locus-tag	class	description
FFV11_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFV11_00015	COG0592	DNA-directed DNA polymerase activity
FFV11_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FFV11_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FFV11_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFV11_00040	COG1609	Transcriptional regulator
FFV11_00055	COG1609	Transcriptional regulator
FFV11_00060	COG0072	phenylalanine-tRNA ligase activity
FFV11_00065	COG1067	ATP-dependent peptidase activity
FFV11_00075	COG1747	RNA polymerase binding
FFV11_00075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFV11_00125	COG0733	neurotransmitter:sodium symporter activity
FFV11_00140	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFV11_00150	COG1253	flavin adenine dinucleotide binding
FFV11_00155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFV11_00160	COG0459	protein refolding
FFV11_00170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FFV11_00180	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFV11_00185	COG1121	(ABC) transporter
FFV11_00190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFV11_00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFV11_00215	COG1652	LysM domain
FFV11_00225	COG0445	tRNA wobble uridine modification
FFV11_00230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFV11_00240	COG1774	PSP1 C-terminal conserved region
FFV11_00255	COG0739	heme binding
FFV11_00270	COG2890	protein-(glutamine-N5) methyltransferase activity
FFV11_00275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFV11_00285	COG3630	sodium ion export across plasma membrane
FFV11_00295	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FFV11_00300	COG0305	Participates in initiation and elongation during chromosome replication
FFV11_00310	COG0359	binds to the 23S rRNA
FFV11_00315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFV11_00320	COG0629	single-stranded DNA binding
FFV11_00325	COG0360	Binds together with S18 to 16S ribosomal RNA
FFV11_00350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FFV11_00365	COG0542	response to heat
FFV11_00375	COG1639	'signal transduction protein
FFV11_00395	COG0395	ABC-type sugar transport system, permease component
FFV11_00405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFV11_00420	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FFV11_00425	COG3604	Transcriptional regulator
FFV11_00445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFV11_00445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFV11_00445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFV11_00465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFV11_00470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FFV11_00475	COG0215	cysteine-tRNA ligase activity
FFV11_00490	COG0280	phosphate acetyltransferase
FFV11_00495	COG0457	Tetratricopeptide repeat
FFV11_00505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFV11_00510	COG0484	heat shock protein binding
FFV11_00520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFV11_00525	COG0785	Cytochrome C biogenesis protein
FFV11_00540	COG0737	Belongs to the 5'-nucleotidase family
FFV11_00545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFV11_00545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFV11_00545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFV11_00555	COG4750	Nucleotidyl transferase
FFV11_00560	COG0205	6-phosphofructokinase activity
FFV11_00590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FFV11_00595	COG3579	cysteine-type endopeptidase activity
FFV11_00600	COG0330	HflC and HflK could
FFV11_00605	COG0330	HflC and HflK could
FFV11_00610	COG0351	phosphomethylpyrimidine kinase
FFV11_00615	COG0556	nucleotide-excision repair
FFV11_00630	COG2011	ABC-type metal ion transport system permease component
FFV11_00635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFV11_00640	COG1509	lysine 2,3-aminomutase activity
FFV11_00645	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FFV11_00650	COG0457	Tetratricopeptide repeat
FFV11_00655	COG0012	GTP binding
FFV11_00660	COG0708	Exodeoxyribonuclease III
FFV11_00755	COG0569	domain protein
FFV11_00760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFV11_00765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFV11_00785	COG1022	Amp-dependent synthetase and ligase
FFV11_00805	COG1449	Belongs to the glycosyl hydrolase 57 family
FFV11_00840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FFV11_00875	COG0442	prolyl-tRNA aminoacylation
FFV11_00880	COG2255	four-way junction helicase activity
FFV11_00885	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFV11_00895	COG1121	(ABC) transporter
FFV11_00900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFV11_00905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFV11_00915	COG0588	phosphoglycerate mutase activity
FFV11_00925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFV11_00930	COG4939	FMN-binding domain protein
FFV11_00935	COG2199	diguanylate cyclase activity
FFV11_00960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FFV11_00975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFV11_00985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFV11_00990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFV11_00995	COG0051	transcription antitermination factor activity, RNA binding
FFV11_01000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFV11_01005	COG0088	Forms part of the polypeptide exit tunnel
