locus-tag class description FUT82_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FUT82_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FUT82_00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FUT82_00020 ENOG4106C4Y Protein of unknown function (DUF721) FUT82_00035 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT82_00040 ENOG4105C8J )-transporter FUT82_00045 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT82_00050 ENOG4105EAD ABC transporter FUT82_00055 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FUT82_00060 ENOG4105F2I Transposase FUT82_00065 ENOG4105CDA abc transporter atp-binding protein FUT82_00075 ENOG4105CIZ coA-substrate-specific enzyme activase FUT82_00085 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FUT82_00095 ENOG4105CIN aminoacyl-histidine dipeptidase FUT82_00100 ENOG4108IUW ABC transporter FUT82_00120 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) FUT82_00130 ENOG4108ZVA radical SAM domain protein FUT82_00140 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) FUT82_00145 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FUT82_00150 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FUT82_00175 ENOG4105E98 transcriptional regulator DeoR family FUT82_00185 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT82_00190 ENOG4105CT4 transporter FUT82_00195 ENOG4105CNT hydrolase family 2 FUT82_00200 ENOG4105D2H Uronic isomerase FUT82_00205 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT82_00215 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT82_00220 ENOG4105DEI Mannitol dehydrogenase FUT82_00225 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FUT82_00235 ENOG4105II7 pyrroline-5-carboxylate reductase FUT82_00240 ENOG4105F4G Membrane FUT82_00255 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FUT82_00260 ENOG4105VVB FUT82_00265 ENOG4106KG8 FUT82_00270 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FUT82_00275 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) FUT82_00285 ENOG4108EKI Dehydrogenase FUT82_00305 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT82_00360 ENOG4105C3S Mate efflux family protein FUT82_00365 ENOG4105C75 arginyL-tRNA synthetase FUT82_00380 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_00385 ENOG4107RFY SbcCD D subunit FUT82_00390 ENOG4105EYH Exonuclease FUT82_00395 ENOG4105DQ6 Transposase FUT82_00405 ENOG4105DQ6 Transposase FUT82_00415 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_00630 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_00635 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FUT82_00640 ENOG4107QNG Phosphoribosylglycinamide synthetase FUT82_00645 ENOG4105DC1 bifunctional purine biosynthesis protein purh FUT82_00665 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FUT82_00670 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT82_00675 ENOG4108HM4 ABC transporter FUT82_00680 ENOG4105D38 putrescine abc transporter FUT82_00685 ENOG4105F38 ABC transporter, permease FUT82_00690 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_00920 ENOG4105E0M Sulfatase FUT82_00925 ENOG4105E0M Sulfatase FUT82_00945 ENOG4105DRR Transcriptional regulator, GntR family FUT82_00960 ENOG4105CV8 reductase FUT82_00965 ENOG4105DZW Dipeptidase FUT82_00975 ENOG4105CGH 5'-nucleotidase FUT82_01000 ENOG4105DAN ATP-dependent protease FUT82_01030 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FUT82_01035 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FUT82_01050 ENOG4105C3J Cysteine desulfurase FUT82_01055 ENOG4108DBC nitroreductase FUT82_01065 ENOG4105DQ6 Transposase FUT82_01075 ENOG4105D8D Type III FUT82_01080 ENOG4107QMH DNA methylase FUT82_01090 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT82_01095 ENOG4105C8J )-transporter FUT82_01100 ENOG4105CSM endonuclease III FUT82_01110 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FUT82_01115 ENOG4105ZAM anti-sigma-28 factor flgm family protein FUT82_01130 ENOG4107V9H nitrite transporter FUT82_01135 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FUT82_01155 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_01185 ENOG4105C37 (CBS) domain FUT82_01315 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT82_01485 ENOG4105DRR Transcriptional regulator, GntR family FUT82_01500 ENOG4105CV8 reductase FUT82_01515 ENOG4105CGH 5'-nucleotidase FUT82_01540 ENOG4105DAN ATP-dependent protease FUT82_01570 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FUT82_01575 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FUT82_01590 ENOG4105C3J Cysteine desulfurase FUT82_01595 ENOG4108DBC nitroreductase FUT82_01605 ENOG4105DQ6 Transposase FUT82_01615 ENOG4105D8D Type III FUT82_01620 ENOG4107QMH DNA methylase FUT82_01630 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT82_01635 ENOG4105C8J )-transporter FUT82_01640 ENOG4105CSM endonuclease III FUT82_01650 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FUT82_01655 ENOG4105ZAM anti-sigma-28 factor flgm family protein FUT82_01670 ENOG4107V9H nitrite transporter FUT82_01675 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FUT82_01695 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_01715 ENOG4108JU6 CBS domain protein FUT82_01720 ENOG4105C37 (CBS) domain FUT82_01825 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT82_01975 ENOG4105E0M Sulfatase FUT82_01980 ENOG4105E0M Sulfatase FUT82_02000 ENOG4105DRR Transcriptional regulator, GntR family FUT82_02015 ENOG4105CV8 reductase FUT82_02020 ENOG4105DZW Dipeptidase FUT82_02030 ENOG4105CGH 5'-nucleotidase FUT82_02055 ENOG4105DAN ATP-dependent protease FUT82_02085 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FUT82_02090 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FUT82_02105 ENOG4105C3J Cysteine desulfurase FUT82_02110 ENOG4108DBC nitroreductase FUT82_02120 ENOG4105DQ6 Transposase FUT82_02130 ENOG4105D8D Type III FUT82_02135 ENOG4107QMH DNA methylase FUT82_02145 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT82_02150 ENOG4105C8J )-transporter FUT82_02155 ENOG4105CSM endonuclease III FUT82_02165 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FUT82_02170 ENOG4105ZAM anti-sigma-28 factor flgm family protein FUT82_02185 ENOG4107V9H nitrite transporter FUT82_02190 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FUT82_02210 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_02230 ENOG4108JU6 CBS domain protein FUT82_02235 ENOG4105C37 (CBS) domain FUT82_02340 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT82_02460 ENOG4105CEC DNA methylase N-4 N-6 FUT82_02505 ENOG4105F2I Transposase FUT82_02545 ENOG4105M7P phage repressor FUT82_02765 ENOG4105D6S protein involved in catabolism of external DNA FUT82_02775 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FUT82_02785 ENOG4105C37 (CBS) domain FUT82_02800 ENOG4105CGH 5'-nucleotidase FUT82_02810 ENOG4105CB5 ATP-dependent DNA helicase recG FUT82_02815 ENOG4105C22 threonyL-tRNA synthetase FUT82_02825 ENOG41082MQ UPF0178 protein FUT82_02830 ENOG4105EIP mannose-6-phosphate isomerase FUT82_02835 ENOG4106BMT Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) FUT82_02840 ENOG4106BH8 FUT82_02845 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FUT82_02850 ENOG41084MZ 50S ribosomal protein L35 FUT82_02855 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FUT82_02860 ENOG4105C0H protease FUT82_02865 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT82_02880 ENOG41083NY Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FUT82_02885 ENOG4105E66 phosphoriboisomerase A FUT82_02890 ENOG4107YNV 3-dehydroquinate dehydratase FUT82_02905 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FUT82_02910 ENOG4105DQ6 Transposase FUT82_02925 ENOG4105F2I Transposase FUT82_02945 ENOG4105DRS transport system, permease FUT82_02955 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FUT82_02970 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FUT82_02975 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FUT82_02980 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FUT82_02985 ENOG4105DTN riboflavin biosynthesis protein ribF