locus-tag	class	description
TDE_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TDE_0002	COG0187	DNA topoisomerase II activity
TDE_0006	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TDE_0010	COG0494	nUDIX hydrolase
TDE_0011	COG0450	alkyl hydroperoxide reductase
TDE_0012	COG1966	Carbon starvation protein
TDE_0013	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TDE_0016	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TDE_0017	COG1363	Peptidase, m42
TDE_0019	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TDE_0020	COG0423	glycine-tRNA ligase activity
TDE_0024	COG1472	Belongs to the glycosyl hydrolase 3 family
TDE_0029	COG1132	(ABC) transporter
TDE_0038	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TDE_0039	COG2801	Transposase and inactivated derivatives
TDE_0040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TDE_0042	COG0280	phosphate acetyltransferase
TDE_0043	COG0457	Tetratricopeptide repeat
TDE_0044	COG0488	(ABC) transporter
TDE_0047	COG1228	amidohydrolase
TDE_0052	COG1987	bacterial-type flagellum assembly
TDE_0053	COG1684	flagellar biosynthetic protein fliR
TDE_0054	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TDE_0055	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TDE_0057	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TDE_0064	COG0205	6-phosphofructokinase activity
TDE_0067	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TDE_0068	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TDE_0069	COG1509	lysine 2,3-aminomutase activity
TDE_0070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TDE_0071	COG0826	peptidase U32
TDE_0072	COG0840	transmembrane signaling receptor activity
TDE_0073	COG0196	riboflavin kinase activity
TDE_0074	COG0531	amino acid
TDE_0075	COG1063	alcohol dehydrogenase
TDE_0076	COG1830	Aldolase
TDE_0080	COG1012	belongs to the aldehyde dehydrogenase family
TDE_0083	COG1160	GTP binding
TDE_0084	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TDE_0085	COG1074	ATP-dependent DNA helicase activity
TDE_0086	COG2887	Belongs to the helicase family. UvrD subfamily
TDE_0087	COG0569	domain protein
TDE_0088	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TDE_0089	COG1305	Transglutaminase-like
TDE_0092	COG0215	cysteine-tRNA ligase activity
TDE_0093	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TDE_0100	COG0823	Involved in the tonB-independent uptake of proteins
TDE_0100	COG1506	peptidase
TDE_0100	COG4946	Tricorn protease homolog
TDE_0103	COG1104	cysteine desulfurase activity
TDE_0104	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TDE_0105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TDE_0109	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TDE_0110	COG0739	heme binding
TDE_0112	COG1728	Protein conserved in bacteria
TDE_0113	COG1774	PSP1 C-terminal conserved region
TDE_0116	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
TDE_0125	COG0745	RESPONSE REGULATOR receiver
TDE_0125	COG3706	GGDEF domain
TDE_0128	COG5002	protein histidine kinase activity
TDE_0128	COG5001	Diguanylate cyclase
TDE_0129	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TDE_0129	COG0540	Belongs to the ATCase OTCase family
TDE_0130	COG1823	symporter activity
TDE_0135	COG0446	pyridine nucleotide-disulphide oxidoreductase
TDE_0137	COG1070	Carbohydrate kinase
TDE_0138	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TDE_0146	COG1473	amidohydrolase
TDE_0148	COG4585	Histidine kinase
TDE_0150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TDE_0153	COG0446	pyridine nucleotide-disulphide oxidoreductase
TDE_0157	COG0800	Aldolase
TDE_0163	COG0716	FMN binding
TDE_0167	COG1131	(ABC) transporter
TDE_0169	COG0840	transmembrane signaling receptor activity
TDE_0169	COG3290	protein histidine kinase activity
TDE_0170	COG0420	3'-5' exonuclease activity
TDE_0171	COG0419	ATPase involved in DNA repair
TDE_0172	COG1968	undecaprenyl-diphosphatase activity
TDE_0173	COG1674	ftsk spoiiie
TDE_0174	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TDE_0175	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TDE_0178	COG0840	transmembrane signaling receptor activity
TDE_0181	COG0840	transmembrane signaling receptor activity
TDE_0183	COG4208	sulfate ABC transporter
TDE_0188	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TDE_0189	COG0730	response to heat
TDE_0200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TDE_0204	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TDE_0207	COG2610	gluconate transmembrane transporter activity
TDE_0208	COG1929	Belongs to the glycerate kinase type-1 family
TDE_0209	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TDE_0211	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TDE_0230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TDE_0231	COG0592	DNA-directed DNA polymerase activity
TDE_0232	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TDE_0233	COG3177	Filamentation induced by cAMP protein fic
TDE_0237	COG1418	mRNA catabolic process
TDE_0243	COG1129	ABC transporter
TDE_0244	COG1132	(ABC) transporter
TDE_0245	COG1132	(ABC) transporter
TDE_0246	COG1309	transcriptional regulator
TDE_0248	COG3189	MarR family transcriptional regulator
TDE_0250	COG0733	neurotransmitter:sodium symporter activity
TDE_0255	COG1129	ABC transporter
TDE_0258	COG2226	methyltransferase
TDE_0259	COG1846	Transcriptional regulator
TDE_0267	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TDE_0273	COG1132	(ABC) transporter
TDE_0279	COG0596	Alpha beta hydrolase
TDE_0282	COG1129	ABC transporter
TDE_0285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TDE_0286	COG1132	(ABC) transporter
TDE_0292	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TDE_0294	COG0569	domain protein
TDE_0295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TDE_0299	COG0494	nUDIX hydrolase
TDE_0300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TDE_0305	COG0012	GTP binding
TDE_0306	COG0616	signal peptide processing
TDE_0311	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TDE_0312	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TDE_0313	COG0569	domain protein
TDE_0316	COG1132	(ABC) transporter
TDE_0319	COG0714	Associated with various cellular activities
TDE_0320	COG4536	flavin adenine dinucleotide binding
TDE_0321	COG4536	flavin adenine dinucleotide binding
TDE_0326	COG0514	ATP-dependent DNA helicase (RecQ)
TDE_0328	COG1518	maintenance of DNA repeat elements
TDE_0329	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TDE_0332	COG1309	transcriptional regulator
TDE_0335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TDE_0336	COG0628	permease
TDE_0337	COG0363	glucosamine-6-phosphate deaminase activity
TDE_0339	COG1309	transcriptional regulator
TDE_0340	COG3588	fructose-bisphosphate aldolase
