268840c93156f502063b9000db 250 Gene3D G3DSA:1.10.3720.10 47 243 1.0E-18 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1306 fc3efd268840c93156f502063b9000db 250 SUPERFAMILY SSF161098 51 229 1.57E-21 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1306 fc3efd268840c93156f502063b9000db 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 231 5.3E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1927 09e2491dbc84c0be0fbb5c0415e17c60 626 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 3 622 3.4E-132 T 13-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Spica_1927 09e2491dbc84c0be0fbb5c0415e17c60 626 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 6 617 4.1E-165 T 13-10-2018 IPR010144 CRISPR-associated protein, Csd1-type Spica_2697 92f74195731d3d5f7c4d13b411d970fe 395 Gene3D G3DSA:3.90.220.20 181 359 2.2E-23 T 13-10-2018 Spica_2697 92f74195731d3d5f7c4d13b411d970fe 395 Gene3D G3DSA:3.90.220.20 1 180 9.1E-35 T 13-10-2018 Spica_2697 92f74195731d3d5f7c4d13b411d970fe 395 Pfam PF01420 Type I restriction modification DNA specificity domain 1 186 1.8E-21 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 Spica_2697 92f74195731d3d5f7c4d13b411d970fe 395 SUPERFAMILY SSF116734 203 394 5.07E-22 T 13-10-2018 Spica_2697 92f74195731d3d5f7c4d13b411d970fe 395 SUPERFAMILY SSF116734 3 198 9.48E-42 T 13-10-2018 Spica_2444 88259c279361fb3e415755c08f5c62cd 342 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 164 173 - T 13-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 Spica_2444 88259c279361fb3e415755c08f5c62cd 342 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 53 300 3.0E-59 T 13-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Spica_2444 88259c279361fb3e415755c08f5c62cd 342 SUPERFAMILY SSF51445 40 337 1.58E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2444 88259c279361fb3e415755c08f5c62cd 342 Gene3D G3DSA:3.20.20.80 33 338 3.6E-96 T 13-10-2018 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 Pfam PF13365 Trypsin-like peptidase domain 125 264 1.3E-32 T 13-10-2018 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 134 146 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 257 274 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 155 175 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 235 252 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 PRINTS PR00834 HtrA/DegQ protease family signature 358 370 5.0E-48 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 Gene3D G3DSA:2.30.42.10 300 417 5.8E-22 T 13-10-2018 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 Gene3D G3DSA:2.40.10.120 80 299 7.0E-74 T 13-10-2018 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 Pfam PF13180 PDZ domain 319 409 3.7E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 SUPERFAMILY SSF50156 262 401 9.45E-16 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_0684 41386202e1c3fcf79a41dd98a1f7a355 418 SUPERFAMILY SSF50494 91 300 2.62E-63 T 13-10-2018 IPR009003 Peptidase S1, PA clan Spica_2694 7e5705f47fa740959479c74165b0f394 134 SUPERFAMILY SSF81593 3 127 9.02E-43 T 13-10-2018 Spica_2694 7e5705f47fa740959479c74165b0f394 134 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 10 120 1.0E-31 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Spica_2694 7e5705f47fa740959479c74165b0f394 134 Gene3D G3DSA:1.20.120.330 11 130 5.1E-38 T 13-10-2018 Spica_2694 7e5705f47fa740959479c74165b0f394 134 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 9 129 3.1E-39 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Gene3D G3DSA:3.40.50.620 231 433 5.3E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 SUPERFAMILY SSF52402 215 474 4.85E-45 T 13-10-2018 Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 SUPERFAMILY SSF52317 2 255 8.54E-43 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Pfam PF00958 GMP synthase C terminal domain 462 552 1.1E-37 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Gene3D G3DSA:3.30.300.10 434 553 2.8E-48 T 13-10-2018 Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 SUPERFAMILY SSF54810 433 553 4.97E-48 T 13-10-2018 Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Pfam PF02540 NAD synthase 245 308 2.5E-5 T 13-10-2018 IPR022310 NAD/GMP synthase Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Pfam PF00117 Glutamine amidotransferase class-I 6 221 8.7E-28 T 13-10-2018 IPR017926 Glutamine amidotransferase Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 Gene3D G3DSA:3.40.50.880 1 226 7.0E-40 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Spica_1847 6a05d73263b93219a6dad3d3928bc6bf 553 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 236 553 5.7E-110 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Spica_1453 5b56ce8bc65387352d0c929bc5695eb4 365 Gene3D G3DSA:3.40.50.1970 4 167 6.4E-41 T 13-10-2018 Spica_1453 5b56ce8bc65387352d0c929bc5695eb4 365 PIRSF PIRSF001455 26 363 7.8E-88 T 13-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Spica_1453 5b56ce8bc65387352d0c929bc5695eb4 365 Pfam PF01761 3-dehydroquinate synthase 63 332 2.3E-77 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Spica_1453 5b56ce8bc65387352d0c929bc5695eb4 365 SUPERFAMILY SSF56796 12 348 1.57E-71 T 13-10-2018 Spica_1453 5b56ce8bc65387352d0c929bc5695eb4 365 Gene3D G3DSA:1.20.1090.10 169 363 2.8E-45 T 13-10-2018 Spica_2168 e3e7173a33e433ee12a3cea6ca59016b 259 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 19 147 1.4E-22 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_2168 e3e7173a33e433ee12a3cea6ca59016b 259 Gene3D G3DSA:3.40.930.10 9 152 5.0E-22 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_2168 e3e7173a33e433ee12a3cea6ca59016b 259 SUPERFAMILY SSF55804 14 147 8.63E-21 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_0143 c2aec231f32020c436460e7eb4e31fd4 353 SUPERFAMILY SSF51735 1 324 3.6E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0143 c2aec231f32020c436460e7eb4e31fd4 353 Gene3D G3DSA:3.40.50.720 1 337 7.0E-37 T 13-10-2018 Spica_0143 c2aec231f32020c436460e7eb4e31fd4 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 109 229 2.6E-12 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Spica_0398 d645c0a05350958e887ff9ab4b4170e7 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.986 T 13-10-2018 IPR023053 Ribosomal protein S14, type Z Spica_0398 d645c0a05350958e887ff9ab4b4170e7 61 Gene3D G3DSA:4.10.830.10 1 61 2.4E-28 T 13-10-2018 Spica_0398 d645c0a05350958e887ff9ab4b4170e7 61 SUPERFAMILY SSF57716 5 61 1.43E-21 T 13-10-2018 Spica_0398 d645c0a05350958e887ff9ab4b4170e7 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Spica_0398 d645c0a05350958e887ff9ab4b4170e7 61 Pfam PF00253 Ribosomal protein S14p/S29e 12 60 1.7E-25 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 SMART SM00028 140 173 0.044 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 SMART SM00028 103 136 23.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 SMART SM00028 178 211 2.3 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 Gene3D G3DSA:1.25.40.10 103 225 2.9E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 Pfam PF13432 Tetratricopeptide repeat 144 211 3.1E-10 T 13-10-2018 Spica_1381 d9a68d814f17caf2674e945e18d5401d 229 SUPERFAMILY SSF48452 103 223 1.06E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2106 2aeb9210bb2d7544a29aec62cc9c38ca 166 Gene3D G3DSA:1.20.58.1290 69 165 5.1E-22 T 13-10-2018 Spica_2106 2aeb9210bb2d7544a29aec62cc9c38ca 166 Pfam PF02559 CarD-like/TRCF domain 8 115 1.5E-13 T 13-10-2018 IPR003711 CarD-like/TRCF domain Spica_2106 2aeb9210bb2d7544a29aec62cc9c38ca 166 Gene3D G3DSA:2.30.30.840 2 68 1.3E-22 T 13-10-2018 Spica_2106 2aeb9210bb2d7544a29aec62cc9c38ca 166 SMART SM01058 7 117 2.5E-20 T 13-10-2018 IPR003711 CarD-like/TRCF domain Spica_2106 2aeb9210bb2d7544a29aec62cc9c38ca 166 SUPERFAMILY SSF141259 4 72 3.27E-11 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 SUPERFAMILY SSF46689 12 96 1.54E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 Gene3D G3DSA:1.10.357.10 64 206 1.3E-10 T 13-10-2018 Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 SUPERFAMILY SSF48498 91 186 2.78E-7 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 4.7E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spica_0745 3a999b975236ddd32507a4d0bcc24db1 223 Gene3D G3DSA:1.10.10.60 10 63 2.7E-16 T 13-10-2018 Spica_2520 ecc85bb555a892eca102191e7a6ce4e8 336 SUPERFAMILY SSF69917 36 321 5.49E-26 T 13-10-2018 IPR020080 Outer membrane adhesin/peptidase omptin GO:0004190 Spica_2520 ecc85bb555a892eca102191e7a6ce4e8 336 Gene3D G3DSA:2.40.128.90 28 332 2.0E-35 T 13-10-2018 Spica_2520 ecc85bb555a892eca102191e7a6ce4e8 336 Pfam PF01278 Omptin family 34 331 9.6E-32 T 13-10-2018 IPR000036 Peptidase A26, omptin GO:0004175|GO:0006508|GO:0009279 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 Gene3D G3DSA:1.20.1260.30 8 150 4.1E-45 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 Pfam PF02384 N-6 DNA Methylase 159 478 2.6E-117 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 SUPERFAMILY SSF53335 17 514 6.95E-143 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 Pfam PF12161 HsdM N-terminal domain 18 145 9.0E-27 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 Gene3D G3DSA:3.40.50.150 160 462 1.0E-116 T 13-10-2018 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 284 290 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 199 1.8E-20 T 13-10-2018 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 315 339 1.8E-20 T 13-10-2018 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 281 293 1.8E-20 T 13-10-2018 Spica_2702 0b8140b6196e2b299622e3ec6330592c 517 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 206 220 1.8E-20 T 13-10-2018 Spica_0633 48ce85a7b027275f4beb23d8c9502eba 369 Pfam PF07470 Glycosyl Hydrolase Family 88 27 368 1.9E-83 T 13-10-2018 IPR010905 Glycosyl hydrolase, family 88 Spica_0633 48ce85a7b027275f4beb23d8c9502eba 369 Gene3D G3DSA:1.50.10.10 9 369 1.3E-122 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_0633 48ce85a7b027275f4beb23d8c9502eba 369 SUPERFAMILY SSF48208 27 369 1.3E-60 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 136 6.8E-33 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 SUPERFAMILY SSF50129 1 176 6.85E-52 T 13-10-2018 IPR011032 GroES-like superfamily Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 SUPERFAMILY SSF51735 141 307 4.85E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 Pfam PF00107 Zinc-binding dehydrogenase 178 303 9.8E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 Gene3D G3DSA:3.40.50.720 154 289 1.5E-96 T 13-10-2018 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 Gene3D G3DSA:3.90.180.10 11 327 1.5E-96 T 13-10-2018 Spica_2850 11806e57ae8c2eb2a3990918f625079b 343 SMART SM00829 4 324 0.001 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Spica_0506 dc54097cd937aac9cd2557c2cdb775a2 86 SUPERFAMILY SSF81301 2 65 8.88E-5 T 13-10-2018 Spica_0506 dc54097cd937aac9cd2557c2cdb775a2 86 Gene3D G3DSA:3.30.460.10 1 86 1.5E-7 T 13-10-2018 Spica_2239 e1cec4233df635d05a902da15ea56575 228 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2239 e1cec4233df635d05a902da15ea56575 228 Pfam PF00005 ABC transporter 23 172 1.8E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2239 e1cec4233df635d05a902da15ea56575 228 SMART SM00382 32 220 3.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2239 e1cec4233df635d05a902da15ea56575 228 SUPERFAMILY SSF52540 4 223 6.58E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2239 e1cec4233df635d05a902da15ea56575 228 Gene3D G3DSA:3.40.50.300 1 227 2.3E-62 T 13-10-2018 Spica_1245 de64f2f3a67469967535553d54a92ca9 496 Gene3D G3DSA:3.40.640.10 44 289 3.3E-41 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1245 de64f2f3a67469967535553d54a92ca9 496 Pfam PF00266 Aminotransferase class-V 140 447 5.0E-38 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_1245 de64f2f3a67469967535553d54a92ca9 496 SUPERFAMILY SSF53383 26 458 2.8E-75 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1245 de64f2f3a67469967535553d54a92ca9 496 Gene3D G3DSA:3.90.1150.10 311 459 1.4E-26 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 Gene3D G3DSA:3.40.50.2300 82 314 3.9E-45 T 13-10-2018 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 13-10-2018 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 SMART SM00354 1 71 1.3E-25 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 SUPERFAMILY SSF53822 79 335 9.42E-34 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 SUPERFAMILY SSF47413 2 59 4.16E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 Gene3D G3DSA:3.40.50.2300 160 293 3.9E-45 T 13-10-2018 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 Pfam PF13377 Periplasmic binding protein-like domain 168 333 4.7E-24 T 13-10-2018 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 Gene3D G3DSA:1.10.260.40 1 60 8.3E-24 T 13-10-2018 Spica_0735 e8e18629069a4bc179623e6ef60555d7 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.7E-18 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_2077 8951ee2ec074b7f80aa13202decc3f3b 249 Pfam PF00899 ThiF family 11 155 1.0E-38 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Spica_2077 8951ee2ec074b7f80aa13202decc3f3b 249 Gene3D G3DSA:3.40.50.720 1 246 1.1E-78 T 13-10-2018 Spica_2077 8951ee2ec074b7f80aa13202decc3f3b 249 SUPERFAMILY SSF69572 4 242 5.76E-57 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Spica_0824 0668678b56b98fa2c96cd22808754487 261 SUPERFAMILY SSF49899 24 260 9.9E-75 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_0824 0668678b56b98fa2c96cd22808754487 261 Pfam PF00722 Glycosyl hydrolases family 16 61 256 5.3E-39 T 13-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Spica_0824 0668678b56b98fa2c96cd22808754487 261 Gene3D G3DSA:2.60.120.200 24 260 9.9E-86 T 13-10-2018 Spica_2486 17f62a3b1a80c6b510a86934340b1d9a 425 Gene3D G3DSA:3.40.50.2000 211 398 1.3E-18 T 13-10-2018 Spica_2486 17f62a3b1a80c6b510a86934340b1d9a 425 SUPERFAMILY SSF53756 12 418 3.24E-29 T 13-10-2018 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 Pfam PF00149 Calcineurin-like phosphoesterase 43 262 5.4E-13 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 Gene3D G3DSA:3.90.780.10 420 618 3.8E-44 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 Gene3D G3DSA:3.60.21.10 33 382 1.9E-110 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 Pfam PF02872 5'-nucleotidase, C-terminal domain 434 575 4.4E-33 T 13-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 SUPERFAMILY SSF55816 429 604 6.28E-41 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 SUPERFAMILY SSF56300 41 326 5.87E-86 T 13-10-2018 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 PRINTS PR01607 Apyrase family signature 227 244 6.3E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 PRINTS PR01607 Apyrase family signature 246 269 6.3E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 PRINTS PR01607 Apyrase family signature 471 494 6.3E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 PRINTS PR01607 Apyrase family signature 554 573 6.3E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_0137 fd973c2b1b266bc2d7e8f08b23c734b5 619 PRINTS PR01607 Apyrase family signature 40 58 6.3E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_2365 64f79328fed11b3f4434c52507e86e29 276 SUPERFAMILY SSF53335 71 276 1.11E-32 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2365 64f79328fed11b3f4434c52507e86e29 276 Pfam PF13649 Methyltransferase domain 76 171 9.0E-17 T 13-10-2018 Spica_2365 64f79328fed11b3f4434c52507e86e29 276 Gene3D G3DSA:2.20.25.110 179 234 3.1E-40 T 13-10-2018 Spica_2365 64f79328fed11b3f4434c52507e86e29 276 Gene3D G3DSA:3.40.50.150 74 259 3.1E-40 T 13-10-2018 Spica_2549 67b5a6ab007197953498917c50460327 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 302 8.2E-30 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 4 306 36.105 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 144 3.5E-45 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 Gene3D G3DSA:3.40.50.1370 5 301 5.5E-109 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 Gene3D G3DSA:3.40.50.1370 132 291 5.5E-109 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 5.4E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 5.4E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 5.4E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 5.4E-25 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 263 268 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 1.2E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 5 304 6.4E-104 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Spica_2549 67b5a6ab007197953498917c50460327 309 SUPERFAMILY SSF53671 2 305 1.7E-97 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Spica_2624 098e8ce19317bedad29580957c24c4f7 370 SUPERFAMILY SSF53613 14 361 7.95E-54 T 13-10-2018 IPR029056 Ribokinase-like Spica_2624 098e8ce19317bedad29580957c24c4f7 370 Gene3D G3DSA:3.40.1190.20 6 370 5.3E-98 T 13-10-2018 IPR029056 Ribokinase-like Spica_2624 098e8ce19317bedad29580957c24c4f7 370 Pfam PF00294 pfkB family carbohydrate kinase 37 351 6.0E-18 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_0748 319d9946f4878765473983627cabbb4b 755 Gene3D G3DSA:1.25.10.10 432 673 1.0E-14 T 13-10-2018 IPR011989 Armadillo-like helical Spica_0748 319d9946f4878765473983627cabbb4b 755 Pfam PF07690 Major Facilitator Superfamily 23 378 1.3E-8 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_0748 319d9946f4878765473983627cabbb4b 755 SUPERFAMILY SSF103473 19 420 1.26E-22 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_0748 319d9946f4878765473983627cabbb4b 755 Gene3D G3DSA:1.20.1250.20 223 421 2.3E-6 T 13-10-2018 Spica_0748 319d9946f4878765473983627cabbb4b 755 Gene3D G3DSA:1.20.1250.20 15 211 2.7E-5 T 13-10-2018 Spica_0748 319d9946f4878765473983627cabbb4b 755 SUPERFAMILY SSF48371 461 648 1.15E-17 T 13-10-2018 IPR016024 Armadillo-type fold Spica_0918 c9ba1d918611fbdfbfd99aa910073205 349 Gene3D G3DSA:3.40.50.2300 38 308 2.0E-111 T 13-10-2018 Spica_0918 c9ba1d918611fbdfbfd99aa910073205 349 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 40 345 2.2E-71 T 13-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 Spica_0918 c9ba1d918611fbdfbfd99aa910073205 349 SUPERFAMILY SSF53822 48 286 9.81E-9 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0918 c9ba1d918611fbdfbfd99aa910073205 349 Gene3D G3DSA:3.40.50.2300 140 341 2.0E-111 T 13-10-2018 Spica_2107 316f3f84cb361606eb1f97627defbc2b 241 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 240 3.1E-35 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Spica_2107 316f3f84cb361606eb1f97627defbc2b 241 Gene3D G3DSA:3.90.550.10 4 241 1.1E-53 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2107 316f3f84cb361606eb1f97627defbc2b 241 SUPERFAMILY SSF53448 6 240 2.1E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2107 316f3f84cb361606eb1f97627defbc2b 241 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 120 127 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Spica_0147 3e0049f4625b5960d5c6d610a6f306ff 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 266 1.8E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0147 3e0049f4625b5960d5c6d610a6f306ff 281 Gene3D G3DSA:1.10.3720.10 2 268 1.1E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0147 3e0049f4625b5960d5c6d610a6f306ff 281 SUPERFAMILY SSF161098 7 281 1.7E-62 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 Gene3D G3DSA:1.25.40.10 39 239 2.6E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 SUPERFAMILY SSF48452 76 218 6.83E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 Pfam PF13432 Tetratricopeptide repeat 165 216 1.1E-8 T 13-10-2018 Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 SMART SM00028 153 187 370.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 SMART SM00028 188 221 0.31 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1679 1c26a2cd6a68d58c7d1341a08d98583d 240 SMART SM00028 75 108 40.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 PIRSF PIRSF001413 1 397 2.1E-150 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 391 48.118 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 53 378 4.3E-48 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 Gene3D G3DSA:3.40.50.1100 9 205 4.4E-166 T 13-10-2018 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 Gene3D G3DSA:3.40.50.1100 53 384 4.4E-166 T 13-10-2018 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 386 4.3E-167 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0177 b6e6d5569e4c0c163e3bbc5b2e541112 430 SUPERFAMILY SSF53686 5 386 3.67E-130 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_0601 37c5950b14e5b720041aec3097284bfb 363 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 156 354 3.2E-62 T 13-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 Spica_0601 37c5950b14e5b720041aec3097284bfb 363 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 352 2.6E-130 T 13-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 Spica_0601 37c5950b14e5b720041aec3097284bfb 363 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 363 136.415 T 13-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 Spica_0601 37c5950b14e5b720041aec3097284bfb 363 SUPERFAMILY SSF51658 1 350 1.21E-74 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Spica_0601 37c5950b14e5b720041aec3097284bfb 363 Gene3D G3DSA:3.20.20.150 1 357 6.8E-131 T 13-10-2018 Spica_0601 37c5950b14e5b720041aec3097284bfb 363 PIRSF PIRSF016049 154 357 3.1E-71 T 13-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 Spica_0601 37c5950b14e5b720041aec3097284bfb 363 PIRSF PIRSF016049 1 169 2.9E-37 T 13-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 6.2E-27 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 PIRSF PIRSF004669 1 89 5.5E-29 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.0E-21 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.0E-21 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.0E-21 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Spica_1528 be6cbedd91699b3163ab7135bc90dbb2 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 1.7E-30 T 13-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 Spica_1024 530094b9a97a5d8a25cf94566fb9492a 194 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 3 183 9.5E-27 T 13-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 Spica_1024 530094b9a97a5d8a25cf94566fb9492a 194 SUPERFAMILY SSF55154 3 183 1.8E-25 T 13-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 Spica_1024 530094b9a97a5d8a25cf94566fb9492a 194 Gene3D G3DSA:2.40.320.10 2 189 1.2E-42 T 13-10-2018 Spica_1024 530094b9a97a5d8a25cf94566fb9492a 194 Pfam PF01928 CYTH domain 3 179 1.5E-13 T 13-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 Spica_1024 530094b9a97a5d8a25cf94566fb9492a 194 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 3 146 3.0E-8 T 13-10-2018 Spica_0940 1c1c8dd918e89ea0e9363e0154cbf163 175 Pfam PF00694 Aconitase C-terminal domain 55 111 2.5E-21 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Spica_0940 1c1c8dd918e89ea0e9363e0154cbf163 175 SUPERFAMILY SSF52016 3 174 1.18E-40 T 13-10-2018 Spica_0940 1c1c8dd918e89ea0e9363e0154cbf163 175 Gene3D G3DSA:3.20.19.10 1 165 4.5E-42 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Spica_2842 e35d77c0894baf861e784750ccae75e3 237 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 51 214 2.0E-18 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Spica_2842 e35d77c0894baf861e784750ccae75e3 237 SUPERFAMILY SSF55729 19 231 4.82E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2842 e35d77c0894baf861e784750ccae75e3 237 Gene3D G3DSA:3.40.630.70 65 236 6.3E-27 T 13-10-2018 Spica_0933 c076ebb7e97d19860aeecac7cb5ac48f 894 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 297 669 6.5E-45 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Spica_0933 c076ebb7e97d19860aeecac7cb5ac48f 894 SUPERFAMILY SSF56059 327 668 4.47E-30 T 13-10-2018 Spica_0933 c076ebb7e97d19860aeecac7cb5ac48f 894 Gene3D G3DSA:3.30.1490.20 327 471 3.6E-15 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_2789 80f498cd563c6b0133b1db4fc52ac6da 125 SMART SM00448 2 116 1.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2789 80f498cd563c6b0133b1db4fc52ac6da 125 SUPERFAMILY SSF52172 2 121 8.82E-28 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2789 80f498cd563c6b0133b1db4fc52ac6da 125 Pfam PF00072 Response regulator receiver domain 4 116 1.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2789 80f498cd563c6b0133b1db4fc52ac6da 125 Gene3D G3DSA:3.40.50.2300 2 124 1.0E-26 T 13-10-2018 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 PIRSF PIRSF000728 13 293 6.0E-108 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 Hamap MF_00082 Acetylglutamate kinase [argB]. 27 286 48.752 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 Gene3D G3DSA:3.40.1160.10 4 299 4.5E-99 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 SUPERFAMILY SSF53633 6 294 2.49E-87 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 8.7E-10 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 8.7E-10 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 PRINTS PR00474 Glutamate 5-kinase family signature 155 176 8.7E-10 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 PRINTS PR00474 Glutamate 5-kinase family signature 190 217 8.7E-10 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 Pfam PF00696 Amino acid kinase family 28 270 6.6E-45 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Spica_0885 04c8d3076b53b787650e5ddd14faf3c1 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 268 7.3E-77 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 Gene3D G3DSA:3.40.190.10 131 224 2.5E-72 T 13-10-2018 Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 Gene3D G3DSA:3.40.190.10 47 266 2.5E-72 T 13-10-2018 Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 13-10-2018 IPR018313 Solute-binding protein family 3, conserved site Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 SMART SM00062 45 268 7.4E-70 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 SUPERFAMILY SSF53850 1 269 4.16E-72 T 13-10-2018 Spica_1899 9075ad985d9a383f3ffa5e8b7a0d3cc9 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 266 2.2E-67 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_1635 22c84254532fbbff27885ecd0d2acfcc 244 SUPERFAMILY SSF53448 1 202 2.15E-22 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1635 22c84254532fbbff27885ecd0d2acfcc 244 Gene3D G3DSA:3.90.550.10 1 206 9.3E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1635 22c84254532fbbff27885ecd0d2acfcc 244 Pfam PF02348 Cytidylyltransferase 5 200 4.0E-30 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 Spica_2133 344b675ceeda275e7e32b8b1cc3316e1 330 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2133 344b675ceeda275e7e32b8b1cc3316e1 330 SUPERFAMILY SSF52540 35 252 4.62E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2133 344b675ceeda275e7e32b8b1cc3316e1 330 SMART SM00382 47 231 1.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2133 344b675ceeda275e7e32b8b1cc3316e1 330 Gene3D G3DSA:3.40.50.300 25 285 6.0E-55 T 13-10-2018 Spica_2133 344b675ceeda275e7e32b8b1cc3316e1 330 Pfam PF00005 ABC transporter 39 182 1.2E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Gene3D G3DSA:1.10.486.10 374 544 3.1E-119 T 13-10-2018 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Gene3D G3DSA:3.40.50.300 271 632 3.1E-119 T 13-10-2018 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Gene3D G3DSA:3.40.50.300 10 264 2.2E-91 T 13-10-2018 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 SUPERFAMILY SSF52540 8 641 1.58E-163 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Pfam PF13361 UvrD-like helicase C-terminal domain 268 615 1.5E-76 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Pfam PF00580 UvrD/REP helicase N-terminal domain 161 262 1.1E-37 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 128 2.6E-36 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Spica_1251 d78b60adca9b3afeeeffe258065fc2fc 667 Gene3D G3DSA:1.10.10.160 110 182 2.2E-91 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 SMART SM00304 309 364 1.1E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 SMART SM00283 365 598 4.6E-66 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Pfam PF02743 Cache domain 43 271 5.4E-28 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 SUPERFAMILY SSF103190 88 190 2.75E-13 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Gene3D G3DSA:1.10.287.950 309 599 9.7E-77 T 13-10-2018 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 425 565 3.9E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 SUPERFAMILY SSF58104 338 598 3.53E-63 T 13-10-2018 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Gene3D G3DSA:3.30.450.20 68 184 1.4E-34 T 13-10-2018 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Gene3D G3DSA:3.30.450.20 56 270 1.4E-34 T 13-10-2018 Spica_1169 e0881dd2231a774f4f54aad64a9b3cff 612 Pfam PF00672 HAMP domain 309 361 4.3E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 Gene3D G3DSA:3.90.180.10 14 353 3.5E-33 T 13-10-2018 Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 SUPERFAMILY SSF51735 168 338 1.03E-14 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 98 4.4E-7 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 Pfam PF00107 Zinc-binding dehydrogenase 187 330 2.0E-10 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 Gene3D G3DSA:3.40.50.720 156 320 3.5E-33 T 13-10-2018 Spica_1988 ea10924cb4b03989617eac27e4ab50a2 420 SUPERFAMILY SSF50129 3 172 4.25E-20 T 13-10-2018 IPR011032 GroES-like superfamily Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 133 143 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 4 21 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 32 43 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 169 182 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 147 158 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 PRINTS PR00988 Uridine kinase signature 77 92 1.4E-37 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 Hamap MF_00551 Uridine kinase [udk]. 1 203 37.776 T 13-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 SUPERFAMILY SSF52540 5 193 9.84E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 TIGRFAM TIGR00235 udk: uridine kinase 4 202 4.2E-83 T 13-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 Gene3D G3DSA:3.40.50.300 5 204 1.8E-63 T 13-10-2018 Spica_2737 5a33ec79a3df39df0ad63c5a9b6c0e1e 204 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 187 2.4E-46 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 Spica_2510 1d100966d89b24c2aec6440fb2cb598d 332 Pfam PF12697 Alpha/beta hydrolase family 99 316 1.2E-14 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Spica_2510 1d100966d89b24c2aec6440fb2cb598d 332 SUPERFAMILY SSF53474 63 332 1.07E-38 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2510 1d100966d89b24c2aec6440fb2cb598d 332 Gene3D G3DSA:3.40.50.1820 78 332 2.2E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 SUPERFAMILY SSF52440 1 109 1.42E-31 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Gene3D G3DSA:3.30.1490.20 129 206 6.1E-18 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Gene3D G3DSA:3.30.470.20 207 352 5.0E-43 T 13-10-2018 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 108 3.0E-34 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 459 5.6E-133 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 SUPERFAMILY SSF56059 110 345 2.05E-47 T 13-10-2018 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 313 320 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 SMART SM01209 109 319 7.7E-84 T 13-10-2018 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Gene3D G3DSA:3.40.50.20 2 101 2.6E-35 T 13-10-2018 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 SUPERFAMILY SSF51246 353 459 1.8E-18 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 459 35.079 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 109 319 4.3E-57 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Gene3D G3DSA:3.90.600.10 354 460 4.5E-26 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 355 459 9.9E-25 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2418 6c6eed50c551278d3eb7e6d0cd1ed6a2 460 SMART SM01210 353 458 6.4E-24 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 759 805 1.5E-10 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 550 1.0E-11 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 654 1.8E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 658 705 9.8E-14 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 755 1.5E-6 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 554 600 1.9E-5 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 470 5.7E-158 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 SUPERFAMILY SSF101904 499 818 4.19E-96 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 807 24.195 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Gene3D G3DSA:2.120.10.90 496 806 1.8E-111 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 806 0.0 T 13-10-2018 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 SUPERFAMILY SSF56719 30 487 2.88E-176 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 SMART SM00434 11 464 1.1E-276 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Gene3D G3DSA:1.10.268.10 369 457 8.7E-211 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Gene3D G3DSA:3.30.1360.40 236 332 8.7E-211 T 13-10-2018 Spica_2868 fa0e8f88549df54688b944a7a8aac2de 837 Gene3D G3DSA:3.90.199.10 32 486 8.7E-211 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Spica_1637 2761e4b07722127e05a4f0bf1e7563a6 534 SUPERFAMILY SSF102114 241 528 2.22E-25 T 13-10-2018 Spica_1637 2761e4b07722127e05a4f0bf1e7563a6 534 Gene3D G3DSA:3.20.20.70 244 532 4.8E-27 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1637 2761e4b07722127e05a4f0bf1e7563a6 534 TIGRFAM TIGR04321 spiroSPASM: spiro-SPASM protein 4 534 1.1E-200 T 13-10-2018 IPR027608 Spirochetes SPASM protein Spica_1637 2761e4b07722127e05a4f0bf1e7563a6 534 Pfam PF13186 Iron-sulfur cluster-binding domain 464 527 1.2E-9 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain Spica_1934 baa049266a507472a63bd007be2a5b18 109 PIRSF PIRSF029883 1 109 2.2E-28 T 13-10-2018 IPR025499 Pectin degradation protein KdgF Spica_1934 baa049266a507472a63bd007be2a5b18 109 SUPERFAMILY SSF51182 7 103 1.29E-26 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_1934 baa049266a507472a63bd007be2a5b18 109 Pfam PF07883 Cupin domain 32 97 2.3E-17 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Spica_1934 baa049266a507472a63bd007be2a5b18 109 Gene3D G3DSA:2.60.120.10 1 108 9.7E-31 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 44 104 2.1E-24 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 11 28 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 Gene3D G3DSA:2.30.30.30 1 104 2.6E-39 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 6 99 21.783 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 Pfam PF00467 KOW motif 12 41 6.1E-9 T 13-10-2018 IPR005824 KOW Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 6 104 3.0E-37 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 SMART SM00739 7 34 5.4E-5 T 13-10-2018 IPR005824 KOW Spica_0396 ff496b799062ef8659caa4c7a67fab7d 105 SUPERFAMILY SSF50104 4 103 1.73E-33 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_0650 1a5885bd4cb1913151dafe44aeee3c6f 331 Pfam PF03116 NQR2, RnfD, RnfE family 4 320 2.6E-106 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Spica_0650 1a5885bd4cb1913151dafe44aeee3c6f 331 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 1 324 23.595 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Spica_0650 1a5885bd4cb1913151dafe44aeee3c6f 331 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 6 322 4.3E-89 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Gene3D G3DSA:3.10.20.30 35 126 7.8E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00410 Phenol hydroxylase reductase family signature 165 177 9.1E-18 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00410 Phenol hydroxylase reductase family signature 231 240 9.1E-18 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00410 Phenol hydroxylase reductase family signature 246 265 9.1E-18 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00410 Phenol hydroxylase reductase family signature 344 352 9.1E-18 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 38 115 1.1E-9 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 SUPERFAMILY SSF54292 35 123 1.31E-20 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 SUPERFAMILY SSF52343 227 374 6.29E-35 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Gene3D G3DSA:3.40.50.80 238 377 6.8E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 187 194 3.0E-8 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 344 352 3.0E-8 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 273 282 3.0E-8 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 285 296 3.0E-8 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 246 265 3.0E-8 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 SUPERFAMILY SSF63380 106 242 3.56E-29 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Gene3D G3DSA:2.40.30.10 127 234 1.7E-27 T 13-10-2018 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Pfam PF00175 Oxidoreductase NAD-binding domain 247 357 6.9E-20 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Spica_1722 40c9e75a4fc4880388d1b8f83ea3925f 377 Pfam PF00970 Oxidoreductase FAD-binding domain 135 236 7.1E-13 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 Spica_2733 1ca5fb4f440450b9ecdaba46a708f4c5 259 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 110 231 4.3E-36 T 13-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 Spica_2733 1ca5fb4f440450b9ecdaba46a708f4c5 259 Gene3D G3DSA:3.30.1380.10 45 251 4.8E-59 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Spica_2733 1ca5fb4f440450b9ecdaba46a708f4c5 259 SUPERFAMILY SSF55166 100 238 2.3E-33 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Spica_2236 58d2879bd6849721ef1c9387a8301835 252 Gene3D G3DSA:2.50.20.10 24 252 1.2E-49 T 13-10-2018 Spica_2236 58d2879bd6849721ef1c9387a8301835 252 Pfam PF17131 Outer membrane lipoprotein-sorting protein 73 252 9.2E-48 T 13-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein Spica_2236 58d2879bd6849721ef1c9387a8301835 252 SUPERFAMILY SSF89392 49 246 3.92E-5 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spica_1567 acad2a7333e1bdc07eaafd4795b92ac0 133 Gene3D G3DSA:3.40.50.1010 1 127 3.4E-18 T 13-10-2018 Spica_1567 acad2a7333e1bdc07eaafd4795b92ac0 133 Pfam PF01850 PIN domain 3 124 5.6E-7 T 13-10-2018 IPR002716 PIN domain Spica_1567 acad2a7333e1bdc07eaafd4795b92ac0 133 SUPERFAMILY SSF88723 1 124 1.43E-12 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1216 40827c5cf4240293676b6485195eede1 405 Gene3D G3DSA:3.40.640.10 53 294 3.0E-139 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1216 40827c5cf4240293676b6485195eede1 405 Gene3D G3DSA:3.90.1150.10 21 398 3.0E-139 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1216 40827c5cf4240293676b6485195eede1 405 Pfam PF00155 Aminotransferase class I and II 36 395 2.9E-45 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_1216 40827c5cf4240293676b6485195eede1 405 SUPERFAMILY SSF53383 5 399 2.58E-91 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2505 f748df7d79fee91c79eb969a539f2365 232 Gene3D G3DSA:1.10.3720.10 1 230 1.3E-66 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2505 f748df7d79fee91c79eb969a539f2365 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 227 2.6E-26 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2505 f748df7d79fee91c79eb969a539f2365 232 SUPERFAMILY SSF161098 10 212 5.89E-50 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2505 f748df7d79fee91c79eb969a539f2365 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 121 2.2E-25 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Spica_2330 bc74089a0d39c77470c9d3626702517f 587 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 13-10-2018 IPR020845 AMP-binding, conserved site Spica_2330 bc74089a0d39c77470c9d3626702517f 587 SUPERFAMILY SSF56801 6 584 8.5E-112 T 13-10-2018 Spica_2330 bc74089a0d39c77470c9d3626702517f 587 Pfam PF00501 AMP-binding enzyme 36 452 2.1E-92 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Spica_2330 bc74089a0d39c77470c9d3626702517f 587 Gene3D G3DSA:3.40.50.12780 3 450 2.8E-94 T 13-10-2018 Spica_1917 0d2d2cc5e127e5d6bb3c2c0834c9dfc3 255 SUPERFAMILY SSF52467 8 252 1.31E-74 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_1917 0d2d2cc5e127e5d6bb3c2c0834c9dfc3 255 Gene3D G3DSA:3.30.1600.10 41 179 7.6E-74 T 13-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily Spica_1917 0d2d2cc5e127e5d6bb3c2c0834c9dfc3 255 Pfam PF02146 Sir2 family 32 208 5.8E-51 T 13-10-2018 IPR003000 Sirtuin family GO:0070403 Spica_1917 0d2d2cc5e127e5d6bb3c2c0834c9dfc3 255 Gene3D G3DSA:3.40.50.1220 26 245 7.6E-74 T 13-10-2018 Spica_0188 41037b29257af3f4577d26f4f849761d 174 Gene3D G3DSA:1.20.1200.10 12 174 3.7E-50 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Spica_0188 41037b29257af3f4577d26f4f849761d 174 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 170 3.0E-30 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Spica_0188 41037b29257af3f4577d26f4f849761d 174 Pfam PF01923 Cobalamin adenosyltransferase 3 163 1.3E-51 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Spica_0188 41037b29257af3f4577d26f4f849761d 174 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 5 169 4.8E-53 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Spica_0188 41037b29257af3f4577d26f4f849761d 174 SUPERFAMILY SSF89028 1 169 1.86E-49 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 SUPERFAMILY SSF52540 79 355 1.35E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 4.1E-65 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 SUPERFAMILY SSF47917 362 421 5.23E-5 T 13-10-2018 Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 74 1.1E-8 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 Gene3D G3DSA:3.40.50.12240 2 458 1.8E-168 T 13-10-2018 Spica_1815 20b5a6ec829c52c3e874ae4daf7e982f 487 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 56.502 T 13-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1901 7521a40164ec9fb8f4ec2410cee3f3fe 240 Pfam PF01171 PP-loop family 26 188 5.1E-13 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Spica_1901 7521a40164ec9fb8f4ec2410cee3f3fe 240 Gene3D G3DSA:3.40.50.620 2 240 7.5E-40 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1901 7521a40164ec9fb8f4ec2410cee3f3fe 240 PIRSF PIRSF004976 2 240 1.8E-49 T 13-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 Spica_1901 7521a40164ec9fb8f4ec2410cee3f3fe 240 SUPERFAMILY SSF52402 4 211 7.06E-41 T 13-10-2018 Spica_2790 3a102bcdfc381331e6cbdfbfaa5559a3 260 Pfam PF00588 SpoU rRNA Methylase family 108 251 1.3E-28 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Spica_2790 3a102bcdfc381331e6cbdfbfaa5559a3 260 SUPERFAMILY SSF75217 103 254 3.47E-32 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_2790 3a102bcdfc381331e6cbdfbfaa5559a3 260 Gene3D G3DSA:3.40.1280.10 96 255 1.3E-41 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_1401 020d7c2747743b77b1fc6b6209bd5235 175 Pfam PF01230 HIT domain 44 133 1.1E-13 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Spica_1401 020d7c2747743b77b1fc6b6209bd5235 175 SUPERFAMILY SSF54197 25 155 8.97E-30 T 13-10-2018 IPR036265 HIT-like superfamily Spica_1401 020d7c2747743b77b1fc6b6209bd5235 175 Gene3D G3DSA:3.30.428.10 2 174 7.7E-35 T 13-10-2018 IPR036265 HIT-like superfamily Spica_1656 5fad324ff8adc74e22603114c924e948 151 Hamap MF_00526 Glutamate mutase sigma subunit [glmS]. 1 142 38.755 T 13-10-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1656 5fad324ff8adc74e22603114c924e948 151 SUPERFAMILY SSF52242 2 142 1.83E-36 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Spica_1656 5fad324ff8adc74e22603114c924e948 151 TIGRFAM TIGR01501 MthylAspMutase: methylaspartate mutase, S subunit 10 140 6.2E-62 T 13-10-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1656 5fad324ff8adc74e22603114c924e948 151 Gene3D G3DSA:3.40.50.280 1 151 8.4E-41 T 13-10-2018 Spica_1656 5fad324ff8adc74e22603114c924e948 151 Pfam PF02310 B12 binding domain 10 108 2.8E-16 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 SUPERFAMILY SSF52172 1 180 4.07E-36 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 Gene3D G3DSA:3.40.50.2300 1 122 3.8E-32 T 13-10-2018 Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 SMART SM00862 149 225 3.7E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 Pfam PF00072 Response regulator receiver domain 4 112 6.7E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 SMART SM00448 2 112 2.4E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 Gene3D G3DSA:1.10.10.10 127 227 3.1E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2603 159375f47ecd887d4d9f19f06b30e790 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 225 7.4E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_2171 a1440b4c5ff23971880fd3346cc47e1a 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 6.3E-50 T 13-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 Spica_2171 a1440b4c5ff23971880fd3346cc47e1a 128 Pfam PF01042 Endoribonuclease L-PSP 10 128 3.3E-42 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Spica_2171 a1440b4c5ff23971880fd3346cc47e1a 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 104 122 - T 13-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 Spica_2171 a1440b4c5ff23971880fd3346cc47e1a 128 Gene3D G3DSA:3.30.1330.40 1 128 6.0E-55 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Spica_2171 a1440b4c5ff23971880fd3346cc47e1a 128 SUPERFAMILY SSF55298 1 128 1.88E-45 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 25 177 2.3E-58 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 24 80 6.1E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 SUPERFAMILY SSF52374 22 177 3.05E-42 T 13-10-2018 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 23 179 32.169 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 41 62 4.2E-39 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 23 41 4.2E-39 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 70 94 4.2E-39 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 133 155 4.2E-39 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 106 122 4.2E-39 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 Gene3D G3DSA:3.40.50.620 23 182 5.5E-54 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1407 2e04a282237d4712c84a2f6db07640d9 183 Pfam PF01467 Cytidylyltransferase-like 27 154 5.8E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Gene3D G3DSA:3.40.50.300 274 643 3.8E-99 T 13-10-2018 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Gene3D G3DSA:1.10.10.160 108 182 3.8E-89 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily Spica_0463 60f384a309ee43c7109d21b31746220c 762 Pfam PF13361 UvrD-like helicase C-terminal domain 515 622 2.4E-29 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 264 4.6E-70 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Gene3D G3DSA:3.40.50.300 8 265 3.8E-89 T 13-10-2018 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Pfam PF13361 UvrD-like helicase C-terminal domain 270 424 2.0E-32 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Spica_0463 60f384a309ee43c7109d21b31746220c 762 Gene3D G3DSA:1.10.486.10 376 547 3.8E-99 T 13-10-2018 Spica_0463 60f384a309ee43c7109d21b31746220c 762 SUPERFAMILY SSF52540 1 647 1.33E-151 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2644 c0d7b2f738a03a20da82260f3aba0994 427 Gene3D G3DSA:3.40.50.150 112 340 8.9E-11 T 13-10-2018 Spica_2644 c0d7b2f738a03a20da82260f3aba0994 427 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 112 316 4.7E-12 T 13-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 Spica_2644 c0d7b2f738a03a20da82260f3aba0994 427 SUPERFAMILY SSF53335 107 292 3.25E-12 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2704 67aabbb52cdad554566f7e502f32957b 68 SUPERFAMILY SSF143100 4 58 1.2E-19 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like Spica_2704 67aabbb52cdad554566f7e502f32957b 68 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 6 59 5.7E-12 T 13-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system Spica_2704 67aabbb52cdad554566f7e502f32957b 68 Gene3D G3DSA:3.30.160.250 3 68 5.7E-20 T 13-10-2018 Spica_2232 687ce177d4d556a0b20c4fd203afdb07 166 SUPERFAMILY SSF53756 1 151 1.47E-6 T 13-10-2018 Spica_2232 687ce177d4d556a0b20c4fd203afdb07 166 Pfam PF13528 Glycosyl transferase family 1 1 135 2.4E-19 T 13-10-2018 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 Gene3D G3DSA:3.40.50.2300 154 279 1.5E-70 T 13-10-2018 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 Gene3D G3DSA:3.40.50.2300 61 300 1.5E-70 T 13-10-2018 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 Gene3D G3DSA:1.10.260.40 1 57 5.0E-18 T 13-10-2018 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.8E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.8E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 2.3E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 Pfam PF13377 Periplasmic binding protein-like domain 163 319 1.1E-31 T 13-10-2018 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 SUPERFAMILY SSF53822 60 320 1.16E-64 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 SMART SM00354 1 70 2.7E-29 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0814 cd356537b0ca56a92d25b2411a95b2f3 324 SUPERFAMILY SSF47413 2 58 4.44E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_1880 a762c16da13e14a4fb79bf73ac5c5632 106 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 23 76 5.0E-8 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_1880 a762c16da13e14a4fb79bf73ac5c5632 106 SUPERFAMILY SSF143120 21 71 1.96E-6 T 13-10-2018 IPR036165 YefM-like superfamily Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 PIRSF PIRSF000239 4 215 5.9E-70 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 Gene3D G3DSA:3.40.30.10 10 148 2.0E-40 T 13-10-2018 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 202 1.6E-11 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 Gene3D G3DSA:3.30.1020.20 149 215 6.0E-26 T 13-10-2018 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 Hamap MF_00401 Peroxiredoxin. 9 215 47.236 T 13-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 Pfam PF00578 AhpC/TSA family 12 139 3.3E-26 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Spica_0708 eb083483a04ade2fe731a3353aed64b8 215 SUPERFAMILY SSF52833 7 214 3.87E-62 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_1905 38010e1863427b2d6429029c22ae1215 705 Pfam PF07695 7TM diverse intracellular signalling 208 407 3.5E-16 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 Spica_1905 38010e1863427b2d6429029c22ae1215 705 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 508 701 2.4E-27 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1905 38010e1863427b2d6429029c22ae1215 705 Gene3D G3DSA:3.60.40.10 444 703 6.4E-48 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1905 38010e1863427b2d6429029c22ae1215 705 SMART SM00331 478 703 9.2E-22 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2455 1de90a9f7248f46c6d7cf763174bb402 517 Gene3D G3DSA:2.60.120.200 321 513 2.3E-29 T 13-10-2018 Spica_2455 1de90a9f7248f46c6d7cf763174bb402 517 SUPERFAMILY SSF49899 322 512 3.48E-21 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_2455 1de90a9f7248f46c6d7cf763174bb402 517 Gene3D G3DSA:2.115.10.20 14 302 5.7E-71 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2455 1de90a9f7248f46c6d7cf763174bb402 517 Pfam PF04616 Glycosyl hydrolases family 43 19 288 8.1E-60 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Spica_2455 1de90a9f7248f46c6d7cf763174bb402 517 SUPERFAMILY SSF75005 19 296 4.58E-73 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 Pfam PF00166 Chaperonin 10 Kd subunit 3 87 1.4E-27 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 SMART SM00883 2 87 2.5E-38 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 SUPERFAMILY SSF50129 1 88 8.01E-27 T 13-10-2018 IPR011032 GroES-like superfamily Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 PRINTS PR00297 10kDa chaperonin signature 25 46 9.7E-25 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 PRINTS PR00297 10kDa chaperonin signature 3 18 9.7E-25 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 PRINTS PR00297 10kDa chaperonin signature 53 65 9.7E-25 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 PRINTS PR00297 10kDa chaperonin signature 74 87 9.7E-25 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 Gene3D G3DSA:2.30.33.40 1 88 4.8E-29 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 Spica_0926 950972fb497aaeb9fe551a6e8c8933d3 88 Hamap MF_00580 10 kDa chaperonin [groS]. 2 88 21.82 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Hamap MF_00069 Hydroxylamine reductase [hcp]. 