locus-tag	class	description
TPSea814_000002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TPSea814_000003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TPSea814_0000037	ENOG4105C5I	Dehydrogenase
TPSea814_000004	ENOG4106C4Y	Protein of unknown function (DUF721)
TPSea814_000005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TPSea814_000007	ENOG4105K95	(LipO)protein
TPSea814_000013	ENOG4105K95	(LipO)protein
TPSea814_0000133	ENOG4106VGM	(LipO)protein
TPSea814_0000134	ENOG4106VGM	(LipO)protein
TPSea814_000015	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
TPSea814_000016	ENOG4105DAN	ATP-dependent protease
TPSea814_000021	ENOG4105T73	
TPSea814_000022	ENOG4105T73	
TPSea814_000023	ENOG4105C8J	)-transporter
TPSea814_000025	ENOG4107QYI	peptidase
TPSea814_000026	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPSea814_000029	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TPSea814_000030	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TPSea814_000032	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TPSea814_000034	ENOG4105DSE	periplasmic solute binding protein
TPSea814_000035	ENOG4105FDK	ABC transporter
TPSea814_000036	ENOG4105FAV	ABC, transporter
TPSea814_000040	ENOG4108NVR	Methyl-accepting chemotaxis
TPSea814_000042	ENOG4108WZM	domain protein
TPSea814_000044	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TPSea814_000045	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
TPSea814_000046	ENOG4105MA4	psp1 domain protein
TPSea814_000049	ENOG4105DR5	peptidase
TPSea814_000052	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TPSea814_000053	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TPSea814_000056	ENOG4107QSA	Oxaloacetate decarboxylase
TPSea814_000057	ENOG4105D9Q	decarboxylase (Beta subunit)
TPSea814_000058	ENOG4105CDU	Replicative dna helicase
TPSea814_000060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TPSea814_000061	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TPSea814_000062	ENOG4105Z8H	single-stranded DNA-binding protein
TPSea814_000063	ENOG41084AY	Binds together with S18 to 16S ribosomal RNA (By similarity)
TPSea814_000064	ENOG4106YRG	
TPSea814_000066	ENOG4105ZFX	
TPSea814_000068	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TPSea814_000069	ENOG4106XJW	
TPSea814_000070	ENOG4106D63	
TPSea814_000071	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPSea814_000073	ENOG4108HU6	Metal dependent phosphohydrolase
TPSea814_000075	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
TPSea814_000076	ENOG4105DRS	transport system, permease
TPSea814_000078	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TPSea814_000082	ENOG4108JUA	Transcriptional regulator
TPSea814_000084	ENOG41077G2	
TPSea814_000085	ENOG4105DM4	PTS System
TPSea814_000086	ENOG4105G3C	Type iv pilus assembly
TPSea814_000089	ENOG4105IJJ	transcriptional regulator, crp fnr family
TPSea814_000090	ENOG4107QWW	Cell wall formation (By similarity)
TPSea814_000091	ENOG4105C8N	cysteinyl-tRNA synthetase
TPSea814_000092	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPSea814_000094	ENOG4108IJ2	phosphate acetyltransferase
TPSea814_000095	ENOG4107GWN	repeat protein
TPSea814_000097	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TPSea814_000098	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPSea814_000100	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TPSea814_000101	ENOG4107QIV	Cytochrome c biogenesis protein
TPSea814_000103	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TPSea814_000104	ENOG4105CGH	5'-nucleotidase
TPSea814_000105	ENOG4105C2M	dna polymerase I
TPSea814_000108	ENOG4105CTQ	phosphohexokinase
TPSea814_000110	ENOG41090KZ	
TPSea814_000111	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPSea814_000113	ENOG4107RIZ	hflk protein
TPSea814_000114	ENOG4105EPW	hflc protein
TPSea814_000115	ENOG4105DWF	phosphomethylpyrimidine kinase
TPSea814_000116	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TPSea814_000118	ENOG4106V14	
TPSea814_000119	ENOG4108UMI	ABC transporter, permease
TPSea814_000120	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TPSea814_000121	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TPSea814_000122	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TPSea814_000124	ENOG4105C3G	gtp-binding protein
TPSea814_000125	ENOG4105CGK	Exodeoxyribonuclease III
TPSea814_000136	ENOG4106VGM	(LipO)protein
TPSea814_000138	ENOG4106S4G	
TPSea814_000139	ENOG4107ZYR	domain protein
TPSea814_000140	ENOG4105CZN	Potassium uptake protein