TDE_0341	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TDE_0342	COG0728	peptidoglycan biosynthetic process
TDE_0345	COG0840	transmembrane signaling receptor activity
TDE_0347	COG0840	transmembrane signaling receptor activity
TDE_0348	COG1309	transcriptional regulator
TDE_0349	COG0574	Belongs to the PEP-utilizing enzyme family
TDE_0349	COG3848	Pyruvate phosphate dikinase
TDE_0350	COG0534	Mate efflux family protein
TDE_0351	COG0039	L-malate dehydrogenase activity
TDE_0352	COG0698	ribose 5-phosphate isomerase
TDE_0354	COG2249	NAD(P)H dehydrogenase (quinone) activity
TDE_0359	COG1132	(ABC) transporter
TDE_0360	COG1132	(ABC) transporter
TDE_0361	COG0786	glutamate:sodium symporter activity
TDE_0366	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TDE_0370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TDE_0372	COG3271	cysteine-type peptidase activity
TDE_0372	COG2274	protein secretion by the type I secretion system
TDE_0373	COG1132	(ABC) transporter
TDE_0374	COG0438	transferase activity, transferring glycosyl groups
TDE_0385	COG4133	protoheme IX ABC transporter activity
TDE_0386	COG1840	ABC-type Fe3 transport system, periplasmic component
TDE_0389	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
TDE_0392	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
TDE_0395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_0396	COG0444	Belongs to the ABC transporter superfamily
TDE_0397	COG4608	Belongs to the ABC transporter superfamily
TDE_0398	COG0747	negative chemotaxis
TDE_0401	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TDE_0408	COG0543	2 iron, 2 sulfur cluster binding
TDE_0410	COG0501	Belongs to the peptidase M48B family
TDE_0411	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TDE_0431	COG1652	LysM domain
TDE_0431	COG2823	Periplasmic or secreted lipoprotein
TDE_0434	COG1592	Rubrerythrin
TDE_0435	COG0514	ATP-dependent DNA helicase (RecQ)
TDE_0436	COG1381	Involved in DNA repair and RecF pathway recombination
TDE_0438	COG0343	queuine tRNA-ribosyltransferase activity
TDE_0444	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TDE_0448	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TDE_0450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TDE_0451	COG2235	arginine
TDE_0455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TDE_0456	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TDE_0462	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TDE_0463	COG0813	purine-nucleoside phosphorylase activity
TDE_0470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TDE_0475	COG0577	efflux transmembrane transporter activity
TDE_0475	COG1136	(ABC) transporter
TDE_0476	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TDE_0479	COG1151	hydroxylamine reductase activity
TDE_0487	COG1131	(ABC) transporter
TDE_0492	COG0745	RESPONSE REGULATOR receiver
TDE_0494	COG3550	peptidyl-serine autophosphorylation
TDE_0496	COG1396	sequence-specific DNA binding
TDE_0505	COG3041	Addiction module toxin RelE StbE family
TDE_0535	COG1136	(ABC) transporter
TDE_0571	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TDE_0571	COG0515	serine threonine protein kinase
TDE_0575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TDE_0576	COG0154	amidase activity
TDE_0577	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TDE_0582	COG0714	Associated with various cellular activities
TDE_0583	COG3689	TIGRFAM TIGR03943 family protein
TDE_0584	COG0701	Predicted permease
TDE_0588	COG2986	histidine ammonia-lyase
TDE_0589	COG0825	malonyl-CoA metabolic process
TDE_0590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TDE_0591	COG0439	Biotin carboxylase
TDE_0597	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TDE_0598	COG1028	Short-chain dehydrogenase reductase Sdr
TDE_0601	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TDE_0602	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TDE_0606	COG1475	DNA binding
TDE_0607	COG1192	Involved in chromosome partitioning
TDE_0610	COG1250	3-hydroxyacyl-CoA dehydrogenase
TDE_0614	COG2875	Belongs to the precorrin methyltransferase family
TDE_0621	COG0534	Mate efflux family protein
TDE_0625	COG1120	ATPase activity
TDE_0627	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TDE_0628	COG0443	Heat shock 70 kDa protein
TDE_0629	COG0484	heat shock protein binding
TDE_0634	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TDE_0636	COG4608	Belongs to the ABC transporter superfamily
TDE_0637	COG0444	Belongs to the ABC transporter superfamily
TDE_0638	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_0639	COG0601	transmembrane transport
TDE_0641	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TDE_0643	COG0193	aminoacyl-tRNA hydrolase activity
TDE_0644	COG1137	ATPase activity
TDE_0648	COG2201	protein-glutamate methylesterase activity
TDE_0654	COG1473	amidohydrolase
TDE_0656	COG5002	protein histidine kinase activity
TDE_0657	COG1136	(ABC) transporter
TDE_0660	COG2378	regulation of single-species biofilm formation
TDE_0662	COG4115	mRNA cleavage
TDE_0664	COG2885	chlorophyll binding
TDE_0665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TDE_0665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TDE_0665	COG1013	pyruvate-flavodoxin oxidoreductase activity
TDE_0665	COG0674	pyruvate-flavodoxin oxidoreductase activity
TDE_0666	COG0396	ATPase activity
TDE_0667	COG0719	Fe-S assembly protein
TDE_0670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TDE_0677	COG0425	Belongs to the sulfur carrier protein TusA family
TDE_0680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TDE_0681	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TDE_0682	COG1862	Preprotein translocase
TDE_0685	COG0300	oxidoreductase activity
TDE_0686	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TDE_0687	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TDE_0689	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
TDE_0690	COG0482	sulfurtransferase activity
TDE_0693	COG0351	phosphomethylpyrimidine kinase
TDE_0694	COG1131	(ABC) transporter
TDE_0702	COG1131	(ABC) transporter
TDE_0705	COG0330	HflC and HflK could
TDE_0714	COG1086	Polysaccharide biosynthesis protein
TDE_0716	COG1266	CAAX protease self-immunity
TDE_0720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TDE_0725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TDE_0732	COG1012	belongs to the aldehyde dehydrogenase family
TDE_0737	COG4115	mRNA cleavage
TDE_0744	COG3118	belongs to the thioredoxin family
TDE_0746	COG1120	ATPase activity
TDE_0747	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TDE_0750	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TDE_0750	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TDE_0751	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TDE_0752	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TDE_0755	COG1757	Na H antiporter
