locus-tag	class	description
DWQ65_00015	COG0826	peptidase U32
DWQ65_00020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DWQ65_00025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DWQ65_00050	COG0126	phosphoglycerate kinase activity
DWQ65_00055	COG0149	triose-phosphate isomerase activity
DWQ65_00075	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DWQ65_00080	COG0588	phosphoglycerate mutase activity
DWQ65_00105	COG0789	Transcriptional regulator
DWQ65_00130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DWQ65_00135	COG0786	glutamate:sodium symporter activity
DWQ65_00155	COG2197	response regulator
DWQ65_00160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DWQ65_00180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DWQ65_00190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DWQ65_00215	COG0167	dihydroorotate dehydrogenase activity
DWQ65_00230	COG1199	ATP-dependent helicase activity
DWQ65_00235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DWQ65_00245	COG2211	Major facilitator Superfamily
DWQ65_00250	COG3064	Membrane
DWQ65_00265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DWQ65_00270	COG0840	transmembrane signaling receptor activity
DWQ65_00285	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DWQ65_00300	COG0024	Methionine aminopeptidase
DWQ65_00305	COG0484	heat shock protein binding
DWQ65_00345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DWQ65_00355	COG0006	proline dipeptidase activity
DWQ65_00360	COG1598	PFAM Uncharacterised protein family UPF0150
DWQ65_00370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DWQ65_00375	COG1245	4Fe-4S binding domain
DWQ65_00375	COG2878	Part of a membrane complex involved in electron transport
DWQ65_00380	COG4657	Part of a membrane complex involved in electron transport
DWQ65_00385	COG4660	Part of a membrane complex involved in electron transport
DWQ65_00395	COG4658	electron transport chain
DWQ65_00400	COG4656	Part of a membrane complex involved in electron transport
DWQ65_00420	COG1234	tRNA 3'-trailer cleavage
DWQ65_00430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DWQ65_00435	COG0358	DNA primase activity
DWQ65_00440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DWQ65_00460	COG1077	Cell shape determining protein MreB Mrl
DWQ65_00475	COG0768	penicillin binding
DWQ65_00480	COG0772	Belongs to the SEDS family
DWQ65_00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DWQ65_00495	COG1104	cysteine desulfurase activity
DWQ65_00510	COG0709	Synthesizes selenophosphate from selenide and ATP
DWQ65_00515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DWQ65_00515	COG3608	succinylglutamate desuccinylase aspartoacylase
DWQ65_00520	COG0746	molybdenum cofactor guanylyltransferase activity
DWQ65_00525	COG3842	ATPase activity
DWQ65_00530	COG4149	molybdate abc transporter
DWQ65_00535	COG0725	ABC transporter, periplasmic molybdate-binding protein
DWQ65_00545	COG0521	Mo-molybdopterin cofactor biosynthetic process
DWQ65_00560	COG0315	cyclic pyranopterin monophosphate synthase activity
DWQ65_00565	COG1546	Belongs to the CinA family
DWQ65_00565	COG1058	Belongs to the CinA family
DWQ65_00570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DWQ65_00570	COG3608	succinylglutamate desuccinylase aspartoacylase
DWQ65_00575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DWQ65_00590	COG0402	S-adenosylhomocysteine deaminase activity
DWQ65_00595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DWQ65_00595	COG0493	'glutamate synthase
DWQ65_00605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DWQ65_00610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DWQ65_00630	COG3404	Formiminotransferase-cyclodeaminase
DWQ65_00645	COG2986	histidine ammonia-lyase
DWQ65_00650	COG2056	Na+-H+ antiporter family
DWQ65_00655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DWQ65_00660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DWQ65_00665	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DWQ65_00685	COG0101	tRNA pseudouridine synthase activity
DWQ65_00690	COG0297	glycogen (starch) synthase activity
DWQ65_00705	COG0427	acetyl-CoA hydrolase
DWQ65_00710	COG1024	Enoyl-CoA hydratase
DWQ65_00715	COG1250	3-hydroxyacyl-CoA dehydrogenase
DWQ65_00720	COG0426	domain, Protein
DWQ65_00725	COG1960	acyl-CoA dehydrogenase activity
DWQ65_00730	COG0183	Belongs to the thiolase family
DWQ65_00750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DWQ65_00755	COG2890	protein-(glutamine-N5) methyltransferase activity
DWQ65_00760	COG1022	Amp-dependent synthetase and ligase
DWQ65_00770	COG1321	iron dependent repressor
DWQ65_00775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWQ65_00780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWQ65_00785	COG1121	(ABC) transporter
DWQ65_00790	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWQ65_00800	COG1028	Short-chain dehydrogenase reductase Sdr
DWQ65_00815	COG0154	amidase activity
DWQ65_00820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DWQ65_00825	COG0124	histidyl-tRNA synthetase
DWQ65_00835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DWQ65_00840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DWQ65_00845	COG0579	oxidoreductase
DWQ65_00860	COG0728	peptidoglycan biosynthetic process
DWQ65_00865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWQ65_00945	COG1271	oxidase subunit
DWQ65_00950	COG1294	oxidase, subunit
DWQ65_00955	COG4988	ABC transporter
DWQ65_00960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DWQ65_00965	COG0328	RNA-DNA hybrid ribonuclease activity
DWQ65_00970	COG4443	Transcriptional Coactivator p15 (PC4)
DWQ65_00980	COG0708	Exodeoxyribonuclease III
DWQ65_00985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DWQ65_00990	COG1263	PTS System
DWQ65_00990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWQ65_01015	COG0658	competence protein
DWQ65_01015	COG2333	competence protein COMEC
DWQ65_01040	COG0285	dihydrofolate synthase activity
DWQ65_01045	COG2832	Protein of unknown function (DUF454)
DWQ65_01050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DWQ65_01060	COG1269	ATP hydrolysis coupled proton transport
DWQ65_01065	COG1394	ATPase activity, coupled to movement of substances
DWQ65_01070	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DWQ65_01075	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DWQ65_01085	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DWQ65_01115	COG1983	PspC domain protein
DWQ65_01145	COG1136	(ABC) transporter
DWQ65_01155	COG1136	(ABC) transporter
DWQ65_01155	COG0577	efflux transmembrane transporter activity
DWQ65_01170	COG4475	Protein of unknown function (DUF436)
DWQ65_01175	COG4475	Protein of unknown function (DUF436)
DWQ65_01180	COG2252	PERMEase
DWQ65_01200	COG0395	ABC-type sugar transport system, permease component
DWQ65_01210	COG4209	transmembrane transport
DWQ65_01220	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DWQ65_01225	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DWQ65_01235	COG0786	glutamate:sodium symporter activity
DWQ65_01240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DWQ65_01245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DWQ65_01250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DWQ65_01255	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DWQ65_01260	COG4770	biotin carboxylase activity