3 552 23.196 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Gene3D G3DSA:1.20.1270.20 147 230 2.9E-29 T 13-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 3 549 1.6E-222 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Gene3D G3DSA:3.40.50.2030 232 381 3.6E-65 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 SUPERFAMILY SSF56821 3 552 8.24E-208 T 13-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Gene3D G3DSA:3.40.50.2030 382 551 7.7E-63 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Pfam PF03063 Prismane/CO dehydrogenase family 3 548 4.2E-175 T 13-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 PIRSF PIRSF000076 3 553 4.5E-253 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0028 d83d80397ce6ac086a1d8945a7b9463e 553 Gene3D G3DSA:1.20.1270.20 1 145 1.9E-38 T 13-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 Spica_0977 4965394dd6af0aa7953f8a50398a50a5 337 Pfam PF00152 tRNA synthetases class II (D, K and N) 5 334 1.3E-36 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Spica_0977 4965394dd6af0aa7953f8a50398a50a5 337 Gene3D G3DSA:3.30.930.10 1 335 1.3E-82 T 13-10-2018 Spica_0977 4965394dd6af0aa7953f8a50398a50a5 337 SUPERFAMILY SSF55681 5 334 1.75E-63 T 13-10-2018 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 SUPERFAMILY SSF69765 1 157 2.09E-56 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 32.932 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 Pfam PF02542 YgbB family 2 156 5.1E-58 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 156 4.5E-59 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_2108 53d238f10841a20cd2cf94622b3d8071 160 Gene3D G3DSA:3.30.1330.50 1 160 8.0E-61 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Spica_1818 2fad8a7c4f4d8388708b5caaddb8e3ae 113 SUPERFAMILY SSF159468 4 113 7.19E-13 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1818 2fad8a7c4f4d8388708b5caaddb8e3ae 113 Gene3D G3DSA:3.40.50.10580 4 111 2.6E-13 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1818 2fad8a7c4f4d8388708b5caaddb8e3ae 113 Pfam PF01990 ATP synthase (F/14-kDa) subunit 5 95 1.0E-9 T 13-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 247 1.8E-65 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 Gene3D G3DSA:3.30.420.40 251 487 6.5E-65 T 13-10-2018 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 PIRSF PIRSF000538 1 495 1.5E-118 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 TIGRFAM TIGR01312 XylB: xylulokinase 6 485 6.0E-170 T 13-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 SUPERFAMILY SSF53067 3 249 4.17E-63 T 13-10-2018 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 372 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 Gene3D G3DSA:3.30.420.40 1 248 3.9E-74 T 13-10-2018 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 SUPERFAMILY SSF53067 249 494 4.16E-55 T 13-10-2018 Spica_2746 9b2ff4053557ca97e785e9330fb4110c 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 438 1.0E-25 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 Pfam PF13181 Tetratricopeptide repeat 143 173 0.01 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 Gene3D G3DSA:1.25.40.10 22 138 3.4E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SMART SM00028 104 137 100.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SMART SM00028 175 208 3.4E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SMART SM00028 70 103 13.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SMART SM00028 141 174 0.051 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SMART SM00028 36 69 320.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 SUPERFAMILY SSF48452 41 211 3.87E-29 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 Gene3D G3DSA:1.25.40.10 139 223 2.7E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0138 ac0385cbdc53b1da29c558626ca13abd 223 Pfam PF07719 Tetratricopeptide repeat 177 207 5.2E-7 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Spica_0531 da790c3861990a01247b6979b985897f 75 SUPERFAMILY SSF143120 1 50 1.31E-5 T 13-10-2018 IPR036165 YefM-like superfamily Spica_2052 fa93f187e6168ae5d66ce2e31d6fab6c 215 Pfam PF01914 MarC family integral membrane protein 3 206 3.1E-53 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Spica_2052 fa93f187e6168ae5d66ce2e31d6fab6c 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 204 1.8E-49 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Spica_0569 e970d5c4709094cfd48df62b44b692d5 132 Gene3D G3DSA:3.40.50.1010 1 131 6.5E-34 T 13-10-2018 Spica_0569 e970d5c4709094cfd48df62b44b692d5 132 Pfam PF01850 PIN domain 2 122 3.4E-15 T 13-10-2018 IPR002716 PIN domain Spica_0569 e970d5c4709094cfd48df62b44b692d5 132 SUPERFAMILY SSF88723 1 131 1.63E-34 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2435 5c2b0af47a114e46f2b3d9b750071a76 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 257 3.4E-106 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Spica_2435 5c2b0af47a114e46f2b3d9b750071a76 258 Pfam PF00977 Histidine biosynthesis protein 5 240 6.0E-81 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Spica_2435 5c2b0af47a114e46f2b3d9b750071a76 258 Gene3D G3DSA:3.20.20.70 1 258 5.2E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2435 5c2b0af47a114e46f2b3d9b750071a76 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 257 45.605 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Spica_2435 5c2b0af47a114e46f2b3d9b750071a76 258 SUPERFAMILY SSF51366 1 257 4.37E-81 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 152 3.8E-39 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 185 261 1.0E-21 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 SUPERFAMILY SSF117143 98 240 1.83E-27 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 Pfam PF00460 Flagella basal body rod protein 6 35 3.0E-11 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 259 1.8E-58 T 13-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 Spica_1474 ddd718b4f7fcd68f885ee35d350a652a 282 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 204 277 1.6E-24 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1616 90602fa11091d45dd71fc45189627966 413 SUPERFAMILY SSF81301 23 204 3.11E-33 T 13-10-2018 Spica_1616 90602fa11091d45dd71fc45189627966 413 SMART SM00954 50 176 1.2E-18 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Spica_1616 90602fa11091d45dd71fc45189627966 413 Pfam PF00515 Tetratricopeptide repeat 366 397 7.3E-9 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 Pfam PF04607 Region found in RelA / SpoT proteins 50 172 3.7E-24 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Spica_1616 90602fa11091d45dd71fc45189627966 413 SUPERFAMILY SSF48452 259 400 3.67E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 Gene3D G3DSA:1.25.40.10 253 338 7.4E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 Gene3D G3DSA:1.25.40.10 339 413 6.5E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 Gene3D G3DSA:3.30.460.10 9 157 1.0E-23 T 13-10-2018 Spica_1616 90602fa11091d45dd71fc45189627966 413 SMART SM00028 364 397 4.0E-7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 SMART SM00028 296 329 0.0021 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 SMART SM00028 330 363 0.069 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 SMART SM00028 259 292 1.9 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1616 90602fa11091d45dd71fc45189627966 413 Pfam PF13432 Tetratricopeptide repeat 267 318 1.9E-6 T 13-10-2018 Spica_0981 6ddc97c866ddfcaa95e96de691929e66 348 Pfam PF10974 Protein of unknown function (DUF2804) 22 347 1.4E-76 T 13-10-2018 IPR021243 Protein of unknown function DUF2804 Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 SUPERFAMILY SSF52402 157 306 1.42E-16 T 13-10-2018 Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 Gene3D G3DSA:3.40.50.620 1 144 1.4E-27 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 SUPERFAMILY SSF52402 1 143 3.35E-25 T 13-10-2018 Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 PRINTS PR01438 Universal stress protein signature 121 143 2.9E-14 T 13-10-2018 IPR006015 Universal stress protein A Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 PRINTS PR01438 Universal stress protein signature 103 115 2.9E-14 T 13-10-2018 IPR006015 Universal stress protein A Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 PRINTS PR01438 Universal stress protein signature 2 20 2.9E-14 T 13-10-2018 IPR006015 Universal stress protein A Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 Gene3D G3DSA:3.40.50.620 156 307 1.0E-17 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 Pfam PF00582 Universal stress protein family 1 142 5.3E-20 T 13-10-2018 IPR006016 UspA Spica_2166 97ea9808168f236400434d3f55f2a3d0 307 Pfam PF00582 Universal stress protein family 158 305 8.2E-11 T 13-10-2018 IPR006016 UspA Spica_2538 198ea0ab4f8727fedef9b3244472a84d 309 SUPERFAMILY SSF161098 90 292 2.13E-19 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2538 198ea0ab4f8727fedef9b3244472a84d 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 307 3.3E-37 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2538 198ea0ab4f8727fedef9b3244472a84d 309 Gene3D G3DSA:1.10.3720.10 82 307 8.9E-22 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1590 28064b1c79bec6ad80d6ac2b1b0bf7d4 175 Pfam PF02517 CAAX protease self-immunity 80 168 7.6E-15 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Spica_0310 7262907fcbbd4ff32838693a8c41215b 435 Pfam PF01547 Bacterial extracellular solute-binding protein 53 352 2.7E-40 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0310 7262907fcbbd4ff32838693a8c41215b 435 Gene3D G3DSA:3.40.190.10 56 392 1.2E-110 T 13-10-2018 Spica_0310 7262907fcbbd4ff32838693a8c41215b 435 Gene3D G3DSA:3.40.190.10 156 426 1.2E-110 T 13-10-2018 Spica_0310 7262907fcbbd4ff32838693a8c41215b 435 SUPERFAMILY SSF53850 35 434 5.02E-80 T 13-10-2018 Spica_2071 2d80e08d1319f8a5ffbe145139b27471 438 SUPERFAMILY SSF53743 4 301 7.32E-42 T 13-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 Spica_2071 2d80e08d1319f8a5ffbe145139b27471 438 SUPERFAMILY SSF50443 311 437 7.32E-5 T 13-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal Spica_1613 a256d84c92b651717b50f231dc5919d1 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 50 68 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site Spica_1613 a256d84c92b651717b50f231dc5919d1 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 9.2E-32 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Spica_1613 a256d84c92b651717b50f231dc5919d1 148 Pfam PF02082 Transcriptional regulator 1 83 1.5E-22 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Spica_1613 a256d84c92b651717b50f231dc5919d1 148 Gene3D G3DSA:1.10.10.10 1 143 3.5E-38 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1613 a256d84c92b651717b50f231dc5919d1 148 SUPERFAMILY SSF46785 2 135 2.83E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 Pfam PF13175 AAA ATPase domain 1 42 1.6E-12 T 13-10-2018 Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 Gene3D G3DSA:3.40.50.300 1 71 1.5E-11 T 13-10-2018 Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 SUPERFAMILY SSF52540 1 318 2.39E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 Gene3D G3DSA:3.40.50.300 137 324 9.3E-9 T 13-10-2018 Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 215 309 4.2E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Spica_2080 f95b543e424bf51adcfca19ca891fa14 557 SMART SM00382 20 325 1.6E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0989 63f5723987117d303c711fda459ec7cc 495 SMART SM00845 323 487 6.7E-24 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Spica_0989 63f5723987117d303c711fda459ec7cc 495 SUPERFAMILY SSF55931 5 289 1.9E-111 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Spica_0989 63f5723987117d303c711fda459ec7cc 495 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 488 33.32 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Spica_0989 63f5723987117d303c711fda459ec7cc 495 Pfam PF02637 GatB domain 323 487 1.2E-22 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Spica_0989 63f5723987117d303c711fda459ec7cc 495 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 140 154 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Spica_0989 63f5723987117d303c711fda459ec7cc 495 SUPERFAMILY SSF89095 292 407 4.97E-21 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Spica_0989 63f5723987117d303c711fda459ec7cc 495 Pfam PF02934 GatB/GatE catalytic domain 5 282 3.4E-106 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Spica_0989 63f5723987117d303c711fda459ec7cc 495 Gene3D G3DSA:1.10.150.380 296 416 1.8E-24 T 13-10-2018 Spica_0989 63f5723987117d303c711fda459ec7cc 495 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 487 1.1E-145 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 ProSitePatterns PS00818 Dps protein family signature 1. 26 42 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 Gene3D G3DSA:1.20.1260.10 2 144 3.6E-44 T 13-10-2018 IPR012347 Ferritin-like Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 SUPERFAMILY SSF47240 5 143 1.67E-35 T 13-10-2018 IPR009078 Ferritin-like superfamily Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 50 66 1.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 26 42 1.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 1.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 PIRSF PIRSF005900 1 145 1.5E-42 T 13-10-2018 IPR002177 DNA-binding protein Dps Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 Pfam PF00210 Ferritin-like domain 6 142 2.7E-24 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spica_0702 ec1a955f92393d0c6a9717377dd7a416 145 ProSitePatterns PS00819 Dps protein family signature 2. 52 66 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 117 255 2.7E-29 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 21 253 21.298 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 PIRSF PIRSF003078 2 31 360.0 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 PIRSF PIRSF003078 26 256 5.4E-43 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 Pfam PF02527 rRNA small subunit methyltransferase G 112 252 5.5E-29 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 Pfam PF02527 rRNA small subunit methyltransferase G 32 74 9.0E-6 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Spica_2406 fcc8bc369a59e45b4ccd367d467b4749 256 SUPERFAMILY SSF53335 31 255 4.18E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1671 4e1f83ee46bb084b8b90e73d9c218076 125 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 52 125 6.0E-17 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Spica_1671 4e1f83ee46bb084b8b90e73d9c218076 125 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 90 106 2.9E-7 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Spica_1671 4e1f83ee46bb084b8b90e73d9c218076 125 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 111 124 2.9E-7 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Spica_1671 4e1f83ee46bb084b8b90e73d9c218076 125 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 55 71 2.9E-7 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Spica_1671 4e1f83ee46bb084b8b90e73d9c218076 125 Pfam PF02049 Flagellar hook-basal body complex protein FliE 49 124 6.0E-16 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 PRINTS PR00103 cAMP-dependent protein kinase signature 69 80 1.2E-6 T 13-10-2018 Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 PRINTS PR00103 cAMP-dependent protein kinase signature 28 42 1.2E-6 T 13-10-2018 Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 PRINTS PR00103 cAMP-dependent protein kinase signature 57 66 1.2E-6 T 13-10-2018 Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 PRINTS PR00103 cAMP-dependent protein kinase signature 13 27 1.2E-6 T 13-10-2018 Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 Pfam PF00027 Cyclic nucleotide-binding domain 11 95 7.4E-23 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 59 76 - T 13-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 SUPERFAMILY SSF51206 10 118 1.44E-29 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 SMART SM00100 1 109 4.5E-14 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0773 8d88d6e03019c8444a6ef1300e6753d3 211 Gene3D G3DSA:2.60.120.1460 5 205 4.0E-33 T 13-10-2018 Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 Pfam PF01668 SmpB protein 8 149 1.5E-58 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 8 131 2.0E-45 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 ProSitePatterns PS01317 SsrA-binding protein. 26 38 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 Hamap MF_00023 SsrA-binding protein [smpB]. 1 153 66.329 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 SUPERFAMILY SSF74982 3 131 2.35E-49 T 13-10-2018 IPR023620 Small protein B Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 Gene3D G3DSA:2.40.280.10 1 128 1.0E-47 T 13-10-2018 IPR023620 Small protein B Spica_1298 624d0e3f95780c6bef6e364bc6d12060 153 TIGRFAM TIGR00086 smpB: SsrA-binding protein 7 148 1.1E-58 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Spica_2422 47de608e12d0adaedcbaa77a9fb77c9d 552 SUPERFAMILY SSF53850 22 543 5.98E-76 T 13-10-2018 Spica_2422 47de608e12d0adaedcbaa77a9fb77c9d 552 Gene3D G3DSA:3.40.190.10 155 538 2.2E-53 T 13-10-2018 Spica_2422 47de608e12d0adaedcbaa77a9fb77c9d 552 Pfam PF13416 Bacterial extracellular solute-binding protein 60 372 2.5E-16 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2422 47de608e12d0adaedcbaa77a9fb77c9d 552 Gene3D G3DSA:3.40.190.10 59 442 2.2E-53 T 13-10-2018 Spica_2615 98c812da1a7f78f0f782d2acf5d6d9ac 1255 SMART SM00642 327 722 0.0022 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_2615 98c812da1a7f78f0f782d2acf5d6d9ac 1255 SUPERFAMILY SSF51445 342 803 2.44E-55 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2615 98c812da1a7f78f0f782d2acf5d6d9ac 1255 Pfam PF00128 Alpha amylase, catalytic domain 352 708 5.9E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 SUPERFAMILY SSF51905 2 346 1.2E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 365 472 6.6E-29 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 Gene3D G3DSA:3.50.50.60 5 343 7.0E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PIRSF PIRSF000350 1 482 2.1E-82 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 338 4.4E-64 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 Gene3D G3DSA:3.30.390.30 364 484 1.7E-38 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 SUPERFAMILY SSF55424 361 483 4.81E-34 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 9.8E-35 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.8E-35 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 9.8E-35 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 9.8E-35 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 9.8E-35 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 483 3.6E-153 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 448 468 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 382 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 441 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 3.4E-66 T 13-10-2018 Spica_1707 afaf68dc071f94c4507983ccdcf67746 484 Gene3D G3DSA:3.50.50.60 152 284 7.0E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 SUPERFAMILY SSF56176 348 437 3.82E-22 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 Gene3D G3DSA:3.10.580.10 198 351 1.4E-33 T 13-10-2018 Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 Pfam PF03471 Transporter associated domain 352 430 4.8E-20 T 13-10-2018 IPR005170 Transporter-associated domain Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 Pfam PF01595 Domain of unknown function DUF21 10 202 3.7E-41 T 13-10-2018 IPR002550 CNNM, transmembrane domain Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 Gene3D G3DSA:3.30.465.10 352 431 3.9E-27 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 SMART SM01091 351 432 1.0E-26 T 13-10-2018 IPR005170 Transporter-associated domain Spica_1213 252bb0ac8ec0eac45c758fea2a3605ae 442 SUPERFAMILY SSF54631 205 340 1.36E-20 T 13-10-2018 Spica_1571 ac1e269be15cb86d44198dba85ab7ceb 180 SUPERFAMILY SSF52218 1 108 4.19E-16 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_1571 ac1e269be15cb86d44198dba85ab7ceb 180 Gene3D G3DSA:3.40.50.360 1 134 5.0E-20 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_1892 c483e98dd5b601312f2601f7076bc549 217 Pfam PF00857 Isochorismatase family 9 213 1.2E-35 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 Spica_1892 c483e98dd5b601312f2601f7076bc549 217 SUPERFAMILY SSF52499 2 215 3.4E-52 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Spica_1892 c483e98dd5b601312f2601f7076bc549 217 Gene3D G3DSA:3.40.50.850 6 216 8.4E-67 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 Pfam PF02872 5'-nucleotidase, C-terminal domain 374 564 1.1E-31 T 13-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 Pfam PF00149 Calcineurin-like phosphoesterase 53 282 3.0E-7 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 SUPERFAMILY SSF55816 370 618 2.62E-38 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 Gene3D G3DSA:3.60.21.10 44 372 3.6E-64 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 Gene3D G3DSA:3.90.780.10 376 600 7.0E-53 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 PRINTS PR01607 Apyrase family signature 50 68 3.9E-18 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 PRINTS PR01607 Apyrase family signature 231 248 3.9E-18 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 PRINTS PR01607 Apyrase family signature 543 562 3.9E-18 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 PRINTS PR01607 Apyrase family signature 436 459 3.9E-18 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 PRINTS PR01607 Apyrase family signature 265 288 3.9E-18 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 Spica_1845 8c22ecf42252927fa01fac2a5c191968 637 SUPERFAMILY SSF56300 48 371 5.61E-64 T 13-10-2018 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 TIGRFAM TIGR00277 HDIG: HDIG domain 319 396 1.1E-24 T 13-10-2018 IPR006675 HDIG domain Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Pfam PF00013 KH domain 199 257 4.3E-8 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Pfam PF12072 Domain of unknown function (DUF3552) 4 191 4.3E-45 T 13-10-2018 IPR022711 Ribonuclease Y, N-terminal Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Pfam PF01966 HD domain 323 415 1.2E-21 T 13-10-2018 IPR006674 HD domain Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 SUPERFAMILY SSF109604 305 457 2.04E-32 T 13-10-2018 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 507 1.2E-216 T 13-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 SMART SM00471 319 425 2.6E-14 T 13-10-2018 IPR003607 HD/PDEase domain Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Gene3D G3DSA:1.10.3210.10 312 483 6.7E-20 T 13-10-2018 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 SUPERFAMILY SSF54791 197 291 1.23E-17 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Gene3D G3DSA:3.30.1370.10 195 290 3.3E-9 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 Hamap MF_00335 Ribonuclease Y [rny]. 3 507 23.95 T 13-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 Spica_2759 47c28c25ccb7b096cb1300c4727a044e 507 SMART SM00322 195 262 6.1E-9 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Spica_1227 c26186cc5bac2a485832130a6d97e9b2 342 Pfam PF02562 PhoH-like protein 135 338 8.2E-84 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 Spica_1227 c26186cc5bac2a485832130a6d97e9b2 342 Gene3D G3DSA:3.40.50.300 132 338 1.2E-70 T 13-10-2018 Spica_1227 c26186cc5bac2a485832130a6d97e9b2 342 SUPERFAMILY SSF52540 134 310 5.7E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0149 27eed1946a72c3e50c771a34497b2348 408 Gene3D G3DSA:3.40.190.10 139 388 3.6E-123 T 13-10-2018 Spica_0149 27eed1946a72c3e50c771a34497b2348 408 SUPERFAMILY SSF53850 20 401 1.68E-78 T 13-10-2018 Spica_0149 27eed1946a72c3e50c771a34497b2348 408 Gene3D G3DSA:3.40.190.10 40 351 3.6E-123 T 13-10-2018 Spica_0149 27eed1946a72c3e50c771a34497b2348 408 Pfam PF01547 Bacterial extracellular solute-binding protein 37 326 5.5E-46 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2092 fcdfbf5a4cfa402d51646ae87137dee4 144 Gene3D G3DSA:1.10.10.10 1 139 2.9E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2092 fcdfbf5a4cfa402d51646ae87137dee4 144 SUPERFAMILY SSF46785 2 132 8.83E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2092 fcdfbf5a4cfa402d51646ae87137dee4 144 Pfam PF02082 Transcriptional regulator 1 80 4.3E-20 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Spica_1197 ead2f11bebc7e63b16d9563ca9e236d5 63 Pfam PF01192 RNA polymerase Rpb6 10 57 2.7E-6 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Spica_1197 ead2f11bebc7e63b16d9563ca9e236d5 63 SMART SM01409 7 59 2.4E-4 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Spica_1197 ead2f11bebc7e63b16d9563ca9e236d5 63 Gene3D G3DSA:3.90.940.10 2 63 4.4E-6 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Spica_1197 ead2f11bebc7e63b16d9563ca9e236d5 63 SUPERFAMILY SSF63562 5 60 2.79E-7 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Spica_2009 3c5045bab83ac9cfda4d5211bc2b2940 370 Gene3D G3DSA:3.40.50.2300 33 340 2.7E-118 T 13-10-2018 Spica_2009 3c5045bab83ac9cfda4d5211bc2b2940 370 Gene3D G3DSA:3.40.50.2300 135 361 2.7E-118 T 13-10-2018 Spica_2009 3c5045bab83ac9cfda4d5211bc2b2940 370 SUPERFAMILY SSF53822 32 352 1.23E-52 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2009 3c5045bab83ac9cfda4d5211bc2b2940 370 Pfam PF13407 Periplasmic binding protein domain 33 320 1.1E-51 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_2391 3a9fe7d2108618c1a9e2b966ae047696 284 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 228 2.2E-42 T 13-10-2018 Spica_2391 3a9fe7d2108618c1a9e2b966ae047696 284 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 283 1.4E-40 T 13-10-2018 IPR010106 Recombination-promoting nuclease RpnA Spica_1866 8ac9fad3562f0c8a9bdc6f0667d73884 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 336 2.4E-50 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1533 fc80f30cb822a2d72d702877e47966d5 185 Pfam PF03748 Flagellar basal body-associated protein FliL 104 180 1.1E-5 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 159 177 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 240 254 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 156 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 189 206 2.9E-47 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 Gene3D G3DSA:1.10.490.80 594 692 5.0E-12 T 13-10-2018 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 Gene3D G3DSA:1.10.8.540 504 592 3.8E-35 T 13-10-2018 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 Pfam PF00771 FHIPEP family 28 684 1.1E-251 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 PIRSF PIRSF005419 2 695 5.1E-248 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 Gene3D G3DSA:3.40.30.60 361 503 4.0E-56 T 13-10-2018 Spica_1525 4b2c97f7113251a1ea3c2b2aa01b80c5 695 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 17 692 2.0E-262 T 13-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 Spica_2342 b8b3428f08900265d3019839887bcf69 161 Pfam PF01584 CheW-like domain 8 147 9.8E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_2342 b8b3428f08900265d3019839887bcf69 161 SMART SM00260 3 144 7.2E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_2342 b8b3428f08900265d3019839887bcf69 161 Gene3D G3DSA:2.40.50.180 26 139 2.7E-38 T 13-10-2018 Spica_2342 b8b3428f08900265d3019839887bcf69 161 SUPERFAMILY SSF50341 6 148 2.35E-35 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_2342 b8b3428f08900265d3019839887bcf69 161 Gene3D G3DSA:2.30.30.40 9 138 2.7E-38 T 13-10-2018 Spica_0935 12013204bcb65ca8db351307378165ca 334 Gene3D G3DSA:3.30.70.1360 99 322 1.9E-56 T 13-10-2018 IPR036984 NrpR domain superfamily Spica_0935 12013204bcb65ca8db351307378165ca 334 Gene3D G3DSA:1.10.10.10 3 97 3.4E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0935 12013204bcb65ca8db351307378165ca 334 Pfam PF01995 Domain of unknown function DUF128 85 322 1.3E-79 T 13-10-2018 IPR002846 NrpR regulatory domain Spica_0935 12013204bcb65ca8db351307378165ca 334 Gene3D G3DSA:3.30.70.1360 169 294 1.9E-56 T 13-10-2018 IPR036984 NrpR domain superfamily Spica_0935 12013204bcb65ca8db351307378165ca 334 SUPERFAMILY SSF46785 10 89 4.38E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0935 12013204bcb65ca8db351307378165ca 334 Pfam PF08461 Ribonuclease R winged-helix domain 12 75 1.5E-16 T 13-10-2018 IPR013668 Ribonuclease R winged-helix domain Spica_2160 f6ea5090c504944cfc7103cfb748d63b 90 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 73 1.4E-7 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_2160 f6ea5090c504944cfc7103cfb748d63b 90 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 25 54 5.7E-6 T 13-10-2018 Spica_2160 f6ea5090c504944cfc7103cfb748d63b 90 SUPERFAMILY SSF143120 3 81 5.06E-14 T 13-10-2018 IPR036165 YefM-like superfamily Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 SUPERFAMILY SSF54862 54 133 3.95E-19 T 13-10-2018 Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 Gene3D G3DSA:3.30.70.260 5 75 8.7E-9 T 13-10-2018 Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 Pfam PF09383 NIL domain 7 71 3.6E-11 T 13-10-2018 IPR018449 NIL domain Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 Pfam PF14697 4Fe-4S dicluster domain 81 132 5.8E-9 T 13-10-2018 Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 SMART SM00930 1 74 1.1E-9 T 13-10-2018 IPR018449 NIL domain Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 SUPERFAMILY SSF55021 5 71 3.55E-12 T 13-10-2018 Spica_1548 b9dd4e00ebdac0adbed1ad3e6cca2589 137 Gene3D G3DSA:3.30.70.20 77 134 8.5E-14 T 13-10-2018 Spica_2379 4364dbe6011db21dbb3f4224cd16ebef 333 Gene3D G3DSA:3.40.50.410 91 290 1.7E-40 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2379 4364dbe6011db21dbb3f4224cd16ebef 333 Pfam PF00092 von Willebrand factor type A domain 92 285 1.4E-18 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_2379 4364dbe6011db21dbb3f4224cd16ebef 333 SUPERFAMILY SSF53300 89 288 5.64E-29 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2379 4364dbe6011db21dbb3f4224cd16ebef 333 SMART SM00327 90 281 1.0E-11 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_0070 a70dadff0baaa9b2fd0e2a971c6f52de 179 Pfam PF07694 5TMR of 5TMR-LYT 53 153 2.6E-5 T 13-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 Spica_0070 a70dadff0baaa9b2fd0e2a971c6f52de 179 Gene3D G3DSA:1.10.1760.20 24 176 2.4E-8 T 13-10-2018 Spica_0647 93acea95ffc3ac4da96f199869394c37 191 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 1 190 23.532 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Spica_0647 93acea95ffc3ac4da96f199869394c37 191 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 189 1.0E-53 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_0647 93acea95ffc3ac4da96f199869394c37 191 PIRSF PIRSF006102 1 191 9.1E-56 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_0647 93acea95ffc3ac4da96f199869394c37 191 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 2 190 1.8E-69 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 Spica_2810 6504d812ba21cc3bc21d89606c437e06 140 SUPERFAMILY SSF53146 1 138 3.66E-23 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_2810 6504d812ba21cc3bc21d89606c437e06 140 Gene3D G3DSA:3.30.420.130 1 139 2.5E-30 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_2810 6504d812ba21cc3bc21d89606c437e06 140 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 128 1.3E-14 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Spica_2600 9ee0be08df9c2214d4294b56c11690ce 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 59 259 2.2E-26 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2600 9ee0be08df9c2214d4294b56c11690ce 264 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 35 153 6.8E-13 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 Spica_2600 9ee0be08df9c2214d4294b56c11690ce 264 Gene3D G3DSA:1.10.3720.10 30 262 3.7E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2600 9ee0be08df9c2214d4294b56c11690ce 264 SUPERFAMILY SSF161098 37 244 4.71E-43 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 Gene3D G3DSA:1.10.3210.10 354 564 1.2E-68 T 13-10-2018 Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 SUPERFAMILY SSF109604 366 550 1.22E-37 T 13-10-2018 Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 Gene3D G3DSA:3.30.450.40 218 349 1.1E-12 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 SUPERFAMILY SSF55781 222 345 1.88E-14 T 13-10-2018 Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 SMART SM00471 373 522 3.1E-11 T 13-10-2018 IPR003607 HD/PDEase domain Spica_2612 f2bba03d8cad30ab2294af556e8105cd 566 Pfam PF01966 HD domain 378 512 1.7E-17 T 13-10-2018 IPR006674 HD domain Spica_2274 1e036b29ef16df2d8a038b2782b39489 124 Gene3D G3DSA:1.20.1560.10 2 124 1.9E-7 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2274 1e036b29ef16df2d8a038b2782b39489 124 SUPERFAMILY SSF90123 18 119 1.12E-7 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_0760 cb49e7d7f6010779d15ae6ed2c65f365 254 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 22 252 3.3E-79 T 13-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 Spica_0760 cb49e7d7f6010779d15ae6ed2c65f365 254 Gene3D G3DSA:3.40.50.1580 12 254 2.3E-64 T 13-10-2018 Spica_0760 cb49e7d7f6010779d15ae6ed2c65f365 254 Pfam PF01048 Phosphorylase superfamily 34 252 2.3E-32 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Spica_0760 cb49e7d7f6010779d15ae6ed2c65f365 254 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 79 94 - T 13-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 Spica_0760 cb49e7d7f6010779d15ae6ed2c65f365 254 SUPERFAMILY SSF53167 20 253 4.71E-78 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Spica_0343 e3bace85703d4341c0226dfe4a82805e 154 SUPERFAMILY SSF88723 18 134 3.64E-20 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0343 e3bace85703d4341c0226dfe4a82805e 154 Pfam PF01850 PIN domain 19 135 1.2E-13 T 13-10-2018 IPR002716 PIN domain Spica_0343 e3bace85703d4341c0226dfe4a82805e 154 Gene3D G3DSA:3.40.50.1010 18 143 9.4E-18 T 13-10-2018 Spica_0216 2a425822d530dd2acf74179da6653a69 142 SUPERFAMILY SSF88723 1 129 1.01E-20 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0216 2a425822d530dd2acf74179da6653a69 142 Gene3D G3DSA:3.40.50.1010 4 133 2.3E-11 T 13-10-2018 Spica_0216 2a425822d530dd2acf74179da6653a69 142 Pfam PF01850 PIN domain 6 124 2.7E-11 T 13-10-2018 IPR002716 PIN domain Spica_2630 75b8d34436cb7ba5d45602d5c854fba4 334 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 45 294 1.5E-70 T 13-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 Spica_2630 75b8d34436cb7ba5d45602d5c854fba4 334 Gene3D G3DSA:3.40.190.170 35 334 6.6E-109 T 13-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily Spica_2630 75b8d34436cb7ba5d45602d5c854fba4 334 PIRSF PIRSF006470 4 334 2.1E-96 T 13-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 Spica_2630 75b8d34436cb7ba5d45602d5c854fba4 334 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 318 8.0E-85 T 13-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 Spica_0838 f889ed57509a57fb6b301b9d8ed0d5b9 256 Gene3D G3DSA:3.40.50.300 2 253 3.3E-60 T 13-10-2018 Spica_0838 f889ed57509a57fb6b301b9d8ed0d5b9 256 SUPERFAMILY SSF52540 3 252 1.84E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0838 f889ed57509a57fb6b301b9d8ed0d5b9 256 SMART SM00382 29 229 1.3E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0838 f889ed57509a57fb6b301b9d8ed0d5b9 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 252 1.3E-10 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spica_0838 f889ed57509a57fb6b301b9d8ed0d5b9 256 Pfam PF00005 ABC transporter 21 180 2.1E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0034 718ec1e282bdfad024c689c83a2d0870 346 Gene3D G3DSA:3.40.50.2300 46 313 1.4E-89 T 13-10-2018 Spica_0034 718ec1e282bdfad024c689c83a2d0870 346 Gene3D G3DSA:3.40.50.2300 137 332 1.4E-89 T 13-10-2018 Spica_0034 718ec1e282bdfad024c689c83a2d0870 346 Pfam PF13407 Periplasmic binding protein domain 50 290 4.8E-51 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0034 718ec1e282bdfad024c689c83a2d0870 346 SUPERFAMILY SSF53822 30 325 1.07E-57 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_1033 19c60dbff773a78abfd2f1b1548a246a 200 SUPERFAMILY SSF53271 2 177 3.67E-24 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_1033 19c60dbff773a78abfd2f1b1548a246a 200 Gene3D G3DSA:3.40.50.2020 1 197 6.3E-29 T 13-10-2018 Spica_1033 19c60dbff773a78abfd2f1b1548a246a 200 Pfam PF00156 Phosphoribosyl transferase domain 14 121 6.5E-11 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Spica_1740 4d4d75e46dc98a678219ec3fe3883258 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 35 5.2E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spica_1740 4d4d75e46dc98a678219ec3fe3883258 83 SUPERFAMILY SSF47598 1 37 3.71E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1735 4d4d75e46dc98a678219ec3fe3883258 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 35 5.2E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 Spica_1735 4d4d75e46dc98a678219ec3fe3883258 83 SUPERFAMILY SSF47598 1 37 3.71E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 Gene3D G3DSA:1.10.1040.10 163 284 1.0E-33 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 275 6.8E-32 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 SUPERFAMILY SSF48179 163 274 3.51E-33 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 SUPERFAMILY SSF51735 3 162 1.68E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 1.1E-51 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 Gene3D G3DSA:3.40.50.720 1 162 2.3E-53 T 13-10-2018 Spica_2828 f3a95afe0f903064cdf9648f274d1b7e 319 PIRSF PIRSF000103 1 285 3.1E-69 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Spica_1179 e0609c7408d3a14774a2eab3afa72910 453 SUPERFAMILY SSF51998 4 448 2.38E-175 T 13-10-2018 Spica_1179 e0609c7408d3a14774a2eab3afa72910 453 Hamap MF_01221 UPF0210 protein . 3 453 51.79 T 13-10-2018 IPR007841 Uncharacterised protein family UPF0210 Spica_1179 e0609c7408d3a14774a2eab3afa72910 453 Pfam PF05167 Uncharacterised ACR (DUF711) 15 417 3.5E-179 T 13-10-2018 IPR007841 Uncharacterised protein family UPF0210 Spica_1179 e0609c7408d3a14774a2eab3afa72910 453 Gene3D G3DSA:3.20.70.20 3 453 2.3E-177 T 13-10-2018 Spica_1326 e6bfc542e65463fd5a77b6958dc2b9cc 182 Gene3D G3DSA:2.60.120.10 3 182 8.7E-74 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_1326 e6bfc542e65463fd5a77b6958dc2b9cc 182 SUPERFAMILY SSF51182 4 177 7.29E-76 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_1326 e6bfc542e65463fd5a77b6958dc2b9cc 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 3.4E-75 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_1326 e6bfc542e65463fd5a77b6958dc2b9cc 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 174 6.1E-75 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_1326 e6bfc542e65463fd5a77b6958dc2b9cc 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 7 172 3.0E-60 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 32 379 1.2E-82 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 Gene3D G3DSA:3.40.640.10 1 276 7.4E-89 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 21 378 1.3E-157 T 13-10-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 Gene3D G3DSA:3.90.1150.10 278 381 7.5E-17 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 SUPERFAMILY SSF53383 20 378 1.28E-95 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0508 42e227673ae3d21d737ac466dd13b7a8 382 PIRSF PIRSF000390 17 381 1.6E-90 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 Gene3D G3DSA:1.10.3810.10 57 255 2.8E-66 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 Pfam PF00905 Penicillin binding protein transpeptidase domain 424 725 3.1E-23 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 Gene3D G3DSA:3.40.710.10 399 789 4.1E-95 T 13-10-2018 Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 Gene3D G3DSA:3.40.710.10 268 346 6.9E-6 T 13-10-2018 Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 SUPERFAMILY SSF56601 221 792 3.52E-105 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 SUPERFAMILY SSF53955 53 257 2.36E-65 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 Pfam PF00912 Transglycosylase 64 239 6.2E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_0855 ec4371c950550fcc2b0aac17beab6790 862 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 75 731 3.5E-183 T 13-10-2018 Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 Gene3D G3DSA:1.10.1040.10 188 318 6.9E-35 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 188 312 3.6E-31 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 SUPERFAMILY SSF48179 188 312 3.91E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 SUPERFAMILY SSF51735 4 108 2.21E-9 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 Gene3D G3DSA:3.40.50.720 5 186 8.6E-25 T 13-10-2018 Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 314 7.2E-58 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 Spica_2845 8ebc424f117d8669c670340cc15e7eb7 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 156 6.3E-19 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain Spica_1241 7c1350b0f0be7714e44ca5d47c5b4506 179 Pfam PF02151 UvrB/uvrC motif 149 177 3.3E-6 T 13-10-2018 IPR001943 UVR domain GO:0005515 Spica_1241 7c1350b0f0be7714e44ca5d47c5b4506 179 PIRSF PIRSF015034 1 179 1.8E-32 T 13-10-2018 IPR025542 YacH protein Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 Pfam PF00005 ABC transporter 374 522 4.5E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 SUPERFAMILY SSF90123 22 342 6.02E-66 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 SMART SM00382 382 568 1.1E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 Gene3D G3DSA:1.20.1560.10 2 342 2.2E-72 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 Gene3D G3DSA:3.40.50.300 353 601 1.5E-90 T 13-10-2018 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 Pfam PF00664 ABC transporter transmembrane region 37 309 1.9E-41 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_2423 d019ca9753d624f88f0ec2e0ccb8755b 605 SUPERFAMILY SSF52540 349 593 1.28E-90 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1258 cc43909f94295fc3689afb17e3d03483 393 SMART SM00487 22 229 6.4E-41 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1258 cc43909f94295fc3689afb17e3d03483 393 Gene3D G3DSA:3.40.50.300 225 377 4.5E-35 T 13-10-2018 Spica_1258 cc43909f94295fc3689afb17e3d03483 393 SMART SM00490 265 346 2.2E-21 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1258 cc43909f94295fc3689afb17e3d03483 393 Pfam PF00270 DEAD/DEAH box helicase 27 197 5.6E-36 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Spica_1258 cc43909f94295fc3689afb17e3d03483 393 Gene3D G3DSA:3.40.50.300 2 224 7.2E-54 T 13-10-2018 Spica_1258 cc43909f94295fc3689afb17e3d03483 393 Pfam PF00271 Helicase conserved C-terminal domain 238 346 6.8E-23 T 13-10-2018 IPR001650 Helicase, C-terminal Spica_1258 cc43909f94295fc3689afb17e3d03483 393 SUPERFAMILY SSF52540 79 366 2.19E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1258 cc43909f94295fc3689afb17e3d03483 393 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 159 167 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spica_1574 a06b7783b730998897b977d4b34c65e7 498 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 246 257 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_1574 a06b7783b730998897b977d4b34c65e7 498 SUPERFAMILY SSF54862 79 259 1.32E-17 T 13-10-2018 Spica_1574 a06b7783b730998897b977d4b34c65e7 498 Gene3D G3DSA:3.30.70.20 190 240 5.7E-6 T 13-10-2018 Spica_1574 a06b7783b730998897b977d4b34c65e7 498 Pfam PF12801 4Fe-4S binding domain 171 213 1.2E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1574 a06b7783b730998897b977d4b34c65e7 498 Pfam PF12801 4Fe-4S binding domain 70 111 3.7E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1574 a06b7783b730998897b977d4b34c65e7 498 Pfam PF12801 4Fe-4S binding domain 43 49 690.0 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1446 50cd89ef90abe78d9933491d761cb955 173 Pfam PF02357 Transcription termination factor nusG 2 94 2.1E-9 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_1446 50cd89ef90abe78d9933491d761cb955 173 Gene3D G3DSA:3.30.70.940 1 105 6.2E-10 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_1446 50cd89ef90abe78d9933491d761cb955 173 SUPERFAMILY SSF82679 1 105 5.1E-10 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Spica_1446 50cd89ef90abe78d9933491d761cb955 173 SUPERFAMILY SSF50104 115 170 1.35E-6 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Spica_1446 50cd89ef90abe78d9933491d761cb955 173 Gene3D G3DSA:2.30.30.30 111 170 3.3E-9 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Spica_0762 cd22269250d0662c356b5d641b5ef0f2 133 Gene3D G3DSA:3.30.1490.190 74 129 9.9E-19 T 13-10-2018 Spica_0762 cd22269250d0662c356b5d641b5ef0f2 133 Pfam PF01475 Ferric uptake regulator family 4 118 4.7E-25 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spica_0762 cd22269250d0662c356b5d641b5ef0f2 133 Gene3D G3DSA:1.10.10.10 2 72 5.3E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0762 cd22269250d0662c356b5d641b5ef0f2 133 SUPERFAMILY SSF46785 4 123 1.42E-30 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0721 4a20ec6826ae958bad731f622cabd56a 210 SUPERFAMILY SSF52218 1 188 2.17E-45 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0721 4a20ec6826ae958bad731f622cabd56a 210 Gene3D G3DSA:3.40.50.360 1 194 1.8E-38 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0721 4a20ec6826ae958bad731f622cabd56a 210 Pfam PF03358 NADPH-dependent FMN reductase 1 154 8.6E-33 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Spica_0324 00edb87219110a1282e5845cca0ffedd 264 Pfam PF00005 ABC transporter 19 170 3.0E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0324 00edb87219110a1282e5845cca0ffedd 264 Gene3D G3DSA:3.40.50.300 2 241 2.1E-51 T 13-10-2018 Spica_0324 00edb87219110a1282e5845cca0ffedd 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_0324 00edb87219110a1282e5845cca0ffedd 264 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 240 3.6E-95 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 Spica_0324 00edb87219110a1282e5845cca0ffedd 264 SUPERFAMILY SSF52540 4 228 2.27E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2567 af568bec1accc16e8cd526ee0000ff60 116 Gene3D G3DSA:3.30.70.330 10 115 1.7E-32 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_2567 af568bec1accc16e8cd526ee0000ff60 116 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 26 96 1.2E-24 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 Spica_2567 af568bec1accc16e8cd526ee0000ff60 116 SUPERFAMILY SSF54928 23 114 2.82E-33 T 13-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 Spica_2567 af568bec1accc16e8cd526ee0000ff60 116 SMART SM00360 25 98 2.1E-30 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 Gene3D G3DSA:3.30.420.40 84 200 2.2E-24 T 13-10-2018 Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 Gene3D G3DSA:1.10.10.10 10 78 1.3E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 Gene3D G3DSA:3.30.420.40 201 258 2.2E-24 T 13-10-2018 Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 SUPERFAMILY SSF53067 82 359 2.3E-22 T 13-10-2018 Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 SUPERFAMILY SSF46785 9 75 8.1E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 56 5.4E-5 T 13-10-2018 Spica_2471 2d979f2b17d1a4c41b6377a291b20fea 397 Pfam PF00480 ROK family 85 251 3.7E-8 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_1423 34e8aab55953f1242057b68e5df563bf 98 Pfam PF10719 Late competence development protein ComFB 14 95 1.0E-18 T 13-10-2018 IPR019657 Late competence development protein ComFB Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 436 478 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 Pfam PF00072 Response regulator receiver domain 4 111 1.5E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 Gene3D G3DSA:3.40.50.12740 3 168 2.0E-28 T 13-10-2018 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 SUPERFAMILY SSF46689 435 486 5.38E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 SUPERFAMILY SSF52172 1 122 1.38E-29 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 Gene3D G3DSA:1.10.10.60 432 487 1.9E-20 T 13-10-2018 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 SMART SM00342 399 482 1.4E-30 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 Pfam PF12833 Helix-turn-helix domain 406 484 3.8E-22 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 SMART SM00448 2 116 3.1E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 SUPERFAMILY SSF46689 385 433 9.86E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 Gene3D G3DSA:1.10.10.60 385 431 3.4E-16 T 13-10-2018 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 466 482 8.7E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_0033 c10f2c20c83a56cdd7115e09b02e95a6 496 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 451 466 8.7E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2421 9e2a8fe654e077bfa27e08d6c168d158 313 Gene3D G3DSA:1.10.3720.10 63 313 1.8E-61 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2421 9e2a8fe654e077bfa27e08d6c168d158 313 SUPERFAMILY SSF161098 67 298 6.67E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2421 9e2a8fe654e077bfa27e08d6c168d158 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 307 1.3E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1904 b7e2f9fcf668a605e2583a694a3bff3c 478 Gene3D G3DSA:1.20.1250.20 257 473 8.2E-15 T 13-10-2018 Spica_1904 b7e2f9fcf668a605e2583a694a3bff3c 478 Gene3D G3DSA:1.20.1250.20 22 240 3.2E-7 T 13-10-2018 Spica_1904 b7e2f9fcf668a605e2583a694a3bff3c 478 SUPERFAMILY SSF103473 71 472 1.07E-28 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_1904 b7e2f9fcf668a605e2583a694a3bff3c 478 Pfam PF13347 MFS/sugar transport protein 24 461 3.4E-44 T 13-10-2018 Spica_2280 2db2046c6e81bbbb33524307fd02d92d 110 Gene3D G3DSA:1.10.10.10 11 105 1.8E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2280 2db2046c6e81bbbb33524307fd02d92d 110 Pfam PF13601 Winged helix DNA-binding domain 22 101 2.6E-27 T 13-10-2018 IPR027395 Winged helix DNA-binding domain Spica_2280 2db2046c6e81bbbb33524307fd02d92d 110 SUPERFAMILY SSF46785 16 104 1.6E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2280 2db2046c6e81bbbb33524307fd02d92d 110 SMART SM00418 16 106 0.002 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_0260 0231ff626dd0d39bc766943c0d9fb0ef 264 Gene3D G3DSA:3.20.20.60 103 188 1.8E-7 T 13-10-2018 Spica_0260 0231ff626dd0d39bc766943c0d9fb0ef 264 Gene3D G3DSA:3.20.20.60 24 102 1.2E-5 T 13-10-2018 Spica_0260 0231ff626dd0d39bc766943c0d9fb0ef 264 SUPERFAMILY SSF51621 36 167 1.43E-15 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Spica_0260 0231ff626dd0d39bc766943c0d9fb0ef 264 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 50 142 2.1E-8 T 13-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Spica_0126 26de97077ddc8e9fa5a3f285457930c7 316 Gene3D G3DSA:3.40.50.2300 38 295 4.7E-93 T 13-10-2018 Spica_0126 26de97077ddc8e9fa5a3f285457930c7 316 SUPERFAMILY SSF53822 20 310 1.69E-79 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0126 26de97077ddc8e9fa5a3f285457930c7 316 Gene3D G3DSA:3.40.50.2300 131 306 4.7E-93 T 13-10-2018 Spica_0126 26de97077ddc8e9fa5a3f285457930c7 316 Pfam PF13407 Periplasmic binding protein domain 36 289 9.2E-58 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0117 ef2ac96ce44b3f3da926f5634123ab32 292 Pfam PF02698 DUF218 domain 93 282 1.5E-30 T 13-10-2018 IPR003848 Domain of unknown function DUF218 Spica_2397 97616ef14cb8cf35f2b97a204e5541a8 74 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 8 62 2.2E-17 T 13-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Spica_2397 97616ef14cb8cf35f2b97a204e5541a8 74 Gene3D G3DSA:3.30.920.30 5 64 4.5E-18 T 13-10-2018 IPR038570 HicA superfamily Spica_2397 97616ef14cb8cf35f2b97a204e5541a8 74 SUPERFAMILY SSF54786 5 67 1.26E-16 T 13-10-2018 Spica_2865 9630e7f68d62e3ddcb1828e45d6e042a 113 PIRSF PIRSF033490 1 112 8.9E-32 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Spica_2865 9630e7f68d62e3ddcb1828e45d6e042a 113 SUPERFAMILY SSF50118 1 112 1.14E-29 T 13-10-2018 Spica_2865 9630e7f68d62e3ddcb1828e45d6e042a 113 Gene3D G3DSA:2.30.30.110 1 112 4.9E-34 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spica_2865 9630e7f68d62e3ddcb1828e45d6e042a 113 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 109 1.5E-21 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Spica_1795 5f61e8e4c7e279336eee7325d7c28284 404 ProSitePatterns PS01007 Transposases, Mutator family, signature. 235 259 - T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Spica_1795 5f61e8e4c7e279336eee7325d7c28284 404 Pfam PF00872 Transposase, Mutator family 16 380 2.6E-120 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Spica_0109 853960bd15443a6ed9df1c0fc973169f 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 51 9.9E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Spica_0109 853960bd15443a6ed9df1c0fc973169f 76 Gene3D G3DSA:2.10.260.10 1 76 8.1E-28 T 13-10-2018 Spica_0109 853960bd15443a6ed9df1c0fc973169f 76 SUPERFAMILY SSF89447 3 66 7.32E-11 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SUPERFAMILY SSF48452 163 362 1.52E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SUPERFAMILY SSF48452 441 569 1.38E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 Gene3D G3DSA:1.25.40.10 437 578 2.9E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 Pfam PF14559 Tetratricopeptide repeat 263 324 9.6E-7 T 13-10-2018 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SMART SM00028 213 246 240.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SMART SM00028 247 280 18.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SMART SM00028 179 212 6.6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 SMART SM00028 532 565 19.