locus-tag	class	description
C5N99_00005	COG0732	type I restriction modification DNA specificity domain
C5N99_00015	COG0732	type I restriction modification DNA specificity domain
C5N99_00020	COG4974	Belongs to the 'phage' integrase family
C5N99_00035	COG0732	type I restriction modification DNA specificity domain
C5N99_00055	COG2703	oxygen carrier activity
C5N99_00105	COG0813	purine-nucleoside phosphorylase activity
C5N99_00130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C5N99_00135	COG3639	organic phosphonate transmembrane transporter activity
C5N99_00155	COG1187	pseudouridine synthase activity
C5N99_00160	COG0840	transmembrane signaling receptor activity
C5N99_00180	COG1129	ABC transporter
C5N99_00185	COG1609	Transcriptional regulator
C5N99_00195	COG0546	phosphoglycolate phosphatase activity
C5N99_00230	COG1253	flavin adenine dinucleotide binding
C5N99_00235	COG0840	transmembrane signaling receptor activity
C5N99_00250	COG0756	dUTP diphosphatase activity
C5N99_00255	COG1185	polyribonucleotide nucleotidyltransferase activity
C5N99_00265	COG0196	riboflavin kinase activity
C5N99_00275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C5N99_00280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C5N99_00290	COG0779	Required for maturation of 30S ribosomal subunits
C5N99_00310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C5N99_00310	COG1713	HD superfamily hydrolase involved in NAD metabolism
C5N99_00320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5N99_00325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5N99_00335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C5N99_00340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5N99_00345	COG0571	ribonuclease III activity
C5N99_00350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5N99_00355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C5N99_00375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C5N99_00390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5N99_00405	COG1921	L-seryl-tRNASec selenium transferase activity
C5N99_00420	COG0840	transmembrane signaling receptor activity
C5N99_00435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5N99_00445	COG1012	belongs to the aldehyde dehydrogenase family
C5N99_00450	COG1960	acyl-CoA dehydrogenase activity
C5N99_00470	COG1598	PFAM Uncharacterised protein family UPF0150
C5N99_00505	COG2887	Belongs to the helicase family. UvrD subfamily
C5N99_00515	COG0300	oxidoreductase activity
C5N99_00545	COG0681	Belongs to the peptidase S26 family
C5N99_00555	COG0740	serine-type endopeptidase activity
C5N99_00560	COG0556	nucleotide-excision repair
C5N99_00570	COG0709	Synthesizes selenophosphate from selenide and ATP
C5N99_00595	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C5N99_00610	COG1744	ABC transporter substrate-binding protein PnrA-like
C5N99_00615	COG3845	ABC transporter
C5N99_00620	COG4603	Belongs to the binding-protein-dependent transport system permease family
C5N99_00625	COG1079	Belongs to the binding-protein-dependent transport system permease family
C5N99_00645	COG2361	Protein of unknown function DUF86
C5N99_00680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C5N99_00685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5N99_00690	COG4251	negative regulation of phosphorylation
C5N99_00690	COG2203	Gaf domain
C5N99_00690	COG3706	GGDEF domain
C5N99_00690	COG5001	Diguanylate cyclase
C5N99_00695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5N99_00700	COG0205	6-phosphofructokinase activity
C5N99_00705	COG0124	histidyl-tRNA synthetase
C5N99_00720	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C5N99_00730	COG0840	transmembrane signaling receptor activity
C5N99_00760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5N99_00775	COG0395	ABC-type sugar transport system, permease component
C5N99_00780	COG1175	transmembrane transport
C5N99_00790	COG3437	response regulator, receiver
C5N99_00790	COG2770	Histidine kinase
C5N99_00795	COG1214	PFAM Peptidase M22, glycoprotease
C5N99_00800	COG0802	atpase or kinase
C5N99_00805	COG0564	pseudouridine synthase activity
C5N99_00815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5N99_00830	COG0297	glycogen (starch) synthase activity
C5N99_00865	COG1027	Aspartate ammonia-lyase
C5N99_00870	COG0295	cytidine deaminase activity
C5N99_00880	COG0739	heme binding
C5N99_00925	COG3876	Protein conserved in bacteria
C5N99_00940	COG2239	Acts as a magnesium transporter
C5N99_00945	COG0170	dolichyl monophosphate biosynthetic process
C5N99_00965	COG0346	lactoylglutathione lyase activity
C5N99_00980	COG2252	PERMEase
C5N99_00995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5N99_01000	COG0443	Heat shock 70 kDa protein
C5N99_01005	COG0484	heat shock protein binding
C5N99_01030	COG1715	Restriction endonuclease
C5N99_01040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5N99_01045	COG0483	inositol monophosphate 1-phosphatase activity
C5N99_01050	COG3842	ATPase activity
C5N99_01065	COG0674	pyruvate-flavodoxin oxidoreductase activity
C5N99_01065	COG1013	pyruvate-flavodoxin oxidoreductase activity
C5N99_01065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C5N99_01065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C5N99_01075	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5N99_01080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5N99_01095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5N99_01100	COG3549	Plasmid maintenance system killer
C5N99_01120	COG0318	PFAM AMP-dependent synthetase and ligase
C5N99_01130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C5N99_01150	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
C5N99_01160	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
C5N99_01165	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
C5N99_01170	COG1394	ATPase activity, coupled to movement of substances
C5N99_01175	COG1269	ATP hydrolysis coupled proton transport
C5N99_01185	COG0840	transmembrane signaling receptor activity
C5N99_01195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5N99_01205	COG0840	transmembrane signaling receptor activity
C5N99_01225	COG1199	ATP-dependent helicase activity
C5N99_01235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C5N99_01245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5N99_01260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5N99_01265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C5N99_01270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5N99_01280	COG0840	transmembrane signaling receptor activity
C5N99_01300	COG1475	DNA binding
C5N99_01305	COG1192	Involved in chromosome partitioning
C5N99_01310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5N99_01325	COG0427	acetyl-CoA hydrolase
C5N99_01330	COG1024	Enoyl-CoA hydratase
C5N99_01335	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5N99_01415	COG2244	polysaccharide biosynthetic process
C5N99_01440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5N99_01475	COG1373	ATPase (AAA superfamily
C5N99_01505	COG1362	aminopeptidase activity