DWQ65_01270	COG0786	glutamate:sodium symporter activity
DWQ65_01275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DWQ65_01290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DWQ65_01305	COG1744	ABC transporter substrate-binding protein PnrA-like
DWQ65_01310	COG3845	ABC transporter
DWQ65_01315	COG4603	Belongs to the binding-protein-dependent transport system permease family
DWQ65_01320	COG1079	Belongs to the binding-protein-dependent transport system permease family
DWQ65_01330	COG1346	cytolysis
DWQ65_01355	COG0191	fructose-bisphosphate aldolase activity
DWQ65_01380	COG4166	transmembrane transport
DWQ65_01395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWQ65_01415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWQ65_01420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DWQ65_01425	COG1862	Preprotein translocase
DWQ65_01430	COG1639	'signal transduction protein
DWQ65_01440	COG4115	mRNA cleavage
DWQ65_01445	COG2801	Transposase and inactivated derivatives
DWQ65_01450	COG2801	Transposase and inactivated derivatives
DWQ65_01460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DWQ65_01470	COG0504	CTP synthase activity
DWQ65_01475	COG1757	Na H antiporter
DWQ65_01490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DWQ65_01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWQ65_01505	COG0765	amino acid transport
DWQ65_01510	COG1126	abc transporter atp-binding protein
DWQ65_01525	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DWQ65_01535	COG1175	transmembrane transport
DWQ65_01545	COG0330	HflC and HflK could
DWQ65_01550	COG0330	HflC and HflK could
DWQ65_01570	COG1785	Belongs to the alkaline phosphatase family
DWQ65_01595	COG1136	(ABC) transporter
DWQ65_01615	COG1132	(ABC) transporter
DWQ65_01620	COG1132	(ABC) transporter
DWQ65_01640	COG0525	valine-tRNA ligase activity
DWQ65_01655	COG0737	Belongs to the 5'-nucleotidase family
DWQ65_01665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DWQ65_01670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DWQ65_01680	COG3437	response regulator, receiver
DWQ65_01685	COG1671	Belongs to the UPF0178 family
DWQ65_01695	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DWQ65_01705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DWQ65_01720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWQ65_01725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DWQ65_01740	COG0237	dephospho-CoA kinase activity
DWQ65_01745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DWQ65_01750	COG0710	3-dehydroquinate dehydratase activity
DWQ65_01750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DWQ65_01765	COG2095	MarC family integral membrane protein
DWQ65_01775	COG2801	Transposase and inactivated derivatives
DWQ65_01780	COG2801	Transposase and inactivated derivatives
DWQ65_01810	COG1070	Carbohydrate kinase
DWQ65_01820	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DWQ65_01825	COG1739	Uncharacterized protein family UPF0029
DWQ65_01840	COG0756	dUTP diphosphatase activity
DWQ65_01845	COG1185	polyribonucleotide nucleotidyltransferase activity
DWQ65_01855	COG0196	riboflavin kinase activity
DWQ65_01865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DWQ65_01875	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DWQ65_01885	COG0779	Required for maturation of 30S ribosomal subunits
DWQ65_01895	COG0343	queuine tRNA-ribosyltransferase activity
DWQ65_01905	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DWQ65_01935	COG1368	sulfuric ester hydrolase activity
DWQ65_01940	COG1368	sulfuric ester hydrolase activity
DWQ65_01960	COG1802	Transcriptional regulator
DWQ65_01975	COG0656	L-ascorbic acid biosynthetic process
DWQ65_01985	COG3842	ATPase activity
DWQ65_01990	COG0737	Belongs to the 5'-nucleotidase family
DWQ65_02015	COG1067	ATP-dependent peptidase activity
DWQ65_02055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWQ65_02055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DWQ65_02070	COG1104	cysteine desulfurase activity
DWQ65_02075	COG0778	Nitroreductase
DWQ65_02090	COG2801	Transposase and inactivated derivatives
DWQ65_02115	COG0733	neurotransmitter:sodium symporter activity
DWQ65_02120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DWQ65_02130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DWQ65_02150	COG2116	formate transmembrane transporter activity
DWQ65_02155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DWQ65_02175	COG3385	transposase activity
DWQ65_02235	COG0629	single-stranded DNA binding
DWQ65_02490	COG2339	peptidase activity
DWQ65_02495	COG0151	Belongs to the GarS family
DWQ65_02500	COG0138	bifunctional purine biosynthesis protein purh
DWQ65_02520	COG1509	lysine 2,3-aminomutase activity
DWQ65_02525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DWQ65_02535	COG1177	transmembrane transport
DWQ65_02540	COG1176	ABC-type spermidine putrescine transport system, permease component I
DWQ65_02545	COG3842	ATPase activity
DWQ65_02550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWQ65_02560	COG0724	RNA recognition motif
DWQ65_02570	COG1979	alcohol dehydrogenase
DWQ65_02580	COG1388	LysM domain
DWQ65_02580	COG0791	NLP P60 protein
DWQ65_02585	COG0318	PFAM AMP-dependent synthetase and ligase
DWQ65_02595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DWQ65_02595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DWQ65_02600	COG0739	heme binding
DWQ65_02610	COG0295	cytidine deaminase activity
DWQ65_02620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWQ65_02640	COG1272	protein, Hemolysin III
DWQ65_02680	COG2239	Acts as a magnesium transporter
DWQ65_02685	COG0460	homoserine dehydrogenase
DWQ65_02690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DWQ65_02695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DWQ65_02710	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DWQ65_02725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DWQ65_02730	COG4608	Belongs to the ABC transporter superfamily
DWQ65_02735	COG0444	Belongs to the ABC transporter superfamily
DWQ65_02745	COG0601	transmembrane transport
DWQ65_02755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWQ65_02760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DWQ65_02760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DWQ65_02775	COG0523	cobalamin synthesis protein
DWQ65_02785	COG1349	DNA-binding transcription factor activity
DWQ65_02795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWQ65_02800	COG0191	fructose-bisphosphate aldolase activity
DWQ65_02805	COG0673	inositol 2-dehydrogenase activity
DWQ65_02810	COG1228	amidohydrolase
DWQ65_02845	COG0432	Pfam Uncharacterised protein family UPF0047
DWQ65_02855	COG0513	Belongs to the DEAD box helicase family
DWQ65_02875	COG1131	(ABC) transporter
DWQ65_02885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DWQ65_02905	COG1129	ABC transporter
DWQ65_02910	COG1172	Belongs to the binding-protein-dependent transport system permease family
DWQ65_02920	COG0626	cystathionine gamma-synthase activity
DWQ65_02930	COG1175	transmembrane transport
DWQ65_02945	COG0617	tRNA 3'-terminal CCA addition
DWQ65_02960	COG0433	COG0433 Predicted ATPase
DWQ65_02995	COG3039	Transposase
DWQ65_03035	COG0840	transmembrane signaling receptor activity
DWQ65_03045	COG0778	Nitroreductase
DWQ65_03085	COG1744	ABC transporter substrate-binding protein PnrA-like
