locus-tag	class	description
Tresu_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Tresu_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Tresu_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Tresu_0005	ENOG4105VG0	50S ribosomal protein l34
Tresu_0006	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Tresu_0007	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Tresu_0008	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Tresu_0010	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Tresu_0012	ENOG4105VVB	
Tresu_0014	ENOG4105KG3	cytidine deaminase
Tresu_0015	ENOG4105HBR	Rna-binding protein
Tresu_0019	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Tresu_0022	ENOG4105RJI	
Tresu_0025	ENOG4108ENG	carbohydrate kinase, YjeF related protein
Tresu_0027	ENOG41067MG	lrgb family
Tresu_0028	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Tresu_0029	ENOG4105II7	pyrroline-5-carboxylate reductase
Tresu_0031	ENOG4105UQX	Mate efflux family protein
Tresu_0032	ENOG4108ZG0	Ompa motb domain protein
Tresu_0033	ENOG4105KJF	protein tyrosine phosphatase
Tresu_0034	ENOG4105DUM	transcriptional regulator, lysR family
Tresu_0038	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Tresu_0039	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Tresu_0041	ENOG4105C37	(CBS) domain
Tresu_0042	ENOG4108JU6	CBS domain protein
Tresu_0044	ENOG4105D3G	Pseudouridine synthase
Tresu_0045	ENOG4105E0A	ABC, transporter
Tresu_0046	ENOG4105EHG	Permease protein
Tresu_0052	ENOG4105DRS	transport system, permease
Tresu_0053	ENOG4105DSG	hydrolase family 43
Tresu_0054	ENOG4105ETE	Transcriptional regulator (LacI family
Tresu_0055	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Tresu_0056	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Tresu_0059	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
Tresu_0060	ENOG41083HS	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Tresu_0068	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Tresu_0070	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Tresu_0071	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Tresu_0072	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Tresu_0074	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Tresu_0076	ENOG4108IPW	abc transporter atp-binding protein
Tresu_0080	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Tresu_0081	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Tresu_0082	ENOG4108JJB	ABC transporter
Tresu_0083	ENOG4105VKD	bioY protein
Tresu_0086	ENOG4108WAV	Transcriptional regulator
Tresu_0092	ENOG410631K	Membrane
Tresu_0093	ENOG4105BZ8	glutamate synthase
Tresu_0094	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Tresu_0101	ENOG4105D7A	ATP-binding protein
Tresu_0102	ENOG4105UQX	Mate efflux family protein
Tresu_0111	ENOG410600T	transposase
Tresu_0118	ENOG4105C5H	ABC transporter
Tresu_0123	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Tresu_0124	ENOG4105CFF	transcriptional regulator
Tresu_0129	ENOG4105VN1	Heat shock protein
Tresu_0131	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Tresu_0132	ENOG4105CAQ	asparagine synthetase
Tresu_0134	ENOG4107AYK	membrAne
Tresu_0136	ENOG4105C6E	dna polymerase iii
Tresu_0143	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Tresu_0144	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
Tresu_0145	ENOG4105BZU	Histidine kinase
Tresu_0151	ENOG410646M	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Tresu_0159	ENOG4105CEY	Amp-dependent synthetase and ligase
Tresu_0160	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Tresu_0163	ENOG4105CGK	Exodeoxyribonuclease III
Tresu_0166	ENOG4105F1A	Pyruvate formate-lyase
Tresu_0169	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Tresu_0170	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tresu_0171	ENOG4105C22	threonyL-tRNA synthetase
Tresu_0173	ENOG4108YS0	lipoprotein YafL
Tresu_0174	ENOG4105RKW	reductase (By
Tresu_0178	ENOG4105WPN	DNA integration recombination invertion protein
Tresu_0182	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Tresu_0183	ENOG41089XN	
Tresu_0186	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tresu_0187	ENOG4105EYW	Ion transport protein
Tresu_0189	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tresu_0190	ENOG4105D78	K07001 NTE family protein
Tresu_0200	ENOG4107R3N	Filamentation induced by cAMP protein fic
Tresu_0201	ENOG4105DZR	Type I site-specific deoxyribonuclease
Tresu_0204	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Tresu_0207	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Tresu_0216	ENOG4105E4P	ATPase (AAA
Tresu_0221	ENOG4105C2F	Histidine kinase
Tresu_0222	ENOG410874W	AraC family transcriptional regulator
Tresu_0223	ENOG4105DFW	ABC transporter
Tresu_0224	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Tresu_0231	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tresu_0232	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tresu_0234	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Tresu_0238	ENOG4105CFP	Peptidase U32
Tresu_0248	ENOG4108K5P	(LipO)protein
Tresu_0256	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Tresu_0258	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Tresu_0260	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Tresu_0261	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
Tresu_0287	ENOG4108UUM	single-stranded DNA-binding protein
Tresu_0293	ENOG4105EP9	oxidoreductase
Tresu_0296	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Tresu_0298	ENOG4105CJ2	(LipO)protein
Tresu_0299	ENOG4105C8J	)-transporter
Tresu_0318	ENOG4105DSE	periplasmic solute binding protein
Tresu_0319	ENOG4108UZE	carboxy-peptidase
Tresu_0320	ENOG4105DIK	(ABC) transporter
Tresu_0338	ENOG4105BZ8	glutamate synthase
Tresu_0342	ENOG4105CTQ	phosphohexokinase
Tresu_0345	ENOG4105EIB	trna rrna methyltransferase
Tresu_0347	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_0349	ENOG4106KG8	
Tresu_0350	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Tresu_0351	ENOG4105MQ3	flagellar protein FliS
Tresu_0352	ENOG4106VWR	
Tresu_0354	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
Tresu_0355	ENOG4105DF5	DNA topoisomerase IV, subunit A
Tresu_0357	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Tresu_0359	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Tresu_0367	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Tresu_0368	ENOG4105CV8	reductase
Tresu_0372	ENOG4107YZD	Protein of unknown function DUF115
Tresu_0373	ENOG4105CJN	penicillin-binding protein
