locus-tag	class	description
DYE50_00020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYE50_00025	COG0347	Belongs to the P(II) protein family
DYE50_00060	COG1051	belongs to the nudix hydrolase family
DYE50_00070	COG2382	esterase
DYE50_00070	COG3507	Belongs to the glycosyl hydrolase 43 family
DYE50_00070	COG3693	PFAM glycoside hydrolase, family 10
DYE50_00080	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYE50_00080	COG3443	Belongs to the bacterial solute-binding protein 9 family
DYE50_00085	COG0523	cobalamin synthesis protein
DYE50_00095	COG1304	FMN binding
DYE50_00105	COG0348	domain, Protein
DYE50_00105	COG3901	Regulator of nitric oxide reductase transcription
DYE50_00110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYE50_00130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DYE50_00135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DYE50_00140	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DYE50_00145	COG1904	glucuronate isomerase
DYE50_00150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DYE50_00170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYE50_00185	COG0706	membrane insertase activity
DYE50_00190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DYE50_00215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DYE50_00220	COG0592	DNA-directed DNA polymerase activity
DYE50_00255	COG0187	DNA topoisomerase II activity
DYE50_00260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DYE50_00265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYE50_00280	COG2207	Transcriptional regulator
DYE50_00285	COG0534	Mate efflux family protein
DYE50_00290	COG0515	serine threonine protein kinase
DYE50_00290	COG3266	domain, Protein
DYE50_00300	COG1979	alcohol dehydrogenase
DYE50_00315	COG2203	Gaf domain
DYE50_00315	COG5001	Diguanylate cyclase
DYE50_00315	COG4251	negative regulation of phosphorylation
DYE50_00315	COG3706	GGDEF domain
DYE50_00345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DYE50_00345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYE50_00350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DYE50_00375	COG2217	Heavy metal translocating P-type atpase
DYE50_00380	COG0640	Transcriptional regulator
DYE50_00385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_00390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_00425	COG0488	(ABC) transporter
DYE50_00440	COG0058	SHG alpha-glucan phosphorylase activity
DYE50_00445	COG3706	GGDEF domain
DYE50_00450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYE50_00455	COG2755	lipolytic protein G-D-S-L family
DYE50_00460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYE50_00480	COG1643	Atp-dependent helicase
DYE50_00485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYE50_00515	COG2358	TRAP transporter, solute receptor (TAXI family
DYE50_00525	COG0326	Molecular chaperone. Has ATPase activity
DYE50_00555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYE50_00560	COG3001	Fructosamine kinase
DYE50_00565	COG5001	Diguanylate cyclase
DYE50_00565	COG3300	MHYT domain
DYE50_00570	COG3706	GGDEF domain
DYE50_00575	COG0488	(ABC) transporter
DYE50_00585	COG0281	malic enzyme
DYE50_00610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYE50_00625	COG1674	ftsk spoiiie
DYE50_00630	COG2022	thiamine diphosphate biosynthetic process
DYE50_00645	COG0616	signal peptide processing
DYE50_00680	COG2801	Transposase and inactivated derivatives
DYE50_00695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYE50_00705	COG0668	transmembrane transport
DYE50_00710	COG0534	Mate efflux family protein
DYE50_00730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYE50_00730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYE50_00765	COG0791	NLP P60 protein
DYE50_00765	COG1388	LysM domain
DYE50_00770	COG0246	Mannitol dehydrogenase
DYE50_00775	COG1609	Transcriptional regulator
DYE50_00780	COG4209	transmembrane transport
DYE50_00785	COG0395	ABC-type sugar transport system, permease component
DYE50_00790	COG1653	transport
DYE50_00800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYE50_00825	COG1609	Transcriptional regulator
DYE50_00845	COG4209	transmembrane transport
DYE50_00850	COG0395	ABC-type sugar transport system, permease component
DYE50_00865	COG0442	prolyl-tRNA aminoacylation
DYE50_00885	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_00910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYE50_00930	COG3116	cell division
DYE50_00930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYE50_00935	COG0084	hydrolase, TatD family'
DYE50_00940	COG0739	heme binding
DYE50_00955	COG1774	PSP1 C-terminal conserved region
DYE50_00970	COG2203	Gaf domain
DYE50_00970	COG5001	Diguanylate cyclase
DYE50_00970	COG4251	negative regulation of phosphorylation
DYE50_00970	COG3706	GGDEF domain
DYE50_01025	COG1410	methionine synthase
DYE50_01025	COG0646	methionine synthase
DYE50_01030	COG0574	Belongs to the PEP-utilizing enzyme family
DYE50_01030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYE50_01035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYE50_01050	COG1846	Transcriptional regulator
DYE50_01065	COG0386	Belongs to the glutathione peroxidase family
DYE50_01075	COG0563	adenylate kinase activity
DYE50_01080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYE50_01095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYE50_01100	COG1469	GTP cyclohydrolase I activity
DYE50_01115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DYE50_01120	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYE50_01130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYE50_01185	COG1522	sequence-specific DNA binding
DYE50_01190	COG0436	Aminotransferase
DYE50_01460	COG0602	queuosine metabolic process
DYE50_01465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYE50_01465	COG1328	CTP reductase activity
DYE50_01470	COG2986	histidine ammonia-lyase
DYE50_01485	COG1115	amino acid carrier protein
DYE50_01490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYE50_01500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYE50_01510	COG1283	sodium-dependent phosphate transmembrane transporter activity
DYE50_01525	COG2252	PERMEase
DYE50_01530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DYE50_01540	COG2816	NAD+ diphosphatase activity
DYE50_01570	COG1401	restriction endodeoxyribonuclease activity
DYE50_01595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DYE50_01600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DYE50_01640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DYE50_01880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYE50_01910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYE50_01910	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYE50_01910	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYE50_01910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYE50_01920	COG1396	sequence-specific DNA binding