FFV11_01010	COG0089	rRNA binding
FFV11_01015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFV11_01020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFV11_01025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFV11_01030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFV11_01035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFV11_01040	COG0255	Belongs to the universal ribosomal protein uL29 family
FFV11_01045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFV11_01050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFV11_01055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FFV11_01060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FFV11_01065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFV11_01070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FFV11_01075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFV11_01080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFV11_01085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFV11_01095	COG0200	Binds to the 23S rRNA
FFV11_01110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFV11_01115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFV11_01120	COG0202	RNA polymerase activity
FFV11_01125	COG0203	ribosomal protein L17
FFV11_01135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFV11_01140	COG0443	Heat shock 70 kDa protein
FFV11_01145	COG0484	heat shock protein binding
FFV11_01160	COG1366	Belongs to the anti-sigma-factor antagonist family
FFV11_01210	COG1122	ATPase activity
FFV11_01215	COG1268	BioY protein
FFV11_01220	COG1573	uracil-dna glycosylase
FFV11_01225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFV11_01230	COG0564	pseudouridine synthase activity
FFV11_01245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFV11_01255	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFV11_01260	COG0250	Participates in transcription elongation, termination and antitermination
FFV11_01265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFV11_01270	COG0081	regulation of translation
FFV11_01275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFV11_01280	COG0222	ribosome binding
FFV11_01285	COG0085	RNA polymerase activity
FFV11_01290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFV11_01290	COG0739	heme binding
FFV11_01295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFV11_01300	COG0049	tRNA binding
FFV11_01305	COG0714	Associated with various cellular activities
FFV11_01310	COG2304	oxidoreductase activity
FFV11_01315	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFV11_01335	COG0776	regulation of translation
FFV11_01340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFV11_01350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFV11_01355	COG0254	rRNA binding
FFV11_01360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFV11_01365	COG0584	glycerophosphoryl diester phosphodiesterase
FFV11_01390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFV11_01400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FFV11_01410	COG1114	Component of the transport system for branched-chain amino acids
FFV11_01445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFV11_01450	COG0617	tRNA 3'-terminal CCA addition
FFV11_01455	COG1475	DNA binding
FFV11_01460	COG1192	Involved in chromosome partitioning
FFV11_01485	COG0793	Belongs to the peptidase S41A family
FFV11_01495	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FFV11_01500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FFV11_01505	COG0731	radical SAM domain protein
FFV11_01515	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FFV11_01520	COG0561	phosphatase activity
FFV11_01530	COG2885	chlorophyll binding
FFV11_01535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFV11_01545	COG0237	dephospho-CoA kinase activity
FFV11_01555	COG1744	ABC transporter substrate-binding protein PnrA-like
FFV11_01560	COG3845	ABC transporter
FFV11_01565	COG4603	Belongs to the binding-protein-dependent transport system permease family
FFV11_01570	COG1079	Belongs to the binding-protein-dependent transport system permease family
FFV11_01575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FFV11_01580	COG0823	Involved in the tonB-independent uptake of proteins
FFV11_01585	COG0504	CTP synthase activity
FFV11_01590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFV11_01640	COG1744	ABC transporter substrate-binding protein PnrA-like
FFV11_01660	COG2911	Protein conserved in bacteria
FFV11_01665	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFV11_01675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FFV11_01680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FFV11_01700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFV11_01725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFV11_01740	COG0285	dihydrofolate synthase activity
FFV11_01745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFV11_01750	COG1102	Psort location Cytoplasmic, score
FFV11_01765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFV11_01790	COG1047	Peptidyl-prolyl cis-trans
FFV11_01800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFV11_01805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFV11_01810	COG4443	Transcriptional Coactivator p15 (PC4)
FFV11_01815	COG0328	RNA-DNA hybrid ribonuclease activity
FFV11_01825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFV11_01845	COG1543	Belongs to the glycosyl hydrolase 57 family
