locus-tag	class	description
FY034_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY034_00010	COG0592	DNA-directed DNA polymerase activity
FY034_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY034_00020	COG0187	DNA topoisomerase II activity
FY034_00030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY034_00035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY034_00125	COG0305	Participates in initiation and elongation during chromosome replication
FY034_00140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY034_00150	COG1360	Flagellar Motor Protein
FY034_00165	COG0280	phosphate acetyltransferase
FY034_00165	COG0857	belongs to the CobB CobQ family
FY034_00180	COG2022	thiamine diphosphate biosynthetic process
FY034_00185	COG0352	thiamine-phosphate diphosphorylase activity
FY034_00190	COG1242	4 iron, 4 sulfur cluster binding
FY034_00230	COG5002	protein histidine kinase activity
FY034_00230	COG0784	Response regulator, receiver
FY034_00230	COG2205	protein histidine kinase activity
FY034_00235	COG3437	response regulator, receiver
FY034_00250	COG1490	D-aminoacyl-tRNA deacylase activity
FY034_00265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY034_00275	COG3481	metal-dependent phosphohydrolase, HD sub domain
FY034_00280	COG0745	RESPONSE REGULATOR receiver
FY034_00285	COG2205	protein histidine kinase activity
FY034_00295	COG0534	Mate efflux family protein
FY034_00320	COG0519	Catalyzes the synthesis of GMP from XMP
FY034_00340	COG0688	phosphatidylethanolamine metabolic process
FY034_00360	COG0138	bifunctional purine biosynthesis protein purh
FY034_00380	COG0730	response to heat
FY034_00385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY034_00420	COG2203	Gaf domain
FY034_00420	COG3706	GGDEF domain
FY034_00420	COG4251	negative regulation of phosphorylation
FY034_00420	COG5001	Diguanylate cyclase
FY034_00455	COG1280	lysine exporter protein (LysE YggA)
FY034_00470	COG0433	COG0433 Predicted ATPase
FY034_00485	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FY034_00500	COG2814	Major facilitator Superfamily
FY034_00505	COG0667	Aldo Keto reductase
FY034_00525	COG3655	Transcriptional regulator
FY034_00530	COG1741	Belongs to the pirin family
FY034_00535	COG1902	pentaerythritol trinitrate reductase activity
FY034_00540	COG0784	Response regulator, receiver
FY034_00540	COG2205	protein histidine kinase activity
FY034_00540	COG2198	Histidine kinase
FY034_00630	COG3550	peptidyl-serine autophosphorylation
FY034_00665	COG0778	Nitroreductase
FY034_00680	COG1309	transcriptional regulator
FY034_00705	COG1346	cytolysis
FY034_00740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY034_00745	COG5002	protein histidine kinase activity
FY034_00750	COG1115	amino acid carrier protein
FY034_00755	COG0789	Transcriptional regulator
FY034_00775	COG2770	Histidine kinase
FY034_00775	COG3437	response regulator, receiver
FY034_00780	COG4191	Histidine kinase
FY034_00790	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY034_00810	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FY034_00815	COG0437	4 iron, 4 sulfur cluster binding
FY034_00820	COG5557	Pfam Polysulphide reductase, NrfD
FY034_00825	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FY034_00830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FY034_00835	COG3290	protein histidine kinase activity
FY034_00835	COG0840	transmembrane signaling receptor activity
FY034_00845	COG3040	lipid binding
FY034_00850	COG0583	DNA-binding transcription factor activity
FY034_00855	COG2814	Major facilitator Superfamily
FY034_00860	COG1690	Belongs to the RtcB family
FY034_00865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY034_00880	COG2852	Protein conserved in bacteria
FY034_00895	COG1309	transcriptional regulator
FY034_00910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY034_00920	COG1970	mechanosensitive ion channel activity
FY034_00925	COG2501	S4 domain
FY034_00950	COG1104	cysteine desulfurase activity
FY034_00965	COG3177	Filamentation induced by cAMP protein fic
FY034_00970	COG0606	chelatase, subunit chli
FY034_00975	COG1496	oxidoreductase activity
FY034_00980	COG0586	Pfam SNARE associated Golgi protein
FY034_00990	COG4974	Belongs to the 'phage' integrase family
FY034_01005	COG0427	acetyl-CoA hydrolase
FY034_01010	COG0101	tRNA pseudouridine synthase activity
FY034_01020	COG0473	3-isopropylmalate dehydrogenase activity
FY034_01025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY034_01060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY034_01065	COG2226	methyltransferase
FY034_01070	COG2070	2-Nitropropane dioxygenase
FY034_01075	COG2873	o-acetylhomoserine
FY034_01105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY034_01110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY034_01115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY034_01120	COG1013	pyruvate-flavodoxin oxidoreductase activity
FY034_01120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FY034_01120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY034_01120	COG0674	pyruvate-flavodoxin oxidoreductase activity
FY034_01125	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FY034_01130	COG0826	peptidase U32
FY034_01140	COG0745	RESPONSE REGULATOR receiver
FY034_01145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY034_01155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY034_01175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY034_01180	COG3320	Male sterility