DYE50_01950	COG1106	Psort location Cytoplasmic, score
DYE50_01990	COG0588	phosphoglycerate mutase activity
DYE50_01995	COG1047	Peptidyl-prolyl cis-trans
DYE50_02005	COG0494	nUDIX hydrolase
DYE50_02040	COG0501	Belongs to the peptidase M48B family
DYE50_02070	COG3300	MHYT domain
DYE50_02070	COG5001	Diguanylate cyclase
DYE50_02075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYE50_02090	COG1032	radical SAM domain protein
DYE50_02105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_02115	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_02120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_02130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DYE50_02135	COG0167	dihydroorotate dehydrogenase activity
DYE50_02155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYE50_02160	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DYE50_02170	COG0824	Thioesterase
DYE50_02190	COG0426	domain, Protein
DYE50_02200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYE50_02210	COG0747	negative chemotaxis
DYE50_02220	COG3437	response regulator, receiver
DYE50_02230	COG0745	RESPONSE REGULATOR receiver
DYE50_02235	COG2205	protein histidine kinase activity
DYE50_02250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYE50_02255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DYE50_02260	COG0455	bacterial-type flagellum organization
DYE50_02265	COG0793	Belongs to the peptidase S41A family
DYE50_02285	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DYE50_02305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYE50_02315	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYE50_02320	COG0475	glutathione-regulated potassium exporter activity
DYE50_02325	COG3842	ATPase activity
DYE50_02345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYE50_02350	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DYE50_02355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYE50_02365	COG0512	Glutamine amidotransferase of anthranilate synthase
DYE50_02365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYE50_02370	COG0366	Alpha amylase catalytic
DYE50_02375	COG0134	indole-3-glycerol-phosphate synthase activity
DYE50_02380	COG0133	tryptophan synthase activity
DYE50_02385	COG0159	tryptophan synthase activity
DYE50_02395	COG0840	transmembrane signaling receptor activity
DYE50_02400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DYE50_02405	COG1045	serine acetyltransferase
DYE50_02415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DYE50_02425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYE50_02430	COG0250	Participates in transcription elongation, termination and antitermination
DYE50_02435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DYE50_02440	COG0081	regulation of translation
DYE50_02445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DYE50_02455	COG0085	RNA polymerase activity
DYE50_02465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYE50_02470	COG0049	tRNA binding
DYE50_02475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYE50_02480	COG0051	transcription antitermination factor activity, RNA binding
DYE50_02485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DYE50_02490	COG0088	Forms part of the polypeptide exit tunnel
DYE50_02495	COG0089	rRNA binding
DYE50_02500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYE50_02505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DYE50_02510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYE50_02515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DYE50_02525	COG0255	Belongs to the universal ribosomal protein uL29 family
DYE50_02530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DYE50_02535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DYE50_02540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DYE50_02545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DYE50_02555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DYE50_02560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DYE50_02565	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DYE50_02570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DYE50_02580	COG0200	Binds to the 23S rRNA
DYE50_02590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYE50_02600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DYE50_02605	COG0202	RNA polymerase activity
DYE50_02610	COG0203	ribosomal protein L17
DYE50_02675	COG2801	Transposase and inactivated derivatives
DYE50_02775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DYE50_02785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_02785	COG2199	diguanylate cyclase activity
DYE50_02790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYE50_02795	COG2755	lipolytic protein G-D-S-L family
DYE50_02805	COG2839	Protein conserved in bacteria
DYE50_02815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYE50_02825	COG3842	ATPase activity
DYE50_02830	COG4120	Belongs to the binding-protein-dependent transport system permease family
DYE50_02835	COG2208	phosphoserine phosphatase activity
DYE50_02835	COG2770	Histidine kinase
DYE50_02860	COG2208	phosphoserine phosphatase activity
DYE50_02860	COG2770	Histidine kinase
DYE50_02870	COG1366	Belongs to the anti-sigma-factor antagonist family
DYE50_02880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DYE50_02885	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DYE50_02890	COG0733	neurotransmitter:sodium symporter activity
DYE50_02940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYE50_02945	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DYE50_02955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYE50_02960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYE50_02980	COG2197	response regulator
DYE50_03000	COG0745	RESPONSE REGULATOR receiver
DYE50_03005	COG2205	protein histidine kinase activity
DYE50_03005	COG3437	response regulator, receiver
DYE50_03005	COG4999	Histidine kinase
DYE50_03005	COG3850	Histidine kinase
DYE50_03015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYE50_03020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DYE50_03025	COG0484	heat shock protein binding
DYE50_03065	COG0714	Associated with various cellular activities
DYE50_03095	COG0534	Mate efflux family protein
DYE50_03100	COG0012	GTP binding
DYE50_03110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYE50_03130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYE50_03130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYE50_03130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYE50_03165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYE50_03170	COG1242	4 iron, 4 sulfur cluster binding
