locus-tag class description FUT79_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FUT79_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FUT79_00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FUT79_00020 ENOG4106C4Y Protein of unknown function (DUF721) FUT79_00030 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT79_00035 ENOG4105C8J )-transporter FUT79_00040 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT79_00045 ENOG4105EAD ABC transporter FUT79_00060 ENOG4105CIZ coA-substrate-specific enzyme activase FUT79_00285 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FUT79_00290 ENOG4105C34 Pseudouridine synthase FUT79_00295 ENOG4105CIN aminoacyl-histidine dipeptidase FUT79_00300 ENOG4108IUW ABC transporter FUT79_00320 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) FUT79_00330 ENOG4108ZVA radical SAM domain protein FUT79_00340 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) FUT79_00345 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FUT79_00350 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FUT79_00375 ENOG4105E98 transcriptional regulator DeoR family FUT79_00385 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT79_00390 ENOG4105CT4 transporter FUT79_00395 ENOG4105CNT hydrolase family 2 FUT79_00400 ENOG4105D2H Uronic isomerase FUT79_00405 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT79_00415 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT79_00420 ENOG4105DEI Mannitol dehydrogenase FUT79_00425 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FUT79_00435 ENOG4105II7 pyrroline-5-carboxylate reductase FUT79_00440 ENOG4105F4G Membrane FUT79_00455 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FUT79_00460 ENOG4105VVB FUT79_00465 ENOG4106KG8 FUT79_00470 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FUT79_00475 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) FUT79_00485 ENOG4108EKI Dehydrogenase FUT79_00505 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT79_00560 ENOG4105C3S Mate efflux family protein FUT79_00565 ENOG4105C75 arginyL-tRNA synthetase FUT79_00580 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_00585 ENOG4107RFY SbcCD D subunit FUT79_00590 ENOG4105EYH Exonuclease FUT79_00600 ENOG4105C5H ABC transporter FUT79_00605 ENOG4108Z66 YbaK ebsC protein FUT79_00610 ENOG4105CN1 protease FUT79_00615 ENOG4107XZW Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT79_00625 ENOG4108JUB Transcriptional regulator FUT79_00630 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FUT79_00645 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT79_00660 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT79_00665 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein FUT79_00675 ENOG4106FP0 FUT79_00690 ENOG4105D1H recombination factor protein RarA FUT79_00700 ENOG4105XBK FUT79_00705 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FUT79_00710 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) FUT79_00725 ENOG4107YVC modification (methylase) FUT79_00735 ENOG4105DFA alanine racemase domain protein FUT79_00750 ENOG4107XF7 NGG1p interacting factor 3 protein, NIF3 FUT79_00755 ENOG410835P This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FUT79_00775 ENOG4105DXN mazG family FUT79_00780 ENOG4106XCQ Inherit from COG: Pfam:DUF82 FUT79_00795 ENOG4105DQ6 Transposase FUT79_00805 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_00820 ENOG4108Z4J Cytidine monophosphate kinase FUT79_00830 ENOG4105DFU Cell wall formation (By similarity) FUT79_00840 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FUT79_00855 ENOG4105DQ6 Transposase FUT79_00885 ENOG4105DQ6 Transposase FUT79_00910 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FUT79_00920 ENOG4108JE9 extracellular solute-binding protein family 1 FUT79_00935 ENOG4105BZU Histidine kinase FUT79_00940 ENOG4105BZU Histidine kinase FUT79_00960 ENOG4108UHU Aldolase FUT79_00965 ENOG4105C37 (CBS) domain FUT79_00970 ENOG4108JU6 CBS domain protein FUT79_00980 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_00995 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FUT79_01000 ENOG4107V9H nitrite transporter FUT79_01015 ENOG4105ZAM anti-sigma-28 factor flgm family protein FUT79_01020 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FUT79_01030 ENOG4105CSM endonuclease III FUT79_01035 ENOG4105C8J )-transporter FUT79_01040 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT79_01050 ENOG4107QMH DNA methylase FUT79_01055 ENOG4105D8D Type III FUT79_01065 ENOG4105DQ6 Transposase FUT79_01080 ENOG4108DBC nitroreductase FUT79_01085 ENOG4105C3J Cysteine desulfurase FUT79_01100 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FUT79_01105 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FUT79_01135 ENOG4105DAN ATP-dependent protease FUT79_01160 ENOG4105CGH 5'-nucleotidase FUT79_01170 ENOG4105DZW Dipeptidase FUT79_01175 ENOG4105CV8 reductase FUT79_01190 ENOG4105DRR Transcriptional regulator, GntR family FUT79_01210 ENOG4105E0M Sulfatase FUT79_01215 ENOG4105E0M Sulfatase FUT79_01245 ENOG4105D6S protein involved in catabolism of external DNA FUT79_01255 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FUT79_01265 ENOG410854D Required for maturation of 30S ribosomal subunits (By similarity) FUT79_01270 ENOG4105CHV Transcription elongation factor NusA FUT79_01275 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FUT79_01285 ENOG41080JB Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FUT79_01290 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FUT79_01295 ENOG4105DTN riboflavin biosynthesis protein ribF FUT79_01300 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FUT79_01305 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FUT79_01310 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FUT79_01325 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FUT79_01335 ENOG4105DRS transport system, permease FUT79_01355 ENOG4105F2I Transposase FUT79_01370 ENOG4105DQ6 Transposase FUT79_01375 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FUT79_01385 ENOG4105C22 threonyL-tRNA synthetase FUT79_01390 ENOG4105CB5 ATP-dependent DNA helicase recG FUT79_01400 ENOG4105CGH 5'-nucleotidase FUT79_01415 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FUT79_01435 ENOG4105BZ1 (ABC) transporter FUT79_01440 ENOG4105BZ1 (ABC) transporter FUT79_01460 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT79_01485 ENOG4105G6Z alkaline phosphatase FUT79_01505 ENOG4105EPW hflc protein FUT79_01510 ENOG4107RIZ hflk protein FUT79_01520 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT79_01530 ENOG4107R2U Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FUT79_01535 ENOG4106W1H FUT79_01545 ENOG4105CDA abc transporter atp-binding protein FUT79_01550 ENOG4105EAD ABC transporter FUT79_01555 ENOG4108HW3 (ABC) transporter FUT79_01565 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FUT79_01580 ENOG4107S6Z Na H antiporter FUT79_01585 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FUT79_01595 ENOG4105C0D helicase FUT79_01605 ENOG4105KRQ Addiction module toxin, Txe YoeB family FUT79_01615 ENOG4108HU6 Metal dependent phosphohydrolase FUT79_01625 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT79_01630 ENOG4107XHD Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT79_01650 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT79_01660 ENOG4105G9E FUT79_01665 ENOG4108J59 Extracellular solute-binding protein, family 5 FUT79_01670 ENOG4106FRC FUT79_01675 ENOG4105JTB FUT79_01680 ENOG4108V2B Flagellar filament outer layer protein FUT79_01690 ENOG4105D2N Aldolase FUT79_01710 ENOG4107SFZ crispr-associated protein FUT79_01730 ENOG41067MG lrgb family FUT79_01740 ENOG4108ZV0 ABC transporter, permease FUT79_01745 ENOG4108TWB ABC transporter (Permease FUT79_01755 ENOG4108SSC basic membrane FUT79_01770 ENOG41084P6 