locus-tag	class	description
HRQ91_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HRQ91_00010	COG0592	DNA-directed DNA polymerase activity
HRQ91_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HRQ91_00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HRQ91_00025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HRQ91_00030	COG0594	ribonuclease P activity
HRQ91_00035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HRQ91_00040	COG0706	membrane insertase activity
HRQ91_00045	COG1847	R3H domain protein
HRQ91_00055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HRQ91_00070	COG0561	phosphatase activity
HRQ91_00080	COG1192	Involved in chromosome partitioning
HRQ91_00085	COG1475	DNA binding
HRQ91_00090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HRQ91_00095	COG2188	Transcriptional regulator
HRQ91_00110	COG1979	alcohol dehydrogenase
HRQ91_00120	COG3845	ABC transporter
HRQ91_00125	COG4603	Belongs to the binding-protein-dependent transport system permease family
HRQ91_00130	COG1079	Belongs to the binding-protein-dependent transport system permease family
HRQ91_00140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRQ91_00165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_00165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_00175	COG0246	Mannitol dehydrogenase
HRQ91_00185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HRQ91_00220	COG0656	L-ascorbic acid biosynthetic process
HRQ91_00225	COG1639	'signal transduction protein
HRQ91_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HRQ91_00250	COG0564	pseudouridine synthase activity
HRQ91_00265	COG4536	flavin adenine dinucleotide binding
HRQ91_00270	COG4536	flavin adenine dinucleotide binding
HRQ91_00280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HRQ91_00285	COG1840	ABC-type Fe3 transport system, periplasmic component
HRQ91_00290	COG3842	ATPase activity
HRQ91_00305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HRQ91_00305	COG0140	phosphoribosyl-ATP diphosphatase activity
HRQ91_00310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HRQ91_00320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HRQ91_00340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HRQ91_00350	COG1640	4-alpha-glucanotransferase
HRQ91_00365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRQ91_00365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRQ91_00365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HRQ91_00380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HRQ91_00385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HRQ91_00390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HRQ91_00405	COG3830	Belongs to the UPF0237 family
HRQ91_00410	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HRQ91_00425	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HRQ91_00435	COG1704	LemA family
HRQ91_00445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HRQ91_00465	COG0488	(ABC) transporter
HRQ91_00470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HRQ91_00475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HRQ91_00490	COG0138	bifunctional purine biosynthesis protein purh
HRQ91_00500	COG1846	Transcriptional regulator
HRQ91_00515	COG1757	Na H antiporter
HRQ91_00545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HRQ91_00550	COG0492	ferredoxin-NADP+ reductase activity
HRQ91_00565	COG3118	belongs to the thioredoxin family
HRQ91_00575	COG0534	Mate efflux family protein
HRQ91_00605	COG0395	ABC-type sugar transport system, permease component
HRQ91_00615	COG0583	DNA-binding transcription factor activity
HRQ91_00630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRQ91_00630	COG0574	Belongs to the PEP-utilizing enzyme family
HRQ91_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRQ91_00640	COG0622	Phosphoesterase
HRQ91_00650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HRQ91_00655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HRQ91_00670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HRQ91_00670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HRQ91_00675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HRQ91_00680	COG1917	Cupin 2, conserved barrel domain protein
HRQ91_00700	COG1047	Peptidyl-prolyl cis-trans
HRQ91_00705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HRQ91_00725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HRQ91_00765	COG3885	ferrous iron binding
HRQ91_00765	COG2078	PFAM AMMECR1 domain protein
HRQ91_00775	COG1119	ATPase activity
HRQ91_00780	COG0038	chloride channel
HRQ91_00795	COG2848	UPF0210 protein
HRQ91_00800	COG0534	Mate efflux family protein
HRQ91_00815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HRQ91_00820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HRQ91_00825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HRQ91_00845	COG0564	pseudouridine synthase activity
HRQ91_00855	COG0071	Belongs to the small heat shock protein (HSP20) family
HRQ91_00865	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HRQ91_00880	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HRQ91_00885	COG0131	Imidazoleglycerol-phosphate dehydratase
HRQ91_00890	COG1640	4-alpha-glucanotransferase
HRQ91_00920	COG0826	peptidase U32
HRQ91_00925	COG0657	acetylesterase activity
HRQ91_00930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HRQ91_00940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HRQ91_00945	COG0445	tRNA wobble uridine modification
HRQ91_00950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRQ91_00950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HRQ91_00950	COG1013	pyruvate-flavodoxin oxidoreductase activity
HRQ91_00950	COG0674	pyruvate-flavodoxin oxidoreductase activity
HRQ91_00955	COG1940	carbohydrate kinase activity
HRQ91_00985	COG0673	inositol 2-dehydrogenase activity
HRQ91_01005	COG3119	arylsulfatase activity
HRQ91_01010	COG2188	Transcriptional regulator
HRQ91_01015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HRQ91_01080	COG1368	sulfuric ester hydrolase activity
HRQ91_01085	COG1970	mechanosensitive ion channel activity
HRQ91_01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRQ91_01095	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_01100	COG0371	Dehydrogenase
HRQ91_01115	COG3842	ATPase activity
HRQ91_01125	COG2337	Toxic component of a toxin-antitoxin (TA) module
HRQ91_01145	COG2315	Protein conserved in bacteria
HRQ91_01150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRQ91_01155	COG1120	ATPase activity
HRQ91_01195	COG1132	(ABC) transporter
HRQ91_01200	COG1132	(ABC) transporter
HRQ91_01200	COG2375	cellular response to nickel ion
HRQ91_01210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HRQ91_01215	COG1116	anion transmembrane transporter activity
HRQ91_01230	COG3041	Addiction module toxin RelE StbE family
HRQ91_01250	COG3328	transposase activity
HRQ91_01280	COG3340	Belongs to the peptidase S51 family
HRQ91_01310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HRQ91_01315	COG0246	Mannitol dehydrogenase
HRQ91_01320	COG1802	Transcriptional regulator
HRQ91_01330	COG1078	dGTPase activity
HRQ91_01350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRQ91_01360	COG0840	transmembrane signaling receptor activity
HRQ91_01365	COG3804	dihydrodipicolinate reductase
HRQ91_01370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HRQ91_01385	COG0039	L-malate dehydrogenase activity