DYE50_03180	COG0653	protein targeting
DYE50_03195	COG0564	pseudouridine synthase activity
DYE50_03210	COG5001	Diguanylate cyclase
DYE50_03210	COG3300	MHYT domain
DYE50_03215	COG1086	Polysaccharide biosynthesis protein
DYE50_03220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYE50_03240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYE50_03250	COG2255	four-way junction helicase activity
DYE50_03255	COG0632	four-way junction helicase activity
DYE50_03295	COG0534	Mate efflux family protein
DYE50_03320	COG3330	Domain of unknown function (DUF4912)
DYE50_03355	COG2001	Belongs to the MraZ family
DYE50_03360	COG0275	rRNA processing
DYE50_03370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYE50_03375	COG0772	Belongs to the SEDS family
DYE50_03380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DYE50_03395	COG4974	Belongs to the 'phage' integrase family
DYE50_03410	COG0551	DNA topoisomerase type I activity
DYE50_03410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYE50_03415	COG4974	Belongs to the 'phage' integrase family
DYE50_03420	COG0840	transmembrane signaling receptor activity
DYE50_03425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DYE50_03430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DYE50_03440	COG3706	GGDEF domain
DYE50_03455	COG3706	GGDEF domain
DYE50_03460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DYE50_03470	COG0028	Belongs to the TPP enzyme family
DYE50_03475	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_03480	COG3876	Protein conserved in bacteria
DYE50_03495	COG0191	fructose-bisphosphate aldolase activity
DYE50_03510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_03530	COG0779	Required for maturation of 30S ribosomal subunits
DYE50_03540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYE50_03545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYE50_03560	COG0367	asparagine synthase
DYE50_03565	COG0504	CTP synthase activity
DYE50_03585	COG0534	Mate efflux family protein
DYE50_03610	COG0493	'glutamate synthase
DYE50_03615	COG0067	glutamate synthase
DYE50_03615	COG0070	glutamate synthase
DYE50_03615	COG0069	glutamate synthase activity
DYE50_03650	COG0004	ammonium transporteR
DYE50_03655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYE50_03660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DYE50_03665	COG1185	polyribonucleotide nucleotidyltransferase activity
DYE50_03670	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DYE50_03685	COG1609	Transcriptional regulator
DYE50_03695	COG1175	transmembrane transport
DYE50_03700	COG3833	ABC-type maltose transport systems, permease component
DYE50_03710	COG0756	dUTP diphosphatase activity
DYE50_03725	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_03730	COG0343	queuine tRNA-ribosyltransferase activity
DYE50_03750	COG2770	Histidine kinase
DYE50_03750	COG2208	phosphoserine phosphatase activity
DYE50_03805	COG1397	ADP-ribosylglycohydrolase
DYE50_03840	COG2089	acid synthase
DYE50_03855	COG0217	transcriptional regulatory protein
DYE50_03880	COG1362	aminopeptidase activity
DYE50_03885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYE50_03890	COG0740	serine-type endopeptidase activity
DYE50_03895	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYE50_03945	COG2199	diguanylate cyclase activity
DYE50_03955	COG2409	Drug exporters of the RND superfamily
DYE50_03955	COG1033	growth of symbiont in host cell
DYE50_03975	COG2375	cellular response to nickel ion
DYE50_03975	COG1132	(ABC) transporter
DYE50_04000	COG1309	transcriptional regulator
DYE50_04010	COG2217	Heavy metal translocating P-type atpase
DYE50_04020	COG0148	phosphopyruvate hydratase activity
DYE50_04035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DYE50_04040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DYE50_04045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DYE50_04050	COG1214	PFAM Peptidase M22, glycoprotease
DYE50_04055	COG0802	atpase or kinase
DYE50_04095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYE50_04120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYE50_04130	COG1473	amidohydrolase
DYE50_04135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYE50_04140	COG2011	ABC-type metal ion transport system permease component
DYE50_04150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYE50_04175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYE50_04180	COG1464	Belongs to the NlpA lipoprotein family
DYE50_04185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYE50_04190	COG1464	Belongs to the NlpA lipoprotein family
DYE50_04195	COG0277	FAD linked oxidase domain protein
DYE50_04200	COG0436	Aminotransferase
DYE50_04215	COG0765	amino acid transport
DYE50_04220	COG0765	amino acid transport
DYE50_04235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DYE50_04245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYE50_04260	COG1268	BioY protein
DYE50_04265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DYE50_04270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DYE50_04275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYE50_04300	COG0419	ATPase involved in DNA repair
DYE50_04305	COG1301	dicarboxylic acid transport
DYE50_04320	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DYE50_04330	COG0739	heme binding
DYE50_04340	COG1716	ATPase activity
DYE50_04340	COG1131	(ABC) transporter
DYE50_04340	COG0842	Transport permease protein
DYE50_04360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_04365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYE50_04370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYE50_04380	COG0084	hydrolase, TatD family'
DYE50_04385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DYE50_04395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYE50_04395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DYE50_04405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYE50_04415	COG1104	cysteine desulfurase activity
DYE50_04420	COG0731	radical SAM domain protein
DYE50_04440	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYE50_04460	COG1199	ATP-dependent helicase activity
DYE50_04475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYE50_04490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYE50_04505	COG3852	Histidine kinase
DYE50_04510	COG2204	response regulator
DYE50_04520	COG0268	Binds directly to 16S ribosomal RNA
DYE50_04530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DYE50_04540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DYE50_04550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYE50_04570	COG0438	transferase activity, transferring glycosyl groups