FY034_01180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_01185	COG1238	metal cluster binding
FY034_01220	COG0297	glycogen (starch) synthase activity
FY034_01245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_01260	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY034_01265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY034_01285	COG3177	Filamentation induced by cAMP protein fic
FY034_01290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY034_01300	COG0163	prenyltransferase activity
FY034_01305	COG0426	domain, Protein
FY034_01310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FY034_01315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FY034_01320	COG4191	Histidine kinase
FY034_01330	COG0215	cysteine-tRNA ligase activity
FY034_01340	COG2204	response regulator
FY034_01345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY034_01370	COG1047	Peptidyl-prolyl cis-trans
FY034_01375	COG1872	DUF167
FY034_01390	COG0483	inositol monophosphate 1-phosphatase activity
FY034_01400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY034_01440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY034_01480	COG0545	Peptidyl-prolyl cis-trans isomerase
FY034_01495	COG2824	Alkylphosphonate utilization operon protein PhnA
FY034_01500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FY034_01535	COG2226	methyltransferase
FY034_01550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY034_01555	COG1126	abc transporter atp-binding protein
FY034_01580	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY034_01585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY034_01595	COG0436	Aminotransferase
FY034_01600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY034_01605	COG1469	GTP cyclohydrolase I activity
FY034_01610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY034_01620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY034_01630	COG0424	maF-like protein
FY034_01640	COG0277	FAD linked oxidase domain protein
FY034_01655	COG1530	ribonuclease E activity
FY034_01675	COG0347	Belongs to the P(II) protein family
FY034_01680	COG0004	ammonium transporteR
FY034_01685	COG0347	Belongs to the P(II) protein family
FY034_01695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY034_01700	COG0450	alkyl hydroperoxide reductase
FY034_01725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY034_01735	COG0564	pseudouridine synthase activity
FY034_01745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY034_01755	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FY034_01760	COG0702	epimerase
FY034_01775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY034_01785	COG1127	ABC transporter
FY034_01800	COG0612	Peptidase, M16
FY034_01830	COG0181	hydroxymethylbilane synthase activity
FY034_01835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FY034_01840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY034_01845	COG3118	belongs to the thioredoxin family
FY034_01850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY034_01855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY034_01860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY034_01880	COG2205	protein histidine kinase activity
FY034_01880	COG3437	response regulator, receiver
FY034_01880	COG3850	Histidine kinase
FY034_01880	COG4999	Histidine kinase
FY034_01910	COG0484	heat shock protein binding
FY034_01920	COG2003	Belongs to the UPF0758 family
FY034_01925	COG1968	undecaprenyl-diphosphatase activity
FY034_01940	COG3830	Belongs to the UPF0237 family
FY034_01945	COG0242	peptide deformylase activity
FY034_02035	COG1136	(ABC) transporter
FY034_02055	COG0861	Integral membrane protein TerC family
FY034_02065	COG1704	LemA family
FY034_02085	COG0288	reversible hydration of carbon dioxide
FY034_02090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY034_02105	COG0840	transmembrane signaling receptor activity
FY034_02115	COG2205	protein histidine kinase activity
FY034_02115	COG3437	response regulator, receiver
FY034_02115	COG3850	Histidine kinase
FY034_02115	COG4999	Histidine kinase
FY034_02125	COG3437	response regulator, receiver
FY034_02125	COG3850	Histidine kinase
FY034_02125	COG2205	protein histidine kinase activity
FY034_02125	COG4999	Histidine kinase
FY034_02130	COG2205	protein histidine kinase activity
FY034_02130	COG4999	Histidine kinase
FY034_02130	COG3437	response regulator, receiver
FY034_02130	COG3850	Histidine kinase
FY034_02135	COG2205	protein histidine kinase activity
FY034_02135	COG2198	Histidine kinase
FY034_02135	COG0784	Response regulator, receiver
FY034_02170	COG2201	protein-glutamate methylesterase activity
FY034_02175	COG0247	lactate metabolic process
FY034_02175	COG2181	nitrate reductase activity
FY034_02180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FY034_02190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY034_02195	COG0527	aspartate kinase activity
FY034_02200	COG4771	TonB-dependent receptor
FY034_02210	COG5002	protein histidine kinase activity
FY034_02210	COG0784	Response regulator, receiver
FY034_02210	COG2205	protein histidine kinase activity
FY034_02215	COG0322	excinuclease ABC activity
FY034_02220	COG0004	ammonium transporteR
FY034_02240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY034_02245	COG1151	hydroxylamine reductase activity
FY034_02250	COG3920	Histidine kinase
FY034_02250	COG2202	Pas domain
FY034_02255	COG2197	response regulator
FY034_02285	COG2203	Gaf domain
FY034_02285	COG3706	GGDEF domain
FY034_02285	COG4251	negative regulation of phosphorylation