C5N99_01510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C5N99_01525	COG2217	Heavy metal translocating P-type atpase
C5N99_01535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5N99_01555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5N99_01595	COG0670	Belongs to the BI1 family
C5N99_01600	COG0180	Tryptophanyl-tRNA synthetase
C5N99_01605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C5N99_01655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C5N99_01675	COG1191	sigma factor activity
C5N99_01685	COG0840	transmembrane signaling receptor activity
C5N99_01690	COG0433	COG0433 Predicted ATPase
C5N99_01695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5N99_01700	COG1722	exodeoxyribonuclease VII activity
C5N99_01800	COG0733	neurotransmitter:sodium symporter activity
C5N99_01805	COG0457	Tetratricopeptide repeat
C5N99_01810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C5N99_01815	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C5N99_01825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5N99_01830	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C5N99_01845	COG0058	SHG alpha-glucan phosphorylase activity
C5N99_01855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5N99_01865	COG1040	competence protein
C5N99_01870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5N99_01875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5N99_01885	COG1862	Preprotein translocase
C5N99_01890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5N99_01900	COG1847	R3H domain protein
C5N99_01905	COG0706	membrane insertase activity
C5N99_01910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C5N99_01955	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C5N99_01960	COG1472	Belongs to the glycosyl hydrolase 3 family
C5N99_01965	COG0492	ferredoxin-NADP+ reductase activity
C5N99_01970	COG0280	phosphate acetyltransferase
C5N99_01990	COG0459	protein refolding
C5N99_02005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5N99_02010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5N99_02015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C5N99_02015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C5N99_02030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5N99_02045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5N99_02055	COG0728	peptidoglycan biosynthetic process
C5N99_02075	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5N99_02080	COG0420	3'-5' exonuclease activity
C5N99_02085	COG0419	ATPase involved in DNA repair
C5N99_02095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5N99_02120	COG0588	phosphoglycerate mutase activity
C5N99_02125	COG0564	pseudouridine synthase activity
C5N99_02155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5N99_02180	COG2378	regulation of single-species biofilm formation
C5N99_02200	COG4443	Transcriptional Coactivator p15 (PC4)
C5N99_02205	COG0840	transmembrane signaling receptor activity
C5N99_02215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C5N99_02215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C5N99_02220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C5N99_02240	COG1309	transcriptional regulator
C5N99_02290	COG5433	transposase activity
C5N99_02295	COG1647	Serine aminopeptidase, S33
C5N99_02305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5N99_02310	COG1028	Short-chain dehydrogenase reductase Sdr
C5N99_02340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C5N99_02345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5N99_02370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5N99_02375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5N99_02380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5N99_02385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C5N99_02390	COG2878	Part of a membrane complex involved in electron transport
C5N99_02390	COG1245	4Fe-4S binding domain
C5N99_02395	COG4657	Part of a membrane complex involved in electron transport
C5N99_02400	COG4660	Part of a membrane complex involved in electron transport
C5N99_02405	COG4659	FMN binding
C5N99_02410	COG4658	electron transport chain
C5N99_02415	COG4656	Part of a membrane complex involved in electron transport
C5N99_02420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5N99_02435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C5N99_02440	COG0825	malonyl-CoA metabolic process
C5N99_02450	COG0540	Belongs to the ATCase OTCase family
C5N99_02455	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C5N99_02460	COG0543	2 iron, 2 sulfur cluster binding
C5N99_02465	COG0167	dihydroorotate dehydrogenase activity
C5N99_02470	COG0284	orotidine-5'-phosphate decarboxylase activity
C5N99_02475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C5N99_02480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5N99_02490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5N99_02500	COG0613	PHP domain protein
C5N99_02530	COG1193	negative regulation of DNA recombination
C5N99_02540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C5N99_02580	COG0629	single-stranded DNA binding
C5N99_02585	COG0281	malic enzyme
C5N99_02590	COG0039	L-malate dehydrogenase activity
C5N99_02645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C5N99_02655	COG0513	Belongs to the DEAD box helicase family
C5N99_02670	COG0395	ABC-type sugar transport system, permease component
C5N99_02675	COG1175	transmembrane transport
C5N99_02695	COG1070	Carbohydrate kinase
C5N99_02710	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5N99_02720	COG1879	ABC-type sugar transport system periplasmic component
C5N99_02740	COG2011	ABC-type metal ion transport system permease component
C5N99_02750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5N99_02755	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C5N99_02760	COG3850	Histidine kinase
C5N99_02760	COG5002	protein histidine kinase activity
C5N99_02780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5N99_02780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C5N99_02790	COG0351	phosphomethylpyrimidine kinase
C5N99_02830	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C5N99_02885	COG0640	Transcriptional regulator
C5N99_02890	COG2217	Heavy metal translocating P-type atpase
C5N99_02895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5N99_02940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C5N99_02950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5N99_02980	COG3340	Belongs to the peptidase S51 family
C5N99_03005	COG0583	DNA-binding transcription factor activity
C5N99_03050	COG0783	Belongs to the Dps family
C5N99_03060	COG0793	Belongs to the peptidase S41A family
C5N99_03080	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C5N99_03085	COG0840	transmembrane signaling receptor activity
C5N99_03095	COG0203	ribosomal protein L17
C5N99_03100	COG0202	RNA polymerase activity
C5N99_03105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5N99_03115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5N99_03125	COG0200	Binds to the 23S rRNA