DWQ65_03090	COG3845	ABC transporter
DWQ65_03095	COG4603	Belongs to the binding-protein-dependent transport system permease family
DWQ65_03100	COG1079	Belongs to the binding-protein-dependent transport system permease family
DWQ65_03105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DWQ65_03205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DWQ65_03645	COG0716	FMN binding
DWQ65_03655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DWQ65_03665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DWQ65_03670	COG0250	Participates in transcription elongation, termination and antitermination
DWQ65_03675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DWQ65_03680	COG0081	regulation of translation
DWQ65_03695	COG0085	RNA polymerase activity
DWQ65_03705	COG1394	ATPase activity, coupled to movement of substances
DWQ65_03720	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DWQ65_03730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DWQ65_03730	COG0426	domain, Protein
DWQ65_03735	COG2304	oxidoreductase activity
DWQ65_03750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWQ65_03750	COG0574	Belongs to the PEP-utilizing enzyme family
DWQ65_03760	COG1131	(ABC) transporter
DWQ65_03770	COG0180	Tryptophanyl-tRNA synthetase
DWQ65_03775	COG3735	TraB family
DWQ65_03780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DWQ65_03785	COG1187	pseudouridine synthase activity
DWQ65_03795	COG3700	Belongs to the class B bacterial acid phosphatase family
DWQ65_03800	COG0571	ribonuclease III activity
DWQ65_03805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DWQ65_03810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DWQ65_03820	COG0563	adenylate kinase activity
DWQ65_03885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DWQ65_03930	COG0531	amino acid
DWQ65_03945	COG0740	serine-type endopeptidase activity
DWQ65_03950	COG0543	2 iron, 2 sulfur cluster binding
DWQ65_03955	COG0493	'glutamate synthase
DWQ65_03975	COG2197	response regulator
DWQ65_04050	COG3385	transposase activity
DWQ65_04095	COG2226	methyltransferase
DWQ65_04100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DWQ65_04110	COG2195	Cleaves the N-terminal amino acid of tripeptides
DWQ65_04115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DWQ65_04120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DWQ65_04120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DWQ65_04125	COG0739	heme binding
DWQ65_04140	COG1132	(ABC) transporter
DWQ65_04145	COG1132	(ABC) transporter
DWQ65_04155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DWQ65_04165	COG1187	pseudouridine synthase activity
DWQ65_04200	COG1132	(ABC) transporter
DWQ65_04205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DWQ65_04225	COG3706	GGDEF domain
DWQ65_04240	COG1413	lyase activity
DWQ65_04250	COG1012	belongs to the aldehyde dehydrogenase family
DWQ65_04255	COG0673	inositol 2-dehydrogenase activity
DWQ65_04260	COG1172	Belongs to the binding-protein-dependent transport system permease family
DWQ65_04270	COG1879	ABC-type sugar transport system periplasmic component
DWQ65_04310	COG2610	gluconate transmembrane transporter activity
DWQ65_04315	COG1929	Belongs to the glycerate kinase type-1 family
DWQ65_04325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DWQ65_04330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DWQ65_04345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DWQ65_04405	COG0110	maltose O-acetyltransferase activity
DWQ65_04420	COG3579	cysteine-type endopeptidase activity
DWQ65_04440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DWQ65_04460	COG2770	Histidine kinase
DWQ65_04460	COG3437	response regulator, receiver
DWQ65_04465	COG1214	PFAM Peptidase M22, glycoprotease
DWQ65_04470	COG0802	atpase or kinase
DWQ65_04475	COG0322	excinuclease ABC activity
DWQ65_04505	COG2885	chlorophyll binding
DWQ65_04520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DWQ65_04525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DWQ65_04535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DWQ65_04535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DWQ65_04560	COG0564	pseudouridine synthase activity
DWQ65_04570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DWQ65_04580	COG0488	(ABC) transporter
DWQ65_04580	COG0488	(ABC) transporter
DWQ65_04590	COG1573	uracil-dna glycosylase
DWQ65_04595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DWQ65_04600	COG1086	Polysaccharide biosynthesis protein
DWQ65_04615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DWQ65_04625	COG2801	Transposase and inactivated derivatives
DWQ65_04630	COG2801	Transposase and inactivated derivatives
DWQ65_04640	COG0017	Asparaginyl-tRNA synthetase
DWQ65_04645	COG0840	transmembrane signaling receptor activity
DWQ65_04655	COG3630	sodium ion export across plasma membrane
DWQ65_04660	COG0511	ligase activity, forming carbon-carbon bonds
DWQ65_04660	COG5016	pyruvate
DWQ65_04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWQ65_04675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DWQ65_04685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DWQ65_04690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DWQ65_04700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DWQ65_04705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DWQ65_04710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DWQ65_04780	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DWQ65_04790	COG2233	PERMEase
DWQ65_04800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DWQ65_04805	COG3177	Filamentation induced by cAMP protein fic
DWQ65_04825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DWQ65_04845	COG0542	response to heat
DWQ65_04855	COG0457	Tetratricopeptide repeat
DWQ65_04860	COG1475	DNA binding
DWQ65_04865	COG1438	arginine binding
DWQ65_04870	COG0251	oxidation-reduction process
DWQ65_04905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DWQ65_04925	COG3475	LICD family
DWQ65_04960	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DWQ65_04960	COG0028	Belongs to the TPP enzyme family
DWQ65_05015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DWQ65_05030	COG1178	ABC-type Fe3 transport system permease component
DWQ65_05035	COG3842	ATPase activity
DWQ65_05070	COG5002	protein histidine kinase activity
DWQ65_05070	COG5001	Diguanylate cyclase
DWQ65_05075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DWQ65_05075	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DWQ65_05085	COG3118	belongs to the thioredoxin family
DWQ65_05090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DWQ65_05100	COG1516	flagellar protein fliS
DWQ65_05120	COG4209	transmembrane transport
DWQ65_05125	COG1040	competence protein
DWQ65_05140	COG1388	LysM domain
DWQ65_05140	COG0741	lytic transglycosylase activity
DWQ65_05150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DWQ65_05160	COG1475	DNA binding
DWQ65_05165	COG1192	Involved in chromosome partitioning
DWQ65_05170	COG4953	penicillin-binding protein 1C
DWQ65_05175	COG2373	Large extracellular alpha-helical protein
DWQ65_05180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DWQ65_05195	COG2089	acid synthase
DWQ65_05205	COG0495	leucyl-tRNA aminoacylation
DWQ65_05210	COG0351	phosphomethylpyrimidine kinase
DWQ65_05220	COG0739	heme binding
DWQ65_05230	COG0739	heme binding
