locus-tag	class	description
TP_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TP_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TP_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TP_0004	ENOG4106C4Y	Protein of unknown function (DUF721)
TP_0005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP_0007	ENOG4105K95	(LipO)protein
TP_0013	ENOG4105K95	(LipO)protein
TP_0014	ENOG4106XR2	
TP_0015	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
TP_0016	ENOG4105DAN	ATP-dependent protease
TP_0019	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TP_0021	ENOG4105T73	
TP_0022	ENOG4105T73	
TP_0023	ENOG4105C8J	)-transporter
TP_0025	ENOG4107QYI	peptidase
TP_0026	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP_0029	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TP_0030	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TP_0032	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TP_0034	ENOG4105DSE	periplasmic solute binding protein
TP_0035	ENOG4105FDK	ABC transporter
TP_0036	ENOG4105FAV	ABC, transporter
TP_0037	ENOG4105C5I	Dehydrogenase
TP_0040	ENOG4108NVR	Methyl-accepting chemotaxis
TP_0042	ENOG4108WZM	domain protein
TP_0044	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TP_0045	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
TP_0046	ENOG4105MA4	psp1 domain protein
TP_0049	ENOG4105DR5	peptidase
TP_0051	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TP_0052	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TP_0053	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP_0056	ENOG4107QSA	Oxaloacetate decarboxylase
TP_0057	ENOG4105D9Q	decarboxylase (Beta subunit)
TP_0058	ENOG4105CDU	Replicative dna helicase
TP_0060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TP_0061	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TP_0062	ENOG4105Z8H	single-stranded DNA-binding protein
TP_0063	ENOG41084AY	Binds together with S18 to 16S ribosomal RNA (By similarity)
TP_0064	ENOG4106YRG	
TP_0066	ENOG4105ZFX	
TP_0068	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TP_0069	ENOG4106XJW	
TP_0070	ENOG4106D63	
TP_0071	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP_0073	ENOG4108HU6	Metal dependent phosphohydrolase
TP_0075	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
TP_0076	ENOG4105DRS	transport system, permease
TP_0078	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TP_0082	ENOG4108JUA	Transcriptional regulator
TP_0084	ENOG41077G2	
TP_0085	ENOG4105DM4	PTS System
TP_0086	ENOG4105G3C	Type iv pilus assembly
TP_0089	ENOG4105IJJ	transcriptional regulator, crp fnr family
TP_0090	ENOG4107QWW	Cell wall formation (By similarity)
TP_0091	ENOG4105C8N	cysteinyl-tRNA synthetase
TP_0092	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP_0094	ENOG4108IJ2	phosphate acetyltransferase
TP_0095	ENOG4107GWN	repeat protein
TP_0097	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TP_0098	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TP_0100	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TP_0101	ENOG4107QIV	Cytochrome c biogenesis protein
TP_0103	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TP_0104	ENOG4105CGH	5'-nucleotidase
TP_0105	ENOG4105C2M	dna polymerase I
TP_0107	ENOG4107Z36	nucleotidyl transferase
TP_0108	ENOG4105CTQ	phosphohexokinase
TP_0110	ENOG41090KZ	
TP_0111	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP_0112	ENOG4105CTZ	aminopeptidase c
TP_0113	ENOG4107RIZ	hflk protein
TP_0114	ENOG4105EPW	hflc protein
TP_0115	ENOG4105DWF	phosphomethylpyrimidine kinase
TP_0116	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TP_0118	ENOG4106V14	
TP_0119	ENOG4108UMI	ABC transporter, permease
TP_0120	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TP_0121	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TP_0122	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TP_0123	ENOG4106AHS	
TP_0124	ENOG4105C3G	gtp-binding protein
TP_0125	ENOG4105CGK	Exodeoxyribonuclease III
TP_0133	ENOG4106VGM	(LipO)protein
TP_0134	ENOG4106VGM	(LipO)protein
TP_0136	ENOG4106VGM	(LipO)protein
TP_0138	ENOG4106S4G	
TP_0139	ENOG4107ZYR	domain protein
TP_0140	ENOG4105CZN	Potassium uptake protein
TP_0141	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TP_0142	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TP_0145	ENOG4108IQE	Amp-dependent synthetase and ligase
TP_0147	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TP_0148	ENOG4106Y0N	
TP_0149	ENOG4106VF0	
TP_0150	ENOG4107AGI	
TP_0159	ENOG4106KG8	
TP_0160	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TP_0162	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TP_0163	ENOG4107SIG	periplasmic solute binding protein