FFV11_01850	COG3330	Domain of unknown function (DUF4912)
FFV11_01865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFV11_01875	COG2198	Histidine kinase
FFV11_01875	COG0643	Histidine kinase
FFV11_01880	COG0835	chemotaxis
FFV11_01890	COG2201	protein-glutamate methylesterase activity
FFV11_01900	COG1196	nuclear chromosome segregation
FFV11_01910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFV11_01920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FFV11_01930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FFV11_01935	COG0037	tRNA processing
FFV11_01940	COG0457	Tetratricopeptide repeat
FFV11_01965	COG0653	protein targeting
FFV11_01975	COG5522	Integral membrane protein (intg_mem_TP0381)
FFV11_01980	COG2001	Belongs to the MraZ family
FFV11_01985	COG0275	rRNA processing
FFV11_01995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FFV11_02005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFV11_02015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFV11_02020	COG4974	Belongs to the 'phage' integrase family
FFV11_02030	COG0758	DNA mediated transformation
FFV11_02035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFV11_02035	COG0551	DNA topoisomerase type I activity
FFV11_02040	COG4974	Belongs to the 'phage' integrase family
FFV11_02045	COG1815	bacterial-type flagellum-dependent cell motility
FFV11_02055	COG1677	Flagellar hook-basal body complex protein FliE
FFV11_02060	COG1766	The M ring may be actively involved in energy transduction
FFV11_02070	COG1317	bacterial-type flagellum organization
FFV11_02075	COG1157	protein secretion by the type III secretion system
FFV11_02085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFV11_02095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFV11_02110	COG1862	Preprotein translocase
FFV11_02115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFV11_02120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFV11_02135	COG1115	amino acid carrier protein
FFV11_02145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFV11_02150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFV11_02155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FFV11_02160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFV11_02180	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FFV11_02190	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FFV11_02195	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FFV11_02200	COG1394	ATPase activity, coupled to movement of substances
FFV11_02205	COG1269	ATP hydrolysis coupled proton transport
FFV11_02230	COG3015	lipoprotein NlpE involved in copper resistance
FFV11_02235	COG1227	inorganic diphosphatase activity
FFV11_02245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFV11_02250	COG0835	chemotaxis
FFV11_02260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFV11_02265	COG0497	DNA recombination
FFV11_02285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FFV11_02290	COG3118	belongs to the thioredoxin family
FFV11_02295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFV11_02300	COG0457	Tetratricopeptide repeat
FFV11_02305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFV11_02315	COG2252	PERMEase
FFV11_02320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFV11_02335	COG3706	GGDEF domain
FFV11_02355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FFV11_02380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFV11_02415	COG0322	excinuclease ABC activity
FFV11_02425	COG0217	transcriptional regulatory protein
FFV11_02430	COG0166	Belongs to the GPI family
FFV11_02435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFV11_02440	COG0363	glucosamine-6-phosphate deaminase activity
FFV11_02445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFV11_02455	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
FFV11_02460	COG2982	Protein involved in outer membrane biogenesis
FFV11_02470	COG4254	PFAM FecR protein
FFV11_02490	COG0840	transmembrane signaling receptor activity
FFV11_02515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFV11_02520	COG0358	DNA primase activity
FFV11_02525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFV11_02545	COG1077	Cell shape determining protein MreB Mrl
FFV11_02560	COG0768	penicillin binding
FFV11_02565	COG0772	Belongs to the SEDS family
FFV11_02570	COG0666	response to abiotic stimulus
FFV11_02605	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFV11_02610	COG0740	serine-type endopeptidase activity
FFV11_02615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFV11_02620	COG0450	alkyl hydroperoxide reductase
FFV11_02625	COG0481	GTPase activity
FFV11_02630	COG1329	Transcriptional regulator
FFV11_02635	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFV11_02635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FFV11_02645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFV11_02655	COG0728	peptidoglycan biosynthetic process
FFV11_02660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FFV11_02670	COG2204	response regulator
FFV11_02680	COG0470	DNA polymerase III
FFV11_02685	COG1286	toxin biosynthetic process
FFV11_02690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFV11_02695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFV11_02700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFV11_02715	COG1394	ATPase activity, coupled to movement of substances