DWQ65_05255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DWQ65_05260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DWQ65_05265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DWQ65_05280	COG1227	inorganic diphosphatase activity
DWQ65_05280	COG0517	IMP dehydrogenase activity
DWQ65_05290	COG0768	penicillin binding
DWQ65_05295	COG2604	Protein of unknown function DUF115
DWQ65_05330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DWQ65_05335	COG1760	l-serine dehydratase
DWQ65_05340	COG1760	l-serine dehydratase
DWQ65_05345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWQ65_05345	COG0574	Belongs to the PEP-utilizing enzyme family
DWQ65_05365	COG1592	Rubrerythrin
DWQ65_05375	COG2604	Protein of unknown function DUF115
DWQ65_05380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DWQ65_05390	COG0803	Belongs to the bacterial solute-binding protein 9 family
DWQ65_05395	COG1121	(ABC) transporter
DWQ65_05400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DWQ65_05405	COG1473	amidohydrolase
DWQ65_05425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DWQ65_05455	COG0552	protein localization to endoplasmic reticulum
DWQ65_05470	COG1136	(ABC) transporter
DWQ65_05485	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DWQ65_05510	COG0049	tRNA binding
DWQ65_05515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DWQ65_05520	COG1053	succinate dehydrogenase
DWQ65_05525	COG2081	HI0933 family
DWQ65_05535	COG0187	DNA topoisomerase II activity
DWQ65_05575	COG0534	Mate efflux family protein
DWQ65_05615	COG1285	pathogenesis
DWQ65_05620	COG3330	Domain of unknown function (DUF4912)
DWQ65_05635	COG0455	bacterial-type flagellum organization
DWQ65_05645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DWQ65_05665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DWQ65_05670	COG0740	serine-type endopeptidase activity
DWQ65_05675	COG0544	peptidyl-prolyl cis-trans isomerase activity
DWQ65_05720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DWQ65_05720	COG3116	cell division
DWQ65_05725	COG0084	hydrolase, TatD family'
DWQ65_05750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DWQ65_05760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DWQ65_05770	COG0360	Binds together with S18 to 16S ribosomal RNA
DWQ65_05775	COG0629	single-stranded DNA binding
DWQ65_05780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DWQ65_05785	COG0359	binds to the 23S rRNA
DWQ65_05790	COG0305	Participates in initiation and elongation during chromosome replication
DWQ65_05830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DWQ65_05835	COG1160	GTP binding
DWQ65_05855	COG2801	Transposase and inactivated derivatives
DWQ65_05865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_05865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_05865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_05890	COG0484	heat shock protein binding
DWQ65_05895	COG0443	Heat shock 70 kDa protein
DWQ65_05900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DWQ65_05905	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DWQ65_05910	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DWQ65_05930	COG1269	ATP hydrolysis coupled proton transport
DWQ65_05935	COG1527	subunit (C
DWQ65_05945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_05945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_05945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_05950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DWQ65_05965	COG2313	pseudouridylate synthase activity
DWQ65_05970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWQ65_05975	COG2001	Belongs to the MraZ family
DWQ65_05980	COG0275	rRNA processing
DWQ65_05990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DWQ65_05995	COG0772	Belongs to the SEDS family
DWQ65_06000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DWQ65_06010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DWQ65_06015	COG4974	Belongs to the 'phage' integrase family
DWQ65_06025	COG0758	DNA mediated transformation
DWQ65_06030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DWQ65_06030	COG0551	DNA topoisomerase type I activity
DWQ65_06035	COG4974	Belongs to the 'phage' integrase family
DWQ65_06040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DWQ65_06045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DWQ65_06055	COG1815	bacterial-type flagellum-dependent cell motility
DWQ65_06070	COG1766	The M ring may be actively involved in energy transduction
DWQ65_06080	COG1317	bacterial-type flagellum organization
DWQ65_06085	COG1157	protein secretion by the type III secretion system
DWQ65_06100	COG0019	diaminopimelate decarboxylase activity
DWQ65_06115	COG0438	transferase activity, transferring glycosyl groups
DWQ65_06145	COG2186	Transcriptional regulator
DWQ65_06155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DWQ65_06170	COG0277	FAD linked oxidase domain protein
DWQ65_06180	COG1490	D-aminoacyl-tRNA deacylase activity
DWQ65_06185	COG0193	aminoacyl-tRNA hydrolase activity
DWQ65_06205	COG1473	amidohydrolase
DWQ65_06220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DWQ65_06230	COG0545	Peptidyl-prolyl cis-trans isomerase
DWQ65_06250	COG2217	Heavy metal translocating P-type atpase
DWQ65_06265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DWQ65_06270	COG0813	purine-nucleoside phosphorylase activity
DWQ65_06275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DWQ65_06285	COG0840	transmembrane signaling receptor activity
DWQ65_06315	COG2801	Transposase and inactivated derivatives
DWQ65_06320	COG0205	6-phosphofructokinase activity
DWQ65_06325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DWQ65_06340	COG0142	geranyltranstransferase activity
DWQ65_06350	COG1692	metallophosphoesterase
DWQ65_06380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DWQ65_06385	COG1286	toxin biosynthetic process
DWQ65_06390	COG0470	DNA polymerase III
DWQ65_06395	COG3852	Histidine kinase
DWQ65_06400	COG2204	response regulator
DWQ65_06450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DWQ65_06450	COG1918	ferrous iron import across plasma membrane
DWQ65_06465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DWQ65_06465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DWQ65_06465	COG1013	pyruvate-flavodoxin oxidoreductase activity
DWQ65_06465	COG0674	pyruvate-flavodoxin oxidoreductase activity
DWQ65_06490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DWQ65_06510	COG1162	GTPase activity
DWQ65_06515	COG1193	negative regulation of DNA recombination
DWQ65_06525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DWQ65_06535	COG3951	Flagellar rod assembly protein muramidase FlgJ
DWQ65_06540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DWQ65_06550	COG1047	Peptidyl-prolyl cis-trans
DWQ65_06560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DWQ65_06570	COG1309	transcriptional regulator
DWQ65_06580	COG0037	tRNA processing
DWQ65_06585	COG1879	ABC-type sugar transport system periplasmic component
DWQ65_06590	COG1692	metallophosphoesterase
DWQ65_06600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DWQ65_06620	COG1115	amino acid carrier protein
DWQ65_06630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DWQ65_06655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DWQ65_06675	COG0530	calcium, potassium:sodium antiporter activity