TP_0164	ENOG4105DIK	(ABC) transporter
TP_0165	ENOG4107RPQ	ABC transporter
TP_0166	ENOG4107RBD	ABC, transporter
TP_0168	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TP_0170	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TP_0171	ENOG41088B0	Major membrane immunogen
TP_0174	ENOG41090QV	Protein of unknown function DUF115
TP_0175	ENOG41090QV	Protein of unknown function DUF115
TP_0177	ENOG4105X4X	Protein of unknown function DUF115
TP_0179	ENOG410698I	
TP_0181	ENOG4106U5D	Septum formation initiator
TP_0183	ENOG4106QD2	
TP_0184	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TP_0185	ENOG4105C3F	Signal peptidase i
TP_0186	ENOG4105CSA	Coproporphyrinogen iii oxidase
TP_0187	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TP_0188	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TP_0189	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TP_0190	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TP_0191	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TP_0192	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TP_0193	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TP_0194	ENOG41082G4	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TP_0195	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TP_0196	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TP_0198	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TP_0199	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TP_0200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TP_0201	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TP_0202	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TP_0203	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TP_0204	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TP_0205	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TP_0206	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TP_0207	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TP_0208	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TP_0209	ENOG41067V7	50S ribosomal protein L36
TP_0210	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TP_0211	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TP_0212	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP_0213	ENOG4108ZT0	50S ribosomal protein l17
TP_0214	ENOG4106DC9	
TP_0215	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TP_0216	ENOG4105CFG	Acts as a chaperone (By similarity)
TP_0220	ENOG4105WN5	stage II sporulation protein
TP_0227	ENOG4108JJB	ABC transporter
TP_0228	ENOG4105VKD	bioY protein
TP_0229	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TP_0230	ENOG4105C25	Primosomal protein n'
TP_0231	ENOG4105EI2	Pseudouridine synthase
TP_0234	ENOG41084ED	50S ribosomal protein L33
TP_0236	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TP_0237	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TP_0238	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TP_0239	ENOG4108VZM	50s ribosomal protein L10
TP_0240	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TP_0241	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP_0242	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TP_0243	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TP_0244	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TP_0247	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TP_0248	ENOG4106UC9	
TP_0249	ENOG4107NGC	Flagellar filament outer layer protein
TP_0251	ENOG41083IJ	DNA-binding protein
TP_0252	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TP_0254	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TP_0255	ENOG41082DI	50s ribosomal protein l31
TP_0256	ENOG41081GK	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase
TP_0257	ENOG4107YU0	Glycerophosphoryl diester phosphodiesterase family
TP_0260	ENOG4105I76	(LipO)protein
TP_0262	ENOG4105IJJ	transcriptional regulator, crp fnr family
TP_0264	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TP_0269	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TP_0270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TP_0271	ENOG4105FA0	parb-like partition protein
TP_0272	ENOG4107QJE	Chromosome Partitioning Protein
TP_0277	ENOG4105CN1	protease
TP_0279	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TP_0282	ENOG4105W0I	repeat-containing protein
TP_0283	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TP_0285	ENOG4108ZVA	radical SAM domain protein
TP_0288	ENOG4107TY6	Acylneuraminate cytidylyltransferase
TP_0290	ENOG4108HCJ	Hydrolase
TP_0292	ENOG4107QKZ	Ompa motb domain protein
