locus-tag class description FUT81_00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FUT81_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FUT81_00015 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FUT81_00020 ENOG4106C4Y Protein of unknown function (DUF721) FUT81_00030 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT81_00035 ENOG4105C8J )-transporter FUT81_00040 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT81_00045 ENOG4105EAD ABC transporter FUT81_00050 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FUT81_00055 ENOG4105F2I Transposase FUT81_00060 ENOG4105CDA abc transporter atp-binding protein FUT81_00070 ENOG4105CIZ coA-substrate-specific enzyme activase FUT81_00080 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FUT81_00090 ENOG4105CIN aminoacyl-histidine dipeptidase FUT81_00095 ENOG4108IUW ABC transporter FUT81_00115 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) FUT81_00125 ENOG4108ZVA radical SAM domain protein FUT81_00135 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) FUT81_00140 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FUT81_00145 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FUT81_00170 ENOG4105E98 transcriptional regulator DeoR family FUT81_00180 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT81_00185 ENOG4105CT4 transporter FUT81_00190 ENOG4105CNT hydrolase family 2 FUT81_00195 ENOG4105D2H Uronic isomerase FUT81_00200 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT81_00210 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT81_00215 ENOG4105DEI Mannitol dehydrogenase FUT81_00220 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FUT81_00230 ENOG4105II7 pyrroline-5-carboxylate reductase FUT81_00235 ENOG4105F4G Membrane FUT81_00250 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) FUT81_00255 ENOG4105VVB FUT81_00260 ENOG4106KG8 FUT81_00265 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FUT81_00270 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) FUT81_00280 ENOG4108EKI Dehydrogenase FUT81_00300 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT81_00360 ENOG4105C75 arginyL-tRNA synthetase FUT81_00375 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_00380 ENOG4107RFY SbcCD D subunit FUT81_00385 ENOG4105EYH Exonuclease FUT81_00390 ENOG4105DQ6 Transposase FUT81_00400 ENOG4105DQ6 Transposase FUT81_00410 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_00540 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT81_00650 ENOG41067S9 phage shock protein C, PspC FUT81_00675 ENOG4108RY1 ATP synthase, subunit E FUT81_00685 ENOG4107RVI Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) FUT81_00690 ENOG4107RQX Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit FUT81_00695 ENOG4108WBK V-type ATP synthase subunit D FUT81_00700 ENOG4107U1W v-type ATP synthase subunit I FUT81_00710 ENOG4107QNB Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FUT81_00715 ENOG4105WD1 Membrane FUT81_00720 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FUT81_00740 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FUT81_00745 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FUT81_00760 ENOG4105C5Y PTS System FUT81_00765 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FUT81_00770 ENOG4105CGK Exodeoxyribonuclease III FUT81_00780 ENOG4105VEM Conserved domain protein FUT81_00785 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT81_00790 ENOG4108JJ8 (ABC) transporter FUT81_00795 ENOG4108JJ9 ABC, transporter FUT81_00800 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FUT81_00805 ENOG4105C4M (Ubiquinol oxidase) subunit I FUT81_00830 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FUT81_00880 ENOG4108Y51 tRNA-binding protein FUT81_00885 ENOG4105CJR Integral membrane protein (MviN FUT81_00905 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FUT81_00910 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FUT81_00920 ENOG4105CUT histidyl-tRNA synthetase FUT81_00925 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FUT81_00930 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FUT81_00945 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FUT81_00970 ENOG4106RHC FUT81_00975 ENOG4108PJD permease FUT81_00985 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FUT81_01015 ENOG4108IUZ ABC transporter FUT81_01025 ENOG4105BZ1 (ABC) transporter FUT81_01030 ENOG4108JJ9 ABC, transporter FUT81_01040 ENOG4106N3A copper homeostasis protein cutc FUT81_01045 ENOG4105CHJ isochorismatase hydrolase FUT81_01065 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT81_01070 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) FUT81_01075 ENOG4105C26 Dehydrogenase FUT81_01085 ENOG4108JQ1 Dehydrogenase FUT81_01110 ENOG4105K95 (LipO)protein FUT81_01125 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FUT81_01130 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) FUT81_01135 ENOG4106AHS FUT81_01140 ENOG4107QIV Cytochrome c biogenesis protein FUT81_01145 ENOG4108IFH alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT81_01155 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_01165 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_01170 ENOG4107EFR Flavocytochrome c FUT81_01185 ENOG4105CTQ phosphohexokinase FUT81_01195 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_01215 ENOG4105CJ2 (LipO)protein FUT81_01265 ENOG410600T transposase FUT81_01275 ENOG4105F2I Transposase FUT81_01285 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FUT81_01290 ENOG4109031 FUT81_01300 ENOG4105DQ6 Transposase FUT81_01310 ENOG4105DQ6 Transposase FUT81_01320 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FUT81_01325 ENOG4105BZU Histidine kinase FUT81_01340 ENOG4105IJJ transcriptional regulator, crp fnr family FUT81_01345 ENOG4107QWW Cell wall formation (By similarity) FUT81_01350 ENOG4105C8N cysteinyl-tRNA synthetase FUT81_01365 ENOG4108KS2 transglutaminase domain protein FUT81_01370 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FUT81_01380 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) FUT81_01390 ENOG4105BZU Histidine kinase FUT81_01395 ENOG4105BZU Histidine kinase FUT81_01400 ENOG4107GWN repeat protein FUT81_01405 ENOG4108IJ2 phosphate acetyltransferase FUT81_01415 ENOG4105C2N RNA methyltransferase TrmH family group 3 FUT81_01420 ENOG4105CY0 Metallo-Beta-Lactamase FUT81_01425 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FUT81_01430 ENOG41067SE Tetr family transcriptional regulator FUT81_01440 ENOG4105BZ1 (ABC) transporter FUT81_01455 ENOG4107QKZ Ompa motb domain protein FUT81_01460 ENOG4108IPW abc transporter atp-binding protein FUT81_01465 ENOG4105CM4 permease protein FUT81_01490 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FUT81_01500 ENOG41069X2 FUT81_01505 ENOG4107THF Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FUT81_01510 ENOG4107TVT This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FUT81_01520 ENOG4105K4W Could be involved in septation (By similarity) FUT81_01525 ENOG4107SJN Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FUT81_01545 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT81_01570 ENOG4105G6Z alkaline phosphatase FUT81_01595 ENOG4107RIZ hflk protein FUT81_01605 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT81_01615 ENOG4107R2U Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) FUT81_01620 ENOG4106W1H FUT81_01630 ENOG4105CDA abc transporter atp-binding protein FUT81_01635 ENOG4105EAD ABC transporter FUT81_01640 ENOG4108HW3 (ABC) transporter FUT81_01650 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FUT81_01665 ENOG4107S6Z Na H antiporter FUT81_01670 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FUT81_01680 ENOG4105C0D helicase FUT81_01695 ENOG4105KRQ Addiction module toxin, Txe YoeB family FUT81_01705 ENOG4108HU6 Metal dependent phosphohydrolase