FFV11_02720	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FFV11_02725	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FFV11_02745	COG1269	ATP hydrolysis coupled proton transport
FFV11_02750	COG1527	subunit (C
FFV11_02760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFV11_02770	COG0149	triose-phosphate isomerase activity
FFV11_02775	COG0126	phosphoglycerate kinase activity
FFV11_02790	COG1366	Belongs to the anti-sigma-factor antagonist family
FFV11_02800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFV11_02805	COG0205	6-phosphofructokinase activity
FFV11_02810	COG0632	four-way junction helicase activity
FFV11_02825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFV11_02830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFV11_02850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFV11_02870	COG0628	permease
FFV11_02875	COG0546	phosphoglycolate phosphatase activity
FFV11_02885	COG2502	aspartate--ammonia ligase
FFV11_02905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FFV11_02910	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FFV11_02915	COG2089	acid synthase
FFV11_02945	COG0800	Aldolase
FFV11_02950	COG0006	proline dipeptidase activity
FFV11_02965	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FFV11_02965	COG3976	FMN-binding domain protein
FFV11_02975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFV11_02990	COG0552	protein localization to endoplasmic reticulum
FFV11_03000	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFV11_03005	COG1136	(ABC) transporter
FFV11_03020	COG4166	transmembrane transport
FFV11_03025	COG0495	leucyl-tRNA aminoacylation
FFV11_03030	COG1466	dna polymerase III delta subunit
FFV11_03035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFV11_03070	COG3064	Membrane
FFV11_03080	COG0563	adenylate kinase activity
FFV11_03085	COG0617	tRNA 3'-terminal CCA addition
FFV11_03100	COG0750	zinc metalloprotease
FFV11_03105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFV11_03110	COG0575	Belongs to the CDS family
FFV11_03115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFV11_03120	COG0233	cytoplasmic translational termination
FFV11_03125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFV11_03130	COG0052	Belongs to the universal ribosomal protein uS2 family
FFV11_03140	COG1413	lyase activity
FFV11_03145	COG0017	Asparaginyl-tRNA synthetase
FFV11_03160	COG0719	Fe-S assembly protein
FFV11_03165	COG0719	Fe-S assembly protein
FFV11_03170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFV11_03180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FFV11_03215	COG0741	lytic transglycosylase activity
FFV11_03215	COG1388	LysM domain
FFV11_03230	COG0420	3'-5' exonuclease activity
FFV11_03235	COG0419	ATPase involved in DNA repair
FFV11_03240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFV11_03255	COG2201	protein-glutamate methylesterase activity
FFV11_03260	COG0180	Tryptophanyl-tRNA synthetase
FFV11_03265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFV11_03265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFV11_03270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFV11_03280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FFV11_03310	COG3290	protein histidine kinase activity
FFV11_03310	COG0840	transmembrane signaling receptor activity
FFV11_03315	COG0840	transmembrane signaling receptor activity
FFV11_03320	COG0124	histidyl-tRNA synthetase
FFV11_03330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFV11_03335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFV11_03340	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FFV11_03350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFV11_03365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFV11_03370	COG1480	7TM receptor with intracellular HD hydrolase
FFV11_03375	COG3842	ATPase activity
FFV11_03380	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFV11_03385	COG1177	transmembrane transport
FFV11_03395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FFV11_03400	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FFV11_03420	COG0191	fructose-bisphosphate aldolase activity
FFV11_03445	COG0572	uridine kinase
FFV11_03460	COG0587	DNA-directed DNA polymerase activity
FFV11_03470	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFV11_03480	COG0423	glycine-tRNA ligase activity
FFV11_03485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFV11_03490	COG2840	Smr protein MutS2
FFV11_03495	COG3735	TraB family
FFV11_03515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFV11_03525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFV11_03530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFV11_03535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FFV11_03540	COG0142	geranyltranstransferase activity
FFV11_03550	COG1879	ABC-type sugar transport system periplasmic component
FFV11_03555	COG1129	ABC transporter
FFV11_03560	COG4211	Belongs to the binding-protein-dependent transport system permease family
FFV11_03565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFV11_03570	COG1619	proteins homologs of microcin C7 resistance protein MccF
FFV11_03575	COG1160	GTP binding
FFV11_03590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFV11_03610	COG0151	Belongs to the GarS family
FFV11_03645	COG0739	heme binding
FFV11_03650	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FFV11_03650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFV11_03660	COG0741	lytic transglycosylase activity
FFV11_03660	COG1196	nuclear chromosome segregation