TP_0294	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TP_0296	ENOG41083NY	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TP_0298	ENOG4108SSC	basic membrane
TP_0301	ENOG4108TWB	ABC transporter (Permease
TP_0302	ENOG4108ZV0	ABC transporter, permease
TP_0303	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TP_0304	ENOG4105MB2	
TP_0305	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TP_0306	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TP_0308	ENOG4105E89	ABC transporter
TP_0319	ENOG4107TFB	basic membrane
TP_0321	ENOG4108JQ9	ABC transporter
TP_0322	ENOG4105UIB	(ABC) transporter
TP_0326	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TP_0328	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TP_0329	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TP_0331	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TP_0337	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TP_0340	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TP_0341	ENOG4105DFU	Cell wall formation (By similarity)
TP_0342	ENOG4108Z4J	Cytidine monophosphate kinase
TP_0344	ENOG4108JA2	transcriptioN-repair coupling factor
TP_0345	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TP_0349	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TP_0350	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TP_0351	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TP_0352	ENOG4105VEM	Conserved domain protein
TP_0353	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TP_0354	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TP_0357	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TP_0358	ENOG4107RFW	hydrolase family 57
TP_0359	ENOG4106ARS	
TP_0362	ENOG41084P6	50S ribosomal protein l28
TP_0363	ENOG4105CBS	Chea signal transduction histidine kinase
TP_0364	ENOG4105YFD	chemotaxis, protein
TP_0366	ENOG4107Z9R	response regulator
TP_0367	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TP_0369	ENOG4106GEY	
TP_0371	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TP_0372	ENOG4107TVT	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TP_0373	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TP_0374	ENOG41069X2	
TP_0376	ENOG4107I03	
TP_0379	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TP_0381	ENOG410615F	Integral membrane protein (intg_mem_TP0381)
TP_0383	ENOG4107YM1	mraZ protein
TP_0384	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TP_0386	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TP_0387	ENOG4105CNI	cell division protein FtsW
TP_0388	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
TP_0389	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TP_0390	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TP_0391	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP_0393	ENOG4105C79	DNA protecting protein DprA
TP_0394	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TP_0395	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TP_0396	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TP_0397	ENOG4108ZC9	flagellar basal-body rod protein flgc
TP_0398	ENOG41069WH	flagellar hook-basal body complex
TP_0399	ENOG4107U2N	Flagellar M-ring protein
TP_0400	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP_0401	ENOG4105W2B	Flagellar assembly protein
TP_0402	ENOG4108JIR	Flagellum-specific ATP synthase
TP_0404	ENOG4108346	Beta-lactamase domain protein
TP_0406	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TP_0410	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP_0411	ENOG4107XHD	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TP_0414	ENOG4105BZG	amino acid carrier protein
TP_0417	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TP_0418	ENOG41080VC	Galactokinase (EC 2.7.1.6)
TP_0419	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TP_0422	ENOG4106R77	
TP_0424	ENOG4108RY1	ATP synthase, subunit E
TP_0426	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TP_0427	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TP_0428	ENOG4108WBK	V-type ATP synthase subunit D
TP_0429	ENOG4107U1W	v-type ATP synthase subunit I
TP_0431	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TP_0436	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
TP_0437	ENOG41068FD	
TP_0438	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TP_0439	ENOG4105YFD	chemotaxis, protein
TP_0441	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TP_0442	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TP_0446	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TP_0447	ENOG4106B9X	
TP_0448	ENOG4107V28	uracil phosphoribosyltransferase