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1838 5a1cfb1e2999ac4e8d9f27682c9bbd89 580 Gene3D G3DSA:1.25.40.10 68 388 1.1E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2482 c98c2ecc03802ddddf156554967d86c7 305 SUPERFAMILY SSF54862 174 241 1.36E-9 T 13-10-2018 Spica_2482 c98c2ecc03802ddddf156554967d86c7 305 Pfam PF13484 4Fe-4S double cluster binding domain 178 241 1.1E-8 T 13-10-2018 Spica_2482 c98c2ecc03802ddddf156554967d86c7 305 Gene3D G3DSA:3.30.70.20 182 248 2.2E-6 T 13-10-2018 Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 Pfam PF00460 Flagella basal body rod protein 5 35 3.0E-12 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 185 260 5.7E-23 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 SUPERFAMILY SSF117143 94 224 8.89E-36 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 2.9E-47 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 150 245 4.8E-30 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 243 8.3E-54 T 13-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 Spica_1473 8128962ba2e2a2f2f5d7c60224238179 264 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 2.0E-110 T 13-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 Spica_2533 8cb008b741aec9173a5ddc1d2dd5fcb5 159 SUPERFAMILY SSF103039 2 145 3.79E-24 T 13-10-2018 IPR028976 CheC-like superfamily Spica_2533 8cb008b741aec9173a5ddc1d2dd5fcb5 159 Gene3D G3DSA:3.40.1550.10 2 153 6.9E-36 T 13-10-2018 IPR028976 CheC-like superfamily Spica_2533 8cb008b741aec9173a5ddc1d2dd5fcb5 159 Pfam PF13690 Chemotaxis phosphatase CheX 42 137 5.3E-23 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain Spica_0068 b22164df1f24292c99172a13586e377a 303 Gene3D G3DSA:3.40.1190.20 1 296 3.6E-46 T 13-10-2018 IPR029056 Ribokinase-like Spica_0068 b22164df1f24292c99172a13586e377a 303 Pfam PF00294 pfkB family carbohydrate kinase 34 283 1.4E-29 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_0068 b22164df1f24292c99172a13586e377a 303 SUPERFAMILY SSF53613 1 284 2.03E-41 T 13-10-2018 IPR029056 Ribokinase-like Spica_1015 6a91b61dd90a78712433d5be21c56d8f 284 Pfam PF00849 RNA pseudouridylate synthase 33 191 1.0E-27 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1015 6a91b61dd90a78712433d5be21c56d8f 284 SUPERFAMILY SSF55120 20 226 1.42E-38 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1015 6a91b61dd90a78712433d5be21c56d8f 284 Gene3D G3DSA:3.30.2350.10 17 237 4.5E-43 T 13-10-2018 Spica_2264 ce0aa41a3e40cfead65fac419d15bb9e 116 PIRSF PIRSF033199 1 116 5.2E-50 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 Spica_2264 ce0aa41a3e40cfead65fac419d15bb9e 116 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 9.2E-49 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 Spica_2264 ce0aa41a3e40cfead65fac419d15bb9e 116 Gene3D G3DSA:1.10.8.290 1 116 2.1E-50 T 13-10-2018 IPR023204 SP1917 domain superfamily Spica_0787 554a610080029e49a0759d79c152376d 401 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 300 394 4.2E-13 T 13-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain Spica_0787 554a610080029e49a0759d79c152376d 401 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 90 182 1.4E-7 T 13-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain Spica_0787 554a610080029e49a0759d79c152376d 401 Gene3D G3DSA:1.10.260.150 61 284 7.2E-17 T 13-10-2018 Spica_1711 08198d52a0ea081aa24e7b18abd0f8d2 146 SUPERFAMILY SSF50475 7 127 9.54E-20 T 13-10-2018 Spica_1711 08198d52a0ea081aa24e7b18abd0f8d2 146 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 8 128 6.7E-13 T 13-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain Spica_1711 08198d52a0ea081aa24e7b18abd0f8d2 146 Gene3D G3DSA:2.30.110.10 2 134 3.6E-28 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 Pfam PF12848 ABC transporter 234 310 2.6E-11 T 13-10-2018 IPR032781 ABC-transporter extension domain Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 SMART SM00382 352 523 2.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 SMART SM00382 35 240 1.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 SUPERFAMILY SSF52540 13 246 8.12E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 Gene3D G3DSA:3.40.50.300 290 557 4.3E-69 T 13-10-2018 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 SUPERFAMILY SSF52540 314 537 3.55E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 Pfam PF00005 ABC transporter 344 478 2.5E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 Gene3D G3DSA:3.40.50.300 8 289 9.1E-76 T 13-10-2018 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 8 557 1.2E-275 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 Spica_1095 cd398c14514e5bbb0a24ea724094674e 559 Pfam PF00005 ABC transporter 26 195 1.5E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_0486 0800944244f82adb87066added65c8ae 276 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 238 4.6E-61 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spica_0486 0800944244f82adb87066added65c8ae 276 Gene3D G3DSA:3.40.1280.10 1 189 3.3E-66 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0486 0800944244f82adb87066added65c8ae 276 SUPERFAMILY SSF75217 2 245 2.3E-89 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0486 0800944244f82adb87066added65c8ae 276 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 276 97.507 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spica_0486 0800944244f82adb87066added65c8ae 276 PIRSF PIRSF000386 1 271 2.8E-90 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spica_0486 0800944244f82adb87066added65c8ae 276 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 243 3.0E-90 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spica_0486 0800944244f82adb87066added65c8ae 276 Gene3D G3DSA:1.10.1270.20 190 267 2.0E-28 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Spica_2831 8519d897919af5b3c64099699b607560 325 SUPERFAMILY SSF51735 104 288 9.89E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2831 8519d897919af5b3c64099699b607560 325 Gene3D G3DSA:3.40.50.720 102 293 1.8E-90 T 13-10-2018 Spica_2831 8519d897919af5b3c64099699b607560 325 Gene3D G3DSA:3.40.50.720 25 325 1.8E-90 T 13-10-2018 Spica_2831 8519d897919af5b3c64099699b607560 325 SUPERFAMILY SSF52283 49 132 9.35E-7 T 13-10-2018 Spica_2831 8519d897919af5b3c64099699b607560 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 287 3.9E-49 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spica_2200 dd5c9e51ee837a063fae0a6d1ead2cd2 231 SUPERFAMILY SSF52058 56 214 4.25E-13 T 13-10-2018 Spica_2200 dd5c9e51ee837a063fae0a6d1ead2cd2 231 Gene3D G3DSA:3.80.10.10 30 221 8.2E-15 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Spica_2200 dd5c9e51ee837a063fae0a6d1ead2cd2 231 Pfam PF01827 FTH domain 56 136 7.0E-5 T 13-10-2018 IPR002900 Domain of unknown function DUF38, Caenorhabditis species Spica_2306 784d469709e4418cb722591c72e220f1 345 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 10 299 9.0E-56 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Spica_2306 784d469709e4418cb722591c72e220f1 345 Pfam PF03186 CobD/Cbib protein 11 323 1.3E-85 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Spica_2306 784d469709e4418cb722591c72e220f1 345 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 345 78.785 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 Spica_1889 139734667ada3cbeee731d8ec6980a83 420 Pfam PF00149 Calcineurin-like phosphoesterase 1 121 5.0E-10 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_1889 139734667ada3cbeee731d8ec6980a83 420 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 296 395 4.8E-7 T 13-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain Spica_1889 139734667ada3cbeee731d8ec6980a83 420 SUPERFAMILY SSF56300 1 341 7.44E-49 T 13-10-2018 Spica_1889 139734667ada3cbeee731d8ec6980a83 420 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 269 1.2E-53 T 13-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 Spica_1889 139734667ada3cbeee731d8ec6980a83 420 Gene3D G3DSA:3.60.21.10 1 293 2.1E-73 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_1376 010b524a852256e727c42a4026510784 181 Pfam PF04079 Segregation and condensation complex subunit ScpB 11 169 5.7E-55 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spica_1376 010b524a852256e727c42a4026510784 181 PIRSF PIRSF019345 1 178 6.0E-53 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spica_1376 010b524a852256e727c42a4026510784 181 SUPERFAMILY SSF46785 87 160 3.27E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1376 010b524a852256e727c42a4026510784 181 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 10 177 6.4E-40 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Spica_1376 010b524a852256e727c42a4026510784 181 SUPERFAMILY SSF46785 4 80 1.86E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1376 010b524a852256e727c42a4026510784 181 Gene3D G3DSA:1.10.10.10 3 85 1.2E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1376 010b524a852256e727c42a4026510784 181 Gene3D G3DSA:1.10.10.10 86 178 2.3E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0161 824721b280d399e2f6ad9c3dcf61772e 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 97 4.2E-12 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Spica_0161 824721b280d399e2f6ad9c3dcf61772e 107 Gene3D G3DSA:3.10.20.30 9 107 1.0E-20 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Spica_0161 824721b280d399e2f6ad9c3dcf61772e 107 SUPERFAMILY SSF54292 11 105 4.59E-19 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Spica_1165 0b09ce4749b030a3685acad04ae92bed 169 Pfam PF05154 TM2 domain 3 51 1.3E-10 T 13-10-2018 IPR007829 TM2 domain Spica_1165 0b09ce4749b030a3685acad04ae92bed 169 SUPERFAMILY SSF46785 99 150 3.88E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2165 51910cc0407f7c24272735f4dd123f81 432 SUPERFAMILY SSF103473 7 405 2.49E-61 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_2165 51910cc0407f7c24272735f4dd123f81 432 Gene3D G3DSA:1.20.1250.20 3 407 7.6E-60 T 13-10-2018 Spica_2165 51910cc0407f7c24272735f4dd123f81 432 Pfam PF07690 Major Facilitator Superfamily 14 320 3.6E-41 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_2650 b137232b60de256954b3c8238965d9f3 530 SUPERFAMILY SSF51905 99 526 7.16E-36 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2650 b137232b60de256954b3c8238965d9f3 530 PIRSF PIRSF038984 2 530 5.9E-198 T 13-10-2018 IPR028348 FAD dependent protein Spica_2650 b137232b60de256954b3c8238965d9f3 530 Gene3D G3DSA:3.30.70.2700 1 76 1.1E-16 T 13-10-2018 Spica_2650 b137232b60de256954b3c8238965d9f3 530 Pfam PF01266 FAD dependent oxidoreductase 209 340 3.6E-7 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Spica_2650 b137232b60de256954b3c8238965d9f3 530 Gene3D G3DSA:3.50.50.60 472 529 6.3E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2650 b137232b60de256954b3c8238965d9f3 530 Gene3D G3DSA:3.50.50.60 88 303 1.1E-74 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2541 de48c038614dfff298ca934b2183c0d0 260 Pfam PF12872 OST-HTH/LOTUS domain 177 244 1.3E-17 T 13-10-2018 IPR025605 OST-HTH/LOTUS domain Spica_2541 de48c038614dfff298ca934b2183c0d0 260 Gene3D G3DSA:1.10.10.1880 184 256 4.9E-24 T 13-10-2018 Spica_2541 de48c038614dfff298ca934b2183c0d0 260 Pfam PF01936 NYN domain 17 150 5.9E-31 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type Spica_2541 de48c038614dfff298ca934b2183c0d0 260 Gene3D G3DSA:3.40.50.1010 8 154 4.9E-13 T 13-10-2018 Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 SMART SM00257 274 321 5.1E-5 T 13-10-2018 IPR018392 LysM domain Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 Gene3D G3DSA:2.60.34.10 1 110 2.9E-20 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 SUPERFAMILY SSF100920 3 99 3.92E-18 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 Pfam PF01476 LysM domain 275 321 2.0E-8 T 13-10-2018 IPR018392 LysM domain Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 Gene3D G3DSA:3.10.350.10 274 320 1.5E-10 T 13-10-2018 IPR036779 LysM domain superfamily Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 SUPERFAMILY SSF54106 275 321 7.06E-6 T 13-10-2018 Spica_0363 f54ca43bd22a96eac6a26b4ee5e5cb88 324 Pfam PF00012 Hsp70 protein 4 81 2.8E-9 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Spica_0497 793660e26a7fc888ccea5e1c4960b845 404 Gene3D G3DSA:3.40.50.11400 31 146 5.6E-77 T 13-10-2018 Spica_0497 793660e26a7fc888ccea5e1c4960b845 404 Pfam PF12683 Protein of unknown function (DUF3798) 31 306 1.3E-128 T 13-10-2018 IPR024258 Protein of unknown function DUF3798 Spica_0497 793660e26a7fc888ccea5e1c4960b845 404 SUPERFAMILY SSF53822 75 243 9.42E-6 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0497 793660e26a7fc888ccea5e1c4960b845 404 Gene3D G3DSA:3.40.50.11390 147 304 5.6E-77 T 13-10-2018 Spica_2287 d4fdd54ecbf9b58b59ba55a85dcc9478 274 SUPERFAMILY SSF161098 2 274 1.31E-64 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2287 d4fdd54ecbf9b58b59ba55a85dcc9478 274 Gene3D G3DSA:1.10.3720.10 1 265 1.6E-54 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2287 d4fdd54ecbf9b58b59ba55a85dcc9478 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 260 1.0E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0330 1567def8dbc39de8c1f6f2668c5c93f4 243 Pfam PF02592 Putative vitamin uptake transporter 51 216 8.5E-44 T 13-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Spica_0330 1567def8dbc39de8c1f6f2668c5c93f4 243 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 16 222 9.6E-32 T 13-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Spica_0330 1567def8dbc39de8c1f6f2668c5c93f4 243 Hamap MF_02088 Probable queuosine precursor transporter. 7 228 16.575 T 13-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Spica_0756 2a47919abe14f51a7e327518d294073f 372 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 42 351 4.3E-59 T 13-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 Spica_0756 2a47919abe14f51a7e327518d294073f 372 Gene3D G3DSA:3.40.50.2300 41 314 1.2E-91 T 13-10-2018 Spica_0756 2a47919abe14f51a7e327518d294073f 372 SUPERFAMILY SSF53822 76 311 5.3E-14 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0756 2a47919abe14f51a7e327518d294073f 372 Gene3D G3DSA:3.40.50.2300 147 347 1.2E-91 T 13-10-2018 Spica_0154 8745871acd983c7642d386b332bb2fe5 287 Pfam PF01988 VIT family 136 196 2.2E-9 T 13-10-2018 IPR008217 Ccc1 family Spica_0154 8745871acd983c7642d386b332bb2fe5 287 SUPERFAMILY SSF47240 2 127 2.82E-12 T 13-10-2018 IPR009078 Ferritin-like superfamily Spica_0154 8745871acd983c7642d386b332bb2fe5 287 Pfam PF02915 Rubrerythrin 11 125 8.6E-5 T 13-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 SUPERFAMILY SSF109998 35 201 5.1E-21 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 Gene3D G3DSA:3.10.50.40 179 285 4.5E-38 T 13-10-2018 Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 Gene3D G3DSA:1.10.4030.30 36 289 4.5E-38 T 13-10-2018 Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 SUPERFAMILY SSF54534 176 284 3.34E-13 T 13-10-2018 Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 Pfam PF13145 PPIC-type PPIASE domain 159 295 1.9E-16 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Spica_0923 3d64aa49b107bc84132e12e752ea0a93 348 Pfam PF13624 SurA N-terminal domain 36 144 1.8E-8 T 13-10-2018 Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 SUPERFAMILY SSF81296 5 93 3.5E-15 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 Pfam PF02927 Cellulase N-terminal ig-like domain 9 84 5.6E-14 T 13-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 Gene3D G3DSA:2.60.40.10 4 92 1.6E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 SUPERFAMILY SSF48208 92 579 2.33E-116 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 Gene3D G3DSA:1.50.10.10 94 581 1.4E-174 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 550 568 - T 13-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_2709 c08e45549e6b08c0effcaf1b5d807f45 589 Pfam PF00759 Glycosyl hydrolase family 9 96 573 6.6E-102 T 13-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Spica_2606 11e5dec8974e92db09435beb42ffcf20 278 Pfam PF01061 ABC-2 type transporter 4 209 5.1E-34 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 Spica_2606 11e5dec8974e92db09435beb42ffcf20 278 PIRSF PIRSF006648 1 263 4.4E-43 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Spica_2606 11e5dec8974e92db09435beb42ffcf20 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 131 155 1.6E-10 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Spica_2606 11e5dec8974e92db09435beb42ffcf20 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 50 72 1.6E-10 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Spica_2606 11e5dec8974e92db09435beb42ffcf20 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 168 187 1.6E-10 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 45 213 6.5E-68 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 Gene3D G3DSA:2.30.210.20 15 69 1.9E-18 T 13-10-2018 Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 SUPERFAMILY SSF55729 16 231 2.44E-81 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 Gene3D G3DSA:3.40.630.70 70 239 5.1E-62 T 13-10-2018 Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 47 230 4.8E-59 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Spica_2014 8d24a89e2487e28b701e078b8e2ed4ff 251 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 251 80.046 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Spica_1289 5c3608882471c230547cbcd55f549d8f 323 Pfam PF14238 Domain of unknown function (DUF4340) 75 255 2.5E-12 T 13-10-2018 IPR025641 Domain of unknown function DUF4340 Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Gene3D G3DSA:2.60.40.4070 803 880 1.6E-7 T 13-10-2018 Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Gene3D G3DSA:3.30.1330.60 1186 1340 2.6E-22 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Pfam PF13585 C-terminal domain of CHU protein family 469 547 2.6E-6 T 13-10-2018 Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 SUPERFAMILY SSF103088 1243 1338 9.81E-20 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Pfam PF13860 FlgD Ig-like domain 920 975 2.4E-6 T 13-10-2018 IPR025965 FlgD Ig-like domain Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Pfam PF00691 OmpA family 1247 1327 2.9E-11 T 13-10-2018 IPR006665 OmpA-like domain Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Gene3D G3DSA:2.60.40.4070 718 775 2.4E-6 T 13-10-2018 Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Gene3D G3DSA:2.60.40.4070 909 984 2.0E-9 T 13-10-2018 Spica_2364 d33fcc7e0fc50282b4003259fc4f514a 1340 Gene3D G3DSA:2.60.40.4070 476 553 6.0E-10 T 13-10-2018 Spica_1103 31b51d3968b9d06dc6c0708f2e4cd2d4 886 SUPERFAMILY SSF48452 516 698 1.14E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1103 31b51d3968b9d06dc6c0708f2e4cd2d4 886 Gene3D G3DSA:1.25.40.10 499 716 2.2E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1103 31b51d3968b9d06dc6c0708f2e4cd2d4 886 SMART SM00028 638 671 12.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1103 31b51d3968b9d06dc6c0708f2e4cd2d4 886 SMART SM00028 598 631 8.4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1103 31b51d3968b9d06dc6c0708f2e4cd2d4 886 SMART SM00028 558 591 190.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0732 25690c9a04ac69ff11c5560876e92275 438 Pfam PF02321 Outer membrane efflux protein 39 219 9.0E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_0732 25690c9a04ac69ff11c5560876e92275 438 Pfam PF02321 Outer membrane efflux protein 258 430 1.3E-13 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_0732 25690c9a04ac69ff11c5560876e92275 438 Gene3D G3DSA:1.20.1600.10 37 433 3.0E-45 T 13-10-2018 Spica_0732 25690c9a04ac69ff11c5560876e92275 438 SUPERFAMILY SSF56954 2 432 2.62E-46 T 13-10-2018 Spica_1468 8aa7a4b584e7509471bdf6382cec0d9b 236 Gene3D G3DSA:1.20.120.1760 15 231 1.4E-25 T 13-10-2018 Spica_1468 8aa7a4b584e7509471bdf6382cec0d9b 236 Pfam PF01066 CDP-alcohol phosphatidyltransferase 45 114 3.9E-8 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spica_1210 39d813aba133136e07017b681e9485b0 370 SUPERFAMILY SSF53383 9 368 6.49E-111 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1210 39d813aba133136e07017b681e9485b0 370 PIRSF PIRSF000524 4 370 5.8E-120 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Spica_1210 39d813aba133136e07017b681e9485b0 370 Gene3D G3DSA:3.90.1150.10 9 367 8.7E-146 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1210 39d813aba133136e07017b681e9485b0 370 Gene3D G3DSA:3.40.640.10 21 266 8.7E-146 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1210 39d813aba133136e07017b681e9485b0 370 Pfam PF00266 Aminotransferase class-V 31 360 1.1E-46 T 13-10-2018 IPR000192 Aminotransferase class V domain Spica_1932 847c21b8575a36b96fd0bece85503831 187 SUPERFAMILY SSF52980 12 167 9.65E-33 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1932 847c21b8575a36b96fd0bece85503831 187 Pfam PF05685 Putative restriction endonuclease 24 183 1.5E-27 T 13-10-2018 IPR008538 Domain of unknown function DUF820 Spica_1932 847c21b8575a36b96fd0bece85503831 187 Gene3D G3DSA:3.90.1570.10 9 179 1.5E-27 T 13-10-2018 Spica_0703 e56bc47c4c934af93c4fdc94736e007b 320 Pfam PF03595 Voltage-dependent anion channel 9 306 1.2E-56 T 13-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 Spica_0703 e56bc47c4c934af93c4fdc94736e007b 320 Gene3D G3DSA:1.50.10.150 4 317 1.9E-87 T 13-10-2018 IPR038665 Voltage-dependent anion channel superfamily Spica_1007 1ed6e6f40706f3a572dc0d15336f3eec 468 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 12 149 7.3E-21 T 13-10-2018 Spica_1007 1ed6e6f40706f3a572dc0d15336f3eec 468 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 171 339 1.0E-29 T 13-10-2018 Spica_1007 1ed6e6f40706f3a572dc0d15336f3eec 468 Gene3D G3DSA:2.30.310.10 4 152 2.6E-21 T 13-10-2018 Spica_1007 1ed6e6f40706f3a572dc0d15336f3eec 468 Pfam PF05670 Domain of unknown function (DUF814) 347 432 9.3E-20 T 13-10-2018 IPR008532 Domain of unknown function DUF814 Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 102 1.3E-23 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 SUPERFAMILY SSF82607 7 99 1.96E-25 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 PIRSF PIRSF004555 1 105 9.3E-31 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 Gene3D G3DSA:3.30.1310.10 1 105 3.0E-31 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 Pfam PF02575 YbaB/EbfC DNA-binding family 8 96 1.0E-26 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spica_0202 e97a99f5f6964c7ffbbc80c4475644fe 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 95 18.802 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spica_2180 48af28675312b4a3d78960207e9eec0c 262 Gene3D G3DSA:3.40.1210.10 4 250 3.3E-74 T 13-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Spica_2180 48af28675312b4a3d78960207e9eec0c 262 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 10 239 1.4E-57 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Spica_2180 48af28675312b4a3d78960207e9eec0c 262 SUPERFAMILY SSF64167 10 245 9.29E-65 T 13-10-2018 Spica_2180 48af28675312b4a3d78960207e9eec0c 262 Pfam PF01975 Survival protein SurE 12 193 2.6E-53 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Spica_2180 48af28675312b4a3d78960207e9eec0c 262 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 10 260 30.598 T 13-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Spica_0020 0c49e8e4d8a62b397ed6ad0ae2512bd9 459 Gene3D G3DSA:3.40.50.1820 144 371 2.7E-8 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_0020 0c49e8e4d8a62b397ed6ad0ae2512bd9 459 SUPERFAMILY SSF53474 123 374 4.27E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2305 134e090ba94e63b6bf6eb5feeb3b42fb 402 Pfam PF07690 Major Facilitator Superfamily 44 360 1.1E-26 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_2305 134e090ba94e63b6bf6eb5feeb3b42fb 402 Gene3D G3DSA:1.20.1250.20 13 213 8.0E-14 T 13-10-2018 Spica_2305 134e090ba94e63b6bf6eb5feeb3b42fb 402 Gene3D G3DSA:1.20.1250.20 221 398 4.6E-15 T 13-10-2018 Spica_2305 134e090ba94e63b6bf6eb5feeb3b42fb 402 SUPERFAMILY SSF103473 26 395 2.22E-37 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_1587 2bd382d7c9c47180e946eebcd5b0a02e 485 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 234 405 1.2E-16 T 13-10-2018 IPR004477 ComEC/Rec2-related protein Spica_1587 2bd382d7c9c47180e946eebcd5b0a02e 485 Pfam PF03772 Competence protein 212 470 2.1E-36 T 13-10-2018 IPR004477 ComEC/Rec2-related protein Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 Gene3D G3DSA:3.40.50.1360 1 264 2.9E-114 T 13-10-2018 Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 234 3.3E-21 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 8.7E-121 T 13-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 SUPERFAMILY SSF100950 1 261 4.28E-103 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 39.927 T 13-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 Spica_2473 d66eb4d6d3e1c22052474e3ba6ecf0af 266 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 13-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 Spica_0854 64581317cd88a94acd6f6ad771419346 129 Pfam PF02195 ParB-like nuclease domain 2 84 1.1E-15 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Spica_0854 64581317cd88a94acd6f6ad771419346 129 SMART SM00470 1 85 3.0E-17 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Spica_0854 64581317cd88a94acd6f6ad771419346 129 SUPERFAMILY SSF110849 3 106 1.05E-17 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Spica_0854 64581317cd88a94acd6f6ad771419346 129 Gene3D G3DSA:3.90.1530.30 11 69 1.3E-10 T 13-10-2018 Spica_1908 b21b0a39d323cced35bdd93bf25c5f48 301 Gene3D G3DSA:1.10.3720.10 51 297 1.0E-59 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1908 b21b0a39d323cced35bdd93bf25c5f48 301 SUPERFAMILY SSF161098 53 285 1.31E-50 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1908 b21b0a39d323cced35bdd93bf25c5f48 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 294 7.8E-12 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1908 b21b0a39d323cced35bdd93bf25c5f48 301 SUPERFAMILY SSF160964 14 45 1.01E-7 T 13-10-2018 Spica_2122 efb1b0c374d1b9f3c305077a31aa449c 422 SUPERFAMILY SSF53850 31 419 4.5E-42 T 13-10-2018 Spica_2122 efb1b0c374d1b9f3c305077a31aa449c 422 Gene3D G3DSA:3.40.190.10 60 360 4.9E-49 T 13-10-2018 Spica_2122 efb1b0c374d1b9f3c305077a31aa449c 422 Pfam PF13416 Bacterial extracellular solute-binding protein 52 359 3.8E-33 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2122 efb1b0c374d1b9f3c305077a31aa449c 422 Gene3D G3DSA:3.40.190.10 137 409 4.9E-49 T 13-10-2018 Spica_1091 2dd3d1c3e586ceda757e9b4a03156069 410 Gene3D G3DSA:2.40.10.220 293 396 5.2E-7 T 13-10-2018 Spica_1091 2dd3d1c3e586ceda757e9b4a03156069 410 Pfam PF07238 PilZ domain 309 394 3.8E-10 T 13-10-2018 IPR009875 PilZ domain GO:0035438 Spica_1091 2dd3d1c3e586ceda757e9b4a03156069 410 SUPERFAMILY SSF141371 312 393 1.96E-5 T 13-10-2018 Spica_1057 f213387372f55095f5c248a4d4170f3e 283 Gene3D G3DSA:1.10.3720.10 7 270 2.5E-52 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1057 f213387372f55095f5c248a4d4170f3e 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 270 4.9E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1057 f213387372f55095f5c248a4d4170f3e 283 SUPERFAMILY SSF161098 14 282 1.44E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0731 a490e56e05e7c15976941889ff23bae7 305 SUPERFAMILY SSF111369 61 223 4.18E-10 T 13-10-2018 Spica_0731 a490e56e05e7c15976941889ff23bae7 305 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 114 297 7.4E-38 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Spica_0731 a490e56e05e7c15976941889ff23bae7 305 Gene3D G3DSA:2.40.30.170 53 229 9.9E-81 T 13-10-2018 Spica_0731 a490e56e05e7c15976941889ff23bae7 305 Gene3D G3DSA:2.40.420.20 50 301 9.9E-81 T 13-10-2018 Spica_0731 a490e56e05e7c15976941889ff23bae7 305 Gene3D G3DSA:2.40.50.100 71 142 9.9E-81 T 13-10-2018 Spica_0731 a490e56e05e7c15976941889ff23bae7 305 Pfam PF13533 Biotin-lipoyl like 70 104 4.1E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Spica_0731 a490e56e05e7c15976941889ff23bae7 305 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 111 218 8.8E-19 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Spica_0718 f7c38e9b42093d7cd3dca129d4c7912e 305 SUPERFAMILY SSF46785 8 231 6.4E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0718 f7c38e9b42093d7cd3dca129d4c7912e 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 22 64 5.6E-8 T 13-10-2018 Spica_0718 f7c38e9b42093d7cd3dca129d4c7912e 305 SMART SM00418 12 95 0.0023 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Spica_0718 f7c38e9b42093d7cd3dca129d4c7912e 305 Gene3D G3DSA:1.10.10.10 2 95 4.8E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0542 5ed2521a34ef962d01b84d59cee765a0 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 316 7.5E-16 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1951 aace8e32abfad67de79923903695fb8b 224 Pfam PF00027 Cyclic nucleotide-binding domain 38 123 5.5E-10 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_1951 aace8e32abfad67de79923903695fb8b 224 SMART SM00419 166 214 1.9E-8 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Spica_1951 aace8e32abfad67de79923903695fb8b 224 SUPERFAMILY SSF46785 153 219 2.51E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_1951 aace8e32abfad67de79923903695fb8b 224 Pfam PF13545 Crp-like helix-turn-helix domain 156 217 3.7E-12 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Spica_1951 aace8e32abfad67de79923903695fb8b 224 Gene3D G3DSA:2.60.120.1460 4 218 1.8E-53 T 13-10-2018 Spica_1951 aace8e32abfad67de79923903695fb8b 224 SUPERFAMILY SSF51206 13 144 3.8E-20 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_0726 ed546ea857e40ab78257ec3c5fbe8bfa 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 286 6.3E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0726 ed546ea857e40ab78257ec3c5fbe8bfa 296 SUPERFAMILY SSF161098 55 286 3.92E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0726 ed546ea857e40ab78257ec3c5fbe8bfa 296 Gene3D G3DSA:1.10.3720.10 51 294 6.0E-66 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 427 6.9E-144 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Gene3D G3DSA:1.20.5.100 208 238 2.0E-18 T 13-10-2018 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Gene3D G3DSA:3.40.50.720 1 204 6.3E-82 T 13-10-2018 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Gene3D G3DSA:3.40.50.720 239 446 5.2E-76 T 13-10-2018 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 SUPERFAMILY SSF48179 208 306 4.29E-33 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 PIRSF PIRSF000124 2 446 7.8E-147 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 PIRSF PIRSF500134 2 446 6.6E-184 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 326 430 2.8E-33 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 208 300 5.0E-37 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 SUPERFAMILY SSF51735 3 195 3.3E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 190 5.3E-69 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 SMART SM00984 326 431 3.9E-45 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Spica_1455 7e9d54ea65bc79d215ff1362f39b6c02 446 SUPERFAMILY SSF52413 318 441 4.97E-38 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 Spica_1881 cab4a81a8d12f1aaa5056ca1d096d658 189 SUPERFAMILY SSF52980 14 188 1.34E-34 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_1881 cab4a81a8d12f1aaa5056ca1d096d658 189 Pfam PF05685 Putative restriction endonuclease 23 188 2.3E-31 T 13-10-2018 IPR008538 Domain of unknown function DUF820 Spica_1881 cab4a81a8d12f1aaa5056ca1d096d658 189 Gene3D G3DSA:3.90.1570.10 10 187 2.5E-28 T 13-10-2018 Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 SUPERFAMILY SSF117892 171 228 6.02E-6 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 PIRSF PIRSF005651 1 327 7.8E-94 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 Gene3D G3DSA:3.30.479.30 51 153 2.7E-10 T 13-10-2018 Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 SUPERFAMILY SSF117892 55 140 4.45E-13 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 Pfam PF01145 SPFH domain / Band 7 family 26 144 1.0E-15 T 13-10-2018 IPR001107 Band 7 domain Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 Pfam PF01145 SPFH domain / Band 7 family 164 233 1.1E-5 T 13-10-2018 IPR001107 Band 7 domain Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 TIGRFAM TIGR01932 hflC: HflC protein 8 322 6.9E-97 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 Spica_1195 9afb4f5b451f49a13b517aa039a8fbf5 327 SMART SM00244 22 224 1.4E-23 T 13-10-2018 IPR001107 Band 7 domain Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 SMART SM00864 17 209 1.2E-110 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 Pfam PF12327 FtsZ family, C-terminal domain 226 320 2.0E-27 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 13 389 37.123 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 Gene3D G3DSA:3.40.50.1440 12 224 2.4E-77 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 SUPERFAMILY SSF55307 208 323 1.35E-37 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 18 177 7.2E-41 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 ProSitePatterns PS01135 FtsZ protein signature 2. 101 122 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 Gene3D G3DSA:3.30.1330.20 225 337 2.9E-35 T 13-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 335 5.0E-130 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 ProSitePatterns PS01134 FtsZ protein signature 1. 48 82 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 SMART SM00865 211 329 5.9E-45 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 PRINTS PR00423 Cell division protein FtsZ signature 193 215 1.9E-49 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 PRINTS PR00423 Cell division protein FtsZ signature 130 151 1.9E-49 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 PRINTS PR00423 Cell division protein FtsZ signature 216 237 1.9E-49 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 PRINTS PR00423 Cell division protein FtsZ signature 102 122 1.9E-49 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Spica_1681 81166ba7405fdd4a7f0964aa41e5ed9f 397 SUPERFAMILY SSF52490 18 212 1.31E-68 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Spica_2525 e5267feaa9039927a66decaae98315c7 337 SUPERFAMILY SSF55874 232 284 4.07E-7 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2525 e5267feaa9039927a66decaae98315c7 337 Pfam PF13581 Histidine kinase-like ATPase domain 206 325 6.7E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2525 e5267feaa9039927a66decaae98315c7 337 Gene3D G3DSA:3.30.565.10 209 302 3.8E-6 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2382 6f3d6f20b4ec7bd702087a1d8d3bf8b9 337 Gene3D G3DSA:1.10.8.300 214 334 3.2E-36 T 13-10-2018 Spica_2382 6f3d6f20b4ec7bd702087a1d8d3bf8b9 337 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 7.2E-64 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Spica_2382 6f3d6f20b4ec7bd702087a1d8d3bf8b9 337 PIRSF PIRSF002849 1 337 2.3E-126 T 13-10-2018 Spica_2382 6f3d6f20b4ec7bd702087a1d8d3bf8b9 337 SUPERFAMILY SSF52540 12 309 2.91E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2382 6f3d6f20b4ec7bd702087a1d8d3bf8b9 337 Gene3D G3DSA:3.40.50.300 5 206 3.1E-46 T 13-10-2018 Spica_2736 dae8b6cb4330013668cc5f3ba269f745 459 SUPERFAMILY SSF81606 252 458 3.53E-9 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2736 dae8b6cb4330013668cc5f3ba269f745 459 SMART SM00331 238 457 3.5E-44 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2736 dae8b6cb4330013668cc5f3ba269f745 459 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 265 458 5.8E-32 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_2736 dae8b6cb4330013668cc5f3ba269f745 459 Gene3D G3DSA:3.60.40.10 212 457 2.9E-48 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0599 242df9fa1e5f7ab761e51b5579b96404 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 282 1.1E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0599 242df9fa1e5f7ab761e51b5579b96404 289 Gene3D G3DSA:1.10.3720.10 1 280 9.5E-67 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0599 242df9fa1e5f7ab761e51b5579b96404 289 SUPERFAMILY SSF161098 6 288 5.76E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 Pfam PF03783 Curli production assembly/transport component CsgG 463 567 1.5E-11 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 Gene3D G3DSA:3.40.50.10610 462 573 9.1E-8 T 13-10-2018 Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 Pfam PF00092 von Willebrand factor type A domain 191 358 1.3E-12 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 Gene3D G3DSA:3.40.50.410 186 364 2.3E-22 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 SMART SM00327 189 377 6.7E-14 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_2507 66331ba438969b1aafbaeb4d2bb148e9 579 SUPERFAMILY SSF53300 186 362 4.45E-25 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1422 1c0df48deedca5f41dd0657e7d8bbadb 204 Pfam PF14353 CpXC protein 5 118 3.0E-23 T 13-10-2018 IPR025682 CpXC domain Spica_2634 5ef08cf9a64905d9457ea1d1a42ab19e 306 Pfam PF00877 NlpC/P60 family 51 159 2.9E-24 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Spica_2634 5ef08cf9a64905d9457ea1d1a42ab19e 306 Gene3D G3DSA:3.90.1720.10 35 169 5.9E-38 T 13-10-2018 Spica_2634 5ef08cf9a64905d9457ea1d1a42ab19e 306 SUPERFAMILY SSF54001 30 161 2.94E-37 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_0829 0969d6afe63465b9e67dd405136b06d2 290 SUPERFAMILY SSF161098 14 289 1.44E-63 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0829 0969d6afe63465b9e67dd405136b06d2 290 Gene3D G3DSA:1.10.3720.10 8 277 3.0E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0829 0969d6afe63465b9e67dd405136b06d2 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 283 9.6E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 TIGRFAM TIGR00586 mutt: mutator mutT protein 4 124 2.8E-33 T 13-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 Pfam PF00293 NUDIX domain 4 122 5.1E-22 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 SUPERFAMILY SSF55811 2 124 2.44E-35 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 PRINTS PR00502 NUDIX hydrolase family signature 30 44 3.0E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 PRINTS PR00502 NUDIX hydrolase family signature 44 59 3.0E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0058 13c51b2410f806afbfe5763e9c931313 138 Gene3D G3DSA:3.90.79.10 1 132 2.2E-40 T 13-10-2018 Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 Gene3D G3DSA:3.40.50.1100 86 431 9.4E-123 T 13-10-2018 Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 96 388 2.2E-13 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 Gene3D G3DSA:3.40.50.1100 102 438 9.4E-123 T 13-10-2018 Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 96 110 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 SUPERFAMILY SSF53686 1 462 9.18E-124 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 Gene3D G3DSA:3.90.1380.10 1 84 2.6E-22 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily Spica_0244 a1ee3eec001a6cd37d7b92499592cf06 463 Pfam PF14821 Threonine synthase N terminus 2 80 2.7E-21 T 13-10-2018 IPR029144 Threonine synthase, N-terminal Spica_1254 01b64ed51f821114de653c5804dac94d 195 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 191 1.8E-53 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Spica_1254 01b64ed51f821114de653c5804dac94d 195 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 193 42.229 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 Spica_1254 01b64ed51f821114de653c5804dac94d 195 Gene3D G3DSA:3.90.950.10 1 194 4.7E-65 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Spica_1254 01b64ed51f821114de653c5804dac94d 195 SUPERFAMILY SSF52972 1 192 4.71E-58 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Spica_1254 01b64ed51f821114de653c5804dac94d 195 Pfam PF01725 Ham1 family 3 189 2.2E-53 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Spica_2761 4b00b94a452bc784a0947019ed0e67bb 221 Pfam PF03968 OstA-like protein 42 192 1.9E-4 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal Spica_0043 d7cc81a2f8e21735de8e9f277dd214a9 318 Pfam PF04468 PSP1 C-terminal conserved region 106 190 5.4E-29 T 13-10-2018 IPR007557 PSP1, C-terminal Spica_1006 4a5d09042c0c62dc7e7f7c2bf6f3c6ae 794 SMART SM00028 384 417 11.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1006 4a5d09042c0c62dc7e7f7c2bf6f3c6ae 794 SMART SM00028 503 536 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1006 4a5d09042c0c62dc7e7f7c2bf6f3c6ae 794 SUPERFAMILY SSF48452 388 538 1.79E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0471 00da48d5e298359e573495f69f621e28 121 SUPERFAMILY SSF52172 5 117 3.56E-22 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0471 00da48d5e298359e573495f69f621e28 121 SMART SM00448 6 111 6.4E-6 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0471 00da48d5e298359e573495f69f621e28 121 Pfam PF00072 Response regulator receiver domain 8 92 2.2E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0471 00da48d5e298359e573495f69f621e28 121 Gene3D G3DSA:3.40.50.2300 1 121 1.8E-19 T 13-10-2018 Spica_0067 d8988573199a86016fe047037ea7e85d 250 Gene3D G3DSA:1.10.10.10 1 62 2.2E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0067 d8988573199a86016fe047037ea7e85d 250 SMART SM00420 6 58 2.8E-17 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_0067 d8988573199a86016fe047037ea7e85d 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.1E-16 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_0067 d8988573199a86016fe047037ea7e85d 250 SUPERFAMILY SSF100950 75 232 2.2E-31 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_0067 d8988573199a86016fe047037ea7e85d 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Spica_0067 d8988573199a86016fe047037ea7e85d 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-6 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_0067 d8988573199a86016fe047037ea7e85d 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-6 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Spica_0067 d8988573199a86016fe047037ea7e85d 250 SMART SM01134 73 233 8.3E-64 T 13-10-2018 Spica_0067 d8988573199a86016fe047037ea7e85d 250 SUPERFAMILY SSF46785 4 65 3.82E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_0067 d8988573199a86016fe047037ea7e85d 250 Pfam PF00455 DeoR C terminal sensor domain 75 231 5.9E-49 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain Spica_1327 709114af31361a38a62cab22e6c3fccc 290 Gene3D G3DSA:3.40.50.720 2 277 2.8E-96 T 13-10-2018 Spica_1327 709114af31361a38a62cab22e6c3fccc 290 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 289 2.8E-90 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Spica_1327 709114af31361a38a62cab22e6c3fccc 290 SUPERFAMILY SSF51735 2 289 3.01E-89 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1327 709114af31361a38a62cab22e6c3fccc 290 Gene3D G3DSA:3.90.25.10 163 283 2.8E-96 T 13-10-2018 Spica_1327 709114af31361a38a62cab22e6c3fccc 290 Pfam PF04321 RmlD substrate binding domain 2 289 1.8E-97 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Spica_1278 468c069b8675845459735debae594ae1 351 Pfam PF03116 NQR2, RnfD, RnfE family 6 339 6.7E-54 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Spica_2111 afe7b9eac9af6186fbf58391dd3069ff 222 SUPERFAMILY SSF56784 6 220 9.07E-41 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2111 afe7b9eac9af6186fbf58391dd3069ff 222 Gene3D G3DSA:3.40.50.1000 69 222 2.2E-35 T 13-10-2018 IPR023214 HAD superfamily Spica_2111 afe7b9eac9af6186fbf58391dd3069ff 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 186 1.9E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Spica_2111 afe7b9eac9af6186fbf58391dd3069ff 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 192 1.1E-22 T 13-10-2018 Spica_0094 603fbff527f5f7ca45602172a53fba1c 211 Gene3D G3DSA:3.90.79.10 1 209 8.5E-49 T 13-10-2018 Spica_0094 603fbff527f5f7ca45602172a53fba1c 211 SUPERFAMILY SSF55811 52 206 8.12E-13 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0094 603fbff527f5f7ca45602172a53fba1c 211 Pfam PF00293 NUDIX domain 64 196 1.4E-6 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_2301 35f1f73b01f01a883f126477515e11de 162 SUPERFAMILY SSF55729 3 161 6.8E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2301 35f1f73b01f01a883f126477515e11de 162 Pfam PF13420 Acetyltransferase (GNAT) domain 4 154 6.9E-31 T 13-10-2018 Spica_2301 35f1f73b01f01a883f126477515e11de 162 Gene3D G3DSA:3.40.630.30 1 162 7.9E-51 T 13-10-2018 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 84 104 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 Gene3D G3DSA:3.40.1050.10 1 204 2.7E-66 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 Pfam PF00484 Carbonic anhydrase 34 192 9.5E-50 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 SMART SM00947 27 196 3.6E-61 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Spica_2258 5032a9c77f181a8e10b94eabefafabb7 206 SUPERFAMILY SSF53056 1 204 1.7E-60 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Spica_0637 3ed25791f45cafdf2223b0f85baff665 528 SUPERFAMILY SSF53850 32 510 1.34E-64 T 13-10-2018 Spica_0637 3ed25791f45cafdf2223b0f85baff665 528 Pfam PF13416 Bacterial extracellular solute-binding protein 69 373 4.3E-16 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0637 3ed25791f45cafdf2223b0f85baff665 528 Gene3D G3DSA:3.40.190.10 64 431 6.9E-62 T 13-10-2018 Spica_0637 3ed25791f45cafdf2223b0f85baff665 528 Gene3D G3DSA:3.40.190.10 160 512 6.9E-62 T 13-10-2018 Spica_1806 ca6928b0f30d48c416c13ccbf792e803 159 Gene3D G3DSA:2.30.30.40 11 140 3.4E-41 T 13-10-2018 Spica_1806 ca6928b0f30d48c416c13ccbf792e803 159 Gene3D G3DSA:2.40.50.180 28 141 3.4E-41 T 13-10-2018 Spica_1806 ca6928b0f30d48c416c13ccbf792e803 159 SMART SM00260 5 146 1.8E-40 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_1806 ca6928b0f30d48c416c13ccbf792e803 159 Pfam PF01584 CheW-like domain 9 147 8.5E-36 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Spica_1806 ca6928b0f30d48c416c13ccbf792e803 159 SUPERFAMILY SSF50341 8 149 4.32E-37 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 Gene3D G3DSA:3.30.420.40 154 317 1.2E-127 T 13-10-2018 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 SUPERFAMILY SSF53067 151 331 4.85E-49 T 13-10-2018 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 SUPERFAMILY SSF53067 11 146 4.06E-38 T 13-10-2018 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 Gene3D G3DSA:3.90.640.10 186 259 1.2E-127 T 13-10-2018 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 Gene3D G3DSA:3.30.420.40 14 327 1.2E-127 T 13-10-2018 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 49 67 1.4E-55 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 69 92 1.4E-55 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 187 207 1.4E-55 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 300 326 1.4E-55 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 132 151 1.4E-55 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 Pfam PF06723 MreB/Mbl protein 12 333 5.3E-147 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_1389 179570b9f71cc25ac75386daa2d7f7dc 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 11 334 3.4E-162 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 500 2.0E-120 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PIRSF PIRSF006615 2 506 1.4E-188 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 233 249 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 270 289 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 338 357 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 250 269 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 297 313 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 154 174 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 407 428 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 384 401 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 452 470 1.6E-68 T 13-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 SUPERFAMILY SSF55486 6 500 1.17E-112 T 13-10-2018 Spica_0439 2cb34e35e34a7188e132c54932599f8f 506 Gene3D G3DSA:1.10.1370.30 2 506 3.5E-205 T 13-10-2018 Spica_1603 91152931704e293168550fe7162f457e 67 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 31.27 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 9.8E-32 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 Pfam PF01197 Ribosomal protein L31 1 64 1.5E-32 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.3E-22 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 PRINTS PR01249 Ribosomal protein L31 signature 30 45 3.3E-22 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 PRINTS PR01249 Ribosomal protein L31 signature 45 63 3.3E-22 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_1603 91152931704e293168550fe7162f457e 67 Gene3D G3DSA:2.30.170.50 1 67 6.4E-33 T 13-10-2018 Spica_1603 91152931704e293168550fe7162f457e 67 SUPERFAMILY SSF143800 1 65 1.53E-26 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1782 ed704a3561f064bc7a399509b1aaa218 203 SUPERFAMILY SSF53254 1 173 9.03E-40 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Spica_1782 ed704a3561f064bc7a399509b1aaa218 203 PIRSF PIRSF000709 3 105 3.8E-6 T 13-10-2018 Spica_1782 ed704a3561f064bc7a399509b1aaa218 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 165 4.0E-34 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_1782 ed704a3561f064bc7a399509b1aaa218 203 SMART SM00855 3 156 1.1E-15 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_1782 ed704a3561f064bc7a399509b1aaa218 203 Gene3D G3DSA:3.40.50.1240 1 174 2.8E-39 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 PRINTS PR00625 DnaJ domain signature 98 116 5.7E-6 T 13-10-2018 IPR001623 DnaJ domain Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 PRINTS PR00625 DnaJ domain signature 116 131 5.7E-6 T 13-10-2018 IPR001623 DnaJ domain Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 PRINTS PR00625 DnaJ domain signature 137 157 5.7E-6 T 13-10-2018 IPR001623 DnaJ domain Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 Gene3D G3DSA:1.10.287.110 92 160 3.5E-11 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 SMART SM00271 95 157 9.9E-12 T 13-10-2018 IPR001623 DnaJ domain Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 Pfam PF00226 DnaJ domain 99 151 5.1E-9 T 13-10-2018 IPR001623 DnaJ domain Spica_1508 9c05fcefb4205182c91cea3c5d608d88 162 SUPERFAMILY SSF46565 69 153 3.27E-15 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 SMART SM00354 5 77 1.7E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 Gene3D G3DSA:3.40.50.2300 68 313 5.7E-72 T 13-10-2018 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 Gene3D G3DSA:3.40.50.2300 166 296 5.7E-72 T 13-10-2018 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 Pfam PF13377 Periplasmic binding protein-like domain 174 327 5.7E-38 T 13-10-2018 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 Gene3D G3DSA:1.10.260.40 1 64 2.6E-18 T 13-10-2018 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 6.7E-16 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 SUPERFAMILY SSF53822 79 350 2.54E-65 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0830 d97e4ebc0e71de98ccb705a4e3c3463f 357 SUPERFAMILY SSF47413 4 62 1.86E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 SUPERFAMILY SSF52518 4 210 9.1E-60 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 Gene3D G3DSA:3.40.50.920 241 354 5.4E-18 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 250 344 4.8E-20 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 SUPERFAMILY SSF52922 248 351 1.02E-18 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 204 6.7E-49 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 Spica_2637 cf17a1aa29c362db28bc10418c57fb10 354 Gene3D G3DSA:3.40.50.970 1 192 6.6E-62 T 13-10-2018 Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 SUPERFAMILY SSF51604 173 416 1.24E-80 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 Pfam PF05034 Methylaspartate ammonia-lyase N-terminus 1 168 3.2E-66 T 13-10-2018 IPR022665 Methylaspartate ammonia-lyase, N-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 Gene3D G3DSA:3.30.390.10 1 173 2.7E-58 T 13-10-2018 IPR029017 Enolase-like, N-terminal Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 TIGRFAM TIGR01502 B_methylAsp_ase: methylaspartate ammonia-lyase 2 417 1.1E-159 T 13-10-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 Gene3D G3DSA:3.20.20.120 174 422 2.1E-106 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 PIRSF PIRSF017107 1 422 1.0E-190 T 13-10-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 SUPERFAMILY SSF54826 1 169 3.38E-43 T 13-10-2018 Spica_1659 d546fa866c9cb0883306bc5c46a76087 425 Pfam PF07476 Methylaspartate ammonia-lyase C-terminus 171 416 1.6E-116 T 13-10-2018 IPR022662 Methylaspartate ammonia-lyase, C-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 219 351 1.7E-29 T 13-10-2018 IPR005249 Conserved hypothetical protein CHP00488 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 SUPERFAMILY SSF52374 1 188 5.32E-44 T 13-10-2018 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 189 27.603 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 188 6.6E-45 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 SMART SM00471 220 348 4.0E-5 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 5.8E-11 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 Pfam PF01467 Cytidylyltransferase-like 5 163 4.5E-25 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 Pfam PF01966 HD domain 224 337 3.4E-9 T 13-10-2018 IPR006674 HD domain Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 Gene3D G3DSA:3.40.50.620 1 198 5.4E-53 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 SUPERFAMILY SSF109604 208 390 1.48E-20 T 13-10-2018 Spica_0786 54c114c78e7b24eabab8a960b792dec3 395 Gene3D G3DSA:1.10.3210.10 208 392 3.4E-41 T 13-10-2018 Spica_1233 23ff7ea844115ebe630b6f99bc01815b 92 Gene3D G3DSA:3.30.70.240 1 87 9.7E-6 T 13-10-2018 Spica_1233 23ff7ea844115ebe630b6f99bc01815b 92 Pfam PF09827 CRISPR associated protein Cas2 5 66 4.3E-7 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Spica_1233 23ff7ea844115ebe630b6f99bc01815b 92 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 87 9.751 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Spica_1233 23ff7ea844115ebe630b6f99bc01815b 92 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 10 67 1.4E-6 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Spica_2481 5707e187edf0edd6f802a09e2209b5c5 194 Gene3D G3DSA:1.20.1270.390 23 122 1.9E-5 T 13-10-2018 Spica_2481 5707e187edf0edd6f802a09e2209b5c5 194 Pfam PF14346 Domain of unknown function (DUF4398) 16 97 9.6E-10 T 13-10-2018 IPR025511 Domain of unknown function DUF4398 Spica_1246 7de441126c5adfed4606309a06aaf240 161 Pfam PF00255 Glutathione peroxidase 5 112 2.2E-45 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Spica_1246 7de441126c5adfed4606309a06aaf240 161 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 Spica_1246 7de441126c5adfed4606309a06aaf240 161 PRINTS PR01011 Glutathione peroxidase family signature 123 132 2.0E-20 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Spica_1246 7de441126c5adfed4606309a06aaf240 161 PRINTS PR01011 Glutathione peroxidase family signature 23 40 2.0E-20 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Spica_1246 7de441126c5adfed4606309a06aaf240 161 PRINTS PR01011 Glutathione peroxidase family signature 58 74 2.0E-20 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Spica_1246 7de441126c5adfed4606309a06aaf240 161 SUPERFAMILY SSF52833 4 159 1.1E-61 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_1246 7de441126c5adfed4606309a06aaf240 161 Gene3D G3DSA:3.40.30.10 1 161 1.0E-72 T 13-10-2018 Spica_1246 7de441126c5adfed4606309a06aaf240 161 PIRSF PIRSF000303 1 161 8.4E-70 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Spica_0046 65baccfed19555fd4a1421a37b89db10 286 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 24 231 9.6E-62 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Spica_0046 65baccfed19555fd4a1421a37b89db10 286 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 20 239 30.112 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Spica_0046 65baccfed19555fd4a1421a37b89db10 286 SUPERFAMILY SSF69796 15 240 1.07E-66 T 13-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Spica_0046 65baccfed19555fd4a1421a37b89db10 286 Pfam PF02511 Thymidylate synthase complementing protein 26 225 7.4E-55 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 Spica_0046 65baccfed19555fd4a1421a37b89db10 286 Gene3D G3DSA:3.30.1360.170 7 245 9.0E-73 T 13-10-2018 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 Pfam PF13424 Tetratricopeptide repeat 272 338 5.0E-9 T 13-10-2018 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SMART SM00100 1 104 0.0041 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SUPERFAMILY SSF48452 237 347 6.42E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SMART SM00028 307 340 7.5E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SMART SM00028 270 303 0.063 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SMART SM00028 127 160 440.