DYE50_04585	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DYE50_04585	COG0028	Belongs to the TPP enzyme family
DYE50_04600	COG0706	membrane insertase activity
DYE50_04605	COG0706	membrane insertase activity
DYE50_04610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DYE50_04625	COG0706	membrane insertase activity
DYE50_04630	COG0706	membrane insertase activity
DYE50_04700	COG0706	membrane insertase activity
DYE50_04710	COG1216	Glycosyl transferase, family 2
DYE50_04750	COG1136	(ABC) transporter
DYE50_04770	COG1091	dTDP-4-dehydrorhamnose reductase activity
DYE50_04785	COG0658	competence protein
DYE50_04785	COG2333	competence protein COMEC
DYE50_04790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYE50_04805	COG0564	pseudouridine synthase activity
DYE50_04815	COG0436	Aminotransferase
DYE50_04820	COG0297	glycogen (starch) synthase activity
DYE50_04825	COG0360	Binds together with S18 to 16S ribosomal RNA
DYE50_04830	COG0629	single-stranded DNA binding
DYE50_04835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DYE50_04840	COG0359	binds to the 23S rRNA
DYE50_04845	COG0305	Participates in initiation and elongation during chromosome replication
DYE50_04860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYE50_04870	COG0617	tRNA 3'-terminal CCA addition
DYE50_04875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DYE50_04885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYE50_04885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYE50_04895	COG0735	belongs to the Fur family
DYE50_04900	COG1592	Rubrerythrin
DYE50_04910	COG1234	tRNA 3'-trailer cleavage
DYE50_04920	COG3177	Filamentation induced by cAMP protein fic
DYE50_04930	COG0732	type I restriction modification DNA specificity domain
DYE50_04930	COG0732	type I restriction modification DNA specificity domain
DYE50_04965	COG4555	ABC transporter
DYE50_04985	COG0066	3-isopropylmalate dehydratase activity
DYE50_04990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYE50_04995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYE50_05035	COG0750	zinc metalloprotease
DYE50_05040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYE50_05045	COG0575	Belongs to the CDS family
DYE50_05050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYE50_05055	COG0233	cytoplasmic translational termination
DYE50_05060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYE50_05065	COG0052	Belongs to the universal ribosomal protein uS2 family
DYE50_05070	COG0424	maF-like protein
DYE50_05075	COG1413	lyase activity
DYE50_05085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DYE50_05090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DYE50_05100	COG0571	ribonuclease III activity
DYE50_05105	COG0254	rRNA binding
DYE50_05120	COG0513	Belongs to the DEAD box helicase family
DYE50_05125	COG0488	(ABC) transporter
DYE50_05130	COG0784	Response regulator, receiver
DYE50_05130	COG2205	protein histidine kinase activity
DYE50_05130	COG2198	Histidine kinase
DYE50_05140	COG2801	Transposase and inactivated derivatives
DYE50_05155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYE50_05195	COG1690	Belongs to the RtcB family
DYE50_05215	COG3541	Predicted nucleotidyltransferase
DYE50_05245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_05335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_05370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_05375	COG3386	PFAM SMP-30 Gluconolaconase
DYE50_05385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_05405	COG3191	aminopeptidase activity
DYE50_05410	COG1937	Protein conserved in bacteria
DYE50_05435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYE50_05440	COG3177	Filamentation induced by cAMP protein fic
DYE50_05465	COG2770	Histidine kinase
DYE50_05465	COG2208	phosphoserine phosphatase activity
DYE50_05475	COG2315	Protein conserved in bacteria
DYE50_05490	COG2226	methyltransferase
DYE50_05565	COG0442	prolyl-tRNA aminoacylation
DYE50_05585	COG0454	-acetyltransferase
DYE50_05605	COG0251	oxidation-reduction process
DYE50_05630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYE50_05655	COG3300	MHYT domain
DYE50_05655	COG5001	Diguanylate cyclase
DYE50_05665	COG0784	Response regulator, receiver
DYE50_05665	COG2205	protein histidine kinase activity
DYE50_05695	COG0840	transmembrane signaling receptor activity
DYE50_05715	COG0596	Alpha beta hydrolase
DYE50_05735	COG1105	Belongs to the carbohydrate kinase PfkB family
DYE50_05815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_05845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DYE50_05850	COG0259	pyridoxamine-phosphate oxidase activity
DYE50_05855	COG2207	Transcriptional regulator
DYE50_05880	COG2378	regulation of single-species biofilm formation
DYE50_05885	COG0693	protein deglycase activity
DYE50_05910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYE50_05935	COG0456	acetyltransferase
DYE50_05955	COG0456	acetyltransferase
DYE50_05975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_05985	COG4978	Transcriptional regulator
DYE50_05985	COG0789	Transcriptional regulator
DYE50_06000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYE50_06025	COG0534	Mate efflux family protein
DYE50_06070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYE50_06075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DYE50_06105	COG0110	maltose O-acetyltransferase activity
DYE50_06115	COG0519	Catalyzes the synthesis of GMP from XMP
DYE50_06120	COG2746	aminoglycoside 3-N-acetyltransferase activity
DYE50_06145	COG1192	Involved in chromosome partitioning
DYE50_06155	COG1794	racemase activity, acting on amino acids and derivatives
DYE50_06200	COG1687	branched-chain amino acid
DYE50_06205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DYE50_06210	COG0561	phosphatase activity
DYE50_06220	COG1011	Hydrolase
DYE50_06285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYE50_06295	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYE50_06305	COG2244	polysaccharide biosynthetic process
DYE50_06340	COG1442	glycosyl transferase family 8
DYE50_06360	COG1482	cell wall glycoprotein biosynthetic process
DYE50_06395	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DYE50_06425	COG1397	ADP-ribosylglycohydrolase
DYE50_06445	COG1401	restriction endodeoxyribonuclease activity
DYE50_06485	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DYE50_06490	COG3421	Type III restriction
DYE50_06565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_06615	COG2801	Transposase and inactivated derivatives
DYE50_06625	COG0772	Belongs to the SEDS family
DYE50_06630	COG0768	penicillin binding
DYE50_06645	COG1077	Cell shape determining protein MreB Mrl