C5N99_03135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C5N99_03145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C5N99_03150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C5N99_03160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5N99_03165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C5N99_03170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C5N99_03175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C5N99_03180	COG0255	Belongs to the universal ribosomal protein uL29 family
C5N99_03190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C5N99_03195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C5N99_03205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5N99_03210	COG0089	rRNA binding
C5N99_03215	COG0088	Forms part of the polypeptide exit tunnel
C5N99_03220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C5N99_03225	COG0051	transcription antitermination factor activity, RNA binding
C5N99_03230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5N99_03245	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5N99_03250	COG0725	ABC transporter, periplasmic molybdate-binding protein
C5N99_03255	COG4149	molybdate abc transporter
C5N99_03315	COG0741	lytic transglycosylase activity
C5N99_03320	COG1968	undecaprenyl-diphosphatase activity
C5N99_03325	COG1674	ftsk spoiiie
C5N99_03350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5N99_03355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5N99_03360	COG0084	hydrolase, TatD family'
C5N99_03370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5N99_03435	COG0714	Associated with various cellular activities
C5N99_03465	COG0826	peptidase U32
C5N99_03475	COG0822	iron-sulfur transferase activity
C5N99_03485	COG2255	four-way junction helicase activity
C5N99_03495	COG0445	tRNA wobble uridine modification
C5N99_03505	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C5N99_03520	COG1757	Na H antiporter
C5N99_03525	COG2199	diguanylate cyclase activity
C5N99_03525	COG2203	Gaf domain
C5N99_03530	COG3706	GGDEF domain
C5N99_03580	COG5433	transposase activity
C5N99_03605	COG1054	Belongs to the UPF0176 family
C5N99_03610	COG0024	Methionine aminopeptidase
C5N99_03615	COG0484	heat shock protein binding
C5N99_03635	COG0204	Acyl-transferase
C5N99_03635	COG0318	PFAM AMP-dependent synthetase and ligase
C5N99_03645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5N99_03670	COG3041	Addiction module toxin RelE StbE family
C5N99_03675	COG2986	histidine ammonia-lyase
C5N99_03700	COG2801	Transposase and inactivated derivatives
C5N99_03715	COG1028	Short-chain dehydrogenase reductase Sdr
C5N99_03720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5N99_03725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5N99_03740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5N99_03780	COG5433	transposase activity
C5N99_03815	COG0739	heme binding
C5N99_03845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5N99_03850	COG1129	ABC transporter
C5N99_03875	COG4977	sequence-specific DNA binding
C5N99_03875	COG1917	Cupin 2, conserved barrel domain protein
C5N99_03880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5N99_03935	COG1337	RAMP superfamily
C5N99_03960	COG1518	maintenance of DNA repeat elements
C5N99_03965	COG1401	restriction endodeoxyribonuclease activity
C5N99_03980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C5N99_04010	COG5433	transposase activity
C5N99_04030	COG2089	acid synthase
C5N99_04035	COG0592	DNA-directed DNA polymerase activity
C5N99_04040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C5N99_04065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C5N99_04110	COG2378	regulation of single-species biofilm formation
C5N99_04120	COG0545	Peptidyl-prolyl cis-trans isomerase
C5N99_04125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5N99_04145	COG0739	heme binding
C5N99_04150	COG1686	Belongs to the peptidase S11 family
C5N99_04170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5N99_04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5N99_04205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5N99_04255	COG2204	response regulator
C5N99_04260	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C5N99_04265	COG1028	Short-chain dehydrogenase reductase Sdr
C5N99_04275	COG0516	GMP reductase activity
C5N99_04275	COG0517	IMP dehydrogenase activity
C5N99_04280	COG0205	6-phosphofructokinase activity
C5N99_04290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C5N99_04290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C5N99_04295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5N99_04300	COG0423	glycine-tRNA ligase activity
C5N99_04310	COG0584	glycerophosphoryl diester phosphodiesterase
C5N99_04375	COG2183	response to ionizing radiation
C5N99_04390	COG0012	GTP binding
C5N99_04395	COG0326	Molecular chaperone. Has ATPase activity
C5N99_04400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C5N99_04415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5N99_04420	COG1120	ATPase activity
C5N99_04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5N99_04470	COG0156	8-amino-7-oxononanoate synthase activity
C5N99_04475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5N99_04500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C5N99_04505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C5N99_04510	COG1114	Component of the transport system for branched-chain amino acids
C5N99_04515	COG0840	transmembrane signaling receptor activity
C5N99_04520	COG0739	heme binding
C5N99_04530	COG0237	dephospho-CoA kinase activity
C5N99_04550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5N99_04555	COG4452	Inner membrane protein CreD
C5N99_04570	COG1640	4-alpha-glucanotransferase
C5N99_04585	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5N99_04585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5N99_04635	COG1983	PspC domain protein
C5N99_04645	COG1695	Transcriptional regulator
C5N99_04650	COG1121	(ABC) transporter
C5N99_04655	COG1639	'signal transduction protein
C5N99_04660	COG0543	2 iron, 2 sulfur cluster binding
C5N99_04675	COG0733	neurotransmitter:sodium symporter activity
C5N99_04690	COG0425	Belongs to the sulfur carrier protein TusA family
C5N99_04705	COG1879	ABC-type sugar transport system periplasmic component
C5N99_04720	COG0438	transferase activity, transferring glycosyl groups
C5N99_04720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5N99_04730	COG5016	pyruvate
C5N99_04730	COG0511	ligase activity, forming carbon-carbon bonds
C5N99_04755	COG1131	(ABC) transporter
C5N99_04775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5N99_04810	COG4656	Part of a membrane complex involved in electron transport
C5N99_04820	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C5N99_04825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5N99_04840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C5N99_04855	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C5N99_04855	COG3608	succinylglutamate desuccinylase aspartoacylase
C5N99_04875	COG0488	(ABC) transporter