FY034_02285	COG5001	Diguanylate cyclase
FY034_02290	COG1392	Phosphate transport regulator
FY034_02295	COG0306	phosphate transporter
FY034_02300	COG0745	RESPONSE REGULATOR receiver
FY034_02305	COG5002	protein histidine kinase activity
FY034_02310	COG2062	phosphohistidine phosphatase, SixA
FY034_02320	COG0248	Ppx GppA phosphatase
FY034_02340	COG1785	Belongs to the alkaline phosphatase family
FY034_02345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY034_02355	COG0784	Response regulator, receiver
FY034_02355	COG2205	protein histidine kinase activity
FY034_02355	COG2198	Histidine kinase
FY034_02365	COG3706	GGDEF domain
FY034_02375	COG0688	phosphatidylethanolamine metabolic process
FY034_02380	COG0438	transferase activity, transferring glycosyl groups
FY034_02415	COG1803	Methylglyoxal synthase
FY034_02420	COG0515	serine threonine protein kinase
FY034_02420	COG2815	serine threonine protein kinase
FY034_02455	COG0573	inorganic phosphate transmembrane transporter activity
FY034_02460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY034_02465	COG0704	Plays a role in the regulation of phosphate uptake
FY034_02480	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FY034_02510	COG0535	radical SAM domain protein
FY034_02510	COG1433	Dinitrogenase iron-molybdenum cofactor
FY034_02515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FY034_02525	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FY034_02565	COG2308	Evidence 4 Homologs of previously reported genes of
FY034_02570	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FY034_02575	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FY034_02595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY034_02605	COG0861	Integral membrane protein TerC family
FY034_02615	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FY034_02620	COG1671	Belongs to the UPF0178 family
FY034_02655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_02665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY034_02675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY034_02680	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY034_02685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY034_02690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY034_02695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY034_02700	COG0772	Belongs to the SEDS family
FY034_02705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY034_02710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY034_02715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY034_02720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY034_02725	COG0768	penicillin binding
FY034_02730	COG3116	cell division
FY034_02735	COG0275	rRNA processing
FY034_02740	COG2001	Belongs to the MraZ family
FY034_02765	COG3209	COG3209 Rhs family protein
FY034_02850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FY034_02860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY034_02880	COG0113	porphobilinogen synthase activity
FY034_02900	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FY034_02910	COG4980	gas vesicle protein
FY034_02930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_02935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_02950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY034_02960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY034_02985	COG2208	phosphoserine phosphatase activity
FY034_02985	COG2770	Histidine kinase
FY034_02990	COG4948	Mandelate Racemase Muconate Lactonizing
FY034_03010	COG0371	Dehydrogenase
FY034_03015	COG1126	abc transporter atp-binding protein
FY034_03020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY034_03030	COG1472	Belongs to the glycosyl hydrolase 3 family
FY034_03040	COG3527	Alpha-acetolactate decarboxylase
FY034_03100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FY034_03130	COG2204	response regulator
FY034_03135	COG0765	amino acid transport
FY034_03140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY034_03155	COG2172	sigma factor antagonist activity
FY034_03160	COG1366	Belongs to the anti-sigma-factor antagonist family
FY034_03165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FY034_03165	COG2199	diguanylate cyclase activity
FY034_03210	COG1530	ribonuclease E activity
FY034_03215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY034_03225	COG1136	(ABC) transporter
FY034_03230	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY034_03240	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY034_03250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY034_03265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY034_03280	COG1519	Transferase
FY034_03285	COG1663	tetraacyldisaccharide 4'-kinase activity
FY034_03290	COG0859	PFAM glycosyl transferase family 9
FY034_03295	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FY034_03300	COG1132	(ABC) transporter
FY034_03315	COG1215	transferase activity, transferring glycosyl groups
FY034_03340	COG0438	transferase activity, transferring glycosyl groups
FY034_03340	COG0297	glycogen (starch) synthase activity
FY034_03355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FY034_03365	COG0859	PFAM glycosyl transferase family 9
FY034_03375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FY034_03395	COG5002	protein histidine kinase activity