Tresu_0374	ENOG4105C3F	Signal peptidase i
Tresu_0375	ENOG4105DR5	peptidase
Tresu_0378	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Tresu_0381	ENOG4108ZP8	Acetolactate synthase small subunit
Tresu_0382	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Tresu_0386	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Tresu_0387	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
Tresu_0388	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Tresu_0389	ENOG4108Q9V	regulatoR
Tresu_0390	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Tresu_0391	ENOG4105DZ1	carboxypeptidase
Tresu_0392	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Tresu_0394	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Tresu_0395	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tresu_0397	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Tresu_0398	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tresu_0400	ENOG4108Z29	Flavodoxin
Tresu_0401	ENOG4105VUC	UPF0237 protein
Tresu_0402	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
Tresu_0404	ENOG4105DM4	PTS System
Tresu_0406	ENOG4105CHR	reductase
Tresu_0407	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Tresu_0410	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Tresu_0411	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Tresu_0418	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
Tresu_0419	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tresu_0421	ENOG4108IUM	Glycogen debranching enzyme
Tresu_0428	ENOG410600T	transposase
Tresu_0433	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Tresu_0436	ENOG4105CH7	arginosuccinase
Tresu_0437	ENOG4107R0W	ABC transporter
Tresu_0438	ENOG4105E5Q	amino acid AbC transporter
Tresu_0440	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Tresu_0446	ENOG4105I08	Pseudouridine synthase
Tresu_0447	ENOG4105C2M	dna polymerase I
Tresu_0448	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Tresu_0450	ENOG4108Z66	YbaK ebsC protein
Tresu_0451	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Tresu_0452	ENOG4105D6A	Electron transport complex
Tresu_0454	ENOG4105DZB	Electron transport complex
Tresu_0455	ENOG4105DGN	Electron transport complex
Tresu_0458	ENOG4107S6Z	Na H antiporter
Tresu_0460	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Tresu_0461	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Tresu_0462	ENOG4107Z25	Basic membrane protein
Tresu_0463	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Tresu_0465	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Tresu_0466	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tresu_0467	ENOG4105CB5	ATP-dependent DNA helicase recG
Tresu_0469	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tresu_0471	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_0472	ENOG4108KQ5	Integrase catalytic subunit
Tresu_0477	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Tresu_0478	ENOG4105CPF	Cell wall formation (By similarity)
Tresu_0479	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Tresu_0482	ENOG4105C8V	SAICAR synthetase
Tresu_0483	ENOG4107V9H	nitrite transporter
Tresu_0484	ENOG4107S1W	4-alpha-glucanotransferase
Tresu_0486	ENOG4105D98	threonine synthase
Tresu_0488	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Tresu_0489	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Tresu_0491	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Tresu_0494	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Tresu_0497	ENOG41090QR	
Tresu_0498	ENOG4108IMY	Transcriptional regulator
Tresu_0504	ENOG4109015	Biopolymer transport protein exbD tolR
Tresu_0523	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tresu_0524	ENOG4105D9Q	decarboxylase (Beta subunit)
Tresu_0525	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_0536	ENOG4107QM5	aconitate hydratase
Tresu_0546	ENOG4105E4P	ATPase (AAA
Tresu_0549	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
Tresu_0550	ENOG4105KPE	licD family
Tresu_0554	ENOG4105E4P	ATPase (AAA
Tresu_0575	ENOG4105E4P	ATPase (AAA
Tresu_0578	ENOG4105WMR	Protein CrcB homolog
Tresu_0579	ENOG4105CJW	magnesium transporter
Tresu_0589	ENOG4107QTH	restriction modification system DNA specificity domain
Tresu_0595	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Tresu_0598	ENOG41067SE	Tetr family transcriptional regulator
Tresu_0602	ENOG4105C8T	Leucyl-tRNA synthetase
Tresu_0607	ENOG4107UKG	Glycosyl transferase, family 4
Tresu_0608	ENOG4105C75	arginyL-tRNA synthetase
Tresu_0610	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tresu_0611	ENOG4105CFG	Acts as a chaperone (By similarity)
Tresu_0612	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tresu_0616	ENOG4108UZE	carboxy-peptidase
Tresu_0621	ENOG4105EG2	ABC transporter, permease
Tresu_0622	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Tresu_0623	ENOG4105C5X	domain protein
Tresu_0624	ENOG41062BZ	domain protein
Tresu_0626	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Tresu_0627	ENOG4105DXN	mazG family
Tresu_0628	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Tresu_0629	ENOG41075H3	AraC family transcriptional regulator
Tresu_0631	ENOG4105CKI	cobalamin synthesis protein
Tresu_0634	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Tresu_0638	ENOG41084YP	30S ribosomal protein S21
Tresu_0639	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Tresu_0640	ENOG4105E09	nadh pyrophosphatase
Tresu_0643	ENOG41067QW	Transcriptional regulator
Tresu_0645	ENOG4107QMH	DNA methylase
Tresu_0671	ENOG4105CEC	DNA methylase N-4 N-6
Tresu_0708	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Tresu_0747	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
Tresu_0776	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Tresu_0785	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
Tresu_0805	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Tresu_0807	ENOG4105DWF	phosphomethylpyrimidine kinase
Tresu_0808	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Tresu_0809	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Tresu_0812	ENOG4105DZ0	fad dependent oxidoreductase
Tresu_0818	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Tresu_0821	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Tresu_0823	ENOG4105DC7	peptidase M24
Tresu_0824	ENOG4105CJR	Integral membrane protein (MviN
Tresu_0828	ENOG4105CKU	formyltetrahydrofolate synthetase
Tresu_0829	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