50S ribosomal protein l28 FUT79_01780 ENOG4105CQ7 ATP-dependent helicase FUT79_01790 ENOG4105C5I Dehydrogenase FUT79_01795 ENOG4105D6U Sodium Glutamate Symporter FUT79_01805 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein FUT79_01810 ENOG4105D9Q decarboxylase (Beta subunit) FUT79_01815 ENOG4105DMN coenzyme A transferase FUT79_01820 ENOG4107UHT Glutaconate CoA-transferase FUT79_01825 ENOG4107QX3 carboxylase FUT79_01830 ENOG4105D6U Sodium Glutamate Symporter FUT79_01840 ENOG4105CMH dehydratase FUT79_01845 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FUT79_01865 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT79_01885 ENOG4105C7N Xanthine uracil vitamin C permease FUT79_01890 ENOG4108UIC UPF0340 protein FUT79_01915 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_01930 ENOG41067S9 phage shock protein C, PspC FUT79_01950 ENOG4105CY0 Metallo-Beta-Lactamase FUT79_01955 ENOG4105C2N RNA methyltransferase TrmH family group 3 FUT79_01965 ENOG4108IJ2 phosphate acetyltransferase FUT79_01970 ENOG4107GWN repeat protein FUT79_01975 ENOG4105BZU Histidine kinase FUT79_01985 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FUT79_01995 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FUT79_02000 ENOG4108KS2 transglutaminase domain protein FUT79_02015 ENOG4105C8N cysteinyl-tRNA synthetase FUT79_02020 ENOG4107QWW Cell wall formation (By similarity) FUT79_02025 ENOG4105IJJ transcriptional regulator, crp fnr family FUT79_02040 ENOG4105BZU Histidine kinase FUT79_02045 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FUT79_02055 ENOG4105DQ6 Transposase FUT79_02065 ENOG4109031 FUT79_02070 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FUT79_02315 ENOG4106VF0 FUT79_02345 ENOG4105EI2 Pseudouridine synthase FUT79_02365 ENOG4105MB2 FUT79_02385 ENOG41085BT Protein of unknown function (DUF1312) FUT79_02390 ENOG4105D78 K07001 NTE family protein FUT79_02405 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FUT79_02410 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_02415 ENOG4105D82 Glutamate dehydrogenase FUT79_02420 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FUT79_02425 ENOG4105CNU cell division protein FtsK FUT79_02435 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FUT79_02480 ENOG4105F2I Transposase FUT79_02500 ENOG4107QP8 phosphohexose isomerase FUT79_02515 ENOG4105F2I Transposase FUT79_02525 ENOG4105BZU Histidine kinase FUT79_02530 ENOG4105WH1 Two component transcriptional regulator luxr family FUT79_02545 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FUT79_02565 ENOG4107QX8 SPFH domain, Band 7 family protein FUT79_02575 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FUT79_02580 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) FUT79_02585 ENOG4105C9M aspartyl-trna synthetase FUT79_02595 ENOG4107YY3 extracellular solute-binding protein family 1 FUT79_02605 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FUT79_02615 ENOG4105DNX Dna topoisomerase iv (Subunit b) FUT79_02630 ENOG4105CFC Transporter FUT79_02635 ENOG4105C87 Aminotransferase class I and II FUT79_02640 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FUT79_02655 ENOG4108I5U Uridine phosphorylase FUT79_02670 ENOG4105VXR cytoplasmic protein FUT79_02680 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FUT79_02685 ENOG4105C3S Mate efflux family protein FUT79_02690 ENOG4107QYD Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT79_02700 ENOG4105C5B carbamate kinase FUT79_02705 ENOG4105DBV ornithine carbamoyltransferase FUT79_02710 ENOG4105CEU Arginine dihydrolase FUT79_02720 ENOG4105C75 arginyL-tRNA synthetase FUT79_02730 ENOG4105C9A Phoh family FUT79_02735 ENOG4105CTJ Metal Dependent Phosphohydrolase FUT79_02740 ENOG41082QW Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FUT79_02745 ENOG4105C37 (CBS) domain FUT79_02770 ENOG4105C10 Electron transfer flavoprotein FUT79_02775 ENOG4105BZJ Electron transfer flavoprotein FUT79_02780 ENOG4105C1G acyl-Coa dehydrogenase FUT79_02790 ENOG4105CEP NADH dehydrogenase FUT79_02805 ENOG4105CMR udp-glucose 4-epimerase FUT79_02820 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_02825 ENOG4105JMH Nadph-dependent fmn reductase FUT79_02840 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FUT79_02850 ENOG4105C6E dna polymerase iii FUT79_02855 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FUT79_02860 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FUT79_02870 ENOG4107T2D Phosphoribosylaminoimidazolesuccinocarboxamide synthase FUT79_02875 ENOG4107QIK phosphoribosylformylglycinamidine synthase FUT79_02880 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FUT79_02890 ENOG4105CWM branched-chain amino acid transport system II carrier protein FUT79_02895 ENOG4105CHM Aminotransferase FUT79_02900 ENOG4108ZB6 transcriptional regulator AsnC family FUT79_02910 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FUT79_02925 ENOG4105C4R Atp-dependent dna helicase FUT79_02965 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03005 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_03010 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03030 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_03100 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_03115 ENOG4107R3N Filamentation induced by cAMP protein fic FUT79_03125 ENOG4105C59 p-type ATPase FUT79_03135 ENOG4105MHT Transcriptional regulator, ARSR family FUT79_03175 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03185 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03190 ENOG4107EFR Flavocytochrome c FUT79_03215 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03230 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_03270 ENOG41083HS Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FUT79_03275 ENOG4105DFD Na H antiporter FUT79_03310 ENOG4105I03 Flagellin FUT79_03315 ENOG4105C6N Formate acetyltransferase FUT79_03320 ENOG4105F1A Pyruvate formate-lyase FUT79_03345 ENOG4105CBS Chea signal transduction histidine kinase FUT79_03350 ENOG4105YFD chemotaxis, protein FUT79_03360 ENOG4107Z9R response regulator FUT79_03370 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FUT79_03380 ENOG4106GEY FUT79_03385 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FUT79_03390 ENOG4106S0F FUT79_03405 ENOG4108RY1 ATP synthase, subunit E FUT79_03415 ENOG4107RVI Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) FUT79_03420 ENOG4107RQX Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit FUT79_03425 ENOG4108WBK V-type ATP synthase subunit D FUT79_03430 ENOG4107U1W v-type ATP synthase subunit I FUT79_03440 ENOG4107QNB Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FUT79_03445 ENOG4105WD1 Membrane FUT79_03450 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FUT79_03470 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FUT79_03475 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FUT79_03495 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FUT79_03500 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FUT79_03505 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FUT79_03510 ENOG4108IQE Amp-dependent synthetase and ligase FUT79_03520 ENOG4107R5H iron (metal) dependent repressor, dtxr family FUT79_03525 ENOG4107RBD ABC, transporter FUT79_03530 ENOG4107RPQ ABC transporter FUT79_03535 ENOG4105DIK (ABC) transporter FUT79_03540 ENOG4107SIG periplasmic solute binding protein FUT79_03550 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT79_03555 ENOG4105C2J ABC transporter FUT79_03560 ENOG4107R2W ABC transporter, permease FUT79_03780 ENOG4106N2C FUT79_03785 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FUT79_03805 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_03810 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FUT79_03815 ENOG4107QNG Phosphoribosylglycinamide synthetase FUT79_03820 