TPSea814_000141	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TPSea814_000142	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TPSea814_000145	ENOG4108IQE	Amp-dependent synthetase and ligase
TPSea814_000147	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TPSea814_000148	ENOG4106Y0N	
TPSea814_000149	ENOG4106VF0	
TPSea814_000150	ENOG4107AGI	
TPSea814_000159	ENOG4106KG8	
TPSea814_000160	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TPSea814_000162	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TPSea814_000163	ENOG4107SIG	periplasmic solute binding protein
TPSea814_000164	ENOG4105DIK	(ABC) transporter
TPSea814_000165	ENOG4107RPQ	ABC transporter
TPSea814_000166	ENOG4107RBD	ABC, transporter
TPSea814_000168	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TPSea814_000170	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TPSea814_000171	ENOG41088B0	Major membrane immunogen
TPSea814_000175	ENOG41090QV	Protein of unknown function DUF115
TPSea814_000177	ENOG4105X4X	Protein of unknown function DUF115
TPSea814_000179	ENOG410698I	
TPSea814_000180	ENOG4106U5D	Septum formation initiator
TPSea814_000183	ENOG4106QD2	
TPSea814_000184	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TPSea814_000185	ENOG4105C3F	Signal peptidase i
TPSea814_000186	ENOG4105CSA	Coproporphyrinogen iii oxidase
TPSea814_000187	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TPSea814_000188	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TPSea814_000189	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TPSea814_000190	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TPSea814_000191	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TPSea814_000192	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TPSea814_000193	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TPSea814_000194	ENOG41082G4	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TPSea814_000195	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TPSea814_000196	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TPSea814_000198	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TPSea814_000199	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TPSea814_000200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TPSea814_000201	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TPSea814_000202	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TPSea814_000203	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TPSea814_000204	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TPSea814_000205	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TPSea814_000206	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TPSea814_000207	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TPSea814_000208	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TPSea814_000209	ENOG41067V7	50S ribosomal protein L36
TPSea814_000210	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TPSea814_000211	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TPSea814_000212	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPSea814_000213	ENOG4108ZT0	50S ribosomal protein l17
TPSea814_000214	ENOG4106DC9	
TPSea814_000215	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TPSea814_000216	ENOG4105CFG	Acts as a chaperone (By similarity)
TPSea814_000217	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPSea814_000220	ENOG4105WN5	stage II sporulation protein
TPSea814_000227	ENOG4108JJB	ABC transporter
TPSea814_000228	ENOG4105VKD	bioY protein
TPSea814_000229	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TPSea814_000230	ENOG4105C25	Primosomal protein n'
TPSea814_000231	ENOG4105EI2	Pseudouridine synthase
TPSea814_000234	ENOG41084ED	50S ribosomal protein L33
TPSea814_000236	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TPSea814_000237	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TPSea814_000238	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TPSea814_000239	ENOG4108VZM	50s ribosomal protein L10
TPSea814_000240	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TPSea814_000241	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPSea814_000242	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPSea814_000243	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TPSea814_000244	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TPSea814_000247	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TPSea814_000248	ENOG4106UC9	
TPSea814_000249	ENOG4107NGC	Flagellar filament outer layer protein