Tresu_0830	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Tresu_0831	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Tresu_0832	ENOG4105BZU	Histidine kinase
Tresu_0834	ENOG410828M	hemerythrin-like, metal-binding protein
Tresu_0839	ENOG4105BZG	amino acid carrier protein
Tresu_0841	ENOG4105EMN	RNA polymerase sigma factor
Tresu_0847	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Tresu_0850	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Tresu_0865	ENOG4105UIB	(ABC) transporter
Tresu_0866	ENOG4108JQ9	ABC transporter
Tresu_0867	ENOG4107TFB	basic membrane
Tresu_0868	ENOG4108KQ5	Integrase catalytic subunit
Tresu_0880	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Tresu_0881	ENOG4105CUZ	uba thif-type nad fad binding protein
Tresu_0882	ENOG4105ER2	Ompa motb domain protein
Tresu_0883	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_0885	ENOG4107QSA	Oxaloacetate decarboxylase
Tresu_0886	ENOG4105D9Q	decarboxylase (Beta subunit)
Tresu_0891	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Tresu_0892	ENOG41087JC	Protein of unknown function (DUF464)
Tresu_0893	ENOG4105K46	50S ribosomal protein l27
Tresu_0894	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tresu_0895	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Tresu_0898	ENOG4107ZFZ	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Tresu_0899	ENOG4105E9H	Lytic Murein transglycosylase
Tresu_0903	ENOG4105VIE	preprotein translocase, subunit YajC
Tresu_0904	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tresu_0905	ENOG4107XHD	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tresu_0906	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Tresu_0909	ENOG4105DPN	Oligoendopeptidase f
Tresu_0910	ENOG4105I76	(LipO)protein
Tresu_0911	ENOG4105C5H	ABC transporter
Tresu_0912	ENOG4105CMR	udp-glucose 4-epimerase
Tresu_0913	ENOG4107S4Y	M20 DapE family protein YgeY
Tresu_0917	ENOG4105BZU	Histidine kinase
Tresu_0919	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tresu_0920	ENOG410600T	transposase
Tresu_0921	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
Tresu_0926	ENOG4105DZR	Type I site-specific deoxyribonuclease
Tresu_0933	ENOG4108HKT	sucrose-6-phosphate hydrolase
Tresu_0934	ENOG4105D7K	pfkb domain protein
Tresu_0936	ENOG41090A1	ferritin
Tresu_0950	ENOG4105Q84	sucrose synthase
Tresu_0960	ENOG4105CHR	reductase
Tresu_0963	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Tresu_0964	ENOG4105CAS	nag kinase
Tresu_0965	ENOG4105C8Y	Acetylornithine aminotransferase
Tresu_0966	ENOG41090KZ	
Tresu_0968	ENOG4105CDH	Citrulline--aspartate ligase
Tresu_0969	ENOG4105CP7	Triose-phosphate isomerase
Tresu_0970	ENOG4105CAH	Chromate
Tresu_0973	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Tresu_0974	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Tresu_0975	ENOG4108VQJ	O-methyltransferase
Tresu_0976	ENOG4105C0A	alcohol dehydrogenase
Tresu_0978	ENOG4105FDK	ABC transporter
Tresu_0979	ENOG4105FAV	ABC, transporter
Tresu_0980	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tresu_0981	ENOG4105C98	muts2 protein
Tresu_0982	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Tresu_0984	ENOG4107QP8	phosphohexose isomerase
Tresu_0985	ENOG4105F8V	Hydrolase, tatD family
Tresu_0988	ENOG4105VFF	UPF0102 protein
Tresu_0989	ENOG4108IUF	type iii secretion
Tresu_0991	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Tresu_0992	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Tresu_0993	ENOG4107GQ3	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Tresu_0994	ENOG4105VB6	UPF0109 protein
Tresu_0996	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Tresu_0997	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Tresu_1000	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Tresu_1002	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Tresu_1012	ENOG4105CKK	Glycosyl transferase, family 2
Tresu_1032	ENOG4105CPN	adenine deaminase
Tresu_1033	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Tresu_1042	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Tresu_1043	ENOG4105E1F	short-chain dehydrogenase reductase
Tresu_1044	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Tresu_1045	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Tresu_1046	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tresu_1047	ENOG41082MQ	UPF0178 protein
Tresu_1048	ENOG4106BMT	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
Tresu_1050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Tresu_1051	ENOG41084MZ	50S ribosomal protein L35
Tresu_1052	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Tresu_1054	ENOG4105D2N	Aldolase
Tresu_1058	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Tresu_1059	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Tresu_1060	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Tresu_1064	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tresu_1066	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Tresu_1068	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Tresu_1069	ENOG41080VC	Galactokinase (EC 2.7.1.6)
Tresu_1070	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Tresu_1071	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
Tresu_1073	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Tresu_1075	ENOG41090Q2	
Tresu_1077	ENOG4107W7Y	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Tresu_1078	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Tresu_1079	ENOG4105DR5	peptidase
Tresu_1080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Tresu_1081	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
Tresu_1086	ENOG410600T	transposase
Tresu_1101	ENOG4107QSV	RmuC domain protein
Tresu_1113	ENOG4107QTH	restriction modification system DNA specificity domain
Tresu_1114	ENOG4105CVR	type I restriction-modification system
Tresu_1115	ENOG4108F3G	Type I restriction-modification system, R subunit
Tresu_1120	ENOG4108ZC9	flagellar basal-body rod protein flgc
Tresu_1121	ENOG41069WH	flagellar hook-basal body complex
Tresu_1122	ENOG4107U2N	Flagellar M-ring protein
Tresu_1123	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tresu_1124	ENOG4105W2B	Flagellar assembly protein
Tresu_1125	ENOG4108JIR	Flagellum-specific ATP synthase
Tresu_1128	ENOG4105FA0	parb-like partition protein
Tresu_1129	ENOG4108JQC	penicillin-binding protein 1A
Tresu_1130	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Tresu_1131	ENOG4108R6K	riboflavin synthase, subunit alpha
Tresu_1132	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Tresu_1134	ENOG4105CUT	histidyl-tRNA synthetase