ENOG4105DC1 bifunctional purine biosynthesis protein purh FUT79_03840 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FUT79_03845 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT79_03850 ENOG4108HM4 ABC transporter FUT79_03855 ENOG4105D38 putrescine abc transporter FUT79_03860 ENOG4105F38 ABC transporter, permease FUT79_03865 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_03870 ENOG4105C5X domain protein FUT79_03880 ENOG41062BZ domain protein FUT79_03890 ENOG4107QW4 alcohol dehydrogenase FUT79_03900 ENOG4105K4H Nlp p60 protein FUT79_03905 ENOG4105CEY Amp-dependent synthetase and ligase FUT79_03910 ENOG41083CW dedA protein FUT79_03915 ENOG4107QMG Nad synthetase FUT79_03925 ENOG410684W FUT79_03930 ENOG4105KG3 cytidine deaminase FUT79_03935 ENOG4105C1A potassium transporter peripheral membrane FUT79_03940 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FUT79_03975 ENOG4108UT2 hemolysin iii FUT79_03995 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_04000 ENOG4108JA2 transcriptioN-repair coupling factor FUT79_04010 ENOG4105CJW magnesium transporter FUT79_04015 ENOG4105D6E homoserine dehydrogenase FUT79_04020 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FUT79_04025 ENOG4105CVG Homoserine O-transsuccinylase FUT79_04035 ENOG4105DR4 Methyltransferase FUT79_04040 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FUT79_04050 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FUT79_04055 ENOG4108JQ7 (ABC) transporter FUT79_04070 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT79_04080 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT79_04085 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FUT79_04100 ENOG4105CKI cobalamin synthesis protein FUT79_04110 ENOG4105E98 transcriptional regulator DeoR family FUT79_04120 ENOG4105D7K pfkb domain protein FUT79_04125 ENOG4105D2N Aldolase FUT79_04130 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT79_04135 ENOG4105CI2 imidazolone-5-propionate hydrolase FUT79_04170 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FUT79_04180 ENOG4105C1J atp-dependent rna helicase FUT79_04200 ENOG4105CJ1 ABC, transporter FUT79_04215 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT79_04220 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FUT79_04225 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FUT79_04230 ENOG4105C2J ABC transporter FUT79_04235 ENOG4105CNN ABC, transporter FUT79_04245 ENOG4105DJ0 Poly(A) Polymerase FUT79_04250 ENOG4105CUY Mechanosensitive ion channel FUT79_04265 ENOG41090KZ FUT79_04285 ENOG4105K6T rare lipoprotein A FUT79_04295 ENOG4105F8V Hydrolase, tatD family FUT79_04300 ENOG41081GK CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase FUT79_04305 ENOG4105K63 Thioredoxin FUT79_04310 ENOG4105IJJ transcriptional regulator, crp fnr family FUT79_04330 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FUT79_04340 ENOG4107NGC Flagellar filament outer layer protein FUT79_04350 ENOG41086BH Binds directly to 16S ribosomal RNA (By similarity) FUT79_04355 ENOG41083IJ DNA-binding protein FUT79_04365 ENOG4107RI4 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT79_04375 ENOG4105CEV competence damage-inducible protein FUT79_04380 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FUT79_04385 ENOG41082DI 50s ribosomal protein l31 FUT79_04400 ENOG4105CA9 Pyruvate kinase FUT79_04415 ENOG4105DRS transport system, permease FUT79_04435 ENOG4105F2I Transposase FUT79_04445 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FUT79_04460 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FUT79_04465 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FUT79_04475 ENOG4108R6K riboflavin synthase, subunit alpha FUT79_04480 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FUT79_04495 ENOG4105C5H ABC transporter FUT79_04500 ENOG4105I76 (LipO)protein FUT79_04515 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FUT79_04525 ENOG4107RJF diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) FUT79_04530 ENOG41082Y9 Single-strand binding protein FUT79_04545 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT79_04550 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_04560 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT79_04565 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT79_04580 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FUT79_04595 ENOG4105CGP Urocanate hydratase FUT79_04610 ENOG4105D07 Signal peptide peptidase, SppA FUT79_04615 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FUT79_04620 ENOG4105C3F Signal peptidase i FUT79_04630 ENOG4105X1A FUT79_04635 ENOG41062Z1 FUT79_04640 ENOG4105DZP Membrane-associated zinc metalloprotease FUT79_04645 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FUT79_04650 ENOG4105KNE Phosphatidate cytidylyltransferase FUT79_04655 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FUT79_04660 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FUT79_04665 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FUT79_04670 ENOG4105CE9 30S ribosomal protein S2 FUT79_04685 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT79_04690 ENOG4107RBB ABC transporter, permease FUT79_04695 ENOG4107RBB ABC transporter, permease FUT79_04700 ENOG4105C1J atp-dependent rna helicase FUT79_04705 ENOG4105CJ1 ABC, transporter FUT79_04725 ENOG4105BZU Histidine kinase FUT79_04745 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT79_04770 ENOG4105CE1 Ferrous iron transport protein b FUT79_04775 ENOG4107GGS FUT79_04785 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FUT79_04805 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT79_04890 ENOG4105KT7 mgtC SapB transporter FUT79_04895 ENOG4106ARS FUT79_04910 ENOG4107R21 site-determining protein FUT79_04920 ENOG4107WGG Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FUT79_04925 ENOG4105DF5 DNA topoisomerase IV, subunit A FUT79_04940 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FUT79_04945 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT79_04950 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FUT79_04985 ENOG4105BZU Histidine kinase FUT79_04995 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FUT79_05000 ENOG4105F8V Hydrolase, tatD family FUT79_05015 ENOG4108NF7 phage-type endonuclease FUT79_05035 ENOG4108PNI recT protein FUT79_05100 ENOG4105Z8H single-stranded DNA-binding protein FUT79_05385 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT79_05390 ENOG4105WJX transcriptional regulator MERR family FUT79_05400 ENOG4106QD2 FUT79_05405 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FUT79_05410 ENOG4105C3F Signal peptidase i FUT79_05415 ENOG4105CSA Coproporphyrinogen iii oxidase FUT79_05420 ENOG4106YRG FUT79_05425 ENOG41084AY Binds together with S18 to 16S ribosomal RNA (By similarity) FUT79_05430 ENOG4105Z8H single-stranded DNA-binding protein FUT79_05435 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FUT79_05440 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FUT79_05445 ENOG4105CDU Replicative dna helicase FUT79_05480 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT79_05485 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT79_05520 ENOG4105DM4 PTS System FUT79_05525 ENOG41077G2 FUT79_05535 ENOG4105MPN Membrane FUT79_05545 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FUT79_05550 ENOG4105CFG Acts as a chaperone (By similarity) FUT79_05555 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FUT79_05560 ENOG4108JIP Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity) FUT79_05565 ENOG4107RVI Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) FUT79_05585 ENOG4107WUB V-type ATPase 116 kDa subunit FUT79_05600 ENOG4105DM4 PTS System FUT79_05605 ENOG4106447 Preprotein translocase subunit SecG FUT79_05620 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FUT79_05625 ENOG4105DD7 kinase (PfkB