HRQ91_01415	COG0205	6-phosphofructokinase activity
HRQ91_01425	COG0840	transmembrane signaling receptor activity
HRQ91_01430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HRQ91_01435	COG0248	Ppx GppA phosphatase
HRQ91_01460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HRQ91_01470	COG1045	serine acetyltransferase
HRQ91_01480	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HRQ91_01505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HRQ91_01515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HRQ91_01520	COG0250	Participates in transcription elongation, termination and antitermination
HRQ91_01525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HRQ91_01530	COG0081	regulation of translation
HRQ91_01535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HRQ91_01545	COG0085	RNA polymerase activity
HRQ91_01555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HRQ91_01560	COG0049	tRNA binding
HRQ91_01565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HRQ91_01570	COG0051	transcription antitermination factor activity, RNA binding
HRQ91_01575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HRQ91_01580	COG0088	Forms part of the polypeptide exit tunnel
HRQ91_01585	COG0089	rRNA binding
HRQ91_01590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HRQ91_01595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HRQ91_01600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HRQ91_01605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HRQ91_01615	COG0255	Belongs to the universal ribosomal protein uL29 family
HRQ91_01620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HRQ91_01625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HRQ91_01630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HRQ91_01635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HRQ91_01640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HRQ91_01645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HRQ91_01650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HRQ91_01660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HRQ91_01665	COG1841	ribosomal large subunit assembly
HRQ91_01670	COG0200	Binds to the 23S rRNA
HRQ91_01680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HRQ91_01690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HRQ91_01695	COG0202	RNA polymerase activity
HRQ91_01700	COG0203	ribosomal protein L17
HRQ91_01715	COG0559	Belongs to the binding-protein-dependent transport system permease family
HRQ91_01735	COG0517	IMP dehydrogenase activity
HRQ91_01745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HRQ91_01750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HRQ91_01755	COG0455	bacterial-type flagellum organization
HRQ91_01760	COG0793	Belongs to the peptidase S41A family
HRQ91_01805	COG3328	transposase activity
HRQ91_01840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HRQ91_01850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HRQ91_01875	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_01880	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HRQ91_01890	COG0058	SHG alpha-glucan phosphorylase activity
HRQ91_01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRQ91_01920	COG0765	amino acid transport
HRQ91_01925	COG1126	abc transporter atp-binding protein
HRQ91_01930	COG0659	secondary active sulfate transmembrane transporter activity
HRQ91_01940	COG0534	Mate efflux family protein
HRQ91_01945	COG2186	Transcriptional regulator
HRQ91_01955	COG3959	Transketolase, thiamine diphosphate binding domain
HRQ91_01960	COG3958	Transketolase
HRQ91_01965	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HRQ91_01970	COG0488	(ABC) transporter
HRQ91_01980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HRQ91_01995	COG2873	o-acetylhomoserine
HRQ91_02005	COG1012	belongs to the aldehyde dehydrogenase family
HRQ91_02005	COG1454	alcohol dehydrogenase
HRQ91_02020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HRQ91_02025	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_02030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HRQ91_02035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HRQ91_02045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HRQ91_02045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HRQ91_02050	COG0613	PHP domain protein
HRQ91_02095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRQ91_02110	COG4443	Transcriptional Coactivator p15 (PC4)
HRQ91_02120	COG1652	LysM domain
HRQ91_02125	COG0494	nUDIX hydrolase
HRQ91_02135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HRQ91_02160	COG4667	esterase of the alpha-beta hydrolase superfamily
HRQ91_02170	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HRQ91_02175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HRQ91_02180	COG1802	Transcriptional regulator
HRQ91_02195	COG0559	Belongs to the binding-protein-dependent transport system permease family
HRQ91_02220	COG1473	amidohydrolase
HRQ91_02225	COG3681	Belongs to the UPF0597 family
HRQ91_02230	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_02235	COG0783	Belongs to the Dps family
HRQ91_02250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRQ91_02255	COG2166	iron-sulfur cluster assembly
HRQ91_02270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_02280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_02280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_02305	COG1487	ribonuclease activity
HRQ91_02320	COG0501	Belongs to the peptidase M48B family
HRQ91_02340	COG1175	transmembrane transport
HRQ91_02355	COG1283	sodium-dependent phosphate transmembrane transporter activity
HRQ91_02370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRQ91_02375	COG0724	RNA recognition motif
HRQ91_02385	COG0740	serine-type endopeptidase activity
HRQ91_02405	COG3956	TIGRFAM MazG family protein
HRQ91_02410	COG0193	aminoacyl-tRNA hydrolase activity
HRQ91_02415	COG2217	Heavy metal translocating P-type atpase
HRQ91_02420	COG0640	Transcriptional regulator
HRQ91_02440	COG1131	(ABC) transporter
HRQ91_02445	COG3177	Filamentation induced by cAMP protein fic
HRQ91_02455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HRQ91_02460	COG2703	oxygen carrier activity
HRQ91_02465	COG2342	PFAM TM1410 hypothetical-related protein
HRQ91_02490	COG4948	Mandelate Racemase Muconate Lactonizing
HRQ91_02495	COG1349	DNA-binding transcription factor activity
HRQ91_02500	COG0322	excinuclease ABC activity
HRQ91_02515	COG0006	proline dipeptidase activity
HRQ91_02520	COG0728	peptidoglycan biosynthetic process
HRQ91_02570	COG0811	peptide transport
HRQ91_02575	COG0848	biopolymer transport protein
HRQ91_02605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HRQ91_02605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HRQ91_02615	COG2885	chlorophyll binding
HRQ91_02630	COG1177	transmembrane transport
HRQ91_02635	COG1176	ABC-type spermidine putrescine transport system, permease component I
HRQ91_02640	COG3842	ATPase activity
HRQ91_02650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HRQ91_02660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HRQ91_02680	COG0616	signal peptide processing
HRQ91_02695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRQ91_02700	COG0352	thiamine-phosphate diphosphorylase activity
HRQ91_02725	COG1418	mRNA catabolic process