TPSea814_000250	ENOG41083IJ	DNA-binding protein
TPSea814_000252	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TPSea814_000254	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TPSea814_000255	ENOG41082DI	50s ribosomal protein l31
TPSea814_000256	ENOG41081GK	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase
TPSea814_000257	ENOG4107YU0	Glycerophosphoryl diester phosphodiesterase family
TPSea814_000260	ENOG4105I76	(LipO)protein
TPSea814_000262	ENOG4105IJJ	transcriptional regulator, crp fnr family
TPSea814_000264	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TPSea814_000269	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TPSea814_000270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TPSea814_000271	ENOG4105FA0	parb-like partition protein
TPSea814_000272	ENOG4107QJE	Chromosome Partitioning Protein
TPSea814_000277	ENOG4105CN1	protease
TPSea814_000279	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TPSea814_000282	ENOG4105W0I	repeat-containing protein
TPSea814_000283	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TPSea814_000284	ENOG4108ZVA	radical SAM domain protein
TPSea814_000288	ENOG4107TY6	Acylneuraminate cytidylyltransferase
TPSea814_000290	ENOG4108HCJ	Hydrolase
TPSea814_000292	ENOG4107QKZ	Ompa motb domain protein
TPSea814_000294	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TPSea814_000296	ENOG41083NY	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TPSea814_000298	ENOG4108SSC	basic membrane
TPSea814_000301	ENOG4108TWB	ABC transporter (Permease
TPSea814_000302	ENOG4108ZV0	ABC transporter, permease
TPSea814_000303	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TPSea814_000304	ENOG4105MB2	
TPSea814_000305	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TPSea814_000306	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TPSea814_000308	ENOG4105E89	ABC transporter
TPSea814_000319	ENOG4107TFB	basic membrane
TPSea814_000321	ENOG4108JQ9	ABC transporter
TPSea814_000322	ENOG4105UIB	(ABC) transporter
TPSea814_000326	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TPSea814_000328	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TPSea814_000329	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TPSea814_000331	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TPSea814_000337	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TPSea814_000340	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TPSea814_000341	ENOG4105DFU	Cell wall formation (By similarity)
TPSea814_000342	ENOG4108Z4J	Cytidine monophosphate kinase
TPSea814_000344	ENOG4108JA2	transcriptioN-repair coupling factor
TPSea814_000345	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TPSea814_000349	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TPSea814_000350	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TPSea814_000351	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TPSea814_000352	ENOG4105VEM	Conserved domain protein
TPSea814_000353	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TPSea814_000354	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TPSea814_000357	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TPSea814_000358	ENOG4107RFW	hydrolase family 57
TPSea814_000359	ENOG4106ARS	
TPSea814_000362	ENOG41084P6	50S ribosomal protein l28
TPSea814_000363	ENOG4105CBS	Chea signal transduction histidine kinase
TPSea814_000364	ENOG4105YFD	chemotaxis, protein
TPSea814_000366	ENOG4107Z9R	response regulator
TPSea814_000367	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TPSea814_000371	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TPSea814_000372	ENOG4107TVT	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TPSea814_000373	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TPSea814_000374	ENOG41069X2	
TPSea814_000376	ENOG4107I03	
TPSea814_000379	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TPSea814_000381	ENOG410615F	Integral membrane protein (intg_mem_TP0381)
TPSea814_000383	ENOG4107YM1	mraZ protein
TPSea814_000384	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TPSea814_000386	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TPSea814_000387	ENOG4105CNI	cell division protein FtsW
TPSea814_000388	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
TPSea814_000389	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TPSea814_000390	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TPSea814_000391	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TPSea814_000393	ENOG4105C79	DNA protecting protein DprA