family FUT79_05630 ENOG4107YM1 mraZ protein FUT79_05635 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FUT79_05645 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FUT79_05650 ENOG4105CNI cell division protein FtsW FUT79_05655 ENOG410812A polypeptide-transport-associated domain protein, FtsQ-type FUT79_05660 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FUT79_05665 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FUT79_05670 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT79_05680 ENOG4105C79 DNA protecting protein DprA FUT79_05685 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FUT79_05690 ENOG4108I7H Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT79_05695 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FUT79_05700 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FUT79_05710 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FUT79_05715 ENOG4108ZC9 flagellar basal-body rod protein flgc FUT79_05720 ENOG41069WH flagellar hook-basal body complex FUT79_05725 ENOG4107U2N Flagellar M-ring protein FUT79_05730 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT79_05735 ENOG4105W2B Flagellar assembly protein FUT79_05740 ENOG4108JIR Flagellum-specific ATP synthase FUT79_05755 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FUT79_05770 ENOG4105Q84 sucrose synthase FUT79_05795 ENOG4105C6F GntR Family Transcriptional Regulator FUT79_05830 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FUT79_05835 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FUT79_05840 ENOG41090QR FUT79_05855 ENOG4105CH2 amidohydrolase FUT79_05870 ENOG4105CSA Coproporphyrinogen iii oxidase FUT79_05880 ENOG4108V1T peptidylprolyl cis-trans isomerase FUT79_05915 ENOG4108RVA ribokinase FUT79_05920 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FUT79_05925 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FUT79_05935 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_05965 ENOG4105W5Q DNA repair protein (RadC FUT79_05995 ENOG4105C0H protease FUT79_06000 ENOG4105CE4 GlcNAc 6-P deacetylase FUT79_06010 ENOG4108IXY short-chain dehydrogenase reductase FUT79_06015 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FUT79_06025 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FUT79_06040 ENOG4107QSA Oxaloacetate decarboxylase FUT79_06045 ENOG4105D9Q decarboxylase (Beta subunit) FUT79_06050 ENOG4105EAB amino acid AbC transporter FUT79_06055 ENOG4108HW3 (ABC) transporter FUT79_06060 ENOG4108120 Pasta domain protein FUT79_06070 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FUT79_06075 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FUT79_06080 ENOG4106BN6 FUT79_06085 ENOG4108JDX DNA polymerase iii, epsilon subunit FUT79_06100 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase FUT79_06105 ENOG4106GZE FUT79_06160 ENOG4105CVR type I restriction-modification system FUT79_06190 ENOG4105II7 pyrroline-5-carboxylate reductase FUT79_06205 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FUT79_06210 ENOG4106XJW FUT79_06225 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT79_06245 ENOG4105CFP Peptidase U32 FUT79_06260 ENOG4108NVR Methyl-accepting chemotaxis FUT79_06280 ENOG4107W7Y Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FUT79_06290 ENOG41090Q2 FUT79_06325 ENOG4105WN5 stage II sporulation protein FUT79_06335 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FUT79_06345 ENOG4105K46 50S ribosomal protein l27 FUT79_06350 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FUT79_06355 ENOG4107X4V Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FUT79_06400 ENOG4107R39 (ABC) transporter FUT79_06405 ENOG4107SJW iron permease, FTR1 FUT79_06410 ENOG4108SDV Periplasmic Protein FUT79_06425 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT79_06440 ENOG4105C19 ABC transporter FUT79_06460 ENOG4105I7V membrAne FUT79_06465 ENOG4105EA8 2-Nitropropane dioxygenase FUT79_06470 ENOG4105ESV Glycosyl transferase, family 4 FUT79_06490 ENOG4105DR5 peptidase FUT79_06500 ENOG4108JQC penicillin-binding protein 1A FUT79_06510 ENOG41082BE ankyrin repeat-containing protein FUT79_06515 ENOG4105Z8J FUT79_06530 ENOG4106AG2 FUT79_06540 ENOG41068FD FUT79_06545 ENOG4105CU9 asparagine synthetase A FUT79_06555 ENOG4108V0P LemA family FUT79_06565 ENOG4105HA9 of methanol dehydrogenase type FUT79_06580 ENOG41061XC FUT79_06595 ENOG4107R3E Citrate transporter FUT79_06600 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FUT79_06615 ENOG4105CGA flagellar basal-body rod protein FlgG FUT79_06625 ENOG4108S3Y transcriptional regulator FUT79_06630 ENOG4105C5Y PTS System FUT79_06635 ENOG4108HCJ Hydrolase FUT79_06640 ENOG4105CS2 ec 3.2.1.21 FUT79_06655 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_06660 ENOG4105MQ3 flagellar protein FliS FUT79_06665 ENOG4106VWR FUT79_06670 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FUT79_06675 ENOG4106B9X FUT79_06680 ENOG4105DR9 pseudouridine synthase FUT79_06685 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FUT79_06690 ENOG4105BZU Histidine kinase FUT79_06715 ENOG41083MR nifu domain-containing protein FUT79_06725 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FUT79_06730 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_06735 ENOG4105BZU Histidine kinase FUT79_06740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FUT79_06745 ENOG4108UTW Plays a role in the regulation of phosphate uptake FUT79_06750 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FUT79_06755 ENOG4105E2Z phosphate ABC transporter (Permease FUT79_06760 ENOG4105C8U phosphate abc transporter FUT79_06765 ENOG4105CVA phosphate FUT79_06795 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT79_06800 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT79_06830 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) FUT79_06840 ENOG4105CHY citrate lyase, alpha FUT79_06860 ENOG4107QMH DNA methylase FUT79_06880 ENOG4108JJB ABC transporter FUT79_06905 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT79_06970 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT79_07035 ENOG4105NI8 Cytosine-specific methyltransferase FUT79_07055 ENOG4105BZ1 (ABC) transporter FUT79_07145 ENOG4105DXX methyltransferase FUT79_07180 ENOG4105F2I Transposase FUT79_07185 ENOG4105E0A ABC, transporter FUT79_07190 ENOG4105EHG Permease protein FUT79_07195 ENOG4105BZ1 (ABC) transporter FUT79_07200 ENOG4105BZ1 (ABC) transporter FUT79_07255 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT79_07280 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FUT79_07285 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FUT79_07290 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FUT79_07295 ENOG4105DR5 peptidase FUT79_07305 ENOG4105BZ1 (ABC) transporter FUT79_07310 ENOG4105BZ1 (ABC) transporter FUT79_07315 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FUT79_07345 ENOG41062VP FUT79_07360 ENOG4105BZ1 (ABC) transporter FUT79_07365 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FUT79_07370 ENOG41071ED FUT79_07385 ENOG4106UUF FUT79_07400 ENOG4105SXG FUT79_07405 ENOG4105ZF0 Lipoprotein FUT79_07410 ENOG4105C26 Dehydrogenase FUT79_07415 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT79_07420 ENOG4105CNN ABC, transporter FUT79_07425 ENOG4105C2J ABC transporter FUT79_07430 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FUT79_07480 ENOG4105C6Z Gluconate FUT79_07485 ENOG4105BZW Glycerate kinase FUT79_07490 ENOG4108MIC Mg-protoporphyrin IX methyl transferase FUT79_07495 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FUT79_07500 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT79_07515 ENOG4108TSD Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT79_07530 ENOG4105ZFX FUT79_07540 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FUT79_07560 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FUT79_07565 