DWQ65_06695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DWQ65_06695	COG0321	lipoyl(octanoyl) transferase activity
DWQ65_06715	COG2204	response regulator
DWQ65_06720	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DWQ65_06730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DWQ65_06755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DWQ65_06780	COG0405	Gamma-glutamyltransferase
DWQ65_06795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DWQ65_06800	COG0587	DNA-directed DNA polymerase activity
DWQ65_06805	COG0762	integral membrane protein
DWQ65_06810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DWQ65_06815	COG0584	glycerophosphoryl diester phosphodiesterase
DWQ65_06820	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DWQ65_06830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DWQ65_06835	COG0542	response to heat
DWQ65_06865	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DWQ65_06870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DWQ65_06890	COG0826	peptidase U32
DWQ65_06920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DWQ65_06965	COG1366	Belongs to the anti-sigma-factor antagonist family
DWQ65_06980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DWQ65_06990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DWQ65_06995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DWQ65_07025	COG1640	4-alpha-glucanotransferase
DWQ65_07045	COG1136	(ABC) transporter
DWQ65_07055	COG0672	)-iron permease
DWQ65_07060	COG3470	protein probably involved in high-affinity Fe2 transport
DWQ65_07075	COG1136	(ABC) transporter
DWQ65_07075	COG0577	efflux transmembrane transporter activity
DWQ65_07090	COG1136	(ABC) transporter
DWQ65_07110	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DWQ65_07110	COG3976	FMN-binding domain protein
DWQ65_07115	COG2070	2-Nitropropane dioxygenase
DWQ65_07120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DWQ65_07140	COG0739	heme binding
DWQ65_07165	COG0666	response to abiotic stimulus
DWQ65_07200	COG2502	aspartate--ammonia ligase
DWQ65_07210	COG1704	LemA family
DWQ65_07220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DWQ65_07255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DWQ65_07260	COG0301	tRNA thio-modification
DWQ65_07275	COG4786	Flagellar basal body rod
DWQ65_07285	COG2188	Transcriptional regulator
DWQ65_07290	COG1263	PTS System
DWQ65_07290	COG2190	(PTS) system
DWQ65_07290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DWQ65_07295	COG0561	phosphatase activity
DWQ65_07300	COG2723	6-phospho-beta-galactosidase activity
DWQ65_07310	COG0363	glucosamine-6-phosphate deaminase activity
DWQ65_07315	COG0714	Associated with various cellular activities
DWQ65_07325	COG1305	Transglutaminase-like
DWQ65_07330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DWQ65_07345	COG0706	membrane insertase activity
DWQ65_07350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DWQ65_07360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DWQ65_07370	COG1640	4-alpha-glucanotransferase
DWQ65_07375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DWQ65_07385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DWQ65_07390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_07410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DWQ65_07440	COG2932	Transcriptional regulator
DWQ65_07520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DWQ65_07535	COG4211	Belongs to the binding-protein-dependent transport system permease family
DWQ65_07540	COG1129	ABC transporter
DWQ65_07545	COG1879	ABC-type sugar transport system periplasmic component
DWQ65_07555	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DWQ65_07560	COG2088	sporulation resulting in formation of a cellular spore
DWQ65_07570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DWQ65_07575	COG0037	tRNA processing
DWQ65_07580	COG0457	Tetratricopeptide repeat
DWQ65_07585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWQ65_07590	COG0481	GTPase activity
DWQ65_07595	COG0840	transmembrane signaling receptor activity
DWQ65_07610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DWQ65_07690	COG0297	glycogen (starch) synthase activity
DWQ65_07745	COG2738	Putative neutral zinc metallopeptidase
DWQ65_07780	COG2255	four-way junction helicase activity
DWQ65_07785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DWQ65_07795	COG1362	aminopeptidase activity
DWQ65_07805	COG1570	exodeoxyribonuclease VII activity
DWQ65_07830	COG4750	Nucleotidyl transferase
DWQ65_07835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DWQ65_07865	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DWQ65_07870	COG1214	PFAM Peptidase M22, glycoprotease
DWQ65_07870	COG0456	acetyltransferase
DWQ65_07875	COG1811	Na channel or pump
DWQ65_07890	COG2059	Chromate
DWQ65_07915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DWQ65_07920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DWQ65_07930	COG1196	nuclear chromosome segregation
DWQ65_07945	COG2201	protein-glutamate methylesterase activity
DWQ65_07955	COG0835	chemotaxis
DWQ65_07960	COG2198	Histidine kinase
DWQ65_07960	COG0643	Histidine kinase
DWQ65_07990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DWQ65_07995	COG1882	Formate acetyltransferase
DWQ65_08015	COG1253	flavin adenine dinucleotide binding
DWQ65_08025	COG2801	Transposase and inactivated derivatives
DWQ65_08030	COG2801	Transposase and inactivated derivatives
DWQ65_08055	COG1757	Na H antiporter
DWQ65_08060	COG0357	Ribosomal RNA small subunit methyltransferase G
DWQ65_08090	COG0840	transmembrane signaling receptor activity
DWQ65_08125	COG0012	GTP binding
DWQ65_08140	COG1268	BioY protein
DWQ65_08145	COG1122	ATPase activity
DWQ65_08165	COG3959	Transketolase, thiamine diphosphate binding domain
DWQ65_08170	COG3958	Transketolase
DWQ65_08175	COG0584	glycerophosphoryl diester phosphodiesterase
DWQ65_08205	COG2801	Transposase and inactivated derivatives
DWQ65_08220	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DWQ65_08255	COG1181	Belongs to the D-alanine--D-alanine ligase family
DWQ65_08265	COG1132	(ABC) transporter
DWQ65_08270	COG1132	(ABC) transporter
DWQ65_08275	COG1132	(ABC) transporter
DWQ65_08280	COG1132	(ABC) transporter
DWQ65_08285	COG4608	Belongs to the ABC transporter superfamily
DWQ65_08290	COG0444	Belongs to the ABC transporter superfamily
DWQ65_08295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWQ65_08315	COG0492	ferredoxin-NADP+ reductase activity
DWQ65_08320	COG1472	Belongs to the glycosyl hydrolase 3 family
DWQ65_08340	COG0450	alkyl hydroperoxide reductase
DWQ65_08345	COG1349	DNA-binding transcription factor activity
DWQ65_08350	COG1105	Belongs to the carbohydrate kinase PfkB family
DWQ65_08355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_08355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_08355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DWQ65_08360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_08380	COG0640	Transcriptional regulator
DWQ65_08390	COG2217	Heavy metal translocating P-type atpase
DWQ65_08400	COG3177	Filamentation induced by cAMP protein fic
DWQ65_08410	COG3385	transposase activity
DWQ65_08445	COG0210	DNA helicase
DWQ65_08465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DWQ65_08475	COG1522	sequence-specific DNA binding
DWQ65_08480	COG0436	Aminotransferase