DYE50_06665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYE50_06670	COG0358	DNA primase activity
DYE50_06730	COG1102	Psort location Cytoplasmic, score
DYE50_06735	COG1561	YicC-like family, N-terminal region
DYE50_06740	COG0180	Tryptophanyl-tRNA synthetase
DYE50_06745	COG0590	tRNA wobble adenosine to inosine editing
DYE50_06750	COG0285	dihydrofolate synthase activity
DYE50_06755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYE50_06765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYE50_06775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_06810	COG1269	ATP hydrolysis coupled proton transport
DYE50_06815	COG1394	ATPase activity, coupled to movement of substances
DYE50_06820	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DYE50_06825	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DYE50_06835	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DYE50_06895	COG4656	Part of a membrane complex involved in electron transport
DYE50_06935	COG0028	Belongs to the TPP enzyme family
DYE50_06950	COG0681	Belongs to the peptidase S26 family
DYE50_06970	COG2116	formate transmembrane transporter activity
DYE50_06975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYE50_07025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYE50_07030	COG1450	Type ii and iii secretion system protein
DYE50_07045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYE50_07055	COG1653	transport
DYE50_07130	COG1196	nuclear chromosome segregation
DYE50_07150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYE50_07160	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DYE50_07170	COG0733	neurotransmitter:sodium symporter activity
DYE50_07180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYE50_07185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYE50_07205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_07215	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYE50_07245	COG0564	pseudouridine synthase activity
DYE50_07255	COG4786	Flagellar basal body rod
DYE50_07260	COG1716	ATPase activity
DYE50_07260	COG5001	Diguanylate cyclase
DYE50_07265	COG0124	histidyl-tRNA synthetase
DYE50_07285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYE50_07290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DYE50_07305	COG0640	Transcriptional regulator
DYE50_07320	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DYE50_07325	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYE50_07330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DYE50_07335	COG2373	Large extracellular alpha-helical protein
DYE50_07370	COG1846	Transcriptional regulator
DYE50_07375	COG4974	Belongs to the 'phage' integrase family
DYE50_07400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DYE50_07405	COG0542	response to heat
DYE50_07410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYE50_07445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYE50_07465	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DYE50_07505	COG1136	(ABC) transporter
DYE50_07510	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYE50_07520	COG0552	protein localization to endoplasmic reticulum
DYE50_07555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DYE50_07560	COG1480	7TM receptor with intracellular HD hydrolase
DYE50_07565	COG1702	phosphate starvation-inducible protein PhoH
DYE50_07580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYE50_07585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYE50_07590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DYE50_07615	COG1191	sigma factor activity
DYE50_07625	COG0455	bacterial-type flagellum organization
DYE50_07630	COG1419	protein localization to endoplasmic reticulum
DYE50_07635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_07640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_07645	COG1684	flagellar biosynthetic protein fliR
DYE50_07650	COG1987	bacterial-type flagellum assembly
DYE50_07655	COG1338	Plays a role in the flagellum-specific transport system
DYE50_07670	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_07675	COG1580	Controls the rotational direction of flagella during chemotaxis
DYE50_07680	COG1360	Flagellar Motor Protein
DYE50_07690	COG1582	Flagellar protein (FlbD)
DYE50_07695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYE50_07705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DYE50_07715	COG0009	L-threonylcarbamoyladenylate synthase
DYE50_07760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYE50_07765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYE50_07775	COG1022	Amp-dependent synthetase and ligase
DYE50_07790	COG0170	dolichyl monophosphate biosynthetic process
DYE50_07805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYE50_07810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DYE50_07815	COG0105	UTP biosynthetic process
DYE50_07820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DYE50_07830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYE50_07835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYE50_07840	COG1862	Preprotein translocase
DYE50_07860	COG0741	lytic transglycosylase activity
DYE50_07860	COG1388	LysM domain
DYE50_07875	COG0436	Aminotransferase
DYE50_07880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYE50_07885	COG2211	Major facilitator Superfamily
DYE50_07890	COG1309	transcriptional regulator
DYE50_07920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DYE50_07970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYE50_07985	COG0826	peptidase U32
DYE50_07995	COG0301	tRNA thio-modification
DYE50_08015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYE50_08020	COG1573	uracil-dna glycosylase
DYE50_08025	COG0101	tRNA pseudouridine synthase activity
DYE50_08035	COG0736	holo-[acyl-carrier-protein] synthase activity
DYE50_08050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYE50_08055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYE50_08070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYE50_08070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DYE50_08075	COG5001	Diguanylate cyclase
DYE50_08080	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DYE50_08090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYE50_08105	COG0741	lytic transglycosylase activity
DYE50_08105	COG0739	heme binding
DYE50_08105	COG1196	nuclear chromosome segregation
DYE50_08150	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DYE50_08170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DYE50_08175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DYE50_08180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYE50_08185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYE50_08205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYE50_08215	COG1747	RNA polymerase binding