TDE_0756	COG1120	ATPase activity
TDE_0757	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TDE_0765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TDE_0766	COG0051	transcription antitermination factor activity, RNA binding
TDE_0767	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TDE_0768	COG0088	Forms part of the polypeptide exit tunnel
TDE_0769	COG0089	rRNA binding
TDE_0770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TDE_0771	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TDE_0772	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TDE_0773	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TDE_0774	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TDE_0775	COG0255	Belongs to the universal ribosomal protein uL29 family
TDE_0776	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TDE_0777	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TDE_0778	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TDE_0779	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TDE_0780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TDE_0781	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TDE_0782	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TDE_0783	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TDE_0784	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TDE_0785	COG1841	ribosomal large subunit assembly
TDE_0786	COG0200	Binds to the 23S rRNA
TDE_0788	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TDE_0789	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TDE_0790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TDE_0791	COG0202	RNA polymerase activity
TDE_0792	COG0203	ribosomal protein L17
TDE_0797	COG1254	Belongs to the acylphosphatase family
TDE_0801	COG1959	2 iron, 2 sulfur cluster binding
TDE_0802	COG2910	NAD(P)H-binding
TDE_0804	COG1690	Belongs to the RtcB family
TDE_0813	COG1132	(ABC) transporter
TDE_0815	COG1288	antiporter activity
TDE_0816	COG1473	amidohydrolase
TDE_0818	COG1132	(ABC) transporter
TDE_0819	COG1132	(ABC) transporter
TDE_0823	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TDE_0824	COG2340	Cysteine-rich secretory protein family
TDE_0825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TDE_0826	COG3422	double-strand break repair
TDE_0828	COG0445	tRNA wobble uridine modification
TDE_0829	COG1362	aminopeptidase activity
TDE_0833	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TDE_0834	COG4657	Part of a membrane complex involved in electron transport
TDE_0835	COG4660	Part of a membrane complex involved in electron transport
TDE_0836	COG4659	FMN binding
TDE_0837	COG4658	electron transport chain
TDE_0838	COG4656	Part of a membrane complex involved in electron transport
TDE_0841	COG2304	oxidoreductase activity
TDE_0844	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TDE_0844	COG0574	Belongs to the PEP-utilizing enzyme family
TDE_0846	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TDE_0852	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TDE_0853	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TDE_0854	COG2137	regulation of response to DNA damage stimulus
TDE_0855	COG2197	response regulator
TDE_0860	COG1187	pseudouridine synthase activity
TDE_0861	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TDE_0863	COG1285	pathogenesis
TDE_0864	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TDE_0870	COG0737	Belongs to the 5'-nucleotidase family
TDE_0872	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TDE_0873	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TDE_0874	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TDE_0881	COG0228	four-way junction DNA binding
TDE_0882	COG1837	Belongs to the UPF0109 family
TDE_0883	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TDE_0884	COG0336	Belongs to the RNA methyltransferase TrmD family
TDE_0885	COG0335	large ribosomal subunit rRNA binding
TDE_0891	COG2378	regulation of single-species biofilm formation
TDE_0893	COG4555	ABC transporter
TDE_0895	COG2207	Transcriptional regulator
TDE_0896	COG1132	(ABC) transporter
TDE_0897	COG1132	(ABC) transporter
TDE_0900	COG1129	ABC transporter
TDE_0903	COG0210	DNA helicase
TDE_0906	COG1129	ABC transporter
TDE_0908	COG1132	(ABC) transporter
TDE_0916	COG1132	(ABC) transporter
TDE_0921	COG1132	(ABC) transporter
TDE_0922	COG1132	(ABC) transporter
TDE_0923	COG1132	(ABC) transporter
TDE_0925	COG2195	Cleaves the N-terminal amino acid of tripeptides
TDE_0928	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TDE_0929	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TDE_0930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TDE_0931	COG0534	Mate efflux family protein
TDE_0933	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TDE_0934	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TDE_0937	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TDE_0938	COG0116	Belongs to the methyltransferase superfamily
TDE_0939	COG3735	TraB family
TDE_0941	COG0791	NLP P60 protein
TDE_0942	COG0318	PFAM AMP-dependent synthetase and ligase
TDE_0947	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TDE_0949	COG0148	phosphopyruvate hydratase activity
TDE_0951	COG1744	ABC transporter substrate-binding protein PnrA-like
TDE_0952	COG3845	ABC transporter
TDE_0953	COG4603	Belongs to the binding-protein-dependent transport system permease family
TDE_0954	COG1079	Belongs to the binding-protein-dependent transport system permease family
TDE_0955	COG1704	LemA family
TDE_0956	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TDE_0957	COG0584	glycerophosphoryl diester phosphodiesterase
TDE_0958	COG1752	Esterase of the alpha-beta hydrolase superfamily
TDE_0959	COG5341	Protein conserved in bacteria
TDE_0960	COG2089	acid synthase
TDE_0961	COG0484	heat shock protein binding
TDE_0963	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TDE_0965	COG1692	metallophosphoesterase
TDE_0966	COG0084	hydrolase, TatD family'
TDE_0968	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TDE_0971	COG0018	arginyl-trna synthetase
TDE_0972	COG1040	competence protein
TDE_0973	COG2003	Belongs to the UPF0758 family
TDE_0977	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TDE_0979	COG1686	Belongs to the peptidase S11 family
TDE_0980	COG0017	Asparaginyl-tRNA synthetase
TDE_0984	COG4239	(ABC) transporter, permease
TDE_0986	COG0444	Belongs to the ABC transporter superfamily
TDE_0987	COG4608	Belongs to the ABC transporter superfamily
TDE_0988	COG0747	negative chemotaxis
TDE_0991	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TDE_0992	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TDE_0999	COG2116	formate transmembrane transporter activity