DWQ65_08485	COG1114	Component of the transport system for branched-chain amino acids
DWQ65_08490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DWQ65_08495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DWQ65_08500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DWQ65_08515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DWQ65_08520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DWQ65_08525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DWQ65_08535	COG1696	Membrane protein involved in D-alanine export
DWQ65_08550	COG0655	NAD(P)H dehydrogenase (quinone) activity
DWQ65_08555	COG0840	transmembrane signaling receptor activity
DWQ65_08570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DWQ65_08585	COG1252	NADH dehydrogenase
DWQ65_08595	COG1960	acyl-CoA dehydrogenase activity
DWQ65_08600	COG2086	electron transfer activity
DWQ65_08605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DWQ65_08635	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DWQ65_08640	COG1480	7TM receptor with intracellular HD hydrolase
DWQ65_08645	COG1702	phosphate starvation-inducible protein PhoH
DWQ65_08655	COG0018	arginyl-trna synthetase
DWQ65_08660	COG2235	arginine
DWQ65_08665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DWQ65_08670	COG0549	Belongs to the carbamate kinase family
DWQ65_08680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DWQ65_08685	COG0534	Mate efflux family protein
DWQ65_08690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DWQ65_08715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DWQ65_08720	COG1966	Carbon starvation protein
DWQ65_08730	COG1722	exodeoxyribonuclease VII activity
DWQ65_08735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DWQ65_08740	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DWQ65_08745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DWQ65_08770	COG0395	ABC-type sugar transport system, permease component
DWQ65_08780	COG1653	transport
DWQ65_08785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DWQ65_08795	COG2084	Dehydrogenase
DWQ65_08810	COG0330	HflC and HflK could
DWQ65_08850	COG2197	response regulator
DWQ65_08855	COG4585	Histidine kinase
DWQ65_08865	COG0166	Belongs to the GPI family
DWQ65_08915	COG0482	sulfurtransferase activity
DWQ65_08925	COG1674	ftsk spoiiie
DWQ65_08930	COG1968	undecaprenyl-diphosphatase activity
DWQ65_08940	COG0840	transmembrane signaling receptor activity
DWQ65_08965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DWQ65_08970	COG1752	Esterase of the alpha-beta hydrolase superfamily
DWQ65_08975	COG5341	Protein conserved in bacteria
DWQ65_08995	COG0823	Involved in the tonB-independent uptake of proteins
DWQ65_09015	COG0564	pseudouridine synthase activity
DWQ65_09015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DWQ65_09070	COG0519	Catalyzes the synthesis of GMP from XMP
DWQ65_09080	COG0519	Catalyzes the synthesis of GMP from XMP
DWQ65_09105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DWQ65_09105	COG0515	serine threonine protein kinase
DWQ65_09110	COG0811	peptide transport
DWQ65_09115	COG0848	biopolymer transport protein
DWQ65_09140	COG0203	ribosomal protein L17
DWQ65_09145	COG0202	RNA polymerase activity
DWQ65_09150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DWQ65_09160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DWQ65_09170	COG0200	Binds to the 23S rRNA
DWQ65_09175	COG1841	ribosomal large subunit assembly
DWQ65_09185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DWQ65_09190	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DWQ65_09195	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DWQ65_09205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DWQ65_09220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DWQ65_09225	COG0255	Belongs to the universal ribosomal protein uL29 family
DWQ65_09235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DWQ65_09240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DWQ65_09250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DWQ65_09255	COG0089	rRNA binding
DWQ65_09260	COG0088	Forms part of the polypeptide exit tunnel
DWQ65_09265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DWQ65_09270	COG0051	transcription antitermination factor activity, RNA binding
DWQ65_09275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DWQ65_09285	COG2823	Periplasmic or secreted lipoprotein
DWQ65_09285	COG1652	LysM domain
DWQ65_09290	COG2033	superoxide reductase activity
DWQ65_09295	COG1078	dGTPase activity
DWQ65_09320	COG1774	PSP1 C-terminal conserved region
DWQ65_09335	COG0739	heme binding
DWQ65_09345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DWQ65_09355	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DWQ65_09370	COG1419	protein localization to endoplasmic reticulum
DWQ65_09375	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DWQ65_09380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DWQ65_09385	COG1684	flagellar biosynthetic protein fliR
DWQ65_09390	COG1987	bacterial-type flagellum assembly
DWQ65_09395	COG1338	Plays a role in the flagellum-specific transport system
DWQ65_09405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DWQ65_09405	COG1776	CheC inhibitor of MCP methylation
DWQ65_09410	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DWQ65_09415	COG1580	Controls the rotational direction of flagella during chemotaxis
DWQ65_09420	COG1360	Flagellar Motor Protein
DWQ65_09440	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DWQ65_09465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DWQ65_09480	COG0840	transmembrane signaling receptor activity
DWQ65_09480	COG5278	phosphoserine phosphatase activity
DWQ65_09495	COG1164	Oligoendopeptidase f
DWQ65_09500	COG1690	Belongs to the RtcB family
DWQ65_09505	COG2213	PTS system mannitol-specific
DWQ65_09505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_09510	COG1349	DNA-binding transcription factor activity
DWQ65_09515	COG1063	alcohol dehydrogenase
DWQ65_09525	COG0235	Class ii aldolase
DWQ65_09530	COG0058	SHG alpha-glucan phosphorylase activity
DWQ65_09540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DWQ65_09555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWQ65_09555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DWQ65_09555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DWQ65_09580	COG1151	hydroxylamine reductase activity
DWQ65_09605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DWQ65_09640	COG0656	L-ascorbic acid biosynthetic process
DWQ65_09675	COG4536	flavin adenine dinucleotide binding
DWQ65_09680	COG1253	flavin adenine dinucleotide binding
DWQ65_09685	COG0800	Aldolase
DWQ65_09710	COG3706	GGDEF domain
DWQ65_09715	COG3706	GGDEF domain
DWQ65_09730	COG1653	transport
DWQ65_09740	COG0395	ABC-type sugar transport system, permease component
DWQ65_09765	COG0556	nucleotide-excision repair
DWQ65_09785	COG1102	Psort location Cytoplasmic, score
DWQ65_09795	COG0840	transmembrane signaling receptor activity
DWQ65_09815	COG0419	ATPase involved in DNA repair
DWQ65_09820	COG0420	3'-5' exonuclease activity
DWQ65_09825	COG0840	transmembrane signaling receptor activity
DWQ65_09840	COG0018	arginyl-trna synthetase
DWQ65_09880	COG2183	response to ionizing radiation
DWQ65_09890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DWQ65_09890	COG1747	RNA polymerase binding