C5N99_04880	COG1115	amino acid carrier protein
C5N99_04885	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5N99_04890	COG3437	response regulator, receiver
C5N99_04895	COG1671	Belongs to the UPF0178 family
C5N99_04900	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C5N99_04915	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C5N99_05015	COG0701	Predicted permease
C5N99_05020	COG0116	Belongs to the methyltransferase superfamily
C5N99_05045	COG0542	response to heat
C5N99_05065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5N99_05075	COG0450	alkyl hydroperoxide reductase
C5N99_05105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5N99_05125	COG3177	Filamentation induced by cAMP protein fic
C5N99_05140	COG4942	peptidase
C5N99_05145	COG1079	Belongs to the binding-protein-dependent transport system permease family
C5N99_05150	COG4603	Belongs to the binding-protein-dependent transport system permease family
C5N99_05155	COG1129	ABC transporter
C5N99_05160	COG1744	ABC transporter substrate-binding protein PnrA-like
C5N99_05170	COG3842	ATPase activity
C5N99_05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5N99_05180	COG1177	transmembrane transport
C5N99_05205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C5N99_05210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5N99_05220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5N99_05225	COG4750	Nucleotidyl transferase
C5N99_05230	COG1129	ABC transporter
C5N99_05250	COG2211	Major facilitator Superfamily
C5N99_05270	COG0071	Belongs to the small heat shock protein (HSP20) family
C5N99_05280	COG0716	FMN binding
C5N99_05290	COG1956	GAF domain-containing protein
C5N99_05305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5N99_05310	COG1136	(ABC) transporter
C5N99_05330	COG0561	phosphatase activity
C5N99_05340	COG0577	efflux transmembrane transporter activity
C5N99_05350	COG1136	(ABC) transporter
C5N99_05350	COG0577	efflux transmembrane transporter activity
C5N99_05390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5N99_05400	COG1132	(ABC) transporter
C5N99_05430	COG2815	serine threonine protein kinase
C5N99_05430	COG0515	serine threonine protein kinase
C5N99_05435	COG1002	Type II restriction enzyme, methylase subunits
C5N99_05440	COG1002	Type II restriction enzyme, methylase subunits
C5N99_05475	COG1132	(ABC) transporter
C5N99_05485	COG1162	GTPase activity
C5N99_05490	COG1309	transcriptional regulator
C5N99_05495	COG1132	(ABC) transporter
C5N99_05500	COG1132	(ABC) transporter
C5N99_05505	COG1132	(ABC) transporter
C5N99_05510	COG1132	(ABC) transporter
C5N99_05515	COG1129	ABC transporter
C5N99_05530	COG1132	(ABC) transporter
C5N99_05535	COG2375	cellular response to nickel ion
C5N99_05535	COG1132	(ABC) transporter
C5N99_05540	COG4753	response regulator
C5N99_05540	COG2207	Transcriptional regulator
C5N99_05555	COG1129	ABC transporter
C5N99_05590	COG1132	(ABC) transporter
C5N99_05595	COG1132	(ABC) transporter
C5N99_05625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5N99_05640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C5N99_05655	COG0653	protein targeting
C5N99_05670	COG1102	Psort location Cytoplasmic, score
C5N99_05690	COG0534	Mate efflux family protein
C5N99_05705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5N99_05745	COG0544	peptidyl-prolyl cis-trans isomerase activity
C5N99_05750	COG0740	serine-type endopeptidase activity
C5N99_05755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C5N99_05765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C5N99_05785	COG0395	ABC-type sugar transport system, permease component
C5N99_05790	COG4209	transmembrane transport
C5N99_05820	COG1129	ABC transporter
C5N99_05845	COG2267	carboxylic ester hydrolase activity
C5N99_05860	COG0481	GTPase activity
C5N99_05875	COG0018	arginyl-trna synthetase
C5N99_05880	COG2235	arginine
C5N99_05885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5N99_05890	COG0549	Belongs to the carbamate kinase family
C5N99_05895	COG1288	antiporter activity
C5N99_05905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5N99_05935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5N99_05940	COG0017	Asparaginyl-tRNA synthetase
C5N99_05955	COG1733	regulation of RNA biosynthetic process
C5N99_05990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5N99_06005	COG3118	belongs to the thioredoxin family
C5N99_06010	COG1692	metallophosphoesterase
C5N99_06015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5N99_06025	COG0719	Fe-S assembly protein
C5N99_06055	COG1570	exodeoxyribonuclease VII activity
C5N99_06065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5N99_06075	COG1744	ABC transporter substrate-binding protein PnrA-like
C5N99_06080	COG3845	ABC transporter
C5N99_06090	COG1079	Belongs to the binding-protein-dependent transport system permease family
C5N99_06100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5N99_06105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5N99_06115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5N99_06130	COG1879	ABC-type sugar transport system periplasmic component
C5N99_06135	COG1129	ABC transporter
C5N99_06140	COG4211	Belongs to the binding-protein-dependent transport system permease family
C5N99_06160	COG1309	transcriptional regulator
C5N99_06165	COG3848	Pyruvate phosphate dikinase
C5N99_06165	COG0574	Belongs to the PEP-utilizing enzyme family
C5N99_06170	COG0534	Mate efflux family protein
C5N99_06175	COG0668	transmembrane transport
C5N99_06185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C5N99_06190	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C5N99_06225	COG1418	mRNA catabolic process
C5N99_06230	COG0457	Tetratricopeptide repeat
C5N99_06235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C5N99_06260	COG0494	nUDIX hydrolase
C5N99_06275	COG0681	Belongs to the peptidase S26 family
C5N99_06280	COG0768	penicillin binding
C5N99_06285	COG2604	Protein of unknown function DUF115
C5N99_06325	COG1254	Belongs to the acylphosphatase family
C5N99_06370	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5N99_06375	COG1966	Carbon starvation protein
C5N99_06435	COG0402	S-adenosylhomocysteine deaminase activity
C5N99_06440	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C5N99_06445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C5N99_06450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C5N99_06465	COG0826	peptidase U32
C5N99_06480	COG0601	transmembrane transport
C5N99_06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5N99_06490	COG0444	Belongs to the ABC transporter superfamily
C5N99_06495	COG4608	Belongs to the ABC transporter superfamily
C5N99_06500	COG0616	signal peptide processing
C5N99_06530	COG1129	ABC transporter
C5N99_06560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5N99_06565	COG2801	Transposase and inactivated derivatives
C5N99_06575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5N99_06590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5N99_06595	COG1438	arginine binding