DYE50_08215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYE50_08245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYE50_08260	COG4120	Belongs to the binding-protein-dependent transport system permease family
DYE50_08270	COG2199	diguanylate cyclase activity
DYE50_08275	COG1475	DNA binding
DYE50_08280	COG1192	Involved in chromosome partitioning
DYE50_08290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYE50_08305	COG2801	Transposase and inactivated derivatives
DYE50_08335	COG0423	glycine-tRNA ligase activity
DYE50_08345	COG2199	diguanylate cyclase activity
DYE50_08345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_08355	COG2604	Protein of unknown function DUF115
DYE50_08370	COG0741	lytic transglycosylase activity
DYE50_08370	COG1196	nuclear chromosome segregation
DYE50_08370	COG0739	heme binding
DYE50_08380	COG0726	polysaccharide deacetylase
DYE50_08385	COG2755	lipolytic protein G-D-S-L family
DYE50_08395	COG1686	Belongs to the peptidase S11 family
DYE50_08400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYE50_08405	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_08410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_08425	COG0765	amino acid transport
DYE50_08430	COG1126	abc transporter atp-binding protein
DYE50_08465	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DYE50_08470	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DYE50_08480	COG0826	peptidase U32
DYE50_08540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYE50_08560	COG0697	spore germination
DYE50_08565	COG0564	pseudouridine synthase activity
DYE50_08575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYE50_08580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DYE50_08585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYE50_08590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYE50_08600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYE50_08605	COG0737	Belongs to the 5'-nucleotidase family
DYE50_08610	COG0626	cystathionine gamma-synthase activity
DYE50_08615	COG1959	2 iron, 2 sulfur cluster binding
DYE50_08625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYE50_08635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DYE50_08645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYE50_08665	COG1187	pseudouridine synthase activity
DYE50_08670	COG0372	Belongs to the citrate synthase family
DYE50_08680	COG2502	aspartate--ammonia ligase
DYE50_08705	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DYE50_08735	COG1984	allophanate hydrolase subunit 2
DYE50_08740	COG4336	lyase activity
DYE50_08755	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_08765	COG1175	transmembrane transport
DYE50_08770	COG3833	ABC-type maltose transport systems, permease component
DYE50_08790	COG0126	phosphoglycerate kinase activity
DYE50_08795	COG0149	triose-phosphate isomerase activity
DYE50_08805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_08805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYE50_08805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_08820	COG1269	ATP hydrolysis coupled proton transport
DYE50_08840	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DYE50_08845	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DYE50_08850	COG1394	ATPase activity, coupled to movement of substances
DYE50_08855	COG0589	response to stress
DYE50_08860	COG1609	Transcriptional regulator
DYE50_08865	COG1653	transport
DYE50_08870	COG1175	transmembrane transport
DYE50_08875	COG0395	ABC-type sugar transport system, permease component
DYE50_08890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYE50_08910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DYE50_08915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYE50_08925	COG2201	protein-glutamate methylesterase activity
DYE50_08930	COG3845	ABC transporter
DYE50_08950	COG1592	Rubrerythrin
DYE50_08955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DYE50_08995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DYE50_09015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYE50_09025	COG5001	Diguanylate cyclase
DYE50_09030	COG2205	protein histidine kinase activity
DYE50_09030	COG0784	Response regulator, receiver
DYE50_09030	COG5002	protein histidine kinase activity
DYE50_09055	COG3842	ATPase activity
DYE50_09060	COG0557	exoribonuclease II activity
DYE50_09065	COG0484	heat shock protein binding
DYE50_09070	COG0024	Methionine aminopeptidase
DYE50_09080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DYE50_09090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DYE50_09095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYE50_09115	COG0799	negative regulation of ribosome biogenesis
DYE50_09125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DYE50_09140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYE50_09145	COG0037	tRNA processing
DYE50_09150	COG0457	Tetratricopeptide repeat
DYE50_09155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYE50_09160	COG0481	GTPase activity
DYE50_09165	COG2604	Protein of unknown function DUF115
DYE50_09180	COG4977	sequence-specific DNA binding
DYE50_09180	COG1917	Cupin 2, conserved barrel domain protein
DYE50_09185	COG0366	Alpha amylase catalytic
DYE50_09190	COG3833	ABC-type maltose transport systems, permease component
DYE50_09195	COG1175	transmembrane transport
DYE50_09200	COG2182	Extracellular solute-binding protein
DYE50_09215	COG0366	Alpha amylase catalytic
DYE50_09215	COG1874	Beta-galactosidase
DYE50_09220	COG1523	belongs to the glycosyl hydrolase 13 family
DYE50_09225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYE50_09240	COG0473	3-isopropylmalate dehydrogenase activity
DYE50_09255	COG1175	transmembrane transport
DYE50_09260	COG0395	ABC-type sugar transport system, permease component
DYE50_09265	COG3507	Belongs to the glycosyl hydrolase 43 family
DYE50_09270	COG1609	Transcriptional regulator
DYE50_09275	COG1070	Carbohydrate kinase
DYE50_09295	COG0659	secondary active sulfate transmembrane transporter activity
DYE50_09300	COG1234	tRNA 3'-trailer cleavage
DYE50_09305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYE50_09330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYE50_09335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYE50_09365	COG0017	Asparaginyl-tRNA synthetase
DYE50_09370	COG2358	TRAP transporter, solute receptor (TAXI family
DYE50_09385	COG0142	geranyltranstransferase activity
DYE50_09410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_09420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYE50_09430	COG1640	4-alpha-glucanotransferase
DYE50_09435	COG2059	Chromate
DYE50_09445	COG0813	purine-nucleoside phosphorylase activity