DWQ65_09905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DWQ65_09920	COG1454	alcohol dehydrogenase
DWQ65_09920	COG1012	belongs to the aldehyde dehydrogenase family
DWQ65_09930	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DWQ65_09935	COG0442	prolyl-tRNA aminoacylation
DWQ65_09950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DWQ65_09965	COG0628	permease
DWQ65_09970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DWQ65_09980	COG1312	Catalyzes the dehydration of D-mannonate
DWQ65_09985	COG0246	Mannitol dehydrogenase
DWQ65_10005	COG1904	glucuronate isomerase
DWQ65_10010	COG3250	beta-galactosidase activity
DWQ65_10015	COG2211	Major facilitator Superfamily
DWQ65_10030	COG1349	DNA-binding transcription factor activity
DWQ65_10060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DWQ65_10065	COG0423	glycine-tRNA ligase activity
DWQ65_10075	COG0731	radical SAM domain protein
DWQ65_10085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DWQ65_10105	COG4555	ABC transporter
DWQ65_10110	COG2195	Cleaves the N-terminal amino acid of tripeptides
DWQ65_10115	COG0564	pseudouridine synthase activity
DWQ65_10120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DWQ65_10130	COG1924	4 iron, 4 sulfur cluster binding
DWQ65_10145	COG0765	amino acid transport
DWQ65_10155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DWQ65_10160	COG0733	neurotransmitter:sodium symporter activity
DWQ65_10170	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DWQ65_10175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DWQ65_10180	COG0592	DNA-directed DNA polymerase activity
DWQ65_10190	COG1687	branched-chain amino acid
DWQ65_10195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DWQ65_10200	COG0116	Belongs to the methyltransferase superfamily
DWQ65_10225	COG0446	pyridine nucleotide-disulphide oxidoreductase
DWQ65_10230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DWQ65_10235	COG1129	ABC transporter
DWQ65_10245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DWQ65_10260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DWQ65_10270	COG0670	Belongs to the BI1 family
DWQ65_10275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DWQ65_10300	COG0822	iron-sulfur transferase activity
DWQ65_10305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DWQ65_10310	COG0719	Fe-S assembly protein
DWQ65_10315	COG0719	Fe-S assembly protein
DWQ65_10355	COG1172	Belongs to the binding-protein-dependent transport system permease family
DWQ65_10360	COG1172	Belongs to the binding-protein-dependent transport system permease family
DWQ65_10365	COG1129	ABC transporter
DWQ65_10370	COG1879	ABC-type sugar transport system periplasmic component
DWQ65_10400	COG0653	protein targeting
DWQ65_10415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DWQ65_10480	COG0488	(ABC) transporter
DWQ65_10485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DWQ65_10490	COG0793	Belongs to the peptidase S41A family
DWQ65_10495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DWQ65_10510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DWQ65_10525	COG0673	inositol 2-dehydrogenase activity
DWQ65_10540	COG1191	sigma factor activity
DWQ65_10545	COG1847	R3H domain protein
DWQ65_10570	COG3956	TIGRFAM MazG family protein
DWQ65_10590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DWQ65_10595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DWQ65_10610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DWQ65_10630	COG1469	GTP cyclohydrolase I activity
DWQ65_10635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DWQ65_10650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DWQ65_10660	COG0557	exoribonuclease II activity
DWQ65_10680	COG2376	Dihydroxyacetone kinase
DWQ65_10705	COG1129	ABC transporter
DWQ65_10725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DWQ65_10745	COG1234	tRNA 3'-trailer cleavage
DWQ65_10750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DWQ65_10795	COG2078	PFAM AMMECR1 domain protein
DWQ65_10795	COG3885	ferrous iron binding
DWQ65_10805	COG1022	Amp-dependent synthetase and ligase
DWQ65_10810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DWQ65_10815	COG1486	melibiose metabolic process
DWQ65_10825	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
DWQ65_10830	COG2982	Protein involved in outer membrane biogenesis
DWQ65_10835	COG0697	spore germination
DWQ65_10840	COG0217	transcriptional regulatory protein
DWQ65_10850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DWQ65_10855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DWQ65_10860	COG0840	transmembrane signaling receptor activity
DWQ65_10875	COG3842	ATPase activity
DWQ65_10880	COG1178	ABC-type Fe3 transport system permease component
DWQ65_10885	COG3842	ATPase activity
DWQ65_10895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DWQ65_10910	COG2378	regulation of single-species biofilm formation
DWQ65_11005	COG0860	N-Acetylmuramoyl-L-alanine amidase
DWQ65_11040	COG2885	chlorophyll binding
DWQ65_11065	COG1131	(ABC) transporter
DWQ65_11085	COG0701	Predicted permease
DWQ65_11100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DWQ65_11130	COG1137	ATPase activity
DWQ65_11145	COG3723	Recombinational DNA repair protein, rece pathway
DWQ65_11165	COG5377	YqaJ viral recombinase family
DWQ65_11180	COG1132	(ABC) transporter
DWQ65_11185	COG4988	ABC transporter
DWQ65_11195	COG3142	Participates in the control of copper homeostasis
DWQ65_11200	COG1335	isochorismatase
DWQ65_11225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DWQ65_11240	COG1012	belongs to the aldehyde dehydrogenase family
DWQ65_11250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DWQ65_11275	COG1609	Transcriptional regulator
DWQ65_11295	COG0632	four-way junction helicase activity
DWQ65_11305	COG0457	Tetratricopeptide repeat
DWQ65_11310	COG0785	Cytochrome C biogenesis protein
DWQ65_11315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DWQ65_11335	COG0840	transmembrane signaling receptor activity
DWQ65_11350	COG3976	FMN-binding domain protein
DWQ65_11350	COG0431	NADPH-dependent FMN reductase
DWQ65_11350	COG1053	succinate dehydrogenase
DWQ65_11365	COG0205	6-phosphofructokinase activity
DWQ65_11395	COG1477	protein flavinylation
DWQ65_11445	COG5433	transposase activity
DWQ65_11455	COG1074	ATP-dependent DNA helicase activity
DWQ65_11460	COG2887	Belongs to the helicase family. UvrD subfamily
DWQ65_11475	COG2801	Transposase and inactivated derivatives
DWQ65_11485	COG2201	protein-glutamate methylesterase activity
DWQ65_11505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DWQ65_11510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DWQ65_11515	COG0215	cysteine-tRNA ligase activity
DWQ65_11530	COG1305	Transglutaminase-like
DWQ65_11535	COG0528	UMP kinase activity
DWQ65_11545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DWQ65_11550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DWQ65_11555	COG5002	protein histidine kinase activity
DWQ65_11555	COG2205	protein histidine kinase activity
DWQ65_11555	COG0784	Response regulator, receiver
DWQ65_11560	COG0457	Tetratricopeptide repeat
DWQ65_11565	COG0280	phosphate acetyltransferase
DWQ65_11575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DWQ65_11580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DWQ65_11590	COG0517	IMP dehydrogenase activity