FUT82_02990 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FUT82_02995 ENOG41080JB Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FUT82_03005 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FUT82_03010 ENOG4105CHV Transcription elongation factor NusA FUT82_03015 ENOG410854D Required for maturation of 30S ribosomal subunits (By similarity) FUT82_03020 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FUT82_03040 ENOG4105F2I Transposase FUT82_03050 ENOG4105BZ1 (ABC) transporter FUT82_03055 ENOG4105BZ1 (ABC) transporter FUT82_03070 ENOG4108UHU Aldolase FUT82_03090 ENOG4105BZU Histidine kinase FUT82_03095 ENOG4105BZU Histidine kinase FUT82_03110 ENOG4108JE9 extracellular solute-binding protein family 1 FUT82_03120 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FUT82_03145 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FUT82_03155 ENOG4105DFU Cell wall formation (By similarity) FUT82_03165 ENOG4108Z4J Cytidine monophosphate kinase FUT82_03305 ENOG4105CGH 5'-nucleotidase FUT82_03310 ENOG4105EEI dihydropteroate synthase FUT82_03340 ENOG4105C7N Xanthine uracil vitamin C permease FUT82_03365 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT82_03385 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FUT82_03390 ENOG4105CMH dehydratase FUT82_03400 ENOG4105D6U Sodium Glutamate Symporter FUT82_03405 ENOG4107QX3 carboxylase FUT82_03410 ENOG4107UHT Glutaconate CoA-transferase FUT82_03415 ENOG4105DMN coenzyme A transferase FUT82_03420 ENOG4105D9Q decarboxylase (Beta subunit) FUT82_03425 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein FUT82_03435 ENOG4105D6U Sodium Glutamate Symporter FUT82_03440 ENOG4105C5I Dehydrogenase FUT82_03450 ENOG4105CQ7 ATP-dependent helicase FUT82_03460 ENOG41084P6 50S ribosomal protein l28 FUT82_03475 ENOG4108SSC basic membrane FUT82_03485 ENOG4108TWB ABC transporter (Permease FUT82_03490 ENOG4108ZV0 ABC transporter, permease FUT82_03500 ENOG41067MG lrgb family FUT82_03520 ENOG4107SFZ crispr-associated protein FUT82_03545 ENOG4105D2N Aldolase FUT82_03555 ENOG4108V2B Flagellar filament outer layer protein FUT82_03560 ENOG4105JTB FUT82_03565 ENOG4106FRC FUT82_03570 ENOG4108J59 Extracellular solute-binding protein, family 5 FUT82_03575 ENOG4105G9E FUT82_03585 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT82_03605 ENOG4107XHD Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT82_03610 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT82_03620 ENOG4108HU6 Metal dependent phosphohydrolase FUT82_03630 ENOG4105KRQ Addiction module toxin, Txe YoeB family FUT82_03640 ENOG4105C0D helicase FUT82_03650 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FUT82_03655 ENOG4107S6Z Na H antiporter FUT82_03670 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FUT82_03680 ENOG4108HW3 (ABC) transporter FUT82_03685 ENOG4105EAD ABC transporter FUT82_03690 ENOG4105CDA abc transporter atp-binding protein FUT82_03700 ENOG4106W1H FUT82_03705 ENOG4107R2U Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FUT82_03715 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT82_03725 ENOG4107RIZ hflk protein FUT82_03730 ENOG4105EPW hflc protein FUT82_03750 ENOG4105G6Z alkaline phosphatase FUT82_03775 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT82_03795 ENOG4107SJN Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FUT82_03800 ENOG4105K4W Could be involved in septation (By similarity) FUT82_03810 ENOG4107TVT This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FUT82_03815 ENOG4107THF Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FUT82_03820 ENOG41069X2 FUT82_03830 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FUT82_03855 ENOG4105CM4 permease protein FUT82_03860 ENOG4108IPW abc transporter atp-binding protein FUT82_03865 ENOG4107QKZ Ompa motb domain protein FUT82_03875 ENOG4105BZ1 (ABC) transporter FUT82_03890 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FUT82_03895 ENOG4105CY0 Metallo-Beta-Lactamase FUT82_03900 ENOG4105C2N RNA methyltransferase TrmH family group 3 FUT82_03915 ENOG4107GWN repeat protein FUT82_03920 ENOG4105BZU Histidine kinase FUT82_03925 ENOG4105BZU Histidine kinase FUT82_03935 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FUT82_03945 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FUT82_03950 ENOG4108KS2 transglutaminase domain protein FUT82_03965 ENOG4105C8N cysteinyl-tRNA synthetase FUT82_03970 ENOG4107QWW Cell wall formation (By similarity) FUT82_03975 ENOG4105IJJ transcriptional regulator, crp fnr family FUT82_03990 ENOG4105BZU Histidine kinase FUT82_03995 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FUT82_04005 ENOG4105DQ6 Transposase FUT82_04015 ENOG4105DQ6 Transposase FUT82_04025 ENOG4109031 FUT82_04030 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FUT82_04040 ENOG4105F2I Transposase FUT82_04050 ENOG410600T transposase FUT82_04100 ENOG4105CJ2 (LipO)protein FUT82_04120 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_04130 ENOG4105CTQ phosphohexokinase FUT82_04145 ENOG4107EFR Flavocytochrome c FUT82_04150 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_04160 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_04170 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT82_04175 ENOG4107QIV Cytochrome c biogenesis protein FUT82_04180 ENOG4106AHS FUT82_04185 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) FUT82_04190 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FUT82_04205 ENOG4105K95 (LipO)protein FUT82_04230 ENOG4108JQ1 Dehydrogenase FUT82_04240 ENOG4105C26 Dehydrogenase FUT82_04250 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) FUT82_04255 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT82_04275 ENOG4105CHJ isochorismatase hydrolase FUT82_04280 ENOG4106N3A copper homeostasis protein cutc FUT82_04290 ENOG4108JJ9 ABC, transporter FUT82_04295 ENOG4105BZ1 (ABC) transporter FUT82_04305 ENOG4108IUZ ABC transporter FUT82_04335 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FUT82_04345 ENOG4108PJD permease FUT82_04350 ENOG4106RHC FUT82_04375 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FUT82_04390 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FUT82_04395 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FUT82_04400 ENOG4105CUT histidyl-tRNA synthetase FUT82_04410 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FUT82_04415 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FUT82_04435 ENOG4105CJR Integral membrane protein (MviN FUT82_04440 ENOG4108Y51 tRNA-binding protein FUT82_04490 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FUT82_04515 ENOG4105C4M (Ubiquinol oxidase) subunit I FUT82_04520 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FUT82_04525 ENOG4108JJ9 ABC, transporter FUT82_04530 ENOG4108JJ8 (ABC) transporter FUT82_04535 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT82_04540 ENOG4105VEM Conserved domain protein FUT82_04550 ENOG4105CGK Exodeoxyribonuclease III FUT82_04555 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FUT82_04560 ENOG4105C5Y PTS System FUT82_04575 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FUT82_04580 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FUT82_04600 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FUT82_04605 ENOG4105WD1 Membrane FUT82_04610 ENOG4107QNB Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FUT82_04620 ENOG4107U1W v-type ATP synthase subunit I FUT82_04625 ENOG4108WBK V-type ATP synthase subunit D FUT82_04630 ENOG4107RQX Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit FUT82_04635 ENOG4107RVI Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) FUT82_04645 ENOG4108RY1 ATP synthase, subunit E FUT82_04930 ENOG4105Z8H single-stranded DNA-binding protein FUT82_04955 ENOG4108PNI recT protein FUT82_04975 ENOG4108NF7 phage-type endonuclease FUT82_05005 ENOG41067S9 phage shock protein C, PspC FUT82_05115 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT82_05260 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FUT82_05265 ENOG4106N2C FUT82_05275 ENOG4107R2W ABC transporter, permease FUT82_05280 ENOG4105C2J ABC transporter