TPSea814_000394	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TPSea814_000396	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TPSea814_000397	ENOG4108ZC9	flagellar basal-body rod protein flgc
TPSea814_000398	ENOG41069WH	flagellar hook-basal body complex
TPSea814_000400	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPSea814_000401	ENOG4105W2B	Flagellar assembly protein
TPSea814_000402	ENOG4108JIR	Flagellum-specific ATP synthase
TPSea814_000404	ENOG4108346	Beta-lactamase domain protein
TPSea814_000406	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TPSea814_000410	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TPSea814_000411	ENOG4107XHD	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TPSea814_000414	ENOG4105BZG	amino acid carrier protein
TPSea814_000417	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TPSea814_000418	ENOG41080VC	Galactokinase (EC 2.7.1.6)
TPSea814_000419	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TPSea814_000422	ENOG4106R77	
TPSea814_000424	ENOG4108RY1	ATP synthase, subunit E
TPSea814_000426	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TPSea814_000427	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TPSea814_000428	ENOG4108WBK	V-type ATP synthase subunit D
TPSea814_000429	ENOG4107U1W	v-type ATP synthase subunit I
TPSea814_000431	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TPSea814_000436	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
TPSea814_000437	ENOG41068FD	
TPSea814_000438	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TPSea814_000439	ENOG4105YFD	chemotaxis, protein
TPSea814_000441	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TPSea814_000442	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TPSea814_000446	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TPSea814_000446a	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TPSea814_000447	ENOG4106B9X	
TPSea814_000448	ENOG4107V28	uracil phosphoribosyltransferase
TPSea814_000449	ENOG4106VIZ	
TPSea814_000450	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TPSea814_000452	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TPSea814_000453	ENOG41071ED	
TPSea814_000454	ENOG4106UUF	
TPSea814_000456	ENOG4106U6F	
TPSea814_000458	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TPSea814_000459	ENOG4105FE9	pseudouridine synthase
TPSea814_000462	ENOG4106VGM	(LipO)protein
TPSea814_000464	ENOG4107W7Y	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TPSea814_000466	ENOG41090Q2	
TPSea814_000472	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TPSea814_000474	ENOG4105CDY	transcriptional regulatory protein
TPSea814_000475	ENOG4107QP8	phosphohexose isomerase
TPSea814_000476	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
TPSea814_000477	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
TPSea814_000478	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TPSea814_000480	ENOG4105RJI	
TPSea814_000481	ENOG410877G	
TPSea814_000484	ENOG4105J3I	
TPSea814_000485	ENOG4105F8J	Adenylate Guanylate cyclase
TPSea814_000488	ENOG4105C8Q	Methyl-accepting chemotaxis
TPSea814_000492	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TPSea814_000493	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPSea814_000497	ENOG4105DFF	Rod shape-determining protein mreb
TPSea814_000501	ENOG4105CNI	cell division protein FtsW
TPSea814_000502	ENOG41082BE	ankyrin repeat-containing protein
TPSea814_000503	ENOG4105ZF0	Lipoprotein
TPSea814_000506	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TPSea814_000507	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TPSea814_000508	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TPSea814_000509	ENOG4105D3R	alkyl hydroperoxide reductase
TPSea814_000510	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TPSea814_000511	ENOG4108VJ1	Transcriptional regulator (CarD family
TPSea814_000512	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TPSea814_000516	ENOG4105CJR	Integral membrane protein (MviN
TPSea814_000517	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TPSea814_000519	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TPSea814_000521	ENOG4107QRG	dna polymerase iii
TPSea814_000522	ENOG4107JR8	Colicin v production protein
TPSea814_000523	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TPSea814_000524	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TPSea814_000525	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TPSea814_000526	ENOG4105CQ7	ATP-dependent helicase
