locus-tag	class	description
TPCCA_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TPCCA_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TPCCA_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TPCCA_0004	ENOG4106C4Y	Protein of unknown function (DUF721)
TPCCA_0005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TPCCA_0006	ENOG4105K95	(LipO)protein
TPCCA_0013	ENOG4105K95	(LipO)protein
TPCCA_0015	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
TPCCA_0016	ENOG4105DAN	ATP-dependent protease
TPCCA_0021	ENOG4105T73	
TPCCA_0023	ENOG4105C8J	)-transporter
TPCCA_0025	ENOG4107QYI	peptidase
TPCCA_0026	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPCCA_0029	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TPCCA_0030	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TPCCA_0032	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TPCCA_0034	ENOG4105DSE	periplasmic solute binding protein
TPCCA_0035	ENOG4105FDK	ABC transporter
TPCCA_0036	ENOG4105FAV	ABC, transporter
TPCCA_0037	ENOG4105C5I	Dehydrogenase
TPCCA_0040	ENOG4108NVR	Methyl-accepting chemotaxis
TPCCA_0042	ENOG4108WZM	domain protein
TPCCA_0044	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TPCCA_0045	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
TPCCA_0046	ENOG4105MA4	psp1 domain protein
TPCCA_0049	ENOG4105DR5	peptidase
TPCCA_0052	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TPCCA_0053	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TPCCA_0056	ENOG4107QSA	Oxaloacetate decarboxylase
TPCCA_0057	ENOG4105D9Q	decarboxylase (Beta subunit)
TPCCA_0058	ENOG4105CDU	Replicative dna helicase
TPCCA_0060	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TPCCA_0061	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TPCCA_0062	ENOG4105Z8H	single-stranded DNA-binding protein
TPCCA_0063	ENOG41084AY	Binds together with S18 to 16S ribosomal RNA (By similarity)
TPCCA_0064	ENOG4106YRG	
TPCCA_0066	ENOG4105ZFX	
TPCCA_0068	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TPCCA_0069	ENOG4106XJW	
TPCCA_0070	ENOG4106D63	
TPCCA_0071	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPCCA_0073	ENOG4108HU6	Metal dependent phosphohydrolase
TPCCA_0075	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
TPCCA_0076	ENOG4105DRS	transport system, permease
TPCCA_0078	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TPCCA_0082	ENOG4108JUA	Transcriptional regulator
TPCCA_0084	ENOG41077G2	
TPCCA_0085	ENOG4105DM4	PTS System
TPCCA_0086	ENOG4105G3C	Type iv pilus assembly
TPCCA_0089	ENOG4105IJJ	transcriptional regulator, crp fnr family
TPCCA_0090	ENOG4107QWW	Cell wall formation (By similarity)
TPCCA_0091	ENOG4105C8N	cysteinyl-tRNA synthetase
TPCCA_0092	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPCCA_0094	ENOG4108IJ2	phosphate acetyltransferase
TPCCA_0095	ENOG4107GWN	repeat protein
TPCCA_0097	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TPCCA_0098	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPCCA_0100	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TPCCA_0101	ENOG4107QIV	Cytochrome c biogenesis protein
TPCCA_0104	ENOG4105CGH	5'-nucleotidase
TPCCA_0105	ENOG4105C2M	dna polymerase I
TPCCA_0108	ENOG4105CTQ	phosphohexokinase
TPCCA_0110	ENOG41090KZ	
TPCCA_0111	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPCCA_0112	ENOG4105CTZ	aminopeptidase c
TPCCA_0113	ENOG4107RIZ	hflk protein
TPCCA_0114	ENOG4105EPW	hflc protein
TPCCA_0115	ENOG4105DWF	phosphomethylpyrimidine kinase
TPCCA_0116	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TPCCA_0118	ENOG4106V14	
TPCCA_0119	ENOG4108UMI	ABC transporter, permease
TPCCA_0120	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TPCCA_0121	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TPCCA_0122	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TPCCA_0123	ENOG4106AHS	
TPCCA_0124	ENOG4105C3G	gtp-binding protein
TPCCA_0125	ENOG4105CGK	Exodeoxyribonuclease III
TPCCA_0133	ENOG4106VGM	(LipO)protein
TPCCA_0136	ENOG4106VGM	(LipO)protein
TPCCA_0138	ENOG4106S4G	
TPCCA_0139	ENOG4107ZYR	domain protein
TPCCA_0140	ENOG4105CZN	Potassium uptake protein
TPCCA_0141	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TPCCA_0142	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TPCCA_0145	ENOG4108IQE	Amp-dependent synthetase and ligase