FUT81_01715 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT81_01720 ENOG4107XHD Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FUT81_01740 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT81_01750 ENOG4105G9E FUT81_01755 ENOG4108J59 Extracellular solute-binding protein, family 5 FUT81_01760 ENOG4106FRC FUT81_01765 ENOG4105JTB FUT81_01770 ENOG4108V2B Flagellar filament outer layer protein FUT81_01780 ENOG4105D2N Aldolase FUT81_01800 ENOG4107SFZ crispr-associated protein FUT81_01820 ENOG41067MG lrgb family FUT81_01830 ENOG4108ZV0 ABC transporter, permease FUT81_01835 ENOG4108TWB ABC transporter (Permease FUT81_01845 ENOG4108SSC basic membrane FUT81_01860 ENOG41084P6 50S ribosomal protein l28 FUT81_01870 ENOG4105CQ7 ATP-dependent helicase FUT81_01880 ENOG4105C5I Dehydrogenase FUT81_01885 ENOG4105D6U Sodium Glutamate Symporter FUT81_01895 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein FUT81_01900 ENOG4105D9Q decarboxylase (Beta subunit) FUT81_01905 ENOG4105DMN coenzyme A transferase FUT81_01910 ENOG4107UHT Glutaconate CoA-transferase FUT81_01915 ENOG4107QX3 carboxylase FUT81_01920 ENOG4105D6U Sodium Glutamate Symporter FUT81_01930 ENOG4105CMH dehydratase FUT81_01935 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase FUT81_01955 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT81_01975 ENOG4105C7N Xanthine uracil vitamin C permease FUT81_01980 ENOG4108UIC UPF0340 protein FUT81_01985 ENOG4108UIC UPF0340 protein FUT81_02010 ENOG4105EEI dihydropteroate synthase FUT81_02015 ENOG4105CGH 5'-nucleotidase FUT81_02150 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_02155 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FUT81_02160 ENOG4107QNG Phosphoribosylglycinamide synthetase FUT81_02165 ENOG4105DC1 bifunctional purine biosynthesis protein purh FUT81_02190 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FUT81_02195 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT81_02200 ENOG4108HM4 ABC transporter FUT81_02205 ENOG4105D38 putrescine abc transporter FUT81_02210 ENOG4105F38 ABC transporter, permease FUT81_02215 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_02425 ENOG4105M7P phage repressor FUT81_02505 ENOG4105CEC DNA methylase N-4 N-6 FUT81_02620 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT81_02725 ENOG4105C37 (CBS) domain FUT81_02730 ENOG4108JU6 CBS domain protein FUT81_02750 ENOG4105D06 uba thif-type nad fad binding protein FUT81_02755 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_02775 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FUT81_02780 ENOG4107V9H nitrite transporter FUT81_02795 ENOG4105ZAM anti-sigma-28 factor flgm family protein FUT81_02800 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FUT81_02810 ENOG4105CSM endonuclease III FUT81_02815 ENOG4105C8J )-transporter FUT81_02820 ENOG4105C0F tryptophanase EC 4.1.99.1 FUT81_02835 ENOG4107QMH DNA methylase FUT81_02840 ENOG4105D8D Type III FUT81_02850 ENOG4105DQ6 Transposase FUT81_02860 ENOG4108DBC nitroreductase FUT81_02865 ENOG4105C3J Cysteine desulfurase FUT81_02875 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FUT81_02885 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FUT81_02915 ENOG4105DAN ATP-dependent protease FUT81_02940 ENOG4105CGH 5'-nucleotidase FUT81_02950 ENOG4105DZW Dipeptidase FUT81_02955 ENOG4105CV8 reductase FUT81_02970 ENOG4105DRR Transcriptional regulator, GntR family FUT81_02990 ENOG4105E0M Sulfatase FUT81_02995 ENOG4105E0M Sulfatase FUT81_03235 ENOG4105D6S protein involved in catabolism of external DNA FUT81_03245 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FUT81_03255 ENOG4105C37 (CBS) domain FUT81_03270 ENOG4105CGH 5'-nucleotidase FUT81_03280 ENOG4105CB5 ATP-dependent DNA helicase recG FUT81_03285 ENOG4105C22 threonyL-tRNA synthetase FUT81_03290 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT81_03295 ENOG41082MQ UPF0178 protein FUT81_03300 ENOG4105EIP mannose-6-phosphate isomerase FUT81_03305 ENOG4106BMT Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) FUT81_03310 ENOG4106BH8 FUT81_03315 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FUT81_03320 ENOG41084MZ 50S ribosomal protein L35 FUT81_03325 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FUT81_03330 ENOG4105C0H protease FUT81_03335 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FUT81_03350 ENOG41083NY Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FUT81_03355 ENOG4105E66 phosphoriboisomerase A FUT81_03360 ENOG4107YNV 3-dehydroquinate dehydratase FUT81_03375 ENOG41076UM multiple antibiotic resistance (MarC)-related protein FUT81_03380 ENOG4105DQ6 Transposase FUT81_03395 ENOG4105F2I Transposase FUT81_03415 ENOG4105DRS transport system, permease FUT81_03425 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FUT81_03440 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FUT81_03445 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FUT81_03450 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FUT81_03455 ENOG4105DTN riboflavin biosynthesis protein ribF FUT81_03460 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FUT81_03465 ENOG41080JB Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FUT81_03475 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FUT81_03480 ENOG4105CHV Transcription elongation factor NusA FUT81_03485 ENOG410854D Required for maturation of 30S ribosomal subunits (By similarity) FUT81_03490 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FUT81_03510 ENOG4105BZ1 (ABC) transporter FUT81_03515 ENOG4105BZ1 (ABC) transporter FUT81_03530 ENOG4108UHU Aldolase FUT81_03550 ENOG4105BZU Histidine kinase FUT81_03555 ENOG4105BZU Histidine kinase FUT81_03570 ENOG4108JE9 extracellular solute-binding protein family 1 FUT81_03580 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component FUT81_03605 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FUT81_03615 ENOG4105DFU Cell wall formation (By similarity) FUT81_03625 ENOG4108Z4J Cytidine monophosphate kinase FUT81_03725 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT81_03870 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FUT81_03875 ENOG4106N2C FUT81_03885 ENOG4107R2W ABC transporter, permease FUT81_03890 ENOG4105C2J ABC transporter FUT81_03895 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT81_03915 ENOG4108NF7 phage-type endonuclease FUT81_03935 ENOG4108PNI recT protein FUT81_03960 ENOG4105Z8H single-stranded DNA-binding protein FUT81_04000 ENOG4105C5X domain protein FUT81_04010 ENOG41062BZ domain protein FUT81_04020 ENOG4107QW4 alcohol dehydrogenase FUT81_04030 ENOG4105K4H Nlp p60 protein FUT81_04035 ENOG4105CEY Amp-dependent synthetase and ligase FUT81_04040 ENOG41083CW dedA protein FUT81_04045 ENOG4107QMG Nad synthetase FUT81_04055 ENOG410684W FUT81_04060 ENOG4105KG3 cytidine deaminase FUT81_04065 ENOG4105C1A potassium transporter peripheral membrane FUT81_04070 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) FUT81_04085 ENOG4108UT2 hemolysin iii FUT81_04100 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_04105 ENOG4108JA2 transcriptioN-repair coupling factor FUT81_04115 ENOG4105CJW magnesium transporter FUT81_04120 ENOG4105D6E homoserine dehydrogenase FUT81_04125 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FUT81_04130 ENOG4105CVG Homoserine O-transsuccinylase FUT81_04140 ENOG4105DR4 Methyltransferase FUT81_04145 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FUT81_04155 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FUT81_04160 ENOG4108JQ7 (ABC) transporter FUT81_04175 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT81_04185 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT81_04190 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FUT81_04205 ENOG4105CKI cobalamin synthesis protein FUT81_04215 ENOG4105E98 transcriptional regulator DeoR family FUT81_04225 