DYE50_09455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYE50_09460	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DYE50_09465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DYE50_09470	COG0156	8-amino-7-oxononanoate synthase activity
DYE50_09475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DYE50_09490	COG1482	cell wall glycoprotein biosynthetic process
DYE50_09500	COG5001	Diguanylate cyclase
DYE50_09500	COG1716	ATPase activity
DYE50_09515	COG0588	phosphoglycerate mutase activity
DYE50_09595	COG0747	negative chemotaxis
DYE50_09600	COG0204	Acyl-transferase
DYE50_09605	COG0601	transmembrane transport
DYE50_09610	COG0444	Belongs to the ABC transporter superfamily
DYE50_09615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYE50_09650	COG2201	protein-glutamate methylesterase activity
DYE50_09660	COG2198	Histidine kinase
DYE50_09660	COG0784	Response regulator, receiver
DYE50_09660	COG0643	Histidine kinase
DYE50_09670	COG4608	Belongs to the ABC transporter superfamily
DYE50_09675	COG1757	Na H antiporter
DYE50_09685	COG0564	pseudouridine synthase activity
DYE50_09715	COG1366	Belongs to the anti-sigma-factor antagonist family
DYE50_09730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYE50_09745	COG1837	Belongs to the UPF0109 family
DYE50_09750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYE50_09755	COG0336	Belongs to the RNA methyltransferase TrmD family
DYE50_09760	COG0335	large ribosomal subunit rRNA binding
DYE50_09770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_09780	COG0792	nuclease activity
DYE50_09805	COG0084	hydrolase, TatD family'
DYE50_09810	COG0166	Belongs to the GPI family
DYE50_09815	COG0822	iron-sulfur transferase activity
DYE50_09820	COG5002	protein histidine kinase activity
DYE50_09825	COG0745	RESPONSE REGULATOR receiver
DYE50_09840	COG0396	ATPase activity
DYE50_09845	COG0719	Fe-S assembly protein
DYE50_09850	COG0719	Fe-S assembly protein
DYE50_09860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYE50_09870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DYE50_09880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYE50_09890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYE50_09900	COG0493	'glutamate synthase
DYE50_09905	COG0835	chemotaxis
DYE50_09915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYE50_09920	COG0497	DNA recombination
DYE50_09935	COG1388	LysM domain
DYE50_09935	COG3942	CHAP domain
DYE50_09950	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYE50_09960	COG3437	response regulator, receiver
DYE50_09960	COG2770	Histidine kinase
DYE50_09965	COG1671	Belongs to the UPF0178 family
DYE50_09970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DYE50_10000	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_10010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DYE50_10025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYE50_10055	COG1193	negative regulation of DNA recombination
DYE50_10060	COG0572	uridine kinase
DYE50_10065	COG1438	arginine binding
DYE50_10075	COG1157	protein secretion by the type III secretion system
DYE50_10080	COG1317	bacterial-type flagellum organization
DYE50_10085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_10090	COG1766	The M ring may be actively involved in energy transduction
DYE50_10095	COG1677	Flagellar hook-basal body complex protein FliE
DYE50_10110	COG1126	abc transporter atp-binding protein
DYE50_10115	COG0765	amino acid transport
DYE50_10120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_10130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYE50_10160	COG0542	response to heat
DYE50_10165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DYE50_10170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DYE50_10175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYE50_10180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYE50_10185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYE50_10195	COG0018	arginyl-trna synthetase
DYE50_10200	COG0622	Phosphoesterase
DYE50_10205	COG2357	RelA SpoT domain protein
DYE50_10210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYE50_10215	COG0720	synthase
DYE50_10220	COG2201	protein-glutamate methylesterase activity
DYE50_10230	COG0835	chemotaxis
DYE50_10235	COG2198	Histidine kinase
DYE50_10235	COG0643	Histidine kinase
DYE50_10240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYE50_10250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DYE50_10255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DYE50_10260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DYE50_10280	COG1477	protein flavinylation
DYE50_10290	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYE50_10300	COG4213	ABC transporter substrate-binding protein
DYE50_10305	COG4213	ABC transporter substrate-binding protein
DYE50_10310	COG2207	Transcriptional regulator
DYE50_10315	COG2972	Histidine kinase
DYE50_10325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DYE50_10345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DYE50_10355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYE50_10380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DYE50_10385	COG0154	amidase activity
DYE50_10425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYE50_10440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYE50_10445	COG1516	flagellar protein fliS
DYE50_10485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYE50_10500	COG1595	DNA-templated transcription, initiation
DYE50_10510	COG1196	nuclear chromosome segregation
DYE50_10510	COG0741	lytic transglycosylase activity
DYE50_10510	COG0739	heme binding
DYE50_10515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DYE50_10520	COG1418	mRNA catabolic process
DYE50_10525	COG1137	ATPase activity
DYE50_10545	COG2201	protein-glutamate methylesterase activity
DYE50_10550	COG0523	cobalamin synthesis protein
DYE50_10570	COG1131	(ABC) transporter
DYE50_10600	COG1395	domain, Protein
DYE50_10625	COG2199	diguanylate cyclase activity
DYE50_10640	COG1739	Uncharacterized protein family UPF0029
DYE50_10655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYE50_10670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYE50_10675	COG1597	lipid kinase activity
DYE50_10690	COG1876	peptidase activity
DYE50_10710	COG0724	RNA recognition motif
DYE50_10715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYE50_10720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYE50_10740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DYE50_10775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DYE50_10780	COG0215	cysteine-tRNA ligase activity
DYE50_10795	COG1305	Transglutaminase-like
DYE50_10800	COG0528	UMP kinase activity