TPCCA_0147	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TPCCA_0148	ENOG4106Y0N	
TPCCA_0149	ENOG4106VF0	
TPCCA_0150	ENOG4107AGI	
TPCCA_0159	ENOG4106KG8	
TPCCA_0160	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TPCCA_0162	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TPCCA_0163	ENOG4107SIG	periplasmic solute binding protein
TPCCA_0164	ENOG4105DIK	(ABC) transporter
TPCCA_0165	ENOG4107RPQ	ABC transporter
TPCCA_0166	ENOG4107RBD	ABC, transporter
TPCCA_0168	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TPCCA_0170	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TPCCA_0171	ENOG41088B0	Major membrane immunogen
TPCCA_0174	ENOG41090QV	Protein of unknown function DUF115
TPCCA_0177	ENOG4105X4X	Protein of unknown function DUF115
TPCCA_0179	ENOG410698I	
TPCCA_0181	ENOG4106U5D	Septum formation initiator
TPCCA_0183	ENOG4106QD2	
TPCCA_0184	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TPCCA_0185	ENOG4105C3F	Signal peptidase i
TPCCA_0186	ENOG4105CSA	Coproporphyrinogen iii oxidase
TPCCA_0187	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TPCCA_0188	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TPCCA_0189	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TPCCA_0190	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TPCCA_0191	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TPCCA_0192	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TPCCA_0193	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TPCCA_0194	ENOG41082G4	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TPCCA_0195	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TPCCA_0196	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TPCCA_0198	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TPCCA_0199	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TPCCA_0200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TPCCA_0201	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TPCCA_0203	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TPCCA_0204	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TPCCA_0205	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TPCCA_0206	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TPCCA_0207	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TPCCA_0208	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TPCCA_0209	ENOG41067V7	50S ribosomal protein L36
TPCCA_0210	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TPCCA_0211	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TPCCA_0212	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPCCA_0213	ENOG4108ZT0	50S ribosomal protein l17
TPCCA_0214	ENOG4106DC9	
TPCCA_0215	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TPCCA_0216	ENOG4105CFG	Acts as a chaperone (By similarity)
TPCCA_0217	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPCCA_0220	ENOG4105WN5	stage II sporulation protein
TPCCA_0227	ENOG4108JJB	ABC transporter
TPCCA_0228	ENOG4105VKD	bioY protein
TPCCA_0229	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TPCCA_0230	ENOG4105C25	Primosomal protein n'
TPCCA_0231	ENOG4105EI2	Pseudouridine synthase
TPCCA_0234	ENOG41084ED	50S ribosomal protein L33
TPCCA_0236	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TPCCA_0237	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TPCCA_0238	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TPCCA_0239	ENOG4108VZM	50s ribosomal protein L10
TPCCA_0240	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TPCCA_0241	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPCCA_0242	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TPCCA_0243	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TPCCA_0244	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TPCCA_0247	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TPCCA_0248	ENOG4106UC9	
TPCCA_0249	ENOG4107NGC	Flagellar filament outer layer protein
TPCCA_0252	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TPCCA_0254	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TPCCA_0255	ENOG41082DI	50s ribosomal protein l31
TPCCA_0256	ENOG41081GK	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase
TPCCA_0257	ENOG4107YU0	Glycerophosphoryl diester phosphodiesterase family
TPCCA_0260	ENOG4105I76	(LipO)protein
TPCCA_0262	ENOG4105IJJ	transcriptional regulator, crp fnr family
TPCCA_0264	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TPCCA_0269	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TPCCA_0270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TPCCA_0271	ENOG4105FA0	parb-like partition protein
TPCCA_0272	ENOG4107QJE	Chromosome Partitioning Protein
TPCCA_0277	ENOG4105CN1	protease
TPCCA_0279	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TPCCA_0282	ENOG4105W0I	repeat-containing protein
TPCCA_0283	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TPCCA_0284	ENOG4108ZVA	radical SAM domain protein
TPCCA_0288	ENOG4107TY6	Acylneuraminate cytidylyltransferase
TPCCA_0290	ENOG4108HCJ	Hydrolase
TPCCA_0292	ENOG4107QKZ	Ompa motb domain protein
TPCCA_0294	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TPCCA_0296	ENOG41083NY	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TPCCA_0298	ENOG4108SSC	basic membrane
TPCCA_0301	ENOG4108TWB	ABC transporter (Permease
TPCCA_0302	ENOG4108ZV0	ABC transporter, permease
TPCCA_0303	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TPCCA_0304	ENOG4105MB2	
TPCCA_0305	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TPCCA_0306	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TPCCA_0308	ENOG4105E89	ABC transporter
TPCCA_0319	ENOG4107TFB	basic membrane
TPCCA_0321	ENOG4108JQ9	ABC transporter
TPCCA_0322	ENOG4105UIB	(ABC) transporter
TPCCA_0326	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TPCCA_0328	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TPCCA_0329	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TPCCA_0331	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TPCCA_0337	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TPCCA_0340	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TPCCA_0341	ENOG4105DFU	Cell wall formation (By similarity)
TPCCA_0342	ENOG4108Z4J	Cytidine monophosphate kinase
TPCCA_0344	ENOG4108JA2	transcriptioN-repair coupling factor
TPCCA_0345	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TPCCA_0349	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TPCCA_0350	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TPCCA_0351	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TPCCA_0352	ENOG4105VEM	Conserved domain protein
TPCCA_0353	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TPCCA_0354	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TPCCA_0357	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TPCCA_0358	ENOG4107RFW	hydrolase family 57
TPCCA_0359	ENOG4106ARS	
TPCCA_0362	ENOG41084P6	50S ribosomal protein l28
TPCCA_0363	ENOG4105CBS	Chea signal transduction histidine kinase
TPCCA_0364	ENOG4105YFD	chemotaxis, protein
TPCCA_0366	ENOG4107Z9R	response regulator
TPCCA_0367	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TPCCA_0369	ENOG4106GEY	
TPCCA_0371	ENOG4107SJN	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TPCCA_0372	ENOG4107TVT	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TPCCA_0373	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TPCCA_0374	ENOG41069X2	
TPCCA_0376	ENOG4107I03	
TPCCA_0379	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TPCCA_0381	ENOG410615F	Integral membrane protein (intg_mem_TP0381)
TPCCA_0383	ENOG4107YM1	mraZ protein
TPCCA_0384	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TPCCA_0386	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TPCCA_0387	ENOG4105CNI	cell division protein FtsW
TPCCA_0388	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
TPCCA_0389	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TPCCA_0390	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TPCCA_0391	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TPCCA_0393	ENOG4105C79	DNA protecting protein DprA
TPCCA_0394	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TPCCA_0395	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TPCCA_0396	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
TPCCA_0397	ENOG4108ZC9	flagellar basal-body rod protein flgc
TPCCA_0398	ENOG41069WH	flagellar hook-basal body complex