ENOG4105D7K pfkb domain protein FUT81_04230 ENOG4105D2N Aldolase FUT81_04235 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT81_04240 ENOG4105CI2 imidazolone-5-propionate hydrolase FUT81_04275 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FUT81_04285 ENOG4105C1J atp-dependent rna helicase FUT81_04305 ENOG4105CJ1 ABC, transporter FUT81_04315 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT81_04320 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FUT81_04325 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FUT81_04330 ENOG4105C2J ABC transporter FUT81_04335 ENOG4105CNN ABC, transporter FUT81_04350 ENOG4105C28 cystathionine FUT81_04360 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component FUT81_04370 ENOG4105F2I Transposase FUT81_04380 ENOG4105CUY Mechanosensitive ion channel FUT81_04385 ENOG4105DJ0 Poly(A) Polymerase FUT81_04405 ENOG4105D7A ATP-binding protein FUT81_04415 ENOG4105DQ6 Transposase FUT81_04450 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_04460 ENOG4108RCM Nitroreductase FUT81_04470 ENOG41073FS FUT81_04480 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT81_04485 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT81_04500 ENOG4107TFB basic membrane FUT81_04505 ENOG4108JQ9 ABC transporter FUT81_04510 ENOG4105UIB (ABC) transporter FUT81_04520 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FUT81_04570 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FUT81_04585 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FUT81_04590 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FUT81_04595 ENOG4107EFR Flavocytochrome c FUT81_04600 ENOG4105CBX hi0933 family FUT81_04610 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FUT81_04705 ENOG4105KT7 mgtC SapB transporter FUT81_04710 ENOG4106ARS FUT81_04725 ENOG4107R21 site-determining protein FUT81_04735 ENOG4107WGG Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) FUT81_04740 ENOG4105DF5 DNA topoisomerase IV, subunit A FUT81_04755 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FUT81_04760 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT81_04765 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FUT81_04800 ENOG4105BZU Histidine kinase FUT81_04810 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FUT81_04815 ENOG4105F8V Hydrolase, tatD family FUT81_04820 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT81_04825 ENOG4105WJX transcriptional regulator MERR family FUT81_04835 ENOG4106QD2 FUT81_04840 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FUT81_04845 ENOG4105C3F Signal peptidase i FUT81_04850 ENOG4105CSA Coproporphyrinogen iii oxidase FUT81_04855 ENOG4106YRG FUT81_04860 ENOG41084AY Binds together with S18 to 16S ribosomal RNA (By similarity) FUT81_04865 ENOG4105Z8H single-stranded DNA-binding protein FUT81_04870 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FUT81_04875 ENOG4105K9Q Binds to the 23S rRNA (By similarity) FUT81_04880 ENOG4105CDU Replicative dna helicase FUT81_04925 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT81_04930 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT81_04965 ENOG4105DM4 PTS System FUT81_04970 ENOG41077G2 FUT81_04980 ENOG4105MPN Membrane FUT81_04990 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FUT81_04995 ENOG4105CFG Acts as a chaperone (By similarity) FUT81_05000 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FUT81_05005 ENOG4108JIP Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity) FUT81_05010 ENOG4107RVI Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity) FUT81_05030 ENOG4107WUB V-type ATPase 116 kDa subunit FUT81_05045 ENOG4105DM4 PTS System FUT81_05050 ENOG4106447 Preprotein translocase subunit SecG FUT81_05065 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) FUT81_05070 ENOG4105DD7 kinase (PfkB family FUT81_05075 ENOG4107YM1 mraZ protein FUT81_05080 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FUT81_05090 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FUT81_05095 ENOG4105CNI cell division protein FtsW FUT81_05100 ENOG410812A polypeptide-transport-associated domain protein, FtsQ-type FUT81_05105 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FUT81_05110 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FUT81_05115 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT81_05125 ENOG4105C79 DNA protecting protein DprA FUT81_05130 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FUT81_05135 ENOG4108I7H Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FUT81_05140 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FUT81_05145 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FUT81_05155 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FUT81_05160 ENOG4108ZC9 flagellar basal-body rod protein flgc FUT81_05165 ENOG41069WH flagellar hook-basal body complex FUT81_05170 ENOG4107U2N Flagellar M-ring protein FUT81_05175 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT81_05180 ENOG4105W2B Flagellar assembly protein FUT81_05185 ENOG4108JIR Flagellum-specific ATP synthase FUT81_05200 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FUT81_05215 ENOG4105Q84 sucrose synthase FUT81_05240 ENOG4105C6F GntR Family Transcriptional Regulator FUT81_05275 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FUT81_05280 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FUT81_05285 ENOG41090QR FUT81_05300 ENOG4105CH2 amidohydrolase FUT81_05315 ENOG4105CSA Coproporphyrinogen iii oxidase FUT81_05325 ENOG4108V1T peptidylprolyl cis-trans isomerase FUT81_05350 ENOG4108RVA ribokinase FUT81_05355 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FUT81_05360 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FUT81_05370 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_05410 ENOG4105DQ6 Transposase FUT81_05415 ENOG4105CTQ phosphohexokinase FUT81_05420 ENOG4105HCZ FUT81_05435 ENOG4105EAH synthase FUT81_05445 ENOG4105D48 metallophosphoesterase FUT81_05475 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FUT81_05480 ENOG4107JR8 Colicin v production protein FUT81_05485 ENOG4107QRG dna polymerase iii FUT81_05490 ENOG4105BZU Histidine kinase FUT81_05495 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT81_05545 ENOG4105CE1 Ferrous iron transport protein b FUT81_05565 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT81_05570 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FUT81_05575 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FUT81_05580 ENOG41084YP 30S ribosomal protein S21 FUT81_05590 ENOG4108346 Beta-lactamase domain protein FUT81_05600 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FUT81_05605 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FUT81_05610 ENOG4105C98 muts2 protein FUT81_05625 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FUT81_05630 ENOG4105CGA flagellar basal-body rod protein FlgG FUT81_05635 ENOG410680E Flagellar protein FUT81_05640 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FUT81_05650 ENOG4108YZY peptidylprolyl cis-trans isomerase FUT81_05660 ENOG4108M1M outer membrane lipoprotein-sorting protein FUT81_05670 ENOG4108RZE Tetr family transcriptional regulator FUT81_05680 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) FUT81_05685 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator FUT81_05690 ENOG4105D48 metallophosphoesterase FUT81_05710 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FUT81_05735 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FUT81_05745 ENOG4105DUA (citrate (pro-3S)-lyase ligase FUT81_05755 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT81_05765 ENOG41081IW Inherit from COG: Membrane FUT81_05775 ENOG4105FEU K -dependent Na -Ca exchanger FUT81_05790 ENOG4105EAM Na Pi-cotransporter FUT81_05795 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FUT81_05810 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FUT81_05815 