TPSea814_000527	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TPSea814_000528	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TPSea814_000529	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TPSea814_000533	ENOG4107WUB	V-type ATPase 116 kDa subunit
TPSea814_000536	ENOG4106447	Preprotein translocase subunit SecG
TPSea814_000537	ENOG4105CP7	Triose-phosphate isomerase
TPSea814_000538	ENOG4105BZA	Phosphoglycerate kinase
TPSea814_000540	ENOG4105WN5	stage II sporulation protein
TPSea814_000541	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TPSea814_000542	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
TPSea814_000543	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TPSea814_000546	ENOG4105C0H	protease
TPSea814_000547	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TPSea814_000548	ENOG4106J2Q	Uncharacterised protein family (UPF0164)
TPSea814_000549	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPSea814_000550	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TPSea814_000552	ENOG41062VP	
TPSea814_000553	ENOG4105F4G	Membrane
TPSea814_000554	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TPSea814_000556	ENOG4105CU9	asparagine synthetase A
TPSea814_000559	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TPSea814_000560	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TPSea814_000561	ENOG4105HA9	of methanol dehydrogenase type
TPSea814_000564	ENOG4106JH4	
TPSea814_000568	ENOG4108UHU	Aldolase
TPSea814_000569	ENOG4105DC7	peptidase M24
TPSea814_000572	ENOG4105I7V	membrAne
TPSea814_000574	ENOG4107TXU	
TPSea814_000574b	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TPSea814_000576	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TPSea814_000577	ENOG4106MPK	
TPSea814_000578	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TPSea814_000579	ENOG410774Y	
TPSea814_000580	ENOG4105D60	lipoprotein releasing system transmembrane protein
TPSea814_000581	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TPSea814_000584	ENOG4105G9E	
TPSea814_000586	ENOG4105C8T	Leucyl-tRNA synthetase
TPSea814_000589	ENOG4105KZ7	phosphocarrier protein hpr
TPSea814_000591	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TPSea814_000593	ENOG4106TP1	
TPSea814_000595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TPSea814_000596	ENOG4105DJ0	Poly(A) Polymerase
TPSea814_000598	ENOG4105X1A	
TPSea814_000599	ENOG41062Z1	
TPSea814_000600	ENOG4105DZP	Membrane-associated zinc metalloprotease
TPSea814_000601	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TPSea814_000603	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TPSea814_000604	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TPSea814_000605	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TPSea814_000606	ENOG4105CE9	30S ribosomal protein S2
TPSea814_000608	ENOG4105SXG	
TPSea814_000609	ENOG4105C5S	asparaginyl-tRNA synthetase
TPSea814_000612	ENOG4105DIW	FeS assembly protein SUFB
TPSea814_000614	ENOG4105C9B	Cysteine desulfurase
TPSea814_000616	ENOG4105E66	phosphoriboisomerase A
TPSea814_000623	ENOG4105E9H	Lytic Murein transglycosylase
TPSea814_000625	ENOG4106XHX	
TPSea814_000628	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TPSea814_000629	ENOG4106URY	
TPSea814_000630	ENOG4105BZU	Histidine kinase
TPSea814_000631	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TPSea814_000632	ENOG4105C31	Tryptophanyl-tRNA synthetase
TPSea814_000633	ENOG4105E0X	reductase
TPSea814_000634	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TPSea814_000637	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TPSea814_000638	ENOG41071ZZ	
TPSea814_000639	ENOG4105C8Q	Methyl-accepting chemotaxis
TPSea814_000641	ENOG4105CUT	histidyl-tRNA synthetase
TPSea814_000643	ENOG4108JDX	DNA polymerase iii, epsilon subunit
TPSea814_000644	ENOG4105DK7	lysyl-tRNA synthetase
TPSea814_000645	ENOG4105D38	putrescine abc transporter
TPSea814_000647	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TPSea814_000649	ENOG4105C37	(CBS) domain
TPSea814_000650	ENOG41082QW	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TPSea814_000652	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TPSea814_000653	ENOG4105F38	ABC transporter, permease
TPSea814_000655	ENOG4108HM4	ABC transporter
TPSea814_000657	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TPSea814_000658	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
TPSea814_000661	ENOG41069DF	
TPSea814_000662	ENOG4105D2N	Aldolase
TPSea814_000666	ENOG4106FRC	