TPCCA_0399	ENOG4107U2N	Flagellar M-ring protein
TPCCA_0400	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPCCA_0401	ENOG4105W2B	Flagellar assembly protein
TPCCA_0402	ENOG4108JIR	Flagellum-specific ATP synthase
TPCCA_0404	ENOG4108346	Beta-lactamase domain protein
TPCCA_0406	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TPCCA_0410	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TPCCA_0411	ENOG4107XHD	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TPCCA_0414	ENOG4105BZG	amino acid carrier protein
TPCCA_0417	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TPCCA_0418	ENOG41080VC	Galactokinase (EC 2.7.1.6)
TPCCA_0419	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TPCCA_0422	ENOG4106R77	
TPCCA_0424	ENOG4108RY1	ATP synthase, subunit E
TPCCA_0426	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TPCCA_0427	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TPCCA_0428	ENOG4108WBK	V-type ATP synthase subunit D
TPCCA_0429	ENOG4107U1W	v-type ATP synthase subunit I
TPCCA_0431	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TPCCA_0436	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
TPCCA_0437	ENOG41068FD	
TPCCA_0438	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TPCCA_0439	ENOG4105YFD	chemotaxis, protein
TPCCA_0441	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TPCCA_0442	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TPCCA_0446	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TPCCA_0447	ENOG4106B9X	
TPCCA_0448	ENOG4107V28	uracil phosphoribosyltransferase
TPCCA_0449	ENOG4106VIZ	
TPCCA_0450	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TPCCA_0452	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TPCCA_0453	ENOG41071ED	
TPCCA_0454	ENOG4106UUF	
TPCCA_0456	ENOG4106U6F	
TPCCA_0458	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TPCCA_0459	ENOG4105FE9	pseudouridine synthase
TPCCA_0462	ENOG4106VGM	(LipO)protein
TPCCA_0464	ENOG4107W7Y	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TPCCA_0466	ENOG41090Q2	
TPCCA_0472	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TPCCA_0474	ENOG4105CDY	transcriptional regulatory protein
TPCCA_0475	ENOG4107QP8	phosphohexose isomerase
TPCCA_0476	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
TPCCA_0477	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
TPCCA_0478	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
TPCCA_0480	ENOG4105RJI	
TPCCA_0481	ENOG410877G	
TPCCA_0484	ENOG4105J3I	
TPCCA_0485	ENOG4105F8J	Adenylate Guanylate cyclase
TPCCA_0487	ENOG4107GGS	
TPCCA_0491	ENOG4105HHA	aminodeoxychorismate lyase
TPCCA_0492	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TPCCA_0493	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPCCA_0497	ENOG4105DFF	Rod shape-determining protein mreb
TPCCA_0500	ENOG4105CJN	penicillin-binding protein
TPCCA_0501	ENOG4105CNI	cell division protein FtsW
TPCCA_0502	ENOG41082BE	ankyrin repeat-containing protein
TPCCA_0503	ENOG4105ZF0	Lipoprotein
TPCCA_0506	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TPCCA_0507	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TPCCA_0508	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TPCCA_0509	ENOG4105D3R	alkyl hydroperoxide reductase
TPCCA_0510	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TPCCA_0511	ENOG4108VJ1	Transcriptional regulator (CarD family
TPCCA_0512	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TPCCA_0514	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TPCCA_0516	ENOG4105CJR	Integral membrane protein (MviN
TPCCA_0517	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TPCCA_0519	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TPCCA_0520	ENOG4105BZU	Histidine kinase
TPCCA_0521	ENOG4105FA2	dna polymerase iii
TPCCA_0522	ENOG4107JR8	Colicin v production protein
TPCCA_0523	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TPCCA_0524	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TPCCA_0525	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TPCCA_0526	ENOG4105CQ7	ATP-dependent helicase
TPCCA_0527	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TPCCA_0528	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TPCCA_0529	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TPCCA_0533	ENOG4107WUB	V-type ATPase 116 kDa subunit