TDE_1000	COG2084	Dehydrogenase
TDE_1006	COG4786	Flagellar basal body rod
TDE_1008	COG3951	Flagellar rod assembly protein muramidase FlgJ
TDE_1010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TDE_1012	COG2183	response to ionizing radiation
TDE_1013	COG2703	oxygen carrier activity
TDE_1023	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TDE_1025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TDE_1026	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TDE_1027	COG0571	ribonuclease III activity
TDE_1029	COG0071	Belongs to the small heat shock protein (HSP20) family
TDE_1033	COG0617	tRNA 3'-terminal CCA addition
TDE_1034	COG0598	Magnesium transport protein CorA
TDE_1039	COG0196	riboflavin kinase activity
TDE_1040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TDE_1041	COG1185	polyribonucleotide nucleotidyltransferase activity
TDE_1042	COG0756	dUTP diphosphatase activity
TDE_1045	COG2832	Protein of unknown function (DUF454)
TDE_1047	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TDE_1048	COG0049	tRNA binding
TDE_1049	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TDE_1054	COG0840	transmembrane signaling receptor activity
TDE_1055	COG0534	Mate efflux family protein
TDE_1063	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TDE_1063	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TDE_1067	COG4608	Belongs to the ABC transporter superfamily
TDE_1068	COG0444	Belongs to the ABC transporter superfamily
TDE_1069	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_1070	COG0601	transmembrane transport
TDE_1074	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_1075	COG0444	Belongs to the ABC transporter superfamily
TDE_1076	COG4608	Belongs to the ABC transporter superfamily
TDE_1078	COG0426	domain, Protein
TDE_1078	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TDE_1079	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TDE_1080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TDE_1083	COG0564	pseudouridine synthase activity
TDE_1085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TDE_1086	COG1561	YicC-like family, N-terminal region
TDE_1087	COG1102	Psort location Cytoplasmic, score
TDE_1088	COG3706	GGDEF domain
TDE_1090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TDE_1093	COG3330	Domain of unknown function (DUF4912)
TDE_1095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TDE_1096	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TDE_1104	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TDE_1105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TDE_1106	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TDE_1108	COG0779	Required for maturation of 30S ribosomal subunits
TDE_1112	COG0563	adenylate kinase activity
TDE_1118	COG3033	Beta-eliminating lyase
TDE_1122	COG1366	Belongs to the anti-sigma-factor antagonist family
TDE_1130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TDE_1132	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TDE_1162	COG1475	DNA binding
TDE_1173	COG4974	Belongs to the 'phage' integrase family
TDE_1175	COG0459	protein refolding
TDE_1176	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TDE_1178	COG1120	ATPase activity
TDE_1179	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TDE_1183	COG1120	ATPase activity
TDE_1188	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
TDE_1195	COG1505	serine-type exopeptidase activity
TDE_1197	COG2001	Belongs to the MraZ family
TDE_1198	COG0275	rRNA processing
TDE_1200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TDE_1201	COG0772	Belongs to the SEDS family
TDE_1204	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TDE_1205	COG4974	Belongs to the 'phage' integrase family
TDE_1207	COG0758	DNA mediated transformation
TDE_1208	COG0551	DNA topoisomerase type I activity
TDE_1208	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TDE_1209	COG4974	Belongs to the 'phage' integrase family
TDE_1210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TDE_1211	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TDE_1214	COG1677	Flagellar hook-basal body complex protein FliE
TDE_1215	COG1766	The M ring may be actively involved in energy transduction
TDE_1217	COG1317	bacterial-type flagellum organization
TDE_1218	COG1157	protein secretion by the type III secretion system
TDE_1223	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TDE_1224	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TDE_1225	COG1121	(ABC) transporter
TDE_1226	COG0803	Belongs to the bacterial solute-binding protein 9 family
TDE_1229	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TDE_1236	COG0149	triose-phosphate isomerase activity
TDE_1240	COG1702	phosphate starvation-inducible protein PhoH
TDE_1241	COG1480	7TM receptor with intracellular HD hydrolase
TDE_1242	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TDE_1254	COG1193	negative regulation of DNA recombination
TDE_1259	COG1115	amino acid carrier protein
TDE_1260	COG4750	Nucleotidyl transferase
TDE_1264	COG3118	belongs to the thioredoxin family
TDE_1265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TDE_1266	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TDE_1271	COG4608	Belongs to the ABC transporter superfamily
TDE_1272	COG0444	Belongs to the ABC transporter superfamily
TDE_1274	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_1275	COG0601	transmembrane transport
TDE_1278	COG4475	Protein of unknown function (DUF436)
TDE_1279	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TDE_1284	COG0840	transmembrane signaling receptor activity
TDE_1285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TDE_1292	COG0312	modulator of DNA gyrase
TDE_1293	COG0312	modulator of DNA gyrase
TDE_1294	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TDE_1297	COG1388	LysM domain
TDE_1297	COG0791	NLP P60 protein
TDE_1301	COG0497	DNA recombination
TDE_1308	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TDE_1309	COG0312	modulator of DNA gyrase
TDE_1311	COG4988	ABC transporter
TDE_1312	COG0433	COG0433 Predicted ATPase
TDE_1314	COG0768	penicillin binding
TDE_1315	COG2604	Protein of unknown function DUF115
TDE_1321	COG1739	Uncharacterized protein family UPF0029
TDE_1330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TDE_1332	COG0330	HflC and HflK could
TDE_1333	COG0330	HflC and HflK could
TDE_1338	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TDE_1339	COG2088	sporulation resulting in formation of a cellular spore
TDE_1340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TDE_1341	COG0037	tRNA processing
TDE_1342	COG0457	Tetratricopeptide repeat
TDE_1343	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TDE_1345	COG0358	DNA primase activity
TDE_1346	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TDE_1349	COG1077	Cell shape determining protein MreB Mrl