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SMART SM00028 234 266 240.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 Gene3D G3DSA:1.25.40.10 233 357 4.1E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 Pfam PF00027 Cyclic nucleotide-binding domain 6 91 1.9E-13 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 Gene3D G3DSA:2.60.120.10 2 122 4.1E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0772 0738ce67d9ccb9d9100f90a37b6828b4 357 SUPERFAMILY SSF51206 5 117 6.42E-20 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_2004 af26d48315993aef6d3fc82442091dfa 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 3.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 529 3.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 515 3.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 573 3.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 464 574 7.4E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2004 af26d48315993aef6d3fc82442091dfa 588 Gene3D G3DSA:3.30.565.10 425 577 5.7E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2004 af26d48315993aef6d3fc82442091dfa 588 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 417 1.1E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 SMART SM00388 352 419 2.0E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 SMART SM00387 463 576 1.1E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2004 af26d48315993aef6d3fc82442091dfa 588 SUPERFAMILY SSF47384 337 419 6.08E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 Gene3D G3DSA:1.10.287.130 343 421 1.7E-13 T 13-10-2018 Spica_2004 af26d48315993aef6d3fc82442091dfa 588 SUPERFAMILY SSF55874 410 574 1.18E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1673 ddc8c226991ce46d4cd8100a9db9d752 139 Pfam PF00460 Flagella basal body rod protein 16 41 4.6E-8 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Spica_1673 ddc8c226991ce46d4cd8100a9db9d752 139 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 7 139 1.2E-36 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Spica_1673 ddc8c226991ce46d4cd8100a9db9d752 139 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 17 37 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Spica_1673 ddc8c226991ce46d4cd8100a9db9d752 139 PIRSF PIRSF002889 2 139 4.0E-26 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Spica_0214 781c28f56d5cb1a3b985cda9e2fc4e73 408 Pfam PF07730 Histidine kinase 210 273 7.2E-10 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_0214 781c28f56d5cb1a3b985cda9e2fc4e73 408 Gene3D G3DSA:3.30.565.10 281 402 3.5E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0214 781c28f56d5cb1a3b985cda9e2fc4e73 408 SUPERFAMILY SSF55874 280 400 8.89E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 SUPERFAMILY SSF54197 3 177 1.42E-67 T 13-10-2018 IPR036265 HIT-like superfamily Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 3 350 7.7E-144 T 13-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 184 350 5.6E-57 T 13-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 SUPERFAMILY SSF54197 180 349 2.32E-53 T 13-10-2018 IPR036265 HIT-like superfamily Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 Gene3D G3DSA:3.30.428.10 41 175 4.3E-52 T 13-10-2018 IPR036265 HIT-like superfamily Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 Gene3D G3DSA:3.30.428.10 176 352 2.8E-72 T 13-10-2018 IPR036265 HIT-like superfamily Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 7 176 9.1E-68 T 13-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 PIRSF PIRSF000808 1 345 1.8E-121 T 13-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Spica_0454 590bbf9ed7566e1cd7b1923481e0f626 352 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 151 168 - T 13-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 Spica_0826 313af824e86c61908d6b86237f91fac8 374 SUPERFAMILY SSF54862 149 296 8.37E-21 T 13-10-2018 Spica_0826 313af824e86c61908d6b86237f91fac8 374 Pfam PF12838 4Fe-4S dicluster domain 199 243 9.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0826 313af824e86c61908d6b86237f91fac8 374 Pfam PF04015 Domain of unknown function (DUF362) 47 314 8.4E-43 T 13-10-2018 IPR007160 Domain of unknown function DUF362 Spica_0826 313af824e86c61908d6b86237f91fac8 374 Gene3D G3DSA:3.30.70.20 184 274 4.7E-12 T 13-10-2018 Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 Gene3D G3DSA:3.40.50.300 6 338 4.0E-93 T 13-10-2018 Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 313 9.2E-20 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 332 2.5E-26 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 Pfam PF00005 ABC transporter 41 194 6.5E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 SUPERFAMILY SSF52540 9 266 2.48E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2034 2a84dbfedcec0207563bc91ce6846118 338 SMART SM00382 49 252 1.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2489 4a5d1bb41f6658e73c0b5ec36b01ea16 221 Pfam PF01195 Peptidyl-tRNA hydrolase 4 198 7.3E-48 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spica_2489 4a5d1bb41f6658e73c0b5ec36b01ea16 221 SUPERFAMILY SSF53178 2 215 1.7E-48 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Spica_2489 4a5d1bb41f6658e73c0b5ec36b01ea16 221 Gene3D G3DSA:3.40.50.1470 1 206 5.7E-54 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Spica_2489 4a5d1bb41f6658e73c0b5ec36b01ea16 221 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 139 149 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Spica_2489 4a5d1bb41f6658e73c0b5ec36b01ea16 221 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 209 29.607 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 SUPERFAMILY SSF51366 16 264 1.13E-67 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 Pfam PF01680 SOR/SNZ family 5 210 2.2E-110 T 13-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 7 292 1.1E-149 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 ProSitePatterns PS01235 PdxS/SNZ family signature. 203 221 - T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 PIRSF PIRSF029271 1 292 2.5E-152 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 2 292 52.767 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 Spica_0931 088659f1f3beaa8389caf05705e3f3e2 292 Gene3D G3DSA:3.20.20.70 2 292 2.5E-150 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1021 4098d8381e7c36b92196f5fe0333ded7 318 Gene3D G3DSA:3.40.1190.20 5 318 3.4E-61 T 13-10-2018 IPR029056 Ribokinase-like Spica_1021 4098d8381e7c36b92196f5fe0333ded7 318 PIRSF PIRSF000535 4 317 8.3E-33 T 13-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 Spica_1021 4098d8381e7c36b92196f5fe0333ded7 318 SUPERFAMILY SSF53613 8 309 2.34E-38 T 13-10-2018 IPR029056 Ribokinase-like Spica_1021 4098d8381e7c36b92196f5fe0333ded7 318 Pfam PF00294 pfkB family carbohydrate kinase 26 308 8.0E-23 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 Pfam PF09827 CRISPR associated protein Cas2 1 78 3.3E-25 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 95 16.534 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 96 1.1E-22 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 PIRSF PIRSF032582 1 96 1.2E-40 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 SUPERFAMILY SSF143430 1 89 4.58E-27 T 13-10-2018 Spica_1923 a1637f5b57f1dd3d2f286ce7f0ad1da4 96 Gene3D G3DSA:3.30.70.240 1 96 1.9E-35 T 13-10-2018 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 Gene3D G3DSA:3.20.20.70 1 217 4.5E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 PIRSF PIRSF001461 1 217 1.1E-89 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 SUPERFAMILY SSF51366 4 216 5.1E-70 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 202 2.2E-76 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Spica_1367 4c26365c3a87b2581682d2cb93232941 217 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 215 1.0E-84 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Spica_0456 7db0fef1b95485dc104890be0c72b155 276 SUPERFAMILY SSF82689 174 272 1.96E-27 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Spica_0456 7db0fef1b95485dc104890be0c72b155 276 SUPERFAMILY SSF50182 108 173 1.08E-16 T 13-10-2018 IPR010920 LSM domain superfamily Spica_0456 7db0fef1b95485dc104890be0c72b155 276 SUPERFAMILY SSF82861 27 106 1.96E-10 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Spica_0456 7db0fef1b95485dc104890be0c72b155 276 Pfam PF00924 Mechanosensitive ion channel 64 262 6.3E-57 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Spica_0456 7db0fef1b95485dc104890be0c72b155 276 Gene3D G3DSA:2.30.30.60 124 171 1.8E-14 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Spica_0456 7db0fef1b95485dc104890be0c72b155 276 Gene3D G3DSA:3.30.70.100 174 267 1.7E-25 T 13-10-2018 Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 SUPERFAMILY SSF51735 156 339 4.77E-17 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 Gene3D G3DSA:3.90.180.10 14 353 2.8E-41 T 13-10-2018 Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 Pfam PF00107 Zinc-binding dehydrogenase 187 329 3.6E-11 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 117 1.0E-8 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 Gene3D G3DSA:3.40.50.720 156 320 2.8E-41 T 13-10-2018 Spica_2247 d71fc244a358c2df544fdeaacbd2f07e 420 SUPERFAMILY SSF50129 3 189 8.07E-22 T 13-10-2018 IPR011032 GroES-like superfamily Spica_2479 ff4a6ca73cd4a6280a2a37578a32c947 377 Gene3D G3DSA:3.90.1720.10 149 302 1.0E-7 T 13-10-2018 Spica_0026 4d024a5a530d8c18b83a8501f01eff08 294 Gene3D G3DSA:3.40.50.1820 30 291 1.5E-26 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_0026 4d024a5a530d8c18b83a8501f01eff08 294 Pfam PF12146 Serine aminopeptidase, S33 52 275 1.1E-24 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Spica_0026 4d024a5a530d8c18b83a8501f01eff08 294 SUPERFAMILY SSF53474 33 276 6.33E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 SUPERFAMILY SSF48029 243 452 6.02E-44 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Pfam PF14841 FliG middle domain 243 315 6.3E-20 T 13-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Pfam PF14842 FliG N-terminal domain 127 234 6.1E-27 T 13-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Gene3D G3DSA:1.10.220.30 125 231 4.4E-13 T 13-10-2018 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 241 264 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 399 425 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 322 347 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 353 373 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 155 181 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 375 395 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 PRINTS PR00954 Flagellar motor switch protein FliG signature 126 142 8.3E-35 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Pfam PF01706 FliG C-terminal domain 344 451 5.9E-25 T 13-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 SUPERFAMILY SSF48029 127 224 6.67E-13 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Gene3D G3DSA:1.10.220.30 232 320 2.6E-21 T 13-10-2018 Spica_1958 adb0fd9d1b6a8f1824e430c87ac8c9df 459 Gene3D G3DSA:1.10.220.30 322 459 4.6E-29 T 13-10-2018 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 Gene3D G3DSA:3.30.70.270 12 171 1.0E-23 T 13-10-2018 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 Gene3D G3DSA:2.30.40.20 29 81 1.0E-23 T 13-10-2018 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 SUPERFAMILY SSF56672 12 242 4.54E-44 T 13-10-2018 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 Gene3D G3DSA:3.30.1490.100 252 356 7.6E-6 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 Pfam PF00817 impB/mucB/samB family 18 161 9.2E-22 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Spica_1411 d05e5cd886d3b8431afa8b2450b1508e 414 Gene3D G3DSA:1.10.150.20 185 237 7.7E-10 T 13-10-2018 Spica_1461 65db2ead53b4e94b9557b2c486d27b4a 205 Pfam PF04991 LicD family 26 75 3.6E-13 T 13-10-2018 IPR007074 LicD family Spica_2571 8aa4c850b6708eb0620502047a6941b8 289 Gene3D G3DSA:3.90.930.1 16 160 1.6E-5 T 13-10-2018 Spica_0258 02769426d1f5edd6138b92f61c9c0fe5 253 Gene3D G3DSA:1.10.3210.10 54 251 5.3E-54 T 13-10-2018 Spica_0258 02769426d1f5edd6138b92f61c9c0fe5 253 SUPERFAMILY SSF109604 68 236 3.05E-32 T 13-10-2018 Spica_0258 02769426d1f5edd6138b92f61c9c0fe5 253 SMART SM00471 95 216 2.8E-6 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0258 02769426d1f5edd6138b92f61c9c0fe5 253 Pfam PF13023 HD domain 77 236 3.1E-33 T 13-10-2018 IPR006674 HD domain Spica_0092 83bc0b30b4861adfe9d8763732710594 134 Gene3D G3DSA:1.20.120.330 14 134 4.4E-24 T 13-10-2018 Spica_0092 83bc0b30b4861adfe9d8763732710594 134 SUPERFAMILY SSF81593 28 134 1.88E-21 T 13-10-2018 Spica_0092 83bc0b30b4861adfe9d8763732710594 134 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 14 134 2.4E-20 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 Spica_1360 71a82157bb94d000f7400ab6525c8bfd 425 Pfam PF03739 Predicted permease YjgP/YjgQ family 14 418 1.7E-75 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Spica_1409 19e6b7dcae68d0edcd2545705d8a4ce5 251 Gene3D G3DSA:1.25.10.110 95 166 2.2E-10 T 13-10-2018 Spica_1409 19e6b7dcae68d0edcd2545705d8a4ce5 251 SUPERFAMILY SSF48371 101 222 6.81E-11 T 13-10-2018 IPR016024 Armadillo-type fold Spica_1409 19e6b7dcae68d0edcd2545705d8a4ce5 251 Pfam PF13646 HEAT repeats 105 159 1.0E-9 T 13-10-2018 Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 Pfam PF01551 Peptidase family M23 230 324 1.6E-29 T 13-10-2018 IPR016047 Peptidase M23 Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 Gene3D G3DSA:2.70.70.10 188 330 1.9E-43 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 SMART SM00257 97 141 0.0072 T 13-10-2018 IPR018392 LysM domain Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 Pfam PF01476 LysM domain 98 141 3.0E-7 T 13-10-2018 IPR018392 LysM domain Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 SUPERFAMILY SSF51261 97 328 1.99E-50 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0857 3945bff7ed5752a67446fb4ad9629c0d 335 Gene3D G3DSA:3.10.350.10 92 145 1.7E-9 T 13-10-2018 IPR036779 LysM domain superfamily Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 Gene3D G3DSA:3.40.50.10810 89 350 2.7E-62 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 SUPERFAMILY SSF52540 313 554 9.03E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 SMART SM00487 88 293 7.0E-22 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 SUPERFAMILY SSF52540 68 279 1.48E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 Gene3D G3DSA:3.40.50.300 421 561 2.7E-5 T 13-10-2018 Spica_0499 ac683f2779a5856ac5c127ea506c6a8e 566 Pfam PF00176 SNF2 family N-terminal domain 113 344 3.6E-19 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Spica_1966 24a40c3169f7d0e6d0e6d62d0c8db066 447 SUPERFAMILY SSF53383 14 429 2.39E-54 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1966 24a40c3169f7d0e6d0e6d62d0c8db066 447 Gene3D G3DSA:3.40.640.10 57 279 1.4E-36 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1966 24a40c3169f7d0e6d0e6d62d0c8db066 447 Gene3D G3DSA:3.90.1150.10 280 445 1.4E-17 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1966 24a40c3169f7d0e6d0e6d62d0c8db066 447 Pfam PF00155 Aminotransferase class I and II 52 423 1.4E-28 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_0500 7847421a19c1cfa8ac2a2523b93fa58b 134 Pfam PF00953 Glycosyl transferase family 4 78 120 3.8E-6 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Spica_1497 3d1fe7d852c4b6bea96b5f1ff5354bef 377 SUPERFAMILY SSF48452 32 206 4.93E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2291 27a24e9613b0920369f5abc63e9e08a9 87 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 25 52 9.9E-6 T 13-10-2018 Spica_2291 27a24e9613b0920369f5abc63e9e08a9 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 21 62 3.0E-6 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_2291 27a24e9613b0920369f5abc63e9e08a9 87 SUPERFAMILY SSF143120 4 71 2.22E-8 T 13-10-2018 IPR036165 YefM-like superfamily Spica_2114 08a687ac0760f4ac913eee72e94a1b4e 205 Pfam PF01618 MotA/TolQ/ExbB proton channel family 69 188 1.5E-29 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Spica_2681 45b335f70db9c44f9643bdc3fa642243 291 Gene3D G3DSA:3.10.450.620 21 118 3.9E-6 T 13-10-2018 Spica_2681 45b335f70db9c44f9643bdc3fa642243 291 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 36 268 1.3E-28 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Spica_1242 e460942348e47c1c4f4da90de173f371 363 Gene3D G3DSA:3.30.590.10 12 256 7.8E-17 T 13-10-2018 Spica_1242 e460942348e47c1c4f4da90de173f371 363 SUPERFAMILY SSF55931 11 261 7.29E-19 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Spica_1242 e460942348e47c1c4f4da90de173f371 363 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 103 251 1.0E-5 T 13-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 364 5.6E-93 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 PIRSF PIRSF006487 1 372 2.9E-72 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 SUPERFAMILY SSF101790 287 370 4.58E-14 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Gene3D G3DSA:2.40.30.110 286 360 6.8E-17 T 13-10-2018 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 264 1.2E-80 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 SUPERFAMILY SSF103025 1 284 1.88E-85 T 13-10-2018 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Gene3D G3DSA:4.10.1250.10 243 282 3.7E-13 T 13-10-2018 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Gene3D G3DSA:3.30.1360.120 4 241 2.9E-76 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Gene3D G3DSA:3.30.70.1400 51 141 2.9E-76 T 13-10-2018 Spica_2357 cfff4ec5a3bbbb5251d24f880c87f669 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 360 7.3E-19 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 TIGRFAM TIGR01503 MthylAspMut_E: methylaspartate mutase, E subunit 3 481 3.6E-219 T 13-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 SUPERFAMILY SSF51703 3 481 3.88E-190 T 13-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 Gene3D G3DSA:3.20.20.240 1 416 6.8E-171 T 13-10-2018 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 Pfam PF06368 Methylaspartate mutase E chain (MutE) 40 481 1.8E-217 T 13-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 Hamap MF_01923 Glutamate mutase epsilon subunit [glmE]. 1 481 54.558 T 13-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 PIRSF PIRSF001495 1 482 2.9E-207 T 13-10-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_1658 034a6182bac57c47739bea944f31a4ff 482 Gene3D G3DSA:3.90.970.10 417 482 2.4E-24 T 13-10-2018 IPR014714 Glutamate mutase E subunit, C-terminal domain superfamily GO:0016866|GO:0019670|GO:0031419 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 Spica_2617 299e985dddf8ff965dd356e1034729f8 434 Gene3D G3DSA:3.90.1380.10 1 84 3.4E-11 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily Spica_2617 299e985dddf8ff965dd356e1034729f8 434 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 383 5.4E-20 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2617 299e985dddf8ff965dd356e1034729f8 434 TIGRFAM TIGR00260 thrC: threonine synthase 67 398 1.1E-68 T 13-10-2018 IPR004450 Threonine synthase-like Spica_2617 299e985dddf8ff965dd356e1034729f8 434 Gene3D G3DSA:3.40.50.1100 86 400 9.8E-112 T 13-10-2018 Spica_2617 299e985dddf8ff965dd356e1034729f8 434 Gene3D G3DSA:3.40.50.1100 103 406 9.8E-112 T 13-10-2018 Spica_2617 299e985dddf8ff965dd356e1034729f8 434 SUPERFAMILY SSF53686 1 432 4.66E-103 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2617 299e985dddf8ff965dd356e1034729f8 434 Pfam PF14821 Threonine synthase N terminus 3 67 7.0E-10 T 13-10-2018 IPR029144 Threonine synthase, N-terminal Spica_2017 dc9bc0ae4583f8610b05b1a75643073b 131 SUPERFAMILY SSF88723 4 129 1.01E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2017 dc9bc0ae4583f8610b05b1a75643073b 131 Gene3D G3DSA:3.40.50.1010 2 131 1.7E-11 T 13-10-2018 Spica_2017 dc9bc0ae4583f8610b05b1a75643073b 131 Pfam PF01850 PIN domain 6 123 8.6E-12 T 13-10-2018 IPR002716 PIN domain Spica_2754 7eb8e38369c27826f4ee4fbdea886e24 368 SUPERFAMILY SSF58104 153 337 8.37E-6 T 13-10-2018 Spica_2754 7eb8e38369c27826f4ee4fbdea886e24 368 Pfam PF02470 MlaD protein 41 102 1.1E-6 T 13-10-2018 IPR003399 Mce/MlaD Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.4E-10 T 13-10-2018 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.4E-10 T 13-10-2018 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 5.4E-10 T 13-10-2018 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 336 5.4E-10 T 13-10-2018 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 SUPERFAMILY SSF51905 5 379 1.44E-22 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 SUPERFAMILY SSF51905 5 211 2.12E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 265 4.7E-35 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.1E-6 T 13-10-2018 Spica_2583 a787bfe163fb9e08e1096d502874bc81 705 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 4.1E-6 T 13-10-2018 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 SUPERFAMILY SSF56601 6 290 6.4E-66 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 20 263 2.3E-55 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 SUPERFAMILY SSF69189 282 384 4.32E-9 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 150 1.4E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 110 127 1.4E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 53 64 1.4E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 Gene3D G3DSA:3.40.710.10 19 288 7.1E-78 T 13-10-2018 Spica_1629 9035e65e9454c48d7c1c68c9bc61287a 411 Gene3D G3DSA:2.60.410.10 291 386 2.9E-7 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Spica_1069 0dde03b37d24b58184ebb29fdada84cd 1010 Gene3D G3DSA:2.70.70.10 804 933 2.4E-7 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_2529 9b28efabe1c4f117479d32b7938547db 429 Pfam PF00860 Permease family 17 389 7.2E-47 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 Spica_2529 9b28efabe1c4f117479d32b7938547db 429 PIRSF PIRSF005353 1 429 1.9E-178 T 13-10-2018 IPR026033 Purine permease PbuG-like Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 SUPERFAMILY SSF46911 42 110 2.49E-27 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 Pfam PF01084 Ribosomal protein S18 56 106 6.5E-27 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 59 109 1.0E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 Gene3D G3DSA:4.10.640.10 29 111 8.6E-31 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 TIGRFAM TIGR00165 S18: ribosomal protein bS18 44 111 1.5E-33 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 PRINTS PR00974 Ribosomal protein S18 family signature 98 108 9.2E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 PRINTS PR00974 Ribosomal protein S18 family signature 66 76 9.2E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 PRINTS PR00974 Ribosomal protein S18 family signature 84 98 9.2E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 PRINTS PR00974 Ribosomal protein S18 family signature 76 83 9.2E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1427 2138d02ca66651fac6c9fd64cc968678 111 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 111 22.389 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_1804 19c773d4ac79696bd41a29a5d5143318 281 Pfam PF01513 ATP-NAD kinase 49 259 6.3E-52 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Spica_1804 19c773d4ac79696bd41a29a5d5143318 281 SUPERFAMILY SSF111331 4 276 1.57E-72 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Spica_1804 19c773d4ac79696bd41a29a5d5143318 281 Hamap MF_00361 NAD kinase [nadK]. 3 275 28.959 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Spica_1804 19c773d4ac79696bd41a29a5d5143318 281 Gene3D G3DSA:3.40.50.10330 48 276 1.3E-75 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Spica_1804 19c773d4ac79696bd41a29a5d5143318 281 Gene3D G3DSA:2.60.200.30 115 252 1.3E-75 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Spica_2838 d9bb879d58e727f34fe455f6e192fcd5 360 Gene3D G3DSA:3.40.50.2300 135 267 2.8E-29 T 13-10-2018 Spica_2838 d9bb879d58e727f34fe455f6e192fcd5 360 Gene3D G3DSA:3.40.50.2300 47 346 2.8E-29 T 13-10-2018 Spica_2838 d9bb879d58e727f34fe455f6e192fcd5 360 Pfam PF13458 Periplasmic binding protein 57 352 1.1E-12 T 13-10-2018 IPR028081 Leucine-binding protein domain Spica_2838 d9bb879d58e727f34fe455f6e192fcd5 360 SUPERFAMILY SSF53822 45 356 1.06E-26 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 SUPERFAMILY SSF56042 177 358 1.36E-44 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 SUPERFAMILY SSF55326 2 174 5.06E-41 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 359 2.5E-26 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Gene3D G3DSA:3.90.650.10 176 290 2.4E-36 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 1 284 2.0E-102 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Pfam PF00586 AIR synthase related protein, N-terminal domain 80 169 3.0E-14 T 13-10-2018 IPR016188 PurM-like, N-terminal domain Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 1 369 42.358 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Gene3D G3DSA:3.90.650.10 305 373 6.5E-10 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Spica_2415 aac7a96816dc8aac96569c0493b1fa03 399 Gene3D G3DSA:3.30.1330.10 1 175 1.0E-60 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Gene3D G3DSA:3.30.559.10 202 444 4.6E-82 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 SUPERFAMILY SSF52777 216 445 4.31E-73 T 13-10-2018 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Pfam PF00364 Biotin-requiring enzyme 9 76 4.6E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 215 445 7.7E-75 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 SUPERFAMILY SSF47005 145 187 7.46E-11 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Gene3D G3DSA:4.10.320.10 147 194 5.3E-16 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Pfam PF02817 e3 binding domain 149 182 2.8E-14 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 Gene3D G3DSA:2.40.50.100 2 100 1.9E-30 T 13-10-2018 Spica_1708 f37375576d7edae6573c20977e81b0a2 446 SUPERFAMILY SSF51230 2 94 8.51E-25 T 13-10-2018 IPR011053 Single hybrid motif Spica_0230 026d88bf819392602df57cfc1c027ab4 232 Pfam PF04012 PspA/IM30 family 2 222 3.3E-52 T 13-10-2018 IPR007157 PspA/IM30 Spica_1267 246e56f270570440ccfe0dd75d7338f7 539 Pfam PF05262 Borrelia P83/100 protein 29 508 3.6E-113 T 13-10-2018 IPR007926 Borrelia P83100 Spica_2464 6516897bb317d6755592c8c95b53efce 164 SMART SM01001 3 154 5.9E-105 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Spica_2464 6516897bb317d6755592c8c95b53efce 164 Pfam PF00731 AIR carboxylase 5 152 1.7E-65 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Spica_2464 6516897bb317d6755592c8c95b53efce 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 3.1E-67 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Spica_2464 6516897bb317d6755592c8c95b53efce 164 PIRSF PIRSF001338 1 163 5.8E-67 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 Spica_2464 6516897bb317d6755592c8c95b53efce 164 Gene3D G3DSA:3.40.50.7700 1 164 1.1E-74 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Spica_2464 6516897bb317d6755592c8c95b53efce 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.084 T 13-10-2018 IPR033747 Class I PurE Spica_2464 6516897bb317d6755592c8c95b53efce 164 SUPERFAMILY SSF52255 4 161 3.92E-67 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Spica_1483 cba8e51dd46860980766d757557a2c42 463 SUPERFAMILY SSF52425 19 197 8.63E-24 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 Spica_1483 cba8e51dd46860980766d757557a2c42 463 Pfam PF00875 DNA photolyase 21 149 7.0E-14 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 Spica_1483 cba8e51dd46860980766d757557a2c42 463 Gene3D G3DSA:3.40.50.620 1 140 1.7E-31 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1483 cba8e51dd46860980766d757557a2c42 463 SUPERFAMILY SSF48173 225 461 7.59E-51 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Spica_1483 cba8e51dd46860980766d757557a2c42 463 Gene3D G3DSA:1.25.40.80 141 321 7.4E-35 T 13-10-2018 Spica_1483 cba8e51dd46860980766d757557a2c42 463 Gene3D G3DSA:1.10.579.10 323 463 1.8E-60 T 13-10-2018 Spica_0564 16a2dbbf68b16aa548b01757d2a1ee5b 133 SUPERFAMILY SSF88723 1 129 2.61E-25 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0564 16a2dbbf68b16aa548b01757d2a1ee5b 133 Gene3D G3DSA:3.40.50.1010 1 131 1.7E-28 T 13-10-2018 Spica_0564 16a2dbbf68b16aa548b01757d2a1ee5b 133 Pfam PF01850 PIN domain 4 123 1.0E-14 T 13-10-2018 IPR002716 PIN domain Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 Gene3D G3DSA:2.60.40.10 408 503 4.6E-15 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 SMART SM00060 409 494 5.7E-5 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 143 287 1.9E-8 T 13-10-2018 Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 SUPERFAMILY SSF49265 402 492 2.76E-11 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 SUPERFAMILY SSF49899 135 289 8.82E-10 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 Pfam PF00041 Fibronectin type III domain 410 491 2.0E-5 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 Spica_2728 45a438f0b0e9fe3ceda67243d9db8105 512 Gene3D G3DSA:2.60.120.200 118 293 2.2E-9 T 13-10-2018 Spica_2564 b154efa36af43f6c20a9cac31254be1f 138 SUPERFAMILY SSF52172 4 130 4.27E-22 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2564 b154efa36af43f6c20a9cac31254be1f 138 Gene3D G3DSA:3.40.50.2300 2 133 4.7E-24 T 13-10-2018 Spica_2564 b154efa36af43f6c20a9cac31254be1f 138 SMART SM00448 4 124 4.3E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2564 b154efa36af43f6c20a9cac31254be1f 138 Pfam PF00072 Response regulator receiver domain 7 124 4.0E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2221 edab1dd7d8ac88da5aba5fa962da71d5 450 SUPERFAMILY SSF53850 33 449 1.05E-67 T 13-10-2018 Spica_2221 edab1dd7d8ac88da5aba5fa962da71d5 450 Gene3D G3DSA:3.40.190.10 35 450 1.2E-94 T 13-10-2018 Spica_2221 edab1dd7d8ac88da5aba5fa962da71d5 450 Pfam PF13416 Bacterial extracellular solute-binding protein 56 378 2.4E-30 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2685 cbe9321c5a0d28664b55d5254741af8e 82 Pfam PF13560 Helix-turn-helix domain 5 63 3.3E-10 T 13-10-2018 Spica_2685 cbe9321c5a0d28664b55d5254741af8e 82 Gene3D G3DSA:1.10.260.40 3 69 4.5E-12 T 13-10-2018 Spica_2685 cbe9321c5a0d28664b55d5254741af8e 82 SUPERFAMILY SSF47413 6 67 1.18E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_2685 cbe9321c5a0d28664b55d5254741af8e 82 SMART SM00530 9 65 2.2E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Spica_2781 612f522d949d4ef26e2e4f805c3419d4 241 Gene3D G3DSA:3.20.20.140 1 224 7.6E-30 T 13-10-2018 Spica_2781 612f522d949d4ef26e2e4f805c3419d4 241 Pfam PF02811 PHP domain 4 74 4.8E-11 T 13-10-2018 IPR004013 PHP domain GO:0003824 Spica_2781 612f522d949d4ef26e2e4f805c3419d4 241 SMART SM00481 3 71 9.3E-14 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_2781 612f522d949d4ef26e2e4f805c3419d4 241 SUPERFAMILY SSF89550 1 221 1.67E-30 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_2781 612f522d949d4ef26e2e4f805c3419d4 241 Pfam PF13263 PHP-associated 186 212 1.3E-5 T 13-10-2018 Spica_1732 b21e089e9a067d16e58cfb5ba420d246 139 Pfam PF12663 Protein of unknown function (DUF3788) 13 139 5.5E-34 T 13-10-2018 IPR024265 Protein of unknown function DUF3788 Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 TIGRFAM TIGR03542 DAPAT_plant: LL-diaminopimelate aminotransferase 4 404 2.1E-154 T 13-10-2018 IPR019942 LL-diaminopimelate aminotransferase/aminotransferase ALD1 GO:0008483 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 SUPERFAMILY SSF53383 16 402 2.47E-69 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 Hamap MF_01642 LL-diaminopimelate aminotransferase [dapL]. 3 405 45.93 T 13-10-2018 IPR019942 LL-diaminopimelate aminotransferase/aminotransferase ALD1 GO:0008483 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 Gene3D G3DSA:3.40.640.10 46 304 1.3E-124 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 Gene3D G3DSA:3.90.1150.10 19 402 1.3E-124 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0952 3ee6b52a2a5b84a638b66c9f278630da 407 Pfam PF00155 Aminotransferase class I and II 36 402 5.8E-36 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 Pfam PF13181 Tetratricopeptide repeat 154 184 0.026 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 SMART SM00028 231 264 0.039 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 SMART SM00028 151 184 5.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 SMART SM00028 191 224 0.05 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 Gene3D G3DSA:1.25.40.10 90 281 6.7E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 SUPERFAMILY SSF48452 130 273 2.34E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2753 ff7f9251ec8a1b0e65d77184525503a2 281 Pfam PF13424 Tetratricopeptide repeat 194 262 4.3E-10 T 13-10-2018 Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 Gene3D G3DSA:3.30.70.270 156 324 8.2E-24 T 13-10-2018 Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 Gene3D G3DSA:2.60.120.10 4 154 6.9E-24 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 Pfam PF00990 Diguanylate cyclase, GGDEF domain 163 318 2.5E-18 T 13-10-2018 IPR000160 GGDEF domain Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 SUPERFAMILY SSF51206 8 111 3.54E-21 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 SUPERFAMILY SSF55073 169 323 1.73E-18 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 159 269 1.7E-14 T 13-10-2018 IPR000160 GGDEF domain Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 SMART SM00267 152 323 1.8E-10 T 13-10-2018 IPR000160 GGDEF domain Spica_2522 bd95c4f118351cb157f1e792968fe06b 335 Pfam PF00027 Cyclic nucleotide-binding domain 35 111 5.1E-14 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_1608 8d93e80ba32b6833905767d0d07b9be7 241 SMART SM00448 5 121 5.4E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1608 8d93e80ba32b6833905767d0d07b9be7 241 Gene3D G3DSA:3.40.50.12740 4 241 2.6E-49 T 13-10-2018 Spica_1608 8d93e80ba32b6833905767d0d07b9be7 241 Pfam PF00072 Response regulator receiver domain 7 121 3.2E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_1608 8d93e80ba32b6833905767d0d07b9be7 241 SUPERFAMILY SSF52172 4 141 4.27E-42 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 Gene3D G3DSA:3.40.50.720 1 205 4.2E-56 T 13-10-2018 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 SUPERFAMILY SSF51735 1 198 1.35E-22 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 107 8.2E-17 T 13-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 PRINTS PR00084 Mannitol dehydrogenase signature 117 130 7.2E-5 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 7.2E-5 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 PRINTS PR00084 Mannitol dehydrogenase signature 151 164 7.2E-5 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 PRINTS PR00084 Mannitol dehydrogenase signature 173 188 7.2E-5 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 SUPERFAMILY SSF48179 221 373 8.5E-20 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 170 391 8.0E-21 T 13-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 Spica_0129 f10f35d21bd75f52f57e0998e0834ae3 405 Gene3D G3DSA:1.10.1040.10 224 405 5.8E-47 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Spica_1783 9c701e51c2e89f4bfba88f2acd9cff46 335 Gene3D G3DSA:2.30.30.40 246 318 1.4E-11 T 13-10-2018 Spica_2448 438ce79190523415c20299103f9c5a45 192 SUPERFAMILY SSF48452 2 187 4.28E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2448 438ce79190523415c20299103f9c5a45 192 Pfam PF10300 Protein of unknown function (DUF3808) 42 176 1.6E-5 T 13-10-2018 IPR019412 Inclusion body clearance protein Iml2/Tetratricopeptide repeat protein 39 Spica_2448 438ce79190523415c20299103f9c5a45 192 Gene3D G3DSA:1.25.40.10 1 192 3.7E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0415 2a55e21d11619c154cc719e3e1186214 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 122 398 2.2E-48 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1093 e97e557060e9e93c66cb9fe5d310fd66 112 Gene3D G3DSA:3.30.750.24 1 111 8.9E-26 T 13-10-2018 IPR036513 STAS domain superfamily Spica_1093 e97e557060e9e93c66cb9fe5d310fd66 112 SUPERFAMILY SSF52091 1 108 7.26E-27 T 13-10-2018 IPR036513 STAS domain superfamily Spica_1093 e97e557060e9e93c66cb9fe5d310fd66 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 4.3E-28 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spica_1093 e97e557060e9e93c66cb9fe5d310fd66 112 Pfam PF01740 STAS domain 4 106 3.9E-18 T 13-10-2018 IPR002645 STAS domain Spica_0025 8d67d9daaae23e19abd7e502c81d47db 272 Pfam PF08902 Domain of unknown function (DUF1848) 2 271 2.1E-80 T 13-10-2018 IPR014998 Protein of unknown function DUF1848 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 SMART SM00028 98 131 21.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 SMART SM00028 30 63 0.012 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 SMART SM00028 198 231 330.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 SMART SM00028 64 97 25.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 SUPERFAMILY SSF48452 31 228 2.92E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 Gene3D G3DSA:1.25.40.10 25 131 3.4E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 Gene3D G3DSA:1.25.40.10 132 236 3.2E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 113 188 4.6E-7 T 13-10-2018 Spica_1494 4107a8557d7b6c9cab2580ac1bcff757 307 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 29 88 5.3E-7 T 13-10-2018 Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 SUPERFAMILY SSF55785 454 590 1.58E-6 T 13-10-2018 IPR035965 PAS domain superfamily Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 Gene3D G3DSA:3.30.565.10 602 761 5.0E-10 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 Gene3D G3DSA:3.30.450.20 458 590 1.1E-7 T 13-10-2018 Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 Pfam PF13581 Histidine kinase-like ATPase domain 630 756 1.5E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 Pfam PF07695 7TM diverse intracellular signalling 214 350 8.7E-11 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 Spica_2526 b42536e47bb2bad8522c0c0948d859ba 762 SUPERFAMILY SSF55874 615 738 1.57E-5 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.10 1286 1389 1.2E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.10 1806 1907 4.1E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.10 872 981 1.7E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.10 37 141 8.2E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 SUPERFAMILY SSF81296 787 858 9.8E-7 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.650 773 870 3.7E-8 T 13-10-2018 Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 Gene3D G3DSA:2.60.40.650 1714 1791 8.4E-6 T 13-10-2018 Spica_1998 9f16310e71dbc0bd7f22074aab6a55c6 3372 SUPERFAMILY SSF81296 1727 1788 3.78E-7 T 13-10-2018 IPR014756 Immunoglobulin E-set Spica_0648 4f8be338462a613e7c6ed42c3aca647c 205 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 197 24.761 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Spica_0648 4f8be338462a613e7c6ed42c3aca647c 205 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 6 194 6.6E-67 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 Spica_0648 4f8be338462a613e7c6ed42c3aca647c 205 PIRSF PIRSF006102 1 205 1.9E-71 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_0648 4f8be338462a613e7c6ed42c3aca647c 205 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 186 6.7E-61 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 608 782 6.0E-35 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 Pfam PF05226 CHASE2 domain 26 510 9.9E-37 T 13-10-2018 IPR007890 CHASE2 Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 SMART SM00044 570 768 5.7E-19 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 SUPERFAMILY SSF55073 602 787 9.26E-61 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 SMART SM01080 36 514 9.3E-31 T 13-10-2018 IPR007890 CHASE2 Spica_1382 9ecc95fae01d0ec439141799aab0c6ba 808 Gene3D G3DSA:3.30.70.1230 601 793 1.1E-71 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0320 d8d13528706da9e997cdeb34e3682f40 142 SUPERFAMILY SSF82649 5 140 2.04E-36 T 13-10-2018 Spica_0320 d8d13528706da9e997cdeb34e3682f40 142 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 136 9.7E-40 T 13-10-2018 Spica_0320 d8d13528706da9e997cdeb34e3682f40 142 Gene3D G3DSA:3.90.1010.10 1 141 5.9E-41 T 13-10-2018 Spica_0320 d8d13528706da9e997cdeb34e3682f40 142 Pfam PF01592 NifU-like N terminal domain 9 124 5.4E-18 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Spica_1935 c3612bf4d55ce3cd760c53447bad5b49 317 SUPERFAMILY SSF103481 44 149 5.1E-12 T 13-10-2018 Spica_1935 c3612bf4d55ce3cd760c53447bad5b49 317 SUPERFAMILY SSF103481 217 315 3.92E-12 T 13-10-2018 Spica_1935 c3612bf4d55ce3cd760c53447bad5b49 317 Pfam PF00892 EamA-like transporter family 177 315 8.5E-19 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_1935 c3612bf4d55ce3cd760c53447bad5b49 317 Pfam PF00892 EamA-like transporter family 9 145 3.2E-16 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 ProSitePatterns PS00151 Acylphosphatase signature 2. 40 56 - T 13-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 PRINTS PR00112 Acylphosphatase signature 11 26 6.6E-9 T 13-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 PRINTS PR00112 Acylphosphatase signature 32 57 6.6E-9 T 13-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 Gene3D G3DSA:3.30.70.100 4 97 3.4E-30 T 13-10-2018 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 ProSitePatterns PS00150 Acylphosphatase signature 1. 16 26 - T 13-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 SUPERFAMILY SSF54975 10 97 2.09E-29 T 13-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0472 2d6a0ebd5dccdb2f3bc676df1ac90500 98 Pfam PF00708 Acylphosphatase 14 96 1.4E-26 T 13-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 47 2.9E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 Pfam PF13407 Periplasmic binding protein domain 69 316 8.4E-22 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 Gene3D G3DSA:3.40.50.2300 69 329 3.7E-58 T 13-10-2018 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 SUPERFAMILY SSF47413 1 57 8.28E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 SMART SM00354 1 71 4.5E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 SUPERFAMILY SSF53822 69 332 2.23E-29 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 Gene3D G3DSA:1.10.260.40 1 57 6.2E-20 T 13-10-2018 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 Gene3D G3DSA:3.40.50.2300 166 338 3.7E-58 T 13-10-2018 Spica_0055 f921f8efafed7288a459501e2cfc13ef 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 13-10-2018 Spica_1302 e26837ff8f8c0e5a86135c26eda6fe1a 428 Gene3D G3DSA:3.80.30.20 1 316 1.7E-75 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1302 e26837ff8f8c0e5a86135c26eda6fe1a 428 SUPERFAMILY SSF102114 4 419 2.94E-79 T 13-10-2018 Spica_1302 e26837ff8f8c0e5a86135c26eda6fe1a 428 Pfam PF04055 Radical SAM superfamily 7 183 5.5E-9 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1302 e26837ff8f8c0e5a86135c26eda6fe1a 428 SMART SM00729 2 235 1.6E-34 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1302 e26837ff8f8c0e5a86135c26eda6fe1a 428 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 288 2.1E-61 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 Spica_2222 fdc3fbb71c47747adc6c14ab45e23e64 300 SUPERFAMILY SSF161098 12 297 1.96E-61 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2222 fdc3fbb71c47747adc6c14ab45e23e64 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 285 1.0E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2222 fdc3fbb71c47747adc6c14ab45e23e64 300 Gene3D G3DSA:1.10.3720.10 5 288 2.9E-60 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0560 877f201b37beb3c6cd4287c10dd255f8 206 Pfam PF00702 haloacid dehalogenase-like hydrolase 60 164 3.7E-9 T 13-10-2018 Spica_0560 877f201b37beb3c6cd4287c10dd255f8 206 Gene3D G3DSA:3.40.50.1000 3 191 9.3E-74 T 13-10-2018 IPR023214 HAD superfamily Spica_0560 877f201b37beb3c6cd4287c10dd255f8 206 SUPERFAMILY SSF56784 1 182 1.05E-37 T 13-10-2018 IPR036412 HAD-like superfamily Spica_0560 877f201b37beb3c6cd4287c10dd255f8 206 TIGRFAM TIGR02137 HSK-PSP: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein 2 198 1.1E-76 T 13-10-2018 IPR011863 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 Spica_0560 877f201b37beb3c6cd4287c10dd255f8 206 Gene3D G3DSA:3.90.1470.10 13 128 9.3E-74 T 13-10-2018 Spica_1460 862506a84d536c7f2f7811f5de14b260 387 Pfam PF13692 Glycosyl transferases group 1 215 351 8.6E-22 T 13-10-2018 Spica_1460 862506a84d536c7f2f7811f5de14b260 387 Gene3D G3DSA:3.40.50.2000 22 194 1.0E-34 T 13-10-2018 Spica_1460 862506a84d536c7f2f7811f5de14b260 387 SUPERFAMILY SSF53756 15 384 1.02E-44 T 13-10-2018 Spica_1460 862506a84d536c7f2f7811f5de14b260 387 Gene3D G3DSA:3.40.50.2000 195 365 1.0E-34 T 13-10-2018 Spica_0764 21ee19477098e91a684fea60d0cf7837 528 Pfam PF01704 UTP--glucose-1-phosphate uridylyltransferase 283 467 1.1E-12 T 13-10-2018 IPR002618 UDPGP family GO:0070569 Spica_0764 21ee19477098e91a684fea60d0cf7837 528 SUPERFAMILY SSF53448 203 461 1.61E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0764 21ee19477098e91a684fea60d0cf7837 528 Gene3D G3DSA:3.90.550.10 174 459 5.8E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2141 a057abd19e846e143c0837578a9087a7 316 SUPERFAMILY SSF161098 8 275 4.06E-49 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2141 a057abd19e846e143c0837578a9087a7 316 Gene3D G3DSA:1.10.3720.10 18 285 7.1E-47 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2141 a057abd19e846e143c0837578a9087a7 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 278 5.8E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2388 617b5884fe51ac13294a0afba1d217f0 144 SMART SM00100 12 125 1.1E-9 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_2388 617b5884fe51ac13294a0afba1d217f0 144 Gene3D G3DSA:2.60.120.10 2 143 4.2E-25 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_2388 617b5884fe51ac13294a0afba1d217f0 144 SUPERFAMILY SSF51206 7 138 1.01E-23 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Spica_2388 617b5884fe51ac13294a0afba1d217f0 144 Pfam PF00027 Cyclic nucleotide-binding domain 31 111 3.9E-13 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Spica_0369 2eee63ebe1868b2f0951884407abbbb1 390 SUPERFAMILY SSF52540 15 139 3.1E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0369 2eee63ebe1868b2f0951884407abbbb1 390 Pfam PF13173 AAA domain 22 137 1.7E-24 T 13-10-2018 Spica_0369 2eee63ebe1868b2f0951884407abbbb1 390 SUPERFAMILY SSF52980 228 376 4.83E-6 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_0369 2eee63ebe1868b2f0951884407abbbb1 390 Pfam PF13635 Domain of unknown function (DUF4143) 179 338 2.0E-29 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_1268 50e592b0db10acac1c65029180e4beef 582 SUPERFAMILY SSF50998 35 286 9.68E-16 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spica_1268 50e592b0db10acac1c65029180e4beef 582 SUPERFAMILY SSF48371 459 575 5.83E-9 T 13-10-2018 IPR016024 Armadillo-type fold Spica_1268 50e592b0db10acac1c65029180e4beef 582 Gene3D G3DSA:1.25.10.10 456 582 4.7E-10 T 13-10-2018 IPR011989 Armadillo-like helical Spica_1268 50e592b0db10acac1c65029180e4beef 582 SUPERFAMILY SSF50998 256 379 1.8E-6 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Spica_1268 50e592b0db10acac1c65029180e4beef 582 Pfam PF13360 PQQ-like domain 36 123 2.9E-7 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Spica_1268 50e592b0db10acac1c65029180e4beef 582 Gene3D G3DSA:2.130.10.10 28 324 5.4E-20 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_1268 50e592b0db10acac1c65029180e4beef 582 SMART SM00564 129 159 500.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_1268 50e592b0db10acac1c65029180e4beef 582 SMART SM00564 50 80 250.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_1268 50e592b0db10acac1c65029180e4beef 582 SMART SM00564 89 120 0.25 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Spica_2847 cc9af5e38b68223763fd5305f7496a1c 292 SUPERFAMILY SSF161098 55 281 5.23E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2847 cc9af5e38b68223763fd5305f7496a1c 292 SUPERFAMILY SSF160964 7 45 1.83E-5 T 13-10-2018 Spica_2847 cc9af5e38b68223763fd5305f7496a1c 292 Gene3D G3DSA:1.10.3720.10 51 292 4.7E-68 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2847 cc9af5e38b68223763fd5305f7496a1c 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 287 9.8E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2684 8ff43540f43b337af7f6550ea8ac0e9c 394 Pfam PF07804 HipA-like C-terminal domain 146 361 7.3E-42 T 13-10-2018 IPR012893 HipA-like, C-terminal Spica_2684 8ff43540f43b337af7f6550ea8ac0e9c 394 Gene3D G3DSA:1.10.1070.20 226 312 2.4E-5 T 13-10-2018 Spica_2684 8ff43540f43b337af7f6550ea8ac0e9c 394 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 3 96 9.0E-9 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Spica_2684 8ff43540f43b337af7f6550ea8ac0e9c 394 Pfam PF13657 HipA N-terminal domain 3 99 2.8E-14 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Spica_2716 31effa308ba549a48b9f6292f6381783 352 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 17 329 5.6E-32 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Spica_2716 31effa308ba549a48b9f6292f6381783 352 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 17 342 1.2E-25 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 SMART SM00028 63 96 360.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 SMART SM00028 109 142 4.0E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 SMART SM00028 27 60 91.