TPCCA_0536	ENOG4106447	Preprotein translocase subunit SecG
TPCCA_0537	ENOG4105CP7	Triose-phosphate isomerase
TPCCA_0538	ENOG4105BZA	Phosphoglycerate kinase
TPCCA_0540	ENOG4105WN5	stage II sporulation protein
TPCCA_0541	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TPCCA_0542	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
TPCCA_0543	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TPCCA_0546	ENOG4105C0H	protease
TPCCA_0547	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TPCCA_0548	ENOG4106J2Q	Uncharacterised protein family (UPF0164)
TPCCA_0549	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPCCA_0550	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TPCCA_0552	ENOG41062VP	
TPCCA_0553	ENOG4105F4G	Membrane
TPCCA_0554	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TPCCA_0556	ENOG4105CU9	asparagine synthetase A
TPCCA_0560	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TPCCA_0561	ENOG4105HA9	of methanol dehydrogenase type
TPCCA_0564	ENOG4106JH4	
TPCCA_0566	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
TPCCA_0568	ENOG4108UHU	Aldolase
TPCCA_0569	ENOG4105DC7	peptidase M24
TPCCA_0572	ENOG4105I7V	membrAne
TPCCA_0574	ENOG4107TXU	
TPCCA_0575	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TPCCA_0576	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TPCCA_0577	ENOG4106MPK	
TPCCA_0578	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TPCCA_0579	ENOG410774Y	
TPCCA_0580	ENOG4105D60	lipoprotein releasing system transmembrane protein
TPCCA_0581	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TPCCA_0584	ENOG4105G9E	
TPCCA_0586	ENOG4105C8T	Leucyl-tRNA synthetase
TPCCA_0589	ENOG4105KZ7	phosphocarrier protein hpr
TPCCA_0591	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TPCCA_0593	ENOG4106TP1	
TPCCA_0595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TPCCA_0596	ENOG4105DJ0	Poly(A) Polymerase
TPCCA_0597	ENOG4105X1A	
TPCCA_0599	ENOG41062Z1	
TPCCA_0600	ENOG4105DZP	Membrane-associated zinc metalloprotease
TPCCA_0601	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TPCCA_0603	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TPCCA_0604	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TPCCA_0605	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TPCCA_0606	ENOG4105CE9	30S ribosomal protein S2
TPCCA_0608	ENOG4105SXG	
TPCCA_0609	ENOG4105C5S	asparaginyl-tRNA synthetase
TPCCA_0612	ENOG4105DIW	FeS assembly protein SUFB
TPCCA_0614	ENOG4105C9B	Cysteine desulfurase
TPCCA_0616	ENOG4105E66	phosphoriboisomerase A
TPCCA_0623	ENOG4105E9H	Lytic Murein transglycosylase
TPCCA_0625	ENOG4106XHX	
TPCCA_0626	ENOG4107RFY	SbcCD D subunit
TPCCA_0627	ENOG4105EYH	Exonuclease
TPCCA_0628	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TPCCA_0629	ENOG4106URY	
TPCCA_0630	ENOG4105BZU	Histidine kinase
TPCCA_0631	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TPCCA_0632	ENOG4105C31	Tryptophanyl-tRNA synthetase
TPCCA_0633	ENOG4105E0X	reductase
TPCCA_0634	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TPCCA_0637	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TPCCA_0638	ENOG41071ZZ	
TPCCA_0639	ENOG4105C8Q	Methyl-accepting chemotaxis
TPCCA_0640	ENOG4105EC8	Methyl-accepting chemotaxis
TPCCA_0641	ENOG4105CUT	histidyl-tRNA synthetase
TPCCA_0643	ENOG4108JDX	DNA polymerase iii, epsilon subunit
TPCCA_0644	ENOG4105DK7	lysyl-tRNA synthetase
TPCCA_0647	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TPCCA_0649	ENOG4105C37	(CBS) domain
TPCCA_0650	ENOG41082QW	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TPCCA_0651	ENOG4105CTJ	Metal Dependent Phosphohydrolase
TPCCA_0652	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TPCCA_0653	ENOG4105F38	ABC transporter, permease
TPCCA_0654	ENOG4105D38	putrescine abc transporter
TPCCA_0655	ENOG4108HM4	ABC transporter
TPCCA_0657	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TPCCA_0658	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
TPCCA_0661	ENOG41069DF	
TPCCA_0662	ENOG4105D2N	Aldolase
TPCCA_0665	ENOG4105JTB	
TPCCA_0666	ENOG4106FRC	
TPCCA_0667	ENOG4105DBI	uridine monophosphokinase
TPCCA_0669	ENOG4105C0B	DNA polymerase III (alpha subunit)