TP_0449	ENOG4106VIZ	
TP_0450	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TP_0452	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TP_0453	ENOG41071ED	
TP_0454	ENOG4106UUF	
TP_0456	ENOG4106U6F	
TP_0458	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TP_0459	ENOG4105FE9	pseudouridine synthase
TP_0462	ENOG4106VGM	(LipO)protein
TP_0463	ENOG4106VGM	(LipO)protein
TP_0464	ENOG4107W7Y	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TP_0466	ENOG41090Q2	
TP_0472	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TP_0474	ENOG4105CDY	transcriptional regulatory protein
TP_0475	ENOG4107QP8	phosphohexose isomerase
TP_0476	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
TP_0477	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
TP_0478	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TP_0480	ENOG4105RJI	
TP_0481	ENOG410877G	
TP_0484	ENOG4105J3I	
TP_0485	ENOG4105F8J	Adenylate Guanylate cyclase
TP_0487	ENOG4107GGS	
TP_0488	ENOG4105C8Q	Methyl-accepting chemotaxis
TP_0491	ENOG4105HHA	aminodeoxychorismate lyase
TP_0492	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TP_0493	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP_0497	ENOG4105DFF	Rod shape-determining protein mreb
TP_0500	ENOG4105CJN	penicillin-binding protein
TP_0501	ENOG4105CNI	cell division protein FtsW
TP_0502	ENOG41082BE	ankyrin repeat-containing protein
TP_0503	ENOG4105ZF0	Lipoprotein
TP_0506	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TP_0507	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TP_0508	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TP_0509	ENOG4105D3R	alkyl hydroperoxide reductase
TP_0510	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TP_0511	ENOG4108VJ1	Transcriptional regulator (CarD family
TP_0512	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TP_0514	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TP_0516	ENOG4105CJR	Integral membrane protein (MviN
TP_0517	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TP_0519	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TP_0521	ENOG4107QRG	dna polymerase iii
TP_0522	ENOG4107JR8	Colicin v production protein
TP_0523	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TP_0524	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TP_0525	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TP_0526	ENOG4105CQ7	ATP-dependent helicase
TP_0527	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TP_0528	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TP_0529	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TP_0533	ENOG4107WUB	V-type ATPase 116 kDa subunit
TP_0536	ENOG4106447	Preprotein translocase subunit SecG
TP_0537	ENOG4105CP7	Triose-phosphate isomerase
TP_0538	ENOG4105BZA	Phosphoglycerate kinase
TP_0540	ENOG4105WN5	stage II sporulation protein
TP_0541	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TP_0542	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
TP_0543	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TP_0546	ENOG4105C0H	protease
TP_0547	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TP_0548	ENOG4106J2Q	Uncharacterised protein family (UPF0164)
TP_0549	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP_0550	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TP_0552	ENOG41062VP	
TP_0553	ENOG4105F4G	Membrane
TP_0554	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TP_0556	ENOG4105CU9	asparagine synthetase A
TP_0559	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TP_0560	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TP_0561	ENOG4105HA9	of methanol dehydrogenase type
TP_0564	ENOG4106JH4	
TP_0566	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
TP_0568	ENOG4108UHU	Aldolase
TP_0569	ENOG4105DC7	peptidase M24
TP_0572	ENOG4105I7V	membrAne
TP_0574	ENOG4107TXU	
TP_0576	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TP_0577	ENOG4106MPK	
TP_0578	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TP_0579	ENOG410774Y	
TP_0580	ENOG4105D60	lipoprotein releasing system transmembrane protein
TP_0581	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TP_0584	ENOG4105G9E	
TP_0586	ENOG4105C8T	Leucyl-tRNA synthetase
TP_0589	ENOG4105KZ7	phosphocarrier protein hpr
TP_0591	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TP_0593	ENOG4106TP1	
TP_0595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TP_0596	ENOG4105DJ0	Poly(A) Polymerase
TP_0598	ENOG4105X1A	
TP_0599	ENOG41062Z1	
TP_0600	ENOG4105DZP	Membrane-associated zinc metalloprotease