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FUT79_07570 ENOG4108UW5 maltose o-acetyltransferase FUT79_07580 ENOG4105CTZ aminopeptidase c FUT79_07600 ENOG4105D98 threonine synthase FUT79_07620 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT79_07630 ENOG4105K8N protein family UPF0079, ATPase FUT79_07635 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FUT79_07655 ENOG41071ZZ FUT79_07670 ENOG4105C0P Mg chelatase subunit ChlI FUT79_07680 ENOG4105I03 Flagellin FUT79_07685 ENOG4105I03 Flagellin FUT79_07695 ENOG4107VE5 flagellar hook-associated protein FUT79_07700 ENOG4106SAP FUT79_07720 ENOG4105EI2 Pseudouridine synthase FUT79_07735 ENOG41089XN FUT79_07745 ENOG4105C5H ABC transporter FUT79_07745 ENOG4105C5H ABC transporter FUT79_07755 ENOG4108UN4 phage SPO1 DNA polymerase-related protein FUT79_07760 ENOG4105C25 Primosomal protein n' FUT79_07775 ENOG41066A3 ATP guanido phosphotransferase FUT79_07790 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT79_07805 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FUT79_07810 ENOG4106MPK FUT79_07840 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FUT79_07845 ENOG4108626 Racemase FUT79_07850 ENOG4106PKC pyridoxal phosphate binding FUT79_07865 ENOG4106M0N transport system permease protein FUT79_07870 ENOG4105MUZ Protein of unknown function DUF2620 FUT79_07890 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FUT79_07910 ENOG4105CH2 amidohydrolase FUT79_07915 ENOG4105FAV ABC, transporter FUT79_07920 ENOG4105FDK ABC transporter FUT79_07925 ENOG4105DSE periplasmic solute binding protein FUT79_07935 ENOG4106SUR Protein of unknown function DUF115 FUT79_07945 ENOG4108RAC Rubrerythrin FUT79_07970 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FUT79_07980 ENOG4105EJQ L-serine dehydratase FUT79_07985 ENOG4108ESY Metal dependent phosphohydrolase FUT79_07990 ENOG41063XV FUT79_07995 ENOG4107MD5 glycoside hydrolase, family FUT79_08015 ENOG4105CJN penicillin-binding protein FUT79_08025 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FUT79_08040 ENOG4107R05 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT79_08045 ENOG41080VC Galactokinase (EC 2.7.1.6) FUT79_08050 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FUT79_08065 ENOG4106R77 FUT79_08075 ENOG4105DR5 peptidase FUT79_08090 ENOG4108NF7 phage-type endonuclease FUT79_08110 ENOG4108PNI recT protein FUT79_08175 ENOG4105Z8H single-stranded DNA-binding protein FUT79_08460 ENOG4105DR5 peptidase FUT79_08465 ENOG4105BZ1 (ABC) transporter FUT79_08470 ENOG4105DWF phosphomethylpyrimidine kinase FUT79_08475 ENOG4105C8T Leucyl-tRNA synthetase FUT79_08495 ENOG4106JH4 FUT79_08500 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FUT79_08505 ENOG4105DN3 alpha-2-macroglobulin domain protein FUT79_08510 ENOG4108JQB penicillin-binding protein 1C FUT79_08515 ENOG4107QJE Chromosome Partitioning Protein FUT79_08520 ENOG4105FA0 parb-like partition protein FUT79_08530 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FUT79_08540 ENOG4105E9H Lytic Murein transglycosylase FUT79_08555 ENOG4105MJ2 Competence protein FUT79_08590 ENOG4105WH1 Two component transcriptional regulator luxr family FUT79_08605 ENOG4105BZ8 glutamate synthase FUT79_08610 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein FUT79_08615 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT79_08630 ENOG4105E5D amino acid FUT79_08670 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FUT79_08675 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FUT79_08710 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FUT79_08720 ENOG41085YX 50S ribosomal protein L32 FUT79_08725 ENOG41084E5 Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FUT79_08730 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FUT79_08735 ENOG4105F2I Transposase FUT79_08740 ENOG4105F0S class B acid phosphatase FUT79_08750 ENOG4105FE9 pseudouridine synthase FUT79_08755 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FUT79_08760 ENOG4105MBR gumn family FUT79_08765 ENOG4105C31 Tryptophanyl-tRNA synthetase FUT79_08775 ENOG4105CZV ABC transporter FUT79_08785 ENOG4107QJD pyruvate phosphate dikinase FUT79_08790 ENOG4108SXE FUT79_08795 ENOG41073RW Cytoplasmic filament protein A FUT79_08800 ENOG4105YQK von Willebrand factor type A domain FUT79_08815 ENOG4105DK7 lysyl-tRNA synthetase FUT79_08830 ENOG4106C6A Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FUT79_08835 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT79_08840 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT79_08845 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FUT79_08850 ENOG4108VZM 50s ribosomal protein L10 FUT79_08855 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) FUT79_08860 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FUT79_08865 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FUT79_08880 ENOG41084ED 50S ribosomal protein L33 FUT79_08890 ENOG4108Z29 Flavodoxin FUT79_08905 ENOG4105CY2 Citrate transporter FUT79_08910 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FUT79_08915 ENOG4108Z7G MaoC domain protein dehydratase FUT79_09145 ENOG4105CEC DNA methylase N-4 N-6 FUT79_09215 ENOG4105M7P phage repressor FUT79_09230 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FUT79_09245 ENOG4105KZ7 phosphocarrier protein hpr FUT79_09250 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FUT79_09265 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FUT79_09270 ENOG4107S1W 4-alpha-glucanotransferase FUT79_09280 ENOG4105VG0 50S ribosomal protein l34 FUT79_09295 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FUT79_09310 ENOG4107XH4 PPIases accelerate the folding of proteins (By similarity) FUT79_09325 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT79_09330 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FUT79_09340 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_09350 ENOG4107RBJ symporter FUT79_09380 ENOG4105C22 threonyL-tRNA synthetase FUT79_09415 ENOG4105DTI Phosphonopyruvate decarboxylase FUT79_09420 ENOG4107STF Involved in phosphonate degradation (By similarity) FUT79_09425 ENOG4105EE0 oxidoreductase FUT79_09455 ENOG4105J5G Transferase hexapeptide repeat containing protein FUT79_09465 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT79_09475 ENOG4105C1B dTDP-glucose 4-6-dehydratase FUT79_09480 ENOG4105PSV Polysaccharide Biosynthesis Protein FUT79_09505 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FUT79_09510 ENOG4107QQG Dehydrogenase FUT79_09520 ENOG4105DMT epimerase dehydratase FUT79_09540 ENOG4105C1B dTDP-glucose 4-6-dehydratase FUT79_09555 ENOG4105KME endoribonuclease L-psp FUT79_09560 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FUT79_09565 ENOG4105FA0 parb-like partition protein FUT79_09570 ENOG4108QUE repeat-containing protein FUT79_09580 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FUT79_09585 ENOG4105E2D ec 3.2.1.52 FUT79_09595 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FUT79_09605 ENOG4106SWD FUT79_09615 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT79_09620 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FUT79_09635 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FUT79_09640 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FUT79_09645 ENOG41067XK integral membrane protein FUT79_09650 ENOG4105C0B DNA polymerase III (alpha subunit) FUT79_09655 ENOG4105N98 Capsule biosynthesis protein capB FUT79_09670 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FUT79_09695 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FUT79_09700 ENOG4106TCE FUT79_09710 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FUT79_09720 ENOG4105W0I repeat-containing protein FUT79_09725 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT79_09730 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FUT79_09745 