FY034_03405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY034_03415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY034_03420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY034_03425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY034_03430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY034_03440	COG0131	Imidazoleglycerol-phosphate dehydratase
FY034_03450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY034_03475	COG2048	Heterodisulfide reductase, subunit B
FY034_03485	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FY034_03525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY034_03530	COG1921	L-seryl-tRNASec selenium transferase activity
FY034_03535	COG2186	Transcriptional regulator
FY034_03560	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FY034_03565	COG0617	tRNA 3'-terminal CCA addition
FY034_03565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY034_03565	COG3620	sequence-specific DNA binding
FY034_03570	COG2814	Major facilitator Superfamily
FY034_03580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_03580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_03600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY034_03605	COG0303	'Molybdopterin
FY034_03640	COG0746	molybdenum cofactor guanylyltransferase activity
FY034_03650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY034_03660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY034_03675	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY034_03705	COG1234	tRNA 3'-trailer cleavage
FY034_03715	COG2226	methyltransferase
FY034_03725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY034_03735	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY034_03740	COG0315	cyclic pyranopterin monophosphate synthase activity
FY034_03745	COG1280	lysine exporter protein (LysE YggA)
FY034_03755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY034_03760	COG0840	transmembrane signaling receptor activity
FY034_03780	COG2223	nitrite transmembrane transporter activity
FY034_03785	COG2271	Major facilitator Superfamily
FY034_03805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_03815	COG1053	succinate dehydrogenase
FY034_03815	COG3976	FMN-binding domain protein
FY034_03830	COG1053	succinate dehydrogenase
FY034_03835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY034_03850	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FY034_03855	COG0191	fructose-bisphosphate aldolase activity
FY034_03875	COG2855	membrane
FY034_03880	COG0583	DNA-binding transcription factor activity
FY034_03885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY034_03890	COG1993	acr, cog1993
FY034_03900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY034_03905	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY034_03910	COG0076	glutamate decarboxylase activity
FY034_03915	COG1454	alcohol dehydrogenase
FY034_03920	COG2205	protein histidine kinase activity
FY034_03920	COG0784	Response regulator, receiver
FY034_03920	COG5002	protein histidine kinase activity
FY034_03925	COG0402	S-adenosylhomocysteine deaminase activity
FY034_03950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FY034_03950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FY034_03955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY034_03965	COG1077	Cell shape determining protein MreB Mrl
FY034_03970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY034_03975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY034_04020	COG1923	regulation of RNA biosynthetic process
FY034_04025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY034_04030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY034_04040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FY034_04045	COG2264	protein methyltransferase activity
FY034_04050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY034_04060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY034_04065	COG0348	domain, Protein
FY034_04080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY034_04085	COG2267	carboxylic ester hydrolase activity
FY034_04090	COG3976	FMN-binding domain protein
FY034_04090	COG1053	succinate dehydrogenase
FY034_04130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY034_04135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY034_04150	COG0358	DNA primase activity
FY034_04160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY034_04165	COG0140	phosphoribosyl-ATP diphosphatase activity
FY034_04170	COG0107	imidazoleglycerol-phosphate synthase activity
FY034_04175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY034_04180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY034_04190	COG0751	glycine-tRNA ligase activity
FY034_04195	COG0752	glycyl-tRNA synthetase alpha subunit
FY034_04200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY034_04205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY034_04210	COG0254	rRNA binding
FY034_04215	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FY034_04220	COG3872	metal-dependent enzyme
FY034_04225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY034_04230	COG2890	protein-(glutamine-N5) methyltransferase activity
FY034_04235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FY034_04240	COG2252	PERMEase
FY034_04260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY034_04265	COG3842	ATPase activity
FY034_04295	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FY034_04300	COG3005	denitrification pathway
FY034_04305	COG1151	hydroxylamine reductase activity
FY034_04315	COG1309	transcriptional regulator
FY034_04330	COG1136	(ABC) transporter
FY034_04340	COG0348	domain, Protein
FY034_04360	COG4191	Histidine kinase