Tresu_1135	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Tresu_1137	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Tresu_1142	ENOG4105X4X	Protein of unknown function DUF115
Tresu_1143	ENOG410698I	
Tresu_1147	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Tresu_1149	ENOG4105CSA	Coproporphyrinogen iii oxidase
Tresu_1150	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tresu_1151	ENOG4105EEI	dihydropteroate synthase
Tresu_1154	ENOG41083V3	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Tresu_1155	ENOG4108CER	Uncharacterized protein conserved in bacteria (DUF2225)
Tresu_1156	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Tresu_1160	ENOG4105M6F	mutator MutT protein
Tresu_1164	ENOG4105WN5	stage II sporulation protein
Tresu_1171	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Tresu_1172	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tresu_1173	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tresu_1174	ENOG4108ZVA	radical SAM domain protein
Tresu_1176	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Tresu_1177	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Tresu_1178	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Tresu_1180	ENOG4107NGC	Flagellar filament outer layer protein
Tresu_1183	ENOG4105C5I	Dehydrogenase
Tresu_1189	ENOG4105VCQ	rubredoxin
Tresu_1195	ENOG4107QMH	DNA methylase
Tresu_1199	ENOG4105C1J	atp-dependent rna helicase
Tresu_1200	ENOG4105C5H	ABC transporter
Tresu_1202	ENOG4105DZP	Membrane-associated zinc metalloprotease
Tresu_1203	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Tresu_1204	ENOG4105KNE	Phosphatidate cytidylyltransferase
Tresu_1205	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Tresu_1206	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Tresu_1207	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Tresu_1208	ENOG4105CE9	30S ribosomal protein S2
Tresu_1209	ENOG4108Z03	MAF-like protein
Tresu_1210	ENOG4105SXG	
Tresu_1211	ENOG4105ZF0	Lipoprotein
Tresu_1212	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Tresu_1213	ENOG41085YX	50S ribosomal protein L32
Tresu_1214	ENOG41084E5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Tresu_1215	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Tresu_1216	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Tresu_1221	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Tresu_1224	ENOG4107SCN	K03215 23S rRNA (uracil1939-C5)-methyltransferase EC 2.1.1.190
Tresu_1225	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Tresu_1226	ENOG41082DI	50s ribosomal protein l31
Tresu_1228	ENOG4105DR4	Methyltransferase
Tresu_1234	ENOG4105K70	DNA-binding protein
Tresu_1235	ENOG41084AY	Binds together with S18 to 16S ribosomal RNA (By similarity)
Tresu_1236	ENOG4105Z8H	single-stranded DNA-binding protein
Tresu_1237	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Tresu_1238	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Tresu_1239	ENOG4105CDU	Replicative dna helicase
Tresu_1242	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Tresu_1243	ENOG4107QVY	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tresu_1246	ENOG4105DFF	Rod shape-determining protein mreb
Tresu_1249	ENOG4105CJN	penicillin-binding protein
Tresu_1250	ENOG4105CNI	cell division protein FtsW
Tresu_1252	ENOG4108JA2	transcriptioN-repair coupling factor
Tresu_1255	ENOG4105PAD	Hydrolase
Tresu_1256	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Tresu_1257	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Tresu_1260	ENOG4105CJ1	ABC, transporter
Tresu_1261	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Tresu_1263	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Tresu_1269	ENOG4108IG5	Transcriptional regulator
Tresu_1270	ENOG4105C34	Pseudouridine synthase
Tresu_1273	ENOG4105DFA	alanine racemase domain protein
Tresu_1274	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Tresu_1279	ENOG4105D98	threonine synthase
Tresu_1280	ENOG4108Z4J	Cytidine monophosphate kinase
Tresu_1282	ENOG4105DFU	Cell wall formation (By similarity)
Tresu_1283	ENOG4105C93	Xylose Isomerase
Tresu_1284	ENOG4105CMG	Carbohydrate kinase
Tresu_1285	ENOG410874W	AraC family transcriptional regulator
Tresu_1286	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tresu_1287	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tresu_1288	ENOG4105BZU	Histidine kinase
Tresu_1291	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Tresu_1292	ENOG41082BE	ankyrin repeat-containing protein
Tresu_1294	ENOG4108JJB	ABC transporter
Tresu_1295	ENOG4108JJB	ABC transporter
Tresu_1297	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Tresu_1298	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Tresu_1299	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Tresu_1300	ENOG4108TJN	glycosyl transferase group 1
Tresu_1302	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Tresu_1304	ENOG4106GEY	
Tresu_1306	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Tresu_1307	ENOG4105DSF	transport protein
Tresu_1310	ENOG4105HFZ	Membrane
Tresu_1311	ENOG4105DVT	helicase
Tresu_1312	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Tresu_1313	ENOG4105C9Q	fumarate hydratase class II
Tresu_1320	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Tresu_1322	ENOG4108IYU	L-aspartate oxidase
Tresu_1324	ENOG4108RYC	glycosyltransferase
Tresu_1331	ENOG4107SJB	teichoic acid biosynthesis
Tresu_1333	ENOG4105KPE	licD family
Tresu_1334	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
Tresu_1337	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Tresu_1338	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
Tresu_1345	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Tresu_1350	ENOG4105DJ0	Poly(A) Polymerase
Tresu_1351	ENOG4105E5G	Alpha beta hydrolase fold
Tresu_1352	ENOG4105C31	Tryptophanyl-tRNA synthetase
Tresu_1353	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Tresu_1354	ENOG4105CHM	Aminotransferase
Tresu_1357	ENOG4107R2W	ABC transporter, permease
Tresu_1358	ENOG4105C2J	ABC transporter
Tresu_1359	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
Tresu_1361	ENOG4105E2V	Glycosyltransferase 36
Tresu_1363	ENOG4106H78	methyltransferase
Tresu_1364	ENOG4105ZFX	
Tresu_1366	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Tresu_1368	ENOG4105C5I	Dehydrogenase
Tresu_1369	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tresu_1370	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tresu_1376	ENOG4105C7N	Xanthine uracil vitamin C permease