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FUT81_05820 ENOG4105W0I repeat-containing protein FUT81_05830 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FUT81_05840 ENOG4106TCE FUT81_05845 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FUT81_05870 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FUT81_05885 ENOG4105N98 Capsule biosynthesis protein capB FUT81_05890 ENOG4105C0B DNA polymerase III (alpha subunit) FUT81_05895 ENOG41067XK integral membrane protein FUT81_05900 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FUT81_05905 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FUT81_05920 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FUT81_05925 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT81_05935 ENOG4106SWD FUT81_05945 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FUT81_05955 ENOG4105E2D ec 3.2.1.52 FUT81_05960 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FUT81_05980 ENOG4105CFP Peptidase U32 FUT81_06005 ENOG4107W7Y Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FUT81_06015 ENOG41090Q2 FUT81_06050 ENOG4105WN5 stage II sporulation protein FUT81_06060 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FUT81_06070 ENOG4105K46 50S ribosomal protein l27 FUT81_06075 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FUT81_06080 ENOG4107X4V Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FUT81_06125 ENOG4107R39 (ABC) transporter FUT81_06130 ENOG4107SJW iron permease, FTR1 FUT81_06135 ENOG4108SDV Periplasmic Protein FUT81_06150 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT81_06165 ENOG4105C19 ABC transporter FUT81_06185 ENOG4105I7V membrAne FUT81_06190 ENOG4105EA8 2-Nitropropane dioxygenase FUT81_06195 ENOG4105ESV Glycosyl transferase, family 4 FUT81_06215 ENOG4105DR5 peptidase FUT81_06225 ENOG4108JQC penicillin-binding protein 1A FUT81_06235 ENOG41082BE ankyrin repeat-containing protein FUT81_06240 ENOG4105Z8J FUT81_06255 ENOG4106AG2 FUT81_06265 ENOG41068FD FUT81_06270 ENOG4105CU9 asparagine synthetase A FUT81_06275 ENOG4108V0P LemA family FUT81_06285 ENOG4105HA9 of methanol dehydrogenase type FUT81_06300 ENOG41061XC FUT81_06315 ENOG4107R3E Citrate transporter FUT81_06320 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FUT81_06335 ENOG4105CGA flagellar basal-body rod protein FlgG FUT81_06340 ENOG4108S3Y transcriptional regulator FUT81_06345 ENOG4105C5Y PTS System FUT81_06350 ENOG4108HCJ Hydrolase FUT81_06355 ENOG4105CS2 ec 3.2.1.21 FUT81_06360 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FUT81_06365 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT81_06380 ENOG4107XH4 PPIases accelerate the folding of proteins (By similarity) FUT81_06395 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FUT81_06410 ENOG4105VG0 50S ribosomal protein l34 FUT81_06420 ENOG4107S1W 4-alpha-glucanotransferase FUT81_06425 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FUT81_06440 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FUT81_06445 ENOG4105KZ7 phosphocarrier protein hpr FUT81_06460 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FUT81_06475 ENOG4105W5Q DNA repair protein (RadC FUT81_06535 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) FUT81_06550 ENOG4105C5S asparaginyl-tRNA synthetase FUT81_06555 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_06570 ENOG4107QSA Oxaloacetate decarboxylase FUT81_06575 ENOG4105D9Q decarboxylase (Beta subunit) FUT81_06580 ENOG4105EAB amino acid AbC transporter FUT81_06585 ENOG4108HW3 (ABC) transporter FUT81_06590 ENOG4108120 Pasta domain protein FUT81_06600 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FUT81_06605 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FUT81_06610 ENOG4106BN6 FUT81_06615 ENOG4108JDX DNA polymerase iii, epsilon subunit FUT81_06625 ENOG41080UU 5-formyltetrahydrofolate cyclo-ligase FUT81_06630 ENOG4106GZE FUT81_06685 ENOG4105CVR type I restriction-modification system FUT81_06700 ENOG4105II7 pyrroline-5-carboxylate reductase FUT81_06715 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FUT81_06720 ENOG4106XJW FUT81_06735 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FUT81_06745 ENOG4108QUE repeat-containing protein FUT81_06750 ENOG4105FA0 parb-like partition protein FUT81_06755 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FUT81_06760 ENOG4105KME endoribonuclease L-psp FUT81_06770 ENOG4105C1B dTDP-glucose 4-6-dehydratase FUT81_06780 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FUT81_06790 ENOG4105DMT epimerase dehydratase FUT81_06810 ENOG4105KPE licD family FUT81_06845 ENOG4107STF Involved in phosphonate degradation (By similarity) FUT81_06850 ENOG4105DTI Phosphonopyruvate decarboxylase FUT81_06885 ENOG4105C22 threonyL-tRNA synthetase FUT81_06915 ENOG4107RBJ symporter FUT81_06925 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_06955 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT81_06965 ENOG4105MJ2 Competence protein FUT81_06980 ENOG4105E9H Lytic Murein transglycosylase FUT81_06995 ENOG4105DR5 peptidase FUT81_07000 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FUT81_07005 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FUT81_07010 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FUT81_07035 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT81_07070 ENOG4105Z8H single-stranded DNA-binding protein FUT81_07095 ENOG4108PNI recT protein FUT81_07115 ENOG4108NF7 phage-type endonuclease FUT81_07130 ENOG4105BZ1 (ABC) transporter FUT81_07135 ENOG4105BZ1 (ABC) transporter FUT81_07140 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FUT81_07160 ENOG41062VP FUT81_07190 ENOG4105BZ1 (ABC) transporter FUT81_07195 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FUT81_07200 ENOG41071ED FUT81_07215 ENOG4106UUF FUT81_07230 ENOG4105SXG FUT81_07235 ENOG4105ZF0 Lipoprotein FUT81_07240 ENOG4105C26 Dehydrogenase FUT81_07245 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT81_07250 ENOG4105CNN ABC, transporter FUT81_07255 ENOG4105C2J ABC transporter FUT81_07260 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FUT81_07410 ENOG4105F2I Transposase FUT81_07530 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FUT81_07540 ENOG4105CJN penicillin-binding protein FUT81_07560 ENOG4107MD5 glycoside hydrolase, family FUT81_07565 ENOG41063XV FUT81_07570 ENOG4108ESY Metal dependent phosphohydrolase FUT81_07575 ENOG4105EJQ L-serine dehydratase FUT81_07585 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FUT81_07610 ENOG4108RAC Rubrerythrin FUT81_07620 ENOG4106SUR Protein of unknown function DUF115 FUT81_07630 ENOG4105DSE periplasmic solute binding protein FUT81_07635 ENOG4105FDK ABC transporter FUT81_07640 ENOG4105FAV ABC, transporter FUT81_07645 ENOG4105CH2 amidohydrolase FUT81_07665 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FUT81_07685 ENOG4105MUZ Protein of unknown function DUF2620 FUT81_07690 ENOG4106M0N transport system permease protein FUT81_07705 ENOG4106PKC pyridoxal phosphate binding FUT81_07710 ENOG4108626 Racemase FUT81_07715 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FUT81_07750 ENOG4106MPK FUT81_07755 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FUT81_07770 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FUT81_07785 ENOG41066A3 ATP guanido phosphotransferase FUT81_07815 ENOG4108UN4 phage SPO1 DNA polymerase-related protein FUT81_07825 ENOG4105C5H ABC transporter FUT81_07825 ENOG4105C5H ABC transporter FUT81_07835 ENOG41089XN FUT81_07850 ENOG4105EI2 Pseudouridine synthase FUT81_07870 ENOG4106SAP FUT81_07875 ENOG4107VE5 flagellar hook-associated protein FUT81_07885 ENOG4105I03 Flagellin FUT81_07890 ENOG4105I03 Flagellin FUT81_07900 ENOG4105C0P Mg chelatase subunit ChlI FUT81_07915 ENOG41071ZZ FUT81_07935 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FUT81_07940 ENOG4105K8N