HRQ91_02730	COG1137	ATPase activity
HRQ91_02745	COG0504	CTP synthase activity
HRQ91_02755	COG2201	protein-glutamate methylesterase activity
HRQ91_02775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HRQ91_02780	COG0739	heme binding
HRQ91_02790	COG1595	DNA-templated transcription, initiation
HRQ91_02810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HRQ91_02830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HRQ91_02835	COG2011	ABC-type metal ion transport system permease component
HRQ91_02845	COG2878	Part of a membrane complex involved in electron transport
HRQ91_02850	COG4657	Part of a membrane complex involved in electron transport
HRQ91_02855	COG4660	Part of a membrane complex involved in electron transport
HRQ91_02865	COG4658	electron transport chain
HRQ91_02870	COG4656	Part of a membrane complex involved in electron transport
HRQ91_02900	COG1397	ADP-ribosylglycohydrolase
HRQ91_02915	COG1373	ATPase (AAA superfamily
HRQ91_02920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HRQ91_02940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HRQ91_02950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HRQ91_02955	COG2203	Gaf domain
HRQ91_02955	COG3706	GGDEF domain
HRQ91_02955	COG4251	negative regulation of phosphorylation
HRQ91_02955	COG5001	Diguanylate cyclase
HRQ91_02960	COG1862	Preprotein translocase
HRQ91_02965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRQ91_02970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HRQ91_02975	COG1063	alcohol dehydrogenase
HRQ91_02980	COG1063	alcohol dehydrogenase
HRQ91_02985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_02995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_03000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HRQ91_03005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HRQ91_03050	COG0826	peptidase U32
HRQ91_03065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HRQ91_03085	COG1929	Belongs to the glycerate kinase type-1 family
HRQ91_03090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HRQ91_03100	COG0330	HflC and HflK could
HRQ91_03105	COG0330	HflC and HflK could
HRQ91_03110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HRQ91_03120	COG0523	cobalamin synthesis protein
HRQ91_03135	COG0137	argininosuccinate synthase activity
HRQ91_03145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HRQ91_03160	COG0840	transmembrane signaling receptor activity
HRQ91_03170	COG4120	Belongs to the binding-protein-dependent transport system permease family
HRQ91_03175	COG1122	ATPase activity
HRQ91_03180	COG0423	glycine-tRNA ligase activity
HRQ91_03200	COG0768	penicillin binding
HRQ91_03205	COG0681	Belongs to the peptidase S26 family
HRQ91_03210	COG0739	heme binding
HRQ91_03225	COG1686	Belongs to the peptidase S11 family
HRQ91_03230	COG2252	PERMEase
HRQ91_03235	COG0191	fructose-bisphosphate aldolase activity
HRQ91_03255	COG0084	hydrolase, TatD family'
HRQ91_03260	COG1438	arginine binding
HRQ91_03265	COG1193	negative regulation of DNA recombination
HRQ91_03275	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HRQ91_03290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HRQ91_03305	COG0601	transmembrane transport
HRQ91_03320	COG2217	Heavy metal translocating P-type atpase
HRQ91_03325	COG1937	Protein conserved in bacteria
HRQ91_03340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HRQ91_03355	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HRQ91_03370	COG3845	ABC transporter
HRQ91_03375	COG1744	ABC transporter substrate-binding protein PnrA-like
HRQ91_03400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HRQ91_03400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HRQ91_03400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRQ91_03435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HRQ91_03440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRQ91_03445	COG0450	alkyl hydroperoxide reductase
HRQ91_03450	COG0492	ferredoxin-NADP+ reductase activity
HRQ91_03490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRQ91_03495	COG0473	3-isopropylmalate dehydrogenase activity
HRQ91_03535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HRQ91_03540	COG4948	Mandelate Racemase Muconate Lactonizing
HRQ91_03545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_03555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_03560	COG1879	ABC-type sugar transport system periplasmic component
HRQ91_03565	COG1129	ABC transporter
HRQ91_03575	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRQ91_03635	COG3842	ATPase activity
HRQ91_03660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HRQ91_03680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HRQ91_03705	COG0653	protein targeting
HRQ91_03735	COG1464	Belongs to the NlpA lipoprotein family
HRQ91_03745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRQ91_03745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRQ91_03745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRQ91_03755	COG0564	pseudouridine synthase activity
HRQ91_03775	COG0779	Required for maturation of 30S ribosomal subunits
HRQ91_03785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HRQ91_03790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HRQ91_03795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HRQ91_03800	COG0196	riboflavin kinase activity
HRQ91_03805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HRQ91_03810	COG1185	polyribonucleotide nucleotidyltransferase activity
HRQ91_03815	COG0756	dUTP diphosphatase activity
HRQ91_03830	COG0343	queuine tRNA-ribosyltransferase activity
HRQ91_03845	COG0280	phosphate acetyltransferase
HRQ91_03885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HRQ91_03900	COG0800	Aldolase
HRQ91_03905	COG1199	ATP-dependent helicase activity
HRQ91_03930	COG0395	ABC-type sugar transport system, permease component
HRQ91_03935	COG2182	Extracellular solute-binding protein
HRQ91_03945	COG0268	Binds directly to 16S ribosomal RNA
HRQ91_03955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HRQ91_03965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HRQ91_03970	COG1609	Transcriptional regulator
HRQ91_03980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_04010	COG1131	(ABC) transporter
HRQ91_04015	COG2801	Transposase and inactivated derivatives
HRQ91_04035	COG0513	Belongs to the DEAD box helicase family
HRQ91_04040	COG0488	(ABC) transporter
HRQ91_04045	COG0210	DNA helicase
HRQ91_04070	COG1104	cysteine desulfurase activity
HRQ91_04075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HRQ91_04085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HRQ91_04095	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRQ91_04105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HRQ91_04110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HRQ91_04115	COG0835	chemotaxis
HRQ91_04125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HRQ91_04130	COG0497	DNA recombination
HRQ91_04140	COG1744	ABC transporter substrate-binding protein PnrA-like
HRQ91_04145	COG3845	ABC transporter
HRQ91_04150	COG4603	Belongs to the binding-protein-dependent transport system permease family
HRQ91_04155	COG1079	Belongs to the binding-protein-dependent transport system permease family