TP_0601	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TP_0603	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TP_0604	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TP_0605	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TP_0606	ENOG4105CE9	30S ribosomal protein S2
TP_0608	ENOG4105SXG	
TP_0609	ENOG4105C5S	asparaginyl-tRNA synthetase
TP_0612	ENOG4105DIW	FeS assembly protein SUFB
TP_0614	ENOG4105C9B	Cysteine desulfurase
TP_0616	ENOG4105E66	phosphoriboisomerase A
TP_0623	ENOG4105E9H	Lytic Murein transglycosylase
TP_0625	ENOG4106XHX	
TP_0626	ENOG4107RFY	SbcCD D subunit
TP_0627	ENOG4105EYH	Exonuclease
TP_0628	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TP_0629	ENOG4106URY	
TP_0630	ENOG4105BZU	Histidine kinase
TP_0631	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TP_0632	ENOG4105C31	Tryptophanyl-tRNA synthetase
TP_0633	ENOG4105E0X	reductase
TP_0634	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TP_0637	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TP_0638	ENOG41071ZZ	
TP_0639	ENOG4105C8Q	Methyl-accepting chemotaxis
TP_0641	ENOG4105CUT	histidyl-tRNA synthetase
TP_0643	ENOG4108JDX	DNA polymerase iii, epsilon subunit
TP_0644	ENOG4105DK7	lysyl-tRNA synthetase
TP_0647	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TP_0649	ENOG4105C37	(CBS) domain
TP_0650	ENOG41082QW	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TP_0651	ENOG4105CTJ	Metal Dependent Phosphohydrolase
TP_0652	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TP_0653	ENOG4105F38	ABC transporter, permease
TP_0654	ENOG4105D38	putrescine abc transporter
TP_0655	ENOG4108HM4	ABC transporter
TP_0657	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TP_0658	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
TP_0661	ENOG41069DF	
TP_0662	ENOG4105D2N	Aldolase
TP_0665	ENOG4105JTB	
TP_0666	ENOG4106FRC	
TP_0667	ENOG4105DBI	uridine monophosphokinase
TP_0669	ENOG4105C0B	DNA polymerase III (alpha subunit)
TP_0670	ENOG4105CPF	Cell wall formation (By similarity)
TP_0672	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TP_0673	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TP_0674	ENOG4105XAB	Smr domain protein
TP_0675	ENOG4105MBR	gumn family
TP_0677	ENOG4105Z8J	
TP_0678	ENOG41089XN	
TP_0680	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TP_0681	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TP_0682	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TP_0683	ENOG4105EAH	synthase
TP_0684	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
TP_0685	ENOG4105C2J	ABC transporter
TP_0686	ENOG4107R2W	ABC transporter, permease
TP_0687	ENOG4105CB5	ATP-dependent DNA helicase recG
TP_0688	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
TP_0689	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TP_0690	ENOG410750H	
TP_0692	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TP_0693	ENOG4106GZE	
TP_0695	ENOG4105C12	Phosphoribosylglycinamide synthetase
TP_0700	ENOG4106AG2	
TP_0701	ENOG41068UM	RNA Polymerase
TP_0702	ENOG4105DR5	peptidase
TP_0704	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TP_0705	ENOG4108JQC	penicillin-binding protein 1A
TP_0706	ENOG4105E4C	Lytic transglycosylase catalytic
TP_0709	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP_0711	ENOG4106FP0	
TP_0713	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TP_0714	ENOG4105D7B	Flagellar biosynthesis protein flha
TP_0715	ENOG4105D00	flagellar biosynthetic protein flhB
TP_0716	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TP_0717	ENOG4105VS8	Flagellar biosynthetic protein fliq
TP_0718	ENOG4105CN7	Flagellar biosynthetic protein FliP
TP_0720	ENOG4105DD5	Flagellar motor switch protein
TP_0721	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TP_0722	ENOG41064SM	flagellar basal body-associated protein flil
TP_0724	ENOG4107XSU	flagellar motor protein motb
TP_0725	ENOG4107R0U	MotA TolQ exbB proton channel
TP_0727	ENOG4105BZE	flagellar hook protein, FlgE
TP_0728	ENOG410822I	Flagellar hook capping protein
TP_0732	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TP_0733	ENOG4105XBK	
TP_0734	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TP_0735	ENOG4105BZ8	glutamate synthase
TP_0736	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TP_0738	ENOG4107ZFZ	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TP_0741	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TP_0742	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TP_0743	ENOG4105K46	50S ribosomal protein l27
TP_0745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TP_0746	ENOG4107QJD	pyruvate phosphate dikinase
TP_0747	ENOG4108SXE	
TP_0748	ENOG41073RW	Cytoplasmic filament protein A