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 Gene3D G3DSA:1.25.40.10 26 94 4.5E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 Pfam PF13432 Tetratricopeptide repeat 33 90 0.0022 T 13-10-2018 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 Pfam PF00515 Tetratricopeptide repeat 110 139 7.0E-7 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 SUPERFAMILY SSF48452 29 155 6.58E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2377 9b9400e8aa6cf88fbae739a4f16a437f 208 Gene3D G3DSA:1.25.40.10 107 205 7.7E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1204 c77dbd2978475eebda1517d14db9fedc 284 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 11 274 1.9E-42 T 13-10-2018 IPR018708 Protein of unknown function DUF2225 Spica_0626 5ebd871ffb8965a6968b02e248ebcb57 345 Pfam PF00294 pfkB family carbohydrate kinase 3 316 7.6E-35 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_0626 5ebd871ffb8965a6968b02e248ebcb57 345 SUPERFAMILY SSF53613 3 335 1.64E-75 T 13-10-2018 IPR029056 Ribokinase-like Spica_0626 5ebd871ffb8965a6968b02e248ebcb57 345 Gene3D G3DSA:3.40.1190.20 1 345 5.5E-129 T 13-10-2018 IPR029056 Ribokinase-like Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 Pfam PF03727 Hexokinase 225 450 4.5E-39 T 13-10-2018 IPR022673 Hexokinase, C-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 Pfam PF00349 Hexokinase 29 199 1.2E-28 T 13-10-2018 IPR022672 Hexokinase, N-terminal GO:0005524|GO:0005975|GO:0016773 KEGG: 00010+2.7.1.1|KEGG: 00051+2.7.1.1|KEGG: 00052+2.7.1.1|KEGG: 00500+2.7.1.1|KEGG: 00520+2.7.1.1|KEGG: 00521+2.7.1.1|KEGG: 00524+2.7.1.1|Reactome: R-HSA-70171 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 SUPERFAMILY SSF53067 224 450 2.81E-33 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 Gene3D G3DSA:3.30.420.40 55 448 1.5E-87 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 Gene3D G3DSA:3.40.367.20 36 442 1.5E-87 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 285 307 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 361 383 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 133 158 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 225 239 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 68 84 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 PRINTS PR00475 Hexokinase family signature 435 451 1.3E-25 T 13-10-2018 Spica_0992 51aa9ef68371d62a8e942b8c463b3546 452 SUPERFAMILY SSF53067 19 200 3.89E-36 T 13-10-2018 Spica_0404 dd030536aa6c69b3128ea3540e7018d0 150 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 145 9.9E-38 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P Spica_0404 dd030536aa6c69b3128ea3540e7018d0 150 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 144 1.4E-51 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0404 dd030536aa6c69b3128ea3540e7018d0 150 SUPERFAMILY SSF52080 5 146 6.15E-42 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Spica_0404 dd030536aa6c69b3128ea3540e7018d0 150 Gene3D G3DSA:3.100.10.10 70 147 1.6E-21 T 13-10-2018 Spica_0404 dd030536aa6c69b3128ea3540e7018d0 150 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 4 147 20.122 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Spica_1775 13e923b5c76debabd8ca614d7cc696d6 160 Gene3D G3DSA:3.40.630.30 16 148 8.8E-21 T 13-10-2018 Spica_1775 13e923b5c76debabd8ca614d7cc696d6 160 Pfam PF13673 Acetyltransferase (GNAT) domain 44 155 2.8E-10 T 13-10-2018 IPR000182 GNAT domain Spica_1775 13e923b5c76debabd8ca614d7cc696d6 160 SUPERFAMILY SSF55729 40 138 3.06E-15 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_0725 80e8f5fada6865cd127374ec80953a99 432 SUPERFAMILY SSF53850 28 427 5.43E-59 T 13-10-2018 Spica_0725 80e8f5fada6865cd127374ec80953a99 432 Gene3D G3DSA:3.40.190.10 52 356 3.0E-61 T 13-10-2018 Spica_0725 80e8f5fada6865cd127374ec80953a99 432 Gene3D G3DSA:3.40.190.10 143 416 3.0E-61 T 13-10-2018 Spica_0725 80e8f5fada6865cd127374ec80953a99 432 Pfam PF13416 Bacterial extracellular solute-binding protein 49 333 4.1E-33 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2001 3d943f79e4e9e71706da7c21efaae283 459 Pfam PF02687 FtsX-like permease family 359 445 8.1E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_2001 3d943f79e4e9e71706da7c21efaae283 459 Pfam PF12704 MacB-like periplasmic core domain 18 297 3.1E-15 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Spica_0257 9361145fa7706a58cdce730ed86b78c5 415 Gene3D G3DSA:1.20.1250.20 25 406 1.3E-38 T 13-10-2018 Spica_0257 9361145fa7706a58cdce730ed86b78c5 415 SUPERFAMILY SSF103473 26 409 9.81E-48 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_0257 9361145fa7706a58cdce730ed86b78c5 415 Pfam PF07690 Major Facilitator Superfamily 30 325 8.6E-27 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_0985 165aabf916e1d9cbcac370cde8d9db79 125 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 93 6.7E-28 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Spica_0985 165aabf916e1d9cbcac370cde8d9db79 125 PIRSF PIRSF006113 1 125 3.4E-25 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Spica_0985 165aabf916e1d9cbcac370cde8d9db79 125 Gene3D G3DSA:3.30.479.10 1 124 3.0E-34 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Spica_0985 165aabf916e1d9cbcac370cde8d9db79 125 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 123 1.6E-34 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Spica_0985 165aabf916e1d9cbcac370cde8d9db79 125 SUPERFAMILY SSF55620 1 124 2.33E-38 T 13-10-2018 Spica_0004 473bfb2ea5ee8e50a3ba686a686922c0 158 Pfam PF05258 Protein of unknown function (DUF721) 4 90 8.2E-15 T 13-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 Gene3D G3DSA:3.50.50.60 8 296 2.2E-108 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 2.3E-60 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 303 6.8E-114 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 292 5.5E-47 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 SUPERFAMILY SSF51905 1 303 3.89E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 4.2E-33 T 13-10-2018 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 4.2E-33 T 13-10-2018 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.2E-33 T 13-10-2018 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 4.2E-33 T 13-10-2018 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 4.2E-33 T 13-10-2018 Spica_0845 bc8121ea8fb82bc04f0ca373aef2cfe8 312 Gene3D G3DSA:3.50.50.60 117 239 2.2E-108 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2862 b4eebcfc6ec73d43c81d85158f007d97 205 Gene3D G3DSA:3.90.1720.10 58 204 1.3E-20 T 13-10-2018 Spica_2862 b4eebcfc6ec73d43c81d85158f007d97 205 SUPERFAMILY SSF54001 60 185 2.78E-17 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_2862 b4eebcfc6ec73d43c81d85158f007d97 205 Pfam PF00877 NlpC/P60 family 78 183 1.7E-11 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Spica_0190 344fbba68987ee90f5e41ddfaa7cebf4 461 SUPERFAMILY SSF56954 4 454 1.28E-61 T 13-10-2018 Spica_0190 344fbba68987ee90f5e41ddfaa7cebf4 461 Pfam PF02321 Outer membrane efflux protein 30 234 9.8E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_0190 344fbba68987ee90f5e41ddfaa7cebf4 461 Pfam PF02321 Outer membrane efflux protein 257 452 6.8E-18 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_0190 344fbba68987ee90f5e41ddfaa7cebf4 461 Gene3D G3DSA:1.20.1600.10 25 453 3.9E-63 T 13-10-2018 Spica_0577 19784da55aafdde72298bf74d46813c3 151 Gene3D G3DSA:2.60.40.790 6 150 4.7E-37 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_0577 19784da55aafdde72298bf74d46813c3 151 SUPERFAMILY SSF49764 17 150 8.2E-40 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_0577 19784da55aafdde72298bf74d46813c3 151 Pfam PF00011 Hsp20/alpha crystallin family 49 149 3.6E-26 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Spica_1796 adfe43f91ec79f38568a10d3aaf39835 291 SUPERFAMILY SSF50156 187 271 8.54E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Spica_1796 adfe43f91ec79f38568a10d3aaf39835 291 Pfam PF13180 PDZ domain 210 271 1.1E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_1796 adfe43f91ec79f38568a10d3aaf39835 291 Gene3D G3DSA:2.30.42.10 183 279 6.2E-14 T 13-10-2018 Spica_1796 adfe43f91ec79f38568a10d3aaf39835 291 SMART SM00228 187 269 4.6E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Spica_2298 3b385e94e9e45b6dbdaabc582e936286 520 Gene3D G3DSA:3.40.50.1820 2 493 2.4E-117 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2298 3b385e94e9e45b6dbdaabc582e936286 520 SUPERFAMILY SSF53474 4 480 3.21E-100 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2298 3b385e94e9e45b6dbdaabc582e936286 520 Pfam PF00135 Carboxylesterase family 5 334 1.4E-77 T 13-10-2018 IPR002018 Carboxylesterase, type B Spica_2298 3b385e94e9e45b6dbdaabc582e936286 520 Pfam PF00135 Carboxylesterase family 380 472 1.1E-9 T 13-10-2018 IPR002018 Carboxylesterase, type B Spica_2298 3b385e94e9e45b6dbdaabc582e936286 520 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 187 202 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Spica_0913 d75fe37d714a95b80dd82353aa8063e6 323 SUPERFAMILY SSF69917 35 254 8.63E-20 T 13-10-2018 IPR020080 Outer membrane adhesin/peptidase omptin GO:0004190 Spica_0913 d75fe37d714a95b80dd82353aa8063e6 323 Pfam PF01278 Omptin family 38 258 8.2E-18 T 13-10-2018 IPR000036 Peptidase A26, omptin GO:0004175|GO:0006508|GO:0009279 Spica_0913 d75fe37d714a95b80dd82353aa8063e6 323 Gene3D G3DSA:2.40.128.90 31 268 2.6E-32 T 13-10-2018 Spica_0719 5c500fbc85532965f17ac5faf10c6bc0 164 Pfam PF00665 Integrase core domain 15 125 2.0E-27 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Spica_0719 5c500fbc85532965f17ac5faf10c6bc0 164 SUPERFAMILY SSF53098 14 164 2.66E-43 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0719 5c500fbc85532965f17ac5faf10c6bc0 164 Gene3D G3DSA:3.30.420.10 10 158 3.2E-19 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_1206 413893d9e890db0fe932ba8b04f84fc0 292 Pfam PF01497 Periplasmic binding protein 44 270 2.5E-47 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain Spica_1206 413893d9e890db0fe932ba8b04f84fc0 292 Gene3D G3DSA:3.40.50.1980 41 161 6.4E-33 T 13-10-2018 Spica_1206 413893d9e890db0fe932ba8b04f84fc0 292 Gene3D G3DSA:3.40.50.1980 164 292 1.7E-40 T 13-10-2018 Spica_1206 413893d9e890db0fe932ba8b04f84fc0 292 SUPERFAMILY SSF53807 23 291 2.12E-70 T 13-10-2018 Spica_1056 8cf101f0d30b2515945013cfebec1377 317 Gene3D G3DSA:1.10.3720.10 54 315 4.4E-54 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1056 8cf101f0d30b2515945013cfebec1377 317 SUPERFAMILY SSF161098 57 303 2.49E-48 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1056 8cf101f0d30b2515945013cfebec1377 317 SUPERFAMILY SSF160964 13 46 4.97E-5 T 13-10-2018 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 SUPERFAMILY SSF57783 1 99 2.04E-35 T 13-10-2018 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 SMART SM00400 35 89 1.4E-28 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Pfam PF01807 CHC2 zinc finger 5 99 2.6E-36 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Hamap MF_00974 DNA primase [dnaG]. 3 588 25.809 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Gene3D G3DSA:3.90.980.10 111 240 1.9E-39 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Pfam PF13662 Toprim domain 260 335 3.0E-16 T 13-10-2018 IPR006171 TOPRIM domain Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 422 4.3E-128 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Gene3D G3DSA:3.40.1360.10 241 368 1.1E-35 T 13-10-2018 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 SUPERFAMILY SSF56731 117 428 2.49E-85 T 13-10-2018 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 250 6.7E-37 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 PIRSF PIRSF002811 1 598 2.9E-163 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 SMART SM00493 259 330 1.6E-13 T 13-10-2018 IPR006171 TOPRIM domain Spica_1393 558639aac8e1ae6045d5e3c9b80677d2 603 Gene3D G3DSA:3.90.580.10 2 100 5.8E-38 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 Spica_1028 00d2588e5478d3932572da5f5b729949 230 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 24 131 3.3E-32 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Spica_1028 00d2588e5478d3932572da5f5b729949 230 SMART SM00479 23 227 6.6E-44 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Spica_1028 00d2588e5478d3932572da5f5b729949 230 Pfam PF00929 Exonuclease 25 130 3.0E-26 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Spica_1028 00d2588e5478d3932572da5f5b729949 230 Pfam PF00929 Exonuclease 168 218 1.2E-7 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Spica_1028 00d2588e5478d3932572da5f5b729949 230 SUPERFAMILY SSF53098 24 226 4.28E-50 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0670 7dc18fa17038400fac213d4ff256bb00 376 Pfam PF04773 FecR protein 84 162 8.1E-8 T 13-10-2018 IPR006860 FecR protein Spica_1852 96a6bae952eb394d02fb64013b39874c 275 Gene3D G3DSA:3.40.50.1000 8 269 8.3E-58 T 13-10-2018 IPR023214 HAD superfamily Spica_1852 96a6bae952eb394d02fb64013b39874c 275 Gene3D G3DSA:3.30.1240.10 88 198 8.3E-58 T 13-10-2018 Spica_1852 96a6bae952eb394d02fb64013b39874c 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 266 1.5E-49 T 13-10-2018 Spica_1852 96a6bae952eb394d02fb64013b39874c 275 SUPERFAMILY SSF56784 4 273 5.63E-56 T 13-10-2018 IPR036412 HAD-like superfamily Spica_1852 96a6bae952eb394d02fb64013b39874c 275 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 10 269 7.6E-46 T 13-10-2018 IPR000150 Cof family GO:0016787 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 Gene3D G3DSA:1.25.10.10 461 639 3.5E-27 T 13-10-2018 IPR011989 Armadillo-like helical Spica_2556 619a2af7b34b743181939f73a42a6b48 788 Gene3D G3DSA:1.20.1250.20 18 205 2.1E-5 T 13-10-2018 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 Gene3D G3DSA:1.20.1250.20 230 432 1.1E-17 T 13-10-2018 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 SUPERFAMILY SSF103473 23 428 3.79E-30 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_2556 619a2af7b34b743181939f73a42a6b48 788 Pfam PF13646 HEAT repeats 482 567 3.4E-15 T 13-10-2018 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 SMART SM00567 E-Z type HEAT repeats 524 553 0.0028 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 SMART SM00567 E-Z type HEAT repeats 556 586 130.0 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 SMART SM00567 E-Z type HEAT repeats 493 522 2.2E-4 T 13-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 Spica_2556 619a2af7b34b743181939f73a42a6b48 788 SUPERFAMILY SSF48371 475 638 4.68E-18 T 13-10-2018 IPR016024 Armadillo-type fold Spica_1878 b8f21f46d0a899a0ea973d8c0917956c 311 Pfam PF04754 Putative transposase, YhgA-like 3 199 1.3E-28 T 13-10-2018 IPR006842 Transposase (putative), YhgA-like Spica_0622 57c64dbdcddd84f11039b0abd445fd18 269 Gene3D G3DSA:1.10.3720.10 1 260 5.5E-71 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0622 57c64dbdcddd84f11039b0abd445fd18 269 SUPERFAMILY SSF161098 3 268 7.1E-75 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0622 57c64dbdcddd84f11039b0abd445fd18 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 261 3.0E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0095 92c3a16c36415932b8d8e54c265ad631 391 Pfam PF13635 Domain of unknown function (DUF4143) 178 337 1.3E-26 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Spica_0095 92c3a16c36415932b8d8e54c265ad631 391 SUPERFAMILY SSF52540 16 140 3.25E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0095 92c3a16c36415932b8d8e54c265ad631 391 Pfam PF13173 AAA domain 21 137 4.2E-25 T 13-10-2018 Spica_1019 0099075adb2e6522bfe971a80bd62134 644 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 397 543 2.2E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1019 0099075adb2e6522bfe971a80bd62134 644 SUPERFAMILY SSF58104 251 614 1.1E-42 T 13-10-2018 Spica_1019 0099075adb2e6522bfe971a80bd62134 644 Gene3D G3DSA:1.10.287.950 295 615 7.4E-44 T 13-10-2018 Spica_1019 0099075adb2e6522bfe971a80bd62134 644 SMART SM00283 326 601 5.7E-24 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1019 0099075adb2e6522bfe971a80bd62134 644 SMART SM00304 231 283 0.0094 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_1134 f29698ece506eea9c9af239c1a2f5c83 271 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 151 259 7.5E-30 T 13-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Spica_1134 f29698ece506eea9c9af239c1a2f5c83 271 Gene3D G3DSA:3.10.270.10 7 263 1.0E-97 T 13-10-2018 Spica_1134 f29698ece506eea9c9af239c1a2f5c83 271 Pfam PF02649 Type I GTP cyclohydrolase folE2 9 258 1.3E-98 T 13-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Spica_1134 f29698ece506eea9c9af239c1a2f5c83 271 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 9 263 36.342 T 13-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 Spica_2070 b10c20fc328b53c62df8066241524097 478 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 14 453 4.6E-76 T 13-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 Spica_2070 b10c20fc328b53c62df8066241524097 478 Gene3D G3DSA:1.20.1250.20 12 416 3.4E-25 T 13-10-2018 Spica_2070 b10c20fc328b53c62df8066241524097 478 SUPERFAMILY SSF103473 4 441 2.09E-32 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_2070 b10c20fc328b53c62df8066241524097 478 Pfam PF13347 MFS/sugar transport protein 15 441 2.3E-83 T 13-10-2018 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 10 304 37.91 T 13-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 PIRSF PIRSF000164 1 304 3.4E-69 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 Gene3D G3DSA:3.20.20.70 6 306 7.6E-90 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 SUPERFAMILY SSF51395 7 302 1.72E-79 T 13-10-2018 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 Pfam PF01180 Dihydroorotate dehydrogenase 10 291 2.3E-63 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Spica_2554 b504d1dbbe6cfc929907746149bfea18 308 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 10 302 3.3E-100 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Spica_2855 418cfeda8a332e973253f913ef78d332 125 Pfam PF06803 Protein of unknown function (DUF1232) 34 70 4.8E-14 T 13-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 Spica_1743 5c7dcf71d14c2c107ab0bafb1f6dc61d 243 Gene3D G3DSA:3.60.60.10 1 238 1.4E-8 T 13-10-2018 Spica_1666 9de68fbbc236073853b5d1f696b990e0 149 Pfam PF02050 Flagellar FliJ protein 21 137 4.1E-16 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 Spica_1666 9de68fbbc236073853b5d1f696b990e0 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 137 4.2E-24 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 SMART SM00283 324 571 8.9E-55 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 389 551 1.4E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 Gene3D G3DSA:1.10.287.950 326 571 5.1E-51 T 13-10-2018 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 Gene3D G3DSA:1.20.1480.50 184 287 3.5E-11 T 13-10-2018 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 SMART SM00304 229 281 9.4E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 Pfam PF00672 HAMP domain 230 276 4.0E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0846 da7171b593d2b0944827d79de8a3489e 662 SUPERFAMILY SSF58104 249 579 1.83E-51 T 13-10-2018 Spica_0222 305f9c2a990818f34da3ea813052615a 163 Pfam PF02810 SEC-C motif 143 161 4.0E-11 T 13-10-2018 IPR004027 SEC-C motif Spica_0222 305f9c2a990818f34da3ea813052615a 163 Pfam PF02810 SEC-C motif 3 17 1.0E-4 T 13-10-2018 IPR004027 SEC-C motif Spica_0222 305f9c2a990818f34da3ea813052615a 163 SUPERFAMILY SSF54427 24 129 4.56E-32 T 13-10-2018 IPR032710 NTF2-like domain superfamily Spica_0222 305f9c2a990818f34da3ea813052615a 163 SUPERFAMILY SSF103642 140 161 4.09E-9 T 13-10-2018 Spica_0222 305f9c2a990818f34da3ea813052615a 163 Gene3D G3DSA:3.10.450.50 1 162 2.5E-53 T 13-10-2018 Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 SMART SM01152 8 84 9.1E-26 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 13 81 7.6E-23 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 96 16.752 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 Gene3D G3DSA:3.30.1200.10 2 94 5.3E-26 T 13-10-2018 IPR036591 YggU-like superfamily Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 6 80 4.1E-15 T 13-10-2018 IPR005228 Conserved hypothetical protein CHP00251 Spica_1155 bcc65c422caebb6e885421fec48a1fd7 99 SUPERFAMILY SSF69786 4 83 6.54E-24 T 13-10-2018 IPR036591 YggU-like superfamily Spica_0210 50d89f1e8115e787f9761e364782a2fa 291 SUPERFAMILY SSF161098 20 282 1.83E-60 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0210 50d89f1e8115e787f9761e364782a2fa 291 Gene3D G3DSA:1.10.3720.10 11 280 1.3E-59 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0210 50d89f1e8115e787f9761e364782a2fa 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 279 1.0E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0110 82fb2da2b125074c5512395662dbf5ea 455 Pfam PF01841 Transglutaminase-like superfamily 317 432 1.6E-9 T 13-10-2018 IPR002931 Transglutaminase-like Spica_0110 82fb2da2b125074c5512395662dbf5ea 455 Gene3D G3DSA:3.10.620.30 307 402 3.7E-11 T 13-10-2018 Spica_0110 82fb2da2b125074c5512395662dbf5ea 455 SUPERFAMILY SSF54001 315 396 8.41E-14 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Spica_2002 3a164efbf39d47a2389e7f9c6a1633fc 231 SMART SM00382 30 217 1.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_2002 3a164efbf39d47a2389e7f9c6a1633fc 231 Pfam PF00005 ABC transporter 21 169 1.7E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2002 3a164efbf39d47a2389e7f9c6a1633fc 231 SUPERFAMILY SSF52540 1 223 2.66E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2002 3a164efbf39d47a2389e7f9c6a1633fc 231 Gene3D G3DSA:3.40.50.300 1 229 4.5E-60 T 13-10-2018 Spica_2002 3a164efbf39d47a2389e7f9c6a1633fc 231 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Spica_1472 8faca01a10af2ee5e878d9968a719275 153 Pfam PF10135 Rod binding protein 89 131 9.5E-14 T 13-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal Spica_2866 6cc9c5cd685d94eaf8941152a81b0f72 81 SUPERFAMILY SSF47598 3 39 1.19E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_2866 6cc9c5cd685d94eaf8941152a81b0f72 81 Gene3D G3DSA:1.10.1220.10 1 66 1.9E-6 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Spica_0881 356bade1f84e6856346b6a498522e220 377 Pfam PF13519 von Willebrand factor type A domain 236 344 6.9E-7 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_0881 356bade1f84e6856346b6a498522e220 377 Gene3D G3DSA:3.40.50.410 231 375 1.0E-12 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_0881 356bade1f84e6856346b6a498522e220 377 SUPERFAMILY SSF53300 230 352 2.23E-18 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1684 70e2455158c933a61bc1f5fb56ec78ac 381 Pfam PF01098 Cell cycle protein 20 371 6.5E-97 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1684 70e2455158c933a61bc1f5fb56ec78ac 381 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 18 371 3.1E-106 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 Gene3D G3DSA:1.10.3210.10 511 706 5.0E-22 T 13-10-2018 Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 Pfam PF07697 7TM-HD extracellular 55 298 7.8E-27 T 13-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 Pfam PF07698 7TM receptor with intracellular HD hydrolase 308 497 5.5E-19 T 13-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 SMART SM00471 518 672 4.1E-9 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 TIGRFAM TIGR00277 HDIG: HDIG domain 520 617 6.7E-29 T 13-10-2018 IPR006675 HDIG domain Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 SUPERFAMILY SSF109604 521 685 5.71E-19 T 13-10-2018 Spica_1228 aca20df1177767a4694a22af9d45d0f2 735 Pfam PF01966 HD domain 522 662 1.3E-19 T 13-10-2018 IPR006674 HD domain Spica_0713 bfa160e815f3df5b318b98a7ce402163 427 Gene3D G3DSA:3.40.190.10 22 427 8.0E-58 T 13-10-2018 Spica_0713 bfa160e815f3df5b318b98a7ce402163 427 SUPERFAMILY SSF53850 28 425 1.81E-54 T 13-10-2018 Spica_0713 bfa160e815f3df5b318b98a7ce402163 427 Pfam PF01547 Bacterial extracellular solute-binding protein 43 331 1.3E-33 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_1936 e71fe495abc3a6d9610693d2e9972cff 192 Pfam PF01641 SelR domain 56 174 2.8E-47 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Spica_1936 e71fe495abc3a6d9610693d2e9972cff 192 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 53 182 1.4E-57 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Spica_1936 e71fe495abc3a6d9610693d2e9972cff 192 Gene3D G3DSA:2.170.150.20 46 192 3.6E-57 T 13-10-2018 Spica_1936 e71fe495abc3a6d9610693d2e9972cff 192 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 41 175 34.792 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Spica_1936 e71fe495abc3a6d9610693d2e9972cff 192 SUPERFAMILY SSF51316 52 191 2.56E-58 T 13-10-2018 IPR011057 Mss4-like superfamily Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 Gene3D G3DSA:1.25.40.10 34 119 4.1E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 Pfam PF17170 6-bladed beta-propeller 205 275 4.0E-8 T 13-10-2018 Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 SUPERFAMILY SSF101898 153 401 3.66E-33 T 13-10-2018 Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 Gene3D G3DSA:2.120.10.30 120 231 1.6E-8 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 Gene3D G3DSA:2.120.10.30 232 413 6.8E-32 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 SUPERFAMILY SSF53300 545 628 7.63E-5 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1315 3b7adc56807be29c5ce9e59c6ab9449e 684 SUPERFAMILY SSF48452 43 118 5.27E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1067 9574ea76257410cde962050351dfd0b3 3676 SUPERFAMILY SSF103657 684 771 7.67E-5 T 13-10-2018 IPR027267 AH/BAR domain superfamily Spica_0433 7d0f9b4c9ff64ea8557bee713ec8f014 76 Gene3D G3DSA:2.30.31.70 1 75 9.2E-35 T 13-10-2018 Spica_0433 7d0f9b4c9ff64ea8557bee713ec8f014 76 PIRSF PIRSF037246 1 72 9.4E-36 T 13-10-2018 IPR017154 Uncharacterised conserved protein UCP037246 Spica_0433 7d0f9b4c9ff64ea8557bee713ec8f014 76 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 21 66 1.9E-11 T 13-10-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0006355 Spica_0112 4e6cdc4b818d1f1241e8175850f74674 250 SUPERFAMILY SSF81606 13 149 1.1E-5 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_1330 e208f8cd7960d2b3e3a9105fd611cfc7 115 SUPERFAMILY SSF81301 7 97 4.91E-8 T 13-10-2018 Spica_1330 e208f8cd7960d2b3e3a9105fd611cfc7 115 Gene3D G3DSA:3.30.460.10 1 100 1.3E-10 T 13-10-2018 Spica_0245 b0978d08662d7b3df2f2ba124a9dfa5d 148 Pfam PF00011 Hsp20/alpha crystallin family 47 146 1.3E-23 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Spica_0245 b0978d08662d7b3df2f2ba124a9dfa5d 148 SUPERFAMILY SSF49764 21 147 4.19E-38 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_0245 b0978d08662d7b3df2f2ba124a9dfa5d 148 Gene3D G3DSA:2.60.40.790 10 147 1.5E-38 T 13-10-2018 IPR008978 HSP20-like chaperone Spica_1833 292f0a75529dcd5649261bed59d9757a 122 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 25 106 2.0E-32 T 13-10-2018 IPR003849 Preprotein translocase YajC Spica_1833 292f0a75529dcd5649261bed59d9757a 122 PRINTS PR01853 Bacterial YajC preprotein translocase signature 26 46 9.6E-15 T 13-10-2018 IPR003849 Preprotein translocase YajC Spica_1833 292f0a75529dcd5649261bed59d9757a 122 PRINTS PR01853 Bacterial YajC preprotein translocase signature 64 82 9.6E-15 T 13-10-2018 IPR003849 Preprotein translocase YajC Spica_1833 292f0a75529dcd5649261bed59d9757a 122 SMART SM01323 24 106 2.5E-43 T 13-10-2018 IPR003849 Preprotein translocase YajC Spica_1833 292f0a75529dcd5649261bed59d9757a 122 Pfam PF02699 Preprotein translocase subunit 28 103 4.0E-30 T 13-10-2018 IPR003849 Preprotein translocase YajC Spica_2177 8e66b01f873700713a21f35e2822565f 460 Gene3D G3DSA:2.60.40.1180 29 458 6.4E-139 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2177 8e66b01f873700713a21f35e2822565f 460 PRINTS PR00843 Glycosyl hydrolase family 30 signature 38 58 3.4E-14 T 13-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 Spica_2177 8e66b01f873700713a21f35e2822565f 460 PRINTS PR00843 Glycosyl hydrolase family 30 signature 74 100 3.4E-14 T 13-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 Spica_2177 8e66b01f873700713a21f35e2822565f 460 PRINTS PR00843 Glycosyl hydrolase family 30 signature 168 185 3.4E-14 T 13-10-2018 IPR001139 Glycoside hydrolase family 30 GO:0004348|GO:0006665 Reactome: R-HSA-1660662|Reactome: R-HSA-390471 Spica_2177 8e66b01f873700713a21f35e2822565f 460 Pfam PF02055 Glycosyl hydrolase family 30 TIM-barrel domain 48 380 6.1E-66 T 13-10-2018 IPR033453 Glycosyl hydrolase family 30, TIM-barrel domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 Spica_2177 8e66b01f873700713a21f35e2822565f 460 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 383 457 4.4E-8 T 13-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 Spica_2177 8e66b01f873700713a21f35e2822565f 460 SUPERFAMILY SSF51445 48 384 3.33E-79 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2177 8e66b01f873700713a21f35e2822565f 460 Gene3D G3DSA:3.20.20.80 46 384 6.4E-139 T 13-10-2018 Spica_0178 ba8d0cf178cd04461716fdf414ddd76b 270 SUPERFAMILY SSF51366 5 236 4.8E-52 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_0178 ba8d0cf178cd04461716fdf414ddd76b 270 Pfam PF00290 Tryptophan synthase alpha chain 6 236 3.0E-49 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0178 ba8d0cf178cd04461716fdf414ddd76b 270 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 265 24.349 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_0178 ba8d0cf178cd04461716fdf414ddd76b 270 Gene3D G3DSA:3.20.20.70 2 243 3.2E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0178 ba8d0cf178cd04461716fdf414ddd76b 270 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 235 1.3E-47 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Spica_2856 ef34bbe2b42660ad86cf7a3e7e3fc7bf 273 Gene3D G3DSA:3.90.1010.20 151 273 4.3E-39 T 13-10-2018 Spica_2856 ef34bbe2b42660ad86cf7a3e7e3fc7bf 273 Gene3D G3DSA:3.90.1010.20 22 146 1.2E-43 T 13-10-2018 Spica_2629 2bc8f15c7b417cbbd7db459161c1858b 182 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 154 9.2E-24 T 13-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ Spica_0100 66c53f7e9d8b6b671c7b3a57343d5192 152 Pfam PF01850 PIN domain 3 136 1.5E-16 T 13-10-2018 IPR002716 PIN domain Spica_0100 66c53f7e9d8b6b671c7b3a57343d5192 152 Gene3D G3DSA:3.40.50.1010 2 130 2.2E-8 T 13-10-2018 Spica_0100 66c53f7e9d8b6b671c7b3a57343d5192 152 SUPERFAMILY SSF88723 3 140 3.6E-11 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1119 c99a46f6813a43019fe604d26e506639 365 SUPERFAMILY SSF109604 170 349 8.79E-33 T 13-10-2018 Spica_1119 c99a46f6813a43019fe604d26e506639 365 Pfam PF01966 HD domain 184 309 3.7E-19 T 13-10-2018 IPR006674 HD domain Spica_1119 c99a46f6813a43019fe604d26e506639 365 Gene3D G3DSA:1.10.3210.10 156 363 2.4E-66 T 13-10-2018 Spica_1119 c99a46f6813a43019fe604d26e506639 365 SMART SM00471 178 319 4.2E-8 T 13-10-2018 IPR003607 HD/PDEase domain Spica_1041 f18b23b1e09437d3d0ec2c2f81b6626f 293 SUPERFAMILY SSF53335 108 282 4.33E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1041 f18b23b1e09437d3d0ec2c2f81b6626f 293 Pfam PF13489 Methyltransferase domain 103 248 5.8E-25 T 13-10-2018 Spica_1041 f18b23b1e09437d3d0ec2c2f81b6626f 293 Gene3D G3DSA:3.40.50.150 98 258 1.0E-37 T 13-10-2018 Spica_2378 4baaf518d9d9d236bb5d926436ac0b01 327 Pfam PF13519 von Willebrand factor type A domain 86 196 2.8E-14 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_2378 4baaf518d9d9d236bb5d926436ac0b01 327 SMART SM00327 83 258 4.9E-12 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_2378 4baaf518d9d9d236bb5d926436ac0b01 327 Gene3D G3DSA:3.40.50.410 81 285 1.4E-41 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_2378 4baaf518d9d9d236bb5d926436ac0b01 327 SUPERFAMILY SSF53300 83 281 4.01E-23 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1191 129d080b5ca9d890f25e6f478ba824ae 314 SUPERFAMILY SSF55186 182 282 3.01E-5 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Spica_1191 129d080b5ca9d890f25e6f478ba824ae 314 SUPERFAMILY SSF52540 45 207 2.37E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0227 e9cc09db8ebf2a7a926fc4490307a585 591 Pfam PF03739 Predicted permease YjgP/YjgQ family 386 552 4.0E-7 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Spica_0973 ec268339a7986b1d5df32e0f557f17a6 257 ProSitePatterns PS01215 Mrp family signature. 121 137 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 Spica_0973 ec268339a7986b1d5df32e0f557f17a6 257 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 12 230 1.4E-81 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Spica_0973 ec268339a7986b1d5df32e0f557f17a6 257 Hamap MF_02040 Iron-sulfur cluster carrier protein. 6 253 33.457 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Spica_0973 ec268339a7986b1d5df32e0f557f17a6 257 Gene3D G3DSA:3.40.50.300 5 233 3.0E-68 T 13-10-2018 Spica_0973 ec268339a7986b1d5df32e0f557f17a6 257 SUPERFAMILY SSF52540 10 228 5.94E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1361 42a68c8c53a35edb32a324b257b8d7d5 354 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 349 5.0E-63 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Spica_1989 369cff11ecba5e9e9934e0b9a5506fd8 263 SUPERFAMILY SSF109604 48 174 1.08E-7 T 13-10-2018 Spica_1989 369cff11ecba5e9e9934e0b9a5506fd8 263 Gene3D G3DSA:1.10.3210.10 20 197 9.1E-8 T 13-10-2018 Spica_0469 120236f8c52326df6ac2a3e523b5873f 224 Gene3D G3DSA:1.10.10.10 129 174 3.9E-5 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0469 120236f8c52326df6ac2a3e523b5873f 224 Pfam PF02631 RecX family 107 190 2.6E-11 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 Spica_1459 ea51ba574427f56c0331c5fc8362409b 326 SUPERFAMILY SSF53448 5 244 1.73E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1459 ea51ba574427f56c0331c5fc8362409b 326 Gene3D G3DSA:3.90.550.10 1 272 1.5E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1459 ea51ba574427f56c0331c5fc8362409b 326 Pfam PF00535 Glycosyl transferase family 2 8 120 2.0E-25 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Spica_2076 e386238d6fb2db058a781189c9d62334 403 Gene3D G3DSA:1.10.10.10 3 89 2.9E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2076 e386238d6fb2db058a781189c9d62334 403 SUPERFAMILY SSF53067 95 395 5.13E-31 T 13-10-2018 Spica_2076 e386238d6fb2db058a781189c9d62334 403 Gene3D G3DSA:3.30.420.40 91 226 9.5E-27 T 13-10-2018 Spica_2076 e386238d6fb2db058a781189c9d62334 403 SUPERFAMILY SSF46785 11 65 2.81E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2076 e386238d6fb2db058a781189c9d62334 403 Gene3D G3DSA:3.30.420.40 227 375 1.7E-16 T 13-10-2018 Spica_2076 e386238d6fb2db058a781189c9d62334 403 Pfam PF00480 ROK family 97 293 5.1E-34 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 PIRSF PIRSF006078 1 377 1.9E-123 T 13-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 Pfam PF02595 Glycerate kinase family 3 372 2.0E-129 T 13-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 Gene3D G3DSA:3.90.1510.10 42 276 2.4E-124 T 13-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 SUPERFAMILY SSF110738 1 374 1.83E-112 T 13-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 373 6.8E-123 T 13-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 Spica_0250 86887c44a7ff47c2b54acb3121e97908 379 Gene3D G3DSA:3.40.50.10350 1 361 2.4E-124 T 13-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold Spica_0843 05b29bf2c7713cfd6f5362da2818d068 314 Gene3D G3DSA:3.40.630.30 82 312 6.4E-25 T 13-10-2018 Spica_0843 05b29bf2c7713cfd6f5362da2818d068 314 Pfam PF08445 FR47-like protein 246 306 1.7E-14 T 13-10-2018 IPR013653 FR47-like GO:0016747 Spica_0843 05b29bf2c7713cfd6f5362da2818d068 314 SUPERFAMILY SSF55729 117 311 1.56E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_1505 189906950b5b06faff75766b922a5ac7 204 Gene3D G3DSA:1.20.5.620 3 65 4.0E-5 T 13-10-2018 Spica_1505 189906950b5b06faff75766b922a5ac7 204 SUPERFAMILY SSF160527 84 197 2.22E-7 T 13-10-2018 Spica_2591 765039070421590df6b6f995e2707390 232 SMART SM00855 21 184 1.2E-19 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_2591 765039070421590df6b6f995e2707390 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 23 212 2.3E-37 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_2591 765039070421590df6b6f995e2707390 232 SUPERFAMILY SSF53254 21 220 2.88E-41 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Spica_2591 765039070421590df6b6f995e2707390 232 Gene3D G3DSA:3.40.50.1240 17 223 1.8E-42 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Spica_2591 765039070421590df6b6f995e2707390 232 PIRSF PIRSF000709 18 127 2.1E-5 T 13-10-2018 Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 265 2.7E-15 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 SUPERFAMILY SSF52540 1 292 5.85E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 Gene3D G3DSA:3.30.70.20 52 111 8.5E-15 T 13-10-2018 Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 SUPERFAMILY SSF54862 35 118 2.93E-20 T 13-10-2018 Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 Pfam PF14697 4Fe-4S dicluster domain 62 113 9.8E-10 T 13-10-2018 Spica_0705 56619c03e0ffa351953ce11400cd1ca1 299 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2454 56f38d0cbaf5b8c1dcaccd3342166af5 483 Gene3D G3DSA:3.40.190.10 156 383 2.7E-50 T 13-10-2018 Spica_2454 56f38d0cbaf5b8c1dcaccd3342166af5 483 SUPERFAMILY SSF53850 20 480 6.29E-85 T 13-10-2018 Spica_2454 56f38d0cbaf5b8c1dcaccd3342166af5 483 Gene3D G3DSA:3.40.190.10 34 155 7.0E-20 T 13-10-2018 Spica_2454 56f38d0cbaf5b8c1dcaccd3342166af5 483 Pfam PF01547 Bacterial extracellular solute-binding protein 56 345 1.3E-31 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0010 ea6684ec04eb156b1976d093c995b495 286 Gene3D G3DSA:1.20.1330.10 48 237 7.8E-57 T 13-10-2018 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 PRINTS PR00207 Flagellin signature 74 93 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 PRINTS PR00207 Flagellin signature 109 132 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 PRINTS PR00207 Flagellin signature 35 52 4.5E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.3E-40 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 SUPERFAMILY SSF64518 1 286 3.92E-84 T 13-10-2018 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 Gene3D G3DSA:1.10.8.410 238 286 1.7E-24 T 13-10-2018 Spica_0010 ea6684ec04eb156b1976d093c995b495 286 Pfam PF00700 Bacterial flagellin C-terminal helical region 201 285 6.6E-25 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1561 146905f6c86de9b4c93ce9d26a09c1c8 336 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 336 24.141 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Spica_1561 146905f6c86de9b4c93ce9d26a09c1c8 336 Pfam PF02654 Cobalamin-5-phosphate synthase 48 323 7.0E-34 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 Spica_1308 0d34c55cbcdd233db9cca3247bf996e9 211 Pfam PF02361 Cobalt transport protein 15 208 6.6E-10 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Spica_2734 b8cd57d1c228fa15a0c7cd4feb432c7a 108 Gene3D G3DSA:3.30.750.24 1 106 2.1E-19 T 13-10-2018 IPR036513 STAS domain superfamily Spica_2734 b8cd57d1c228fa15a0c7cd4feb432c7a 108 SUPERFAMILY SSF52091 4 106 7.46E-20 T 13-10-2018 IPR036513 STAS domain superfamily Spica_2734 b8cd57d1c228fa15a0c7cd4feb432c7a 108 Pfam PF01740 STAS domain 5 105 3.8E-13 T 13-10-2018 IPR002645 STAS domain Spica_2734 b8cd57d1c228fa15a0c7cd4feb432c7a 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 105 1.0E-16 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spica_1048 936fdc2c2ae8a8804067d32584fddcff 224 Pfam PF00849 RNA pseudouridylate synthase 13 146 4.0E-30 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1048 936fdc2c2ae8a8804067d32584fddcff 224 Gene3D G3DSA:3.30.2350.10 4 211 6.5E-58 T 13-10-2018 Spica_1048 936fdc2c2ae8a8804067d32584fddcff 224 SUPERFAMILY SSF55120 3 209 1.06E-59 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_1048 936fdc2c2ae8a8804067d32584fddcff 224 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 49 63 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Spica_2782 d63ae7852f302a95a3aa31c238758d81 111 Gene3D G3DSA:3.40.1390.20 2 101 2.8E-8 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2782 d63ae7852f302a95a3aa31c238758d81 111 SUPERFAMILY SSF75138 1 108 1.44E-12 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_1064 3a0e4dc35d7e36c2689dd810162444ba 520 Pfam PF13205 Bacterial Ig-like domain 275 353 1.6E-7 T 13-10-2018 IPR032812 SbsA, Ig-like domain Spica_1064 3a0e4dc35d7e36c2689dd810162444ba 520 Gene3D G3DSA:2.60.40.1220 277 359 1.8E-5 T 13-10-2018 Spica_0815 2fc6207abfcc792431edeabab8ef8f9c 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 31.66 T 13-10-2018 IPR023064 D-ribose pyranase GO:0016872 Spica_0815 2fc6207abfcc792431edeabab8ef8f9c 131 Pfam PF05025 RbsD / FucU transport protein family 1 129 1.9E-46 T 13-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_0815 2fc6207abfcc792431edeabab8ef8f9c 131 Gene3D G3DSA:3.40.1650.10 8 128 1.1E-36 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_0815 2fc6207abfcc792431edeabab8ef8f9c 131 SUPERFAMILY SSF102546 1 131 1.83E-43 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 Spica_0140 fdb99d35469c2cac47accb34c51db383 179 Pfam PF07456 Heptaprenyl diphosphate synthase component I 14 158 2.4E-32 T 13-10-2018 IPR010898 Heptaprenyl diphosphate synthase component I Spica_0140 fdb99d35469c2cac47accb34c51db383 179 Gene3D G3DSA:1.10.1760.20 3 167 7.6E-6 T 13-10-2018 Spica_0140 fdb99d35469c2cac47accb34c51db383 179 PIRSF PIRSF027391 1 178 5.2E-28 T 13-10-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I Spica_0050 90ebf485bc0ef0629563e0b876f41c44 287 Gene3D G3DSA:3.40.50.1110 40 277 2.7E-53 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Spica_0050 90ebf485bc0ef0629563e0b876f41c44 287 SUPERFAMILY SSF52266 38 262 1.42E-36 T 13-10-2018 Spica_2090 11ba9af0dcb253429cc9333835951a8f 420 Gene3D G3DSA:3.40.50.1970 25 202 4.0E-37 T 13-10-2018 Spica_2090 11ba9af0dcb253429cc9333835951a8f 420 Pfam PF00465 Iron-containing alcohol dehydrogenase 47 409 1.4E-76 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Spica_2090 11ba9af0dcb253429cc9333835951a8f 420 SUPERFAMILY SSF56796 41 416 2.88E-74 T 13-10-2018 Spica_2090 11ba9af0dcb253429cc9333835951a8f 420 Gene3D G3DSA:1.20.1090.10 203 418 1.1E-40 T 13-10-2018 Spica_1949 28e1c9f9e3b26016b005144251a16aba 494 Gene3D G3DSA:3.40.50.2000 191 344 7.4E-6 T 13-10-2018 Spica_1949 28e1c9f9e3b26016b005144251a16aba 494 Gene3D G3DSA:3.40.50.2000 1 190 4.9E-6 T 13-10-2018 Spica_1949 28e1c9f9e3b26016b005144251a16aba 494 SUPERFAMILY SSF53756 3 307 4.14E-19 T 13-10-2018 Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 SUPERFAMILY SSF63411 55 260 2.17E-38 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 Gene3D G3DSA:3.30.830.10 58 267 4.6E-39 T 13-10-2018 Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 Pfam PF05193 Peptidase M16 inactive domain 221 357 2.3E-9 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 Gene3D G3DSA:3.30.830.10 278 478 6.3E-28 T 13-10-2018 Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 SUPERFAMILY SSF63411 271 477 1.03E-17 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Spica_0144 f57f8d0011e57e7682e961a835e2309f 492 Pfam PF00675 Insulinase (Peptidase family M16) 69 202 2.0E-7 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Spica_1096 e9782f940a9213f6cffa523bdfa8acd9 228 Pfam PF03006 Haemolysin-III related 23 221 1.4E-34 T 13-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 Spica_1096 e9782f940a9213f6cffa523bdfa8acd9 228 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 23 226 3.3E-57 T 13-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 Spica_1418 15ddc0e199a509e4408a80e99e7bf415 233 Gene3D G3DSA:3.40.1180.10 1 231 4.6E-86 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Spica_1418 15ddc0e199a509e4408a80e99e7bf415 233 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 6 229 1.2E-74 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Spica_1418 15ddc0e199a509e4408a80e99e7bf415 233 SUPERFAMILY SSF64005 6 225 6.28E-78 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Spica_1418 15ddc0e199a509e4408a80e99e7bf415 233 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 6 230 37.919 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Spica_1418 15ddc0e199a509e4408a80e99e7bf415 233 Pfam PF01255 Putative undecaprenyl diphosphate synthase 13 229 3.7E-73 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 124 136 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 158 169 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 204 231 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 63 81 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 298 315 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 353 366 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 277 292 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 260 275 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 PRINTS PR00992 Alanine racemase signature 27 43 5.8E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 Pfam PF01168 Alanine racemase, N-terminal domain 8 230 4.9E-63 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 SUPERFAMILY SSF51419 8 245 7.71E-62 T 13-10-2018 IPR029066 PLP-binding barrel Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 SMART SM01005 244 371 2.3E-59 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 TIGRFAM TIGR00492 alr: alanine racemase 4 372 3.8E-103 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 Pfam PF00842 Alanine racemase, C-terminal domain 244 370 5.7E-43 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 SUPERFAMILY SSF50621 238 371 6.63E-43 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 Gene3D G3DSA:2.40.37.10 233 372 3.2E-50 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 Hamap MF_01201 Alanine racemase. 1 371 32.298 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Spica_2499 2b1318a991a0ea110c213c615bdb37fc 372 Gene3D G3DSA:3.20.20.10 10 232 7.3E-69 T 13-10-2018 IPR029066 PLP-binding barrel Spica_1117 1446811e0fd3e2c8671c471d1e556deb 149 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 140 25.836 T 13-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 Spica_1117 1446811e0fd3e2c8671c471d1e556deb 149 SUPERFAMILY SSF141457 1 142 5.62E-43 T 13-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily Spica_1117 1446811e0fd3e2c8671c471d1e556deb 149 Gene3D G3DSA:2.30.290.10 1 147 6.9E-52 T 13-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily Spica_1117 1446811e0fd3e2c8671c471d1e556deb 149 Pfam PF02623 FliW protein 19 137 4.9E-42 T 13-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 Spica_0704 4aeb4ab132a6dc46058affabf8a938ef 113 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 105 3.8E-12 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Spica_0704 4aeb4ab132a6dc46058affabf8a938ef 113 Gene3D G3DSA:3.30.420.130 1 113 1.2E-24 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_0704 4aeb4ab132a6dc46058affabf8a938ef 113 SUPERFAMILY SSF53146 1 111 7.33E-22 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_2254 91c97bb8d583781636be2ca652d9544f 425 Pfam PF13679 Methyltransferase domain 175 316 1.4E-31 T 13-10-2018 IPR025714 Methyltransferase domain Spica_2254 91c97bb8d583781636be2ca652d9544f 425 Gene3D G3DSA:3.40.50.150 166 326 3.3E-12 T 13-10-2018 Spica_2254 91c97bb8d583781636be2ca652d9544f 425 SUPERFAMILY SSF53335 174 317 2.41E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2618 f05ffd2b24091d4771865a32683db7da 264 SUPERFAMILY SSF53850 9 263 5.85E-67 T 13-10-2018 Spica_2618 f05ffd2b24091d4771865a32683db7da 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 263 4.9E-62 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2618 f05ffd2b24091d4771865a32683db7da 264 SMART SM00062 44 264 2.3E-64 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2618 f05ffd2b24091d4771865a32683db7da 264 Gene3D G3DSA:3.40.190.10 45 263 9.3E-70 T 13-10-2018 Spica_2618 f05ffd2b24091d4771865a32683db7da 264 Gene3D G3DSA:3.40.190.10 130 222 9.3E-70 T 13-10-2018 Spica_2618 f05ffd2b24091d4771865a32683db7da 264 SMART SM00079 44 264 0.0068 T 13-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 Spica_1701 f19108de99ced74f2e6ec7bc12b6842a 106 Pfam PF05164 Cell division protein ZapA 7 88 1.6E-8 T 13-10-2018 IPR007838 Cell division protein ZapA-like Spica_1701 f19108de99ced74f2e6ec7bc12b6842a 106 SUPERFAMILY SSF102829 7 86 8.37E-9 T 13-10-2018 IPR036192 Cell division protein ZapA-like superfamily Spica_2595 4edb7d7ab91686ba5977ec957157081e 393 Pfam PF01963 TraB family 9 228 1.1E-29 T 13-10-2018 IPR002816 Pheromone shutdown, TraB Spica_2595 4edb7d7ab91686ba5977ec957157081e 393 TIGRFAM TIGR00261 traB: TraB family protein 12 390 2.6E-108 T 13-10-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal Spica_1685 c5901a546a28debff629bf4fb55aefe4 359 ProSitePatterns PS01348 MraY family signature 2. 188 199 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1685 c5901a546a28debff629bf4fb55aefe4 359 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 358 3.2E-131 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1685 c5901a546a28debff629bf4fb55aefe4 359 Pfam PF00953 Glycosyl transferase family 4 99 283 2.0E-39 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Spica_1685 c5901a546a28debff629bf4fb55aefe4 359 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1685 c5901a546a28debff629bf4fb55aefe4 359 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 357 24.939 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_0212 148898404ccb58699c6c5b4f6e47c1e8 434 SUPERFAMILY SSF53850 24 429 6.29E-50 T 13-10-2018 Spica_0212 148898404ccb58699c6c5b4f6e47c1e8 434 Pfam PF13416 Bacterial extracellular solute-binding protein 45 345 1.4E-22 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0212 148898404ccb58699c6c5b4f6e47c1e8 434 Gene3D G3DSA:3.40.190.10 22 434 7.1E-59 T 13-10-2018 Spica_0631 499134475ca6907883f49f9d11c31d93 318 Gene3D G3DSA:1.20.1530.20 10 315 1.4E-55 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Spica_0631 499134475ca6907883f49f9d11c31d93 318 Pfam PF01758 Sodium Bile acid symporter family 44 213 1.0E-22 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Spica_0155 b7512eb1d5eea31ace14b76d136e317b 163 Pfam PF04008 Adenosine specific kinase 8 161 1.8E-72 T 13-10-2018 IPR007153 Adenosine specific kinase Spica_0155 b7512eb1d5eea31ace14b76d136e317b 163 SUPERFAMILY SSF103165 3 162 1.7E-68 T 13-10-2018 IPR036902 Ta1353-like superfamily Spica_0155 b7512eb1d5eea31ace14b76d136e317b 163 Gene3D G3DSA:3.40.1520.10 1 162 6.9E-73 T 13-10-2018 IPR036902 Ta1353-like superfamily Spica_0251 ed99e755a3469e4c9ebbb8ef743f28b6 385 Pfam PF05651 Putative sugar diacid recognition 6 138 2.5E-37 T 13-10-2018 IPR008599 Putative sugar diacid recognition Spica_0251 ed99e755a3469e4c9ebbb8ef743f28b6 385 Gene3D G3DSA:1.10.10.2840 284 369 1.2E-9 T 13-10-2018 Spica_0251 ed99e755a3469e4c9ebbb8ef743f28b6 385 Pfam PF13556 PucR C-terminal helix-turn-helix domain 320 366 2.5E-14 T 13-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain Spica_1539 d1f481de601aab85adf91259cd0839d7 430 Gene3D G3DSA:3.30.750.140 276 390 5.6E-11 T 13-10-2018 IPR038610 FliK-like, C-terminal domain superfamily Spica_1539 d1f481de601aab85adf91259cd0839d7 430 Pfam PF02120 Flagellar hook-length control protein FliK 302 377 1.6E-15 T 13-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal Spica_0999 7ccc2b99632c2ecf790be8e475a3c3cb 291 Pfam PF01875 Memo-like protein 17 287 9.9E-37 T 13-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 Spica_0999 7ccc2b99632c2ecf790be8e475a3c3cb 291 Gene3D G3DSA:3.40.830.10 13 290 6.3E-42 T 13-10-2018 Spica_0999 7ccc2b99632c2ecf790be8e475a3c3cb 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 15 288 1.2E-67 T 13-10-2018 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 Pfam PF00403 Heavy-metal-associated domain 4 63 9.6E-16 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 PRINTS PR00944 Copper ion binding protein signature 51 64 7.0E-6 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 PRINTS PR00944 Copper ion binding protein signature 27 40 7.0E-6 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 PRINTS PR00944 Copper ion binding protein signature 2 14 7.0E-6 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 SUPERFAMILY SSF55008 1 65 9.69E-20 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Spica_2519 d75e4c1dfd056565a6c8386e013ce83e 69 Gene3D G3DSA:3.30.70.100 3 67 4.4E-23 T 13-10-2018 Spica_1728 259ee0421da3ad6f9e70f69daf960378 111 Gene3D G3DSA:3.30.390.50 1 88 3.6E-20 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 SUPERFAMILY SSF51735 1 337 7.04E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_1469 cd5f8712b419385dc919653452212880 341 PRINTS PR01713 Nucleotide sugar epimerase signature 298 315 3.5E-24 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 PRINTS PR01713 Nucleotide sugar epimerase signature 30 46 3.5E-24 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 PRINTS PR01713 Nucleotide sugar epimerase signature 233 248 3.5E-24 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 PRINTS PR01713 Nucleotide sugar epimerase signature 259 274 3.5E-24 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 Gene3D G3DSA:3.90.25.10 197 331 4.7E-100 T 13-10-2018 Spica_1469 cd5f8712b419385dc919653452212880 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 265 1.5E-56 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Spica_1469 cd5f8712b419385dc919653452212880 341 Gene3D G3DSA:3.40.50.720 5 319 4.7E-100 T 13-10-2018 Spica_0193 de48b18fe2dc44781a5dda48ac45cbf6 89 Gene3D G3DSA:3.30.70.120 1 88 5.8E-15 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_2196 9816ced8e66166964ae932cd0c4a7045 342 Pfam PF14903 WG containing repeat 73 109 1.1E-5 T 13-10-2018 IPR032774 WG containing repeat Spica_2196 9816ced8e66166964ae932cd0c4a7045 342 Pfam PF14903 WG containing repeat 179 204 5.1E-5 T 13-10-2018 IPR032774 WG containing repeat Spica_2196 9816ced8e66166964ae932cd0c4a7045 342 Pfam PF14903 WG containing repeat 109 139 0.0027 T 13-10-2018 IPR032774 WG containing repeat Spica_2196 9816ced8e66166964ae932cd0c4a7045 342 Pfam PF14903 WG containing repeat 38 71 4.4E-6 T 13-10-2018 IPR032774 WG containing repeat Spica_2196 9816ced8e66166964ae932cd0c4a7045 342 Pfam PF14903 WG containing repeat 161 179 0.0085 T 13-10-2018 IPR032774 WG containing repeat Spica_0621 0d744382a1aa318c1f90c56b80003783 297 Gene3D G3DSA:1.10.3720.10 54 295 1.1E-71 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0621 0d744382a1aa318c1f90c56b80003783 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 288 2.0E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0621 0d744382a1aa318c1f90c56b80003783 297 SUPERFAMILY SSF161098 60 285 2.35E-62 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0373 5809d1e23f3a94876c6ded4cbc7ecb8a 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 6 60 9.8E-18 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Spica_0373 5809d1e23f3a94876c6ded4cbc7ecb8a 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 59 5.8E-17 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0373 5809d1e23f3a94876c6ded4cbc7ecb8a 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 3 58 12.438 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Spica_0373 5809d1e23f3a94876c6ded4cbc7ecb8a 60 Gene3D G3DSA:1.20.5.1030 1 59 5.5E-18 T 13-10-2018 IPR038379 SecE superfamily Spica_0441 5b380bdba153b9a28e60269a9c7d006e 262 Pfam PF01066 CDP-alcohol phosphatidyltransferase 80 148 1.2E-10 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Spica_0441 5b380bdba153b9a28e60269a9c7d006e 262 Gene3D G3DSA:1.20.120.1760 75 250 5.6E-11 T 13-10-2018 Spica_0594 23fa9757749474b80483d420ec47355a 164 SUPERFAMILY SSF56524 22 113 6.15E-11 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 Gene3D G3DSA:3.30.1490.150 117 185 2.1E-55 T 13-10-2018 Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 SUPERFAMILY SSF143447 4 192 5.49E-58 T 13-10-2018 IPR036071 AMMECR1 domain superfamily Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 Pfam PF01871 AMMECR1 17 187 3.9E-48 T 13-10-2018 IPR002733 AMMECR1 domain Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 Gene3D G3DSA:3.30.700.20 9 192 2.1E-55 T 13-10-2018 IPR027485 AMMECR1, N-terminal Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 52 193 8.5E-39 T 13-10-2018 IPR023473 AMMECR1 Spica_0986 41db7309e0778d0277ad4bd25773e56d 194 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 12 189 5.0E-50 T 13-10-2018 IPR027623 AmmeMemoRadiSam system protein A Spica_1821 a51a32f513da68dbe17f9cb8116aa459 336 SUPERFAMILY SSF103486 24 332 2.35E-18 T 13-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1821 a51a32f513da68dbe17f9cb8116aa459 336 Pfam PF01992 ATP synthase (C/AC39) subunit 32 325 1.9E-25 T 13-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Pfam PF13581 Histidine kinase-like ATPase domain 455 544 9.7E-10 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Pfam PF02743 Cache domain 37 250 5.5E-14 T 13-10-2018 IPR033479 Double Cache domain 1 Spica_2426 5265ab79616530384949acf9b7f54d6c 551 SMART SM00387 454 551 3.2E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Pfam PF07568 Histidine kinase 361 434 9.1E-25 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Gene3D G3DSA:3.30.450.20 302 412 5.1E-10 T 13-10-2018 Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Gene3D G3DSA:3.30.450.20 75 164 1.4E-8 T 13-10-2018 Spica_2426 5265ab79616530384949acf9b7f54d6c 551 Gene3D G3DSA:3.30.565.10 418 551 1.7E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2426 5265ab79616530384949acf9b7f54d6c 551 SUPERFAMILY SSF55874 422 549 1.27E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1820 c4676dcf8b18b2f63e8c3d01190d246c 675 Pfam PF01496 V-type ATPase 116kDa subunit family 264 387 1.5E-17 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1820 c4676dcf8b18b2f63e8c3d01190d246c 675 Pfam PF01496 V-type ATPase 116kDa subunit family 558 669 1.7E-13 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1820 c4676dcf8b18b2f63e8c3d01190d246c 675 Gene3D G3DSA:3.30.70.2750 138 207 6.2E-7 T 13-10-2018 Spica_1820 c4676dcf8b18b2f63e8c3d01190d246c 675 Gene3D G3DSA:1.20.1460.20 47 274 6.2E-7 T 13-10-2018 Spica_1820 c4676dcf8b18b2f63e8c3d01190d246c 675 Gene3D G3DSA:3.30.70.2170 7 295 6.2E-7 T 13-10-2018 Spica_0960 caac052a93a5d7f0ac4a13381f491366 154 Pfam PF13690 Chemotaxis phosphatase CheX 42 137 4.9E-19 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain Spica_0960 caac052a93a5d7f0ac4a13381f491366 154 Gene3D G3DSA:3.40.1550.10 1 154 2.4E-43 T 13-10-2018 IPR028976 CheC-like superfamily Spica_0960 caac052a93a5d7f0ac4a13381f491366 154 SUPERFAMILY SSF103039 1 150 1.96E-35 T 13-10-2018 IPR028976 CheC-like superfamily Spica_2095 869fff07d581e4541d60699541b0b799 430 SUPERFAMILY SSF109604 272 421 5.34E-25 T 13-10-2018 Spica_2095 869fff07d581e4541d60699541b0b799 430 Pfam PF01966 HD domain 280 383 7.1E-13 T 13-10-2018 IPR006674 HD domain Spica_2095 869fff07d581e4541d60699541b0b799 430 Gene3D G3DSA:1.10.3210.10 212 430 1.1E-59 T 13-10-2018 Spica_2261 4602b8dbf0a38b32ccc988269f8e1c66 271 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 36 266 3.4E-84 T 13-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 Spica_2261 4602b8dbf0a38b32ccc988269f8e1c66 271 SUPERFAMILY SSF110710 10 270 1.15E-91 T 13-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like Spica_1030 1e34ea0467ee59034d76435e63cffad4 85 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 9 83 3.8E-17 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 Spica_1030 1e34ea0467ee59034d76435e63cffad4 85 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 9 81 1.4E-16 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 Spica_1896 7d8a4cf7eddbb74baabee68de278d618 293 SUPERFAMILY SSF161098 55 281 6.8E-51 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1896 7d8a4cf7eddbb74baabee68de278d618 293 Gene3D G3DSA:1.10.3720.10 51 292 9.2E-56 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1896 7d8a4cf7eddbb74baabee68de278d618 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 289 4.6E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0963 1ad6a7ce187c3e3cc5e128192e785440 309 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 49 309 3.6E-26 T 13-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA Spica_2045 edd6711b118a2db5f20317cbbf52a28c 364 SUPERFAMILY SSF56300 27 215 4.64E-13 T 13-10-2018 Spica_2045 edd6711b118a2db5f20317cbbf52a28c 364 Gene3D G3DSA:3.60.21.10 22 241 2.8E-6 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 ProSitePatterns PS00194 Thioredoxin family active site. 32 50 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 SUPERFAMILY SSF52833 8 116 1.42E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 TIGRFAM TIGR01068 thioredoxin: thioredoxin 18 114 1.6E-34 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 Pfam PF00085 Thioredoxin 28 112 2.4E-26 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 PIRSF PIRSF000077 1 115 2.1E-31 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 PRINTS PR00421 Thioredoxin family signature 39 48 1.3E-7 T 13-10-2018 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 PRINTS PR00421 Thioredoxin family signature 31 39 1.3E-7 T 13-10-2018 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 PRINTS PR00421 Thioredoxin family signature 79 90 1.3E-7 T 13-10-2018 Spica_1316 a69f8121d2b64ce8c4e563d7c73b45b3 121 Gene3D G3DSA:3.40.30.10 1 120 2.9E-35 T 13-10-2018 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 SUPERFAMILY SSF46894 154 220 2.04E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 2.3E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 2.3E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 2.3E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 Gene3D G3DSA:3.40.50.12740 2 221 8.0E-67 T 13-10-2018 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 1.5E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 SMART SM00421 158 215 2.