protein family UPF0079, ATPase FUT81_07950 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT81_07970 ENOG4105D98 threonine synthase FUT81_07985 ENOG4105CTZ aminopeptidase c FUT81_07995 ENOG4108UW5 maltose o-acetyltransferase FUT81_08000 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FUT81_08005 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FUT81_08025 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FUT81_08035 ENOG4105ZFX FUT81_08050 ENOG4108TSD Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT81_08065 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT81_08070 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FUT81_08075 ENOG4108MIC Mg-protoporphyrin IX methyl transferase FUT81_08080 ENOG4105BZW Glycerate kinase FUT81_08085 ENOG4105C6Z Gluconate FUT81_08105 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) FUT81_08115 ENOG4105EV2 VWA domain protein interacting with AAA ATPase FUT81_08160 ENOG4105BZ1 (ABC) transporter FUT81_08165 ENOG4105BZ1 (ABC) transporter FUT81_08170 ENOG4105EHG Permease protein FUT81_08175 ENOG4105E0A ABC, transporter FUT81_08180 ENOG4105F2I Transposase FUT81_08215 ENOG4105DXX methyltransferase FUT81_08285 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FUT81_08310 ENOG4108JJB ABC transporter FUT81_08330 ENOG4107QMH DNA methylase FUT81_08350 ENOG4105CHY citrate lyase, alpha FUT81_08360 ENOG4105XGS Covalent carrier of the coenzyme of citrate lyase (By similarity) FUT81_08395 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FUT81_08400 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT81_08430 ENOG4105CVA phosphate FUT81_08440 ENOG4105E2Z phosphate ABC transporter (Permease FUT81_08445 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FUT81_08450 ENOG4108UTW Plays a role in the regulation of phosphate uptake FUT81_08455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FUT81_08460 ENOG4105BZU Histidine kinase FUT81_08465 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_08470 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FUT81_08480 ENOG41083MR nifu domain-containing protein FUT81_08500 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_08505 ENOG4105MQ3 flagellar protein FliS FUT81_08510 ENOG4106VWR FUT81_08515 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FUT81_08520 ENOG4106B9X FUT81_08525 ENOG4105DR9 pseudouridine synthase FUT81_08530 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FUT81_08535 ENOG4105BZU Histidine kinase FUT81_08555 ENOG4105WH1 Two component transcriptional regulator luxr family FUT81_08570 ENOG4105BZ8 glutamate synthase FUT81_08575 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein FUT81_08580 ENOG4108S10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FUT81_08595 ENOG4105E5D amino acid FUT81_08635 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FUT81_08640 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) FUT81_08685 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FUT81_08695 ENOG41085YX 50S ribosomal protein L32 FUT81_08700 ENOG41084E5 Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FUT81_08705 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FUT81_08710 ENOG4105F2I Transposase FUT81_08715 ENOG4105F0S class B acid phosphatase FUT81_08725 ENOG4105FE9 pseudouridine synthase FUT81_08730 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FUT81_08735 ENOG4105MBR gumn family FUT81_08740 ENOG4105C31 Tryptophanyl-tRNA synthetase FUT81_08750 ENOG4105CZV ABC transporter FUT81_08760 ENOG4107QJD pyruvate phosphate dikinase FUT81_08765 ENOG4108SXE FUT81_08770 ENOG41073RW Cytoplasmic filament protein A FUT81_08775 ENOG4105YQK von Willebrand factor type A domain FUT81_08790 ENOG4105DK7 lysyl-tRNA synthetase FUT81_08805 ENOG4106C6A Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FUT81_08810 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT81_08815 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT81_08820 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) FUT81_08825 ENOG4108VZM 50s ribosomal protein L10 FUT81_08830 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) FUT81_08835 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) FUT81_08840 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FUT81_08855 ENOG41084ED 50S ribosomal protein L33 FUT81_08865 ENOG4108Z29 Flavodoxin FUT81_08880 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FUT81_08885 ENOG4105C2J ABC transporter FUT81_08890 ENOG4105CNN ABC, transporter FUT81_08895 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FUT81_08930 ENOG4105C0H protease FUT81_08935 ENOG4105CE4 GlcNAc 6-P deacetylase FUT81_08945 ENOG4108IXY short-chain dehydrogenase reductase FUT81_08955 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FUT81_08965 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FUT81_08980 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT81_08985 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FUT81_08990 ENOG4105W87 Cbs domain FUT81_08995 ENOG4108IV0 ABC, transporter FUT81_09000 ENOG4105C0Z ABC transporter FUT81_09005 ENOG4105CF8 branched-chain amino acid ABC transporter, permease FUT81_09010 ENOG4105C32 Amino acid ABC transporter (Permease) FUT81_09020 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FUT81_09025 ENOG41068UM RNA Polymerase FUT81_09035 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_09045 ENOG4106U5D Septum formation initiator FUT81_09050 ENOG410698I FUT81_09060 ENOG4105X4X Protein of unknown function DUF115 FUT81_09065 ENOG41090QV Protein of unknown function DUF115 FUT81_09095 ENOG4105DJV ribulose-phosphate 3-epimerase FUT81_09100 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) FUT81_09110 ENOG4105E2D ec 3.2.1.52 FUT81_09115 ENOG4105DZ1 carboxypeptidase FUT81_09125 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT81_09355 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT81_09360 ENOG4105DRS transport system, permease FUT81_09365 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FUT81_09395 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FUT81_09400 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein FUT81_09410 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC FUT81_09425 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) FUT81_09435 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FUT81_09445 ENOG410805Y Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FUT81_09455 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FUT81_09460 ENOG4107QJQ Mate efflux family protein FUT81_09465 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FUT81_09470 ENOG410691R Modulates RecA activity (By similarity) FUT81_09475 ENOG4108UJD 30S ribosomal protein S9 FUT81_09480 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FUT81_09490 ENOG4108JQ7 (ABC) transporter FUT81_09500 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT81_09505 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FUT81_09510 ENOG4107QSI ABC, transporter FUT81_09515 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FUT81_09520 ENOG410841Q phosphoesterase PA-phosphatase related protein FUT81_09535 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FUT81_09540 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FUT81_09545 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT81_09550 ENOG4105YFD chemotaxis, protein FUT81_09565 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_09585 ENOG4105EMN RNA polymerase sigma factor FUT81_09600 ENOG4105EHZ conserved protein UCP016719 FUT81_09610 ENOG4105CZN Potassium uptake protein FUT81_09615 ENOG4107ZYR domain protein FUT81_09630 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FUT81_09645 ENOG4105WN5 stage II sporulation protein FUT81_09665 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FUT81_09670 ENOG4105BZ1 (ABC) transporter FUT81_09675 