TDE_1352	COG0768	penicillin binding
TDE_1353	COG0772	Belongs to the SEDS family
TDE_1360	COG2252	PERMEase
TDE_1364	COG0525	valine-tRNA ligase activity
TDE_1366	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TDE_1367	COG0346	lactoylglutathione lyase activity
TDE_1369	COG0556	nucleotide-excision repair
TDE_1370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TDE_1370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TDE_1371	COG0557	exoribonuclease II activity
TDE_1375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TDE_1381	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TDE_1382	COG0640	Transcriptional regulator
TDE_1384	COG2217	Heavy metal translocating P-type atpase
TDE_1387	COG0564	pseudouridine synthase activity
TDE_1390	COG4656	Part of a membrane complex involved in electron transport
TDE_1391	COG4658	electron transport chain
TDE_1397	COG0455	bacterial-type flagellum organization
TDE_1399	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TDE_1400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TDE_1400	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TDE_1403	COG0488	(ABC) transporter
TDE_1405	COG0047	phosphoribosylformylglycinamidine synthase activity
TDE_1407	COG1078	dGTPase activity
TDE_1414	COG0028	Belongs to the TPP enzyme family
TDE_1414	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TDE_1429	COG0463	Glycosyl transferase, family 2
TDE_1430	COG0463	Glycosyl transferase, family 2
TDE_1431	COG0438	transferase activity, transferring glycosyl groups
TDE_1433	COG1216	Glycosyl transferase, family 2
TDE_1435	COG1215	transferase activity, transferring glycosyl groups
TDE_1435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TDE_1436	COG0706	membrane insertase activity
TDE_1438	COG0297	glycogen (starch) synthase activity
TDE_1439	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TDE_1442	COG0124	histidyl-tRNA synthetase
TDE_1444	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TDE_1447	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TDE_1448	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TDE_1449	COG1162	GTPase activity
TDE_1450	COG1193	negative regulation of DNA recombination
TDE_1454	COG2190	(PTS) system
TDE_1454	COG2211	Major facilitator Superfamily
TDE_1464	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TDE_1466	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TDE_1467	COG2770	Histidine kinase
TDE_1467	COG3437	response regulator, receiver
TDE_1469	COG0802	atpase or kinase
TDE_1472	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TDE_1472	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TDE_1475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TDE_1477	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TDE_1487	COG0217	transcriptional regulatory protein
TDE_1488	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TDE_1491	COG0643	Histidine kinase
TDE_1491	COG2198	Histidine kinase
TDE_1492	COG0835	chemotaxis
TDE_1494	COG2201	protein-glutamate methylesterase activity
TDE_1496	COG1196	nuclear chromosome segregation
TDE_1498	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TDE_1499	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TDE_1501	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TDE_1501	COG0574	Belongs to the PEP-utilizing enzyme family
TDE_1503	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TDE_1504	COG0254	rRNA binding
TDE_1506	COG1760	l-serine dehydratase
TDE_1507	COG1760	l-serine dehydratase
TDE_1509	COG1136	(ABC) transporter
TDE_1510	COG0672	)-iron permease
TDE_1511	COG3470	protein probably involved in high-affinity Fe2 transport
TDE_1515	COG1136	(ABC) transporter
TDE_1515	COG0577	efflux transmembrane transporter activity
TDE_1516	COG1136	(ABC) transporter
TDE_1520	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TDE_1522	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
TDE_1523	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
TDE_1535	COG1692	metallophosphoesterase
TDE_1537	COG0142	geranyltranstransferase activity
TDE_1538	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TDE_1540	COG0727	PFAM Uncharacterised protein family (UPF0153)
TDE_1543	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TDE_1547	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TDE_1548	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TDE_1549	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TDE_1550	COG0205	6-phosphofructokinase activity
TDE_1551	COG0095	Lipoate-protein ligase
TDE_1575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TDE_1576	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TDE_1580	COG2982	Protein involved in outer membrane biogenesis
TDE_1581	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
TDE_1582	COG0297	glycogen (starch) synthase activity
TDE_1587	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TDE_1589	COG0835	chemotaxis
TDE_1591	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TDE_1592	COG0488	(ABC) transporter
TDE_1594	COG0493	'glutamate synthase
TDE_1594	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TDE_1595	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TDE_1598	COG1129	ABC transporter
TDE_1599	COG1132	(ABC) transporter
TDE_1600	COG1132	(ABC) transporter
TDE_1601	COG1309	transcriptional regulator
TDE_1603	COG1129	ABC transporter
TDE_1608	COG2226	methyltransferase
TDE_1612	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TDE_1616	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TDE_1624	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TDE_1626	COG0509	glycine decarboxylation via glycine cleavage system
TDE_1627	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TDE_1629	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TDE_1633	COG3052	prosthetic group binding
TDE_1637	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TDE_1637	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TDE_1637	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TDE_1638	COG0237	dephospho-CoA kinase activity
TDE_1640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TDE_1641	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TDE_1644	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TDE_1645	COG0242	peptide deformylase activity
TDE_1650	COG1122	ATPase activity
TDE_1651	COG1268	BioY protein
TDE_1652	COG1132	(ABC) transporter
TDE_1657	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TDE_1658	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TDE_1659	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TDE_1662	COG0305	Participates in initiation and elongation during chromosome replication