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 Pfam PF00072 Response regulator receiver domain 5 116 1.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 SUPERFAMILY SSF52172 1 131 7.97E-35 T 13-10-2018 IPR011006 CheY-like superfamily Spica_0123 e9ed50d5826813a9aad9a64148a10954 221 SMART SM00448 2 115 1.4E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2613 de0b1cffab931b35a57e701c58153309 346 Gene3D G3DSA:3.20.20.70 50 193 4.3E-9 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2613 de0b1cffab931b35a57e701c58153309 346 SUPERFAMILY SSF102114 59 172 2.94E-9 T 13-10-2018 Spica_2613 de0b1cffab931b35a57e701c58153309 346 Pfam PF04055 Radical SAM superfamily 59 180 1.2E-7 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_2613 de0b1cffab931b35a57e701c58153309 346 ProSitePatterns PS01087 Radical activating enzymes signature. 52 73 - T 13-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 Spica_1312 b0c5cf28681d87030a62933e67d01611 566 Gene3D G3DSA:3.60.110.10 302 534 2.5E-13 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1312 b0c5cf28681d87030a62933e67d01611 566 Pfam PF00795 Carbon-nitrogen hydrolase 355 525 4.2E-18 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Spica_1312 b0c5cf28681d87030a62933e67d01611 566 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 3 546 17.209 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Spica_1312 b0c5cf28681d87030a62933e67d01611 566 SUPERFAMILY SSF56317 303 526 1.96E-33 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1312 b0c5cf28681d87030a62933e67d01611 566 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 132 506 7.0E-79 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Pfam PF00364 Biotin-requiring enzyme 5 76 1.1E-14 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Gene3D G3DSA:2.40.50.100 2 98 5.5E-24 T 13-10-2018 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Pfam PF02817 e3 binding domain 115 149 2.2E-11 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Gene3D G3DSA:3.30.559.10 214 460 5.7E-68 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 SUPERFAMILY SSF47005 112 152 3.53E-9 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 SUPERFAMILY SSF52777 223 462 6.23E-62 T 13-10-2018 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Gene3D G3DSA:4.10.320.10 112 155 9.4E-12 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 227 462 1.3E-64 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 SUPERFAMILY SSF51230 1 87 1.83E-21 T 13-10-2018 IPR011053 Single hybrid motif Spica_1982 8b9b2442e4aa67c063a9caab7645617e 464 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 Pfam PF00209 Sodium:neurotransmitter symporter family 146 443 2.4E-26 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 Pfam PF00209 Sodium:neurotransmitter symporter family 15 124 2.7E-24 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 SUPERFAMILY SSF161070 5 445 6.28E-119 T 13-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 1.5E-11 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 1.5E-11 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2738 ec32c1f206f556da200a537e1394f5e6 450 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 298 317 1.5E-11 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 Pfam PF13533 Biotin-lipoyl like 70 113 8.0E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 286 310 4.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 354 369 4.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 35 58 4.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 310 333 4.7E-9 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Spica_2185 570ce59dd9d3956ddaf4a4eb33d0ec8c 383 Pfam PF13437 HlyD family secretion protein 239 341 1.7E-14 T 13-10-2018 Spica_1512 815fa33b293b995502040be3c5c4532b 161 Pfam PF02674 Colicin V production protein 6 144 3.1E-22 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 Spica_0084 36b455d43133751ae75349572dee1a4a 371 SUPERFAMILY SSF53335 15 325 2.79E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0084 36b455d43133751ae75349572dee1a4a 371 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 19 327 1.3E-19 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_0084 36b455d43133751ae75349572dee1a4a 371 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 245 251 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Spica_0084 36b455d43133751ae75349572dee1a4a 371 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 69 82 3.5E-5 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_0084 36b455d43133751ae75349572dee1a4a 371 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 242 254 3.5E-5 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_0084 36b455d43133751ae75349572dee1a4a 371 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 19 35 3.5E-5 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Spica_1907 1b14b44e68f84551cf604f3aa4edd585 294 Gene3D G3DSA:1.10.3720.10 17 285 1.0E-62 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1907 1b14b44e68f84551cf604f3aa4edd585 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 282 1.3E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_1907 1b14b44e68f84551cf604f3aa4edd585 294 SUPERFAMILY SSF161098 26 294 4.32E-69 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 SMART SM00859 4 105 2.6E-15 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 3 309 1.2E-126 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 309 51.408 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 SUPERFAMILY SSF51735 1 135 2.04E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 SUPERFAMILY SSF55347 116 290 2.45E-34 T 13-10-2018 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 Gene3D G3DSA:3.30.360.10 120 294 2.2E-31 T 13-10-2018 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 45 101 3.9E-10 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Spica_2812 2496c61a8b103e57e9dc4a5b98ee96f4 315 Gene3D G3DSA:3.40.50.720 2 119 9.7E-14 T 13-10-2018 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 SMART SM00487 140 409 0.0016 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 Pfam PF13307 Helicase C-terminal domain 630 791 5.3E-37 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 Gene3D G3DSA:3.40.50.300 142 411 6.9E-42 T 13-10-2018 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 SMART SM00491 646 778 3.5E-32 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 SUPERFAMILY SSF52540 164 771 5.58E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 68 73 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 Gene3D G3DSA:3.40.50.300 614 802 1.3E-34 T 13-10-2018 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 Gene3D G3DSA:3.40.140.10 5 95 3.9E-5 T 13-10-2018 Spica_1615 acb344f9809bd7ebf84fbd9c877b4edd 813 Pfam PF04002 RadC-like JAB domain 9 92 9.1E-6 T 13-10-2018 IPR025657 RadC-like JAB domain Spica_2477 82c38bb4a42d26cc2aaefb86c295e9eb 118 Gene3D G3DSA:3.30.70.120 2 116 3.9E-43 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_2477 82c38bb4a42d26cc2aaefb86c295e9eb 118 Pfam PF02641 Uncharacterized ACR, COG1993 9 104 4.4E-39 T 13-10-2018 IPR003793 Domain of unknown function DUF190 Spica_2477 82c38bb4a42d26cc2aaefb86c295e9eb 118 SUPERFAMILY SSF54913 8 105 6.67E-34 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_1693 7f3d5bf63d7d43ad8c0899eef0758fcf 250 Pfam PF04620 Flagellar filament outer layer protein Flaa 80 223 1.8E-26 T 13-10-2018 IPR006714 Flagellar filament outer layer protein FlaA GO:0030288|GO:0071973 Spica_0386 de4669a242ee67c7450094302fb5678c 213 Pfam PF00573 Ribosomal protein L4/L1 family 16 202 1.5E-60 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Spica_0386 de4669a242ee67c7450094302fb5678c 213 Gene3D G3DSA:3.40.1370.10 1 206 3.7E-69 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0386 de4669a242ee67c7450094302fb5678c 213 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.574 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0386 de4669a242ee67c7450094302fb5678c 213 SUPERFAMILY SSF52166 1 206 6.93E-68 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Spica_0386 de4669a242ee67c7450094302fb5678c 213 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 202 6.0E-67 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Spica_0945 1e1ce1d996c351b04c04822c3c22cff5 213 Pfam PF03975 CheD chemotactic sensory transduction 84 178 3.1E-27 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Spica_0945 1e1ce1d996c351b04c04822c3c22cff5 213 Gene3D G3DSA:3.30.1330.200 12 188 1.9E-44 T 13-10-2018 IPR038592 CheD-like superfamily Spica_0945 1e1ce1d996c351b04c04822c3c22cff5 213 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 8 182 27.232 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Spica_0945 1e1ce1d996c351b04c04822c3c22cff5 213 SUPERFAMILY SSF64438 14 184 1.83E-42 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 PRINTS PR00107 Phosphocarrier protein signature 40 55 1.9E-10 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 PRINTS PR00107 Phosphocarrier protein signature 55 72 1.9E-10 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.9E-10 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 3.4E-20 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 41 56 - T 13-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 SUPERFAMILY SSF55594 3 84 1.83E-20 T 13-10-2018 IPR035895 HPr-like superfamily Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 Gene3D G3DSA:3.30.1340.10 1 86 2.4E-23 T 13-10-2018 IPR035895 HPr-like superfamily Spica_2249 b5df13dfd6bf13246be96f91d2079589 89 Pfam PF00381 PTS HPr component phosphorylation site 4 84 2.0E-22 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Spica_2136 3e25c8ab92a64a4a369ed8b72c532898 415 Pfam PF07690 Major Facilitator Superfamily 39 370 5.1E-18 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_2136 3e25c8ab92a64a4a369ed8b72c532898 415 Gene3D G3DSA:1.20.1250.20 220 411 1.1E-13 T 13-10-2018 Spica_2136 3e25c8ab92a64a4a369ed8b72c532898 415 Gene3D G3DSA:1.20.1250.20 10 209 2.1E-10 T 13-10-2018 Spica_2136 3e25c8ab92a64a4a369ed8b72c532898 415 SUPERFAMILY SSF103473 18 408 1.83E-33 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 Gene3D G3DSA:1.10.150.130 99 193 4.0E-22 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 Gene3D G3DSA:1.10.443.10 199 412 1.1E-58 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 SUPERFAMILY SSF56349 203 419 7.36E-44 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 105 190 5.3E-16 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 TIGRFAM TIGR02249 integrase_gron: integron integrase 104 423 1.7E-112 T 13-10-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 Spica_1730 920112dfbd2fcbb89fdcfcfa9b534aba 428 Pfam PF00589 Phage integrase family 209 409 9.5E-41 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Spica_0286 93ca17888013d7826feef52321268f4e 496 PIRSF PIRSF028991 1 496 5.5E-167 T 13-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted Spica_0286 93ca17888013d7826feef52321268f4e 496 SUPERFAMILY SSF51998 6 468 2.2E-67 T 13-10-2018 Spica_0286 93ca17888013d7826feef52321268f4e 496 Pfam PF11230 Protein of unknown function (DUF3029) 13 495 4.2E-211 T 13-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted Spica_0286 93ca17888013d7826feef52321268f4e 496 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 5 495 2.1E-206 T 13-10-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted Spica_2478 f59ecc3488eb448dddb695ff7e382cf4 138 Pfam PF02566 OsmC-like protein 34 133 2.5E-17 T 13-10-2018 IPR003718 OsmC/Ohr family Spica_2478 f59ecc3488eb448dddb695ff7e382cf4 138 SUPERFAMILY SSF82784 3 135 1.83E-33 T 13-10-2018 IPR036102 OsmC/Ohr superfamily Spica_2478 f59ecc3488eb448dddb695ff7e382cf4 138 Gene3D G3DSA:3.30.300.20 2 137 2.5E-35 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Spica_1495 f1c841f10e43da51f9bbf13a9120a49c 353 Gene3D G3DSA:3.40.50.2020 83 317 1.0E-38 T 13-10-2018 Spica_1495 f1c841f10e43da51f9bbf13a9120a49c 353 Pfam PF14681 Uracil phosphoribosyltransferase 88 313 5.6E-27 T 13-10-2018 Spica_1495 f1c841f10e43da51f9bbf13a9120a49c 353 SUPERFAMILY SSF53271 67 315 5.4E-33 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Spica_1260 279502d90ecdb421d4990e387e8240d3 487 Gene3D G3DSA:1.20.1730.10 20 484 1.4E-72 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily Spica_1260 279502d90ecdb421d4990e387e8240d3 487 Pfam PF00474 Sodium:solute symporter family 31 434 1.1E-55 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Spica_0689 3ad9aa15c29b1a8bd375ef13194235e5 104 Pfam PF01910 Thiamine-binding protein 13 102 1.3E-18 T 13-10-2018 IPR002767 Thiamine-binding protein Spica_0689 3ad9aa15c29b1a8bd375ef13194235e5 104 SUPERFAMILY SSF89957 12 103 3.92E-18 T 13-10-2018 IPR029756 MTH1187/YkoF-like Spica_0689 3ad9aa15c29b1a8bd375ef13194235e5 104 Gene3D G3DSA:3.30.70.930 7 104 1.7E-25 T 13-10-2018 IPR029756 MTH1187/YkoF-like Spica_0207 96ab728011aea85729be8d533296d5b7 394 Pfam PF07690 Major Facilitator Superfamily 237 387 6.8E-9 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_0207 96ab728011aea85729be8d533296d5b7 394 Pfam PF07690 Major Facilitator Superfamily 14 236 3.2E-18 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Spica_0207 96ab728011aea85729be8d533296d5b7 394 SUPERFAMILY SSF103473 7 388 4.58E-41 T 13-10-2018 IPR036259 MFS transporter superfamily Spica_0207 96ab728011aea85729be8d533296d5b7 394 Gene3D G3DSA:1.20.1250.20 3 185 2.4E-18 T 13-10-2018 Spica_0207 96ab728011aea85729be8d533296d5b7 394 Gene3D G3DSA:1.20.1250.20 201 392 7.1E-32 T 13-10-2018 Spica_1313 96a871d367d9cc319802671303450890 395 PIRSF PIRSF000530 7 386 1.7E-70 T 13-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 Pfam PF08544 GHMP kinases C terminal 284 360 2.7E-9 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain Spica_1313 96a871d367d9cc319802671303450890 395 Gene3D G3DSA:3.30.70.890 202 361 1.9E-85 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_1313 96a871d367d9cc319802671303450890 395 Pfam PF00288 GHMP kinases N terminal domain 116 178 1.2E-6 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Spica_1313 96a871d367d9cc319802671303450890 395 SUPERFAMILY SSF55060 205 368 6.12E-34 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_1313 96a871d367d9cc319802671303450890 395 Pfam PF10509 Galactokinase galactose-binding signature 18 59 2.3E-4 T 13-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00959 Mevalonate kinase family signature 27 51 5.4E-20 T 13-10-2018 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00959 Mevalonate kinase family signature 119 141 5.4E-20 T 13-10-2018 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00959 Mevalonate kinase family signature 332 349 5.4E-20 T 13-10-2018 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00473 Galactokinase signature 268 282 1.4E-10 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00473 Galactokinase signature 112 130 1.4E-10 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00473 Galactokinase signature 92 103 1.4E-10 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 PRINTS PR00473 Galactokinase signature 29 47 1.4E-10 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 Spica_1313 96a871d367d9cc319802671303450890 395 Gene3D G3DSA:3.30.230.10 24 201 1.9E-85 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1313 96a871d367d9cc319802671303450890 395 SUPERFAMILY SSF54211 18 203 6.22E-31 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 SUPERFAMILY SSF53383 11 431 5.45E-122 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 PIRSF PIRSF001434 3 432 4.1E-127 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 431 9.8E-136 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 11 431 6.1E-178 T 13-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 Gene3D G3DSA:3.90.1150.10 299 432 4.4E-52 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_1944 4a2320c1b4b4bf9d4ddfccdc7c49b9bd 432 Gene3D G3DSA:3.40.640.10 10 295 9.2E-94 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_1466 2787d021047053fe0e9d20dc833d31f1 375 SUPERFAMILY SSF53756 36 373 1.44E-70 T 13-10-2018 Spica_1466 2787d021047053fe0e9d20dc833d31f1 375 Pfam PF00534 Glycosyl transferases group 1 192 347 7.3E-31 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_1466 2787d021047053fe0e9d20dc833d31f1 375 Pfam PF13439 Glycosyltransferase Family 4 55 171 2.6E-12 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_1466 2787d021047053fe0e9d20dc833d31f1 375 Gene3D G3DSA:3.40.50.2000 8 182 2.5E-12 T 13-10-2018 Spica_1466 2787d021047053fe0e9d20dc833d31f1 375 Gene3D G3DSA:3.40.50.2000 183 374 2.6E-45 T 13-10-2018 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 Pfam PF00700 Bacterial flagellin C-terminal helical region 199 283 5.6E-25 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 SUPERFAMILY SSF64518 1 283 2.35E-81 T 13-10-2018 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 3.8E-40 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 PRINTS PR00207 Flagellin signature 109 132 5.1E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 PRINTS PR00207 Flagellin signature 35 52 5.1E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 PRINTS PR00207 Flagellin signature 74 93 5.1E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 Gene3D G3DSA:1.20.58.1830 3 31 9.2E-60 T 13-10-2018 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 Gene3D G3DSA:1.20.1330.10 43 182 9.2E-60 T 13-10-2018 Spica_1127 c9273ccc655ae6af31773a20ecf2855e 284 Gene3D G3DSA:1.10.8.410 230 283 1.5E-25 T 13-10-2018 Spica_1538 478954be8a0291623517036f9259ac5c 145 Pfam PF03963 Flagellar hook capping protein - N-terminal region 27 84 7.5E-20 T 13-10-2018 IPR005648 Flagellar hook capping protein Spica_0791 312900203b5ca135078632a204d80873 93 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 93 26.987 T 13-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 Spica_0791 312900203b5ca135078632a204d80873 93 Pfam PF04026 SpoVG 1 81 7.0E-37 T 13-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 Spica_0791 312900203b5ca135078632a204d80873 93 Gene3D G3DSA:3.30.1120.40 1 92 3.2E-37 T 13-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 Spica_0791 312900203b5ca135078632a204d80873 93 SUPERFAMILY SSF160537 1 82 3.4E-32 T 13-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 Spica_2155 8f4d0babec3d18663764042017a1ae19 151 SUPERFAMILY SSF46785 1 126 3.84E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2155 8f4d0babec3d18663764042017a1ae19 151 Gene3D G3DSA:3.30.1490.190 78 133 2.1E-9 T 13-10-2018 Spica_2155 8f4d0babec3d18663764042017a1ae19 151 Gene3D G3DSA:1.10.10.10 1 66 1.4E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2155 8f4d0babec3d18663764042017a1ae19 151 Pfam PF01475 Ferric uptake regulator family 1 121 1.1E-10 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Spica_1563 363bd1e09924a280ce2763119b00a2ee 396 Gene3D G3DSA:1.20.1090.10 187 392 1.3E-43 T 13-10-2018 Spica_1563 363bd1e09924a280ce2763119b00a2ee 396 SUPERFAMILY SSF56796 2 390 3.53E-100 T 13-10-2018 Spica_1563 363bd1e09924a280ce2763119b00a2ee 396 Gene3D G3DSA:3.40.50.1970 1 186 2.0E-51 T 13-10-2018 Spica_1563 363bd1e09924a280ce2763119b00a2ee 396 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 366 8.9E-92 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 Spica_0541 36996278b7f84659d96593ffd296382c 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 332 1.4E-21 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0980 39d369524a98e82db3c37817f58268b8 163 Gene3D G3DSA:2.40.128.520 23 163 3.0E-11 T 13-10-2018 Spica_0980 39d369524a98e82db3c37817f58268b8 163 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 27 156 2.1E-26 T 13-10-2018 IPR019223 Domain of unknown function DUF2147 Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 PRINTS PR00069 Aldo-keto reductase signature 113 131 6.6E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 PRINTS PR00069 Aldo-keto reductase signature 47 71 6.6E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 PRINTS PR00069 Aldo-keto reductase signature 144 161 6.6E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 Gene3D G3DSA:3.20.20.100 4 320 6.2E-92 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 Pfam PF00248 Aldo/keto reductase family 19 314 6.7E-65 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Spica_0741 ffcdb6a8ae315bc910c88d3f03667c00 326 SUPERFAMILY SSF51430 5 317 6.68E-82 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_1956 9721293c6239e56436d650c100d837ef 217 Pfam PF02589 LUD domain 20 211 5.0E-46 T 13-10-2018 IPR003741 LUD domain Spica_1956 9721293c6239e56436d650c100d837ef 217 PIRSF PIRSF020269 6 217 1.1E-71 T 13-10-2018 IPR009501 Uncharacterised conserved protein UCP020269 Spica_1956 9721293c6239e56436d650c100d837ef 217 SUPERFAMILY SSF100950 20 161 7.2E-7 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Spica_2770 7f1fc66bcdb6dcead5c6645e2c2aeb6a 273 Gene3D G3DSA:3.60.21.10 1 262 1.5E-77 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_2770 7f1fc66bcdb6dcead5c6645e2c2aeb6a 273 SUPERFAMILY SSF56300 1 255 3.84E-48 T 13-10-2018 Spica_2770 7f1fc66bcdb6dcead5c6645e2c2aeb6a 273 Pfam PF13277 YmdB-like protein 4 254 2.4E-73 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Spica_1387 bae249c8c3c6958244f55e0597fcb8c3 167 Pfam PF04093 rod shape-determining protein MreD 3 159 1.3E-12 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Spica_1387 bae249c8c3c6958244f55e0597fcb8c3 167 PIRSF PIRSF037497 3 167 2.7E-32 T 13-10-2018 IPR017225 Cell shape-determining protein MreD, predicted Spica_1387 bae249c8c3c6958244f55e0597fcb8c3 167 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 154 2.5E-18 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 Spica_2218 27edc852482d692b907f02bea5905eab 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 325 2.1E-39 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 Gene3D G3DSA:3.30.450.40 25 195 9.3E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 SMART SM00267 185 358 1.0E-45 T 13-10-2018 IPR000160 GGDEF domain Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 SUPERFAMILY SSF55073 201 358 8.63E-43 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 SUPERFAMILY SSF55781 27 194 6.76E-13 T 13-10-2018 Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 Gene3D G3DSA:3.30.70.270 196 359 2.8E-49 T 13-10-2018 Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 194 357 6.5E-50 T 13-10-2018 IPR000160 GGDEF domain Spica_0162 fc409611f8fc0864c930957eed4d1d37 360 Pfam PF00990 Diguanylate cyclase, GGDEF domain 197 354 7.4E-43 T 13-10-2018 IPR000160 GGDEF domain Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 Gene3D G3DSA:1.10.1740.10 3 95 3.2E-22 T 13-10-2018 Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 Pfam PF00128 Alpha amylase, catalytic domain 108 309 2.9E-39 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 Gene3D G3DSA:3.20.20.80 98 554 1.9E-197 T 13-10-2018 Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 SUPERFAMILY SSF51445 22 559 1.48E-113 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 Gene3D G3DSA:3.90.400.10 185 260 1.9E-197 T 13-10-2018 Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 SUPERFAMILY SSF51011 571 636 1.52E-5 T 13-10-2018 Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 Gene3D G3DSA:2.60.40.1180 564 638 5.9E-7 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Spica_2119 2fa02fd803ca161e2d5432b1274fbc8c 641 SMART SM00642 100 531 1.6E-29 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Spica_1224 d64915611078bfeaf064e5cae741d2e0 769 SUPERFAMILY SSF88713 554 766 2.18E-33 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1224 d64915611078bfeaf064e5cae741d2e0 769 Pfam PF01522 Polysaccharide deacetylase 558 682 3.5E-13 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spica_1224 d64915611078bfeaf064e5cae741d2e0 769 SUPERFAMILY SSF82171 33 442 6.15E-17 T 13-10-2018 Spica_1224 d64915611078bfeaf064e5cae741d2e0 769 Gene3D G3DSA:3.20.20.370 532 769 9.9E-34 T 13-10-2018 Spica_1388 392fd7110e15db104a8c3a6c57822645 286 PIRSF PIRSF038471 3 286 7.9E-53 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Spica_1388 392fd7110e15db104a8c3a6c57822645 286 Gene3D G3DSA:2.40.10.350 184 264 9.7E-40 T 13-10-2018 Spica_1388 392fd7110e15db104a8c3a6c57822645 286 Pfam PF04085 rod shape-determining protein MreC 123 276 1.5E-39 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Spica_1388 392fd7110e15db104a8c3a6c57822645 286 Gene3D G3DSA:2.40.10.340 121 275 9.7E-40 T 13-10-2018 Spica_1388 392fd7110e15db104a8c3a6c57822645 286 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 39 281 1.2E-46 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 Pfam PF13242 HAD-hyrolase-like 186 256 5.2E-20 T 13-10-2018 Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 SUPERFAMILY SSF56784 12 259 5.11E-64 T 13-10-2018 IPR036412 HAD-like superfamily Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 Gene3D G3DSA:3.40.50.1000 14 249 1.2E-78 T 13-10-2018 IPR023214 HAD superfamily Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 14 235 2.9E-46 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 Pfam PF13344 Haloacid dehalogenase-like hydrolase 14 114 3.5E-27 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spica_2679 ce8b31dd5181aa6cf921554b9037fd24 261 Gene3D G3DSA:3.40.50.1000 91 186 1.2E-78 T 13-10-2018 IPR023214 HAD superfamily Spica_2172 68bce747da1fc399ff23bee49651465b 315 Pfam PF04754 Putative transposase, YhgA-like 4 199 9.5E-31 T 13-10-2018 IPR006842 Transposase (putative), YhgA-like Spica_1578 cfce949758d522ce76d12a3804feed05 288 Pfam PF08340 Domain of unknown function (DUF1732) 205 288 3.7E-30 T 13-10-2018 IPR013551 Domain of unknown function DUF1732 Spica_1578 cfce949758d522ce76d12a3804feed05 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 8.7E-65 T 13-10-2018 IPR005229 Conserved hypothetical protein CHP00255 Spica_1578 cfce949758d522ce76d12a3804feed05 288 Pfam PF03755 YicC-like family, N-terminal region 1 152 2.8E-36 T 13-10-2018 IPR013527 YicC-like, N-terminal Spica_2396 8b3bacde525229782dca45bb007d5f37 69 Gene3D G3DSA:3.30.160.250 6 65 8.7E-7 T 13-10-2018 Spica_2396 8b3bacde525229782dca45bb007d5f37 69 SUPERFAMILY SSF143100 4 55 9.02E-10 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like Spica_1410 6e6e9db91cd2bc88785a4cf84d8c6878 267 SUPERFAMILY SSF117396 5 257 4.97E-74 T 13-10-2018 IPR036520 UPF0759 superfamily Spica_1410 6e6e9db91cd2bc88785a4cf84d8c6878 267 Pfam PF01904 Protein of unknown function DUF72 21 253 8.6E-60 T 13-10-2018 IPR002763 Protein of unknown function DUF72 Spica_1410 6e6e9db91cd2bc88785a4cf84d8c6878 267 Gene3D G3DSA:3.20.20.410 1 260 1.2E-87 T 13-10-2018 IPR036520 UPF0759 superfamily Spica_2005 c970741df38e2f633028c828a71b2d4c 255 Gene3D G3DSA:3.40.50.2300 1 126 4.1E-36 T 13-10-2018 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 Pfam PF00072 Response regulator receiver domain 8 117 3.0E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 Gene3D G3DSA:1.10.10.10 147 255 5.7E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2005 c970741df38e2f633028c828a71b2d4c 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 181 253 1.9E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 SUPERFAMILY SSF46894 153 254 1.76E-27 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 SMART SM00862 177 253 4.4E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 SMART SM00448 5 116 1.5E-39 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Spica_2005 c970741df38e2f633028c828a71b2d4c 255 SUPERFAMILY SSF52172 6 122 1.57E-38 T 13-10-2018 IPR011006 CheY-like superfamily Spica_2375 6f602a7c93852ef1498aefe9a656e5b7 179 SUPERFAMILY SSF160443 89 170 8.76E-15 T 13-10-2018 IPR036063 Smr domain superfamily Spica_2375 6f602a7c93852ef1498aefe9a656e5b7 179 SMART SM00463 88 171 1.7E-9 T 13-10-2018 IPR002625 Smr domain Spica_2375 6f602a7c93852ef1498aefe9a656e5b7 179 Gene3D G3DSA:3.30.1370.110 52 176 1.5E-19 T 13-10-2018 Spica_2375 6f602a7c93852ef1498aefe9a656e5b7 179 Pfam PF01713 Smr domain 91 171 1.6E-17 T 13-10-2018 IPR002625 Smr domain Spica_0445 fc46b03db28fd76ac03528df8953b223 234 SUPERFAMILY SSF52540 12 175 6.98E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0445 fc46b03db28fd76ac03528df8953b223 234 Gene3D G3DSA:3.40.50.300 10 219 1.5E-15 T 13-10-2018 Spica_1692 8ec810d8d02224b05051e9ada14bac15 239 Pfam PF04620 Flagellar filament outer layer protein Flaa 24 225 3.3E-51 T 13-10-2018 IPR006714 Flagellar filament outer layer protein FlaA GO:0030288|GO:0071973 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 SUPERFAMILY SSF48452 187 320 1.87E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 SUPERFAMILY SSF53955 563 715 2.31E-36 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_0362 5338e81dba2475e9c23270202ee0e249 739 Pfam PF01464 Transglycosylase SLT domain 572 684 6.8E-21 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 SMART SM00028 285 318 0.36 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 SMART SM00028 197 230 72.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 Gene3D G3DSA:1.25.40.10 78 353 4.8E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0362 5338e81dba2475e9c23270202ee0e249 739 Gene3D G3DSA:1.10.530.10 559 723 2.0E-37 T 13-10-2018 Spica_0593 a98211ead2627c9d07e21e0309ad34b6 285 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 32 248 1.9E-40 T 13-10-2018 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC Spica_0215 d7fbe1e1a50fbaea4420a0df9350dde5 77 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 43 2.2E-6 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_0215 d7fbe1e1a50fbaea4420a0df9350dde5 77 Gene3D G3DSA:3.40.1620.10 1 41 1.5E-6 T 13-10-2018 Spica_0215 d7fbe1e1a50fbaea4420a0df9350dde5 77 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 42 3.6E-6 T 13-10-2018 Spica_0215 d7fbe1e1a50fbaea4420a0df9350dde5 77 SUPERFAMILY SSF143120 4 43 4.84E-6 T 13-10-2018 IPR036165 YefM-like superfamily Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 204 226 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 Gene3D G3DSA:3.40.50.720 111 307 4.1E-134 T 13-10-2018 Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 337 6.0E-25 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 SUPERFAMILY SSF52283 12 143 1.62E-32 T 13-10-2018 Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 SUPERFAMILY SSF51735 111 308 1.18E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 307 1.2E-59 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 Gene3D G3DSA:3.40.50.720 13 330 4.1E-134 T 13-10-2018 Spica_0964 84b09d0ff838a806ac068cca95163e1c 356 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 233 249 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spica_0620 d108938130e70ca422ecaeac665cb248 412 Gene3D G3DSA:3.40.190.10 25 412 6.3E-74 T 13-10-2018 Spica_0620 d108938130e70ca422ecaeac665cb248 412 SUPERFAMILY SSF53850 26 411 1.84E-61 T 13-10-2018 Spica_0620 d108938130e70ca422ecaeac665cb248 412 Pfam PF13416 Bacterial extracellular solute-binding protein 48 343 7.3E-32 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 SUPERFAMILY SSF51445 151 683 3.79E-228 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Gene3D G3DSA:3.30.379.10 40 148 4.5E-16 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Gene3D G3DSA:3.20.20.80 149 480 1.4E-157 T 13-10-2018 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 460 681 1.2E-89 T 13-10-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Gene3D G3DSA:3.90.1330.10 481 684 4.6E-78 T 13-10-2018 IPR037054 Alpha-glucuronidase, C-terminal domain superfamily GO:0005576|GO:0045493|GO:0046559 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Pfam PF03648 Glycosyl hydrolase family 67 N-terminus 7 129 8.9E-12 T 13-10-2018 IPR005154 Alpha glucuronidase, N-terminal GO:0045493|GO:0046559 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 SUPERFAMILY SSF55545 32 149 5.76E-12 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 PIRSF PIRSF029900 2 684 1.7E-276 T 13-10-2018 IPR011395 Alpha glucuronidase GO:0005576|GO:0045493|GO:0046559 Spica_0602 53d1cf51c6cb1a60c81d53ce5dbd17e7 684 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 133 459 3.4E-151 T 13-10-2018 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 Gene3D G3DSA:3.60.40.10 181 421 1.3E-45 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 237 421 1.6E-28 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 SMART SM00331 207 422 2.7E-25 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 SUPERFAMILY SSF81606 220 418 2.09E-13 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 Gene3D G3DSA:3.10.580.10 47 180 3.0E-6 T 13-10-2018 Spica_0477 b00f41d6423a729859f938d92a3e8ef6 424 SUPERFAMILY SSF54631 53 191 1.52E-6 T 13-10-2018 Spica_1555 b8a5d073d9038a929a4c35e846bdf23f 227 Gene3D G3DSA:2.40.160.20 53 216 2.8E-7 T 13-10-2018 Spica_0016 631e87bd73d83e220fd6e1ba20c3e1b4 501 Gene3D G3DSA:1.10.3210.10 215 493 7.6E-67 T 13-10-2018 Spica_0016 631e87bd73d83e220fd6e1ba20c3e1b4 501 SUPERFAMILY SSF109604 229 465 1.62E-58 T 13-10-2018 Spica_0016 631e87bd73d83e220fd6e1ba20c3e1b4 501 SMART SM00471 325 500 0.0018 T 13-10-2018 IPR003607 HD/PDEase domain Spica_0016 631e87bd73d83e220fd6e1ba20c3e1b4 501 Pfam PF08668 HDOD domain 238 432 1.2E-56 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD Spica_0016 631e87bd73d83e220fd6e1ba20c3e1b4 501 TIGRFAM TIGR00277 HDIG: HDIG domain 330 430 9.3E-10 T 13-10-2018 IPR006675 HDIG domain Spica_2056 bcd5ab20ec3b51095e620d9622feeb35 246 SUPERFAMILY SSF55681 9 242 1.92E-61 T 13-10-2018 Spica_2056 bcd5ab20ec3b51095e620d9622feeb35 246 Gene3D G3DSA:3.30.930.10 7 243 6.5E-73 T 13-10-2018 Spica_2056 bcd5ab20ec3b51095e620d9622feeb35 246 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 155 2.2E-8 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Spica_1985 a90201e78a3daff5aa303a38123b0fbf 457 SUPERFAMILY SSF89550 43 364 9.22E-9 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_1985 a90201e78a3daff5aa303a38123b0fbf 457 Gene3D G3DSA:3.20.20.140 36 209 3.0E-8 T 13-10-2018 Spica_0365 4e2b88696cd21a0a157fb3fd1f98c4d0 436 Pfam PF02646 RmuC family 114 421 1.2E-78 T 13-10-2018 IPR003798 DNA recombination RmuC Spica_2853 dd0fb31fb2ea3b610dce53da45e9561b 405 Pfam PF01882 Protein of unknown function DUF58 215 298 6.8E-10 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Spica_1293 25bca0d9e9b6ab0726417e596fc75ac2 504 Pfam PF01973 Protein of unknown function DUF115 165 347 1.5E-18 T 13-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Spica_0276 a4f161eca995b00058bba33e65593d61 401 Pfam PF00691 OmpA family 297 392 1.7E-21 T 13-10-2018 IPR006665 OmpA-like domain Spica_0276 a4f161eca995b00058bba33e65593d61 401 Gene3D G3DSA:3.30.1330.60 259 401 4.4E-37 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_0276 a4f161eca995b00058bba33e65593d61 401 PRINTS PR01021 OMPA domain signature 342 358 6.6E-7 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spica_0276 a4f161eca995b00058bba33e65593d61 401 PRINTS PR01021 OMPA domain signature 297 319 6.6E-7 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spica_0276 a4f161eca995b00058bba33e65593d61 401 PRINTS PR01021 OMPA domain signature 327 342 6.6E-7 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Spica_0276 a4f161eca995b00058bba33e65593d61 401 SUPERFAMILY SSF103088 277 398 7.19E-31 T 13-10-2018 IPR036737 OmpA-like domain superfamily Spica_1498 72cbb6369103b4734f916facae441cb6 372 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 8 364 3.9E-98 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Spica_1498 72cbb6369103b4734f916facae441cb6 372 SUPERFAMILY SSF56014 285 352 7.48E-10 T 13-10-2018 Spica_1498 72cbb6369103b4734f916facae441cb6 372 PIRSF PIRSF004640 1 372 4.1E-114 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Spica_1498 72cbb6369103b4734f916facae441cb6 372 Gene3D G3DSA:3.20.20.20 1 270 4.5E-75 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Spica_1498 72cbb6369103b4734f916facae441cb6 372 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 8 371 27.871 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Spica_1498 72cbb6369103b4734f916facae441cb6 372 Pfam PF04551 GcpE protein 19 370 1.7E-108 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Spica_1498 72cbb6369103b4734f916facae441cb6 372 Gene3D G3DSA:3.30.413.10 279 372 5.2E-28 T 13-10-2018 Spica_0683 45081775cef8a4876002836dffcd8bfd 220 Gene3D G3DSA:3.30.420.130 95 204 5.8E-18 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_0683 45081775cef8a4876002836dffcd8bfd 220 Hamap MF_00674 UPF0251 protein . 2 99 24.154 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 Spica_0683 45081775cef8a4876002836dffcd8bfd 220 SUPERFAMILY SSF53146 106 205 7.98E-19 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily Spica_0683 45081775cef8a4876002836dffcd8bfd 220 Pfam PF02001 Protein of unknown function DUF134 3 95 8.2E-25 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 Spica_0683 45081775cef8a4876002836dffcd8bfd 220 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 115 203 2.0E-11 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis Spica_2802 15669d029f7895afe8a7fb4cf3069dc2 330 Gene3D G3DSA:3.40.50.2300 146 322 2.4E-76 T 13-10-2018 Spica_2802 15669d029f7895afe8a7fb4cf3069dc2 330 Gene3D G3DSA:3.40.50.2300 47 299 2.4E-76 T 13-10-2018 Spica_2802 15669d029f7895afe8a7fb4cf3069dc2 330 Pfam PF04392 ABC transporter substrate binding protein 36 326 5.1E-76 T 13-10-2018 IPR007487 ABC transporter, substrate-binding protein Spica_2802 15669d029f7895afe8a7fb4cf3069dc2 330 SUPERFAMILY SSF53822 44 288 4.35E-10 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0297 64df6fce773466d9b97d65fcd04bd901 391 SUPERFAMILY SSF144052 29 390 6.02E-48 T 13-10-2018 Spica_0297 64df6fce773466d9b97d65fcd04bd901 391 Pfam PF02073 Thermophilic metalloprotease (M29) 174 286 3.2E-6 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 Spica_0461 f7533449a6115847590e1bfa82d5c667 378 Gene3D G3DSA:1.10.260.40 1 94 4.9E-26 T 13-10-2018 Spica_0461 f7533449a6115847590e1bfa82d5c667 378 Pfam PF13413 Helix-turn-helix domain 7 67 5.4E-22 T 13-10-2018 Spica_1183 5bc90ac72a8c7328bcbf92247934ea07 89 SMART SM00834 1 41 4.4E-19 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spica_1183 5bc90ac72a8c7328bcbf92247934ea07 89 Pfam PF09723 Zinc ribbon domain 1 40 1.0E-19 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spica_1183 5bc90ac72a8c7328bcbf92247934ea07 89 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 2.3E-22 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 SUPERFAMILY SSF51735 11 263 9.24E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 1.5E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 Gene3D G3DSA:3.40.50.720 4 263 5.1E-52 T 13-10-2018 Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 6.1E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 6.1E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 6.1E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 a48d07a4b2ef2283b3cf4624929e3d4f 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 262 5.4E-36 T 13-10-2018 Spica_1106 d4842297def762c86de71e0bd9b1cfec 686 SUPERFAMILY SSF51998 131 665 2.08E-157 T 13-10-2018 Spica_1106 d4842297def762c86de71e0bd9b1cfec 686 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 129 669 4.7E-148 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 Spica_1106 d4842297def762c86de71e0bd9b1cfec 686 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 130 670 4.4E-176 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 Spica_1106 d4842297def762c86de71e0bd9b1cfec 686 Gene3D G3DSA:3.20.70.20 145 672 4.2E-116 T 13-10-2018 Spica_1106 d4842297def762c86de71e0bd9b1cfec 686 Pfam PF03477 ATP cone domain 4 101 1.0E-16 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Spica_2462 66627b32627484d7d30ce9866d695f22 302 SUPERFAMILY SSF55073 109 263 2.35E-13 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2462 66627b32627484d7d30ce9866d695f22 302 Gene3D G3DSA:3.30.70.1230 104 292 1.6E-11 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1375 62befcbef8dc529b222d821271182ce3 251 Hamap MF_01805 Segregation and condensation protein A [scpA]. 10 241 20.843 T 13-10-2018 IPR003768 Segregation and condensation protein A Spica_1375 62befcbef8dc529b222d821271182ce3 251 Pfam PF02616 Segregation and condensation protein ScpA 27 237 4.2E-30 T 13-10-2018 IPR003768 Segregation and condensation protein A Spica_2368 e6cc73bd9be7fba338a38352e8e51211 342 Pfam PF00294 pfkB family carbohydrate kinase 49 332 4.0E-40 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Spica_2368 e6cc73bd9be7fba338a38352e8e51211 342 Gene3D G3DSA:3.40.1190.20 8 327 1.1E-68 T 13-10-2018 IPR029056 Ribokinase-like Spica_2368 e6cc73bd9be7fba338a38352e8e51211 342 Gene3D G3DSA:3.30.1110.10 15 132 1.1E-68 T 13-10-2018 Spica_2368 e6cc73bd9be7fba338a38352e8e51211 342 SUPERFAMILY SSF53613 5 331 5.77E-53 T 13-10-2018 IPR029056 Ribokinase-like Spica_2368 e6cc73bd9be7fba338a38352e8e51211 342 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 286 299 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Spica_0064 d43fa7d101738cede199988b4fbfefeb 957 SUPERFAMILY SSF52540 250 486 1.33E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0064 d43fa7d101738cede199988b4fbfefeb 957 Pfam PF12705 PD-(D/E)XK nuclease superfamily 668 948 2.4E-27 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Spica_0064 d43fa7d101738cede199988b4fbfefeb 957 Gene3D G3DSA:3.90.320.10 658 883 4.2E-6 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Spica_0064 d43fa7d101738cede199988b4fbfefeb 957 SUPERFAMILY SSF52980 666 870 1.02E-5 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Spica_2648 d9ae8f0661367e14968d9458911cf8cc 283 Gene3D G3DSA:3.40.50.300 1 221 8.2E-43 T 13-10-2018 Spica_2648 d9ae8f0661367e14968d9458911cf8cc 283 Pfam PF00005 ABC transporter 18 155 8.8E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Spica_2648 d9ae8f0661367e14968d9458911cf8cc 283 SUPERFAMILY SSF52540 2 220 8.22E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2648 d9ae8f0661367e14968d9458911cf8cc 283 SMART SM00382 26 203 1.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Spica_0740 160b047459bce214b1c3ad7ef724ed05 309 Gene3D G3DSA:3.90.550.10 2 305 1.5E-98 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0740 160b047459bce214b1c3ad7ef724ed05 309 SUPERFAMILY SSF53448 7 290 1.64E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1607 374080443ab711e8ad5cb03c924d306d 73 SUPERFAMILY SSF48452 3 56 1.29E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1607 374080443ab711e8ad5cb03c924d306d 73 Gene3D G3DSA:1.25.40.10 1 72 9.7E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 Gene3D G3DSA:3.20.20.70 63 329 6.6E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 339 1.2E-88 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 SUPERFAMILY SSF102114 99 306 3.14E-13 T 13-10-2018 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 Pfam PF04055 Radical SAM superfamily 104 264 2.6E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 Gene3D G3DSA:1.10.150.530 4 60 6.8E-12 T 13-10-2018 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 PIRSF PIRSF006004 3 345 4.8E-102 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 Spica_1435 435623d67b1a6f782813779a0b51fa74 347 SMART SM00729 100 313 0.0032 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_1799 ddde7518d8bd671ed947ef21c2b0a9ea 280 SUPERFAMILY SSF102215 4 256 2.75E-26 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Spica_1799 ddde7518d8bd671ed947ef21c2b0a9ea 280 Pfam PF02633 Creatinine amidohydrolase 7 249 7.3E-35 T 13-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Spica_1799 ddde7518d8bd671ed947ef21c2b0a9ea 280 Gene3D G3DSA:3.40.50.10310 2 260 1.8E-40 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Spica_2086 42c06a313530aa8abd549f0b59c8ae02 167 Gene3D G3DSA:3.40.50.1010 1 121 2.9E-5 T 13-10-2018 Spica_2086 42c06a313530aa8abd549f0b59c8ae02 167 SUPERFAMILY SSF88723 2 127 6.73E-8 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2086 42c06a313530aa8abd549f0b59c8ae02 167 Pfam PF11848 Domain of unknown function (DUF3368) 117 163 2.0E-6 T 13-10-2018 IPR021799 Protein of unknown function DUF3368 Spica_2086 42c06a313530aa8abd549f0b59c8ae02 167 Pfam PF01850 PIN domain 7 111 2.6E-5 T 13-10-2018 IPR002716 PIN domain Spica_0327 8eb8c7e8a9ea9371b7f9d785c5222cb2 244 PIRSF PIRSF015601 1 242 3.0E-38 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0327 8eb8c7e8a9ea9371b7f9d785c5222cb2 244 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 236 3.2E-29 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0327 8eb8c7e8a9ea9371b7f9d785c5222cb2 244 Pfam PF04452 RNA methyltransferase 19 234 7.7E-39 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Spica_0327 8eb8c7e8a9ea9371b7f9d785c5222cb2 244 SUPERFAMILY SSF75217 74 236 5.23E-26 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Spica_0327 8eb8c7e8a9ea9371b7f9d785c5222cb2 244 Gene3D G3DSA:3.40.1280.10 8 241 3.5E-28 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_1126 d01c473dfd9894eb60923e5b302555e1 124 SUPERFAMILY SSF160214 47 123 1.14E-20 T 13-10-2018 IPR035924 FlaG-like superfamily Spica_1126 d01c473dfd9894eb60923e5b302555e1 124 Gene3D G3DSA:3.30.160.170 33 120 1.6E-14 T 13-10-2018 IPR035924 FlaG-like superfamily Spica_1126 d01c473dfd9894eb60923e5b302555e1 124 Pfam PF03646 FlaG protein 50 122 7.3E-21 T 13-10-2018 IPR005186 FlaG protein Spica_2277 81e39850217936ef38e3ab5a3f18aaaa 290 SUPERFAMILY SSF51430 8 283 8.9E-39 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_2277 81e39850217936ef38e3ab5a3f18aaaa 290 Pfam PF00248 Aldo/keto reductase family 30 204 2.2E-24 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Spica_2277 81e39850217936ef38e3ab5a3f18aaaa 290 Gene3D G3DSA:3.20.20.100 4 249 5.4E-40 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 216 387 9.8E-13 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 Gene3D G3DSA:3.40.50.150 190 386 2.2E-39 T 13-10-2018 Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 Gene3D G3DSA:3.40.50.150 74 143 2.4E-10 T 13-10-2018 Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 SUPERFAMILY SSF50249 8 64 9.14E-9 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 Gene3D G3DSA:2.40.50.140 4 73 8.5E-18 T 13-10-2018 Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 SUPERFAMILY SSF53335 66 387 3.64E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1269 90dc06121949cb94f829deb6bcd6b4b8 388 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 318 349 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site Spica_1794 97293d312e6da9a5c1ec70ea29f9fdb2 286 SUPERFAMILY SSF102705 47 278 2.35E-35 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Spica_1794 97293d312e6da9a5c1ec70ea29f9fdb2 286 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 50 265 1.7E-28 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spica_1794 97293d312e6da9a5c1ec70ea29f9fdb2 286 Gene3D G3DSA:3.40.1390.30 45 262 1.9E-30 T 13-10-2018 Spica_1794 97293d312e6da9a5c1ec70ea29f9fdb2 286 Gene3D G3DSA:3.40.1390.30 117 255 1.9E-30 T 13-10-2018 Spica_0065 3020a3fafeea90807027594512224700 416 Pfam PF16257 tagaturonate epimerase 5 378 7.9E-60 T 13-10-2018 IPR032586 Tagaturonate epimerase Spica_1168 e9058812a8d49a044d479959e4bc882c 527 Gene3D G3DSA:3.40.50.10490 97 292 6.0E-155 T 13-10-2018 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 SUPERFAMILY SSF53697 8 522 9.34E-146 T 13-10-2018 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 Pfam PF00342 Phosphoglucose isomerase 52 516 2.7E-122 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 Gene3D G3DSA:1.10.1390.10 495 523 1.7E-6 T 13-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 Gene3D G3DSA:3.40.50.10490 14 494 6.0E-155 T 13-10-2018 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 45 512 36.174 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 453 471 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 471 485 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 339 360 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 485 498 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 PRINTS PR00662 Glucose-6-phosphate isomerase signature 149 168 4.7E-42 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_1168 e9058812a8d49a044d479959e4bc882c 527 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 485 502 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Spica_0429 8836c3cd1bc2bfa0c557f4d5138c1a9c 317 Pfam PF03313 Serine dehydratase alpha chain 18 301 5.3E-76 T 13-10-2018 IPR005130 Serine dehydratase-like, alpha subunit Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 Gene3D G3DSA:1.10.1370.20 227 601 1.9E-121 T 13-10-2018 Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 Pfam PF01432 Peptidase family M3 339 580 1.3E-19 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 Gene3D G3DSA:1.20.140.70 29 176 6.2E-10 T 13-10-2018 Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 Pfam PF08439 Oligopeptidase F 120 179 1.7E-11 T 13-10-2018 IPR013647 Oligopeptidase F, N-terminal domain Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 9 593 4.2E-190 T 13-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 Spica_0492 d7b0bd9c8e037190df3011015530b4f3 602 SUPERFAMILY SSF55486 58 594 1.66E-83 T 13-10-2018 Spica_2385 697ac6105bab72070eb9ff192084e5ef 422 Pfam PF13416 Bacterial extracellular solute-binding protein 70 326 5.6E-7 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_2385 697ac6105bab72070eb9ff192084e5ef 422 SUPERFAMILY SSF53850 25 326 2.12E-15 T 13-10-2018 Spica_2385 697ac6105bab72070eb9ff192084e5ef 422 Gene3D G3DSA:3.40.190.10 28 373 6.5E-19 T 13-10-2018 Spica_0443 6c3aa1bfb6b78d2bdd82bb5688519489 95 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 77 1.2E-11 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 Spica_2585 cc2f54384ca0d16ab0f92f98df0dfffa 193 Pfam PF02659 Putative manganese efflux pump 30 188 1.2E-49 T 13-10-2018 IPR003810 Putative manganese efflux pump Spica_2585 cc2f54384ca0d16ab0f92f98df0dfffa 193 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 191 23.173 T 13-10-2018 IPR022929 Putative manganese efflux pump MntP Spica_2302 0dc41bd4e7e441f891d7aa05ae1ae9ed 139 Pfam PF01934 Protein of unknown function DUF86 22 129 7.0E-18 T 13-10-2018 IPR008201 Protein of unknown function DUF86 Spica_2302 0dc41bd4e7e441f891d7aa05ae1ae9ed 139 Gene3D G3DSA:1.20.120.580 9 136 1.8E-12 T 13-10-2018 IPR037038 Bsu32300-like superfamily Spica_1132 9530d8ea33e0571af6105ecd49ae6150 224 ProDom PD155205 TRANSMEMBRANE MEMBRANE TP0733 TP0126 40 223 8.0E-23 T 13-10-2018 Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 SUPERFAMILY SSF53686 4 309 1.7E-100 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 Gene3D G3DSA:3.40.50.1100 10 303 2.5E-123 T 13-10-2018 Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 308 6.5E-135 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 308 5.9E-140 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 Gene3D G3DSA:3.40.50.1100 48 149 2.5E-123 T 13-10-2018 Spica_2093 3f0480b78a184c428c872bf165ed7b0a 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 297 6.1E-68 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2294 f951fd05190acc85e257daafeea30a29 443 SUPERFAMILY SSF102114 51 207 4.19E-15 T 13-10-2018 Spica_2294 f951fd05190acc85e257daafeea30a29 443 SUPERFAMILY SSF47781 336 409 1.61E-10 T 13-10-2018 IPR010994 RuvA domain 2-like Spica_2294 f951fd05190acc85e257daafeea30a29 443 Gene3D G3DSA:3.20.20.70 65 201 2.4E-9 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_2294 f951fd05190acc85e257daafeea30a29 443 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 3 431 5.8E-158 T 13-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 Gene3D G3DSA:1.25.40.10 3 138 1.6E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SMART SM00028 5 38 160.