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) FUT81_09680 ENOG4105C7B Threonine dehydratase FUT81_09685 ENOG4105C28 cystathionine FUT81_09695 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) FUT81_09705 ENOG4105F2I Transposase FUT81_09715 ENOG4105C94 Transporter FUT81_09725 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component FUT81_09735 ENOG4105CKB glycosidase FUT81_09755 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) FUT81_09765 ENOG4105CEM UPF0597 protein FUT81_09775 ENOG4108KP7 hydrolase FUT81_09780 ENOG4105T73 FUT81_09785 ENOG4105C8J )-transporter FUT81_09795 ENOG4105TQV FUT81_09820 ENOG41082I4 UPF0102 protein FUT81_09825 ENOG4105CPI Metal Dependent Phosphohydrolase FUT81_09830 ENOG4105D00 flagellar biosynthetic protein flhB FUT81_09840 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FUT81_09845 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FUT81_09850 ENOG4107GQ3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FUT81_09855 ENOG4105VB6 UPF0109 protein FUT81_09860 ENOG4105K5M 30s ribosomal protein S16 FUT81_09895 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 FUT81_09915 ENOG4107GGS FUT81_09920 ENOG4107R05 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT81_09925 ENOG41080VC Galactokinase (EC 2.7.1.6) FUT81_09930 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FUT81_09945 ENOG4106R77 FUT81_09955 ENOG4105DR5 peptidase FUT81_09970 ENOG4105DR5 peptidase FUT81_09975 ENOG4105BZ1 (ABC) transporter FUT81_09980 ENOG4105DWF phosphomethylpyrimidine kinase FUT81_09985 ENOG4105C8T Leucyl-tRNA synthetase FUT81_10005 ENOG4106JH4 FUT81_10010 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FUT81_10015 ENOG4105DN3 alpha-2-macroglobulin domain protein FUT81_10035 ENOG4107QJE Chromosome Partitioning Protein FUT81_10040 ENOG4105FA0 parb-like partition protein FUT81_10050 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FUT81_10300 ENOG4105CEC DNA methylase N-4 N-6 FUT81_10370 ENOG4105M7P phage repressor FUT81_10385 ENOG4105C1J atp-dependent rna helicase FUT81_10390 ENOG4107RBB ABC transporter, permease FUT81_10395 ENOG4107RBB ABC transporter, permease FUT81_10400 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FUT81_10415 ENOG4105CE9 30S ribosomal protein S2 FUT81_10420 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) FUT81_10425 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FUT81_10430 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FUT81_10435 ENOG4105KNE Phosphatidate cytidylyltransferase FUT81_10440 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FUT81_10445 ENOG4105DZP Membrane-associated zinc metalloprotease FUT81_10450 ENOG41062Z1 FUT81_10455 ENOG4105X1A FUT81_10470 ENOG4105C3F Signal peptidase i FUT81_10475 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FUT81_10480 ENOG4105D07 Signal peptide peptidase, SppA FUT81_10505 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FUT81_10520 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT81_10525 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FUT81_10595 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_10630 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FUT81_10640 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FUT81_10660 ENOG4105DIH basic membrane FUT81_10665 ENOG4108JQ9 ABC transporter FUT81_10670 ENOG4105UIB (ABC) transporter FUT81_10705 ENOG4105E4P ATPase (AAA FUT81_10745 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT81_10800 ENOG4105C5H ABC transporter FUT81_10805 ENOG4105I76 (LipO)protein FUT81_10820 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FUT81_10830 ENOG4107RJF diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) FUT81_10965 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FUT81_11060 ENOG41082Y9 Single-strand binding protein FUT81_11075 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT81_11085 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FUT81_11090 ENOG4108R6K riboflavin synthase, subunit alpha FUT81_11100 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FUT81_11105 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FUT81_11120 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FUT81_11140 ENOG4105DRS transport system, permease FUT81_11155 ENOG4105CA9 Pyruvate kinase FUT81_11170 ENOG41082DI 50s ribosomal protein l31 FUT81_11175 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FUT81_11180 ENOG4105CEV competence damage-inducible protein FUT81_11190 ENOG4107RI4 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FUT81_11200 ENOG41083IJ DNA-binding protein FUT81_11205 ENOG41086BH Binds directly to 16S ribosomal RNA (By similarity) FUT81_11215 ENOG4107NGC Flagellar filament outer layer protein FUT81_11225 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FUT81_11245 ENOG4105IJJ transcriptional regulator, crp fnr family FUT81_11250 ENOG4105K63 Thioredoxin FUT81_11255 ENOG41081GK CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl-transferase FUT81_11260 ENOG4105F8V Hydrolase, tatD family FUT81_11270 ENOG4105K6T rare lipoprotein A FUT81_11290 ENOG41090KZ FUT81_11310 ENOG4106UV5 membrane protein A FUT81_11320 ENOG4105CFP Peptidase U32 FUT81_11330 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FUT81_11335 ENOG4107Z25 Basic membrane protein FUT81_11340 ENOG4105M7K Involved in the transcription termination process (By similarity) FUT81_11360 ENOG4105BZA Phosphoglycerate kinase FUT81_11365 ENOG4105CP7 Triose-phosphate isomerase FUT81_11375 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) FUT81_11380 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FUT81_11405 ENOG4105VUF Transcriptional regulator FUT81_11435 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FUT81_11440 ENOG4105D6U Sodium Glutamate Symporter FUT81_11460 ENOG4105WH1 Two component transcriptional regulator luxr family FUT81_11465 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT81_11485 ENOG4105CG6 trap dicarboxylate transporter dctm subunit FUT81_11495 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FUT81_11525 ENOG4107W93 Dihydroorotate dehydrogenase FUT81_11530 ENOG4107XPQ Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FUT81_11540 ENOG4105DVT helicase FUT81_11545 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FUT81_11550 ENOG4105DC7 peptidase M24 FUT81_11560 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FUT81_11570 ENOG4105G3C Type iv pilus assembly FUT81_11600 ENOG4105DVC DnaJ domain protein FUT81_11605 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FUT81_11610 ENOG4105CV1 Transketolase (EC 2.2.1.1) FUT81_11625 ENOG4106TP1 FUT81_11640 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin FUT81_11655 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FUT81_11660 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit FUT81_11665 ENOG4105DGN Electron transport complex FUT81_11670 ENOG4105DZB Electron transport complex FUT81_11680 ENOG4105D6A Electron transport complex FUT81_11685 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) FUT81_11705 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT81_11715 ENOG4105HHA aminodeoxychorismate lyase FUT81_11720 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FUT81_11725 ENOG4107QVY Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT81_11745 ENOG4105DFF Rod shape-determining protein mreb FUT81_11760 ENOG4105CJN penicillin-binding protein FUT81_11765 ENOG4105CNI cell division protein FtsW FUT81_11770 ENOG4105EIB trna rrna methyltransferase FUT81_11780 ENOG4105C3J Cysteine desulfurase FUT81_11795 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) FUT81_11805 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT81_11810 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FUT81_11815 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_11820 ENOG4105E0C