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FUT79_09750 ENOG4105EAM Na Pi-cotransporter FUT79_09765 ENOG4105FEU K -dependent Na -Ca exchanger FUT79_09775 ENOG41081IW Inherit from COG: Membrane FUT79_09785 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT79_09800 ENOG4105DUA (citrate (pro-3S)-lyase ligase FUT79_09810 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FUT79_09840 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FUT79_09850 ENOG4105D48 metallophosphoesterase FUT79_09855 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT79_09860 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) FUT79_09870 ENOG4108RZE Tetr family transcriptional regulator FUT79_09880 ENOG4108M1M outer membrane lipoprotein-sorting protein FUT79_09890 ENOG4108YZY peptidylprolyl cis-trans isomerase FUT79_09900 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FUT79_09905 ENOG410680E Flagellar protein FUT79_09910 ENOG4105CGA flagellar basal-body rod protein FlgG FUT79_09915 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FUT79_09930 ENOG4105C98 muts2 protein FUT79_09935 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FUT79_09940 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FUT79_09950 ENOG4108346 Beta-lactamase domain protein FUT79_09960 ENOG41084YP 30S ribosomal protein S21 FUT79_09965 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FUT79_09970 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FUT79_09975 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT79_09995 ENOG4105CE1 Ferrous iron transport protein b FUT79_10045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT79_10050 ENOG4105BZU Histidine kinase FUT79_10055 ENOG4107QRG dna polymerase iii FUT79_10060 ENOG4107JR8 Colicin v production protein FUT79_10065 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FUT79_10090 ENOG4105D48 metallophosphoesterase FUT79_10100 ENOG4105EAH synthase FUT79_10115 ENOG4105HCZ FUT79_10120 ENOG4105CTQ phosphohexokinase FUT79_10125 ENOG4105DQ6 Transposase FUT79_10150 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FUT79_10165 ENOG4105C5S asparaginyl-tRNA synthetase FUT79_10170 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_10185 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT79_10190 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FUT79_10195 ENOG4105W87 Cbs domain FUT79_10200 ENOG4108IV0 ABC, transporter FUT79_10205 ENOG4105C0Z ABC transporter FUT79_10210 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FUT79_10215 ENOG4105C32 Amino acid ABC transporter (Permease) FUT79_10225 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT79_10230 ENOG41068UM RNA Polymerase FUT79_10245 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_10260 ENOG4106U5D Septum formation initiator FUT79_10265 ENOG410698I FUT79_10275 ENOG4105X4X Protein of unknown function DUF115 FUT79_10280 ENOG41090QV Protein of unknown function DUF115 FUT79_10310 ENOG4105DJV ribulose-phosphate 3-epimerase FUT79_10315 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) FUT79_10320 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_10325 ENOG4105E2D ec 3.2.1.52 FUT79_10330 ENOG4105DZ1 carboxypeptidase FUT79_10340 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT79_10400 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT79_10405 ENOG4105DRS transport system, permease FUT79_10410 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT79_10440 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT79_10445 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FUT79_10455 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FUT79_10470 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FUT79_10480 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FUT79_10490 ENOG410805Y Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FUT79_10500 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FUT79_10505 ENOG4107QJQ Mate efflux family protein FUT79_10510 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT79_10515 ENOG410691R Modulates RecA activity (By similarity) FUT79_10520 ENOG4108UJD 30S ribosomal protein S9 FUT79_10525 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FUT79_10535 ENOG4108JQ7 (ABC) transporter FUT79_10545 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT79_10550 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT79_10555 ENOG4107QSI ABC, transporter FUT79_10560 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT79_10565 ENOG410841Q phosphoesterase PA-phosphatase related protein FUT79_10580 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FUT79_10585 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FUT79_10590 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT79_10595 ENOG4105YFD chemotaxis, protein FUT79_10610 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_10630 ENOG4105EMN RNA polymerase sigma factor FUT79_10645 ENOG4105EHZ conserved protein UCP016719 FUT79_10655 ENOG4105CZN Potassium uptake protein FUT79_10660 ENOG4107ZYR domain protein FUT79_10675 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT79_10690 ENOG4105WN5 stage II sporulation protein FUT79_10710 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FUT79_10715 ENOG4105BZ1 (ABC) transporter FUT79_10720 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FUT79_10725 ENOG4105C7B Threonine dehydratase FUT79_10730 ENOG4105C28 cystathionine FUT79_10735 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT79_10740 ENOG4105C84 Histidine ammonia-lyase FUT79_10745 ENOG4105C94 Transporter FUT79_10755 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT79_10765 ENOG4105CKB glycosidase FUT79_10785 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FUT79_10795 ENOG4105CEM UPF0597 protein FUT79_10805 ENOG4108KP7 hydrolase FUT79_10810 ENOG4105T73 FUT79_10815 ENOG4105C8J )-transporter FUT79_10820 ENOG4105C4R Atp-dependent dna helicase FUT79_10825 ENOG4105TQV FUT79_10850 ENOG41082I4 UPF0102 protein FUT79_10855 ENOG4105CPI Metal Dependent Phosphohydrolase FUT79_10860 ENOG4105D00 flagellar biosynthetic protein flhB FUT79_10870 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FUT79_10875 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FUT79_10880 ENOG4107GQ3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FUT79_10885 ENOG4105VB6 UPF0109 protein FUT79_10890 ENOG4105K5M 30s ribosomal protein S16 FUT79_10930 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FUT79_10935 ENOG41067SE Tetr family transcriptional regulator FUT79_10945 ENOG4105BZ1 (ABC) transporter FUT79_10955 ENOG4105CBX hi0933 family FUT79_10960 ENOG4107EFR Flavocytochrome c FUT79_10965 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FUT79_10970 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FUT79_10985 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FUT79_11025 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT79_11035 ENOG4105UIB (ABC) transporter FUT79_11040 ENOG4108JQ9 ABC transporter FUT79_11045 ENOG4107TFB basic membrane FUT79_11055 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT79_11060 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT79_11070 ENOG41073FS FUT79_11080 ENOG4108RCM Nitroreductase FUT79_11090 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_11125 ENOG4105D7A ATP-binding protein FUT79_11140 ENOG4106UV5 membrane protein A FUT79_11150 ENOG4105CFP Peptidase U32 FUT79_11155 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FUT79_11160 ENOG4107Z25 Basic membrane protein FUT79_11165 ENOG4105M7K Involved in the transcription termination process (By similarity) FUT79_11185 ENOG4105BZA Phosphoglycerate kinase FUT79_11190 ENOG4105CP7 Triose-phosphate isomerase FUT79_11200 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) FUT79_11205 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FUT79_11230 ENOG4105VUF Transcriptional regulator