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SMART SM00028 73 106 8.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SMART SM00028 140 173 8.6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SMART SM00028 39 72 72.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SMART SM00028 174 208 68.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 Pfam PF13176 Tetratricopeptide repeat 43 66 0.014 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 SUPERFAMILY SSF48452 7 204 2.84E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 Pfam PF13181 Tetratricopeptide repeat 175 206 0.086 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 Pfam PF13181 Tetratricopeptide repeat 79 104 0.015 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2497 4b24ab9f0169717a2459c69bcd0ba108 221 Gene3D G3DSA:1.25.40.10 139 216 1.4E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1061 d3e8f8d88318dc8111d85bf208a5e1fc 478 SUPERFAMILY SSF56954 16 459 1.83E-39 T 13-10-2018 Spica_1061 d3e8f8d88318dc8111d85bf208a5e1fc 478 Pfam PF02321 Outer membrane efflux protein 42 221 3.7E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Spica_1824 faf7bfb8c307b5921d0b7d25751ae2e9 122 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 2.9E-10 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spica_1824 faf7bfb8c307b5921d0b7d25751ae2e9 122 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 2.9E-10 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spica_1824 faf7bfb8c307b5921d0b7d25751ae2e9 122 Pfam PF03840 Preprotein translocase SecG subunit 7 74 4.3E-17 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spica_1824 faf7bfb8c307b5921d0b7d25751ae2e9 122 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 75 4.5E-19 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Spica_2664 13a6225f7ee9ee1dee8fbbdd555ac43d 112 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 110 7.6E-24 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Spica_2664 13a6225f7ee9ee1dee8fbbdd555ac43d 112 SUPERFAMILY SSF50118 5 111 1.96E-33 T 13-10-2018 Spica_2664 13a6225f7ee9ee1dee8fbbdd555ac43d 112 Gene3D G3DSA:2.30.30.110 2 112 4.1E-42 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spica_2039 b0f9c9e9f714f8419be1adf19bc14e17 141 Pfam PF07977 FabA-like domain 8 130 2.6E-23 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Spica_2039 b0f9c9e9f714f8419be1adf19bc14e17 141 SUPERFAMILY SSF54637 2 136 3.55E-38 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_2039 b0f9c9e9f714f8419be1adf19bc14e17 141 Gene3D G3DSA:3.10.129.10 1 139 2.3E-43 T 13-10-2018 Spica_1678 61940104a61ba385f496bc248761fd1f 299 SUPERFAMILY SSF102405 84 282 2.59E-37 T 13-10-2018 Spica_1678 61940104a61ba385f496bc248761fd1f 299 Pfam PF02481 DNA recombination-mediator protein A 74 278 1.3E-68 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Spica_1678 61940104a61ba385f496bc248761fd1f 299 Gene3D G3DSA:3.40.50.450 9 291 3.0E-82 T 13-10-2018 Spica_1678 61940104a61ba385f496bc248761fd1f 299 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 70 286 9.8E-68 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 Spica_2657 a46039158aacae92a3ef2191278c4170 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 331 6.6E-27 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0040 f67187f5d526caaed754615c749c0eb0 346 Gene3D G3DSA:2.70.70.10 183 339 3.7E-46 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0040 f67187f5d526caaed754615c749c0eb0 346 SUPERFAMILY SSF51261 207 335 7.85E-50 T 13-10-2018 IPR011055 Duplicated hybrid motif Spica_0040 f67187f5d526caaed754615c749c0eb0 346 Pfam PF01551 Peptidase family M23 235 331 1.0E-31 T 13-10-2018 IPR016047 Peptidase M23 Spica_1976 f0d7c8bb386dd4dd7d68eb89f0dd87eb 687 TIGRFAM TIGR03545 TIGR03545: TIGR03545 family protein 85 621 1.1E-55 T 13-10-2018 IPR019934 Conserved hypothetical protein CHP03545 Spica_0054 ee9c6147ac26269be48078639ecd0446 475 SMART SM00656 164 410 3.3E-40 T 13-10-2018 IPR002022 Pectate lyase Spica_0054 ee9c6147ac26269be48078639ecd0446 475 Gene3D G3DSA:2.160.20.10 57 472 3.3E-105 T 13-10-2018 IPR012334 Pectin lyase fold Spica_0054 ee9c6147ac26269be48078639ecd0446 475 Pfam PF00544 Pectate lyase 192 404 2.2E-44 T 13-10-2018 IPR002022 Pectate lyase Spica_0054 ee9c6147ac26269be48078639ecd0446 475 SUPERFAMILY SSF51126 82 471 7.16E-66 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_0755 047687d78e989a61b259e33345415359 184 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 32 69 9.5E-10 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_0755 047687d78e989a61b259e33345415359 184 SUPERFAMILY SSF52374 30 182 4.86E-16 T 13-10-2018 Spica_0755 047687d78e989a61b259e33345415359 184 Gene3D G3DSA:3.40.50.620 29 179 3.1E-28 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0755 047687d78e989a61b259e33345415359 184 Pfam PF01467 Cytidylyltransferase-like 33 163 4.1E-5 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 Gene3D G3DSA:3.30.420.40 3 223 1.7E-43 T 13-10-2018 Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 SUPERFAMILY SSF53067 2 102 1.25E-25 T 13-10-2018 Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 SUPERFAMILY SSF53067 107 219 9.32E-5 T 13-10-2018 Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 Gene3D G3DSA:3.30.420.40 94 184 1.7E-43 T 13-10-2018 Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 Pfam PF00814 Glycoprotease family 29 129 1.9E-21 T 13-10-2018 IPR000905 Gcp-like domain Spica_1120 bb8036c4dcfe0f9387438a325e0e3b55 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 221 2.8E-42 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 Spica_1467 79c1a2e7f172824be88912482a51598b 359 Pfam PF13524 Glycosyl transferases group 1 267 349 2.9E-6 T 13-10-2018 Spica_1467 79c1a2e7f172824be88912482a51598b 359 SUPERFAMILY SSF53756 230 332 6.17E-5 T 13-10-2018 Spica_2777 f3768e0415b88e48b44fd0a2a5a3a935 165 PIRSF PIRSF000216 6 165 5.1E-48 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_2777 f3768e0415b88e48b44fd0a2a5a3a935 165 Gene3D G3DSA:3.40.30.10 80 165 1.4E-25 T 13-10-2018 Spica_2777 f3768e0415b88e48b44fd0a2a5a3a935 165 SUPERFAMILY SSF52833 15 162 9.73E-46 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_2777 f3768e0415b88e48b44fd0a2a5a3a935 165 Gene3D G3DSA:1.10.10.1590 11 79 1.6E-12 T 13-10-2018 Spica_2777 f3768e0415b88e48b44fd0a2a5a3a935 165 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 20 162 1.1E-44 T 13-10-2018 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 SUPERFAMILY SSF46689 325 363 7.17E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 Gene3D G3DSA:1.10.10.60 255 361 4.8E-19 T 13-10-2018 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 343 359 6.8E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 328 343 6.8E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 SMART SM00342 273 359 7.0E-10 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_2465 e8ab1deb41420aa02dd0cdf875c7b051 372 Pfam PF12833 Helix-turn-helix domain 279 361 2.6E-15 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Spica_0241 3fdcd5f7dec6db93d10dcbcb6d049345 383 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 261 5.6E-16 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spica_0241 3fdcd5f7dec6db93d10dcbcb6d049345 383 Gene3D G3DSA:3.40.50.300 2 299 3.3E-38 T 13-10-2018 Spica_0241 3fdcd5f7dec6db93d10dcbcb6d049345 383 SUPERFAMILY SSF52540 1 298 2.78E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1726 f5e05f7be7ea43546aa2dbb4084b56ac 331 Pfam PF03116 NQR2, RnfD, RnfE family 6 298 1.4E-76 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 Spica_0596 0f215acf56c980fd617fc1433b56a0f4 210 Pfam PF01522 Polysaccharide deacetylase 6 115 8.4E-26 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Spica_0596 0f215acf56c980fd617fc1433b56a0f4 210 Gene3D G3DSA:3.20.20.370 4 207 8.8E-57 T 13-10-2018 Spica_0596 0f215acf56c980fd617fc1433b56a0f4 210 SUPERFAMILY SSF88713 6 192 2.72E-46 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_0059 2430a2298c5e306e229f6a7f283efbe4 446 Gene3D G3DSA:3.40.190.10 156 430 2.4E-72 T 13-10-2018 Spica_0059 2430a2298c5e306e229f6a7f283efbe4 446 Pfam PF13416 Bacterial extracellular solute-binding protein 62 378 9.6E-29 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0059 2430a2298c5e306e229f6a7f283efbe4 446 SUPERFAMILY SSF53850 33 442 2.61E-55 T 13-10-2018 Spica_0059 2430a2298c5e306e229f6a7f283efbe4 446 Gene3D G3DSA:3.40.190.10 58 400 2.4E-72 T 13-10-2018 Spica_0264 ecce094780436597491c271c9e880268 199 Gene3D G3DSA:3.90.70.10 28 172 3.9E-21 T 13-10-2018 Spica_0264 ecce094780436597491c271c9e880268 199 Pfam PF03412 Peptidase C39 family 25 164 4.6E-17 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 Spica_1556 94fc8251bde9498e05ef5a6769950447 319 Pfam PF08308 PEGA domain 109 171 9.7E-16 T 13-10-2018 IPR013229 PEGA Spica_1556 94fc8251bde9498e05ef5a6769950447 319 Pfam PF08308 PEGA domain 175 237 6.7E-10 T 13-10-2018 IPR013229 PEGA Spica_2411 b9b83f743827761284fe72f2bc131f8e 169 Gene3D G3DSA:3.30.450.20 14 169 1.3E-21 T 13-10-2018 Spica_2411 b9b83f743827761284fe72f2bc131f8e 169 Pfam PF08269 Cache domain 54 167 2.2E-14 T 13-10-2018 IPR004010 Double Cache domain 2 Spica_2411 b9b83f743827761284fe72f2bc131f8e 169 SMART SM01049 26 112 8.3E-9 T 13-10-2018 IPR033480 Single Cache domain 2 Spica_0753 389b3f31ff7a550f34169a1a806d64ef 242 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 49 242 38.169 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0753 389b3f31ff7a550f34169a1a806d64ef 242 Pfam PF00925 GTP cyclohydrolase II 55 218 2.1E-63 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0753 389b3f31ff7a550f34169a1a806d64ef 242 Gene3D G3DSA:3.40.50.10990 50 222 2.8E-71 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0753 389b3f31ff7a550f34169a1a806d64ef 242 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 53 242 2.2E-71 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0753 389b3f31ff7a550f34169a1a806d64ef 242 SUPERFAMILY SSF142695 51 221 9.81E-62 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Spica_0414 3849442bd19be8cdad42ae648017d3be 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 284 5.1E-51 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 Gene3D G3DSA:1.10.3080.10 25 446 9.7E-101 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 SUPERFAMILY SSF81340 15 442 8.24E-102 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 Pfam PF00654 Voltage gated chloride channel 86 426 2.7E-88 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 PRINTS PR00762 Chloride channel signature 394 413 2.7E-25 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 PRINTS PR00762 Chloride channel signature 98 115 2.7E-25 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 PRINTS PR00762 Chloride channel signature 341 361 2.7E-25 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 PRINTS PR00762 Chloride channel signature 376 392 2.7E-25 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_0579 6f3868d1ee167e68e2152d9c214b896d 456 PRINTS PR00762 Chloride channel signature 178 197 2.7E-25 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 Spica_1250 f6ca0142a135ea75f901d408f2dd726a 435 Pfam PF13482 RNase_H superfamily 106 278 6.4E-25 T 13-10-2018 IPR038720 YprB, ribonuclease H-like domain Spica_1250 f6ca0142a135ea75f901d408f2dd726a 435 SUPERFAMILY SSF53098 105 281 6.4E-27 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_1250 f6ca0142a135ea75f901d408f2dd726a 435 Gene3D G3DSA:3.30.420.10 105 231 7.8E-8 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_1465 a4666b039d1602d9dab1a628a7161504 400 SUPERFAMILY SSF53756 36 389 2.09E-56 T 13-10-2018 Spica_1465 a4666b039d1602d9dab1a628a7161504 400 Pfam PF13439 Glycosyltransferase Family 4 62 182 6.5E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Spica_1465 a4666b039d1602d9dab1a628a7161504 400 Pfam PF00534 Glycosyl transferases group 1 201 366 2.5E-29 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Spica_1465 a4666b039d1602d9dab1a628a7161504 400 Gene3D G3DSA:3.40.50.2000 180 374 2.6E-49 T 13-10-2018 Spica_1465 a4666b039d1602d9dab1a628a7161504 400 Gene3D G3DSA:3.40.50.2000 52 387 2.6E-49 T 13-10-2018 Spica_0035 3abdb7b87186e91182b5bb953b49fe25 371 SUPERFAMILY SSF53822 35 357 3.43E-56 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Spica_0035 3abdb7b87186e91182b5bb953b49fe25 371 Pfam PF13407 Periplasmic binding protein domain 36 319 7.7E-59 T 13-10-2018 IPR025997 Periplasmic binding protein Spica_0035 3abdb7b87186e91182b5bb953b49fe25 371 Gene3D G3DSA:3.40.50.2300 36 345 1.6E-115 T 13-10-2018 Spica_0035 3abdb7b87186e91182b5bb953b49fe25 371 Gene3D G3DSA:3.40.50.2300 137 366 1.6E-115 T 13-10-2018 Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 Gene3D G3DSA:3.40.50.300 211 423 2.7E-69 T 13-10-2018 Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 Pfam PF13638 PIN domain 8 143 2.5E-27 T 13-10-2018 IPR002716 PIN domain Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 Pfam PF02562 PhoH-like protein 213 420 2.5E-53 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 SMART SM00670 6 130 1.8E-15 T 13-10-2018 IPR002716 PIN domain Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 SUPERFAMILY SSF52540 158 399 2.77E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 Gene3D G3DSA:3.40.50.1010 2 146 1.9E-21 T 13-10-2018 Spica_1222 c42c2e6de0c7b56ea4f4032ebacd307b 424 SUPERFAMILY SSF88723 7 144 6.54E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_2272 ed5e08e493c682b9472921452a88131a 84 Gene3D G3DSA:3.40.1620.10 2 39 4.5E-6 T 13-10-2018 Spica_2345 9d77a38b99c615e42e8131818a46b92d 453 SUPERFAMILY SSF58104 185 373 4.05E-12 T 13-10-2018 Spica_2345 9d77a38b99c615e42e8131818a46b92d 453 Gene3D G3DSA:1.10.287.950 147 383 1.7E-11 T 13-10-2018 Spica_0575 1abb6c33fa35b5cabf1d4d340eb84fc9 299 SUPERFAMILY SSF52777 9 274 3.81E-15 T 13-10-2018 Spica_0575 1abb6c33fa35b5cabf1d4d340eb84fc9 299 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 15 102 5.9E-7 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Spica_0575 1abb6c33fa35b5cabf1d4d340eb84fc9 299 Gene3D G3DSA:3.30.559.10 8 150 3.5E-8 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Spica_0575 1abb6c33fa35b5cabf1d4d340eb84fc9 299 Gene3D G3DSA:3.30.559.10 192 277 2.4E-5 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Spica_1719 522c2886e31d533e08da14af7d423887 307 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 181 206 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 Spica_1719 522c2886e31d533e08da14af7d423887 307 Gene3D G3DSA:1.10.600.10 10 300 9.9E-49 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_1719 522c2886e31d533e08da14af7d423887 307 Pfam PF00494 Squalene/phytoene synthase 25 291 3.2E-41 T 13-10-2018 Spica_1719 522c2886e31d533e08da14af7d423887 307 SUPERFAMILY SSF48576 19 303 5.32E-52 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Spica_0654 809d38f588c1b6e183941b1e95eb204f 238 Pfam PF03591 AzlC protein 20 159 4.7E-40 T 13-10-2018 IPR011606 Branched-chain amino acid transport, permease Spica_0901 cdf71521fbc3631c5b630791e91bf556 423 Pfam PF03773 Predicted permease 20 414 6.9E-45 T 13-10-2018 IPR005524 Predicted permease DUF318 Spica_1565 0f5ab4351c44476bdd3c40c6a72101e6 280 Pfam PF02517 CAAX protease self-immunity 132 237 4.0E-13 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Spica_1792 3927954ce6fd74267e3cffadcd1fe5d8 81 SUPERFAMILY SSF47598 4 58 1.89E-6 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1792 3927954ce6fd74267e3cffadcd1fe5d8 81 Pfam PF07878 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 10 41 2.0E-7 T 13-10-2018 IPR012869 CopG-like ribbon-helix-helix domain Spica_2708 bf8101bf955b46c3b116e011481249bd 349 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 53 349 8.2E-97 T 13-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 Gene3D G3DSA:3.30.460.20 2 158 2.2E-44 T 13-10-2018 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 SUPERFAMILY SSF144083 284 346 4.32E-23 T 13-10-2018 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 Pfam PF01544 CorA-like Mg2+ transporter protein 56 345 1.6E-79 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 SUPERFAMILY SSF143865 8 283 1.11E-78 T 13-10-2018 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 Gene3D G3DSA:1.20.58.340 272 349 2.3E-35 T 13-10-2018 Spica_2708 bf8101bf955b46c3b116e011481249bd 349 Gene3D G3DSA:1.20.58.340 159 270 1.1E-37 T 13-10-2018 Spica_1211 6f472e2b353acb732fb30461cf3b4f37 253 Pfam PF06738 Putative threonine/serine exporter 14 251 5.2E-64 T 13-10-2018 IPR010619 Putative threonine/serine exporter Spica_0350 dcd3cdb939c26351912012d942590a38 75 SUPERFAMILY SSF89447 1 48 5.93E-9 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Spica_0350 dcd3cdb939c26351912012d942590a38 75 Gene3D G3DSA:2.10.260.10 1 75 5.8E-6 T 13-10-2018 Spica_2822 cb4d1308e8c6b223e2a383a04f26eb94 268 Gene3D G3DSA:3.40.50.1820 18 268 1.2E-69 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2822 cb4d1308e8c6b223e2a383a04f26eb94 268 Pfam PF00756 Putative esterase 45 259 1.6E-31 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Spica_2822 cb4d1308e8c6b223e2a383a04f26eb94 268 SUPERFAMILY SSF53474 28 267 2.3E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2207 f0ab7a77f908ee8886b02406f3b109f8 329 Pfam PF04463 Protein of unknown function (DUF523) 12 153 9.9E-27 T 13-10-2018 IPR007553 Domain of unknown function DUF523 Spica_2207 f0ab7a77f908ee8886b02406f3b109f8 329 Pfam PF08349 Protein of unknown function (DUF1722) 195 311 2.6E-38 T 13-10-2018 IPR013560 Domain of unknown function DUF1722 Spica_0425 7c1f04e6d1a5a2aee5f0146537016c23 91 Gene3D G3DSA:3.30.2310.20 1 90 2.5E-12 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_0425 7c1f04e6d1a5a2aee5f0146537016c23 91 SUPERFAMILY SSF143011 4 86 9.81E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_1500 5bc88ea2d8580ddaa144ab725a92878c 619 Pfam PF01496 V-type ATPase 116kDa subunit family 267 471 1.1E-8 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_2460 054d95b9e4d5ce8e3be33a77d7723ed8 403 Pfam PF01610 Transposase 156 391 1.1E-71 T 13-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain Spica_2460 054d95b9e4d5ce8e3be33a77d7723ed8 403 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 6.7E-17 T 13-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain Spica_2786 431e45ee4c896b060f9eaab8cce9f5f0 172 Gene3D G3DSA:2.160.10.10 1 171 6.2E-60 T 13-10-2018 Spica_2786 431e45ee4c896b060f9eaab8cce9f5f0 172 SUPERFAMILY SSF51161 3 168 4.71E-47 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_2786 431e45ee4c896b060f9eaab8cce9f5f0 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 8.3E-10 T 13-10-2018 IPR001451 Hexapeptide repeat Spica_0270 70700ccdf145d591603abcb505b83fd6 229 PRINTS PR01837 MgtC/SapB protein signature 96 120 8.7E-43 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Spica_0270 70700ccdf145d591603abcb505b83fd6 229 PRINTS PR01837 MgtC/SapB protein signature 18 37 8.7E-43 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Spica_0270 70700ccdf145d591603abcb505b83fd6 229 PRINTS PR01837 MgtC/SapB protein signature 37 55 8.7E-43 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Spica_0270 70700ccdf145d591603abcb505b83fd6 229 PRINTS PR01837 MgtC/SapB protein signature 69 91 8.7E-43 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Spica_0270 70700ccdf145d591603abcb505b83fd6 229 Pfam PF02308 MgtC family 15 142 3.9E-36 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 Gene3D G3DSA:1.20.1480.50 192 290 2.2E-12 T 13-10-2018 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 SMART SM00304 230 284 1.2E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 SMART SM01049 43 137 2.9E-20 T 13-10-2018 IPR033480 Single Cache domain 2 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 SUPERFAMILY SSF58104 252 573 1.7E-51 T 13-10-2018 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 Gene3D G3DSA:1.10.287.950 303 574 4.9E-51 T 13-10-2018 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 393 542 2.6E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 SMART SM00283 327 574 2.0E-50 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 Gene3D G3DSA:3.30.450.20 42 191 8.4E-34 T 13-10-2018 Spica_0048 8b0f9f50ada0a1cc31987d542f5fb995 620 Pfam PF17200 Single Cache domain 2 47 194 2.5E-32 T 13-10-2018 IPR033480 Single Cache domain 2 Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 SUPERFAMILY SSF58104 119 189 2.88E-14 T 13-10-2018 Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 Gene3D G3DSA:1.10.287.950 100 196 1.0E-13 T 13-10-2018 Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 Pfam PF05651 Putative sugar diacid recognition 8 129 8.0E-28 T 13-10-2018 IPR008599 Putative sugar diacid recognition Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 166 195 3.1E-6 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 137 164 3.1E-6 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Spica_2711 f986f65bc9064e5d938f661e526ad62e 196 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 128 188 3.1E-10 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0656 0dc1da79066a07ef201b031312cb203a 632 SUPERFAMILY SSF58104 267 590 2.35E-38 T 13-10-2018 Spica_0656 0dc1da79066a07ef201b031312cb203a 632 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 407 538 5.3E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_0656 0dc1da79066a07ef201b031312cb203a 632 Gene3D G3DSA:1.10.287.950 327 591 1.4E-38 T 13-10-2018 Spica_0656 0dc1da79066a07ef201b031312cb203a 632 SMART SM00283 356 589 2.1E-15 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Spica_1202 5913f35779b40f659d0b175c0c096f70 321 Gene3D G3DSA:2.170.120.30 40 132 1.4E-14 T 13-10-2018 Spica_1202 5913f35779b40f659d0b175c0c096f70 321 Pfam PF07949 YbbR-like protein 139 210 9.4E-11 T 13-10-2018 IPR012505 YbbR-like Spica_1202 5913f35779b40f659d0b175c0c096f70 321 Gene3D G3DSA:2.170.120.40 135 220 1.6E-10 T 13-10-2018 Spica_1202 5913f35779b40f659d0b175c0c096f70 321 Gene3D G3DSA:2.170.120.30 227 317 1.1E-10 T 13-10-2018 Spica_0666 08626a6a1f83182e07a4b02883d87a26 186 Gene3D G3DSA:1.10.10.1320 1 104 5.9E-7 T 13-10-2018 Spica_0666 08626a6a1f83182e07a4b02883d87a26 186 Pfam PF13490 Putative zinc-finger 5 34 6.2E-8 T 13-10-2018 IPR027383 Putative zinc-finger Spica_0282 ff36e4fcb4d4398d6bf769a9b9700172 152 SUPERFAMILY SSF49785 19 120 3.4E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Spica_0282 ff36e4fcb4d4398d6bf769a9b9700172 152 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 31 97 1.3E-8 T 13-10-2018 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Reactome: R-HSA-6799198 Spica_0483 f48aac36b2795cb18dfb6609455b708f 84 Gene3D G3DSA:3.40.1690.10 3 83 1.4E-19 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Spica_0483 f48aac36b2795cb18dfb6609455b708f 84 SUPERFAMILY SSF160544 5 80 9.29E-17 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Spica_0483 f48aac36b2795cb18dfb6609455b708f 84 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 77 3.4E-15 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Spica_2757 89b9cd15271cda5b2d1da96f67abab52 301 Pfam PF10646 Sporulation and spore germination 168 282 4.3E-20 T 13-10-2018 IPR019606 GerMN domain Spica_2757 89b9cd15271cda5b2d1da96f67abab52 301 SMART SM00909 195 286 1.2E-21 T 13-10-2018 IPR019606 GerMN domain Spica_0121 b4205e27ece0b553a5259c88e0047f0f 252 SUPERFAMILY SSF51182 81 201 9.33E-7 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_0121 b4205e27ece0b553a5259c88e0047f0f 252 Gene3D G3DSA:2.60.120.10 25 248 1.0E-83 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0121 b4205e27ece0b553a5259c88e0047f0f 252 Pfam PF07385 D-lyxose isomerase 24 245 1.0E-98 T 13-10-2018 IPR010864 D-lyxose isomerase KEGG: 00040+5.3.1.15 Spica_0098 15f87e94207157e296ab5cfa31697a4f 133 SUPERFAMILY SSF46689 1 90 1.02E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Spica_0098 15f87e94207157e296ab5cfa31697a4f 133 Pfam PF01527 Transposase 2 66 1.7E-8 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Spica_2339 79cb28a72ef41ddea9080365d56c45a2 172 SUPERFAMILY SSF64438 13 163 5.95E-40 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spica_2339 79cb28a72ef41ddea9080365d56c45a2 172 Gene3D G3DSA:3.30.1330.200 12 167 9.5E-44 T 13-10-2018 IPR038592 CheD-like superfamily Spica_2339 79cb28a72ef41ddea9080365d56c45a2 172 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 8 162 24.51 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Spica_2339 79cb28a72ef41ddea9080365d56c45a2 172 Pfam PF03975 CheD chemotactic sensory transduction 62 157 5.7E-23 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 Spica_1660 e8a2060d08b242982f7087b442cafe08 465 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 94 337 1.5E-21 T 13-10-2018 IPR010839 Acyclic terpene utilisation Spica_0675 a8536dfcf4cd40f14ab1cd26fb10d077 296 Pfam PF07238 PilZ domain 146 260 2.9E-6 T 13-10-2018 IPR009875 PilZ domain GO:0035438 Spica_1149 c2c136cb9c971646d581c0be04905aa9 121 Pfam PF04519 Polymer-forming cytoskeletal 16 112 1.2E-24 T 13-10-2018 IPR007607 Bactofilin A/B Spica_0354 153cf1b49f7ddefeb4d14586c7435564 304 Gene3D G3DSA:1.10.3720.10 51 302 8.6E-59 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0354 153cf1b49f7ddefeb4d14586c7435564 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 298 1.6E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0354 153cf1b49f7ddefeb4d14586c7435564 304 SUPERFAMILY SSF161098 55 289 2.35E-49 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2616 000779eee83724c3592732c86585c2fe 389 Pfam PF01966 HD domain 249 317 6.0E-5 T 13-10-2018 IPR006674 HD domain Spica_2616 000779eee83724c3592732c86585c2fe 389 SUPERFAMILY SSF109604 201 322 6.28E-13 T 13-10-2018 Spica_2616 000779eee83724c3592732c86585c2fe 389 Gene3D G3DSA:1.10.3090.10 139 387 6.0E-13 T 13-10-2018 Spica_2113 857aeee019c79fa4a736a82e05029a3d 134 Gene3D G3DSA:3.30.420.270 59 129 3.5E-12 T 13-10-2018 Spica_2113 857aeee019c79fa4a736a82e05029a3d 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 132 4.1E-25 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Spica_0164 0f64d4eea9ae440a5bf9deb0bd826367 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 254 5.5E-80 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 Spica_0164 0f64d4eea9ae440a5bf9deb0bd826367 258 SUPERFAMILY SSF51556 1 255 5.11E-76 T 13-10-2018 IPR032466 Metal-dependent hydrolase Spica_0164 0f64d4eea9ae440a5bf9deb0bd826367 258 Pfam PF01026 TatD related DNase 4 253 2.1E-69 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_0164 0f64d4eea9ae440a5bf9deb0bd826367 258 Gene3D G3DSA:3.20.20.140 1 254 1.2E-78 T 13-10-2018 Spica_0164 0f64d4eea9ae440a5bf9deb0bd826367 258 PIRSF PIRSF005902 1 258 5.8E-70 T 13-10-2018 IPR001130 TatD family GO:0016788 Spica_2352 0f1ec6256ac1d7f55f24780d74104130 499 Pfam PF00488 MutS domain V 327 487 5.7E-22 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_2352 0f1ec6256ac1d7f55f24780d74104130 499 SUPERFAMILY SSF52540 282 454 3.06E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2352 0f1ec6256ac1d7f55f24780d74104130 499 SMART SM00534 323 499 9.1E-10 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Spica_2352 0f1ec6256ac1d7f55f24780d74104130 499 Gene3D G3DSA:3.40.50.300 282 494 3.7E-38 T 13-10-2018 Spica_2752 3b1f5d52cd75949bbd277d5d8c069dca 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 12 252 1.2E-70 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria Spica_2752 3b1f5d52cd75949bbd277d5d8c069dca 259 Pfam PF02405 Permease MlaE 41 249 1.2E-72 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 Spica_0432 a160e08d113983efbf7ea5940484ec14 160 SUPERFAMILY SSF53098 5 149 9.23E-52 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0432 a160e08d113983efbf7ea5940484ec14 160 Pfam PF00075 RNase H 4 149 2.9E-47 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 Spica_0432 a160e08d113983efbf7ea5940484ec14 160 Hamap MF_00042 Ribonuclease H [rnhA]. 3 158 32.93 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 Spica_0432 a160e08d113983efbf7ea5940484ec14 160 Gene3D G3DSA:3.30.420.10 1 156 6.8E-55 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_1083 b70cd412a21693696772b0d2de51a322 403 Pfam PF00872 Transposase, Mutator family 18 380 2.9E-120 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Spica_1083 b70cd412a21693696772b0d2de51a322 403 ProSitePatterns PS01007 Transposases, Mutator family, signature. 235 259 - T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Spica_1588 faa341532067a58645b1db5d62d99e74 402 Gene3D G3DSA:1.25.10.10 76 401 9.8E-8 T 13-10-2018 IPR011989 Armadillo-like helical Spica_1588 faa341532067a58645b1db5d62d99e74 402 SUPERFAMILY SSF48371 84 377 7.12E-11 T 13-10-2018 IPR016024 Armadillo-type fold Spica_0568 3d59e260de30c22463199e7ad4ad4ba1 76 SUPERFAMILY SSF47598 1 41 1.81E-6 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1520 33069dd09d30ecb712b741ed256e2e4f 653 Pfam PF14804 Jag N-terminus 27 74 4.9E-15 T 13-10-2018 IPR032782 Jag, N-terminal Spica_1520 33069dd09d30ecb712b741ed256e2e4f 653 SMART SM01245 25 76 2.5E-15 T 13-10-2018 IPR032782 Jag, N-terminal Spica_1520 33069dd09d30ecb712b741ed256e2e4f 653 Gene3D G3DSA:3.30.30.80 20 76 5.2E-15 T 13-10-2018 IPR038247 Jag, N-terminal domain superfamily Spica_1520 33069dd09d30ecb712b741ed256e2e4f 653 Pfam PF03961 Flagellar Assembly Protein A 179 630 8.7E-137 T 13-10-2018 IPR005646 Flagellar assembly protein A Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 7 165 24.027 T 13-10-2018 IPR022973 Ribosomal protein L10 Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 171 2.0E-5 T 13-10-2018 Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 Gene3D G3DSA:3.30.70.1730 4 177 3.9E-36 T 13-10-2018 Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 SUPERFAMILY SSF160369 10 176 4.97E-50 T 13-10-2018 Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 ProSitePatterns PS01109 Ribosomal protein L10 signature. 12 46 - T 13-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Spica_0377 c2ae79877f6d2c73a9670194cc832376 181 Pfam PF00466 Ribosomal protein L10 9 105 1.2E-23 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Spica_0609 c9a7f4b167382b16151a354c33bae251 418 SUPERFAMILY SSF51735 99 175 2.49E-5 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Spica_0609 c9a7f4b167382b16151a354c33bae251 418 Gene3D G3DSA:3.40.50.720 66 176 3.2E-10 T 13-10-2018 Spica_0609 c9a7f4b167382b16151a354c33bae251 418 Gene3D G3DSA:3.40.50.261 194 329 6.6E-42 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_0609 c9a7f4b167382b16151a354c33bae251 418 SUPERFAMILY SSF52210 187 320 1.57E-13 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Spica_2283 c63ac161e6139f88c2461e7fe3926ad4 428 Gene3D G3DSA:3.30.565.10 299 417 3.3E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2283 c63ac161e6139f88c2461e7fe3926ad4 428 SUPERFAMILY SSF55874 299 408 7.99E-14 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2283 c63ac161e6139f88c2461e7fe3926ad4 428 Pfam PF07730 Histidine kinase 224 287 4.9E-11 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Spica_2137 e9634b0aa9188ed8ba19ea7e6b8deb78 424 Gene3D G3DSA:3.40.50.12580 223 393 6.8E-11 T 13-10-2018 Spica_2137 e9634b0aa9188ed8ba19ea7e6b8deb78 424 SUPERFAMILY SSF53756 82 342 3.35E-8 T 13-10-2018 Spica_2137 e9634b0aa9188ed8ba19ea7e6b8deb78 424 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 226 349 1.3E-10 T 13-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 Spica_1433 32bda487ba5108fae5a888b8f007bbc7 111 SUPERFAMILY SSF48452 28 86 5.38E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0797 5d01ff23ac25f5d95a90c24fe6056472 118 SUPERFAMILY SSF52091 14 96 2.35E-10 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0797 5d01ff23ac25f5d95a90c24fe6056472 118 Pfam PF13466 STAS domain 19 94 2.2E-11 T 13-10-2018 IPR002645 STAS domain Spica_0797 5d01ff23ac25f5d95a90c24fe6056472 118 Gene3D G3DSA:3.30.750.24 3 95 2.3E-9 T 13-10-2018 IPR036513 STAS domain superfamily Spica_2594 2c6f69089d4eb64b0aea12b56bc91145 333 SUPERFAMILY SSF64182 24 308 1.83E-42 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Spica_2594 2c6f69089d4eb64b0aea12b56bc91145 333 Pfam PF02272 DHHA1 domain 224 313 2.9E-11 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Spica_2594 2c6f69089d4eb64b0aea12b56bc91145 333 Pfam PF01368 DHH family 26 169 3.1E-9 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Spica_2594 2c6f69089d4eb64b0aea12b56bc91145 333 Gene3D G3DSA:3.90.1640.10 25 207 4.1E-27 T 13-10-2018 Spica_0426 9a191a653f33ae50456b8f602789d1a2 180 SUPERFAMILY SSF52141 5 176 1.31E-23 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_0426 9a191a653f33ae50456b8f602789d1a2 180 Gene3D G3DSA:3.40.470.10 1 179 5.1E-41 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Spica_0426 9a191a653f33ae50456b8f602789d1a2 180 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 5 123 3.9E-34 T 13-10-2018 IPR026353 Hypoxanthine-DNA glycosylase Spica_0280 ba33dabb775478721ffa61b342f30a8b 131 Gene3D G3DSA:3.40.50.1010 1 131 1.3E-40 T 13-10-2018 Spica_0280 ba33dabb775478721ffa61b342f30a8b 131 SUPERFAMILY SSF88723 1 130 3.36E-37 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_0280 ba33dabb775478721ffa61b342f30a8b 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 129 10.336 T 13-10-2018 IPR022907 VapC family GO:0004540 Spica_0280 ba33dabb775478721ffa61b342f30a8b 131 Pfam PF01850 PIN domain 2 123 3.4E-15 T 13-10-2018 IPR002716 PIN domain Spica_1348 f421c19306f6cdbd1dc8be374354d2ac 177 SMART SM00935 12 172 1.2E-15 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Spica_1348 f421c19306f6cdbd1dc8be374354d2ac 177 SUPERFAMILY SSF111384 25 171 3.66E-17 T 13-10-2018 Spica_1348 f421c19306f6cdbd1dc8be374354d2ac 177 Gene3D G3DSA:3.30.910.20 16 176 3.1E-20 T 13-10-2018 IPR024930 Skp domain superfamily Spica_1348 f421c19306f6cdbd1dc8be374354d2ac 177 Pfam PF03938 Outer membrane protein (OmpH-like) 12 171 3.2E-23 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Spica_1812 cce8fe9c875bbfa99ed6739f886092f0 135 Gene3D G3DSA:3.40.50.360 3 134 5.6E-6 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_1812 cce8fe9c875bbfa99ed6739f886092f0 135 SUPERFAMILY SSF52218 1 116 2.77E-6 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_0076 74ca51036bd70033859f55c788c51dbc 271 Gene3D G3DSA:2.50.20.10 35 269 6.6E-61 T 13-10-2018 Spica_0076 74ca51036bd70033859f55c788c51dbc 271 Pfam PF17131 Outer membrane lipoprotein-sorting protein 77 269 2.8E-47 T 13-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein Spica_0039 e37b8e9aefcfbfcfdcc37aae4d57d6ed 67 Pfam PF11127 Protein of unknown function (DUF2892) 1 66 8.0E-18 T 13-10-2018 IPR021309 Protein of unknown function DUF2892 Spica_1240 820c3b7907af5b31a0f8bb9c2309cec0 422 Pfam PF02687 FtsX-like permease family 298 415 1.7E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Spica_1240 820c3b7907af5b31a0f8bb9c2309cec0 422 Pfam PF12704 MacB-like periplasmic core domain 28 227 1.5E-6 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Spica_0865 d7870307b1115ce33926850a3aad6072 172 Pfam PF01899 Na+/H+ ion antiporter subunit 19 170 6.2E-32 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Spica_0865 d7870307b1115ce33926850a3aad6072 172 PIRSF PIRSF019239 9 171 1.3E-36 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 Spica_2703 baddda87c776c0865ce9b9a76f5a55ed 73 SUPERFAMILY SSF54786 4 72 1.02E-19 T 13-10-2018 Spica_2703 baddda87c776c0865ce9b9a76f5a55ed 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 9 64 6.1E-19 T 13-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 Spica_2703 baddda87c776c0865ce9b9a76f5a55ed 73 Gene3D G3DSA:3.30.920.30 5 72 2.7E-18 T 13-10-2018 IPR038570 HicA superfamily Spica_1219 acd60dc7c89241ecb3bae2171d9eb48d 134 Gene3D G3DSA:2.10.109.10 23 134 7.9E-24 T 13-10-2018 Spica_1219 acd60dc7c89241ecb3bae2171d9eb48d 134 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 96 3.9E-14 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Spica_1219 acd60dc7c89241ecb3bae2171d9eb48d 134 Pfam PF00717 Peptidase S24-like 35 102 1.2E-10 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Spica_1219 acd60dc7c89241ecb3bae2171d9eb48d 134 SUPERFAMILY SSF51306 27 132 1.74E-26 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Spica_1288 09b065f46d70073ef09b8a40e195780e 538 Pfam PF09822 ABC-type uncharacterized transport system 30 287 4.1E-57 T 13-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 Spica_2292 bd75b578a865c15d8145e68a17361839 93 Gene3D G3DSA:3.30.2310.20 8 92 3.2E-8 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_2292 bd75b578a865c15d8145e68a17361839 93 SUPERFAMILY SSF143011 1 90 1.11E-11 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_0807 7e275508a5adab11fcb7fa8bd1691358 586 Pfam PF01973 Protein of unknown function DUF115 172 348 4.5E-23 T 13-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Spica_2295 33912ce86370249e97414e7002423a05 300 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 38 295 7.5E-37 T 13-10-2018 IPR023875 DNA metabolism protein, putative Spica_2295 33912ce86370249e97414e7002423a05 300 Pfam PF13566 Domain of unknown function (DUF4130 162 295 1.0E-26 T 13-10-2018 IPR025404 Domain of unknown function DUF4130 Spica_0195 055775b0e174de20a7317d390b76c946 354 SUPERFAMILY SSF143631 43 341 3.14E-96 T 13-10-2018 IPR003374 ApbE-like superfamily Spica_0195 055775b0e174de20a7317d390b76c946 354 Gene3D G3DSA:3.10.520.20 37 353 2.4E-112 T 13-10-2018 Spica_0195 055775b0e174de20a7317d390b76c946 354 PIRSF PIRSF006268 13 348 1.1E-106 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Spica_0195 055775b0e174de20a7317d390b76c946 354 Pfam PF02424 ApbE family 49 325 3.4E-86 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Spica_1551 6791513152e6657833ee62f82873dd69 68 Gene3D G3DSA:3.30.160.250 1 56 9.3E-9 T 13-10-2018 Spica_1551 6791513152e6657833ee62f82873dd69 68 SUPERFAMILY SSF143100 3 48 1.83E-11 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like Spica_1857 0c46e3d619ac0d65b42f7b37bd7b8e73 104 SUPERFAMILY SSF47413 26 92 7.64E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Spica_1857 0c46e3d619ac0d65b42f7b37bd7b8e73 104 Gene3D G3DSA:1.10.260.40 17 89 1.1E-6 T 13-10-2018 Spica_1542 6e377b1e66c03ae46cbb07edb9d8425c 316 Gene3D G3DSA:3.40.1790.10 6 311 9.5E-138 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spica_1542 6e377b1e66c03ae46cbb07edb9d8425c 316 SUPERFAMILY SSF110581 9 307 3.14E-117 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spica_1542 6e377b1e66c03ae46cbb07edb9d8425c 316 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 15 309 44.978 T 13-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spica_1542 6e377b1e66c03ae46cbb07edb9d8425c 316 Pfam PF04227 Indigoidine synthase A like protein 16 305 6.1E-134 T 13-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 Spica_1172 6e4ae573fa1cda101cf78f4099ed9468 304 SUPERFAMILY SSF110849 91 145 7.32E-7 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 181 313 2.0E-26 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 PRINTS PR00133 Glycosyl hydrolase family 3 signature 146 162 7.0E-6 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 PRINTS PR00133 Glycosyl hydrolase family 3 signature 170 189 7.0E-6 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 Gene3D G3DSA:3.20.20.300 191 327 4.1E-33 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 Gene3D G3DSA:3.20.20.300 62 190 2.2E-39 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Spica_0765 ef6f4a6dbc0c4de454fce71feb435c79 345 SUPERFAMILY SSF51445 65 310 7.69E-59 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Spica_2742 ba4dfd41a8007a4c79f051a39f873781 267 Gene3D G3DSA:2.160.20.120 52 266 1.9E-50 T 13-10-2018 Spica_2742 ba4dfd41a8007a4c79f051a39f873781 267 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 70 252 2.7E-42 T 13-10-2018 IPR021255 Putative auto-transporter adhesin, head GIN domain Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 Pfam PF03600 Citrate transporter 252 420 4.8E-10 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 Pfam PF03600 Citrate transporter 39 209 1.4E-22 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 PRINTS PR00758 Arsenical pump membrane protein signature 115 139 1.2E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 1.2E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 PRINTS PR00758 Arsenical pump membrane protein signature 188 211 1.2E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_1253 ba2a56eb8440f00e014b29a2b2a421b8 422 PRINTS PR00758 Arsenical pump membrane protein signature 396 420 1.2E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_0044 8eea6a3d8d921e7e858541a2af133e0b 250 Gene3D G3DSA:2.20.25.110 146 202 1.5E-41 T 13-10-2018 Spica_0044 8eea6a3d8d921e7e858541a2af133e0b 250 Pfam PF13649 Methyltransferase domain 40 137 1.0E-16 T 13-10-2018 Spica_0044 8eea6a3d8d921e7e858541a2af133e0b 250 SUPERFAMILY SSF53335 3 244 4.15E-35 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0044 8eea6a3d8d921e7e858541a2af133e0b 250 Gene3D G3DSA:3.40.50.150 10 228 1.5E-41 T 13-10-2018 Spica_2212 18e1df2724b5493a95afb2d5084b651b 414 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 276 405 1.1E-16 T 13-10-2018 IPR024465 Domain of unknown function DUF2399 Spica_2212 18e1df2724b5493a95afb2d5084b651b 414 SUPERFAMILY SSF56726 275 405 2.48E-8 T 13-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 Spica_1049 51abfd599e8d30a7ac764575ce5b1a51 219 Pfam PF16258 Domain of unknown function (DUF4912) 72 175 1.8E-16 T 13-10-2018 IPR032585 Protein of unknown function DUF4912 Spica_2134 711064c57638159a31bf343db0e004d6 270 Pfam PF06182 ABC-2 family transporter protein 34 269 6.4E-26 T 13-10-2018 IPR010390 Protein of unknown function DUF990 Spica_0612 83e6d793b230fbc2ae0718d8a5853178 127 SUPERFAMILY SSF50249 11 115 6.85E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Spica_0927 187a22c7e74b72de36069e3567b97ade 235 SUPERFAMILY SSF103642 198 219 2.13E-5 T 13-10-2018 Spica_0927 187a22c7e74b72de36069e3567b97ade 235 Pfam PF02810 SEC-C motif 202 218 5.9E-6 T 13-10-2018 IPR004027 SEC-C motif Spica_1661 812c646897ab9597a5307c2da13d44c1 106 Pfam PF14330 Domain of unknown function (DUF4387) 5 102 1.1E-39 T 13-10-2018 IPR025496 Protein of unknown function DUF4387 Spica_0509 3ef64074bba4b4e9de3f886a6558fb44 190 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 157 8.8E-5 T 13-10-2018 IPR001451 Hexapeptide repeat Spica_0509 3ef64074bba4b4e9de3f886a6558fb44 190 SUPERFAMILY SSF51161 1 180 7.49E-31 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Spica_0509 3ef64074bba4b4e9de3f886a6558fb44 190 Gene3D G3DSA:2.160.10.10 93 190 2.1E-18 T 13-10-2018 Spica_0509 3ef64074bba4b4e9de3f886a6558fb44 190 Gene3D G3DSA:3.40.50.20 1 91 8.1E-21 T 13-10-2018 Spica_2861 fbe9a77b25a98d8ff03f7adda9774997 176 Pfam PF13527 Acetyltransferase (GNAT) domain 2 129 1.4E-13 T 13-10-2018 Spica_2861 fbe9a77b25a98d8ff03f7adda9774997 176 SUPERFAMILY SSF55729 1 135 2.66E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_2861 fbe9a77b25a98d8ff03f7adda9774997 176 Gene3D G3DSA:3.40.630.30 1 169 6.6E-36 T 13-10-2018 Spica_1568 000eddb5b7452700bcc8117ab83873e1 81 SUPERFAMILY SSF47598 3 56 9.45E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Spica_1785 dd4f7520773338df7459b569fa63a2b9 139 SUPERFAMILY SSF88723 1 130 7.57E-23 T 13-10-2018 IPR029060 PIN-like domain superfamily Spica_1785 dd4f7520773338df7459b569fa63a2b9 139 Pfam PF01850 PIN domain 5 122 6.2E-10 T 13-10-2018 IPR002716 PIN domain Spica_1785 dd4f7520773338df7459b569fa63a2b9 139 Gene3D G3DSA:3.40.50.1010 4 138 4.5E-29 T 13-10-2018 Spica_0322 0a67c9f900895ccecbb7d57542f5d3d5 273 Pfam PF01458 Uncharacterized protein family (UPF0051) 46 237 1.1E-50 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Spica_0322 0a67c9f900895ccecbb7d57542f5d3d5 273 SUPERFAMILY SSF101960 27 253 2.22E-57 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_1493 02a4d017c4e10dc577b8740f393afa63 727 Pfam PF04773 FecR protein 72 164 2.6E-11 T 13-10-2018 IPR006860 FecR protein Spica_1657 6de0cfd01142079ce5c77df6be8fec03 468 Pfam PF13941 MutL protein 6 460 5.0E-139 T 13-10-2018 IPR006230 Protein MutL Spica_1657 6de0cfd01142079ce5c77df6be8fec03 468 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 8 459 7.7E-113 T 13-10-2018 IPR006230 Protein MutL Spica_1657 6de0cfd01142079ce5c77df6be8fec03 468 PIRSF PIRSF004729 3 463 5.4E-121 T 13-10-2018 IPR006230 Protein MutL Spica_1967 0fe7cbe09c24ea3265e2ade63eda8f64 304 Pfam PF09992 Phosphodiester glycosidase 109 298 5.4E-31 T 13-10-2018 IPR018711 Phosphodiester glycosidase Spica_2596 9522bc07bb321ce51022c47b3310dff6 228 Gene3D G3DSA:3.30.530.20 73 185 4.7E-6 T 13-10-2018 IPR023393 START-like domain superfamily Spica_2531 6c6b2cd099848a3c053a2d46a81d26f8 3083 Gene3D G3DSA:2.60.40.4070 2998 3074 1.8E-10 T 13-10-2018 Spica_2775 2b8085a0dd58ecb4153b23fc328f68f7 132 SUPERFAMILY SSF52833 31 124 2.57E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_2775 2b8085a0dd58ecb4153b23fc328f68f7 132 Gene3D G3DSA:3.40.30.10 28 127 2.9E-18 T 13-10-2018 Spica_0548 09a80a84d8d05f126b5f0ff432e31b66 306 SUPERFAMILY SSF55729 126 296 6.2E-13 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Spica_0548 09a80a84d8d05f126b5f0ff432e31b66 306 Pfam PF03682 Uncharacterised protein family (UPF0158) 7 130 1.1E-11 T 13-10-2018 IPR005361 Uncharacterised protein family UPF0158 Spica_0548 09a80a84d8d05f126b5f0ff432e31b66 306 Gene3D G3DSA:3.40.630.30 83 303 9.0E-9 T 13-10-2018 Spica_2635 3f2ee418c1c84c547ea55dc3b892b442 177 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 7 177 1.2E-29 T 13-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 Spica_2635 3f2ee418c1c84c547ea55dc3b892b442 177 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 174 3.1E-37 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Spica_2635 3f2ee418c1c84c547ea55dc3b892b442 177 SUPERFAMILY SSF53323 6 177 4.18E-45 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_2635 3f2ee418c1c84c547ea55dc3b892b442 177 Gene3D G3DSA:3.40.920.10 3 177 1.5E-50 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Spica_1395 724509b506e5d6bf015a2a54a4974a4d 1166 Pfam PF13860 FlgD Ig-like domain 463 510 1.1E-7 T 13-10-2018 IPR025965 FlgD Ig-like domain Spica_1395 724509b506e5d6bf015a2a54a4974a4d 1166 Gene3D G3DSA:2.60.40.4070 444 520 3.7E-12 T 13-10-2018 Spica_1395 724509b506e5d6bf015a2a54a4974a4d 1166 Gene3D G3DSA:2.60.40.4070 864 940 5.2E-6 T 13-10-2018 Spica_0711 bfaf78e6b0dd8cbfa0d7d7cdfa9ef5df 85 Pfam PF07704 Rv0623-like transcription factor 2 78 9.0E-16 T 13-10-2018 IPR011660 Antitoxin VapB-like Spica_0272 c25d1a90ba04ca76868a24c59a63142a 382 Gene3D G3DSA:2.60.200.40 207 359 3.1E-14 T 13-10-2018 Spica_0272 c25d1a90ba04ca76868a24c59a63142a 382 Pfam PF00781 Diacylglycerol kinase catalytic domain 32 175 9.3E-9 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Spica_0272 c25d1a90ba04ca76868a24c59a63142a 382 SUPERFAMILY SSF111331 31 358 2.35E-31 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Spica_0272 c25d1a90ba04ca76868a24c59a63142a 382 Gene3D G3DSA:3.40.50.10330 26 192 2.4E-8 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Spica_1097 1c5ce88c4a5d61059353ede474788ec9 291 Gene3D G3DSA:3.40.50.150 1 279 1.0E-94 T 13-10-2018 Spica_1097 1c5ce88c4a5d61059353ede474788ec9 291 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 268 2.5E-64 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Spica_1097 1c5ce88c4a5d61059353ede474788ec9 291 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 264 38.425 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Spica_1097 1c5ce88c4a5d61059353ede474788ec9 291 SUPERFAMILY SSF53335 9 266 2.85E-79 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2846 fe9838dbaf26567788bdd679d173a10f 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 266 5.3E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2846 fe9838dbaf26567788bdd679d173a10f 272 Gene3D G3DSA:1.10.3720.10 1 263 3.0E-57 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2846 fe9838dbaf26567788bdd679d173a10f 272 SUPERFAMILY SSF161098 4 272 4.11E-68 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1232 291309891bb15bafc6cf2c6e4cdbf531 415 Gene3D G3DSA:1.25.40.10 338 404 8.7E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1570 6e2ffa7ae8588414d5a3fe70073455e3 487 Pfam PF13586 Transposase DDE domain 363 457 1.6E-24 T 13-10-2018 IPR025668 Transposase DDE domain Spica_1570 6e2ffa7ae8588414d5a3fe70073455e3 487 Pfam PF05598 Transposase domain (DUF772) 53 123 2.1E-14 T 13-10-2018 IPR008490 Transposase InsH, N-terminal Spica_1562 15051592a2f73030213545cee9a54a55 256 Gene3D G3DSA:3.40.50.150 23 254 5.3E-50 T 13-10-2018 Spica_1562 15051592a2f73030213545cee9a54a55 256 Pfam PF01189 16S rRNA methyltransferase RsmB/F 55 252 1.9E-27 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Spica_1562 15051592a2f73030213545cee9a54a55 256 SUPERFAMILY SSF53335 39 254 8.17E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1562 15051592a2f73030213545cee9a54a55 256 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 64 74 4.9E-14 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Spica_1562 15051592a2f73030213545cee9a54a55 256 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 137 149 4.9E-14 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Spica_1562 15051592a2f73030213545cee9a54a55 256 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 187 203 4.9E-14 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Spica_0627 149fa1685d7777880393e506872f9cb4 278 Gene3D G3DSA:2.60.120.10 12 264 5.8E-121 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Spica_0627 149fa1685d7777880393e506872f9cb4 278 Gene3D G3DSA:2.60.120.520 32 144 5.8E-121 T 13-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Spica_0627 149fa1685d7777880393e506872f9cb4 278 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 3 278 56.64 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Spica_0627 149fa1685d7777880393e506872f9cb4 278 PIRSF PIRSF006625 3 278 1.3E-135 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Spica_0627 149fa1685d7777880393e506872f9cb4 278 Pfam PF04962 KduI/IolB family 31 271 2.6E-35 T 13-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Spica_0627 149fa1685d7777880393e506872f9cb4 278 SUPERFAMILY SSF51182 4 262 9.49E-106 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Spica_2241 30bda24d39ec6b155fe2c4b894e52994 133 Gene3D G3DSA:1.10.10.10 19 133 4.