DYE50_10815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYE50_10815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_10815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_10830	COG1640	4-alpha-glucanotransferase
DYE50_10840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYE50_10850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_10855	COG1653	transport
DYE50_10860	COG2873	o-acetylhomoserine
DYE50_10865	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DYE50_10875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DYE50_10885	COG5001	Diguanylate cyclase
DYE50_10885	COG3300	MHYT domain
DYE50_10900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYE50_10910	COG0138	bifunctional purine biosynthesis protein purh
DYE50_10925	COG4555	ABC transporter
DYE50_10930	COG2207	Transcriptional regulator
DYE50_10930	COG1917	Cupin 2, conserved barrel domain protein
DYE50_10940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYE50_10955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DYE50_10960	COG1879	ABC-type sugar transport system periplasmic component
DYE50_10975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYE50_10985	COG1136	(ABC) transporter
DYE50_11015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYE50_11035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DYE50_11050	COG1116	anion transmembrane transporter activity
DYE50_11080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYE50_11095	COG1126	abc transporter atp-binding protein
DYE50_11100	COG0765	amino acid transport
DYE50_11105	COG0765	amino acid transport
DYE50_11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_11115	COG0583	DNA-binding transcription factor activity
DYE50_11120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DYE50_11140	COG0386	Belongs to the glutathione peroxidase family
DYE50_11150	COG1979	alcohol dehydrogenase
DYE50_11155	COG2816	NAD+ diphosphatase activity
DYE50_11185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYE50_11210	COG0811	peptide transport
DYE50_11240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYE50_11245	COG0800	Aldolase
DYE50_11250	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_11280	COG0495	leucyl-tRNA aminoacylation
DYE50_11310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYE50_11330	COG2770	Histidine kinase
DYE50_11330	COG2208	phosphoserine phosphatase activity
DYE50_11350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYE50_11395	COG0556	nucleotide-excision repair
DYE50_11440	COG3250	beta-galactosidase activity
DYE50_11450	COG0527	aspartate kinase activity
DYE50_11450	COG0460	homoserine dehydrogenase
DYE50_11480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYE50_11485	COG3706	GGDEF domain
DYE50_11510	COG3706	GGDEF domain
DYE50_11520	COG1523	belongs to the glycosyl hydrolase 13 family
DYE50_11525	COG0366	Alpha amylase catalytic
DYE50_11535	COG1874	Beta-galactosidase
DYE50_11535	COG0366	Alpha amylase catalytic
DYE50_11545	COG0525	valine-tRNA ligase activity
DYE50_11555	COG5001	Diguanylate cyclase
DYE50_11555	COG3300	MHYT domain
DYE50_11560	COG0137	argininosuccinate synthase activity
DYE50_11585	COG0745	RESPONSE REGULATOR receiver
DYE50_11595	COG1660	Displays ATPase and GTPase activities
DYE50_11600	COG1454	alcohol dehydrogenase
DYE50_11600	COG1012	belongs to the aldehyde dehydrogenase family
DYE50_11615	COG0484	heat shock protein binding
DYE50_11620	COG0443	Heat shock 70 kDa protein
DYE50_11625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYE50_11630	COG0440	acetolactate synthase activity
DYE50_11645	COG1183	phosphatidylcholine synthase activity
DYE50_11650	COG0688	phosphatidylethanolamine metabolic process
DYE50_11670	COG4584	PFAM Integrase catalytic
DYE50_11700	COG2003	Belongs to the UPF0758 family
DYE50_11725	COG4962	Type ii secretion system protein e
DYE50_11745	COG3451	type IV secretory pathway VirB4
DYE50_11820	COG0582	viral genome integration into host DNA
DYE50_11840	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DYE50_11865	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYE50_11865	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYE50_11880	COG1733	regulation of RNA biosynthetic process
DYE50_11915	COG1132	(ABC) transporter
DYE50_11925	COG1309	transcriptional regulator
DYE50_11935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYE50_11945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYE50_11950	COG0129	dihydroxy-acid dehydratase activity
DYE50_11955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYE50_11990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DYE50_12005	COG3759	membrane
DYE50_12015	COG1737	Transcriptional regulator
DYE50_12025	COG1177	transmembrane transport
DYE50_12030	COG3842	ATPase activity
DYE50_12045	COG2207	Transcriptional regulator
DYE50_12045	COG4753	response regulator
DYE50_12050	COG2972	Histidine kinase
DYE50_12055	COG0395	ABC-type sugar transport system, permease component
DYE50_12060	COG1175	transmembrane transport
DYE50_12075	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYE50_12120	COG3443	Belongs to the bacterial solute-binding protein 9 family
DYE50_12120	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYE50_12125	COG1121	(ABC) transporter
DYE50_12130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYE50_12145	COG3706	GGDEF domain
DYE50_12160	COG1111	helicase
DYE50_12160	COG1205	dead DEAH box helicase
DYE50_12165	COG4209	transmembrane transport
DYE50_12170	COG0395	ABC-type sugar transport system, permease component
DYE50_12175	COG1653	transport
DYE50_12200	COG4209	transmembrane transport
DYE50_12205	COG0395	ABC-type sugar transport system, permease component
DYE50_12210	COG1653	transport
DYE50_12215	COG3119	arylsulfatase activity
DYE50_12220	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYE50_12340	COG0037	tRNA processing
DYE50_12345	COG5505	Protein of unknown function (DUF819)
DYE50_12355	COG0640	Transcriptional regulator
DYE50_12360	COG2217	Heavy metal translocating P-type atpase
DYE50_12365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYE50_12370	COG1418	mRNA catabolic process
DYE50_12405	COG0640	Transcriptional regulator
DYE50_12425	COG0534	Mate efflux family protein
DYE50_12430	COG0534	Mate efflux family protein
DYE50_12435	COG0534	Mate efflux family protein
DYE50_12440	COG0527	aspartate kinase activity
DYE50_12450	COG3842	ATPase activity
DYE50_12455	COG1854	S-ribosylhomocysteine lyase activity
DYE50_12460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYE50_12475	COG0583	DNA-binding transcription factor activity
DYE50_12490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_12515	COG0579	oxidoreductase
DYE50_12520	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYE50_12615	COG0534	Mate efflux family protein