FUT79_11260 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FUT79_11265 ENOG4105D6U Sodium Glutamate Symporter FUT79_11275 ENOG4105D29 Helix-turn-helix type 11 domain protein FUT79_11380 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_11395 ENOG4105BZ1 (ABC) transporter FUT79_11465 ENOG4105WH1 Two component transcriptional regulator luxr family FUT79_11470 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT79_11490 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT79_11500 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT79_11520 ENOG4107V28 uracil phosphoribosyltransferase FUT79_11530 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT79_11535 ENOG4107SJN Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FUT79_11540 ENOG4105K4W Could be involved in septation (By similarity) FUT79_11550 ENOG4107TVT This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FUT79_11555 ENOG4107THF Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FUT79_11560 ENOG41069X2 FUT79_11570 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FUT79_11590 ENOG4105CM4 permease protein FUT79_11595 ENOG4108IPW abc transporter atp-binding protein FUT79_11600 ENOG4107QKZ Ompa motb domain protein FUT79_11615 ENOG4108NF7 phage-type endonuclease FUT79_11635 ENOG4108PNI recT protein FUT79_11660 ENOG4105Z8H single-stranded DNA-binding protein FUT79_11895 ENOG4107W93 Dihydroorotate dehydrogenase FUT79_11900 ENOG4107XPQ Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FUT79_11910 ENOG4105DVT helicase FUT79_11915 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FUT79_11920 ENOG4105DC7 peptidase M24 FUT79_11930 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT79_11935 ENOG4105G3C Type iv pilus assembly FUT79_11965 ENOG4105DVC DnaJ domain protein FUT79_11970 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FUT79_11985 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) FUT79_12005 ENOG4105CV1 Transketolase (EC 2.2.1.1) FUT79_12020 ENOG4106TP1 FUT79_12035 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FUT79_12045 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT79_12050 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit FUT79_12055 ENOG4105DGN Electron transport complex FUT79_12060 ENOG4105DZB Electron transport complex FUT79_12070 ENOG4105D6A Electron transport complex FUT79_12075 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) FUT79_12095 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT79_12105 ENOG4105HHA aminodeoxychorismate lyase FUT79_12110 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FUT79_12115 ENOG4107QVY Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT79_12135 ENOG4105DFF Rod shape-determining protein mreb FUT79_12150 ENOG4105CJN penicillin-binding protein FUT79_12155 ENOG4105CNI cell division protein FtsW FUT79_12160 ENOG4105EIB trna rrna methyltransferase FUT79_12170 ENOG4105C3J Cysteine desulfurase FUT79_12185 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FUT79_12190 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT79_12195 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FUT79_12200 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_12205 ENOG4105E0C molybdate abc transporter FUT79_12210 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FUT79_12220 ENOG4108RIR Molybdenum cofactor biosynthesis protein FUT79_12235 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FUT79_12240 ENOG4105CEV competence damage-inducible protein FUT79_12245 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT79_12250 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FUT79_12260 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FUT79_12265 ENOG4105BZ8 glutamate synthase FUT79_12270 ENOG4107RCH Diaminopropionate ammonia-lyase FUT79_12275 ENOG4107S4Y M20 DapE family protein YgeY FUT79_12280 ENOG4105IW6 Carbamoyltransferase FUT79_12300 ENOG410908R Methenyltetrahydrofolate cyclohydrolase FUT79_12305 ENOG4105CKU formyltetrahydrofolate synthetase FUT79_12310 ENOG4105CCS Glutamate formiminotransferase FUT79_12315 ENOG4105C84 Histidine ammonia-lyase FUT79_12320 ENOG4105D3Y Na H antiporter FUT79_12330 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FUT79_12335 ENOG4105EEI dihydropteroate synthase FUT79_12340 ENOG4105C8B TIGR00159 family FUT79_12350 ENOG41083V3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FUT79_12355 ENOG4108CER Uncharacterized protein conserved in bacteria (DUF2225) FUT79_12360 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FUT79_12365 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT79_12375 ENOG4105CYC Transferase FUT79_12380 ENOG4105E39 Enoyl-CoA hydratase FUT79_12385 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FUT79_12390 ENOG4105CNW domain protein FUT79_12395 ENOG4105C1G acyl-Coa dehydrogenase FUT79_12400 ENOG4105CHU acetyl-coa acetyltransferase FUT79_12410 ENOG4105C5Y PTS System FUT79_12415 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FUT79_12420 ENOG4105CGK Exodeoxyribonuclease III FUT79_12430 ENOG4105VEM Conserved domain protein FUT79_12435 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT79_12440 ENOG4108JJ8 (ABC) transporter FUT79_12445 ENOG4108JJ9 ABC, transporter FUT79_12450 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FUT79_12455 ENOG4105C4M (Ubiquinol oxidase) subunit I FUT79_12480 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FUT79_12530 ENOG4108Y51 tRNA-binding protein FUT79_12535 ENOG4105CJR Integral membrane protein (MviN FUT79_12555 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FUT79_12560 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FUT79_12570 ENOG4105CUT histidyl-tRNA synthetase FUT79_12575 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FUT79_12580 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FUT79_12595 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FUT79_12615 ENOG4106RHC FUT79_12620 ENOG4108PJD permease FUT79_12630 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FUT79_12660 ENOG4108IUZ ABC transporter FUT79_12665 ENOG4105BZ1 (ABC) transporter FUT79_12670 ENOG4108JJ9 ABC, transporter FUT79_12680 ENOG4106N3A copper homeostasis protein cutc FUT79_12685 ENOG4105CHJ isochorismatase hydrolase FUT79_12755 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT79_12800 ENOG4106TEA FUT79_12835 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FUT79_12840 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FUT79_12855 ENOG4105DFM M18 family aminopeptidase FUT79_12865 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FUT79_12870 ENOG4107I03 FUT79_12895 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FUT79_12910 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_12930 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FUT79_12940 ENOG4108UQV Membrane FUT79_12955 ENOG4105CAH Chromate FUT79_12975 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT79_12980 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) FUT79_12990 ENOG4105C26 Dehydrogenase FUT79_13000 ENOG4108JQ1 Dehydrogenase FUT79_13025 ENOG4105K95 (LipO)protein FUT79_13040 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FUT79_13045 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) FUT79_13050 ENOG4106AHS FUT79_13055 ENOG4107QIV Cytochrome c biogenesis protein FUT79_13060 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT79_13075 ENOG4105F2I Transposase FUT79_13090 ENOG4105KZ7 phosphocarrier protein hpr FUT79_13095 ENOG4105DM4 PTS System FUT79_13100 ENOG4105DE4 1-phosphofructokinase FUT79_13105 ENOG4105E98 transcriptional regulator DeoR family FUT79_13110 ENOG4105D3R alkyl hydroperoxide reductase FUT79_13130 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT79_13135 ENOG4105C3M thioredoxin reductase FUT79_13155 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT79_13165 ENOG4108JQ7 (ABC) transporter FUT79_13175 ENOG4105BZ1 (ABC) transporter FUT79_13180 ENOG4105BZ1 (ABC) transporter FUT79_13185 ENOG4105BZ1 (ABC) transporter FUT79_13190 ENOG4105BZ1 (ABC) transporter FUT79_13200 ENOG4105CPF Cell wall formation (By similarity) FUT79_13210 ENOG4107TIA phenylalanyl-tRNA synthetase (beta subunit) FUT79_13235 ENOG4105D7X high-affinity nickel-transporter FUT79_13250 ENOG4105DQ6 Transposase FUT79_13275 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FUT79_13280 ENOG4108IUS Transketolase FUT79_13285 ENOG4108HHA Transketolase FUT79_13305 ENOG4108JJB ABC transporter FUT79_13310 ENOG4105VKD bioY protein FUT79_13315 ENOG4105C3G gtp-binding protein FUT79_13320 ENOG4105CTQ phosphohexokinase FUT79_13330 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_13350 ENOG4105CJ2 (LipO)protein FUT79_13405 ENOG410600T transposase FUT79_13530 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT79_13650 ENOG4107YVC modification (methylase) FUT79_13695 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) FUT79_13710 ENOG4105ES4 Nitrilase FUT79_13725 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FUT79_13785 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FUT79_13800 ENOG4105D5T phosphonate abc transporter FUT79_13815 ENOG4106PMH Extracellular solute-binding protein family 3 FUT79_13875 ENOG4105CMT Dihydroxyacetone kinase FUT79_13915 ENOG4108JJB ABC transporter FUT79_13935 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT79_13955 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT79_13960 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FUT79_13995 ENOG4105NBF ammecr1 domain protein FUT79_14000 ENOG4108IQE Amp-dependent synthetase and ligase FUT79_14020 ENOG4105RJI FUT79_14025 ENOG410877G FUT79_14030 ENOG4108TVT permease FUT79_14040 ENOG4105CDY transcriptional regulatory protein FUT79_14050 ENOG4105CXB phosphoribosylaminoimidazole synthetase FUT79_14055 ENOG4108V3E phosphoribosylglycinamide formyltransferase FUT79_14060 ENOG4105C8Q Methyl-accepting chemotaxis FUT79_14075 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_14080 ENOG4107RCV ABC transporter, permease FUT79_14085 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT79_14090 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FUT79_14095 ENOG4105CUZ uba thif-type nad fad binding protein FUT79_14155 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT79_14185 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FUT79_14210 ENOG4105C2M dna polymerase I FUT79_14220 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FUT79_14230 ENOG4105FB2 class II Aldolase FUT79_14240 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FUT79_14245 ENOG4105E98 transcriptional regulator DeoR family FUT79_14250 ENOG4105CTS PTS system mannitol-specific FUT79_14255 ENOG4105E0Y RtcB Protein FUT79_14260 ENOG4105DPN Oligoendopeptidase f FUT79_14275 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT79_14285 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FUT79_14310 ENOG410822I Flagellar hook capping protein FUT79_14315 ENOG4105BZE flagellar hook protein, FlgE FUT79_14325 ENOG4107R0U MotA TolQ exbB proton channel FUT79_14330 ENOG4107XSU flagellar motor protein motb FUT79_14335 ENOG41064SM flagellar basal body-associated protein flil FUT79_14340 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT79_14345 ENOG4105DD5 Flagellar motor switch protein FUT79_14355 ENOG4105CN7 Flagellar biosynthetic protein FliP FUT79_14360 ENOG4105VS8 Flagellar biosynthetic protein fliq FUT79_14365 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FUT79_14370 ENOG4105D00 flagellar biosynthetic protein flhB FUT79_14375 ENOG4105D7B Flagellar biosynthesis protein flha FUT79_14380 ENOG4105FZW flagellar biosynthesis regulator FlhF FUT79_14390 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT79_14395 ENOG41082MQ UPF0178 protein FUT79_14400 ENOG4105EIP mannose-6-phosphate isomerase FUT79_14405 ENOG4106BMT Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) FUT79_14410 ENOG4106BH8 FUT79_14415 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FUT79_14420 ENOG41084MZ 50S ribosomal protein L35 FUT79_14425 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FUT79_14430 ENOG4105C0H protease FUT79_14435 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT79_14450 ENOG41083NY Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FUT79_14455 ENOG4105E66 phosphoriboisomerase A FUT79_14460 ENOG4107YNV 3-dehydroquinate dehydratase FUT79_14475 ENOG4105DAP Nicotinate phosphoribosyltransferase FUT79_14485 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FUT79_14495 ENOG4105DR5 peptidase FUT79_14510 ENOG4105MA4 psp1 domain protein FUT79_14515 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FUT79_14540 ENOG4105DCI Phosphohydrolase FUT79_14545 ENOG4105MAX Superoxide reductase FUT79_14550 ENOG4108I7Y domain protein FUT79_14560 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FUT79_14565 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FUT79_14570 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FUT79_14575 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FUT79_14580 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FUT79_14585 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FUT79_14590 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FUT79_14595 ENOG41082G4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FUT79_14600 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FUT79_14605 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FUT79_14610 ENOG41086S0 50s ribosomal protein l29 FUT79_14615 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FUT79_14620 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FUT79_14625 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FUT79_14630 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FUT79_14635 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FUT79_14640 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FUT79_14645 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FUT79_14650 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FUT79_14655 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FUT79_14660 ENOG41084HK 50S ribosomal protein L30 FUT79_14665 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FUT79_14670 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FUT79_14675 ENOG41067V7 50S ribosomal protein L36 FUT79_14680 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FUT79_14685 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FUT79_14690 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT79_14695 ENOG4108ZT0 50S ribosomal protein l17 FUT79_14700 ENOG4106DC9 FUT79_14725 ENOG4109015 Biopolymer transport protein exbD tolR FUT79_14735 ENOG4105E6M Sulphatase-modifying factor protein FUT79_14750 ENOG4105D4B ABC, transporter FUT79_14755 ENOG4105C2J ABC transporter FUT79_14760 ENOG4105CNN ABC, transporter FUT79_14765 ENOG4105CNN ABC, transporter FUT79_14805 ENOG4105DIW FeS assembly protein SUFB FUT79_14815 ENOG4105C9B Cysteine desulfurase FUT79_14820 ENOG4107YH3 SUF system FeS assembly protein, NifU family FUT79_14830 ENOG41088SP formiminoglutamate hydrolase FUT79_14840 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FUT79_14845 ENOG4105HFZ Membrane FUT79_14855 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FUT79_14865 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FUT79_14875 ENOG4108JJB ABC transporter FUT79_14880 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FUT79_14885 ENOG4108IG5 Transcriptional regulator FUT79_14890 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FUT79_14900 ENOG4108UVJ appr-1-p processing domain protein FUT79_14915 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FUT79_14920 ENOG4108UMN azlc family FUT79_14925 ENOG4105KMT branched-chain amino acid