TP_0750	ENOG4105YQK	von Willebrand factor type A domain
TP_0751	ENOG4106BN6	
TP_0752	ENOG41073FS	
TP_0754	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TP_0755	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TP_0756	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TP_0757	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TP_0758	ENOG41084YP	30S ribosomal protein S21
TP_0760	ENOG4105CJN	penicillin-binding protein
TP_0762	ENOG4107YZD	Protein of unknown function DUF115
TP_0763	ENOG41063XV	
TP_0765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TP_0767	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TP_0768	ENOG4106UV5	membrane protein A
TP_0769	ENOG4108I7Y	domain protein
TP_0770	ENOG4105C1J	atp-dependent rna helicase
TP_0771	ENOG4105EAM	Na Pi-cotransporter
TP_0772	ENOG4106S0F	
TP_0773	ENOG4105C0H	protease
TP_0774	ENOG4105KT7	mgtC SapB transporter
TP_0775	ENOG4105CSM	endonuclease III
TP_0777	ENOG4106XCQ	Inherit from COG: Pfam:DUF82
TP_0778	ENOG4105DXN	mazG family
TP_0779	ENOG41083CW	dedA protein
TP_0780	ENOG4107QMG	Nad synthetase
TP_0783	ENOG410684W	
TP_0784	ENOG4106X59	Pfam:DUF1239
TP_0786	ENOG4108IUZ	ABC transporter
TP_0788	ENOG41061XC	
TP_0789	ENOG4108M1M	outer membrane lipoprotein-sorting protein
TP_0792	ENOG4105I03	Flagellin
TP_0793	ENOG4106N2C	
TP_0794	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TP_0796	ENOG4105CJ2	(LipO)protein
TP_0797	ENOG4105II7	pyrroline-5-carboxylate reductase
TP_0798	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TP_0800	ENOG4105DZ1	carboxypeptidase
TP_0801	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TP_0807	ENOG41085D1	50S ribosomal protein L32
TP_0808	ENOG41084E5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TP_0809	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TP_0810	ENOG4107R5S	dna adenine
TP_0813	ENOG41090QR	
TP_0814	ENOG4105C3M	thioredoxin reductase
TP_0816	ENOG4106TEA	
TP_0817	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TP_0819	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TP_0821	ENOG4105D01	(LipO)protein
TP_0823	ENOG4105MAX	Superoxide reductase
TP_0824	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TP_0828	ENOG41083V3	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TP_0829	ENOG4108CER	Uncharacterized protein conserved in bacteria (DUF2225)
TP_0830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TP_0831	ENOG4105C75	arginyL-tRNA synthetase
TP_0834	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TP_0836	ENOG4105VVB	
TP_0837	ENOG4105C22	threonyL-tRNA synthetase
TP_0838	ENOG4105C5H	ABC transporter
TP_0841	ENOG4105C0H	protease
TP_0842	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TP_0843	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TP_0844	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TP_0845	ENOG41082MQ	UPF0178 protein
TP_0846	ENOG4106BMT	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TP_0847	ENOG4106BH8	
TP_0848	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TP_0849	ENOG41084MZ	50S ribosomal protein L35
TP_0850	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TP_0851	ENOG4105HCZ	
TP_0852	ENOG4107WGG	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TP_0853	ENOG4107R21	site-determining protein
TP_0855	ENOG4106NKH	
TP_0861	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TP_0862	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TP_0863	ENOG4107QI6	Cysteine desulfurase
TP_0864	ENOG41068JE	domain protein
TP_0868	ENOG4105I03	Flagellin
TP_0870	ENOG4105I03	Flagellin
TP_0872	ENOG4107VE5	flagellar hook-associated protein
TP_0873	ENOG4106SAP	
TP_0875	ENOG4105K8N	protein family UPF0079, ATPase
TP_0876	ENOG41072GX	Peptidase M22 Glycoprotease
TP_0877	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TP_0878	ENOG4106QPK	
TP_0881	ENOG4108IUW	ABC transporter
TP_0885	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TP_0886	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TP_0887	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TP_0889	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TP_0890	ENOG41080JB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TP_0891	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TP_0892	ENOG4105CHV	Transcription elongation factor NusA
TP_0893	ENOG410854D	Required for maturation of 30S ribosomal subunits (By similarity)
TP_0900	ENOG4109031	
TP_0901	ENOG4107QMU	Mate efflux family protein
TP_0903	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TP_0905	ENOG4105K5M	30s ribosomal protein S16
TP_0906	ENOG4105VB6	UPF0109 protein