Tresu_1378	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tresu_1379	ENOG4105C19	ABC transporter
Tresu_1381	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Tresu_1388	ENOG41063QE	flagellar protein FlaG
Tresu_1393	ENOG4105K8N	protein family UPF0079, ATPase
Tresu_1394	ENOG41072GX	Peptidase M22 Glycoprotease
Tresu_1395	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Tresu_1396	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Tresu_1397	ENOG4105DTJ	flagellar hook-associated protein
Tresu_1401	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tresu_1402	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tresu_1403	ENOG4105BZU	Histidine kinase
Tresu_1404	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Tresu_1405	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Tresu_1407	ENOG41083IJ	DNA-binding protein
Tresu_1408	ENOG41086BH	Binds directly to 16S ribosomal RNA (By similarity)
Tresu_1421	ENOG4105DBV	ornithine carbamoyltransferase
Tresu_1423	ENOG4105SFS	phosphoesterase RecJ domain protein
Tresu_1425	ENOG410600T	transposase
Tresu_1426	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Tresu_1427	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Tresu_1428	ENOG4108TJN	glycosyl transferase group 1
Tresu_1429	ENOG4105D3Q	Sugar transferase
Tresu_1431	ENOG4106B9X	
Tresu_1432	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Tresu_1434	ENOG4107U1W	v-type ATP synthase subunit I
Tresu_1435	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Tresu_1436	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Tresu_1438	ENOG4108RY1	ATP synthase, subunit E
Tresu_1439	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Tresu_1445	ENOG4107R34	abc transporter permease protein
Tresu_1446	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Tresu_1447	ENOG4105HCZ	
Tresu_1450	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Tresu_1465	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Tresu_1466	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tresu_1469	ENOG4105C7K	acetolactate synthase
Tresu_1470	ENOG4106ARS	
Tresu_1472	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Tresu_1474	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tresu_1482	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tresu_1486	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tresu_1487	ENOG4105C0H	protease
Tresu_1488	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Tresu_1490	ENOG4105CU9	asparagine synthetase A
Tresu_1491	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
Tresu_1494	ENOG4105CQ7	ATP-dependent helicase
Tresu_1503	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Tresu_1504	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Tresu_1510	ENOG4105C3K	feS assembly ATPase SufC
Tresu_1517	ENOG4105E5Q	amino acid AbC transporter
Tresu_1518	ENOG4108HW3	(ABC) transporter
Tresu_1519	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tresu_1521	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Tresu_1522	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Tresu_1525	ENOG4105D1H	recombination factor protein RarA
Tresu_1526	ENOG41060K3	Methyltransferase
Tresu_1527	ENOG4105N5T	Radical SAM Protein
Tresu_1532	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tresu_1535	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Tresu_1536	ENOG4105D7B	Flagellar biosynthesis protein flha
Tresu_1537	ENOG4105D00	flagellar biosynthetic protein flhB
Tresu_1538	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Tresu_1539	ENOG4105VS8	Flagellar biosynthetic protein fliq
Tresu_1540	ENOG4105CN7	Flagellar biosynthetic protein FliP
Tresu_1542	ENOG4105DD5	Flagellar motor switch protein
Tresu_1543	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tresu_1544	ENOG41064SM	flagellar basal body-associated protein flil
Tresu_1545	ENOG4107XSU	flagellar motor protein motb
Tresu_1546	ENOG4107R0U	MotA TolQ exbB proton channel
Tresu_1547	ENOG41068WV	flagellar FlbD family protein
Tresu_1549	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tresu_1550	ENOG4105BZU	Histidine kinase
Tresu_1551	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Tresu_1553	ENOG4105BZE	flagellar hook protein, FlgE
Tresu_1554	ENOG410822I	Flagellar hook capping protein
Tresu_1561	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Tresu_1562	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Tresu_1563	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Tresu_1565	ENOG4105C3F	Signal peptidase i
Tresu_1565	ENOG4105C3F	Signal peptidase i
Tresu_1567	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Tresu_1568	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Tresu_1569	ENOG4107QI1	Mate efflux family protein
Tresu_1575	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_1577	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Tresu_1580	ENOG4105BZF	Glycosyl transferase (Group 1
Tresu_1581	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Tresu_1582	ENOG4105C25	Primosomal protein n'
Tresu_1584	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Tresu_1585	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Tresu_1586	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Tresu_1587	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tresu_1588	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Tresu_1591	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tresu_1592	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Tresu_1593	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Tresu_1595	ENOG4105CNI	cell division protein FtsW
Tresu_1596	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Tresu_1598	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Tresu_1599	ENOG4107YM1	mraZ protein
Tresu_1601	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Tresu_1602	ENOG4105CDY	transcriptional regulatory protein
Tresu_1607	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tresu_1611	ENOG4107Z9R	response regulator
Tresu_1613	ENOG4105YFD	chemotaxis, protein
Tresu_1614	ENOG4105CBS	Chea signal transduction histidine kinase
Tresu_1616	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Tresu_1618	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Tresu_1619	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Tresu_1620	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Tresu_1624	ENOG4107WUB	V-type ATPase 116 kDa subunit
Tresu_1627	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Tresu_1628	ENOG4106447	Preprotein translocase subunit SecG