FUT82_05285 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT82_05305 ENOG4108NF7 phage-type endonuclease FUT82_05325 ENOG4108PNI recT protein FUT82_05355 ENOG4105Z8H single-stranded DNA-binding protein FUT82_05405 ENOG4105C5X domain protein FUT82_05415 ENOG41062BZ domain protein FUT82_05425 ENOG4107QW4 alcohol dehydrogenase FUT82_05435 ENOG4105K4H Nlp p60 protein FUT82_05440 ENOG4105CEY Amp-dependent synthetase and ligase FUT82_05445 ENOG41083CW dedA protein FUT82_05450 ENOG4107QMG Nad synthetase FUT82_05460 ENOG410684W FUT82_05465 ENOG4105KG3 cytidine deaminase FUT82_05470 ENOG4105C1A potassium transporter peripheral membrane FUT82_05475 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FUT82_05495 ENOG4108UT2 hemolysin iii FUT82_05515 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_05520 ENOG4108JA2 transcriptioN-repair coupling factor FUT82_05530 ENOG4105CJW magnesium transporter FUT82_05535 ENOG4105D6E homoserine dehydrogenase FUT82_05540 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FUT82_05545 ENOG4105CVG Homoserine O-transsuccinylase FUT82_05555 ENOG4105DR4 Methyltransferase FUT82_05560 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FUT82_05570 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FUT82_05575 ENOG4108JQ7 (ABC) transporter FUT82_05590 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT82_05600 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT82_05605 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FUT82_05620 ENOG4105CKI cobalamin synthesis protein FUT82_05630 ENOG4105E98 transcriptional regulator DeoR family FUT82_05640 ENOG4105D7K pfkb domain protein FUT82_05645 ENOG4105D2N Aldolase FUT82_05650 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT82_05655 ENOG4105CI2 imidazolone-5-propionate hydrolase FUT82_05690 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FUT82_05700 ENOG4105C1J atp-dependent rna helicase FUT82_05720 ENOG4105CJ1 ABC, transporter FUT82_05730 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT82_05735 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FUT82_05740 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FUT82_05745 ENOG4105C2J ABC transporter FUT82_05750 ENOG4105CNN ABC, transporter FUT82_05765 ENOG4105C28 cystathionine FUT82_05775 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component FUT82_05785 ENOG4105F2I Transposase FUT82_05795 ENOG4105CUY Mechanosensitive ion channel FUT82_05800 ENOG4105DJ0 Poly(A) Polymerase FUT82_05830 ENOG4105D7A ATP-binding protein FUT82_05840 ENOG4105DQ6 Transposase FUT82_05875 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_05885 ENOG4108RCM Nitroreductase FUT82_05895 ENOG41073FS FUT82_05905 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT82_05910 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT82_05920 ENOG4107TFB basic membrane FUT82_05925 ENOG4108JQ9 ABC transporter FUT82_05930 ENOG4105UIB (ABC) transporter FUT82_05940 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT82_05990 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FUT82_06005 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FUT82_06010 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FUT82_06015 ENOG4107EFR Flavocytochrome c FUT82_06020 ENOG4105CBX hi0933 family FUT82_06025 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT82_06120 ENOG4105KT7 mgtC SapB transporter FUT82_06125 ENOG4106ARS FUT82_06140 ENOG4107R21 site-determining protein FUT82_06150 ENOG4107WGG Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FUT82_06155 ENOG4105DF5 DNA topoisomerase IV, subunit A FUT82_06170 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FUT82_06175 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT82_06180 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FUT82_06215 ENOG4105BZU Histidine kinase FUT82_06225 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FUT82_06230 ENOG4105F8V Hydrolase, tatD family FUT82_06235 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT82_06240 ENOG4105WJX transcriptional regulator MERR family FUT82_06250 ENOG4106QD2 FUT82_06255 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FUT82_06260 ENOG4105C3F Signal peptidase i FUT82_06265 ENOG4105CSA Coproporphyrinogen iii oxidase FUT82_06270 ENOG4106YRG FUT82_06275 ENOG41084AY Binds together with S18 to 16S ribosomal RNA (By similarity) FUT82_06280 ENOG4105Z8H single-stranded DNA-binding protein FUT82_06285 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FUT82_06290 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FUT82_06295 ENOG4105CDU Replicative dna helicase FUT82_06335 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT82_06340 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT82_06375 ENOG4105DM4 PTS System FUT82_06380 ENOG41077G2 FUT82_06390 ENOG4105MPN Membrane FUT82_06400 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FUT82_06405 ENOG4105CFG Acts as a chaperone (By similarity) FUT82_06410 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FUT82_06415 ENOG4108JIP Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity) FUT82_06440 ENOG4107WUB V-type ATPase 116 kDa subunit FUT82_06455 ENOG4105DM4 PTS System FUT82_06460 ENOG4106447 Preprotein translocase subunit SecG FUT82_06475 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FUT82_06480 ENOG4105DD7 kinase (PfkB family FUT82_06485 ENOG4107YM1 mraZ protein FUT82_06490 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FUT82_06500 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FUT82_06505 ENOG4105CNI cell division protein FtsW FUT82_06510 ENOG410812A polypeptide-transport-associated domain protein, FtsQ-type FUT82_06515 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FUT82_06520 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FUT82_06525 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT82_06535 ENOG4105C79 DNA protecting protein DprA FUT82_06540 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FUT82_06545 ENOG4108I7H Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT82_06550 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FUT82_06555 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FUT82_06565 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FUT82_06570 ENOG4108ZC9 flagellar basal-body rod protein flgc FUT82_06575 ENOG41069WH flagellar hook-basal body complex FUT82_06580 ENOG4107U2N Flagellar M-ring protein FUT82_06585 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT82_06590 ENOG4105W2B Flagellar assembly protein FUT82_06595 ENOG4108JIR Flagellum-specific ATP synthase FUT82_06610 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FUT82_06625 ENOG4105Q84 sucrose synthase FUT82_06650 ENOG4105C6F GntR Family Transcriptional Regulator FUT82_06685 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FUT82_06690 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FUT82_06695 ENOG41090QR FUT82_06710 ENOG4105CH2 amidohydrolase FUT82_06725 ENOG4105CSA Coproporphyrinogen iii oxidase FUT82_06735 ENOG4108V1T peptidylprolyl cis-trans isomerase FUT82_06760 ENOG4108RVA ribokinase FUT82_06765 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FUT82_06770 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FUT82_06785 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_06825 ENOG4105DQ6 Transposase FUT82_06830 ENOG4105CTQ phosphohexokinase FUT82_06835 ENOG4105HCZ FUT82_06850 ENOG4105EAH synthase FUT82_06860 ENOG4105D48 metallophosphoesterase FUT82_06885 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FUT82_06890 ENOG4107JR8 Colicin v production protein FUT82_06895 ENOG4107QRG dna polymerase iii FUT82_06900 ENOG4105BZU Histidine kinase FUT82_06905 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT82_06955 ENOG4105CE1 Ferrous iron transport protein b FUT82_06975 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT82_06980 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FUT82_06985 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FUT82_06990 ENOG41084YP 30S ribosomal protein S21 FUT82_07000 ENOG4108346 Beta-lactamase domain protein FUT82_07010 