FFV11_03660	COG0739	heme binding
FFV11_03675	COG1191	sigma factor activity
FFV11_03690	COG0455	bacterial-type flagellum organization
FFV11_03695	COG1419	protein localization to endoplasmic reticulum
FFV11_03700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFV11_03705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFV11_03710	COG1684	flagellar biosynthetic protein fliR
FFV11_03715	COG1987	bacterial-type flagellum assembly
FFV11_03720	COG1338	Plays a role in the flagellum-specific transport system
FFV11_03730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFV11_03730	COG1776	CheC inhibitor of MCP methylation
FFV11_03735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFV11_03740	COG1580	Controls the rotational direction of flagella during chemotaxis
FFV11_03745	COG1360	Flagellar Motor Protein
FFV11_03750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FFV11_03760	COG1749	Flagellar hook protein flgE
FFV11_03765	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFV11_03785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFV11_03795	COG0813	purine-nucleoside phosphorylase activity
FFV11_03800	COG0493	'glutamate synthase
FFV11_03805	COG0543	2 iron, 2 sulfur cluster binding
FFV11_03815	COG0799	negative regulation of ribosome biogenesis
FFV11_03830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFV11_03835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFV11_03840	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FFV11_03850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFV11_03855	COG0574	Belongs to the PEP-utilizing enzyme family
FFV11_03855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFV11_03875	COG2304	oxidoreductase activity
FFV11_03895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFV11_03900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFV11_03900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFV11_03900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFV11_03905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFV11_03910	COG0242	peptide deformylase activity
FFV11_03915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFV11_03920	COG0768	penicillin binding
FFV11_03925	COG2604	Protein of unknown function DUF115
FFV11_03930	COG2604	Protein of unknown function DUF115
FFV11_03945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFV11_03960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFV11_03975	COG1652	LysM domain
FFV11_03995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFV11_04010	COG1285	pathogenesis
FFV11_04015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FFV11_04035	COG3956	TIGRFAM MazG family protein
FFV11_04045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFV11_04045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFV11_04050	COG0739	heme binding
FFV11_04070	COG1137	ATPase activity
FFV11_04085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFV11_04100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFV11_04110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFV11_04115	COG1477	protein flavinylation
FFV11_04120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFV11_04125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFV11_04125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFV11_04130	COG1686	Belongs to the peptidase S11 family
FFV11_04135	COG0542	response to heat
FFV11_04150	COG3842	ATPase activity
FFV11_04155	COG0557	exoribonuclease II activity
FFV11_04165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFV11_04170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFV11_04175	COG0571	ribonuclease III activity
FFV11_04180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FFV11_04200	COG0492	ferredoxin-NADP+ reductase activity
FFV11_04215	COG0148	phosphopyruvate hydratase activity
FFV11_04220	COG1234	tRNA 3'-trailer cleavage
FFV11_04230	COG1464	Belongs to the NlpA lipoprotein family
FFV11_04235	COG0668	transmembrane transport
FFV11_04240	COG2033	superoxide reductase activity
FFV11_04245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFV11_04265	COG0736	holo-[acyl-carrier-protein] synthase activity
FFV11_04275	COG0101	tRNA pseudouridine synthase activity
FFV11_04280	COG0018	arginyl-trna synthetase
FFV11_04295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFV11_04310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFV11_04315	COG0488	(ABC) transporter
FFV11_04330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFV11_04340	COG0024	Methionine aminopeptidase
FFV11_04350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFV11_04355	COG1671	Belongs to the UPF0178 family
FFV11_04360	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FFV11_04370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFV11_04375	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFV11_04380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFV11_04385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFV11_04390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFV11_04395	COG0455	bacterial-type flagellum organization
FFV11_04425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFV11_04430	COG0545	Peptidyl-prolyl cis-trans isomerase
FFV11_04435	COG1104	cysteine desulfurase activity
FFV11_04440	COG3942	CHAP domain
FFV11_04440	COG1388	LysM domain
FFV11_04450	COG0606	chelatase, subunit chli