TDE_1667	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TDE_1669	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TDE_1671	COG0544	peptidyl-prolyl cis-trans isomerase activity
TDE_1672	COG0740	serine-type endopeptidase activity
TDE_1673	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TDE_1675	COG0359	binds to the 23S rRNA
TDE_1676	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TDE_1677	COG0629	single-stranded DNA binding
TDE_1678	COG0360	Binds together with S18 to 16S ribosomal RNA
TDE_1681	COG1394	ATPase activity, coupled to movement of substances
TDE_1682	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TDE_1683	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TDE_1684	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TDE_1685	COG3706	GGDEF domain
TDE_1685	COG2203	Gaf domain
TDE_1685	COG4251	negative regulation of phosphorylation
TDE_1685	COG5001	Diguanylate cyclase
TDE_1687	COG0457	Tetratricopeptide repeat
TDE_1689	COG1131	(ABC) transporter
TDE_1697	COG0588	phosphoglycerate mutase activity
TDE_1706	COG1058	Belongs to the CinA family
TDE_1706	COG1546	Belongs to the CinA family
TDE_1708	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TDE_1709	COG0776	regulation of translation
TDE_1710	COG0268	Binds directly to 16S ribosomal RNA
TDE_1714	COG0860	N-Acetylmuramoyl-L-alanine amidase
TDE_1715	COG0126	phosphoglycerate kinase activity
TDE_1718	COG0519	Catalyzes the synthesis of GMP from XMP
TDE_1719	COG1846	Transcriptional regulator
TDE_1726	COG0617	tRNA 3'-terminal CCA addition
TDE_1730	COG3250	beta-galactosidase activity
TDE_1732	COG0484	heat shock protein binding
TDE_1733	COG0024	Methionine aminopeptidase
TDE_1734	COG0708	Exodeoxyribonuclease III
TDE_1736	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TDE_1738	COG0739	heme binding
TDE_1744	COG2059	Chromate
TDE_1745	COG0799	negative regulation of ribosome biogenesis
TDE_1747	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TDE_1748	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TDE_1749	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TDE_1751	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TDE_1753	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TDE_1754	COG2033	superoxide reductase activity
TDE_1760	COG1418	mRNA catabolic process
TDE_1763	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TDE_1784	COG3708	Transcriptional regulator
TDE_1784	COG2207	Transcriptional regulator
TDE_1851	COG1136	(ABC) transporter
TDE_1851	COG0577	efflux transmembrane transporter activity
TDE_1852	COG1136	(ABC) transporter
TDE_1863	COG0632	four-way junction helicase activity
TDE_1864	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TDE_1886	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TDE_1889	COG1114	Component of the transport system for branched-chain amino acids
TDE_1893	COG0481	GTPase activity
TDE_1895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TDE_1896	COG0138	bifunctional purine biosynthesis protein purh
TDE_1897	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TDE_1898	COG0653	protein targeting
TDE_1900	COG1725	Transcriptional regulator
TDE_1907	COG0736	holo-[acyl-carrier-protein] synthase activity
TDE_1910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TDE_1912	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TDE_1914	COG2255	four-way junction helicase activity
TDE_1915	COG1979	alcohol dehydrogenase
TDE_1916	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TDE_1917	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
TDE_1919	COG0731	radical SAM domain protein
TDE_1925	COG1047	Peptidyl-prolyl cis-trans
TDE_1927	COG0072	phenylalanine-tRNA ligase activity
TDE_1931	COG0295	cytidine deaminase activity
TDE_1943	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TDE_1950	COG1744	ABC transporter substrate-binding protein PnrA-like
TDE_1951	COG1234	tRNA 3'-trailer cleavage
TDE_1964	COG1283	sodium-dependent phosphate transmembrane transporter activity
TDE_1965	COG0475	glutathione-regulated potassium exporter activity
TDE_1968	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TDE_1969	COG2204	response regulator
TDE_1970	COG3852	Histidine kinase
TDE_1971	COG0470	DNA polymerase III
TDE_1973	COG1286	toxin biosynthetic process
TDE_1974	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TDE_1985	COG4254	PFAM FecR protein
TDE_1988	COG0823	Involved in the tonB-independent uptake of proteins
TDE_1990	COG1199	ATP-dependent helicase activity
TDE_1992	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
TDE_1992	COG2885	chlorophyll binding
TDE_1995	COG0606	chelatase, subunit chli
TDE_1998	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TDE_1999	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TDE_2001	COG1164	Oligoendopeptidase f
TDE_2005	COG1309	transcriptional regulator
TDE_2009	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TDE_2029	COG0084	hydrolase, TatD family'
TDE_2030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TDE_2033	COG2801	Transposase and inactivated derivatives
TDE_2034	COG0438	transferase activity, transferring glycosyl groups
TDE_2037	COG3869	Catalyzes the specific phosphorylation of arginine residues in
TDE_2038	COG3880	PFAM UvrB UvrC protein
TDE_2040	COG1136	(ABC) transporter
TDE_2041	COG4591	ABC-type transport system involved in lipoprotein release permease component
TDE_2043	COG0552	protein localization to endoplasmic reticulum
TDE_2049	COG4166	transmembrane transport
TDE_2052	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TDE_2063	COG1918	ferrous iron import across plasma membrane
TDE_2063	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TDE_2064	COG1918	ferrous iron import across plasma membrane
TDE_2066	COG1722	exodeoxyribonuclease VII activity
TDE_2069	COG0251	oxidation-reduction process
TDE_2074	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TDE_2078	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
TDE_2079	COG2204	response regulator
TDE_2080	COG0539	negative regulation of cytoplasmic translation
TDE_2084	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TDE_2085	COG0528	UMP kinase activity
TDE_2086	COG0484	heat shock protein binding
TDE_2087	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TDE_2088	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TDE_2089	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TDE_2090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TDE_2095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TDE_2096	COG3876	Protein conserved in bacteria
TDE_2107	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TDE_2109	COG0513	Belongs to the DEAD box helicase family
TDE_2110	COG0284	orotidine-5'-phosphate decarboxylase activity
TDE_2114	COG1131	(ABC) transporter
TDE_2123	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TDE_2132	COG1122	ATPase activity