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FUT82_07015 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FUT82_07020 ENOG4105C98 muts2 protein FUT82_07035 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FUT82_07040 ENOG4105CGA flagellar basal-body rod protein FlgG FUT82_07045 ENOG410680E Flagellar protein FUT82_07050 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FUT82_07060 ENOG4108YZY peptidylprolyl cis-trans isomerase FUT82_07070 ENOG4108M1M outer membrane lipoprotein-sorting protein FUT82_07080 ENOG4108RZE Tetr family transcriptional regulator FUT82_07090 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) FUT82_07095 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT82_07100 ENOG4105D48 metallophosphoesterase FUT82_07120 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FUT82_07145 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FUT82_07155 ENOG4105DUA (citrate (pro-3S)-lyase ligase FUT82_07165 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT82_07175 ENOG41081IW Inherit from COG: Membrane FUT82_07185 ENOG4105FEU K -dependent Na -Ca exchanger FUT82_07200 ENOG4105EAM Na Pi-cotransporter FUT82_07205 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FUT82_07220 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FUT82_07225 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT82_07230 ENOG4105W0I repeat-containing protein FUT82_07240 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FUT82_07250 ENOG4106TCE FUT82_07255 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FUT82_07280 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FUT82_07295 ENOG4105N98 Capsule biosynthesis protein capB FUT82_07300 ENOG4105C0B DNA polymerase III (alpha subunit) FUT82_07305 ENOG41067XK integral membrane protein FUT82_07310 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FUT82_07315 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FUT82_07330 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FUT82_07335 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT82_07345 ENOG4106SWD FUT82_07355 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FUT82_07365 ENOG4105E2D ec 3.2.1.52 FUT82_07370 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FUT82_07390 ENOG4105CFP Peptidase U32 FUT82_07415 ENOG4107W7Y Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FUT82_07425 ENOG41090Q2 FUT82_07460 ENOG4105WN5 stage II sporulation protein FUT82_07470 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FUT82_07480 ENOG4105K46 50S ribosomal protein l27 FUT82_07485 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FUT82_07490 ENOG4107X4V Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FUT82_07535 ENOG4105C19 ABC transporter FUT82_07540 ENOG4107SJW iron permease, FTR1 FUT82_07545 ENOG4108SDV Periplasmic Protein FUT82_07560 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT82_07575 ENOG4105C19 ABC transporter FUT82_07595 ENOG4105I7V membrAne FUT82_07600 ENOG4105EA8 2-Nitropropane dioxygenase FUT82_07605 ENOG4105ESV Glycosyl transferase, family 4 FUT82_07625 ENOG4105DR5 peptidase FUT82_07635 ENOG4108JQC penicillin-binding protein 1A FUT82_07645 ENOG41082BE ankyrin repeat-containing protein FUT82_07650 ENOG4105Z8J FUT82_07665 ENOG4106AG2 FUT82_07675 ENOG41068FD FUT82_07680 ENOG4105CU9 asparagine synthetase A FUT82_07685 ENOG4108V0P LemA family FUT82_07695 ENOG4105HA9 of methanol dehydrogenase type FUT82_07710 ENOG41061XC FUT82_07725 ENOG4107R3E Citrate transporter FUT82_07730 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FUT82_07745 ENOG4105CGA flagellar basal-body rod protein FlgG FUT82_07750 ENOG4108S3Y transcriptional regulator FUT82_07755 ENOG4105C5Y PTS System FUT82_07760 ENOG4108HCJ Hydrolase FUT82_07765 ENOG4105CS2 ec 3.2.1.21 FUT82_07770 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FUT82_07775 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT82_07790 ENOG4107XH4 PPIases accelerate the folding of proteins (By similarity) FUT82_07805 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FUT82_07820 ENOG4105VG0 50S ribosomal protein l34 FUT82_07830 ENOG4107S1W 4-alpha-glucanotransferase FUT82_07835 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FUT82_07845 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FUT82_07850 ENOG4105KZ7 phosphocarrier protein hpr FUT82_07865 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FUT82_07895 ENOG4105M7P phage repressor FUT82_07960 ENOG4105Z8H single-stranded DNA-binding protein FUT82_08205 ENOG4105W5Q DNA repair protein (RadC FUT82_08265 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FUT82_08280 ENOG4105C5S asparaginyl-tRNA synthetase FUT82_08285 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_08300 ENOG4107QSA Oxaloacetate decarboxylase FUT82_08305 ENOG4105D9Q decarboxylase (Beta subunit) FUT82_08310 ENOG4105EAB amino acid AbC transporter FUT82_08315 ENOG4108HW3 (ABC) transporter FUT82_08320 ENOG4108120 Pasta domain protein FUT82_08330 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FUT82_08335 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FUT82_08340 ENOG4106BN6 FUT82_08345 ENOG4108JDX DNA polymerase iii, epsilon subunit FUT82_08360 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase FUT82_08365 ENOG4106GZE FUT82_08380 ENOG4105F2I Transposase FUT82_08430 ENOG4105CVR type I restriction-modification system FUT82_08445 ENOG4105II7 pyrroline-5-carboxylate reductase FUT82_08460 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FUT82_08465 ENOG4106XJW FUT82_08480 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT82_08490 ENOG4108QUE repeat-containing protein FUT82_08495 ENOG4105FA0 parb-like partition protein FUT82_08500 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FUT82_08505 ENOG4105KME endoribonuclease L-psp FUT82_08515 ENOG4105C1B dTDP-glucose 4-6-dehydratase FUT82_08535 ENOG4105DMT epimerase dehydratase FUT82_08545 ENOG4107QQG Dehydrogenase FUT82_08550 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FUT82_08580 ENOG4105PSV Polysaccharide Biosynthesis Protein FUT82_08585 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT82_08595 ENOG4105J5G Transferase hexapeptide repeat containing protein FUT82_08630 ENOG4105EE0 oxidoreductase FUT82_08635 ENOG4107STF Involved in phosphonate degradation (By similarity) FUT82_08640 ENOG4105DTI Phosphonopyruvate decarboxylase FUT82_08675 ENOG4105C22 threonyL-tRNA synthetase FUT82_08705 ENOG4107RBJ symporter FUT82_08715 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_08745 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT82_08755 ENOG4105MJ2 Competence protein FUT82_08770 ENOG4105E9H Lytic Murein transglycosylase FUT82_08785 ENOG4105DR5 peptidase FUT82_08790 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FUT82_08795 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FUT82_08800 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FUT82_08825 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT82_08860 ENOG4105Z8H single-stranded DNA-binding protein FUT82_08890 ENOG4108PNI recT protein FUT82_08910 ENOG4108NF7 phage-type endonuclease FUT82_08925 ENOG4105BZ1 (ABC) transporter FUT82_08930 ENOG4105BZ1 (ABC) transporter FUT82_08935 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FUT82_08955 ENOG41062VP FUT82_08975 ENOG4105BZ1 (ABC) transporter FUT82_08980 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FUT82_08985 ENOG41071ED FUT82_09000 ENOG4106UUF FUT82_09015 ENOG4105SXG FUT82_09020 ENOG4105ZF0 Lipoprotein FUT82_09025 ENOG4105C26 Dehydrogenase FUT82_09030 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT82_09035 ENOG4105CNN ABC, transporter FUT82_09040 ENOG4105C2J ABC transporter FUT82_09045 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FUT82_09195 ENOG4105F2I Transposase FUT82_09315 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FUT82_09325 ENOG4105CJN penicillin-binding protein FUT82_09345 ENOG4107MD5 glycoside hydrolase, family FUT82_09350 ENOG41063XV FUT82_09355 ENOG4108ESY Metal dependent phosphohydrolase FUT82_09360 ENOG4105EJQ L-serine dehydratase FUT82_09370 