molybdate abc transporter FUT81_11825 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FUT81_11835 ENOG4108RIR Molybdenum cofactor biosynthesis protein FUT81_11850 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FUT81_11855 ENOG4105CEV competence damage-inducible protein FUT81_11860 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family FUT81_11865 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding FUT81_11875 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FUT81_11880 ENOG4105BZ8 glutamate synthase FUT81_11885 ENOG4107RCH Diaminopropionate ammonia-lyase FUT81_11890 ENOG4107S4Y M20 DapE family protein YgeY FUT81_11895 ENOG4105IW6 Carbamoyltransferase FUT81_11915 ENOG410908R Methenyltetrahydrofolate cyclohydrolase FUT81_11920 ENOG4105CKU formyltetrahydrofolate synthetase FUT81_11925 ENOG4105CCS Glutamate formiminotransferase FUT81_11930 ENOG4105C84 Histidine ammonia-lyase FUT81_11935 ENOG4105D3Y Na H antiporter FUT81_11945 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FUT81_11950 ENOG4105EEI dihydropteroate synthase FUT81_11955 ENOG4105C8B TIGR00159 family FUT81_11965 ENOG41083V3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FUT81_11970 ENOG4108CER Uncharacterized protein conserved in bacteria (DUF2225) FUT81_11975 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FUT81_11980 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT81_11990 ENOG4105CYC Transferase FUT81_11995 ENOG4105E39 Enoyl-CoA hydratase FUT81_12000 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FUT81_12005 ENOG4105CNW domain protein FUT81_12010 ENOG4105C1G acyl-Coa dehydrogenase FUT81_12015 ENOG4105CHU acetyl-coa acetyltransferase FUT81_12030 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FUT81_12035 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FUT81_12040 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FUT81_12045 ENOG4108IQE Amp-dependent synthetase and ligase FUT81_12050 ENOG4107R5H iron (metal) dependent repressor, dtxr family FUT81_12055 ENOG4107RBD ABC, transporter FUT81_12060 ENOG4107RPQ ABC transporter FUT81_12065 ENOG4105DIK (ABC) transporter FUT81_12070 ENOG4107SIG periplasmic solute binding protein FUT81_12075 ENOG4105C9U ATP-dependent DNA helicase RecQ FUT81_12085 ENOG4107V28 uracil phosphoribosyltransferase FUT81_12155 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) FUT81_12200 ENOG4106TEA FUT81_12235 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FUT81_12240 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FUT81_12255 ENOG4105DFM M18 family aminopeptidase FUT81_12265 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FUT81_12270 ENOG4107I03 FUT81_12295 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FUT81_12305 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_12325 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FUT81_12335 ENOG4108UQV Membrane FUT81_12350 ENOG4105CAH Chromate FUT81_12370 ENOG4106S0F FUT81_12375 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FUT81_12380 ENOG4106GEY FUT81_12390 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FUT81_12400 ENOG4107Z9R response regulator FUT81_12410 ENOG4105YFD chemotaxis, protein FUT81_12415 ENOG4105CBS Chea signal transduction histidine kinase FUT81_12440 ENOG4105F1A Pyruvate formate-lyase FUT81_12445 ENOG4105C6N Formate acetyltransferase FUT81_12455 ENOG4105I03 Flagellin FUT81_12510 ENOG4105DFD Na H antiporter FUT81_12515 ENOG41083HS Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) FUT81_12560 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_12575 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_12585 ENOG4105C3G gtp-binding protein FUT81_12595 ENOG4105VKD bioY protein FUT81_12600 ENOG4108JJB ABC transporter FUT81_12620 ENOG4108HHA Transketolase FUT81_12625 ENOG4108IUS Transketolase FUT81_12630 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FUT81_12655 ENOG4105DQ6 Transposase FUT81_12670 ENOG4105D7X high-affinity nickel-transporter FUT81_12695 ENOG4107TIA phenylalanyl-tRNA synthetase (beta subunit) FUT81_12705 ENOG4105CPF Cell wall formation (By similarity) FUT81_12715 ENOG4105BZ1 (ABC) transporter FUT81_12720 ENOG4105BZ1 (ABC) transporter FUT81_12725 ENOG4105BZ1 (ABC) transporter FUT81_12730 ENOG4105BZ1 (ABC) transporter FUT81_12735 ENOG4108JQ7 (ABC) transporter FUT81_12745 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FUT81_12765 ENOG4105C3M thioredoxin reductase FUT81_12770 ENOG4105D17 glycoside hydrolase, family 3 domain protein FUT81_12790 ENOG4105D3R alkyl hydroperoxide reductase FUT81_12795 ENOG4105E98 transcriptional regulator DeoR family FUT81_12800 ENOG4105DE4 1-phosphofructokinase FUT81_12805 ENOG4105DM4 PTS System FUT81_12810 ENOG4105KZ7 phosphocarrier protein hpr FUT81_12830 ENOG4105MHT Transcriptional regulator, ARSR family FUT81_12840 ENOG4105C59 p-type ATPase FUT81_12850 ENOG4107R3N Filamentation induced by cAMP protein fic FUT81_12865 ENOG4105F2I Transposase FUT81_12915 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_12955 ENOG4105VXP Protein of unknown function DUF86 FUT81_12990 ENOG4105VXP Protein of unknown function DUF86 FUT81_13000 ENOG4105F2I Transposase FUT81_13005 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_13090 ENOG4105CEC DNA methylase N-4 N-6 FUT81_13110 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_13150 ENOG4105F2I Transposase FUT81_13205 ENOG4105C4R Atp-dependent dna helicase FUT81_13220 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FUT81_13230 ENOG4108ZB6 transcriptional regulator AsnC family FUT81_13235 ENOG4105CHM Aminotransferase FUT81_13240 ENOG4105CWM branched-chain amino acid transport system II carrier protein FUT81_13250 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FUT81_13255 ENOG4107QIK phosphoribosylformylglycinamidine synthase FUT81_13260 ENOG4107T2D Phosphoribosylaminoimidazolesuccinocarboxamide synthase FUT81_13270 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FUT81_13275 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FUT81_13280 ENOG4105C6E dna polymerase iii FUT81_13290 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FUT81_13305 ENOG4105JMH Nadph-dependent fmn reductase FUT81_13310 ENOG4105F2I Transposase FUT81_13550 ENOG4105CMR udp-glucose 4-epimerase FUT81_13565 ENOG4105CEP NADH dehydrogenase FUT81_13575 ENOG4105C1G acyl-Coa dehydrogenase FUT81_13580 ENOG4105BZJ Electron transfer flavoprotein FUT81_13585 ENOG4105C10 Electron transfer flavoprotein FUT81_13610 ENOG4105C37 (CBS) domain FUT81_13615 ENOG41082QW Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FUT81_13620 ENOG4105CTJ Metal Dependent Phosphohydrolase FUT81_13625 ENOG4105C9A Phoh family FUT81_13635 ENOG4105C75 arginyL-tRNA synthetase FUT81_13645 ENOG4105CEU Arginine dihydrolase FUT81_13650 ENOG4105DBV ornithine carbamoyltransferase FUT81_13655 ENOG4105C5B carbamate kinase FUT81_13665 ENOG4107QYD Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FUT81_13670 ENOG4105C3S Mate efflux family protein FUT81_13675 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FUT81_13685 ENOG4105VXR cytoplasmic protein FUT81_13700 ENOG4108I5U Uridine phosphorylase FUT81_13715 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FUT81_13720 ENOG4105C87 Aminotransferase class I and II FUT81_13725 ENOG4105CFC Transporter FUT81_13735 ENOG4105DNX Dna topoisomerase iv (Subunit b) FUT81_13745 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FUT81_13755 ENOG4107YY3 extracellular solute-binding protein family 1 FUT81_13765 ENOG4105C9M aspartyl-trna synthetase FUT81_13770 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) FUT81_13775 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FUT81_13790 ENOG4107QX8 SPFH domain, Band 7 family protein FUT81_13810 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FUT81_13825 ENOG4105WH1 Two component transcriptional