HRQ91_04170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HRQ91_04175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRQ91_04180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HRQ91_04200	COG2001	Belongs to the MraZ family
HRQ91_04205	COG0275	rRNA processing
HRQ91_04215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HRQ91_04220	COG0772	Belongs to the SEDS family
HRQ91_04250	COG0758	DNA mediated transformation
HRQ91_04250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HRQ91_04255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HRQ91_04255	COG0551	DNA topoisomerase type I activity
HRQ91_04260	COG4974	Belongs to the 'phage' integrase family
HRQ91_04265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HRQ91_04270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HRQ91_04305	COG0248	Ppx GppA phosphatase
HRQ91_04305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HRQ91_04315	COG0583	DNA-binding transcription factor activity
HRQ91_04320	COG1766	The M ring may be actively involved in energy transduction
HRQ91_04330	COG1317	bacterial-type flagellum organization
HRQ91_04335	COG1157	protein secretion by the type III secretion system
HRQ91_04345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HRQ91_04350	COG2084	Dehydrogenase
HRQ91_04375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HRQ91_04385	COG1702	phosphate starvation-inducible protein PhoH
HRQ91_04390	COG1480	7TM receptor with intracellular HD hydrolase
HRQ91_04395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HRQ91_04430	COG0552	protein localization to endoplasmic reticulum
HRQ91_04440	COG4591	ABC-type transport system involved in lipoprotein release permease component
HRQ91_04445	COG1136	(ABC) transporter
HRQ91_04460	COG3869	Catalyzes the specific phosphorylation of arginine residues in
HRQ91_04470	COG3977	Valine--pyruvate aminotransferase
HRQ91_04475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HRQ91_04485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HRQ91_04495	COG1904	glucuronate isomerase
HRQ91_04500	COG0670	Belongs to the BI1 family
HRQ91_04505	COG0006	proline dipeptidase activity
HRQ91_04515	COG1966	Carbon starvation protein
HRQ91_04525	COG1373	ATPase (AAA superfamily
HRQ91_04555	COG0626	cystathionine gamma-synthase activity
HRQ91_04560	COG2832	Protein of unknown function (DUF454)
HRQ91_04565	COG1132	(ABC) transporter
HRQ91_04570	COG4988	ABC transporter
HRQ91_04590	COG0848	biopolymer transport protein
HRQ91_04650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HRQ91_04670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HRQ91_04675	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_04690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_04715	COG1234	tRNA 3'-trailer cleavage
HRQ91_04725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HRQ91_04750	COG1136	(ABC) transporter
HRQ91_04760	COG0632	four-way junction helicase activity
HRQ91_04765	COG2255	four-way junction helicase activity
HRQ91_04770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HRQ91_04790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HRQ91_04820	COG1366	Belongs to the anti-sigma-factor antagonist family
HRQ91_04845	COG2972	Histidine kinase
HRQ91_04850	COG2207	Transcriptional regulator
HRQ91_04860	COG1175	transmembrane transport
HRQ91_04865	COG3833	ABC-type maltose transport systems, permease component
HRQ91_04875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HRQ91_04880	COG1722	exodeoxyribonuclease VII activity
HRQ91_04885	COG1570	exodeoxyribonuclease VII activity
HRQ91_04890	COG0731	radical SAM domain protein
HRQ91_04900	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HRQ91_04910	COG1388	LysM domain
HRQ91_04910	COG0860	N-Acetylmuramoyl-L-alanine amidase
HRQ91_04940	COG1904	glucuronate isomerase
HRQ91_04945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_04955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_04960	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_04965	COG0473	3-isopropylmalate dehydrogenase activity
HRQ91_04965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRQ91_04970	COG1312	Catalyzes the dehydration of D-mannonate
HRQ91_04980	COG1940	carbohydrate kinase activity
HRQ91_04990	COG4213	ABC transporter substrate-binding protein
HRQ91_05000	COG4214	carbohydrate transport
HRQ91_05010	COG3330	Domain of unknown function (DUF4912)
HRQ91_05060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRQ91_05090	COG4209	transmembrane transport
HRQ91_05095	COG0395	ABC-type sugar transport system, permease component
HRQ91_05125	COG0730	response to heat
HRQ91_05140	COG0666	response to abiotic stimulus
HRQ91_05145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HRQ91_05155	COG0470	DNA polymerase III
HRQ91_05160	COG3852	Histidine kinase
HRQ91_05165	COG2204	response regulator
HRQ91_05170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HRQ91_05175	COG4786	Flagellar basal body rod
HRQ91_05215	COG3706	GGDEF domain
HRQ91_05225	COG2348	transferase activity, transferring amino-acyl groups
HRQ91_05270	COG0747	negative chemotaxis
HRQ91_05280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HRQ91_05285	COG0444	Belongs to the ABC transporter superfamily
HRQ91_05290	COG4608	Belongs to the ABC transporter superfamily
HRQ91_05300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HRQ91_05310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HRQ91_05315	COG0285	dihydrofolate synthase activity
HRQ91_05320	COG0180	Tryptophanyl-tRNA synthetase
HRQ91_05325	COG0617	tRNA 3'-terminal CCA addition
HRQ91_05365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HRQ91_05370	COG0358	DNA primase activity
HRQ91_05375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HRQ91_05395	COG1077	Cell shape determining protein MreB Mrl
HRQ91_05410	COG0768	penicillin binding
HRQ91_05415	COG0772	Belongs to the SEDS family
HRQ91_05425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HRQ91_05460	COG0813	purine-nucleoside phosphorylase activity
HRQ91_05470	COG1482	cell wall glycoprotein biosynthetic process
HRQ91_05475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRQ91_05480	COG0217	transcriptional regulatory protein
HRQ91_05485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HRQ91_05505	COG0297	glycogen (starch) synthase activity
HRQ91_05515	COG0750	zinc metalloprotease
HRQ91_05520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HRQ91_05525	COG4589	Belongs to the CDS family
HRQ91_05530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HRQ91_05535	COG0233	cytoplasmic translational termination
HRQ91_05540	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HRQ91_05545	COG0052	Belongs to the universal ribosomal protein uS2 family
HRQ91_05550	COG0424	maF-like protein
HRQ91_05560	COG1413	lyase activity
HRQ91_05570	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HRQ91_05575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HRQ91_05585	COG0571	ribonuclease III activity
HRQ91_05605	COG1234	tRNA 3'-trailer cleavage
HRQ91_05635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HRQ91_05640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HRQ91_05655	COG0564	pseudouridine synthase activity
HRQ91_05665	COG1882	Formate acetyltransferase
HRQ91_05670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HRQ91_05675	COG1070	Carbohydrate kinase
HRQ91_05675	COG4806	L-rhamnose isomerase
HRQ91_05680	COG1129	ABC transporter