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FUT82_09395 ENOG4108RAC Rubrerythrin FUT82_09405 ENOG4106SUR Protein of unknown function DUF115 FUT82_09415 ENOG4105DSE periplasmic solute binding protein FUT82_09420 ENOG4105FDK ABC transporter FUT82_09425 ENOG4105FAV ABC, transporter FUT82_09430 ENOG4105CH2 amidohydrolase FUT82_09450 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FUT82_09470 ENOG4105MUZ Protein of unknown function DUF2620 FUT82_09475 ENOG4106M0N transport system permease protein FUT82_09490 ENOG4106PKC pyridoxal phosphate binding FUT82_09495 ENOG4108626 Racemase FUT82_09500 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FUT82_09525 ENOG4106MPK FUT82_09530 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FUT82_09545 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT82_09560 ENOG41066A3 ATP guanido phosphotransferase FUT82_09585 ENOG4105C25 Primosomal protein n' FUT82_09590 ENOG4108UN4 phage SPO1 DNA polymerase-related protein FUT82_09600 ENOG4105C5H ABC transporter FUT82_09600 ENOG4105C5H ABC transporter FUT82_09610 ENOG41089XN FUT82_09625 ENOG4105EI2 Pseudouridine synthase FUT82_09645 ENOG4106SAP FUT82_09650 ENOG4107VE5 flagellar hook-associated protein FUT82_09660 ENOG4105I03 Flagellin FUT82_09665 ENOG4105I03 Flagellin FUT82_09675 ENOG4105C0P Mg chelatase subunit ChlI FUT82_09690 ENOG41071ZZ FUT82_09710 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FUT82_09715 ENOG4105K8N protein family UPF0079, ATPase FUT82_09725 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT82_09745 ENOG4105D98 threonine synthase FUT82_09760 ENOG4105CTZ aminopeptidase c FUT82_09770 ENOG4108UW5 maltose o-acetyltransferase FUT82_09775 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FUT82_09780 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FUT82_09800 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FUT82_09810 ENOG4105ZFX FUT82_09825 ENOG4108TSD Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT82_09840 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT82_09845 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FUT82_09850 ENOG4108MIC Mg-protoporphyrin IX methyl transferase FUT82_09855 ENOG4105BZW Glycerate kinase FUT82_09860 ENOG4105C6Z Gluconate FUT82_09880 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) FUT82_09890 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FUT82_09935 ENOG4105BZ1 (ABC) transporter FUT82_09940 ENOG4105BZ1 (ABC) transporter FUT82_09945 ENOG4105EHG Permease protein FUT82_09950 ENOG4105E0A ABC, transporter FUT82_09955 ENOG4105F2I Transposase FUT82_09990 ENOG4105DXX methyltransferase FUT82_10060 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT82_10085 ENOG4108JJB ABC transporter FUT82_10105 ENOG4107QMH DNA methylase FUT82_10125 ENOG4105CHY citrate lyase, alpha FUT82_10135 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) FUT82_10170 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT82_10175 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT82_10205 ENOG4105CVA phosphate FUT82_10215 ENOG4105E2Z phosphate ABC transporter (Permease FUT82_10220 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FUT82_10225 ENOG4108UTW Plays a role in the regulation of phosphate uptake FUT82_10230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FUT82_10235 ENOG4105BZU Histidine kinase FUT82_10240 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_10245 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FUT82_10255 ENOG41083MR nifu domain-containing protein FUT82_10275 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_10280 ENOG4105MQ3 flagellar protein FliS FUT82_10285 ENOG4106VWR FUT82_10290 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FUT82_10295 ENOG4106B9X FUT82_10300 ENOG4105DR9 pseudouridine synthase FUT82_10305 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FUT82_10310 ENOG4105BZU Histidine kinase FUT82_10330 ENOG4105WH1 Two component transcriptional regulator luxr family FUT82_10345 ENOG4105BZ8 glutamate synthase FUT82_10350 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein FUT82_10355 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT82_10370 ENOG4105E5D amino acid FUT82_10410 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FUT82_10415 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FUT82_10460 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FUT82_10470 ENOG41085YX 50S ribosomal protein L32 FUT82_10475 ENOG41084E5 Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FUT82_10480 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FUT82_10485 ENOG4105F2I Transposase FUT82_10490 ENOG4105F0S class B acid phosphatase FUT82_10500 ENOG4105FE9 pseudouridine synthase FUT82_10505 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FUT82_10510 ENOG4105MBR gumn family FUT82_10515 ENOG4105C31 Tryptophanyl-tRNA synthetase FUT82_10525 ENOG4105CZV ABC transporter FUT82_10535 ENOG4107QJD pyruvate phosphate dikinase FUT82_10540 ENOG4108SXE FUT82_10545 ENOG41073RW Cytoplasmic filament protein A FUT82_10550 ENOG4105YQK von Willebrand factor type A domain FUT82_10565 ENOG4105DK7 lysyl-tRNA synthetase FUT82_10580 ENOG4106C6A Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FUT82_10585 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT82_10590 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT82_10595 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FUT82_10600 ENOG4108VZM 50s ribosomal protein L10 FUT82_10605 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) FUT82_10610 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FUT82_10615 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FUT82_10630 ENOG41084ED 50S ribosomal protein L33 FUT82_10640 ENOG4108Z29 Flavodoxin FUT82_10650 ENOG4105F2I Transposase FUT82_10660 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FUT82_10665 ENOG4105C2J ABC transporter FUT82_10670 ENOG4105CNN ABC, transporter FUT82_10675 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FUT82_10710 ENOG4105C0H protease FUT82_10715 ENOG4105CE4 GlcNAc 6-P deacetylase FUT82_10725 ENOG4108IXY short-chain dehydrogenase reductase FUT82_10735 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FUT82_10745 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FUT82_10760 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT82_10765 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FUT82_10770 ENOG4105W87 Cbs domain FUT82_10775 ENOG4108IV0 ABC, transporter FUT82_10780 ENOG4105C0Z ABC transporter FUT82_10785 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FUT82_10790 ENOG4105C32 Amino acid ABC transporter (Permease) FUT82_10800 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT82_10805 ENOG41068UM RNA Polymerase FUT82_10815 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_10825 ENOG4106U5D Septum formation initiator FUT82_10830 ENOG410698I FUT82_10840 ENOG4105X4X Protein of unknown function DUF115 FUT82_10845 ENOG41090QV Protein of unknown function DUF115 FUT82_10880 ENOG4105DJV ribulose-phosphate 3-epimerase FUT82_10885 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) FUT82_10895 ENOG4105E2D ec 3.2.1.52 FUT82_10900 ENOG4105DZ1 carboxypeptidase FUT82_10910 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT82_11045 ENOG4105F2I Transposase FUT82_11150 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT82_11155 ENOG4105DRS transport system, permease FUT82_11160 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT82_11190 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT82_11195 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FUT82_11205 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FUT82_11220 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FUT82_11230 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FUT82_11240 ENOG410805Y Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FUT82_11250 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FUT82_11255 ENOG4107QJQ Mate efflux family protein FUT82_11260 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT82_11265 ENOG410691R Modulates RecA activity (By similarity) FUT82_11270 