Tresu_1636	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tresu_1650	ENOG4108R3E	Dna-3-methyladenine glycosylase i
Tresu_1657	ENOG4105F8V	Hydrolase, tatD family
Tresu_1659	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Tresu_1660	ENOG4105DR4	Methyltransferase
Tresu_1661	ENOG4105BZA	Phosphoglycerate kinase
Tresu_1663	ENOG4105C37	(CBS) domain
Tresu_1664	ENOG41082QW	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Tresu_1666	ENOG4105C9A	Phoh family
Tresu_1668	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Tresu_1675	ENOG4105E4P	ATPase (AAA
Tresu_1676	ENOG4108UIC	UPF0340 protein
Tresu_1677	ENOG4105C37	(CBS) domain
Tresu_1682	ENOG4105DVF	Cytosine-specific methyltransferase
Tresu_1685	ENOG4107UWY	Methyltransferase
Tresu_1688	ENOG4105EB3	Histidine kinase
Tresu_1689	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tresu_1701	ENOG4105C8M	UPF0272 protein
Tresu_1702	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Tresu_1706	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_1725	ENOG41082Y9	Single-strand binding protein
Tresu_1773	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tresu_1775	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Tresu_1792	ENOG4105CNT	hydrolase family 2
Tresu_1793	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Tresu_1794	ENOG4105VFU	Rna-binding protein
Tresu_1797	ENOG4105C34	Pseudouridine synthase
Tresu_1798	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Tresu_1799	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tresu_1800	ENOG4108VYJ	response regulator receiver protein
Tresu_1801	ENOG4108DWA	Nad synthetase
Tresu_1802	ENOG4105D6S	protein involved in catabolism of external DNA
Tresu_1804	ENOG4105W0I	repeat-containing protein
Tresu_1805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tresu_1806	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tresu_1807	ENOG4105FE9	pseudouridine synthase
Tresu_1808	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Tresu_1809	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Tresu_1810	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Tresu_1811	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Tresu_1814	ENOG4105DR5	peptidase
Tresu_1820	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Tresu_1821	ENOG4105C0H	protease
Tresu_1823	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Tresu_1824	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Tresu_1826	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Tresu_1831	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Tresu_1832	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Tresu_1833	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tresu_1834	ENOG4105YFD	chemotaxis, protein
Tresu_1835	ENOG4105MJ2	Competence protein
Tresu_1836	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Tresu_1838	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Tresu_1840	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Tresu_1843	ENOG4105SYT	Methylenetetrahydrofolate reductase
Tresu_1846	ENOG4105DG6	mannose-6-phosphate isomerase
Tresu_1848	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Tresu_1849	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Tresu_1851	ENOG4108K0D	peptidase, M48
Tresu_1852	ENOG4108T5G	Adenylate
Tresu_1854	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Tresu_1860	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_1862	ENOG4105D49	3-dehydroquinate synthase
Tresu_1863	ENOG4105C3J	Cysteine desulfurase
Tresu_1865	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tresu_1867	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Tresu_1871	ENOG4105DJV	ribulose-phosphate 3-epimerase
Tresu_1875	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Tresu_1876	ENOG41082YX	Transcriptional regulator, arsr family
Tresu_1880	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tresu_1883	ENOG4105C1J	atp-dependent rna helicase
Tresu_1886	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tresu_1901	ENOG4105F4P	)-transporter
Tresu_1905	ENOG4105ERG	peptidase m48, ste24p
Tresu_1926	ENOG4106PHI	plasmid recombination enzyme
Tresu_1936	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Tresu_1941	ENOG4105ENX	hydrolase
Tresu_1942	ENOG4108W5M	transcriptional regulator
Tresu_1946	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tresu_1948	ENOG4105EPI	acetyltransferase, (GNAT) family
Tresu_1951	ENOG4107QX9	Thiol disulfide interChange protein
Tresu_1954	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Tresu_1956	ENOG4105BZU	Histidine kinase
Tresu_1962	ENOG4105VXN	addiction module toxin, RelE StbE family
Tresu_1987	ENOG4107V6I	Cytosine-specific methyltransferase
Tresu_1988	ENOG4105PZN	Type II restriction enzyme NlaIV
Tresu_1989	ENOG4107RSM	transcriptional regulator
Tresu_1991	ENOG410600T	transposase
Tresu_1995	ENOG410600T	transposase
Tresu_1999	ENOG4108XG2	Histidine kinase
Tresu_2002	ENOG4105E4P	ATPase (AAA
Tresu_2003	ENOG4105QNF	Outer membrane lipoprotein
Tresu_2007	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Tresu_2010	ENOG4105CNT	hydrolase family 2
Tresu_2015	ENOG4108JJB	ABC transporter
Tresu_2019	ENOG4107S17	Phosphate-binding protein
Tresu_2020	ENOG4105C8U	phosphate abc transporter
Tresu_2021	ENOG4105E2Z	phosphate ABC transporter (Permease
Tresu_2022	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Tresu_2023	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Tresu_2026	ENOG4108M8H	domain protein
Tresu_2027	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tresu_2028	ENOG4105BZU	Histidine kinase
Tresu_2029	ENOG4105W5Q	DNA repair protein (RadC
Tresu_2030	ENOG4105C0H	protease
Tresu_2031	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Tresu_2034	ENOG41084P6	50S ribosomal protein l28
Tresu_2036	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Tresu_2038	ENOG4105C5S	asparaginyl-tRNA synthetase
Tresu_2042	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Tresu_2043	ENOG4105BZU	Histidine kinase
Tresu_2048	ENOG4105DRP	amino acid AbC transporter
Tresu_2049	ENOG4105GBT	ABC transporter
Tresu_2050	ENOG4105CDA	abc transporter atp-binding protein
Tresu_2053	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
Tresu_2055	ENOG4105C7K	acetolactate synthase
Tresu_2057	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tresu_2059	ENOG4105FA0	parb-like partition protein
Tresu_2060	ENOG4107QJE	Chromosome Partitioning Protein
Tresu_2064	ENOG4108JDX	DNA polymerase iii, epsilon subunit