C5N99_06630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5N99_06640	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5N99_06645	COG0250	Participates in transcription elongation, termination and antitermination
C5N99_06650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5N99_06655	COG0081	regulation of translation
C5N99_06660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5N99_06665	COG0222	ribosome binding
C5N99_06670	COG0085	RNA polymerase activity
C5N99_06685	COG0049	tRNA binding
C5N99_06700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5N99_06710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5N99_06720	COG0217	transcriptional regulatory protein
C5N99_06760	COG0587	DNA-directed DNA polymerase activity
C5N99_06775	COG0762	integral membrane protein
C5N99_06785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5N99_06790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C5N99_06795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5N99_06815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5N99_06840	COG1774	PSP1 C-terminal conserved region
C5N99_06855	COG0739	heme binding
C5N99_06865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5N99_06870	COG2911	Protein conserved in bacteria
C5N99_06875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5N99_06885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5N99_06900	COG0739	heme binding
C5N99_06930	COG2502	aspartate--ammonia ligase
C5N99_06940	COG0301	tRNA thio-modification
C5N99_06965	COG0322	excinuclease ABC activity
C5N99_07000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5N99_07050	COG1254	Belongs to the acylphosphatase family
C5N99_07095	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5N99_07100	COG1966	Carbon starvation protein
C5N99_07160	COG0402	S-adenosylhomocysteine deaminase activity
C5N99_07165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C5N99_07170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C5N99_07175	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C5N99_07190	COG0826	peptidase U32
C5N99_07205	COG0601	transmembrane transport
C5N99_07210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5N99_07215	COG0444	Belongs to the ABC transporter superfamily
C5N99_07220	COG4608	Belongs to the ABC transporter superfamily
C5N99_07225	COG0616	signal peptide processing
C5N99_07255	COG1129	ABC transporter
C5N99_07285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5N99_07290	COG2801	Transposase and inactivated derivatives
C5N99_07295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5N99_07310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5N99_07315	COG1438	arginine binding
C5N99_07350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5N99_07360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5N99_07365	COG0250	Participates in transcription elongation, termination and antitermination
C5N99_07370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5N99_07375	COG0081	regulation of translation
C5N99_07380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5N99_07385	COG0222	ribosome binding
C5N99_07390	COG0085	RNA polymerase activity
C5N99_07405	COG0049	tRNA binding
C5N99_07420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5N99_07430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5N99_07440	COG0217	transcriptional regulatory protein
C5N99_07480	COG0587	DNA-directed DNA polymerase activity
C5N99_07495	COG0762	integral membrane protein
C5N99_07505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5N99_07510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C5N99_07515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5N99_07535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5N99_07560	COG1774	PSP1 C-terminal conserved region
C5N99_07575	COG0739	heme binding
C5N99_07585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5N99_07590	COG2911	Protein conserved in bacteria
C5N99_07595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5N99_07605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5N99_07620	COG0739	heme binding
C5N99_07650	COG2502	aspartate--ammonia ligase
C5N99_07660	COG0301	tRNA thio-modification
C5N99_07685	COG0322	excinuclease ABC activity
C5N99_07720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5N99_07755	COG0488	(ABC) transporter
C5N99_07765	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C5N99_07780	COG2801	Transposase and inactivated derivatives
C5N99_07785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C5N99_07790	COG0363	glucosamine-6-phosphate deaminase activity
C5N99_07795	COG0628	permease
C5N99_07800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5N99_07805	COG0328	RNA-DNA hybrid ribonuclease activity
C5N99_07810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5N99_07820	COG1175	transmembrane transport
C5N99_07825	COG0395	ABC-type sugar transport system, permease component
C5N99_07855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5N99_07870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C5N99_07870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C5N99_07890	COG1598	PFAM Uncharacterised protein family UPF0150
C5N99_07905	COG0737	Belongs to the 5'-nucleotidase family
C5N99_07915	COG0537	adenosine 5'-monophosphoramidase activity
C5N99_07920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C5N99_07925	COG2088	sporulation resulting in formation of a cellular spore
C5N99_07935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C5N99_07945	COG0457	Tetratricopeptide repeat
C5N99_07950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5N99_07965	COG0840	transmembrane signaling receptor activity
C5N99_07975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5N99_07980	COG0786	glutamate:sodium symporter activity
C5N99_07990	COG4770	biotin carboxylase activity
C5N99_07995	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C5N99_08000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5N99_08005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5N99_08010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5N99_08020	COG1924	4 iron, 4 sulfur cluster binding
C5N99_08025	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C5N99_08030	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C5N99_08040	COG0735	belongs to the Fur family
C5N99_08055	COG0494	nUDIX hydrolase
C5N99_08080	COG1480	7TM receptor with intracellular HD hydrolase
C5N99_08085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C5N99_08115	COG0426	domain, Protein
C5N99_08115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5N99_08120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5N99_08130	COG0318	PFAM AMP-dependent synthetase and ligase
C5N99_08135	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5N99_08140	COG0574	Belongs to the PEP-utilizing enzyme family
C5N99_08140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5N99_08160	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C5N99_08170	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5N99_08200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5N99_08210	COG0126	phosphoglycerate kinase activity