ENOG4108UJD 30S ribosomal protein S9 FUT82_11275 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FUT82_11285 ENOG4108JQ7 (ABC) transporter FUT82_11295 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT82_11300 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT82_11305 ENOG4107QSI ABC, transporter FUT82_11310 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT82_11315 ENOG410841Q phosphoesterase PA-phosphatase related protein FUT82_11330 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FUT82_11335 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FUT82_11340 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT82_11345 ENOG4105YFD chemotaxis, protein FUT82_11360 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_11380 ENOG4105EMN RNA polymerase sigma factor FUT82_11395 ENOG4105EHZ conserved protein UCP016719 FUT82_11405 ENOG4105CZN Potassium uptake protein FUT82_11410 ENOG4107ZYR domain protein FUT82_11425 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT82_11440 ENOG4105WN5 stage II sporulation protein FUT82_11460 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FUT82_11465 ENOG4105BZ1 (ABC) transporter FUT82_11470 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FUT82_11475 ENOG4105C7B Threonine dehydratase FUT82_11480 ENOG4105C28 cystathionine FUT82_11490 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT82_11500 ENOG4105F2I Transposase FUT82_11510 ENOG4105C94 Transporter FUT82_11520 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT82_11530 ENOG4105CKB glycosidase FUT82_11550 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FUT82_11560 ENOG4105CEM UPF0597 protein FUT82_11570 ENOG4108KP7 hydrolase FUT82_11575 ENOG4105T73 FUT82_11580 ENOG4105C8J )-transporter FUT82_11585 ENOG4105C4R Atp-dependent dna helicase FUT82_11590 ENOG4105TQV FUT82_11620 ENOG41082I4 UPF0102 protein FUT82_11625 ENOG4105CPI Metal Dependent Phosphohydrolase FUT82_11630 ENOG4105D00 flagellar biosynthetic protein flhB FUT82_11640 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FUT82_11645 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FUT82_11650 ENOG4107GQ3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FUT82_11655 ENOG4105VB6 UPF0109 protein FUT82_11660 ENOG4105K5M 30s ribosomal protein S16 FUT82_11695 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FUT82_11715 ENOG4107GGS FUT82_11720 ENOG4107R05 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT82_11725 ENOG41080VC Galactokinase (EC 2.7.1.6) FUT82_11730 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FUT82_11745 ENOG4106R77 FUT82_11755 ENOG4105DR5 peptidase FUT82_11760 ENOG4105DR5 peptidase FUT82_11765 ENOG4105BZ1 (ABC) transporter FUT82_11770 ENOG4105DWF phosphomethylpyrimidine kinase FUT82_11775 ENOG4105C8T Leucyl-tRNA synthetase FUT82_11795 ENOG4106JH4 FUT82_11800 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FUT82_11805 ENOG4105DN3 alpha-2-macroglobulin domain protein FUT82_11810 ENOG4108JQB penicillin-binding protein 1C FUT82_11815 ENOG4107QJE Chromosome Partitioning Protein FUT82_11820 ENOG4105FA0 parb-like partition protein FUT82_11830 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FUT82_12160 ENOG4105M7P phage repressor FUT82_12175 ENOG4105C1J atp-dependent rna helicase FUT82_12180 ENOG4107RBB ABC transporter, permease FUT82_12185 ENOG4107RBB ABC transporter, permease FUT82_12190 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT82_12210 ENOG4105CE9 30S ribosomal protein S2 FUT82_12215 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FUT82_12220 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FUT82_12225 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FUT82_12230 ENOG4105KNE Phosphatidate cytidylyltransferase FUT82_12235 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FUT82_12240 ENOG4105DZP Membrane-associated zinc metalloprotease FUT82_12245 ENOG41062Z1 FUT82_12250 ENOG4105X1A FUT82_12265 ENOG4105C3F Signal peptidase i FUT82_12270 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FUT82_12275 ENOG4105D07 Signal peptide peptidase, SppA FUT82_12300 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FUT82_12315 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT82_12320 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT82_12395 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_12430 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FUT82_12440 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FUT82_12460 ENOG4105DIH basic membrane FUT82_12465 ENOG4108JQ9 ABC transporter FUT82_12470 ENOG4105UIB (ABC) transporter FUT82_12505 ENOG4105E4P ATPase (AAA FUT82_12545 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT82_12600 ENOG4105C5H ABC transporter FUT82_12605 ENOG4105I76 (LipO)protein FUT82_12610 ENOG4105F2I Transposase FUT82_12625 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FUT82_12635 ENOG4107RJF diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) FUT82_12640 ENOG41082Y9 Single-strand binding protein FUT82_12655 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT82_12665 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FUT82_12670 ENOG4108R6K riboflavin synthase, subunit alpha FUT82_12680 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FUT82_12685 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FUT82_12700 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FUT82_12720 ENOG4105DRS transport system, permease FUT82_12735 ENOG4105CA9 Pyruvate kinase FUT82_12750 ENOG41082DI 50s ribosomal protein l31 FUT82_12755 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FUT82_12760 ENOG4105CEV competence damage-inducible protein FUT82_12770 ENOG4107RI4 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT82_12780 ENOG41083IJ DNA-binding protein FUT82_12785 ENOG41086BH Binds directly to 16S ribosomal RNA (By similarity) FUT82_12795 ENOG4107NGC Flagellar filament outer layer protein FUT82_12805 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FUT82_12825 ENOG4105IJJ transcriptional regulator, crp fnr family FUT82_12830 ENOG4105K63 Thioredoxin FUT82_12835 ENOG41081GK CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase FUT82_12840 ENOG4105F8V Hydrolase, tatD family FUT82_12850 ENOG4105K6T rare lipoprotein A FUT82_12870 ENOG41090KZ FUT82_12890 ENOG4106UV5 membrane protein A FUT82_12900 ENOG4105CFP Peptidase U32 FUT82_12910 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FUT82_12915 ENOG4107Z25 Basic membrane protein FUT82_12920 ENOG4105M7K Involved in the transcription termination process (By similarity) FUT82_12940 ENOG4105BZA Phosphoglycerate kinase FUT82_12945 ENOG4105CP7 Triose-phosphate isomerase FUT82_12955 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) FUT82_12960 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FUT82_12985 ENOG4105VUF Transcriptional regulator FUT82_13015 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FUT82_13020 ENOG4105D6U Sodium Glutamate Symporter FUT82_13040 ENOG4105WH1 Two component transcriptional regulator luxr family FUT82_13045 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT82_13065 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT82_13075 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT82_13105 ENOG4107W93 Dihydroorotate dehydrogenase FUT82_13110 ENOG4107XPQ Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FUT82_13120 ENOG4105DVT helicase FUT82_13125 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FUT82_13130 ENOG4105DC7 peptidase M24 FUT82_13140 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT82_13145 ENOG4105G3C Type iv pilus assembly FUT82_13175 ENOG4105DVC DnaJ domain protein FUT82_13180 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FUT82_13185 ENOG4105CV1 Transketolase (EC 2.2.1.1) FUT82_13200 ENOG4106TP1 FUT82_13215 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FUT82_13225 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT82_13230 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit FUT82_13235 ENOG4105DGN Electron transport complex FUT82_13240 ENOG4105DZB Electron transport complex FUT82_13250 ENOG4105D6A Electron