TDE_2140	COG1770	oligopeptidase
TDE_2142	COG0840	transmembrane signaling receptor activity
TDE_2143	COG4953	penicillin-binding protein 1C
TDE_2144	COG3681	Belongs to the UPF0597 family
TDE_2149	COG1388	LysM domain
TDE_2149	COG0741	lytic transglycosylase activity
TDE_2151	COG1671	Belongs to the UPF0178 family
TDE_2152	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
TDE_2154	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TDE_2155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TDE_2156	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TDE_2158	COG1129	ABC transporter
TDE_2161	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TDE_2162	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TDE_2162	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TDE_2163	COG2738	Putative neutral zinc metallopeptidase
TDE_2165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TDE_2171	COG2226	methyltransferase
TDE_2176	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TDE_2180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TDE_2181	COG0671	phosphoesterase, PA-phosphatase related
TDE_2186	COG1022	Amp-dependent synthetase and ligase
TDE_2189	COG0739	heme binding
TDE_2190	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TDE_2190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TDE_2192	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TDE_2194	COG0156	8-amino-7-oxononanoate synthase activity
TDE_2198	COG0674	pyruvate-flavodoxin oxidoreductase activity
TDE_2198	COG1013	pyruvate-flavodoxin oxidoreductase activity
TDE_2198	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TDE_2198	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TDE_2199	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TDE_2200	COG0626	cystathionine gamma-synthase activity
TDE_2204	COG2056	Na+-H+ antiporter family
TDE_2208	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TDE_2212	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TDE_2215	COG4211	Belongs to the binding-protein-dependent transport system permease family
TDE_2216	COG1129	ABC transporter
TDE_2217	COG1879	ABC-type sugar transport system periplasmic component
TDE_2220	COG0442	prolyl-tRNA aminoacylation
TDE_2226	COG0803	Belongs to the bacterial solute-binding protein 9 family
TDE_2228	COG2195	Cleaves the N-terminal amino acid of tripeptides
TDE_2232	COG1120	ATPase activity
TDE_2233	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TDE_2236	COG4865	methylaspartate mutase activity
TDE_2243	COG3142	Participates in the control of copper homeostasis
TDE_2248	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TDE_2249	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TDE_2257	COG0737	Belongs to the 5'-nucleotidase family
TDE_2264	COG1132	(ABC) transporter
TDE_2271	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TDE_2275	COG0101	tRNA pseudouridine synthase activity
TDE_2277	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TDE_2279	COG1639	'signal transduction protein
TDE_2283	COG0577	efflux transmembrane transporter activity
TDE_2283	COG1136	(ABC) transporter
TDE_2286	COG3956	TIGRFAM MazG family protein
TDE_2287	COG0545	Peptidyl-prolyl cis-trans isomerase
TDE_2289	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TDE_2290	COG1329	Transcriptional regulator
TDE_2291	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TDE_2291	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TDE_2292	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TDE_2295	COG0668	transmembrane transport
TDE_2298	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TDE_2299	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TDE_2300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TDE_2303	COG0792	nuclease activity
TDE_2307	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TDE_2309	COG3604	Transcriptional regulator
TDE_2315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TDE_2317	COG1272	protein, Hemolysin III
TDE_2318	COG0739	heme binding
TDE_2318	COG1196	nuclear chromosome segregation
TDE_2318	COG0741	lytic transglycosylase activity
TDE_2323	COG0668	transmembrane transport
TDE_2324	COG2197	response regulator
TDE_2327	COG0542	response to heat
TDE_2328	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
TDE_2333	COG2949	membrane
TDE_2335	COG0210	DNA helicase
TDE_2336	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
TDE_2339	COG0495	leucyl-tRNA aminoacylation
TDE_2341	COG0750	zinc metalloprotease
TDE_2342	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TDE_2343	COG0575	Belongs to the CDS family
TDE_2344	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TDE_2345	COG0233	cytoplasmic translational termination
TDE_2346	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TDE_2347	COG0052	Belongs to the universal ribosomal protein uS2 family
TDE_2348	COG0424	maF-like protein
TDE_2349	COG1413	lyase activity
TDE_2353	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TDE_2354	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TDE_2355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TDE_2357	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TDE_2359	COG2376	Dihydroxyacetone kinase
TDE_2360	COG2376	Dihydroxyacetone kinase
TDE_2363	COG0410	ABC transporter
TDE_2368	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TDE_2369	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TDE_2372	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TDE_2373	COG2241	protein methyltransferase activity
TDE_2376	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TDE_2378	COG1131	(ABC) transporter
TDE_2381	COG4585	Histidine kinase
TDE_2383	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TDE_2385	COG1181	Belongs to the D-alanine--D-alanine ligase family
TDE_2388	COG0740	serine-type endopeptidase activity
TDE_2389	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TDE_2391	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TDE_2395	COG1847	R3H domain protein
TDE_2396	COG0706	membrane insertase activity
TDE_2398	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TDE_2400	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TDE_2401	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TDE_2403	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TDE_2407	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TDE_2410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TDE_2411	COG0058	SHG alpha-glucan phosphorylase activity
TDE_2420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TDE_2421	COG0085	RNA polymerase activity
TDE_2422	COG0222	ribosome binding
TDE_2423	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TDE_2424	COG0081	regulation of translation