HRQ91_05685	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRQ91_05690	COG1879	ABC-type sugar transport system periplasmic component
HRQ91_05745	COG1151	hydroxylamine reductase activity
HRQ91_05760	COG0395	ABC-type sugar transport system, permease component
HRQ91_05765	COG1175	transmembrane transport
HRQ91_05775	COG4948	Mandelate Racemase Muconate Lactonizing
HRQ91_05780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HRQ91_05785	COG0460	homoserine dehydrogenase
HRQ91_05785	COG0527	aspartate kinase activity
HRQ91_05790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HRQ91_05795	COG3842	ATPase activity
HRQ91_05800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRQ91_05810	COG2207	Transcriptional regulator
HRQ91_05810	COG4753	response regulator
HRQ91_05815	COG2972	Histidine kinase
HRQ91_05820	COG1653	transport
HRQ91_05825	COG1175	transmembrane transport
HRQ91_05830	COG0395	ABC-type sugar transport system, permease component
HRQ91_05835	COG1486	melibiose metabolic process
HRQ91_05840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HRQ91_05850	COG2814	Major facilitator Superfamily
HRQ91_05910	COG0617	tRNA 3'-terminal CCA addition
HRQ91_05920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HRQ91_05925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HRQ91_05950	COG1691	(AIR) carboxylase
HRQ91_05970	COG3386	PFAM SMP-30 Gluconolaconase
HRQ91_05975	COG3958	Transketolase
HRQ91_05980	COG3959	Transketolase, thiamine diphosphate binding domain
HRQ91_05995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRQ91_06005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HRQ91_06010	COG3711	transcriptional antiterminator
HRQ91_06050	COG0305	Participates in initiation and elongation during chromosome replication
HRQ91_06060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HRQ91_06065	COG0629	single-stranded DNA binding
HRQ91_06070	COG0360	Binds together with S18 to 16S ribosomal RNA
HRQ91_06100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HRQ91_06110	COG1102	Psort location Cytoplasmic, score
HRQ91_06115	COG0426	domain, Protein
HRQ91_06155	COG0463	Glycosyl transferase, family 2
HRQ91_06180	COG0706	membrane insertase activity
HRQ91_06225	COG3118	belongs to the thioredoxin family
HRQ91_06230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HRQ91_06240	COG1269	ATP hydrolysis coupled proton transport
HRQ91_06245	COG1394	ATPase activity, coupled to movement of substances
HRQ91_06250	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HRQ91_06255	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HRQ91_06265	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
HRQ91_06290	COG1191	sigma factor activity
HRQ91_06305	COG1419	protein localization to endoplasmic reticulum
HRQ91_06310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HRQ91_06315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HRQ91_06320	COG1684	flagellar biosynthetic protein fliR
HRQ91_06325	COG1987	bacterial-type flagellum assembly
HRQ91_06330	COG1338	Plays a role in the flagellum-specific transport system
HRQ91_06345	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRQ91_06350	COG1580	Controls the rotational direction of flagella during chemotaxis
HRQ91_06355	COG1360	Flagellar Motor Protein
HRQ91_06370	COG0745	RESPONSE REGULATOR receiver
HRQ91_06375	COG5002	protein histidine kinase activity
HRQ91_06380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HRQ91_06390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HRQ91_06400	COG0009	L-threonylcarbamoyladenylate synthase
HRQ91_06440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HRQ91_06450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HRQ91_06460	COG3549	Plasmid maintenance system killer
HRQ91_06520	COG1022	Amp-dependent synthetase and ligase
HRQ91_06530	COG0301	tRNA thio-modification
HRQ91_06550	COG0438	transferase activity, transferring glycosyl groups
HRQ91_06555	COG1573	uracil-dna glycosylase
HRQ91_06560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HRQ91_06565	COG0101	tRNA pseudouridine synthase activity
HRQ91_06575	COG0736	holo-[acyl-carrier-protein] synthase activity
HRQ91_06585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HRQ91_06590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HRQ91_06595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HRQ91_06600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HRQ91_06610	COG3976	FMN-binding domain protein
HRQ91_06610	COG1053	succinate dehydrogenase
HRQ91_06620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HRQ91_06625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HRQ91_06625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HRQ91_06630	COG0739	heme binding
HRQ91_06640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HRQ91_06645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HRQ91_06660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HRQ91_06675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HRQ91_06680	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HRQ91_06685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HRQ91_06690	COG1268	BioY protein
HRQ91_06695	COG1122	ATPase activity
HRQ91_06700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HRQ91_06710	COG0673	inositol 2-dehydrogenase activity
HRQ91_06715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HRQ91_06740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HRQ91_06760	COG4821	SIS domain
HRQ91_06795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HRQ91_06835	COG0802	atpase or kinase
HRQ91_06840	COG1214	PFAM Peptidase M22, glycoprotease
HRQ91_06850	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HRQ91_06855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HRQ91_06900	COG0544	peptidyl-prolyl cis-trans isomerase activity
HRQ91_06905	COG0740	serine-type endopeptidase activity
HRQ91_06910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HRQ91_06915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HRQ91_06925	COG4565	transcriptional regulatory protein
HRQ91_06930	COG3290	protein histidine kinase activity
HRQ91_06940	COG4149	molybdate abc transporter
HRQ91_06945	COG3842	ATPase activity
HRQ91_06960	COG4806	L-rhamnose isomerase
HRQ91_06965	COG0436	Aminotransferase
HRQ91_06970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HRQ91_06975	COG0396	ATPase activity
HRQ91_06985	COG0719	Fe-S assembly protein
HRQ91_06995	COG0537	adenosine 5'-monophosphoramidase activity
HRQ91_07005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_07015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_07015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_07020	COG0579	oxidoreductase
HRQ91_07045	COG3681	Belongs to the UPF0597 family
HRQ91_07065	COG1349	DNA-binding transcription factor activity
HRQ91_07070	COG1012	belongs to the aldehyde dehydrogenase family
HRQ91_07075	COG0534	Mate efflux family protein
HRQ91_07085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HRQ91_07100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HRQ91_07130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HRQ91_07140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HRQ91_07145	COG1070	Carbohydrate kinase
HRQ91_07150	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRQ91_07155	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRQ91_07160	COG1129	ABC transporter