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2241 30bda24d39ec6b155fe2c4b894e52994 133 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 2.4E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_2241 30bda24d39ec6b155fe2c4b894e52994 133 SUPERFAMILY SSF46785 15 89 2.73E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Spica_2241 30bda24d39ec6b155fe2c4b894e52994 133 SMART SM00345 26 85 4.2E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Spica_1823 a749c9734f985ff7355fb1378158ab77 157 SUPERFAMILY SSF55804 3 148 1.7E-36 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_1823 a749c9734f985ff7355fb1378158ab77 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 148 9.7E-35 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Spica_1823 a749c9734f985ff7355fb1378158ab77 157 Gene3D G3DSA:3.40.930.10 2 151 1.9E-42 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Spica_0061 a82f77d35b2bd23524784ff81f56f90b 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 275 2.3E-9 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0061 a82f77d35b2bd23524784ff81f56f90b 283 SUPERFAMILY SSF161098 14 283 6.17E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0061 a82f77d35b2bd23524784ff81f56f90b 283 Gene3D G3DSA:1.10.3720.10 6 274 7.7E-47 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2445 d7335bf1edcb7e1c7eb0d2561e15bcb5 313 SUPERFAMILY SSF102114 44 204 3.14E-11 T 13-10-2018 Spica_2445 d7335bf1edcb7e1c7eb0d2561e15bcb5 313 Gene3D G3DSA:3.20.20.70 42 222 6.1E-13 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1154 c83bf32fcd6d7fac6b91cd24fe9eda0d 182 Pfam PF01661 Macro domain 25 141 2.6E-44 T 13-10-2018 IPR002589 Macro domain Spica_1154 c83bf32fcd6d7fac6b91cd24fe9eda0d 182 SUPERFAMILY SSF52949 8 176 4.21E-68 T 13-10-2018 Spica_1154 c83bf32fcd6d7fac6b91cd24fe9eda0d 182 Gene3D G3DSA:3.40.220.10 1 180 4.7E-76 T 13-10-2018 Spica_1154 c83bf32fcd6d7fac6b91cd24fe9eda0d 182 SMART SM00506 8 141 5.6E-52 T 13-10-2018 IPR002589 Macro domain Spica_0828 07144468624c56b9f343077536716769 326 SUPERFAMILY SSF160964 5 79 5.89E-7 T 13-10-2018 Spica_0828 07144468624c56b9f343077536716769 326 Gene3D G3DSA:1.10.3720.10 78 322 1.1E-62 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0828 07144468624c56b9f343077536716769 326 SUPERFAMILY SSF161098 82 311 1.96E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_0828 07144468624c56b9f343077536716769 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 7.2E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_0030 f8e92cb70ca32c6e495afd5e390a5c25 179 PRINTS PR00502 NUDIX hydrolase family signature 84 99 1.3E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0030 f8e92cb70ca32c6e495afd5e390a5c25 179 PRINTS PR00502 NUDIX hydrolase family signature 70 84 1.3E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Spica_0030 f8e92cb70ca32c6e495afd5e390a5c25 179 Gene3D G3DSA:3.90.79.10 42 179 3.6E-25 T 13-10-2018 Spica_0030 f8e92cb70ca32c6e495afd5e390a5c25 179 SUPERFAMILY SSF55811 10 175 1.62E-31 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Spica_0030 f8e92cb70ca32c6e495afd5e390a5c25 179 Pfam PF00293 NUDIX domain 44 172 3.4E-19 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Spica_0346 c3c2ad4efa80220e83e5fe066f4f6514 230 Pfam PF02577 Bifunctional nuclease 14 136 2.9E-39 T 13-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 Spica_0346 c3c2ad4efa80220e83e5fe066f4f6514 230 Gene3D G3DSA:3.10.690.10 2 143 4.7E-42 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Spica_0346 c3c2ad4efa80220e83e5fe066f4f6514 230 Pfam PF02151 UvrB/uvrC motif 199 228 2.3E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 Spica_0346 c3c2ad4efa80220e83e5fe066f4f6514 230 SUPERFAMILY SSF103256 17 137 1.44E-33 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 Spica_0292 d426bce003854e156d5284efbdb8e1a8 384 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 145 375 5.2E-48 T 13-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 Spica_0292 d426bce003854e156d5284efbdb8e1a8 384 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 142 380 4.0E-35 T 13-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 Spica_1573 29bd53207a40677c849f164813f4e6ca 310 SUPERFAMILY SSF74650 7 161 3.3E-11 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Spica_1573 29bd53207a40677c849f164813f4e6ca 310 Gene3D G3DSA:2.70.98.10 12 310 1.3E-27 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Spica_0833 5a335e7bf8361cd5014a8d998a40e3b5 231 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 26 132 7.7E-24 T 13-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 Spica_0833 5a335e7bf8361cd5014a8d998a40e3b5 231 SUPERFAMILY SSF54534 39 230 4.12E-61 T 13-10-2018 Spica_0833 5a335e7bf8361cd5014a8d998a40e3b5 231 Gene3D G3DSA:1.10.287.460 36 94 4.8E-12 T 13-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 Spica_0833 5a335e7bf8361cd5014a8d998a40e3b5 231 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 140 227 6.7E-30 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_0833 5a335e7bf8361cd5014a8d998a40e3b5 231 Gene3D G3DSA:3.10.50.40 95 231 1.5E-58 T 13-10-2018 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 SUPERFAMILY SSF48452 23 232 1.23E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 Pfam PF13432 Tetratricopeptide repeat 108 173 2.5E-7 T 13-10-2018 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 Pfam PF13432 Tetratricopeptide repeat 30 88 0.0087 T 13-10-2018 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 Gene3D G3DSA:1.25.40.10 103 294 2.8E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 Gene3D G3DSA:1.25.40.10 17 102 3.3E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 SMART SM00028 141 174 3.5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 SMART SM00028 25 61 460.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1368 3328c0722e1eb1a504c88115140b089f 333 SMART SM00028 104 137 38.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_2255 35c7f813d79e06d2a8a05075528c7a18 250 SUPERFAMILY SSF89550 4 233 4.58E-59 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Spica_2255 35c7f813d79e06d2a8a05075528c7a18 250 SMART SM00481 5 79 1.4E-9 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_2255 35c7f813d79e06d2a8a05075528c7a18 250 Gene3D G3DSA:3.20.20.140 3 245 4.0E-64 T 13-10-2018 Spica_2255 35c7f813d79e06d2a8a05075528c7a18 250 Pfam PF13263 PHP-associated 175 201 2.2E-5 T 13-10-2018 Spica_2194 e1ea99d4641df1f4a4bcc175db2a9d85 231 SUPERFAMILY SSF52058 57 213 2.45E-13 T 13-10-2018 Spica_2194 e1ea99d4641df1f4a4bcc175db2a9d85 231 Gene3D G3DSA:3.80.10.10 29 220 8.7E-16 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Spica_0820 c3bf023ad913564e11246913e6d7c769 272 Pfam PF01643 Acyl-ACP thioesterase 8 236 1.6E-39 T 13-10-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 Spica_0820 c3bf023ad913564e11246913e6d7c769 272 SUPERFAMILY SSF54637 164 231 7.86E-13 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_0820 c3bf023ad913564e11246913e6d7c769 272 SUPERFAMILY SSF54637 8 135 1.73E-25 T 13-10-2018 IPR029069 HotDog domain superfamily Spica_0820 c3bf023ad913564e11246913e6d7c769 272 Gene3D G3DSA:3.10.129.10 4 271 4.0E-51 T 13-10-2018 Spica_2286 0a7363bc6771c3fcddcde52356bb78a6 310 SUPERFAMILY SSF161098 53 291 4.45E-52 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2286 0a7363bc6771c3fcddcde52356bb78a6 310 Gene3D G3DSA:1.10.3720.10 49 307 5.1E-62 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2286 0a7363bc6771c3fcddcde52356bb78a6 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 295 2.5E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2316 b14866849f1dcc16634acfce158ab5c4 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 327 2.1E-39 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0850 ef523b2b80d4e0984b1d2342fb69a2aa 396 Pfam PF04748 Divergent polysaccharide deacetylase 173 385 9.0E-69 T 13-10-2018 IPR006837 Divergent polysaccharide deacetylase Spica_0850 ef523b2b80d4e0984b1d2342fb69a2aa 396 Gene3D G3DSA:3.20.20.370 167 386 1.2E-71 T 13-10-2018 Spica_0850 ef523b2b80d4e0984b1d2342fb69a2aa 396 SUPERFAMILY SSF88713 169 384 9.12E-58 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Spica_1630 3105b24ca9fd1fed574811ec0753d6cb 338 Pfam PF04620 Flagellar filament outer layer protein Flaa 44 284 6.1E-75 T 13-10-2018 IPR006714 Flagellar filament outer layer protein FlaA GO:0030288|GO:0071973 Spica_0367 5a93305ef8385597a64ac856e7223d1c 328 Hamap MF_01562 UPF0365 protein . 2 327 44.999 T 13-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity Spica_0367 5a93305ef8385597a64ac856e7223d1c 328 Pfam PF12127 SigmaW regulon antibacterial 9 324 6.9E-154 T 13-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity Spica_2304 6d90e68d49a316828d1dca80cbaa40f1 85 Pfam PF13648 Lipocalin-like domain 4 71 3.9E-5 T 13-10-2018 IPR024311 Lipocalin-like domain Spica_1840 7438870247e75d71710397cdcaadcea4 362 Gene3D G3DSA:1.25.40.10 67 249 5.0E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1840 7438870247e75d71710397cdcaadcea4 362 Pfam PF13174 Tetratricopeptide repeat 186 211 0.0053 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1840 7438870247e75d71710397cdcaadcea4 362 SUPERFAMILY SSF48452 75 233 5.69E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2649 cf50b680958da019d607f0d27b36bfef 500 Gene3D G3DSA:3.30.70.1230 89 297 7.6E-10 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_2649 cf50b680958da019d607f0d27b36bfef 500 SUPERFAMILY SSF55073 101 296 2.51E-11 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0871 d1ece61e51ddaf7b9ee0f580c68a773c 568 Pfam PF00361 Proton-conducting membrane transporter 130 411 1.5E-44 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Spica_1051 10ecd207e4a34284904b681d4a83f062 423 Pfam PF03687 Uncharacterised protein family (UPF0164) 53 325 4.9E-51 T 13-10-2018 IPR005362 Uncharacterised protein family UPF0164 Spica_1051 10ecd207e4a34284904b681d4a83f062 423 Gene3D G3DSA:1.25.40.10 358 412 4.1E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2354 3cc8106837057ad3ac16f913c14545a8 333 Pfam PF14057 GGGtGRT protein 4 330 1.3E-196 T 13-10-2018 IPR025964 GGGtGRT protein Spica_2780 3eebfc6f69800a13ea40ea8eb00b38b8 221 Gene3D G3DSA:3.40.50.300 1 184 2.2E-40 T 13-10-2018 Spica_2780 3eebfc6f69800a13ea40ea8eb00b38b8 221 Pfam PF13189 Cytidylate kinase-like family 3 166 3.5E-30 T 13-10-2018 Spica_2813 ed866a110e9d49dd3d4391f8f986847a 389 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 375 6.6E-41 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_2173 86237042c6f636f9c1e83aeb53a9462e 197 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 108 166 3.9E-9 T 13-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF Spica_2173 86237042c6f636f9c1e83aeb53a9462e 197 Pfam PF08044 Domain of unknown function (DUF1707) 3 50 2.5E-11 T 13-10-2018 IPR012551 Protein of unknown function DUF1707 Spica_1265 259a19aadf14cd4404ee3db001085382 138 Gene3D G3DSA:3.30.2130.10 1 138 9.9E-50 T 13-10-2018 Spica_1265 259a19aadf14cd4404ee3db001085382 138 SUPERFAMILY SSF55021 2 69 2.89E-16 T 13-10-2018 Spica_1265 259a19aadf14cd4404ee3db001085382 138 SUPERFAMILY SSF55021 71 136 8.95E-11 T 13-10-2018 Spica_1265 259a19aadf14cd4404ee3db001085382 138 Pfam PF01842 ACT domain 5 53 6.4E-8 T 13-10-2018 IPR002912 ACT domain Spica_2057 814e58c3631d8281348127aabccd2856 235 Pfam PF10016 Predicted secreted protein (DUF2259) 42 234 2.3E-53 T 13-10-2018 IPR018725 Protein of unknown function DUF2259, secreted Spica_1652 baf61823d83c58db7c3a3c3e7d2601d4 305 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 6 266 1.3E-54 T 13-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 Spica_1652 baf61823d83c58db7c3a3c3e7d2601d4 305 SUPERFAMILY SSF52540 1 262 6.69E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1652 baf61823d83c58db7c3a3c3e7d2601d4 305 Gene3D G3DSA:3.40.50.300 1 301 1.3E-63 T 13-10-2018 Spica_1652 baf61823d83c58db7c3a3c3e7d2601d4 305 Pfam PF02374 Anion-transporting ATPase 3 263 2.4E-51 T 13-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 Spica_1774 ce995680a6eb4fe22f2551ff1b14f59c 124 SUPERFAMILY SSF54427 13 121 1.21E-6 T 13-10-2018 IPR032710 NTF2-like domain superfamily Spica_1774 ce995680a6eb4fe22f2551ff1b14f59c 124 Gene3D G3DSA:3.10.450.50 10 124 1.0E-8 T 13-10-2018 Spica_0758 5cd8e411ae9f26a7067e653ad5223f3d 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 73 350 4.2E-40 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0921 fd01b79e5bff9302ef5befc7938113b2 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 294 1.6E-43 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0852 c8f5450548a6d4b1a5d48fa29f8f49ec 318 SUPERFAMILY SSF52540 1 306 4.86E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0852 c8f5450548a6d4b1a5d48fa29f8f49ec 318 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 270 6.2E-17 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spica_1364 6efe7cd2fb2dbf28cec91b577a8ed44c 703 Gene3D G3DSA:3.40.50.410 34 271 5.7E-14 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1364 6efe7cd2fb2dbf28cec91b577a8ed44c 703 SUPERFAMILY SSF53300 39 192 3.26E-16 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Spica_1364 6efe7cd2fb2dbf28cec91b577a8ed44c 703 Pfam PF13519 von Willebrand factor type A domain 41 147 2.7E-9 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_1364 6efe7cd2fb2dbf28cec91b577a8ed44c 703 SMART SM00327 38 200 3.2E-4 T 13-10-2018 IPR002035 von Willebrand factor, type A Spica_0744 ad9a1f5637c75399aa5cd1e194dcaa73 419 SUPERFAMILY SSF56300 152 406 1.82E-38 T 13-10-2018 Spica_0744 ad9a1f5637c75399aa5cd1e194dcaa73 419 Pfam PF00149 Calcineurin-like phosphoesterase 152 345 2.4E-17 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Spica_0744 ad9a1f5637c75399aa5cd1e194dcaa73 419 Gene3D G3DSA:3.60.21.10 157 416 3.6E-26 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Spica_0237 976c39cfcfe879301b84826f51b26dea 247 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 62 228 1.7E-32 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 Spica_1725 1ac905a8d2bb6e4976ee8cd27479b719 205 SMART SM00900 98 195 4.3E-22 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_1725 1ac905a8d2bb6e4976ee8cd27479b719 205 Pfam PF04205 FMN-binding domain 98 190 3.7E-15 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_1725 1ac905a8d2bb6e4976ee8cd27479b719 205 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 3 197 20.737 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Spica_1725 1ac905a8d2bb6e4976ee8cd27479b719 205 PIRSF PIRSF006091 1 204 4.4E-26 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Spica_2440 1e5a7ae9bb0b06e38f422f0093125a31 109 Gene3D G3DSA:3.30.420.10 47 105 8.0E-7 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Spica_2440 1e5a7ae9bb0b06e38f422f0093125a31 109 SUPERFAMILY SSF53098 48 96 2.28E-9 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Spica_0680 2b2e76200af5d605d08b2d9052b6b345 179 Gene3D G3DSA:1.20.1260.10 1 173 5.1E-51 T 13-10-2018 IPR012347 Ferritin-like Spica_0680 2b2e76200af5d605d08b2d9052b6b345 179 SUPERFAMILY SSF47240 1 160 2.24E-56 T 13-10-2018 IPR009078 Ferritin-like superfamily Spica_0680 2b2e76200af5d605d08b2d9052b6b345 179 Pfam PF00210 Ferritin-like domain 9 142 1.5E-41 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Spica_0319 025590d8f2e2cce6fbfb781eb8a61c24 744 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 486 665 6.6E-30 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_0319 025590d8f2e2cce6fbfb781eb8a61c24 744 Gene3D G3DSA:3.30.70.1230 482 683 3.1E-60 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0319 025590d8f2e2cce6fbfb781eb8a61c24 744 SUPERFAMILY SSF55073 487 669 2.51E-53 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_0319 025590d8f2e2cce6fbfb781eb8a61c24 744 SMART SM00044 456 649 1.5E-13 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 Spica_1856 91e262d2821e34acdc9245f81aab3ddc 112 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 12 106 1.4E-19 T 13-10-2018 IPR009241 Toxin HigB-like Spica_1188 e5a707eff153031f2b723adacfb18a6a 181 Pfam PF01625 Peptide methionine sulfoxide reductase 9 161 1.3E-63 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Spica_1188 e5a707eff153031f2b723adacfb18a6a 181 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 7 166 36.405 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Spica_1188 e5a707eff153031f2b723adacfb18a6a 181 Gene3D G3DSA:3.30.1060.10 1 169 1.1E-67 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Spica_1188 e5a707eff153031f2b723adacfb18a6a 181 SUPERFAMILY SSF55068 5 171 2.09E-71 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Spica_1188 e5a707eff153031f2b723adacfb18a6a 181 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 161 1.1E-57 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Spica_0777 15e2cf3340e20e71b219e3fcb218c876 136 SUPERFAMILY SSF52218 18 132 3.49E-5 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Spica_1055 3ee9aa8cc2282d377f8a324272429bed 422 SUPERFAMILY SSF53850 28 418 2.26E-44 T 13-10-2018 Spica_1055 3ee9aa8cc2282d377f8a324272429bed 422 Gene3D G3DSA:3.40.190.10 28 421 4.9E-48 T 13-10-2018 Spica_1055 3ee9aa8cc2282d377f8a324272429bed 422 Pfam PF13416 Bacterial extracellular solute-binding protein 46 351 6.0E-25 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Spica_0115 d66ebfac9b55b46ecbc47f7cad279283 74 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 17 61 1.8E-8 T 13-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system Spica_2299 8ca42410976aa7592657915af5e4e075 229 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 127 213 3.1E-15 T 13-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 Spica_2299 8ca42410976aa7592657915af5e4e075 229 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 89 2.0E-15 T 13-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 Spica_2693 f2b16934d4aa10c2c28aaf0ad7a5223f 102 SUPERFAMILY SSF81301 13 100 1.31E-14 T 13-10-2018 Spica_2693 f2b16934d4aa10c2c28aaf0ad7a5223f 102 Gene3D G3DSA:3.30.460.10 2 102 1.3E-21 T 13-10-2018 Spica_2693 f2b16934d4aa10c2c28aaf0ad7a5223f 102 Pfam PF01909 Nucleotidyltransferase domain 17 83 1.5E-9 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spica_0521 cd7010b3940cdccbfbea26c901b23882 379 Gene3D G3DSA:3.40.50.620 8 276 8.7E-19 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0521 cd7010b3940cdccbfbea26c901b23882 379 Pfam PF02540 NAD synthase 58 183 7.7E-6 T 13-10-2018 IPR022310 NAD/GMP synthase Spica_0521 cd7010b3940cdccbfbea26c901b23882 379 SUPERFAMILY SSF52402 56 316 5.95E-31 T 13-10-2018 Spica_0521 cd7010b3940cdccbfbea26c901b23882 379 TIGRFAM TIGR03573 WbuX: N-acetyl sugar amidotransferase 7 345 2.8E-94 T 13-10-2018 IPR020022 N-acetyl sugar amidotransferase Spica_0170 2151f2899dc23f2141386a7c54c6835a 285 Pfam PF08543 Phosphomethylpyrimidine kinase 29 272 4.0E-92 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Spica_0170 2151f2899dc23f2141386a7c54c6835a 285 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 22 274 4.2E-98 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Spica_0170 2151f2899dc23f2141386a7c54c6835a 285 SUPERFAMILY SSF53613 21 277 4.05E-78 T 13-10-2018 IPR029056 Ribokinase-like Spica_0170 2151f2899dc23f2141386a7c54c6835a 285 Gene3D G3DSA:3.40.1190.20 1 282 1.2E-98 T 13-10-2018 IPR029056 Ribokinase-like Spica_0093 31b233fb87a0d1f36b5d1b15facfaecf 109 Gene3D G3DSA:3.30.460.10 5 109 3.9E-16 T 13-10-2018 Spica_0093 31b233fb87a0d1f36b5d1b15facfaecf 109 Pfam PF01909 Nucleotidyltransferase domain 31 93 1.5E-5 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Spica_0093 31b233fb87a0d1f36b5d1b15facfaecf 109 SUPERFAMILY SSF81301 17 106 4.73E-13 T 13-10-2018 Spica_2863 4149f63804bd40845adb0b0f3128cca6 97 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 12 69 4.1E-13 T 13-10-2018 Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 Gene3D G3DSA:3.30.465.10 2 176 1.2E-47 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 174 1.3E-42 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 SUPERFAMILY SSF55447 179 270 1.57E-13 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 269 8.7E-5 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 Gene3D G3DSA:3.30.390.50 179 272 3.2E-11 T 13-10-2018 Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 SMART SM01092 181 270 1.2E-11 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spica_0615 557f0cc17c23a4a6b05b6816e707f1e8 272 SUPERFAMILY SSF56176 3 174 2.89E-44 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Spica_0249 c1421836a7e1af5e7b2b28cdcf5bbcf5 279 SMART SM00563 90 207 1.8E-18 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_0249 c1421836a7e1af5e7b2b28cdcf5bbcf5 279 SUPERFAMILY SSF69593 40 253 3.01E-26 T 13-10-2018 Spica_0249 c1421836a7e1af5e7b2b28cdcf5bbcf5 279 Pfam PF01553 Acyltransferase 76 204 3.2E-14 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Spica_1872 c9289abed1826318a0deb26c818de4a7 160 Pfam PF03773 Predicted permease 38 154 5.0E-8 T 13-10-2018 IPR005524 Predicted permease DUF318 Spica_1323 027b94adaad1d8ccabefc05bf04fbdad 359 Pfam PF00953 Glycosyl transferase family 4 81 237 7.8E-39 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Spica_1323 027b94adaad1d8ccabefc05bf04fbdad 359 ProSitePatterns PS01348 MraY family signature 2. 156 167 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_0868 70e6ba929719de13c0c93a2d4cfc6831 76 Gene3D G3DSA:1.20.120.1200 1 75 3.4E-5 T 13-10-2018 Spica_0868 70e6ba929719de13c0c93a2d4cfc6831 76 Pfam PF13244 Domain of unknown function (DUF4040) 7 72 7.6E-20 T 13-10-2018 IPR025383 Domain of unknown function DUF4040 Spica_2383 9a89dfaef70958d47792b926152e2ced 433 Pfam PF00155 Aminotransferase class I and II 73 421 2.4E-25 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Spica_2383 9a89dfaef70958d47792b926152e2ced 433 Gene3D G3DSA:3.40.640.10 1 325 1.0E-67 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Spica_2383 9a89dfaef70958d47792b926152e2ced 433 SUPERFAMILY SSF53383 31 415 8.82E-48 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2383 9a89dfaef70958d47792b926152e2ced 433 Gene3D G3DSA:3.90.1150.10 327 429 2.3E-31 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Spica_0942 a7546caedddc823650c40b557576c1fb 259 Pfam PF04474 Protein of unknown function (DUF554) 2 243 8.5E-71 T 13-10-2018 IPR007563 Protein of unknown function DUF554 Spica_2062 ab1974519efd87dad59725bb1f5744e8 239 Pfam PF13367 Protease prsW family 36 220 1.0E-8 T 13-10-2018 IPR026898 Protease PrsW GO:0008233 Spica_0460 47f6a1f75d456b570855df7482f803ce 229 SUPERFAMILY SSF89392 33 221 5.49E-20 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX Spica_0460 47f6a1f75d456b570855df7482f803ce 229 Gene3D G3DSA:2.50.20.10 27 222 1.4E-28 T 13-10-2018 Spica_0460 47f6a1f75d456b570855df7482f803ce 229 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 59 211 2.9E-10 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like Spica_1870 f8a40eac1bbedef115422d22b82f4ed2 131 Pfam PF08859 DGC domain 15 113 2.0E-25 T 13-10-2018 IPR014958 DGC Spica_0013 481c046aa90fff201ed8faf8de9f6382 94 SUPERFAMILY SSF101498 3 90 1.16E-7 T 13-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily Spica_0013 481c046aa90fff201ed8faf8de9f6382 94 Pfam PF04316 Anti-sigma-28 factor, FlgM 31 90 1.7E-10 T 13-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal Spica_2683 bccf3f2ae46331cc541dd32a2f7e12fd 339 Pfam PF03824 High-affinity nickel-transport protein 109 217 1.0E-11 T 13-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 Spica_2683 bccf3f2ae46331cc541dd32a2f7e12fd 339 Pfam PF03824 High-affinity nickel-transport protein 233 326 6.5E-8 T 13-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 Spica_1235 16a5cc9f031abc9f8a3bb7d23c1ba5d1 497 Pfam PF08308 PEGA domain 333 369 2.0E-6 T 13-10-2018 IPR013229 PEGA Spica_0693 8d4a4bc1288c1cf2f67ae5596c528552 201 PIRSF PIRSF037394 4 196 3.8E-49 T 13-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted Spica_0693 8d4a4bc1288c1cf2f67ae5596c528552 201 Pfam PF09819 ABC-type cobalt transport system, permease component 14 130 2.0E-33 T 13-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted Spica_1292 d06f7775f44fc2132b78a6b90bfc25cc 558 Pfam PF01973 Protein of unknown function DUF115 211 370 3.1E-29 T 13-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Spica_1166 32b0b9e6109d542c055a2bbc69e90d6c 480 Pfam PF03961 Flagellar Assembly Protein A 33 469 9.3E-81 T 13-10-2018 IPR005646 Flagellar assembly protein A Spica_0314 b41582bac5e083b7619494c9e89e99d7 162 Pfam PF08905 Domain of unknown function (DUF1850) 60 140 1.7E-18 T 13-10-2018 IPR015001 Protein of unknown function DUF1850 Spica_0475 4e87168083fd5fdb55b0a4fbece775a1 182 SUPERFAMILY SSF55874 51 112 3.14E-6 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0475 4e87168083fd5fdb55b0a4fbece775a1 182 Gene3D G3DSA:3.30.565.10 24 125 1.0E-7 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2310 2d7cd7fe015c3f732125bdcafda63b31 382 Pfam PF01882 Protein of unknown function DUF58 188 261 2.0E-15 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Spica_0357 d331256cc6046cf7f9076c54a41ef4f3 397 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 51 348 1.1E-5 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Spica_0357 d331256cc6046cf7f9076c54a41ef4f3 397 SUPERFAMILY SSF56219 46 394 6.77E-31 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Spica_2256 b76e3d1e06c460332d6192dfc972ed1f 468 PIRSF PIRSF006603 18 468 4.0E-70 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2256 b76e3d1e06c460332d6192dfc972ed1f 468 TIGRFAM TIGR00797 matE: MATE efflux family protein 39 439 4.3E-50 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2256 b76e3d1e06c460332d6192dfc972ed1f 468 Pfam PF01554 MatE 265 426 4.1E-21 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2256 b76e3d1e06c460332d6192dfc972ed1f 468 Pfam PF01554 MatE 39 199 2.3E-23 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_0128 d118f0f3a6c5f55ee4f693c9ca8f92b2 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 311 1.3E-41 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0533 ac17c5da772d7e8e7876074716c465c3 87 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 26 57 7.1E-6 T 13-10-2018 Spica_0533 ac17c5da772d7e8e7876074716c465c3 87 SUPERFAMILY SSF143120 3 77 7.46E-16 T 13-10-2018 IPR036165 YefM-like superfamily Spica_0533 ac17c5da772d7e8e7876074716c465c3 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 63 1.2E-7 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Spica_0303 f6e6dbc0b4280e3d11a8262f6836669e 315 SUPERFAMILY SSF56281 33 290 1.21E-23 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0303 f6e6dbc0b4280e3d11a8262f6836669e 315 Gene3D G3DSA:3.60.15.10 26 315 3.3E-66 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0303 f6e6dbc0b4280e3d11a8262f6836669e 315 Pfam PF00753 Metallo-beta-lactamase superfamily 40 100 2.6E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_1296 bd6359d92b8bbf567348bca5fe3cbb69 151 Pfam PF04977 Septum formation initiator 15 90 1.8E-8 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC Spica_1349 1e3d544af97dc322a3185527bccee561 162 Gene3D G3DSA:3.30.750.24 4 109 1.9E-11 T 13-10-2018 IPR036513 STAS domain superfamily Spica_1349 1e3d544af97dc322a3185527bccee561 162 SUPERFAMILY SSF52091 9 105 2.55E-11 T 13-10-2018 IPR036513 STAS domain superfamily Spica_1046 95f39b26dc562d3ad8daa1166f477856 388 Gene3D G3DSA:3.30.60.20 212 286 6.4E-5 T 13-10-2018 Spica_1046 95f39b26dc562d3ad8daa1166f477856 388 SUPERFAMILY SSF52540 36 202 1.17E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1046 95f39b26dc562d3ad8daa1166f477856 388 Pfam PF00265 Thymidine kinase 150 252 1.6E-5 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Spica_1501 0e87bd32a25a26a6f09ee162c528b2a3 200 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 198 17.792 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1501 0e87bd32a25a26a6f09ee162c528b2a3 200 Pfam PF01813 ATP synthase subunit D 10 192 6.5E-43 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_1501 0e87bd32a25a26a6f09ee162c528b2a3 200 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 196 8.7E-48 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 Spica_0809 97e46f9a3bc854954ebfde778a15baf3 226 SUPERFAMILY SSF50974 130 189 1.57E-8 T 13-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 Spica_0809 97e46f9a3bc854954ebfde778a15baf3 226 Gene3D G3DSA:2.130.10.10 127 192 4.5E-10 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Spica_2527 ceb54988f74cfa73c02e7c3df9c4588e 327 Pfam PF03547 Membrane transport protein 25 173 7.6E-16 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Spica_2527 ceb54988f74cfa73c02e7c3df9c4588e 327 Pfam PF03547 Membrane transport protein 179 320 5.8E-18 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Spica_1391 adb178cf84975823cb2409eeadc9642f 283 Pfam PF02591 C4-type zinc ribbon domain 200 232 6.8E-13 T 13-10-2018 IPR003743 C4-type zinc ribbon domain Spica_2768 b39bb8eefc6cd3a6954396ac3f6a1ca2 263 Pfam PF00912 Transglycosylase 93 260 4.5E-42 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_2768 b39bb8eefc6cd3a6954396ac3f6a1ca2 263 SUPERFAMILY SSF53955 87 261 2.31E-48 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Spica_2768 b39bb8eefc6cd3a6954396ac3f6a1ca2 263 Gene3D G3DSA:1.10.3810.10 84 263 9.6E-46 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Spica_1654 3b2d004fbcd0873a5dea8afad3197253 93 SUPERFAMILY SSF117916 8 77 9.16E-6 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_1654 3b2d004fbcd0873a5dea8afad3197253 93 Gene3D G3DSA:3.30.300.130 3 93 3.7E-7 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Spica_2452 1c5a4867581819b4fda14e8c2619c0ab 288 SUPERFAMILY SSF161098 16 287 1.18E-52 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2452 1c5a4867581819b4fda14e8c2619c0ab 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 282 7.7E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2452 1c5a4867581819b4fda14e8c2619c0ab 288 Gene3D G3DSA:1.10.3720.10 7 279 1.4E-58 T 13-10-2018 IPR035906 MetI-like superfamily Spica_1290 15e515158cd2a4b07b180b9cac5860ca 403 SUPERFAMILY SSF55073 249 388 1.8E-7 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1290 15e515158cd2a4b07b180b9cac5860ca 403 Gene3D G3DSA:3.30.70.270 244 395 2.0E-6 T 13-10-2018 Spica_0695 9b16301ed82ab823a70cc444f6e8af93 120 Gene3D G3DSA:3.30.750.24 21 120 2.4E-15 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0695 9b16301ed82ab823a70cc444f6e8af93 120 Pfam PF01740 STAS domain 29 116 5.0E-12 T 13-10-2018 IPR002645 STAS domain Spica_0695 9b16301ed82ab823a70cc444f6e8af93 120 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 28 119 1.6E-17 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 Spica_0695 9b16301ed82ab823a70cc444f6e8af93 120 SUPERFAMILY SSF52091 27 118 3.14E-15 T 13-10-2018 IPR036513 STAS domain superfamily Spica_0523 8fdc01c650af87de2128f6f2771829a9 254 Pfam PF00977 Histidine biosynthesis protein 5 231 1.9E-63 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Spica_0523 8fdc01c650af87de2128f6f2771829a9 254 SUPERFAMILY SSF51366 1 234 1.18E-61 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Spica_0523 8fdc01c650af87de2128f6f2771829a9 254 Gene3D G3DSA:3.20.20.70 1 244 6.2E-79 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_0315 8c226793870b4881425260fe0e7ca522 672 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 643 3.3E-228 T 13-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ Spica_0315 8c226793870b4881425260fe0e7ca522 672 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 126 575 9.0E-95 T 13-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Spica_1631 8b253d9937e999eb3a6029162c711146 175 Pfam PF10646 Sporulation and spore germination 53 160 9.1E-6 T 13-10-2018 IPR019606 GerMN domain Spica_2142 b748a12d5da0d82f14297545b15b0658 282 Gene3D G3DSA:1.10.3720.10 30 278 1.0E-46 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2142 b748a12d5da0d82f14297545b15b0658 282 SUPERFAMILY SSF161098 29 275 6.07E-53 T 13-10-2018 IPR035906 MetI-like superfamily Spica_2142 b748a12d5da0d82f14297545b15b0658 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 281 1.5E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Spica_2767 f11d290764b73e095b6140177fd3037a 63 SUPERFAMILY SSF57802 3 33 2.67E-5 T 13-10-2018 Spica_2767 f11d290764b73e095b6140177fd3037a 63 Gene3D G3DSA:2.20.28.100 1 33 5.1E-6 T 13-10-2018 IPR038094 Desulforodoxin domain superfamily Spica_1178 0a53f20bd3c83c0d97a447ad27704832 89 Pfam PF13740 ACT domain 4 77 1.2E-15 T 13-10-2018 Spica_1178 0a53f20bd3c83c0d97a447ad27704832 89 SUPERFAMILY SSF55021 2 83 1.16E-21 T 13-10-2018 Spica_1178 0a53f20bd3c83c0d97a447ad27704832 89 Gene3D G3DSA:3.30.70.260 1 89 1.7E-30 T 13-10-2018 Spica_1178 0a53f20bd3c83c0d97a447ad27704832 89 Hamap MF_01054 UPF0237 protein . 1 89 25.877 T 13-10-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type Spica_0822 cad6c79cb274873cf9dc4d66997d840b 394 Pfam PF03773 Predicted permease 40 391 9.6E-76 T 13-10-2018 IPR005524 Predicted permease DUF318 Spica_0729 a7db0ab856e86bd77c64db534655fbb9 99 Gene3D G3DSA:3.30.70.120 1 94 3.5E-9 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_1270 833e466af8b83cab0d43bcd22cbbad6e 315 SUPERFAMILY SSF53474 3 314 6.57E-38 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_1270 833e466af8b83cab0d43bcd22cbbad6e 315 Gene3D G3DSA:3.40.50.1820 1 315 6.5E-57 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_1270 833e466af8b83cab0d43bcd22cbbad6e 315 Pfam PF12146 Serine aminopeptidase, S33 26 297 1.5E-56 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Spica_2516 c614f9613c4f26d3315a89fea9a5de0a 481 PIRSF PIRSF006247 1 481 9.7E-183 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 Spica_2516 c614f9613c4f26d3315a89fea9a5de0a 481 Pfam PF02386 Cation transport protein 58 276 7.0E-40 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Spica_2516 c614f9613c4f26d3315a89fea9a5de0a 481 Pfam PF02386 Cation transport protein 299 475 3.9E-25 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 Spica_2516 c614f9613c4f26d3315a89fea9a5de0a 481 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 464 3.1E-102 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 Spica_1212 dbd4880a351bd547d24a1565e403b8f8 137 Pfam PF12821 Threonine/Serine exporter, ThrE 3 129 3.5E-32 T 13-10-2018 IPR024528 Threonine/Serine exporter, ThrE Spica_2362 d377ea21d705cf606fc98a4baf858c7c 63 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 46 3.9E-16 T 13-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB Spica_0779 b4a75501bc6c8b7972ebb38c5c5cc0ee 568 Pfam PF17239 Family of unknown function (DUF5312) 9 560 1.8E-198 T 13-10-2018 IPR035196 Protein of unknown function DUF5312 Spica_0649 ade341e66e351b27957a80fa65a7d742 199 SMART SM00900 94 187 2.7E-14 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_0649 ade341e66e351b27957a80fa65a7d742 199 PIRSF PIRSF006091 1 197 1.2E-30 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Spica_0649 ade341e66e351b27957a80fa65a7d742 199 Pfam PF04205 FMN-binding domain 95 183 9.7E-17 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 Spica_0649 ade341e66e351b27957a80fa65a7d742 199 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 1 189 19.7 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 Spica_1828 2fa50574a65eda6f4cf6aeb23250e3e0 183 SUPERFAMILY SSF109604 24 157 5.1E-15 T 13-10-2018 Spica_1828 2fa50574a65eda6f4cf6aeb23250e3e0 183 Gene3D G3DSA:1.10.3210.10 16 172 2.2E-10 T 13-10-2018 Spica_1536 0522b662250185aa8763610a93a73c73 65 Pfam PF06289 Flagellar protein (FlbD) 1 58 2.0E-25 T 13-10-2018 IPR009384 Swarming motility protein SwrD-like Spica_2135 cab93781b2c51cdefa3d8e0decb28f5d 267 Pfam PF06182 ABC-2 family transporter protein 41 266 1.2E-56 T 13-10-2018 IPR010390 Protein of unknown function DUF990 Spica_2563 ac8c2f108635a136a2d2df3b5f71fd25 870 SMART SM00729 383 596 7.4E-8 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Spica_2563 ac8c2f108635a136a2d2df3b5f71fd25 870 SUPERFAMILY SSF102114 359 580 1.96E-16 T 13-10-2018 Spica_0183 b26d328e3ce08840af1c08253c3a5869 457 Gene3D G3DSA:3.40.50.11440 18 282 2.7E-54 T 13-10-2018 Spica_0183 b26d328e3ce08840af1c08253c3a5869 457 Gene3D G3DSA:3.90.226.30 283 445 3.2E-34 T 13-10-2018 Spica_0183 b26d328e3ce08840af1c08253c3a5869 457 Pfam PF09861 Domain of unknown function (DUF2088) 46 196 1.1E-8 T 13-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 Spica_0925 feedb2ad9a4b0197f1cd244ec232365c 539 SUPERFAMILY SSF48452 384 528 2.15E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0925 feedb2ad9a4b0197f1cd244ec232365c 539 SMART SM00028 492 525 0.0053 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_0925 feedb2ad9a4b0197f1cd244ec232365c 539 SMART SM00028 452 488 37.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1484 e9163f283374a6c72f8ad10a11a4d43a 101 SUPERFAMILY SSF52833 17 88 4.31E-12 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Spica_1484 e9163f283374a6c72f8ad10a11a4d43a 101 Gene3D G3DSA:3.40.30.10 2 98 1.1E-18 T 13-10-2018 Spica_1484 e9163f283374a6c72f8ad10a11a4d43a 101 Pfam PF00462 Glutaredoxin 19 82 2.0E-10 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Spica_1962 256a3872c2af04d5c312568429800a15 196 Pfam PF02325 YGGT family 13 80 8.7E-16 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 Spica_2446 290eaf409c8dc817883331bab4e35b18 255 SUPERFAMILY SSF48452 153 250 2.19E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2446 290eaf409c8dc817883331bab4e35b18 255 Gene3D G3DSA:1.25.40.10 106 255 7.1E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1431 343640037826c847c1ad745374d6fb28 428 SUPERFAMILY SSF51905 3 426 6.17E-18 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2652 bbbb1b7b1cb10b3b56a3a209f63ec899 325 Pfam PF07670 Nucleoside recognition 29 122 1.6E-5 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Spica_1700 0369b32629e983b737c46f5dae14c642 176 Pfam PF06005 Cell division protein ZapB 3 71 2.3E-14 T 13-10-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 Spica_0863 bf7db4a99e6e9bcd6b830b279d76eb58 116 SUPERFAMILY SSF54913 4 109 2.32E-10 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_0700 8daef89f8fec9b1f311772b7f067ef15 101 Gene3D G3DSA:3.40.30.10 2 73 5.0E-5 T 13-10-2018 Spica_0867 26d3901cbefa7bf17465236a45f9e5c0 106 Pfam PF03334 Na+/H+ antiporter subunit 15 91 3.7E-18 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 Spica_2007 801f4c786a48553d841fc55e4e2ebcec 394 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 382 5.3E-38 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_1107 93b71ddaa175e6620992383da1aca7d9 153 Pfam PF03477 ATP cone domain 50 138 5.7E-21 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Spica_1107 93b71ddaa175e6620992383da1aca7d9 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 149 8.9E-56 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Spica_1107 93b71ddaa175e6620992383da1aca7d9 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 77.848 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Spica_0749 c71d0c111664d98b4d1a12a3550da269 470 Pfam PF08239 Bacterial SH3 domain 125 186 1.4E-9 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type Spica_0749 c71d0c111664d98b4d1a12a3550da269 470 Gene3D G3DSA:2.30.30.40 114 189 8.0E-7 T 13-10-2018 Spica_0103 37c9ae87e1321bf77c344395ebcfde4a 203 Pfam PF14335 Domain of unknown function (DUF4391) 2 199 2.4E-47 T 13-10-2018 IPR025503 Protein of unknown function DUF4391 Spica_1272 66e81258dca7af7323fb553e2e172da3 392 Gene3D G3DSA:1.25.40.10 266 392 2.0E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1272 66e81258dca7af7323fb553e2e172da3 392 SMART SM00028 312 345 4.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1272 66e81258dca7af7323fb553e2e172da3 392 SMART SM00028 346 379 53.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1272 66e81258dca7af7323fb553e2e172da3 392 SMART SM00028 278 311 61.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Spica_1272 66e81258dca7af7323fb553e2e172da3 392 SUPERFAMILY SSF48452 277 382 4.55E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_1977 ba538acb0c74e99571875c00a87fa775 178 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 11 140 1.9E-8 T 13-10-2018 IPR018639 Domain of unknown function DUF2062 Spica_1977 ba538acb0c74e99571875c00a87fa775 178 TIGRFAM TIGR03546 TIGR03546: TIGR03546 family protein 5 155 1.3E-41 T 13-10-2018 IPR019935 Conserved hypothetical protein CHP03546 Spica_2331 51290f81fc2b36cd71ceab8d83df3ecd 325 SUPERFAMILY SSF52374 104 285 4.07E-9 T 13-10-2018 Spica_2331 51290f81fc2b36cd71ceab8d83df3ecd 325 Gene3D G3DSA:3.40.50.620 105 287 5.6E-15 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0181 78748726f77532be28eb3df88161f10e 67 Pfam PF04102 SlyX 4 67 1.4E-16 T 13-10-2018 IPR007236 SlyX Spica_2476 683facab39a155bb33a64195c2bd6c93 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 120 18.248 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spica_2476 683facab39a155bb33a64195c2bd6c93 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 115 2.0E-25 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spica_2476 683facab39a155bb33a64195c2bd6c93 132 TIGRFAM TIGR00494 crcB: protein CrcB 4 117 1.4E-32 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Spica_1642 71486d3040135efdaefd4d932a287435 307 Gene3D G3DSA:3.30.70.1230 132 302 1.6E-9 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1642 71486d3040135efdaefd4d932a287435 307 SUPERFAMILY SSF55073 129 240 9.89E-9 T 13-10-2018 IPR029787 Nucleotide cyclase Spica_1871 b99c2ffd24d6b61d701c6132b428bf74 178 Pfam PF03773 Predicted permease 43 172 1.3E-11 T 13-10-2018 IPR005524 Predicted permease DUF318 Spica_2051 77ee0a09fdf02a666c85d8be80ee8b3c 706 Pfam PF01136 Peptidase family U32 77 289 1.2E-77 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 Spica_2732 c5431f4770a077ecdaaf4a352c5ded23 448 Pfam PF06245 Protein of unknown function (DUF1015) 19 443 6.9E-72 T 13-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 Spica_0936 e0c2e6ba9954e5ce1298e75f2befc140 164 Pfam PF12801 4Fe-4S binding domain 111 148 2.3E-5 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0936 e0c2e6ba9954e5ce1298e75f2befc140 164 Pfam PF12801 4Fe-4S binding domain 27 67 0.0011 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1960 149287aa63a67ebd00660ef423f9f4f9 76 Pfam PF12646 Domain of unknown function (DUF3783) 4 65 2.0E-19 T 13-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 Spica_2829 53cb254a519be755800b5e2aa6aa6d3c 349 Pfam PF10974 Protein of unknown function (DUF2804) 17 347 4.6E-67 T 13-10-2018 IPR021243 Protein of unknown function DUF2804 Spica_1504 a6685fd756147c163c8673feb8de9620 201 Pfam PF10962 Protein of unknown function (DUF2764) 126 183 2.9E-5 T 13-10-2018 IPR024492 Protein of unknown function DUF2764 Spica_2069 758d14afc093cb998385bbe6a2e3b172 227 Pfam PF16161 Domain of unknown function (DUF4867) 19 222 1.3E-64 T 13-10-2018 IPR032358 Protein of unknown function DUF4867 Spica_2145 9ac1a5a749bcc4db569f6f0735852437 424 Pfam PF03600 Citrate transporter 25 366 7.6E-36 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Spica_2145 9ac1a5a749bcc4db569f6f0735852437 424 PRINTS PR00758 Arsenical pump membrane protein signature 98 122 1.1E-11 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_2145 9ac1a5a749bcc4db569f6f0735852437 424 PRINTS PR00758 Arsenical pump membrane protein signature 362 387 1.1E-11 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_2145 9ac1a5a749bcc4db569f6f0735852437 424 PRINTS PR00758 Arsenical pump membrane protein signature 275 299 1.1E-11 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_2145 9ac1a5a749bcc4db569f6f0735852437 424 PRINTS PR00758 Arsenical pump membrane protein signature 320 342 1.1E-11 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 Spica_1273 3e8c32e015c51a71001833a5f941af53 288 SUPERFAMILY SSF52540 16 144 1.04E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1273 3e8c32e015c51a71001833a5f941af53 288 Gene3D G3DSA:3.40.50.300 13 177 4.0E-5 T 13-10-2018 Spica_1876 aa8d9f8052ba83e9c8c638c4c258bdee 494 Gene3D G3DSA:3.20.20.70 38 417 2.1E-111 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Spica_1876 aa8d9f8052ba83e9c8c638c4c258bdee 494 SMART SM00876 290 406 7.5E-20 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Spica_1876 aa8d9f8052ba83e9c8c638c4c258bdee 494 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 51 492 4.4E-145 T 13-10-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM Spica_1876 aa8d9f8052ba83e9c8c638c4c258bdee 494 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 308 404 3.1E-21 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Spica_1876 aa8d9f8052ba83e9c8c638c4c258bdee 494 SUPERFAMILY SSF102114 66 367 8.24E-46 T 13-10-2018 Spica_1131 0fcceba339ef7a278f95fef90f7c9ff1 371 SUPERFAMILY SSF50939 65 164 3.43E-5 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Spica_1724 ac3876e835ce47fd440f594572cd8317 219 Pfam PF02508 Rnf-Nqr subunit, membrane protein 12 196 5.0E-55 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_1724 ac3876e835ce47fd440f594572cd8317 219 PIRSF PIRSF006102 7 215 1.4E-61 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_2523 13aa44512d53a7967d4e6098159f1a1f 368 Pfam PF07695 7TM diverse intracellular signalling 222 354 4.8E-7 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 Spica_0567 383a15a84e204c0196c622b97213d91d 519 Gene3D G3DSA:1.25.40.10 422 518 1.8E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_0090 aad6ef8b82a154182fb869fc47b7505b 447 Gene3D G3DSA:3.40.190.10 35 436 1.1E-28 T 13-10-2018 Spica_0090 aad6ef8b82a154182fb869fc47b7505b 447 SUPERFAMILY SSF53850 50 441 5.69E-24 T 13-10-2018 Spica_2801 0b2f721d032edcc3498b9c0532955fb4 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 279 2.4E-25 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0336 fadb920f812ab7302d867d4d006c7eec 166 Pfam PF03748 Flagellar basal body-associated protein FliL 87 164 2.6E-5 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 Spica_0550 f28f0aac77509d93c331f7f8436f5b38 176 Pfam PF02417 Chromate transporter 5 161 3.5E-26 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 Spica_1398 0f33940326f2040518b5bc876ab6c201 151 Pfam PF03692 Putative zinc- or iron-chelating domain 18 121 1.2E-9 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Spica_2300 a025d060f1174cc8ef592834ea83bdc3 418 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 193 416 4.1E-7 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Spica_0742 2404ba9ee98a1cd6118aed96abf48c78 506 SUPERFAMILY SSF53474 199 340 6.2E-6 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_0742 2404ba9ee98a1cd6118aed96abf48c78 506 Gene3D G3DSA:3.40.50.1820 159 359 2.1E-5 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Spica_2219 dff72862313e12ba3488257dac855fbf 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 306 8.7E-43 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0558 6396ee0a35fdd7f53822e77ddfb09913 255 Pfam PF06541 Putative ABC-transporter type IV 14 168 4.5E-39 T 13-10-2018 IPR010540 Putative ABC-transporter type IV CmpB/TMEM229 Spica_1541 adb458a1a05730b7319db1ae4c1d901f 355 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 29 215 5.4E-8 T 13-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 Spica_1541 adb458a1a05730b7319db1ae4c1d901f 355 SUPERFAMILY SSF56300 29 221 6.96E-14 T 13-10-2018 Spica_2158 c8fabf68f09e139742ff2b0bc841eb79 63 Pfam PF14070 Putative motility protein 3 61 8.0E-16 T 13-10-2018 IPR025906 Putative motility protein Spica_1996 833a67f51b12472ad3bc7107185827b4 177 Gene3D G3DSA:3.30.450.20 31 162 1.6E-9 T 13-10-2018 Spica_1034 86c2c35ee4b4234c304ec050d7b7f321 938 SUPERFAMILY SSF51126 624 776 1.88E-9 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Spica_2721 91d7e58841ff375ff1c1d2580eee2c86 139 Gene3D G3DSA:3.10.530.10 76 136 2.8E-13 T 13-10-2018 IPR036593 CPE0013-like superfamily Spica_2721 91d7e58841ff375ff1c1d2580eee2c86 139 SUPERFAMILY SSF160148 83 138 1.44E-14 T 13-10-2018 IPR036593 CPE0013-like superfamily Spica_2721 91d7e58841ff375ff1c1d2580eee2c86 139 Pfam PF07892 Protein of unknown function (DUF1667) 84 136 1.8E-14 T 13-10-2018 IPR012460 Protein of unknown function DUF1667 Spica_2721 91d7e58841ff375ff1c1d2580eee2c86 139 Pfam PF07892 Protein of unknown function (DUF1667) 33 56 5.1E-5 T 13-10-2018 IPR012460 Protein of unknown function DUF1667 Spica_0284 bdeb477d3befa1ba1670d83fdc921510 346 Pfam PF10974 Protein of unknown function (DUF2804) 16 345 7.3E-111 T 13-10-2018 IPR021243 Protein of unknown function DUF2804 Spica_2656 7167e07c52630b3572f10887419b8ee0 269 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 251 2.0E-20 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0317 528455bb3f8bd7b9284398c10250f1b4 154 Gene3D G3DSA:1.20.5.340 47 142 3.6E-6 T 13-10-2018 Spica_0133 04c1b05940e7e85e1894ca03c5933035 251 Gene3D G3DSA:1.20.1540.10 87 245 2.2E-25 T 13-10-2018 IPR035952 Rhomboid-like superfamily Spica_0133 04c1b05940e7e85e1894ca03c5933035 251 SUPERFAMILY SSF144091 12 244 3.53E-36 T 13-10-2018 Spica_0133 04c1b05940e7e85e1894ca03c5933035 251 Pfam PF01694 Rhomboid family 88 236 7.3E-33 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Spica_1549 aece02c4458e11a678b138dd29d6a40d 267 Gene3D G3DSA:3.10.520.10 6 267 1.5E-62 T 13-10-2018 Spica_1549 aece02c4458e11a678b138dd29d6a40d 267 SUPERFAMILY SSF143631 47 250 3.79E-55 T 13-10-2018 IPR003374 ApbE-like superfamily Spica_1275 fd34844f2d35c00dc495387f88e46f61 162 Pfam PF02681 Divergent PAP2 family 17 155 6.2E-42 T 13-10-2018 IPR003832 Protein of unknown function DUF212 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 PRINTS PR00845 Glycosyl hydrolase family 52 signature 90 117 2.7E-28 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 PRINTS PR00845 Glycosyl hydrolase family 52 signature 259 279 2.7E-28 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 PRINTS PR00845 Glycosyl hydrolase family 52 signature 23 50 2.7E-28 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 PRINTS PR00845 Glycosyl hydrolase family 52 signature 137 157 2.7E-28 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 PRINTS PR00845 Glycosyl hydrolase family 52 signature 333 362 2.7E-28 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0309 1d5116c7d54aaf7965a1fdec09e4254e 698 Pfam PF03512 Glycosyl hydrolase family 52 24 427 2.0E-161 T 13-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 Spica_0869 9de574a78b2dd5a1603c508b7b8bbfe3 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 104 223 3.5E-22 T 13-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein Spica_0585 a194b709d2812af93797e9f56f277d04 119 SUPERFAMILY SSF141371 9 91 3.73E-6 T 13-10-2018 Spica_2317 d5415dd2bec7effa2b3a1f944bf44b36 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 325 8.5E-26 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_0836 69a61c37f150eecc38e1b60f4b79bec9 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 281 3.2E-46 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_2288 14804c7862febb088ea3e75ce994a3bd 118 SUPERFAMILY SSF75138 1 108 1.96E-16 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_0783 e4a73e598cb0beb26294b665680cf950 111 Pfam PF04327 Cysteine protease Prp 1 102 6.6E-17 T 13-10-2018 IPR007422 Cysteine protease Prp Spica_0783 e4a73e598cb0beb26294b665680cf950 111 Gene3D G3DSA:3.30.70.1490 3 109 7.3E-16 T 13-10-2018 IPR036764 Cysteine protease Prp superfamily Spica_0783 e4a73e598cb0beb26294b665680cf950 111 SUPERFAMILY SSF118010 1 106 2.62E-16 T 13-10-2018 IPR036764 Cysteine protease Prp superfamily Spica_2682 3bf9d9692fc79daf088b4a529bb438aa 224 Pfam PF06226 Protein of unknown function (DUF1007) 16 224 1.7E-45 T 13-10-2018 IPR010412 Protein of unknown function DUF1007 Spica_1723 b47fc944bd8676a22f1050d92b5ab82f 197 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 193 6.8E-53 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_1723 b47fc944bd8676a22f1050d92b5ab82f 197 PIRSF PIRSF006102 5 197 3.3E-57 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 Spica_2483 96d70c6ba3432e6b122aba37a4e25dbf 511 Pfam PF17239 Family of unknown function (DUF5312) 3 498 1.5E-14 T 13-10-2018 IPR035196 Protein of unknown function DUF5312 Spica_0038 355dab647ed6bbee2ceacf03f8a8ec51 456 Pfam PF01554 MatE 19 183 2.4E-28 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_0038 355dab647ed6bbee2ceacf03f8a8ec51 456 Pfam PF01554 MatE 254 410 1.5E-10 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Spica_2124 fc8a6631c1c76ee5e295c32399baad10 172 Pfam PF00872 Transposase, Mutator family 17 132 2.6E-32 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Spica_1606 d3f1d9a61ba0148479e55b060ba595a5 153 Pfam PF04519 Polymer-forming cytoskeletal 27 123 9.9E-21 T 13-10-2018 IPR007607 Bactofilin A/B Spica_2312 6a2015afcad7bd008b1b43fabffb9d3e 260 Pfam PF01925 Sulfite exporter TauE/SafE 36 253 3.0E-17 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Spica_1087 e54a723e8a3fc9e95eac4842713d01a3 239 Pfam PF10719 Late competence development protein ComFB 4 90 3.9E-20 T 13-10-2018 IPR019657 Late competence development protein ComFB Spica_1125 40b545a6f90fb8c3fba5320575b76921 656 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 382 641 1.3E-50 T 13-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 Spica_1125 40b545a6f90fb8c3fba5320575b76921 656 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 107 2.8E-17 T 13-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 Spica_2725 1dec6f3ba36977f9162e893f921a9953 305 SUPERFAMILY SSF56281 4 303 1.39E-39 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2725 1dec6f3ba36977f9162e893f921a9953 305 Pfam PF00753 Metallo-beta-lactamase superfamily 25 90 6.6E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase Spica_2725 1dec6f3ba36977f9162e893f921a9953 305 Gene3D G3DSA:3.60.15.10 6 305 7.5E-41 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0847 a2c6a3cc39951ac48ac6e165f0f78135 75 Pfam PF11381 Protein of unknown function (DUF3185) 3 66 1.1E-20 T 13-10-2018 IPR021521 Protein of unknown function DUF3185 Spica_1462 8462b4c7c468f1dffd54ee72d5ece932 325 Gene3D G3DSA:2.115.10.20 159 320 7.2E-7 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_1462 8462b4c7c468f1dffd54ee72d5ece932 325 SUPERFAMILY SSF75005 85 313 2.78E-14 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_0859 898217473a5677876aa13cb93c3a82bb 303 Pfam PF14257 Domain of unknown function (DUF4349) 44 283 2.8E-71 T 13-10-2018 IPR025645 Domain of unknown function DUF4349 Spica_2311 62c93df929cf2ae817b01d9a6a37316e 526 Pfam PF13559 Domain of unknown function (DUF4129) 449 516 5.9E-9 T 13-10-2018 IPR025403 Domain of unknown function DUF4129 Spica_0678 d4b0bebdcfb3675e9553a382af4c601e 243 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 82 205 2.1E-11 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 Spica_2184 7be835ed713951989059ffc3c2216885 324 SUPERFAMILY SSF56954 39 257 5.36E-8 T 13-10-2018 Spica_1592 845cbd2b6f42e8567147ca97e048876e 327 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 12 231 8.2E-50 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Spica_0318 3c7ff9d6069596999a9d4c741b849b35 444 SUPERFAMILY SSF48452 259 435 1.19E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Spica_2558 304a37a864e0c1104166e1e844bd86c2 412 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 97 292 1.1E-13 T 13-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 Spica_0242 10e0ecbea9aa9b012e64562cbeddc80f 966 Pfam PF03961 Flagellar Assembly Protein A 322 509 1.1E-18 T 13-10-2018 IPR005646 Flagellar assembly protein A Spica_0242 10e0ecbea9aa9b012e64562cbeddc80f 966 Pfam PF03961 Flagellar Assembly Protein A 526 956 5.8E-86 T 13-10-2018 IPR005646 Flagellar assembly protein A Spica_1255 da58c6d9aec9fa437b6262c30bd9efcc 554 Pfam PF14052 Capsule assembly protein Wzi 183 531 6.4E-9 T 13-10-2018 IPR026950 Capsule assembly protein Wzi Spica_0691 56c3a76395898b3831cadeaf9b7f31fa 265 Pfam PF02361 Cobalt transport protein 34 220 2.9E-7 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component Spica_1157 3b2322b61447d45aead26352170f5e73 259 Pfam PF13228 Domain of unknown function (DUF4037) 124 208 1.1E-4 T 13-10-2018 IPR025117 Domain of unknown function DUF4037 Spica_0837 286e785a0ce39aa64d1ce650f424fa42 351 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 315 3.5E-45 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Spica_2430 3dce63c9efec1c16f04b1ac42e5aff78 409 Gene3D G3DSA:3.10.20.310 27 102 4.2E-7 T 13-10-2018 Spica_1217 0c0151fdb67bd94c7c8783a18cba72b4 617 Pfam PF01973 Protein of unknown function DUF115 203 371 6.5E-35 T 13-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Spica_2750 a8d09ca6c9bcf7f85a4f2ab93a550893 463 Pfam PF02470 MlaD protein 38 111 1.5E-9 T 13-10-2018 IPR003399 Mce/MlaD Spica_0759 82c9b057ae3126d2d604808398272576 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 278 2.2E-42 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085