Tresu_2065	ENOG4105C3S	Mate efflux family protein
Tresu_2066	ENOG41068JE	domain protein
Tresu_2067	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Tresu_2070	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tresu_2076	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Tresu_2077	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Tresu_2079	ENOG4105C0P	Mg chelatase subunit ChlI
Tresu_2080	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tresu_2082	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Tresu_2085	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Tresu_2087	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Tresu_2088	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Tresu_2089	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Tresu_2090	ENOG41080JB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Tresu_2091	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Tresu_2092	ENOG4105CHV	Transcription elongation factor NusA
Tresu_2093	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Tresu_2094	ENOG410600T	transposase
Tresu_2097	ENOG4105D07	Signal peptide peptidase, SppA
Tresu_2099	ENOG4108UJD	30S ribosomal protein S9
Tresu_2100	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Tresu_2102	ENOG4108RAC	Rubrerythrin
Tresu_2104	ENOG4108UMN	azlc family
Tresu_2105	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tresu_2106	ENOG4105F38	ABC transporter, permease
Tresu_2107	ENOG4105D38	putrescine abc transporter
Tresu_2109	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Tresu_2111	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Tresu_2116	ENOG4105JKW	Valine--pyruvate aminotransferase
Tresu_2118	ENOG41066A3	ATP guanido phosphotransferase
Tresu_2119	ENOG4108Z0C	Uvrb UvrC protein
Tresu_2121	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Tresu_2124	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Tresu_2129	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Tresu_2133	ENOG4105CHH	sulfate transporter
Tresu_2134	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tresu_2135	ENOG4105C3G	gtp-binding protein
Tresu_2136	ENOG4105D3G	Pseudouridine synthase
Tresu_2139	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
Tresu_2140	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Tresu_2141	ENOG4105CFP	Peptidase U32
Tresu_2143	ENOG4105CVG	Homoserine O-transsuccinylase
Tresu_2150	ENOG4105C8Q	Methyl-accepting chemotaxis
Tresu_2151	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tresu_2152	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Tresu_2153	ENOG4105UQX	Mate efflux family protein
Tresu_2155	ENOG4105CMG	Carbohydrate kinase
Tresu_2156	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Tresu_2160	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Tresu_2163	ENOG4108IJ2	phosphate acetyltransferase
Tresu_2166	ENOG4105DK7	lysyl-tRNA synthetase
Tresu_2172	ENOG4105C5H	ABC transporter
Tresu_2176	ENOG410600T	transposase
Tresu_2178	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tresu_2179	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Tresu_2180	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Tresu_2189	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Tresu_2195	ENOG4105EG2	ABC transporter, permease
Tresu_2197	ENOG4107FKK	extracellular solute-binding protein family 1
Tresu_2198	ENOG4105FKQ	transcriptional regulator
Tresu_2199	ENOG4108UHU	Aldolase
Tresu_2202	ENOG4105D22	carbon starvation protein
Tresu_2204	ENOG4105CTQ	phosphohexokinase
Tresu_2205	ENOG4108V0P	LemA family
Tresu_2207	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tresu_2208	ENOG4105BZU	Histidine kinase
Tresu_2209	ENOG4105E4C	Lytic transglycosylase catalytic
Tresu_2210	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Tresu_2211	ENOG4108IQE	Amp-dependent synthetase and ligase
Tresu_2214	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Tresu_2215	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tresu_2216	ENOG4105BZU	Histidine kinase
Tresu_2219	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Tresu_2222	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Tresu_2223	ENOG4107XGZ	Hydrolase
Tresu_2224	ENOG4105DFM	M18 family aminopeptidase
Tresu_2226	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Tresu_2263	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Tresu_2264	ENOG4108JQ1	Dehydrogenase
Tresu_2265	ENOG4105VPX	protein, conserved in bacteria
Tresu_2267	ENOG4105C59	p-type ATPase
Tresu_2269	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tresu_2270	ENOG4107RWR	Sodium hydrogen exchanger
Tresu_2273	ENOG4105KZ7	phosphocarrier protein hpr
Tresu_2274	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tresu_2277	ENOG4105G3C	Type iv pilus assembly
Tresu_2281	ENOG4105IJJ	transcriptional regulator, crp fnr family
Tresu_2282	ENOG4107QWW	Cell wall formation (By similarity)
Tresu_2283	ENOG4105C8N	cysteinyl-tRNA synthetase
Tresu_2287	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Tresu_2289	ENOG4105C12	Phosphoribosylglycinamide synthetase
Tresu_2290	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Tresu_2291	ENOG4105C1A	potassium transporter peripheral membrane
Tresu_2292	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Tresu_2293	ENOG4105D8K	carboxyl transferase
Tresu_2295	ENOG4105EPW	hflc protein
Tresu_2296	ENOG4107RIZ	hflk protein
Tresu_2299	ENOG4105YES	addiction module antidote protein
Tresu_2303	ENOG4105MA4	psp1 domain protein
Tresu_2306	ENOG4105DR5	peptidase
Tresu_2307	ENOG4105F8V	Hydrolase, tatD family
Tresu_2308	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Tresu_2314	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Tresu_2315	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tresu_2316	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Tresu_2321	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Tresu_2324	ENOG41085W3	Transposase
Tresu_2325	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
Tresu_2328	ENOG4105E4P	ATPase (AAA
Tresu_2330	ENOG4105CY0	Metallo-Beta-Lactamase
Tresu_2332	ENOG4108UT2	hemolysin iii
Tresu_2333	ENOG4105CNN	ABC, transporter
Tresu_2335	ENOG4105DFW	ABC transporter
Tresu_2336	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tresu_2341	ENOG4108JJB	ABC transporter
Tresu_2347	ENOG4105F8J	Adenylate Guanylate cyclase
Tresu_2352	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Tresu_2353	ENOG4105C2J	ABC transporter
Tresu_2354	ENOG4107R9N	ABC transporter
Tresu_2355	ENOG41062B0	ABC transporter, permease