TP_0907	ENOG4107GQ3	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TP_0908	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TP_0909	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TP_0911	ENOG4105VM1	flagellar
TP_0912	ENOG4105CPI	Metal Dependent Phosphohydrolase
TP_0913	ENOG41082I4	UPF0102 protein
TP_0917	ENOG4105CJW	magnesium transporter
TP_0919	ENOG4105K63	Thioredoxin
TP_0920	ENOG4108QUE	repeat-containing protein
TP_0925	ENOG4108Z29	Flavodoxin
TP_0926	ENOG4105C3F	Signal peptidase i
TP_0928	ENOG4108W50	ppic-type peptidyL-prolyl cis-trans isomerase
TP_0930	ENOG4106SUR	Protein of unknown function DUF115
TP_0931	ENOG4107MD5	glycoside hydrolase, family
TP_0933	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TP_0938	ENOG4106W1H	
TP_0939	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TP_0941	ENOG4106RHC	
TP_0942	ENOG4106VWR	
TP_0945	ENOG4105DJV	ribulose-phosphate 3-epimerase
TP_0946	ENOG41083HS	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TP_0947	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TP_0949	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TP_0951	ENOG4105VG0	50S ribosomal protein l34
TP_0956	ENOG41081IW	Inherit from COG: Membrane
TP_0958	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TP_0959	ENOG410680E	Flagellar protein
TP_0960	ENOG4105CGA	flagellar basal-body rod protein FlgG
TP_0961	ENOG4105CGA	flagellar basal-body rod protein FlgG
TP_0963	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP_0964	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TP_0965	ENOG410624X	efflux transporter, rnd family, mfp subunit
TP_0966	ENOG4106KIQ	
TP_0967	ENOG4106KIQ	
TP_0971	ENOG4108SDV	Periplasmic Protein
TP_0972	ENOG4107SJW	iron permease, FTR1
TP_0973	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TP_0974	ENOG4105ZAM	anti-sigma-28 factor flgm family protein
TP_0975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TP_0976	ENOG4106WPJ	
TP_0977	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TP_0978	ENOG410835P	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TP_0979	ENOG4105F8V	Hydrolase, tatD family
TP_0980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TP_0981	ENOG4105BZU	Histidine kinase
TP_0983	ENOG4105Y6R	
TP_0984	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TP_0985	ENOG4105C9M	aspartyl-trna synthetase
TP_0988	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
TP_0991	ENOG4105VCQ	rubredoxin
TP_0993	ENOG4105K6T	rare lipoprotein A
TP_0994	ENOG4105F8V	Hydrolase, tatD family
TP_0997	ENOG4105D07	Signal peptide peptidase, SppA
TP_0998	ENOG4105BZG	amino acid carrier protein
TP_0999	ENOG4105CNU	cell division protein FtsK
TP_1001	ENOG4105TQV	
TP_1003	ENOG4106SWD	
TP_1004	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TP_1005	ENOG4105C6E	dna polymerase iii
TP_1006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TP_1007	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TP_1008	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TP_1009	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TP_1010	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TP_1011	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TP_1012	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TP_1013	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TP_1014	ENOG4106JWJ	
TP_1015	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TP_1016	ENOG4107Z25	Basic membrane protein
TP_1017	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TP_1018	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TP_1019	ENOG4107I15	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TP_1020	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TP_1021	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TP_1022	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TP_1023	ENOG410691R	Modulates RecA activity (By similarity)
TP_1024	ENOG4108UJD	30S ribosomal protein S9
TP_1025	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TP_1027	ENOG4108I5U	Uridine phosphorylase
TP_1028	ENOG4105C4R	Atp-dependent dna helicase
TP_1029	ENOG41062BZ	domain protein
TP_1032	ENOG41085BT	Protein of unknown function (DUF1312)
TP_1033	ENOG4105D78	K07001 NTE family protein
TP_1034	ENOG4105FEU	K -dependent Na -Ca exchanger
TP_1035	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TP_1037	ENOG4108UT2	hemolysin iii
TP_1038	ENOG4108RMU	ferritin dps family protein
TP_1039	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TP_1040	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TP_1041	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)