DWQ65_11590	COG0516	GMP reductase activity
DWQ65_11640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DWQ65_11650	COG0084	hydrolase, TatD family'
DWQ65_11655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DWQ65_11660	COG3118	belongs to the thioredoxin family
DWQ65_11665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DWQ65_11685	COG0860	N-Acetylmuramoyl-L-alanine amidase
DWQ65_11700	COG2357	RelA SpoT domain protein
DWQ65_11705	COG0268	Binds directly to 16S ribosomal RNA
DWQ65_11710	COG0776	regulation of translation
DWQ65_11720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DWQ65_11730	COG1546	Belongs to the CinA family
DWQ65_11730	COG1058	Belongs to the CinA family
DWQ65_11735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DWQ65_11740	COG0254	rRNA binding
DWQ65_11770	COG0395	ABC-type sugar transport system, permease component
DWQ65_11775	COG1175	transmembrane transport
DWQ65_11790	COG0395	ABC-type sugar transport system, permease component
DWQ65_11810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DWQ65_11815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DWQ65_11815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DWQ65_11840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DWQ65_11855	COG0629	single-stranded DNA binding
DWQ65_11860	COG0205	6-phosphofructokinase activity
DWQ65_11870	COG0494	nUDIX hydrolase
DWQ65_11890	COG0488	(ABC) transporter
DWQ65_11895	COG0617	tRNA 3'-terminal CCA addition
DWQ65_11900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DWQ65_11905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DWQ65_11905	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DWQ65_11920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DWQ65_11945	COG0616	signal peptide processing
DWQ65_11950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DWQ65_11955	COG0681	Belongs to the peptidase S26 family
DWQ65_11975	COG0750	zinc metalloprotease
DWQ65_11980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DWQ65_11985	COG4589	Belongs to the CDS family
DWQ65_11990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DWQ65_11995	COG0233	cytoplasmic translational termination
DWQ65_12000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DWQ65_12005	COG0052	Belongs to the universal ribosomal protein uS2 family
DWQ65_12020	COG1136	(ABC) transporter
DWQ65_12025	COG0577	efflux transmembrane transporter activity
DWQ65_12030	COG0577	efflux transmembrane transporter activity
DWQ65_12035	COG0513	Belongs to the DEAD box helicase family
DWQ65_12040	COG1131	(ABC) transporter
DWQ65_12060	COG4585	Histidine kinase
DWQ65_12080	COG1136	(ABC) transporter
DWQ65_12090	COG0745	RESPONSE REGULATOR receiver
DWQ65_12095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DWQ65_12105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DWQ65_12110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DWQ65_12135	COG1254	Belongs to the acylphosphatase family
DWQ65_12170	COG0840	transmembrane signaling receptor activity
DWQ65_12190	COG0228	four-way junction DNA binding
DWQ65_12195	COG1837	Belongs to the UPF0109 family
DWQ65_12200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DWQ65_12205	COG0336	Belongs to the RNA methyltransferase TrmD family
DWQ65_12210	COG0335	large ribosomal subunit rRNA binding
DWQ65_12220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DWQ65_12260	COG0210	DNA helicase
DWQ65_12265	COG0733	neurotransmitter:sodium symporter activity
DWQ65_12275	COG0561	phosphatase activity
DWQ65_12285	COG3681	Belongs to the UPF0597 family
DWQ65_12295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DWQ65_12305	COG0142	geranyltranstransferase activity
DWQ65_12310	COG1609	Transcriptional regulator
DWQ65_12315	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DWQ65_12325	COG0395	ABC-type sugar transport system, permease component
DWQ65_12330	COG4209	transmembrane transport
DWQ65_12335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DWQ65_12345	COG3385	transposase activity
DWQ65_12350	COG2986	histidine ammonia-lyase
DWQ65_12355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DWQ65_12355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DWQ65_12355	COG1013	pyruvate-flavodoxin oxidoreductase activity
DWQ65_12355	COG0674	pyruvate-flavodoxin oxidoreductase activity
DWQ65_12360	COG0626	cystathionine gamma-synthase activity
DWQ65_12365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DWQ65_12370	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DWQ65_12380	COG1132	(ABC) transporter
DWQ65_12385	COG0653	protein targeting
DWQ65_12405	COG1366	Belongs to the anti-sigma-factor antagonist family
DWQ65_12420	COG0714	Associated with various cellular activities
DWQ65_12435	COG0569	domain protein
DWQ65_12440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DWQ65_12445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DWQ65_12450	COG3876	Protein conserved in bacteria
DWQ65_12485	COG0840	transmembrane signaling receptor activity
DWQ65_12500	COG0835	chemotaxis
DWQ65_12505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DWQ65_12510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DWQ65_12515	COG0497	DNA recombination
DWQ65_12530	COG0671	phosphoesterase, PA-phosphatase related
DWQ65_12535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DWQ65_12545	COG0601	transmembrane transport
DWQ65_12550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DWQ65_12555	COG0444	Belongs to the ABC transporter superfamily
DWQ65_12560	COG4608	Belongs to the ABC transporter superfamily
DWQ65_12575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DWQ65_12595	COG3385	transposase activity
DWQ65_12600	COG0534	Mate efflux family protein
DWQ65_12605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DWQ65_12615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DWQ65_12620	COG2911	Protein conserved in bacteria
DWQ65_12625	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DWQ65_12635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DWQ65_12650	COG3037	sugar-specific permease SgaT UlaA
DWQ65_12660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_12660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DWQ65_12665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DWQ65_12695	COG1175	transmembrane transport
DWQ65_12700	COG0395	ABC-type sugar transport system, permease component
DWQ65_12705	COG0514	ATP-dependent DNA helicase (RecQ)
DWQ65_12730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DWQ65_12740	COG1686	Belongs to the peptidase S11 family
DWQ65_12755	COG1418	mRNA catabolic process
DWQ65_12760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DWQ65_12790	COG2604	Protein of unknown function DUF115
DWQ65_12810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DWQ65_12820	COG0840	transmembrane signaling receptor activity
DWQ65_12845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DWQ65_12875	COG0517	IMP dehydrogenase activity
DWQ65_12885	COG0326	Molecular chaperone. Has ATPase activity
DWQ65_12905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DWQ65_12910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DWQ65_12915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DWQ65_12930	COG0300	oxidoreductase activity
DWQ65_12945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DWQ65_12975	COG2003	Belongs to the UPF0758 family