regulator luxr family FUT81_13830 ENOG4105BZU Histidine kinase FUT81_13840 ENOG4107QP8 phosphohexose isomerase FUT81_13895 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FUT81_13905 ENOG4105CNU cell division protein FtsK FUT81_13910 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FUT81_13915 ENOG4105D82 Glutamate dehydrogenase FUT81_13935 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FUT81_13955 ENOG4105D78 K07001 NTE family protein FUT81_13960 ENOG41085BT Protein of unknown function (DUF1312) FUT81_13980 ENOG4105MB2 FUT81_13985 ENOG4105MB2 FUT81_14005 ENOG4105EI2 Pseudouridine synthase FUT81_14035 ENOG4106VF0 FUT81_14060 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FUT81_14070 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FUT81_14105 ENOG4105E6M Sulphatase-modifying factor protein FUT81_14115 ENOG4109015 Biopolymer transport protein exbD tolR FUT81_14135 ENOG4106DC9 FUT81_14140 ENOG4108ZT0 50S ribosomal protein l17 FUT81_14145 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FUT81_14150 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FUT81_14155 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FUT81_14160 ENOG41067V7 50S ribosomal protein L36 FUT81_14165 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FUT81_14170 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FUT81_14175 ENOG41084HK 50S ribosomal protein L30 FUT81_14180 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FUT81_14185 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FUT81_14190 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FUT81_14195 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FUT81_14200 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FUT81_14205 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FUT81_14210 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) FUT81_14215 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) FUT81_14220 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FUT81_14225 ENOG41086S0 50s ribosomal protein l29 FUT81_14230 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) FUT81_14235 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FUT81_14240 ENOG41082G4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) FUT81_14245 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) FUT81_14250 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FUT81_14255 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) FUT81_14260 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FUT81_14265 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FUT81_14270 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FUT81_14275 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FUT81_14285 ENOG4108I7Y domain protein FUT81_14290 ENOG4105MAX Superoxide reductase FUT81_14295 ENOG4105DCI Phosphohydrolase FUT81_14320 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FUT81_14325 ENOG4105MA4 psp1 domain protein FUT81_14340 ENOG4105DR5 peptidase FUT81_14350 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FUT81_14360 ENOG4105DAP Nicotinate phosphoribosyltransferase FUT81_14375 ENOG4105FZW flagellar biosynthesis regulator FlhF FUT81_14380 ENOG4105D7B Flagellar biosynthesis protein flha FUT81_14385 ENOG4105D00 flagellar biosynthetic protein flhB FUT81_14390 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FUT81_14395 ENOG4105VS8 Flagellar biosynthetic protein fliq FUT81_14400 ENOG4105CN7 Flagellar biosynthetic protein FliP FUT81_14410 ENOG4105DD5 Flagellar motor switch protein FUT81_14415 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FUT81_14420 ENOG41064SM flagellar basal body-associated protein flil FUT81_14425 ENOG4107XSU flagellar motor protein motb FUT81_14430 ENOG4107R0U MotA TolQ exbB proton channel FUT81_14440 ENOG4105BZE flagellar hook protein, FlgE FUT81_14445 ENOG410822I Flagellar hook capping protein FUT81_14470 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FUT81_14480 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FUT81_14495 ENOG4105DPN Oligoendopeptidase f FUT81_14500 ENOG4105E0Y RtcB Protein FUT81_14505 ENOG4105CTS PTS system mannitol-specific FUT81_14510 ENOG4105E98 transcriptional regulator DeoR family FUT81_14515 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein FUT81_14525 ENOG4105FB2 class II Aldolase FUT81_14535 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FUT81_14545 ENOG4105C2M dna polymerase I FUT81_14570 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FUT81_14605 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FUT81_14665 ENOG4105CUZ uba thif-type nad fad binding protein FUT81_14670 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FUT81_14680 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_14685 ENOG4107RCV ABC transporter, permease FUT81_14690 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FUT81_14705 ENOG4105C8Q Methyl-accepting chemotaxis FUT81_14710 ENOG4108V3E phosphoribosylglycinamide formyltransferase FUT81_14715 ENOG4105CXB phosphoribosylaminoimidazole synthetase FUT81_14725 ENOG4105CDY transcriptional regulatory protein FUT81_14735 ENOG4108TVT permease FUT81_14740 ENOG410877G FUT81_14745 ENOG4105RJI FUT81_14765 ENOG4108IQE Amp-dependent synthetase and ligase FUT81_14770 ENOG4105NBF ammecr1 domain protein FUT81_14805 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) FUT81_14810 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FUT81_14830 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FUT81_14850 ENOG4108JJB ABC transporter FUT81_14895 ENOG4105CMT Dihydroxyacetone kinase FUT81_14905 ENOG4105D1H recombination factor protein RarA FUT81_14915 ENOG4105XBK FUT81_14920 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FUT81_14925 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) FUT81_14940 ENOG4107YVC modification (methylase) FUT81_14950 ENOG4105DFA alanine racemase domain protein FUT81_14965 ENOG4107XF7 NGG1p interacting factor 3 protein, NIF3 FUT81_14970 ENOG410835P This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FUT81_14990 ENOG4105DXN mazG family FUT81_14995 ENOG4106XCQ Inherit from COG: Pfam:DUF82 FUT81_15010 ENOG4106FP0 FUT81_15020 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein FUT81_15025 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FUT81_15040 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FUT81_15055 ENOG4105CVS RNA methyltransferase TrmH family, group 1 FUT81_15060 ENOG4108JUB Transcriptional regulator FUT81_15070 ENOG4107XZW Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FUT81_15075 ENOG4105CN1 protease FUT81_15080 ENOG4108Z66 YbaK ebsC protein FUT81_15085 ENOG4105C5H ABC transporter FUT81_15400 ENOG4108Z7G MaoC domain protein dehydratase FUT81_15405 ENOG4108IIG CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) FUT81_15410 ENOG4105CY2 Citrate transporter FUT81_15430 ENOG4105C2J ABC transporter FUT81_15435 ENOG4105CNN ABC, transporter FUT81_15440 ENOG4105CNN ABC, transporter FUT81_15480 ENOG4105DIW FeS assembly protein SUFB FUT81_15490 ENOG4105C9B Cysteine desulfurase FUT81_15495 ENOG4107YH3 SUF system FeS assembly protein, NifU family FUT81_15505 ENOG41088SP formiminoglutamate hydrolase FUT81_15515 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FUT81_15520 ENOG4105HFZ Membrane FUT81_15530 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FUT81_15540 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FUT81_15550 ENOG4108JJB ABC transporter FUT81_15555 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FUT81_15560 ENOG4108IG5 Transcriptional regulator FUT81_15565 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FUT81_15575 ENOG4108UVJ appr-1-p processing domain protein FUT81_15590 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FUT81_15595 ENOG4108UMN azlc family FUT81_15600 ENOG4105KMT branched-chain amino acid