TDE_2425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TDE_2426	COG0250	Participates in transcription elongation, termination and antitermination
TDE_2427	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TDE_2428	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TDE_2438	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TDE_2439	COG1363	Peptidase, m42
TDE_2440	COG2274	protein secretion by the type I secretion system
TDE_2446	COG0281	malic enzyme
TDE_2449	COG3885	ferrous iron binding
TDE_2449	COG2078	PFAM AMMECR1 domain protein
TDE_2450	COG0666	response to abiotic stimulus
TDE_2451	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TDE_2460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TDE_2466	COG0425	Belongs to the sulfur carrier protein TusA family
TDE_2470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TDE_2472	COG2801	Transposase and inactivated derivatives
TDE_2473	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TDE_2475	COG0534	Mate efflux family protein
TDE_2476	COG0549	Belongs to the carbamate kinase family
TDE_2477	COG1921	L-seryl-tRNASec selenium transferase activity
TDE_2478	COG0322	excinuclease ABC activity
TDE_2480	COG0326	Molecular chaperone. Has ATPase activity
TDE_2489	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TDE_2490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TDE_2491	COG1573	uracil-dna glycosylase
TDE_2496	COG0840	transmembrane signaling receptor activity
TDE_2504	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TDE_2510	COG1132	(ABC) transporter
TDE_2511	COG1132	(ABC) transporter
TDE_2512	COG1012	belongs to the aldehyde dehydrogenase family
TDE_2513	COG0357	Ribosomal RNA small subunit methyltransferase G
TDE_2515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TDE_2517	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TDE_2525	COG2604	Protein of unknown function DUF115
TDE_2527	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TDE_2534	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TDE_2546	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TDE_2552	COG1132	(ABC) transporter
TDE_2553	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TDE_2554	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TDE_2558	COG1132	(ABC) transporter
TDE_2559	COG4988	ABC transporter
TDE_2561	COG1121	(ABC) transporter
TDE_2562	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TDE_2568	COG0301	tRNA thio-modification
TDE_2569	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TDE_2570	COG0328	RNA-DNA hybrid ribonuclease activity
TDE_2571	COG4443	Transcriptional Coactivator p15 (PC4)
TDE_2572	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TDE_2573	COG0166	Belongs to the GPI family
TDE_2574	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TDE_2579	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TDE_2580	COG3706	GGDEF domain
TDE_2582	COG3706	GGDEF domain
TDE_2586	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TDE_2589	COG1362	aminopeptidase activity
TDE_2592	COG0724	RNA recognition motif
TDE_2597	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TDE_2599	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TDE_2601	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TDE_2603	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TDE_2605	COG0406	alpha-ribazole phosphatase activity
TDE_2606	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TDE_2609	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TDE_2614	COG1477	protein flavinylation
TDE_2615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TDE_2616	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TDE_2619	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TDE_2622	COG1129	ABC transporter
TDE_2625	COG1132	(ABC) transporter
TDE_2629	COG0747	negative chemotaxis
TDE_2631	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TDE_2641	COG3177	Filamentation induced by cAMP protein fic
TDE_2644	COG0446	pyridine nucleotide-disulphide oxidoreductase
TDE_2646	COG4175	Glycine betaine
TDE_2646	COG3448	diguanylate cyclase activity
TDE_2647	COG0095	Lipoate-protein ligase
TDE_2650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TDE_2658	COG1797	cobyrinic acid a,c-diamide synthase activity
TDE_2659	COG3437	response regulator, receiver
TDE_2659	COG0784	Response regulator, receiver
TDE_2663	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TDE_2665	COG0516	GMP reductase activity
TDE_2668	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TDE_2669	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TDE_2670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TDE_2676	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TDE_2683	COG1191	sigma factor activity
TDE_2685	COG0455	bacterial-type flagellum organization
TDE_2686	COG1419	protein localization to endoplasmic reticulum
TDE_2687	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TDE_2692	COG0504	CTP synthase activity
TDE_2695	COG1747	RNA polymerase binding
TDE_2695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TDE_2706	COG2211	Major facilitator Superfamily
TDE_2713	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TDE_2716	COG0546	phosphoglycolate phosphatase activity
TDE_2718	COG2239	Acts as a magnesium transporter
TDE_2720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TDE_2723	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TDE_2725	COG3706	GGDEF domain
TDE_2725	COG0745	RESPONSE REGULATOR receiver
TDE_2726	COG2199	diguanylate cyclase activity
TDE_2726	COG2203	Gaf domain
TDE_2730	COG0084	hydrolase, TatD family'
TDE_2731	COG3116	cell division
TDE_2731	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TDE_2742	COG4974	Belongs to the 'phage' integrase family
TDE_2746	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TDE_2750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TDE_2752	COG4545	Glutaredoxin-related protein
TDE_2753	COG0739	heme binding
TDE_2754	COG2423	ornithine cyclodeaminase activity
TDE_2756	COG4166	transmembrane transport
TDE_2758	COG2361	Protein of unknown function DUF86
TDE_2760	COG1338	Plays a role in the flagellum-specific transport system
TDE_2762	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TDE_2762	COG1776	CheC inhibitor of MCP methylation
TDE_2763	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TDE_2764	COG1580	Controls the rotational direction of flagella during chemotaxis
TDE_2765	COG1360	Flagellar Motor Protein
TDE_2766	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TDE_2769	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TDE_2772	COG1132	(ABC) transporter
TDE_2781	COG1132	(ABC) transporter
TDE_2782	COG1132	(ABC) transporter
TDE_2783	COG0840	transmembrane signaling receptor activity
TDE_2786	COG0587	DNA-directed DNA polymerase activity