FFV11_04475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFV11_04480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFV11_04480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FFV11_04495	COG0802	atpase or kinase
FFV11_04500	COG1214	PFAM Peptidase M22, glycoprotease
FFV11_04505	COG3437	response regulator, receiver
FFV11_04505	COG2770	Histidine kinase
FFV11_04525	COG4555	ABC transporter
FFV11_04545	COG0756	dUTP diphosphatase activity
FFV11_04550	COG1185	polyribonucleotide nucleotidyltransferase activity
FFV11_04555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFV11_04565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFV11_04570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFV11_04575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFV11_04585	COG0779	Required for maturation of 30S ribosomal subunits
FFV11_04610	COG2887	Belongs to the helicase family. UvrD subfamily
FFV11_04615	COG0534	Mate efflux family protein
FFV11_04625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFV11_04635	COG0228	four-way junction DNA binding
FFV11_04640	COG1837	Belongs to the UPF0109 family
FFV11_04645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFV11_04650	COG0336	Belongs to the RNA methyltransferase TrmD family
FFV11_04655	COG0335	large ribosomal subunit rRNA binding
FFV11_04665	COG2257	FlhB HrpN YscU SpaS Family
FFV11_04675	COG0792	nuclease activity
FFV11_04695	COG2239	Acts as a magnesium transporter
FFV11_04705	COG3118	belongs to the thioredoxin family
FFV11_04710	COG0457	Tetratricopeptide repeat
FFV11_04745	COG0716	FMN binding
FFV11_04750	COG0681	Belongs to the peptidase S26 family
FFV11_04760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFV11_04765	COG2604	Protein of unknown function DUF115
FFV11_04775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFV11_04800	COG1253	flavin adenine dinucleotide binding
FFV11_04840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFV11_04845	COG0357	Ribosomal RNA small subunit methyltransferase G
FFV11_04850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFV11_04855	COG1847	R3H domain protein
FFV11_04860	COG0706	membrane insertase activity
FFV11_04865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FFV11_04875	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FFV11_04915	COG3951	Flagellar rod assembly protein muramidase FlgJ
FFV11_04925	COG4786	Flagellar basal body rod
FFV11_04935	COG0577	efflux transmembrane transporter activity
FFV11_04935	COG1136	(ABC) transporter
FFV11_04940	COG1136	(ABC) transporter
FFV11_04945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFV11_04970	COG3470	protein probably involved in high-affinity Fe2 transport
FFV11_04975	COG0672	)-iron permease
FFV11_04980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FFV11_04990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFV11_05000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFV11_05005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFV11_05010	COG0084	hydrolase, TatD family'
FFV11_05015	COG3116	cell division
FFV11_05015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFV11_05025	COG0745	RESPONSE REGULATOR receiver
FFV11_05025	COG3706	GGDEF domain
FFV11_05040	COG0326	Molecular chaperone. Has ATPase activity
FFV11_05050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFV11_05065	COG2095	MarC family integral membrane protein
FFV11_05080	COG1773	rubredoxin
FFV11_05090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFV11_05100	COG0084	hydrolase, TatD family'
FFV11_05120	COG0616	signal peptide processing
FFV11_05125	COG1115	amino acid carrier protein
FFV11_05130	COG1674	ftsk spoiiie
FFV11_05155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFV11_05160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FFV11_05165	COG0187	DNA topoisomerase II activity
FFV11_05170	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FFV11_05175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFV11_05180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFV11_05185	COG0105	UTP biosynthetic process
FFV11_05190	COG0193	aminoacyl-tRNA hydrolase activity
FFV11_05195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFV11_05200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFV11_05210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFV11_05215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFV11_05220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFV11_05230	COG1418	mRNA catabolic process
FFV11_05235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFV11_05240	COG0154	amidase activity
FFV11_05245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFV11_05250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FFV11_05255	COG2137	regulation of response to DNA damage stimulus
FFV11_05260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFV11_05265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFV11_05280	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FFV11_05285	COG0210	DNA helicase
FFV11_05290	COG0724	RNA recognition motif
FFV11_05300	COG5341	Protein conserved in bacteria
FFV11_05305	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFV11_05310	COG0530	calcium, potassium:sodium antiporter activity
FFV11_05315	COG0525	valine-tRNA ligase activity
FFV11_05325	COG1272	protein, Hemolysin III
FFV11_05330	COG0783	Belongs to the Dps family
FFV11_05335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFV11_05340	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FFV11_05345	COG0740	serine-type endopeptidase activity