TPCCA_0670	ENOG4105CPF	Cell wall formation (By similarity)
TPCCA_0672	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TPCCA_0673	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TPCCA_0674	ENOG4105XAB	Smr domain protein
TPCCA_0675	ENOG4105MBR	gumn family
TPCCA_0677	ENOG4105Z8J	
TPCCA_0678	ENOG41089XN	
TPCCA_0680	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TPCCA_0681	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TPCCA_0682	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TPCCA_0683	ENOG4105EAH	synthase
TPCCA_0684	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
TPCCA_0685	ENOG4105C2J	ABC transporter
TPCCA_0686	ENOG4107R2W	ABC transporter, permease
TPCCA_0687	ENOG4105CB5	ATP-dependent DNA helicase recG
TPCCA_0688	ENOG4105EU2	peptidase U61 LD-carboxypeptidase A
TPCCA_0689	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TPCCA_0690	ENOG410750H	
TPCCA_0692	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TPCCA_0693	ENOG4106GZE	
TPCCA_0695	ENOG4105C12	Phosphoribosylglycinamide synthetase
TPCCA_0700	ENOG4106AG2	
TPCCA_0701	ENOG41068UM	RNA Polymerase
TPCCA_0704	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TPCCA_0705	ENOG4108JQC	penicillin-binding protein 1A
TPCCA_0706	ENOG4105E4C	Lytic transglycosylase catalytic
TPCCA_0709	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPCCA_0711	ENOG4106FP0	
TPCCA_0713	ENOG4105FZW	flagellar biosynthesis regulator FlhF
TPCCA_0714	ENOG4105D7B	Flagellar biosynthesis protein flha
TPCCA_0715	ENOG4105D00	flagellar biosynthetic protein flhB
TPCCA_0716	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
TPCCA_0717	ENOG4105VS8	Flagellar biosynthetic protein fliq
TPCCA_0718	ENOG4105CN7	Flagellar biosynthetic protein FliP
TPCCA_0720	ENOG4105DD5	Flagellar motor switch protein
TPCCA_0721	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
TPCCA_0722	ENOG41064SM	flagellar basal body-associated protein flil
TPCCA_0724	ENOG4107XSU	flagellar motor protein motb
TPCCA_0725	ENOG4107R0U	MotA TolQ exbB proton channel
TPCCA_0727	ENOG4105BZE	flagellar hook protein, FlgE
TPCCA_0728	ENOG410822I	Flagellar hook capping protein
TPCCA_0732	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TPCCA_0733	ENOG4105XBK	
TPCCA_0734	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TPCCA_0735	ENOG4105BZ8	glutamate synthase
TPCCA_0736	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TPCCA_0738	ENOG4107ZFZ	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
TPCCA_0741	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TPCCA_0742	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TPCCA_0743	ENOG4105K46	50S ribosomal protein l27
TPCCA_0745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TPCCA_0746	ENOG4107QJD	pyruvate phosphate dikinase
TPCCA_0747	ENOG4108SXE	
TPCCA_0748	ENOG41073RW	Cytoplasmic filament protein A
TPCCA_0750	ENOG4105YQK	von Willebrand factor type A domain
TPCCA_0751	ENOG4106BN6	
TPCCA_0752	ENOG41073FS	
TPCCA_0754	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TPCCA_0755	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TPCCA_0756	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TPCCA_0757	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TPCCA_0758	ENOG41084YP	30S ribosomal protein S21
TPCCA_0760	ENOG4105CJN	penicillin-binding protein
TPCCA_0762	ENOG4107YZD	Protein of unknown function DUF115
TPCCA_0763	ENOG41063XV	
TPCCA_0765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TPCCA_0767	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TPCCA_0768	ENOG4106UV5	membrane protein A
TPCCA_0769	ENOG4108I7Y	domain protein
TPCCA_0770	ENOG4105C1J	atp-dependent rna helicase
TPCCA_0771	ENOG4105EAM	Na Pi-cotransporter
TPCCA_0772	ENOG4106S0F	
TPCCA_0773	ENOG4105C0H	protease
TPCCA_0774	ENOG4105KT7	mgtC SapB transporter
TPCCA_0775	ENOG4105CSM	endonuclease III
TPCCA_0777	ENOG4106XCQ	Inherit from COG: Pfam:DUF82
TPCCA_0778	ENOG4105DXN	mazG family
TPCCA_0779	ENOG41083CW	dedA protein
TPCCA_0780	ENOG4107QMG	Nad synthetase
TPCCA_0783	ENOG410684W	
TPCCA_0784	ENOG4106X59	Pfam:DUF1239
TPCCA_0786	ENOG4108IUZ	ABC transporter
TPCCA_0788	ENOG41061XC	
TPCCA_0789	ENOG4108M1M	outer membrane lipoprotein-sorting protein