TPSea814_000667	ENOG4105DBI	uridine monophosphokinase
TPSea814_000669	ENOG4105C0B	DNA polymerase III (alpha subunit)
TPSea814_000670	ENOG4105CPF	Cell wall formation (By similarity)
TPSea814_000672	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TPSea814_000673	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TPSea814_000674	ENOG4105XAB	Smr domain protein
TPSea814_000675	ENOG4105MBR	gumn family
TPSea814_000677	ENOG4105Z8J	
TPSea814_000678	ENOG41089XN	
TPSea814_000680	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TPSea814_000681	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TPSea814_000682	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TPSea814_000683	ENOG4105EAH	synthase
TPSea814_000684	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
TPSea814_000685	ENOG4105C2J	ABC transporter
TPSea814_000686	ENOG4107R2W	ABC transporter, permease
TPSea814_000687	ENOG4105CB5	ATP-dependent DNA helicase recG
TPSea814_000688	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
TPSea814_000689	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TPSea814_000692	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TPSea814_000693	ENOG4106GZE	
TPSea814_000695	ENOG4105C12	Phosphoribosylglycinamide synthetase
TPSea814_000700	ENOG4106AG2	
TPSea814_000701	ENOG41068UM	RNA Polymerase
TPSea814_000704	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TPSea814_000705	ENOG4108JQC	penicillin-binding protein 1A
TPSea814_000706	ENOG4105E4C	Lytic transglycosylase catalytic
TPSea814_000709	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPSea814_000711	ENOG4106FP0	
TPSea814_000714	ENOG4105D7B	Flagellar biosynthesis protein flha
TPSea814_000715	ENOG4105D00	flagellar biosynthetic protein flhB
TPSea814_000717	ENOG4105VS8	Flagellar biosynthetic protein fliq
TPSea814_000718	ENOG4105CN7	Flagellar biosynthetic protein FliP
TPSea814_000720	ENOG4105DD5	Flagellar motor switch protein
TPSea814_000721	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPSea814_000722	ENOG41064SM	flagellar basal body-associated protein flil
TPSea814_000724	ENOG4107XSU	flagellar motor protein motb
TPSea814_000725	ENOG4107R0U	MotA TolQ exbB proton channel
TPSea814_000727	ENOG4105BZE	flagellar hook protein, FlgE
TPSea814_000728	ENOG410822I	Flagellar hook capping protein
TPSea814_000732	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TPSea814_000733	ENOG4105XBK	
TPSea814_000734	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TPSea814_000735	ENOG4105BZ8	glutamate synthase
TPSea814_000736	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TPSea814_000738	ENOG4107ZFZ	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TPSea814_000741	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TPSea814_000742	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TPSea814_000743	ENOG4105K46	50S ribosomal protein l27
TPSea814_000745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TPSea814_000746	ENOG4107QJD	pyruvate phosphate dikinase
TPSea814_000747	ENOG4108SXE	
TPSea814_000748	ENOG41073RW	Cytoplasmic filament protein A
TPSea814_000750	ENOG4105YQK	von Willebrand factor type A domain
TPSea814_000751	ENOG4106BN6	
TPSea814_000752	ENOG41073FS	
TPSea814_000754	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TPSea814_000755	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TPSea814_000756	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TPSea814_000757	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TPSea814_000758	ENOG41084YP	30S ribosomal protein S21
TPSea814_000760	ENOG4105CJN	penicillin-binding protein
TPSea814_000762	ENOG4107YZD	Protein of unknown function DUF115
TPSea814_000763	ENOG41063XV	
TPSea814_000765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TPSea814_000767	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TPSea814_000768	ENOG4106UV5	membrane protein A
TPSea814_000769	ENOG4108I7Y	domain protein
TPSea814_000770	ENOG4105C1J	atp-dependent rna helicase
TPSea814_000771	ENOG4105EAM	Na Pi-cotransporter
TPSea814_000772	ENOG4106S0F	
TPSea814_000773	ENOG4105C0H	protease
TPSea814_000774	ENOG4105KT7	mgtC SapB transporter
TPSea814_000775	ENOG4105CSM	endonuclease III
TPSea814_000777	ENOG4106XCQ	Inherit from COG: Pfam:DUF82
TPSea814_000778	ENOG4105DXN	mazG family
TPSea814_000779	ENOG41083CW	dedA protein
TPSea814_000780	ENOG4107QMG	Nad synthetase
TPSea814_000783	ENOG410684W	
TPSea814_000784	ENOG4106X59	Pfam:DUF1239
TPSea814_000786	ENOG4108IUZ	ABC transporter
TPSea814_000788	ENOG41061XC	