HRQ91_07175	COG1349	DNA-binding transcription factor activity
HRQ91_07180	COG1132	(ABC) transporter
HRQ91_07185	COG1132	(ABC) transporter
HRQ91_07190	COG1309	transcriptional regulator
HRQ91_07200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HRQ91_07205	COG0419	ATPase involved in DNA repair
HRQ91_07210	COG0420	3'-5' exonuclease activity
HRQ91_07225	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HRQ91_07240	COG0542	response to heat
HRQ91_07260	COG0557	exoribonuclease II activity
HRQ91_07285	COG0588	phosphoglycerate mutase activity
HRQ91_07290	COG2226	methyltransferase
HRQ91_07325	COG0733	neurotransmitter:sodium symporter activity
HRQ91_07335	COG1082	Xylose isomerase domain protein TIM barrel
HRQ91_07340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HRQ91_07345	COG1070	Carbohydrate kinase
HRQ91_07350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HRQ91_07355	COG2373	Large extracellular alpha-helical protein
HRQ91_07360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRQ91_07370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_07390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HRQ91_07410	COG1120	ATPase activity
HRQ91_07415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRQ91_07420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRQ91_07430	COG0500	methyltransferase
HRQ91_07435	COG3708	Transcriptional regulator
HRQ91_07435	COG2207	Transcriptional regulator
HRQ91_07460	COG2972	Histidine kinase
HRQ91_07470	COG1840	ABC-type Fe3 transport system, periplasmic component
HRQ91_07490	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HRQ91_07520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HRQ91_07530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HRQ91_07535	COG2089	acid synthase
HRQ91_07540	COG0124	histidyl-tRNA synthetase
HRQ91_07560	COG2604	Protein of unknown function DUF115
HRQ91_07565	COG0481	GTPase activity
HRQ91_07570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRQ91_07580	COG0037	tRNA processing
HRQ91_07585	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HRQ91_07600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HRQ91_07630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRQ91_07635	COG1979	alcohol dehydrogenase
HRQ91_07640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRQ91_07645	COG0431	NADPH-dependent FMN reductase
HRQ91_07645	COG1053	succinate dehydrogenase
HRQ91_07645	COG3976	FMN-binding domain protein
HRQ91_07650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HRQ91_07665	COG1773	rubredoxin
HRQ91_07665	COG1592	Rubrerythrin
HRQ91_07685	COG4608	Belongs to the ABC transporter superfamily
HRQ91_07690	COG0444	Belongs to the ABC transporter superfamily
HRQ91_07695	COG0601	transmembrane transport
HRQ91_07715	COG0018	arginyl-trna synthetase
HRQ91_07765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HRQ91_07775	COG0335	large ribosomal subunit rRNA binding
HRQ91_07780	COG0336	Belongs to the RNA methyltransferase TrmD family
HRQ91_07785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HRQ91_07790	COG1837	Belongs to the UPF0109 family
HRQ91_07800	COG0085	RNA polymerase activity
HRQ91_07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRQ91_07870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HRQ91_07885	COG3177	Filamentation induced by cAMP protein fic
HRQ91_07890	COG0028	Belongs to the TPP enzyme family
HRQ91_07895	COG0129	dihydroxy-acid dehydratase activity
HRQ91_07925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HRQ91_07940	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HRQ91_07945	COG1671	Belongs to the UPF0178 family
HRQ91_07950	COG0784	Response regulator, receiver
HRQ91_07950	COG3437	response regulator, receiver
HRQ91_07955	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HRQ91_07955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HRQ91_07980	COG0674	pyruvate-flavodoxin oxidoreductase activity
HRQ91_07980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HRQ91_07980	COG1013	pyruvate-flavodoxin oxidoreductase activity
HRQ91_07980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRQ91_07995	COG0426	domain, Protein
HRQ91_07995	COG1773	rubredoxin
HRQ91_08000	COG4221	oxidoreductase activity
HRQ91_08005	COG0037	tRNA processing
HRQ91_08010	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HRQ91_08015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HRQ91_08025	COG2201	protein-glutamate methylesterase activity
HRQ91_08035	COG0835	chemotaxis
HRQ91_08040	COG0643	Histidine kinase
HRQ91_08040	COG2198	Histidine kinase
HRQ91_08050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HRQ91_08055	COG0436	Aminotransferase
HRQ91_08060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HRQ91_08075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HRQ91_08095	COG0475	glutathione-regulated potassium exporter activity
HRQ91_08105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HRQ91_08135	COG1053	succinate dehydrogenase
HRQ91_08135	COG3976	FMN-binding domain protein
HRQ91_08140	COG1196	nuclear chromosome segregation
HRQ91_08160	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HRQ91_08180	COG1373	ATPase (AAA superfamily
HRQ91_08205	COG2233	PERMEase
HRQ91_08210	COG0114	fumarate hydratase activity
HRQ91_08220	COG0525	valine-tRNA ligase activity
HRQ91_08275	COG1840	ABC-type Fe3 transport system, periplasmic component
HRQ91_08300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HRQ91_08305	COG4115	mRNA cleavage
HRQ91_08325	COG1509	lysine 2,3-aminomutase activity
HRQ91_08335	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HRQ91_08340	COG1187	pseudouridine synthase activity
HRQ91_08345	COG0372	Belongs to the citrate synthase family
HRQ91_08350	COG0024	Methionine aminopeptidase
HRQ91_08355	COG0484	heat shock protein binding
HRQ91_08365	COG1940	carbohydrate kinase activity
HRQ91_08385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HRQ91_08390	COG1063	alcohol dehydrogenase
HRQ91_08395	COG1394	ATPase activity, coupled to movement of substances
HRQ91_08400	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HRQ91_08405	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HRQ91_08425	COG1269	ATP hydrolysis coupled proton transport
HRQ91_08445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HRQ91_08450	COG0149	triose-phosphate isomerase activity
HRQ91_08455	COG0126	phosphoglycerate kinase activity
HRQ91_08460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HRQ91_08465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_08480	COG1609	Transcriptional regulator
HRQ91_08485	COG0363	glucosamine-6-phosphate deaminase activity
HRQ91_08510	COG3604	Transcriptional regulator
HRQ91_08515	COG0539	negative regulation of cytoplasmic translation
HRQ91_08525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HRQ91_08530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HRQ91_08540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HRQ91_08560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HRQ91_08570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HRQ91_08570	COG1747	RNA polymerase binding
HRQ91_08575	COG0708	Exodeoxyribonuclease III
HRQ91_08600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HRQ91_08640	COG1088	dTDP-glucose 4,6-dehydratase activity
HRQ91_08665	COG0110	maltose O-acetyltransferase activity