TPCCA_0792	ENOG4105I03	Flagellin
TPCCA_0793	ENOG4106N2C	
TPCCA_0794	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TPCCA_0796	ENOG4105CJ2	(LipO)protein
TPCCA_0797	ENOG4105II7	pyrroline-5-carboxylate reductase
TPCCA_0798	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TPCCA_0800	ENOG4105DZ1	carboxypeptidase
TPCCA_0801	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TPCCA_0807	ENOG41085D1	50S ribosomal protein L32
TPCCA_0808	ENOG41084E5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TPCCA_0809	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
TPCCA_0810	ENOG4107R5S	dna adenine
TPCCA_0813	ENOG41090QR	
TPCCA_0814	ENOG4105C3M	thioredoxin reductase
TPCCA_0816	ENOG4106TEA	
TPCCA_0817	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TPCCA_0819	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TPCCA_0821	ENOG4105D01	(LipO)protein
TPCCA_0823	ENOG4105MAX	Superoxide reductase
TPCCA_0824	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TPCCA_0828	ENOG41083V3	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TPCCA_0829	ENOG4108CER	Uncharacterized protein conserved in bacteria (DUF2225)
TPCCA_0830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TPCCA_0831	ENOG4105C75	arginyL-tRNA synthetase
TPCCA_0834	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TPCCA_0836	ENOG4105VVB	
TPCCA_0837	ENOG4105C22	threonyL-tRNA synthetase
TPCCA_0838	ENOG4105C5H	ABC transporter
TPCCA_0841	ENOG4105C0H	protease
TPCCA_0842	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TPCCA_0843	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TPCCA_0844	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TPCCA_0845	ENOG41082MQ	UPF0178 protein
TPCCA_0846	ENOG4106BMT	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TPCCA_0847	ENOG4106BH8	
TPCCA_0848	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TPCCA_0849	ENOG41084MZ	50S ribosomal protein L35
TPCCA_0850	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TPCCA_0851	ENOG4105HCZ	
TPCCA_0852	ENOG4107WGG	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TPCCA_0853	ENOG4107R21	site-determining protein
TPCCA_0855	ENOG4106NKH	
TPCCA_0861	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TPCCA_0862	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TPCCA_0863	ENOG4107QI6	Cysteine desulfurase
TPCCA_0864	ENOG41068JE	domain protein
TPCCA_0866	ENOG4105C0P	Mg chelatase subunit ChlI
TPCCA_0868	ENOG4105I03	Flagellin
TPCCA_0870	ENOG4105I03	Flagellin
TPCCA_0872	ENOG4107VE5	flagellar hook-associated protein
TPCCA_0873	ENOG4106SAP	
TPCCA_0875	ENOG4105K8N	protein family UPF0079, ATPase
TPCCA_0876	ENOG41072GX	Peptidase M22 Glycoprotease
TPCCA_0877	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TPCCA_0878	ENOG4106QPK	
TPCCA_0881	ENOG4108IUW	ABC transporter
TPCCA_0885	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
TPCCA_0886	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TPCCA_0887	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TPCCA_0889	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TPCCA_0890	ENOG41080JB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TPCCA_0891	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TPCCA_0892	ENOG4105CHV	Transcription elongation factor NusA
TPCCA_0893	ENOG410854D	Required for maturation of 30S ribosomal subunits (By similarity)
TPCCA_0899	ENOG4109031	
TPCCA_0901	ENOG4107QMU	Mate efflux family protein
TPCCA_0903	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TPCCA_0905	ENOG4105K5M	30s ribosomal protein S16
TPCCA_0906	ENOG4105VB6	UPF0109 protein
TPCCA_0907	ENOG4107GQ3	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TPCCA_0908	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TPCCA_0909	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TPCCA_0911	ENOG4105VM1	flagellar
TPCCA_0912	ENOG4105CPI	Metal Dependent Phosphohydrolase
TPCCA_0913	ENOG41082I4	UPF0102 protein
TPCCA_0917	ENOG4105CJW	magnesium transporter
TPCCA_0919	ENOG4105K63	Thioredoxin
TPCCA_0920	ENOG4108QUE	repeat-containing protein
TPCCA_0925	ENOG4108Z29	Flavodoxin
TPCCA_0926	ENOG4105C3F	Signal peptidase i
TPCCA_0930	ENOG4106SUR	Protein of unknown function DUF115
TPCCA_0931	ENOG4107MD5	glycoside hydrolase, family