transport complex FUT82_13255 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) FUT82_13275 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT82_13285 ENOG4105HHA aminodeoxychorismate lyase FUT82_13290 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FUT82_13295 ENOG4107QVY Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT82_13315 ENOG4105DFF Rod shape-determining protein mreb FUT82_13330 ENOG4105CJN penicillin-binding protein FUT82_13335 ENOG4105CNI cell division protein FtsW FUT82_13340 ENOG4105EIB trna rrna methyltransferase FUT82_13350 ENOG4105C3J Cysteine desulfurase FUT82_13365 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FUT82_13370 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT82_13375 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FUT82_13380 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_13385 ENOG4105E0C molybdate abc transporter FUT82_13390 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FUT82_13400 ENOG4108RIR Molybdenum cofactor biosynthesis protein FUT82_13415 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FUT82_13420 ENOG4105CEV competence damage-inducible protein FUT82_13425 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT82_13430 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FUT82_13440 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FUT82_13445 ENOG4105BZ8 glutamate synthase FUT82_13450 ENOG4107RCH Diaminopropionate ammonia-lyase FUT82_13455 ENOG4107S4Y M20 DapE family protein YgeY FUT82_13460 ENOG4105IW6 Carbamoyltransferase FUT82_13480 ENOG410908R Methenyltetrahydrofolate cyclohydrolase FUT82_13485 ENOG4105CKU formyltetrahydrofolate synthetase FUT82_13490 ENOG4105CCS Glutamate formiminotransferase FUT82_13495 ENOG4105C84 Histidine ammonia-lyase FUT82_13500 ENOG4105D3Y Na H antiporter FUT82_13510 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FUT82_13515 ENOG4105EEI dihydropteroate synthase FUT82_13520 ENOG4105C8B TIGR00159 family FUT82_13530 ENOG41083V3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FUT82_13535 ENOG4108CER Uncharacterized protein conserved in bacteria (DUF2225) FUT82_13540 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FUT82_13545 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT82_13555 ENOG4105CYC Transferase FUT82_13560 ENOG4105E39 Enoyl-CoA hydratase FUT82_13565 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FUT82_13570 ENOG4105CNW domain protein FUT82_13575 ENOG4105C1G acyl-Coa dehydrogenase FUT82_13580 ENOG4105CHU acetyl-coa acetyltransferase FUT82_13595 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FUT82_13600 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FUT82_13605 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FUT82_13610 ENOG4108IQE Amp-dependent synthetase and ligase FUT82_13620 ENOG4107R5H iron (metal) dependent repressor, dtxr family FUT82_13625 ENOG4107RBD ABC, transporter FUT82_13630 ENOG4107RPQ ABC transporter FUT82_13635 ENOG4105DIK (ABC) transporter FUT82_13640 ENOG4107SIG periplasmic solute binding protein FUT82_13645 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT82_13655 ENOG4107V28 uracil phosphoribosyltransferase FUT82_13725 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT82_13770 ENOG4106TEA FUT82_13805 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FUT82_13810 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FUT82_13825 ENOG4105DFM M18 family aminopeptidase FUT82_13835 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FUT82_13840 ENOG4107I03 FUT82_13865 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FUT82_13875 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_13895 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FUT82_13905 ENOG4108UQV Membrane FUT82_13920 ENOG4105CAH Chromate FUT82_13940 ENOG4106S0F FUT82_13945 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FUT82_13950 ENOG4106GEY FUT82_13960 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FUT82_13970 ENOG4107Z9R response regulator FUT82_13980 ENOG4105YFD chemotaxis, protein FUT82_13985 ENOG4105CBS Chea signal transduction histidine kinase FUT82_14015 ENOG4105F1A Pyruvate formate-lyase FUT82_14020 ENOG4105C6N Formate acetyltransferase FUT82_14030 ENOG4105I03 Flagellin FUT82_14075 ENOG4105DFD Na H antiporter FUT82_14080 ENOG41083HS Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FUT82_14110 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_14130 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_14140 ENOG4105C3G gtp-binding protein FUT82_14150 ENOG4105VKD bioY protein FUT82_14155 ENOG4108JJB ABC transporter FUT82_14175 ENOG4108HHA Transketolase FUT82_14180 ENOG4108IUS Transketolase FUT82_14185 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FUT82_14210 ENOG4105DQ6 Transposase FUT82_14225 ENOG4105D7X high-affinity nickel-transporter FUT82_14260 ENOG4105CPF Cell wall formation (By similarity) FUT82_14270 ENOG4105BZ1 (ABC) transporter FUT82_14275 ENOG4105BZ1 (ABC) transporter FUT82_14280 ENOG4105BZ1 (ABC) transporter FUT82_14285 ENOG4105BZ1 (ABC) transporter FUT82_14290 ENOG4108JQ7 (ABC) transporter FUT82_14300 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT82_14320 ENOG4105C3M thioredoxin reductase FUT82_14325 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT82_14345 ENOG4105D3R alkyl hydroperoxide reductase FUT82_14350 ENOG4105E98 transcriptional regulator DeoR family FUT82_14355 ENOG4105DE4 1-phosphofructokinase FUT82_14360 ENOG4105DM4 PTS System FUT82_14365 ENOG4105KZ7 phosphocarrier protein hpr FUT82_14385 ENOG4105MHT Transcriptional regulator, ARSR family FUT82_14395 ENOG4105C59 p-type ATPase FUT82_14405 ENOG4107R3N Filamentation induced by cAMP protein fic FUT82_14420 ENOG4105F2I Transposase FUT82_14470 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_14510 ENOG4105VXP Protein of unknown function DUF86 FUT82_14545 ENOG4105VXP Protein of unknown function DUF86 FUT82_14555 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_14615 ENOG4105F2I Transposase FUT82_14670 ENOG4105C4R Atp-dependent dna helicase FUT82_14685 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FUT82_14695 ENOG4108ZB6 transcriptional regulator AsnC family FUT82_14700 ENOG4105CHM Aminotransferase FUT82_14705 ENOG4105CWM branched-chain amino acid transport system II carrier protein FUT82_14715 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FUT82_14720 ENOG4107QIK phosphoribosylformylglycinamidine synthase FUT82_14725 ENOG4107T2D Phosphoribosylaminoimidazolesuccinocarboxamide synthase FUT82_14735 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FUT82_14740 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FUT82_14745 ENOG4105C6E dna polymerase iii FUT82_14755 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FUT82_14770 ENOG4105JMH Nadph-dependent fmn reductase FUT82_14775 ENOG4105F2I Transposase FUT82_15015 ENOG4105CMR udp-glucose 4-epimerase FUT82_15030 ENOG4105CEP NADH dehydrogenase FUT82_15040 ENOG4105C1G acyl-Coa dehydrogenase FUT82_15045 ENOG4105BZJ Electron transfer flavoprotein FUT82_15050 ENOG4105C10 Electron transfer flavoprotein FUT82_15075 ENOG4105C37 (CBS) domain FUT82_15080 ENOG41082QW Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FUT82_15085 ENOG4105CTJ Metal Dependent Phosphohydrolase FUT82_15090 ENOG4105C9A Phoh family FUT82_15100 ENOG4105C75 arginyL-tRNA synthetase FUT82_15110 ENOG4105CEU Arginine dihydrolase FUT82_15115 ENOG4105DBV ornithine carbamoyltransferase FUT82_15120 ENOG4105C5B carbamate kinase FUT82_15130 ENOG4107QYD Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT82_15135 ENOG4105C3S Mate efflux family protein FUT82_15140 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FUT82_15150 ENOG4105VXR cytoplasmic protein FUT82_15165 ENOG4108I5U Uridine phosphorylase FUT82_15180 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FUT82_15185 ENOG4105C87 Aminotransferase class I and II FUT82_15190 ENOG4105CFC Transporter FUT82_15200 ENOG4105DNX Dna topoisomerase iv (Subunit b) FUT82_15215 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FUT82_15225 ENOG4107YY3 extracellular