HRQ91_08675	COG3754	Rhamnan synthesis protein F
HRQ91_08680	COG0110	maltose O-acetyltransferase activity
HRQ91_08690	COG3958	Transketolase
HRQ91_08695	COG3959	Transketolase, thiamine diphosphate binding domain
HRQ91_08700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HRQ91_08710	COG0028	Belongs to the TPP enzyme family
HRQ91_08735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HRQ91_08740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HRQ91_08765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRQ91_08775	COG0395	ABC-type sugar transport system, permease component
HRQ91_08780	COG1175	transmembrane transport
HRQ91_08790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HRQ91_08820	COG0148	phosphopyruvate hydratase activity
HRQ91_08830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HRQ91_08835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HRQ91_08840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HRQ91_08845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HRQ91_08855	COG4452	Inner membrane protein CreD
HRQ91_08860	COG0840	transmembrane signaling receptor activity
HRQ91_08865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HRQ91_08890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HRQ91_08895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HRQ91_08900	COG0215	cysteine-tRNA ligase activity
HRQ91_08920	COG0528	UMP kinase activity
HRQ91_08930	COG2003	Belongs to the UPF0758 family
HRQ91_08940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HRQ91_08945	COG0556	nucleotide-excision repair
HRQ91_08950	COG1120	ATPase activity
HRQ91_08955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HRQ91_08985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HRQ91_08990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_08990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_09005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HRQ91_09015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HRQ91_09030	COG1349	DNA-binding transcription factor activity
HRQ91_09050	COG0395	ABC-type sugar transport system, permease component
HRQ91_09055	COG1175	transmembrane transport
HRQ91_09070	COG0395	ABC-type sugar transport system, permease component
HRQ91_09075	COG1175	transmembrane transport
HRQ91_09100	COG3290	protein histidine kinase activity
HRQ91_09100	COG0840	transmembrane signaling receptor activity
HRQ91_09125	COG1609	Transcriptional regulator
HRQ91_09130	COG1609	Transcriptional regulator
HRQ91_09135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HRQ91_09140	COG1882	Formate acetyltransferase
HRQ91_09165	COG0656	L-ascorbic acid biosynthetic process
HRQ91_09170	COG1739	Uncharacterized protein family UPF0029
HRQ91_09190	COG0495	leucyl-tRNA aminoacylation
HRQ91_09205	COG1366	Belongs to the anti-sigma-factor antagonist family
HRQ91_09220	COG0484	heat shock protein binding
HRQ91_09230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRQ91_09235	COG0564	pseudouridine synthase activity
HRQ91_09255	COG0563	adenylate kinase activity
HRQ91_09265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRQ91_09280	COG1129	ABC transporter
HRQ91_09285	COG1122	ATPase activity
HRQ91_09305	COG0513	Belongs to the DEAD box helicase family
HRQ91_09310	COG1132	(ABC) transporter
HRQ91_09340	COG2375	cellular response to nickel ion
HRQ91_09340	COG1132	(ABC) transporter
HRQ91_09345	COG4977	sequence-specific DNA binding
HRQ91_09345	COG1917	Cupin 2, conserved barrel domain protein
HRQ91_09360	COG1132	(ABC) transporter
HRQ91_09365	COG1132	(ABC) transporter
HRQ91_09395	COG1846	Transcriptional regulator
HRQ91_09405	COG1469	GTP cyclohydrolase I activity
HRQ91_09410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HRQ91_09435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HRQ91_09440	COG1830	Aldolase
HRQ91_09445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_09445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_09450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_09460	COG0235	Class ii aldolase
HRQ91_09470	COG1349	DNA-binding transcription factor activity
HRQ91_09480	COG0154	amidase activity
HRQ91_09490	COG0017	Asparaginyl-tRNA synthetase
HRQ91_09495	COG0504	CTP synthase activity
HRQ91_09505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HRQ91_09510	COG0564	pseudouridine synthase activity
HRQ91_09520	COG0765	amino acid transport
HRQ91_09525	COG1126	abc transporter atp-binding protein
HRQ91_09530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HRQ91_09535	COG0534	Mate efflux family protein
HRQ91_09540	COG3177	Filamentation induced by cAMP protein fic
HRQ91_09550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HRQ91_09555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HRQ91_09560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HRQ91_09570	COG1070	Carbohydrate kinase
HRQ91_09575	COG2115	Belongs to the xylose isomerase family
HRQ91_09590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HRQ91_09595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRQ91_09600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRQ91_09605	COG1121	(ABC) transporter
HRQ91_09610	COG0803	Belongs to the bacterial solute-binding protein 9 family
HRQ91_09645	COG1373	ATPase (AAA superfamily
HRQ91_09655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HRQ91_09660	COG0107	imidazoleglycerol-phosphate synthase activity
HRQ91_09670	COG0720	synthase
HRQ91_09675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HRQ91_09680	COG1181	Belongs to the D-alanine--D-alanine ligase family
HRQ91_09685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HRQ91_09700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HRQ91_09705	COG0724	RNA recognition motif
HRQ91_09735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HRQ91_09745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HRQ91_09770	COG2885	chlorophyll binding
HRQ91_09780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HRQ91_09785	COG1121	(ABC) transporter
HRQ91_09805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HRQ91_09815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HRQ91_09820	COG0800	Aldolase
HRQ91_09825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HRQ91_09830	COG2755	lipolytic protein G-D-S-L family
HRQ91_09835	COG0517	IMP dehydrogenase activity
HRQ91_09835	COG0516	GMP reductase activity
HRQ91_09840	COG1053	succinate dehydrogenase
HRQ91_09850	COG0587	DNA-directed DNA polymerase activity
HRQ91_09855	COG0762	integral membrane protein
HRQ91_09860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HRQ91_09865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HRQ91_09870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HRQ91_09880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HRQ91_09885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HRQ91_09890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HRQ91_09900	COG1773	rubredoxin
HRQ91_09905	COG2033	superoxide reductase activity
HRQ91_09910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HRQ91_09915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HRQ91_09935	COG0328	RNA-DNA hybrid ribonuclease activity
HRQ91_09940	COG0295	cytidine deaminase activity
HRQ91_09945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HRQ91_09980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HRQ91_09990	COG4166	transmembrane transport