C5N99_08255	COG2201	protein-glutamate methylesterase activity
C5N99_08270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5N99_08275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C5N99_08280	COG0215	cysteine-tRNA ligase activity
C5N99_08295	COG1305	Transglutaminase-like
C5N99_08300	COG0528	UMP kinase activity
C5N99_08305	COG0484	heat shock protein binding
C5N99_08310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5N99_08315	COG2801	Transposase and inactivated derivatives
C5N99_08335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5N99_08350	COG0457	Tetratricopeptide repeat
C5N99_08355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C5N99_08360	COG3118	belongs to the thioredoxin family
C5N99_08365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C5N99_08365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5N99_08405	COG0395	ABC-type sugar transport system, permease component
C5N99_08410	COG1175	transmembrane transport
C5N99_08415	COG1653	transport
C5N99_08435	COG2971	BadF BadG BcrA BcrD
C5N99_08445	COG1573	uracil-dna glycosylase
C5N99_08450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5N99_08455	COG1482	cell wall glycoprotein biosynthetic process
C5N99_08470	COG1413	lyase activity
C5N99_08485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5N99_08490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C5N99_08500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5N99_08500	COG0302	gtp cyclohydrolase
C5N99_08520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C5N99_08530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C5N99_08540	COG0455	bacterial-type flagellum organization
C5N99_08550	COG0811	peptide transport
C5N99_08555	COG0848	biopolymer transport protein
C5N99_08610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5N99_08615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C5N99_08620	COG0187	DNA topoisomerase II activity
C5N99_08675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C5N99_08690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5N99_08695	COG1360	Flagellar Motor Protein
C5N99_08700	COG1580	Controls the rotational direction of flagella during chemotaxis
C5N99_08705	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5N99_08710	COG1776	CheC inhibitor of MCP methylation
C5N99_08710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5N99_08720	COG1338	Plays a role in the flagellum-specific transport system
C5N99_08725	COG1987	bacterial-type flagellum assembly
C5N99_08730	COG1684	flagellar biosynthetic protein fliR
C5N99_08735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5N99_08740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5N99_08745	COG1419	protein localization to endoplasmic reticulum
C5N99_08755	COG0534	Mate efflux family protein
C5N99_08765	COG0557	exoribonuclease II activity
C5N99_08770	COG3177	Filamentation induced by cAMP protein fic
C5N99_08775	COG1362	aminopeptidase activity
C5N99_08785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C5N99_08785	COG3608	succinylglutamate desuccinylase aspartoacylase
C5N99_08790	COG0525	valine-tRNA ligase activity
C5N99_08835	COG4974	Belongs to the 'phage' integrase family
C5N99_08840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5N99_08840	COG0551	DNA topoisomerase type I activity
C5N99_08845	COG0758	DNA mediated transformation
C5N99_08855	COG0475	glutathione-regulated potassium exporter activity
C5N99_08860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5N99_08865	COG3579	cysteine-type endopeptidase activity
C5N99_08880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C5N99_08885	COG0166	Belongs to the GPI family
C5N99_08890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5N99_08930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C5N99_08940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5N99_08945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5N99_08945	COG0574	Belongs to the PEP-utilizing enzyme family
C5N99_08960	COG2304	oxidoreductase activity
C5N99_08970	COG0183	Belongs to the thiolase family
C5N99_08985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5N99_08985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5N99_08995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C5N99_09000	COG1773	rubredoxin
C5N99_09010	COG0495	leucyl-tRNA aminoacylation
C5N99_09050	COG0335	large ribosomal subunit rRNA binding
C5N99_09055	COG0336	Belongs to the RNA methyltransferase TrmD family
C5N99_09060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5N99_09065	COG1837	Belongs to the UPF0109 family
C5N99_09070	COG0228	four-way junction DNA binding
C5N99_09100	COG0395	ABC-type sugar transport system, permease component
C5N99_09105	COG4209	transmembrane transport
C5N99_09130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5N99_09180	COG0785	Cytochrome C biogenesis protein
C5N99_09185	COG0583	DNA-binding transcription factor activity
C5N99_09210	COG2337	Toxic component of a toxin-antitoxin (TA) module
C5N99_09220	COG2885	chlorophyll binding
C5N99_09225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5N99_09235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C5N99_09265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5N99_09280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5N99_09295	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C5N99_09310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5N99_09315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C5N99_09320	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5N99_09335	COG1522	sequence-specific DNA binding
C5N99_09340	COG0436	Aminotransferase
C5N99_09345	COG0561	phosphatase activity
C5N99_09355	COG4608	Belongs to the ABC transporter superfamily
C5N99_09360	COG0601	transmembrane transport
C5N99_09365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5N99_09395	COG1876	peptidase activity
C5N99_09400	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5N99_09410	COG1268	BioY protein
C5N99_09415	COG1122	ATPase activity
C5N99_09440	COG0552	protein localization to endoplasmic reticulum
C5N99_09450	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5N99_09455	COG1136	(ABC) transporter
C5N99_09465	COG0142	geranyltranstransferase activity
C5N99_09470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C5N99_09475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5N99_09695	COG1078	dGTPase activity
C5N99_09760	COG0724	RNA recognition motif
C5N99_09765	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5N99_09775	COG1196	nuclear chromosome segregation
C5N99_09780	COG0504	CTP synthase activity
C5N99_09805	COG0482	sulfurtransferase activity
C5N99_09815	COG0457	Tetratricopeptide repeat
C5N99_09820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5N99_09825	COG0733	neurotransmitter:sodium symporter activity
C5N99_09830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5N99_09830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5N99_09830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5N99_09855	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C5N99_09910	COG0534	Mate efflux family protein