TPSea814_000789	ENOG4108M1M	outer membrane lipoprotein-sorting protein
TPSea814_000792	ENOG4105I03	Flagellin
TPSea814_000793	ENOG4106N2C	
TPSea814_000794	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TPSea814_000796	ENOG4105CJ2	(LipO)protein
TPSea814_000797	ENOG4105II7	pyrroline-5-carboxylate reductase
TPSea814_000800	ENOG4105DZ1	carboxypeptidase
TPSea814_000801	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPSea814_000807	ENOG41085D1	50S ribosomal protein L32
TPSea814_000808	ENOG41084E5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TPSea814_000809	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TPSea814_000810	ENOG4107R5S	dna adenine
TPSea814_000813	ENOG41090QR	
TPSea814_000814	ENOG4105C3M	thioredoxin reductase
TPSea814_000816	ENOG4106TEA	
TPSea814_000817	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TPSea814_000819	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TPSea814_000821	ENOG4105D01	(LipO)protein
TPSea814_000823	ENOG4105MAX	Superoxide reductase
TPSea814_000824	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TPSea814_000828	ENOG41083V3	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TPSea814_000829	ENOG4108CER	Uncharacterized protein conserved in bacteria (DUF2225)
TPSea814_000830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TPSea814_000831	ENOG4105C75	arginyL-tRNA synthetase
TPSea814_000834	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TPSea814_000836	ENOG4105VVB	
TPSea814_000837	ENOG4105C22	threonyL-tRNA synthetase
TPSea814_000838	ENOG4105C5H	ABC transporter
TPSea814_000841	ENOG4105C0H	protease
TPSea814_000842	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TPSea814_000843	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPSea814_000844	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TPSea814_000845	ENOG41082MQ	UPF0178 protein
TPSea814_000846	ENOG4106BMT	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TPSea814_000847	ENOG4106BH8	
TPSea814_000848	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TPSea814_000849	ENOG41084MZ	50S ribosomal protein L35
TPSea814_000850	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TPSea814_000851	ENOG4105HCZ	
TPSea814_000852	ENOG4107WGG	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TPSea814_000853	ENOG4107R21	site-determining protein
TPSea814_000861	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TPSea814_000862	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TPSea814_000863	ENOG4107QI6	Cysteine desulfurase
TPSea814_000864	ENOG41068JE	domain protein
TPSea814_000865a	ENOG4105C0P	Mg chelatase subunit ChlI
TPSea814_000868	ENOG4105I03	Flagellin
TPSea814_000870	ENOG4105I03	Flagellin
TPSea814_000873	ENOG4106SAP	
TPSea814_000875	ENOG4105K8N	protein family UPF0079, ATPase
TPSea814_000876	ENOG41072GX	Peptidase M22 Glycoprotease
TPSea814_000877	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TPSea814_000878	ENOG4106QPK	
TPSea814_000881	ENOG4108IUW	ABC transporter
TPSea814_000885	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TPSea814_000886	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TPSea814_000887	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TPSea814_000889	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TPSea814_000890	ENOG41080JB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TPSea814_000891	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TPSea814_000892	ENOG4105CHV	Transcription elongation factor NusA
TPSea814_000893	ENOG410854D	Required for maturation of 30S ribosomal subunits (By similarity)
TPSea814_000901	ENOG4107QMU	Mate efflux family protein
TPSea814_000903	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TPSea814_000905	ENOG4105K5M	30s ribosomal protein S16
TPSea814_000906	ENOG4105VB6	UPF0109 protein
TPSea814_000907	ENOG4107GQ3	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TPSea814_000908	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TPSea814_000909	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TPSea814_000911	ENOG4105VM1	flagellar
TPSea814_000912	ENOG4105CPI	Metal Dependent Phosphohydrolase
TPSea814_000913	ENOG41082I4	UPF0102 protein
TPSea814_000917	ENOG4105CJW	magnesium transporter
TPSea814_000919	ENOG4105K63	Thioredoxin
TPSea814_000920	ENOG4108QUE	repeat-containing protein
TPSea814_000925	ENOG4108Z29	Flavodoxin
TPSea814_000926	ENOG4105C3F	Signal peptidase i
TPSea814_000930	ENOG4106SUR	Protein of unknown function DUF115
TPSea814_000931	ENOG4107MD5	glycoside hydrolase, family