HRQ91_10000	COG1028	Short-chain dehydrogenase reductase Sdr
HRQ91_10005	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HRQ91_10015	COG0693	protein deglycase activity
HRQ91_10020	COG4565	transcriptional regulatory protein
HRQ91_10025	COG5002	protein histidine kinase activity
HRQ91_10025	COG2205	protein histidine kinase activity
HRQ91_10025	COG0784	Response regulator, receiver
HRQ91_10035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRQ91_10040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HRQ91_10045	COG0484	heat shock protein binding
HRQ91_10050	COG1193	negative regulation of DNA recombination
HRQ91_10080	COG0714	Associated with various cellular activities
HRQ91_10120	COG1127	ABC transporter
HRQ91_10150	COG0357	Ribosomal RNA small subunit methyltransferase G
HRQ91_10160	COG0436	Aminotransferase
HRQ91_10165	COG1522	sequence-specific DNA binding
HRQ91_10170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HRQ91_10175	COG3858	chitin binding
HRQ91_10195	COG0012	GTP binding
HRQ91_10200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HRQ91_10205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HRQ91_10215	COG1051	belongs to the nudix hydrolase family
HRQ91_10230	COG0166	Belongs to the GPI family
HRQ91_10250	COG1477	protein flavinylation
HRQ91_10255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HRQ91_10265	COG1272	protein, Hemolysin III
HRQ91_10270	COG0730	response to heat
HRQ91_10275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HRQ91_10280	COG3012	SEC-C Motif Domain Protein
HRQ91_10285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HRQ91_10300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRQ91_10320	COG2721	sulfolactate sulfo-lyase activity
HRQ91_10325	COG0246	Mannitol dehydrogenase
HRQ91_10330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_10330	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_10340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_10345	COG1063	alcohol dehydrogenase
HRQ91_10380	COG0840	transmembrane signaling receptor activity
HRQ91_10390	COG1349	DNA-binding transcription factor activity
HRQ91_10400	COG1129	ABC transporter
HRQ91_10405	COG1172	Belongs to the binding-protein-dependent transport system permease family
HRQ91_10410	COG1069	ribulokinase activity
HRQ91_10430	COG1573	uracil-dna glycosylase
HRQ91_10465	COG0579	oxidoreductase
HRQ91_10515	COG0501	Belongs to the peptidase M48B family
HRQ91_10520	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
HRQ91_10525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_10545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_10555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_10570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HRQ91_10585	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HRQ91_10590	COG1309	transcriptional regulator
HRQ91_10595	COG0116	Belongs to the methyltransferase superfamily
HRQ91_10600	COG0167	dihydroorotate dehydrogenase activity
HRQ91_10605	COG0284	orotidine-5'-phosphate decarboxylase activity
HRQ91_10610	COG0318	PFAM AMP-dependent synthetase and ligase
HRQ91_10650	COG2207	Transcriptional regulator
HRQ91_10650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HRQ91_10655	COG4209	transmembrane transport
HRQ91_10660	COG0395	ABC-type sugar transport system, permease component
HRQ91_10665	COG1653	transport
HRQ91_10675	COG1968	undecaprenyl-diphosphatase activity
HRQ91_10680	COG1132	(ABC) transporter
HRQ91_10690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HRQ91_10690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HRQ91_10700	COG0151	Belongs to the GarS family
HRQ91_10710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HRQ91_10715	COG3250	beta-galactosidase activity
HRQ91_10720	COG0395	ABC-type sugar transport system, permease component
HRQ91_10725	COG1175	transmembrane transport
HRQ91_10730	COG1653	transport
HRQ91_10735	COG1609	Transcriptional regulator
HRQ91_10735	COG2207	Transcriptional regulator
HRQ91_10750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HRQ91_10755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HRQ91_10760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HRQ91_10775	COG0641	radical SAM
HRQ91_10780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HRQ91_10785	COG3507	Belongs to the glycosyl hydrolase 43 family
HRQ91_10815	COG2382	esterase
HRQ91_10820	COG1175	transmembrane transport
HRQ91_10825	COG0395	ABC-type sugar transport system, permease component
HRQ91_10840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HRQ91_10850	COG1121	(ABC) transporter
HRQ91_10855	COG0493	'glutamate synthase
HRQ91_10865	COG2183	response to ionizing radiation
HRQ91_10890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HRQ91_10920	COG3116	cell division
HRQ91_10920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HRQ91_10925	COG0084	hydrolase, TatD family'
HRQ91_10930	COG0739	heme binding
HRQ91_10945	COG1774	PSP1 C-terminal conserved region
HRQ91_10955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HRQ91_10985	COG0442	prolyl-tRNA aminoacylation
HRQ91_11005	COG1733	regulation of RNA biosynthetic process
HRQ91_11050	COG0281	malic enzyme
HRQ91_11065	COG0488	(ABC) transporter
HRQ91_11070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HRQ91_11090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HRQ91_11105	COG1312	Catalyzes the dehydration of D-mannonate
HRQ91_11140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HRQ91_11150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HRQ91_11150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HRQ91_11160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HRQ91_11165	COG4948	Mandelate Racemase Muconate Lactonizing
HRQ91_11170	COG2084	Dehydrogenase
HRQ91_11180	COG0546	phosphoglycolate phosphatase activity
HRQ91_11195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HRQ91_11320	COG0110	maltose O-acetyltransferase activity
HRQ91_11335	COG0656	L-ascorbic acid biosynthetic process
HRQ91_11345	COG1132	(ABC) transporter
HRQ91_11345	COG2375	cellular response to nickel ion
HRQ91_11350	COG1132	(ABC) transporter
HRQ91_11355	COG1132	(ABC) transporter
HRQ91_11375	COG0840	transmembrane signaling receptor activity
HRQ91_11420	COG1022	Amp-dependent synthetase and ligase
HRQ91_11430	COG3264	Mechanosensitive ion channel
HRQ91_11430	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HRQ91_11440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HRQ91_11450	COG1674	ftsk spoiiie
HRQ91_11455	COG0205	6-phosphofructokinase activity
HRQ91_11465	COG1609	Transcriptional regulator
HRQ91_11480	COG2972	Histidine kinase
HRQ91_11490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HRQ91_11510	COG0697	spore germination
HRQ91_11525	COG0765	amino acid transport
HRQ91_11540	COG0492	ferredoxin-NADP+ reductase activity
HRQ91_11545	COG2502	aspartate--ammonia ligase
HRQ91_11555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HRQ91_11560	COG1609	Transcriptional regulator
HRQ91_11620	COG4115	mRNA cleavage
HRQ91_11635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HRQ91_11655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HRQ91_11660	COG0326	Molecular chaperone. Has ATPase activity
HRQ91_11700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HRQ91_11705	COG0187	DNA topoisomerase II activity