TPCCA_0933	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TPCCA_0938	ENOG4106W1H	
TPCCA_0939	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TPCCA_0941	ENOG4106RHC	
TPCCA_0942	ENOG4106VWR	
TPCCA_0945	ENOG4105DJV	ribulose-phosphate 3-epimerase
TPCCA_0946	ENOG41083HS	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TPCCA_0947	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
TPCCA_0949	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TPCCA_0949a	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TPCCA_0950a	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TPCCA_0951	ENOG4105VG0	50S ribosomal protein l34
TPCCA_0956	ENOG41081IW	Inherit from COG: Membrane
TPCCA_0958	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TPCCA_0959	ENOG410680E	Flagellar protein
TPCCA_0960	ENOG4105CGA	flagellar basal-body rod protein FlgG
TPCCA_0961	ENOG4105CGA	flagellar basal-body rod protein FlgG
TPCCA_0963	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TPCCA_0964	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TPCCA_0965	ENOG410624X	efflux transporter, rnd family, mfp subunit
TPCCA_0966	ENOG4106KIQ	
TPCCA_0967	ENOG4106KIQ	
TPCCA_0971	ENOG4108SDV	Periplasmic Protein
TPCCA_0972	ENOG4107SJW	iron permease, FTR1
TPCCA_0973	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TPCCA_0974	ENOG4105ZAM	anti-sigma-28 factor flgm family protein
TPCCA_0975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TPCCA_0976	ENOG4106WPJ	
TPCCA_0977	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TPCCA_0978	ENOG410835P	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TPCCA_0979	ENOG4105F8V	Hydrolase, tatD family
TPCCA_0980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TPCCA_0981	ENOG4105BZU	Histidine kinase
TPCCA_0983	ENOG4105Y6R	
TPCCA_0984	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TPCCA_0985	ENOG4105C9M	aspartyl-trna synthetase
TPCCA_0988	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
TPCCA_0991	ENOG4105VCQ	rubredoxin
TPCCA_0993	ENOG4105K6T	rare lipoprotein A
TPCCA_0994	ENOG4105F8V	Hydrolase, tatD family
TPCCA_0997	ENOG4105D07	Signal peptide peptidase, SppA
TPCCA_0999	ENOG4105CNU	cell division protein FtsK
TPCCA_1001	ENOG4105TQV	
TPCCA_1003	ENOG4106SWD	
TPCCA_1004	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TPCCA_1005	ENOG4105C6E	dna polymerase iii
TPCCA_1006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TPCCA_1007	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TPCCA_1008	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TPCCA_1009	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TPCCA_1010	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TPCCA_1011	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TPCCA_1012	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TPCCA_1013	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TPCCA_1014	ENOG4106JWJ	
TPCCA_1015	ENOG4105M7K	Involved in the transcription termination process (By similarity)
TPCCA_1016	ENOG4107Z25	Basic membrane protein
TPCCA_1017	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TPCCA_1018	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TPCCA_1019	ENOG4107I15	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TPCCA_1020	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TPCCA_1021	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TPCCA_1022	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TPCCA_1023	ENOG410691R	Modulates RecA activity (By similarity)
TPCCA_1024	ENOG4108UJD	30S ribosomal protein S9
TPCCA_1025	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TPCCA_1027	ENOG4108I5U	Uridine phosphorylase
TPCCA_1028	ENOG4105C4R	Atp-dependent dna helicase
TPCCA_1029	ENOG41062BZ	domain protein
TPCCA_1032	ENOG41085BT	Protein of unknown function (DUF1312)
TPCCA_1033	ENOG4105D78	K07001 NTE family protein
TPCCA_1034	ENOG4105FEU	K -dependent Na -Ca exchanger
TPCCA_1035	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TPCCA_1037	ENOG4108UT2	hemolysin iii
TPCCA_1039	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TPCCA_1040	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TPCCA_1041	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)