TPSea814_000933	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TPSea814_000938	ENOG4106W1H	
TPSea814_000939	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TPSea814_000941	ENOG4106RHC	
TPSea814_000942	ENOG4106VWR	
TPSea814_000945	ENOG4105DJV	ribulose-phosphate 3-epimerase
TPSea814_000946	ENOG41083HS	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TPSea814_000947	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TPSea814_000949	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TPSea814_000949a	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TPSea814_000949b	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TPSea814_000951	ENOG4105VG0	50S ribosomal protein l34
TPSea814_000956	ENOG41081IW	Inherit from COG: Membrane
TPSea814_000958	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TPSea814_000959	ENOG410680E	Flagellar protein
TPSea814_000960	ENOG4105CGA	flagellar basal-body rod protein FlgG
TPSea814_000963	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TPSea814_000964	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TPSea814_000965	ENOG410624X	efflux transporter, rnd family, mfp subunit
TPSea814_000966	ENOG4106KIQ	
TPSea814_000967	ENOG4106KIQ	
TPSea814_000971	ENOG4108SDV	Periplasmic Protein
TPSea814_000972	ENOG4107SJW	iron permease, FTR1
TPSea814_000973	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TPSea814_000974	ENOG4105ZAM	anti-sigma-28 factor flgm family protein
TPSea814_000975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TPSea814_000976	ENOG4106WPJ	
TPSea814_000977	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TPSea814_000978	ENOG410835P	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TPSea814_000979	ENOG4105F8V	Hydrolase, tatD family
TPSea814_000980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TPSea814_000981	ENOG4105BZU	Histidine kinase
TPSea814_000983	ENOG4105Y6R	
TPSea814_000984	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TPSea814_000985	ENOG4105C9M	aspartyl-trna synthetase
TPSea814_000988	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
TPSea814_000991	ENOG4105VCQ	rubredoxin
TPSea814_000993	ENOG4105K6T	rare lipoprotein A
TPSea814_000994	ENOG4105F8V	Hydrolase, tatD family
TPSea814_000997	ENOG4105D07	Signal peptide peptidase, SppA
TPSea814_000998	ENOG4105BZG	amino acid carrier protein
TPSea814_000999	ENOG4105CNU	cell division protein FtsK
TPSea814_001001	ENOG4105TQV	
TPSea814_001003	ENOG4106SWD	
TPSea814_001004	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TPSea814_001005	ENOG4105C6E	dna polymerase iii
TPSea814_001006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TPSea814_001007	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TPSea814_001008	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TPSea814_001009	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TPSea814_001010	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TPSea814_001011	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TPSea814_001012	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPSea814_001013	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TPSea814_001014	ENOG4106JWJ	
TPSea814_001015	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TPSea814_001016	ENOG4107Z25	Basic membrane protein
TPSea814_001017	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TPSea814_001018	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TPSea814_001019	ENOG4107I15	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TPSea814_001020	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TPSea814_001021	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TPSea814_001022	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TPSea814_001023	ENOG410691R	Modulates RecA activity (By similarity)
TPSea814_001024	ENOG4108UJD	30S ribosomal protein S9
TPSea814_001025	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TPSea814_001027	ENOG4108I5U	Uridine phosphorylase
TPSea814_001029	ENOG41062BZ	domain protein
TPSea814_001032	ENOG41085BT	Protein of unknown function (DUF1312)
TPSea814_001033	ENOG4105D78	K07001 NTE family protein
TPSea814_001034	ENOG4105FEU	K -dependent Na -Ca exchanger
TPSea814_001035	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TPSea814_001037	ENOG4108UT2	hemolysin iii
TPSea814_001038	ENOG4108RMU	ferritin dps family protein
TPSea814_001039	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TPSea814_001040	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TPSea814_001041	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)