C5N99_09915	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C5N99_09930	COG0357	Ribosomal RNA small subunit methyltransferase G
C5N99_09940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5N99_09945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5N99_09960	COG0708	Exodeoxyribonuclease III
C5N99_09980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5N99_09980	COG1747	RNA polymerase binding
C5N99_09990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5N99_09995	COG3956	TIGRFAM MazG family protein
C5N99_10005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5N99_10010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C5N99_10020	COG0736	holo-[acyl-carrier-protein] synthase activity
C5N99_10030	COG0101	tRNA pseudouridine synthase activity
C5N99_10040	COG1704	LemA family
C5N99_10050	COG1132	(ABC) transporter
C5N99_10065	COG1132	(ABC) transporter
C5N99_10070	COG1132	(ABC) transporter
C5N99_10075	COG2186	Transcriptional regulator
C5N99_10080	COG1802	Transcriptional regulator
C5N99_10085	COG0632	four-way junction helicase activity
C5N99_10090	COG1739	Uncharacterized protein family UPF0029
C5N99_10095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C5N99_10100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5N99_10110	COG0470	DNA polymerase III
C5N99_10120	COG2604	Protein of unknown function DUF115
C5N99_10125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5N99_10130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5N99_10145	COG2161	toxin-antitoxin pair type II binding
C5N99_10150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5N99_10170	COG2211	Major facilitator Superfamily
C5N99_10180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5N99_10185	COG0154	amidase activity
C5N99_10190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5N99_10200	COG4254	PFAM FecR protein
C5N99_10210	COG1234	tRNA 3'-trailer cleavage
C5N99_10225	COG1454	alcohol dehydrogenase
C5N99_10250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5N99_10255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5N99_10260	COG0427	acetyl-CoA hydrolase
C5N99_10300	COG0497	DNA recombination
C5N99_10305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5N99_10310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5N99_10315	COG0835	chemotaxis
C5N99_10325	COG5341	Protein conserved in bacteria
C5N99_10330	COG0442	prolyl-tRNA aminoacylation
C5N99_10340	COG0424	maF-like protein
C5N99_10345	COG0052	Belongs to the universal ribosomal protein uS2 family
C5N99_10350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C5N99_10355	COG0233	cytoplasmic translational termination
C5N99_10360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5N99_10365	COG0575	Belongs to the CDS family
C5N99_10370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C5N99_10375	COG0750	zinc metalloprotease
C5N99_10390	COG1309	transcriptional regulator
C5N99_10400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5N99_10435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5N99_10440	COG0714	Associated with various cellular activities
C5N99_10455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5N99_10460	COG2890	protein-(glutamine-N5) methyltransferase activity
C5N99_10465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5N99_10470	COG0666	response to abiotic stimulus
C5N99_10480	COG3330	Domain of unknown function (DUF4912)
C5N99_10485	COG1543	Belongs to the glycosyl hydrolase 57 family
C5N99_10490	COG0588	phosphoglycerate mutase activity
C5N99_10495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5N99_10505	COG1131	(ABC) transporter
C5N99_10520	COG4886	Leucine-rich repeat (LRR) protein
C5N99_10525	COG1131	(ABC) transporter
C5N99_10555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C5N99_10560	COG1104	cysteine desulfurase activity
C5N99_10565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C5N99_10575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5N99_10580	COG2208	phosphoserine phosphatase activity
C5N99_10610	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C5N99_10615	COG1321	iron dependent repressor
C5N99_10620	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5N99_10625	COG1121	(ABC) transporter
C5N99_10630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5N99_10635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5N99_10640	COG1683	Conserved Protein
C5N99_10650	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C5N99_10660	COG3290	protein histidine kinase activity
C5N99_10660	COG3829	transcription factor binding
C5N99_10670	COG3852	Histidine kinase
C5N99_10675	COG2204	response regulator
C5N99_10680	COG0823	Involved in the tonB-independent uptake of proteins
C5N99_10705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5N99_10735	COG0149	triose-phosphate isomerase activity
C5N99_10745	COG1760	l-serine dehydratase
C5N99_10750	COG1760	l-serine dehydratase
C5N99_10775	COG0360	Binds together with S18 to 16S ribosomal RNA
C5N99_10780	COG0629	single-stranded DNA binding
C5N99_10785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C5N99_10790	COG0359	binds to the 23S rRNA
C5N99_10795	COG0305	Participates in initiation and elongation during chromosome replication
C5N99_10830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5N99_10845	COG1070	Carbohydrate kinase
C5N99_10865	COG2388	GCN5-related N-acetyl-transferase
C5N99_10875	COG1309	transcriptional regulator
C5N99_10880	COG1620	l-lactate permease
C5N99_10885	COG4166	transmembrane transport
C5N99_10895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C5N99_10905	COG0569	domain protein
C5N99_10910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5N99_10920	COG1067	ATP-dependent peptidase activity
C5N99_10950	COG3142	Participates in the control of copper homeostasis
C5N99_10985	COG1388	LysM domain
C5N99_10985	COG0741	lytic transglycosylase activity
C5N99_11000	COG3876	Protein conserved in bacteria
C5N99_11005	COG1472	Belongs to the glycosyl hydrolase 3 family
C5N99_11030	COG2226	methyltransferase
C5N99_11045	COG0534	Mate efflux family protein
C5N99_11050	COG0523	cobalamin synthesis protein
C5N99_11060	COG3681	Belongs to the UPF0597 family
C5N99_11065	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C5N99_11070	COG1129	ABC transporter
C5N99_11100	COG1222	aaa ATPase
C5N99_11145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5N99_11165	COG1136	(ABC) transporter
C5N99_11170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C5N99_11175	COG0193	aminoacyl-tRNA hydrolase activity
C5N99_11195	COG2832	Protein of unknown function (DUF454)
C5N99_11200	COG1137	ATPase activity
C5N99_11215	COG0493	'glutamate synthase
C5N99_11215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5N99_11220	COG0402	S-adenosylhomocysteine deaminase activity
C5N99_11235	COG1120	ATPase activity
C5N99_11240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5N99_11270	COG1509	lysine 2,3-aminomutase activity