solute-binding protein family 1 FUT82_15235 ENOG4105C9M aspartyl-trna synthetase FUT82_15240 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) FUT82_15245 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FUT82_15255 ENOG4107QX8 SPFH domain, Band 7 family protein FUT82_15275 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FUT82_15290 ENOG4105WH1 Two component transcriptional regulator luxr family FUT82_15295 ENOG4105BZU Histidine kinase FUT82_15305 ENOG4107QP8 phosphohexose isomerase FUT82_15355 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FUT82_15365 ENOG4105CNU cell division protein FtsK FUT82_15370 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FUT82_15375 ENOG4105D82 Glutamate dehydrogenase FUT82_15395 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FUT82_15410 ENOG4105D78 K07001 NTE family protein FUT82_15415 ENOG41085BT Protein of unknown function (DUF1312) FUT82_15435 ENOG4105MB2 FUT82_15455 ENOG4105EI2 Pseudouridine synthase FUT82_15485 ENOG4106VF0 FUT82_15510 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FUT82_15520 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FUT82_15550 ENOG4109015 Biopolymer transport protein exbD tolR FUT82_15570 ENOG4106DC9 FUT82_15575 ENOG4108ZT0 50S ribosomal protein l17 FUT82_15580 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT82_15585 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FUT82_15590 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FUT82_15595 ENOG41067V7 50S ribosomal protein L36 FUT82_15600 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FUT82_15605 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FUT82_15610 ENOG41084HK 50S ribosomal protein L30 FUT82_15615 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FUT82_15620 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FUT82_15625 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FUT82_15630 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FUT82_15635 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FUT82_15640 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FUT82_15645 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FUT82_15650 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FUT82_15655 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FUT82_15660 ENOG41086S0 50s ribosomal protein l29 FUT82_15665 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FUT82_15670 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FUT82_15675 ENOG41082G4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FUT82_15680 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FUT82_15685 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FUT82_15690 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FUT82_15695 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FUT82_15700 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FUT82_15705 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FUT82_15710 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FUT82_15720 ENOG4108I7Y domain protein FUT82_15725 ENOG4105MAX Superoxide reductase FUT82_15730 ENOG4105DCI Phosphohydrolase FUT82_15755 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FUT82_15760 ENOG4105MA4 psp1 domain protein FUT82_15775 ENOG4105DR5 peptidase FUT82_15785 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FUT82_15795 ENOG4105DAP Nicotinate phosphoribosyltransferase FUT82_15810 ENOG4105FZW flagellar biosynthesis regulator FlhF FUT82_15815 ENOG4105D7B Flagellar biosynthesis protein flha FUT82_15820 ENOG4105D00 flagellar biosynthetic protein flhB FUT82_15825 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FUT82_15830 ENOG4105VS8 Flagellar biosynthetic protein fliq FUT82_15835 ENOG4105CN7 Flagellar biosynthetic protein FliP FUT82_15845 ENOG4105DD5 Flagellar motor switch protein FUT82_15850 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT82_15855 ENOG41064SM flagellar basal body-associated protein flil FUT82_15860 ENOG4107XSU flagellar motor protein motb FUT82_15865 ENOG4107R0U MotA TolQ exbB proton channel FUT82_15875 ENOG4105BZE flagellar hook protein, FlgE FUT82_15880 ENOG410822I Flagellar hook capping protein FUT82_15905 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FUT82_15915 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT82_15930 ENOG4105DPN Oligoendopeptidase f FUT82_15935 ENOG4105E0Y RtcB Protein FUT82_15940 ENOG4105CTS PTS system mannitol-specific FUT82_15945 ENOG4105E98 transcriptional regulator DeoR family FUT82_15950 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FUT82_15960 ENOG4105FB2 class II Aldolase FUT82_15970 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FUT82_15980 ENOG4105C2M dna polymerase I FUT82_16005 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FUT82_16040 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT82_16100 ENOG4105CUZ uba thif-type nad fad binding protein FUT82_16105 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FUT82_16115 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_16120 ENOG4107RCV ABC transporter, permease FUT82_16125 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT82_16140 ENOG4105C8Q Methyl-accepting chemotaxis FUT82_16145 ENOG4108V3E phosphoribosylglycinamide formyltransferase FUT82_16150 ENOG4105CXB phosphoribosylaminoimidazole synthetase FUT82_16160 ENOG4105CDY transcriptional regulatory protein FUT82_16170 ENOG4108TVT permease FUT82_16175 ENOG410877G FUT82_16180 ENOG4105RJI FUT82_16200 ENOG4108IQE Amp-dependent synthetase and ligase FUT82_16205 ENOG4105NBF ammecr1 domain protein FUT82_16240 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FUT82_16245 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT82_16265 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT82_16285 ENOG4108JJB ABC transporter FUT82_16330 ENOG4105CMT Dihydroxyacetone kinase FUT82_16340 ENOG4105D1H recombination factor protein RarA FUT82_16350 ENOG4105XBK FUT82_16355 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FUT82_16360 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) FUT82_16375 ENOG4107YVC modification (methylase) FUT82_16385 ENOG4105DFA alanine racemase domain protein FUT82_16400 ENOG4107XF7 NGG1p interacting factor 3 protein, NIF3 FUT82_16405 ENOG410835P This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FUT82_16425 ENOG4105DXN mazG family FUT82_16430 ENOG4106XCQ Inherit from COG: Pfam:DUF82 FUT82_16445 ENOG4106FP0 FUT82_16455 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein FUT82_16460 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT82_16475 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT82_16490 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FUT82_16495 ENOG4108JUB Transcriptional regulator FUT82_16505 ENOG4107XZW Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT82_16510 ENOG4105CN1 protease FUT82_16515 ENOG4108Z66 YbaK ebsC protein FUT82_16520 ENOG4105C5H ABC transporter FUT82_16835 ENOG4108Z7G MaoC domain protein dehydratase FUT82_16840 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FUT82_16845 ENOG4105CY2 Citrate transporter FUT82_16865 ENOG4105C2J ABC transporter FUT82_16870 ENOG4105CNN ABC, transporter FUT82_16875 ENOG4105CNN ABC, transporter FUT82_16915 ENOG4105DIW FeS assembly protein SUFB FUT82_16925 ENOG4105C9B Cysteine desulfurase FUT82_16930 ENOG4107YH3 SUF system FeS assembly protein, NifU family FUT82_16940 ENOG41088SP formiminoglutamate hydrolase FUT82_16950 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FUT82_16955 ENOG4105HFZ Membrane FUT82_16965 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FUT82_16975 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FUT82_16985 ENOG4108JJB ABC transporter FUT82_16990 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FUT82_16995 ENOG4108IG5 Transcriptional regulator FUT82_17000 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FUT82_17010 ENOG4108UVJ appr-1-p processing domain protein FUT82_17025 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FUT82_17030 ENOG4108UMN azlc family FUT82_17035 ENOG4105KMT branched-chain amino acid