Tresu_2356	ENOG41075H3	AraC family transcriptional regulator
Tresu_2357	ENOG4105I03	Flagellin
Tresu_2360	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Tresu_2361	ENOG4105D64	Mechanosensitive ion channel
Tresu_2365	ENOG4105G9E	
Tresu_2368	ENOG4105VEM	Conserved domain protein
Tresu_2370	ENOG4108I7Y	domain protein
Tresu_2371	ENOG4108YZ4	nudix hydrolase
Tresu_2373	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Tresu_2375	ENOG4105CSM	endonuclease III
Tresu_2376	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Tresu_2378	ENOG4105CPC	Aldo Keto reductase
Tresu_2381	ENOG4105DKW	ABC transporter
Tresu_2382	ENOG4105EMY	transcriptional regulator
Tresu_2384	ENOG410600T	transposase
Tresu_2390	ENOG4108IUZ	ABC transporter
Tresu_2392	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Tresu_2397	ENOG4105K5B	UPF0225 protein
Tresu_2398	ENOG4105DZS	Phenylacetate-CoA ligase
Tresu_2404	ENOG4107W2M	Sodium hydrogen exchanger
Tresu_2407	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tresu_2408	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Tresu_2412	ENOG4107MD5	glycoside hydrolase, family
Tresu_2414	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Tresu_2415	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Tresu_2416	ENOG4105SCY	DNAK suppressor
Tresu_2418	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tresu_2423	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tresu_2424	ENOG4108IV0	ABC, transporter
Tresu_2425	ENOG4105C0Z	ABC transporter
Tresu_2426	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tresu_2427	ENOG4105C32	Amino acid ABC transporter (Permease)
Tresu_2430	ENOG4108ZT0	50S ribosomal protein l17
Tresu_2431	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tresu_2432	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Tresu_2433	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tresu_2434	ENOG41067V7	50S ribosomal protein L36
Tresu_2435	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Tresu_2436	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Tresu_2437	ENOG4105VPB	50S ribosomal protein L30
Tresu_2438	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Tresu_2439	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Tresu_2440	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Tresu_2441	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Tresu_2442	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Tresu_2443	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tresu_2444	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Tresu_2445	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Tresu_2446	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Tresu_2447	ENOG41086S0	50s ribosomal protein l29
Tresu_2448	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Tresu_2449	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Tresu_2450	ENOG41082G4	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Tresu_2451	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Tresu_2452	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tresu_2453	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Tresu_2454	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Tresu_2455	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Tresu_2456	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Tresu_2457	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tresu_2458	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Tresu_2459	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Tresu_2460	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tresu_2461	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tresu_2462	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Tresu_2463	ENOG4108VZM	50s ribosomal protein L10
Tresu_2464	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Tresu_2465	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Tresu_2466	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Tresu_2467	ENOG410683Z	Preprotein translocase SecE subunit
Tresu_2468	ENOG41084ED	50S ribosomal protein L33
Tresu_2469	ENOG4105D7W	serine acetyltransferase
Tresu_2480	ENOG4107WGG	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Tresu_2481	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Tresu_2482	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Tresu_2483	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Tresu_2485	ENOG4105BZU	Histidine kinase
Tresu_2490	ENOG4105C9M	aspartyl-trna synthetase
Tresu_2491	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Tresu_2493	ENOG4108IUJ	4-alpha-glucanotransferase
Tresu_2494	ENOG4105ETE	Transcriptional regulator (LacI family
Tresu_2498	ENOG4105CK7	Sodium proline symporter
Tresu_2500	ENOG4105C7J	ABC transporter, permease
Tresu_2501	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Tresu_2503	ENOG4108TSD	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Tresu_2505	ENOG4108UMI	ABC transporter, permease
Tresu_2507	ENOG4105C34	Pseudouridine synthase
Tresu_2509	ENOG4107EFR	Flavocytochrome c
Tresu_2513	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Tresu_2515	ENOG410835P	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Tresu_2516	ENOG4108RE9	Phosphodiesterase
Tresu_2522	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Tresu_2523	ENOG4105CNU	cell division protein FtsK
Tresu_2526	ENOG4105D01	(LipO)protein
Tresu_2528	ENOG4105CHM	Aminotransferase
Tresu_2529	ENOG4108ZB6	transcriptional regulator AsnC family
Tresu_2530	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Tresu_2531	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Tresu_2532	ENOG4105E66	phosphoriboisomerase A
Tresu_2533	ENOG4105E2X	shikimate dehydrogenase
Tresu_2534	ENOG4105T73	
Tresu_2535	ENOG4105CFI	type iii restriction protein res subunit
Tresu_2536	ENOG4105KY8	Rubrerythrin
Tresu_2540	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Tresu_2541	ENOG410600T	transposase
Tresu_2547	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
Tresu_2549	ENOG4105CTM	Glycoside hydrolase family 5
Tresu_2556	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tresu_2557	ENOG4108Z4K	mutator MutT protein
Tresu_2558	ENOG4107QZM	n-acetylglutamate synthase
Tresu_2559	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tresu_2560	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tresu_2617	ENOG4105NVB	glycoside hydrolase, family 19
Tresu_2628	ENOG41076CZ	activating enzyme
Tresu_2629	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Tresu_2653	ENOG410600T	transposase