C5N99_11275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5N99_11290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5N99_11300	COG1136	(ABC) transporter
C5N99_11305	COG1136	(ABC) transporter
C5N99_11305	COG0577	efflux transmembrane transporter activity
C5N99_11350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5N99_11380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C5N99_11390	COG1272	protein, Hemolysin III
C5N99_11395	COG0254	rRNA binding
C5N99_11400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C5N99_11405	COG1058	Belongs to the CinA family
C5N99_11405	COG1546	Belongs to the CinA family
C5N99_11415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C5N99_11420	COG0776	regulation of translation
C5N99_11425	COG0268	Binds directly to 16S ribosomal RNA
C5N99_11450	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5N99_11460	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C5N99_11470	COG0731	radical SAM domain protein
C5N99_11485	COG2201	protein-glutamate methylesterase activity
C5N99_11495	COG0835	chemotaxis
C5N99_11500	COG0643	Histidine kinase
C5N99_11500	COG2198	Histidine kinase
C5N99_11515	COG3118	belongs to the thioredoxin family
C5N99_11540	COG3833	ABC-type maltose transport systems, permease component
C5N99_11545	COG1175	transmembrane transport
C5N99_11555	COG2182	Extracellular solute-binding protein
C5N99_11560	COG1523	belongs to the glycosyl hydrolase 13 family
C5N99_11565	COG0617	tRNA 3'-terminal CCA addition
C5N99_11570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C5N99_11595	COG1301	dicarboxylic acid transport
C5N99_11610	COG1131	(ABC) transporter
C5N99_11625	COG4977	sequence-specific DNA binding
C5N99_11650	COG0601	transmembrane transport
C5N99_11655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5N99_11660	COG0444	Belongs to the ABC transporter superfamily
C5N99_11670	COG0747	negative chemotaxis
C5N99_11675	COG1418	mRNA catabolic process
C5N99_11755	COG2375	cellular response to nickel ion
C5N99_11755	COG1132	(ABC) transporter
C5N99_11765	COG1132	(ABC) transporter
C5N99_11770	COG2357	RelA SpoT domain protein
C5N99_11785	COG1131	(ABC) transporter
C5N99_11790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5N99_11795	COG0563	adenylate kinase activity
C5N99_11805	COG0772	Belongs to the SEDS family
C5N99_11810	COG0768	penicillin binding
C5N99_11825	COG1077	Cell shape determining protein MreB Mrl
C5N99_11845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5N99_11850	COG0358	DNA primase activity
C5N99_11855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5N99_11875	COG3189	MarR family transcriptional regulator
C5N99_11885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5N99_11890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C5N99_11895	COG0577	efflux transmembrane transporter activity
C5N99_11895	COG1136	(ABC) transporter
C5N99_11905	COG0318	PFAM AMP-dependent synthetase and ligase
C5N99_11910	COG0791	NLP P60 protein
C5N99_11920	COG0523	cobalamin synthesis protein
C5N99_11930	COG0297	glycogen (starch) synthase activity
C5N99_11935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5N99_11940	COG1047	Peptidyl-prolyl cis-trans
C5N99_11955	COG0251	oxidation-reduction process
C5N99_11985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C5N99_12005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5N99_12010	COG3951	Flagellar rod assembly protein muramidase FlgJ
C5N99_12020	COG4786	Flagellar basal body rod
C5N99_12030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5N99_12040	COG2226	methyltransferase
C5N99_12050	COG0596	Alpha beta hydrolase
C5N99_12070	COG1309	transcriptional regulator
C5N99_12090	COG0488	(ABC) transporter
C5N99_12105	COG1373	ATPase (AAA superfamily
C5N99_12110	COG1136	(ABC) transporter
C5N99_12115	COG1136	(ABC) transporter
C5N99_12115	COG0577	efflux transmembrane transporter activity
C5N99_12130	COG3470	protein probably involved in high-affinity Fe2 transport
C5N99_12135	COG0672	)-iron permease
C5N99_12140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5N99_12145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C5N99_12150	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C5N99_12155	COG1815	bacterial-type flagellum-dependent cell motility
C5N99_12170	COG1766	The M ring may be actively involved in energy transduction
C5N99_12180	COG1317	bacterial-type flagellum organization
C5N99_12185	COG1157	protein secretion by the type III secretion system
C5N99_12195	COG1960	acyl-CoA dehydrogenase activity
C5N99_12235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5N99_12250	COG1598	PFAM Uncharacterised protein family UPF0150
C5N99_12255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5N99_12290	COG3842	ATPase activity
C5N99_12295	COG4988	ABC transporter
C5N99_12300	COG1132	(ABC) transporter
C5N99_12315	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C5N99_12335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C5N99_12340	COG0205	6-phosphofructokinase activity
C5N99_12345	COG0285	dihydrofolate synthase activity
C5N99_12355	COG0564	pseudouridine synthase activity
C5N99_12395	COG0330	HflC and HflK could
C5N99_12400	COG0330	HflC and HflK could
C5N99_12415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5N99_12465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5N99_12475	COG3800	Transcriptional regulator
C5N99_12475	COG1396	sequence-specific DNA binding
C5N99_12510	COG1309	transcriptional regulator
C5N99_12570	COG0564	pseudouridine synthase activity
C5N99_12580	COG3735	TraB family
C5N99_12585	COG2001	Belongs to the MraZ family
C5N99_12590	COG0275	rRNA processing
C5N99_12600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5N99_12605	COG0772	Belongs to the SEDS family
C5N99_12610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5N99_12620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5N99_12650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C5N99_12660	COG2358	TRAP transporter, solute receptor (TAXI family
C5N99_12700	COG0343	queuine tRNA-ribosyltransferase activity
C5N99_12715	COG1132	(ABC) transporter
C5N99_12715	COG2375	cellular response to nickel ion
C5N99_12720	COG1132	(ABC) transporter
C5N99_12735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5N99_12735	COG0116	Belongs to the methyltransferase superfamily
C5N99_12740	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C5N99_12755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5N99_12755	COG3116	cell division
C5N99_12760	COG0084	hydrolase, TatD family'
C5N99_12770	COG1464	Belongs to the NlpA lipoprotein family
C5N99_12785	COG1477	protein flavinylation
C5N99_12795	COG3588	fructose-bisphosphate aldolase
C5N99_12815	COG1247	-acetyltransferase
C5N99_12825	COG1979	alcohol dehydrogenase
C5N99_12830	COG1994	Peptidase M50
C5N99_12840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C5N99_12850	COG0732	type I restriction modification DNA specificity domain
C5N99_12855	COG0732	type I restriction modification DNA specificity domain
C5N99_12860	COG4974	Belongs to the 'phage' integrase family
C5N99_12875	COG0732	type I restriction modification DNA specificity domain