FY034_04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY034_04390	COG0243	molybdopterin cofactor binding
FY034_04395	COG0437	4 iron, 4 sulfur cluster binding
FY034_04400	COG0348	domain, Protein
FY034_04415	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FY034_04420	COG5002	protein histidine kinase activity
FY034_04420	COG2205	protein histidine kinase activity
FY034_04420	COG0784	Response regulator, receiver
FY034_04435	COG1196	nuclear chromosome segregation
FY034_04435	COG0739	heme binding
FY034_04435	COG0741	lytic transglycosylase activity
FY034_04440	COG0210	DNA helicase
FY034_04450	COG0175	sulfate reduction
FY034_04460	COG0730	response to heat
FY034_04465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY034_04470	COG0114	fumarate hydratase activity
FY034_04480	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FY034_04495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FY034_04495	COG0674	pyruvate-flavodoxin oxidoreductase activity
FY034_04500	COG2233	PERMEase
FY034_04505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY034_04510	COG0443	Heat shock 70 kDa protein
FY034_04555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY034_04560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY034_04565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY034_04570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY034_04625	COG3604	Transcriptional regulator
FY034_04630	COG0204	Acyl-transferase
FY034_04640	COG4589	Belongs to the CDS family
FY034_04645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY034_04670	COG0204	Acyl-transferase
FY034_04670	COG0318	PFAM AMP-dependent synthetase and ligase
FY034_04695	COG0564	pseudouridine synthase activity
FY034_04700	COG4206	TonB-dependent receptor
FY034_04710	COG5002	protein histidine kinase activity
FY034_04710	COG0784	Response regulator, receiver
FY034_04710	COG2198	Histidine kinase
FY034_04720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY034_04725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY034_04760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY034_04830	COG0305	Participates in initiation and elongation during chromosome replication
FY034_04885	COG0582	viral genome integration into host DNA
FY034_04905	COG0018	arginyl-trna synthetase
FY034_04920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_04925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY034_04930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY034_04935	COG0860	N-Acetylmuramoyl-L-alanine amidase
FY034_04950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY034_04965	COG0437	4 iron, 4 sulfur cluster binding
FY034_04970	COG0243	molybdopterin cofactor binding
FY034_04975	COG2204	response regulator
FY034_04980	COG3852	Histidine kinase
FY034_04995	COG0798	PFAM Bile acid sodium symporter
FY034_05000	COG5002	protein histidine kinase activity
FY034_05000	COG5001	Diguanylate cyclase
FY034_05005	COG0746	molybdenum cofactor guanylyltransferase activity
FY034_05010	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY034_05015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY034_05045	COG0640	Transcriptional regulator
FY034_05070	COG1271	oxidase subunit
FY034_05075	COG1294	oxidase, subunit
FY034_05090	COG0280	phosphate acetyltransferase
FY034_05095	COG0133	tryptophan synthase activity
FY034_05100	COG0135	phosphoribosylanthranilate isomerase activity
FY034_05105	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FY034_05115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY034_05120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY034_05140	COG2373	Large extracellular alpha-helical protein
FY034_05180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY034_05185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY034_05185	COG2010	Cytochrome c
FY034_05200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY034_05210	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY034_05215	COG0285	dihydrofolate synthase activity
FY034_05220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY034_05225	COG0159	tryptophan synthase activity
FY034_05245	COG0805	protein transport
FY034_05250	COG0557	exoribonuclease II activity
FY034_05285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY034_05285	COG1199	ATP-dependent helicase activity
FY034_05290	COG0582	viral genome integration into host DNA
FY034_05305	COG0217	transcriptional regulatory protein
FY034_05310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY034_05315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY034_05320	COG0632	four-way junction helicase activity
FY034_05360	COG1704	LemA family
FY034_05365	COG4095	Psort location CytoplasmicMembrane, score
FY034_05395	COG1940	carbohydrate kinase activity
FY034_05440	COG3156	type II secretion system protein K
FY034_05460	COG2165	general secretion pathway protein
FY034_05495	COG3706	GGDEF domain
FY034_05530	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY034_05570	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FY034_05575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY034_05595	COG1285	pathogenesis
FY034_05610	COG0613	PHP domain protein
FY034_05615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FY034_05655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY034_05660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY034_05670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY034_05680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY034_05685	COG0081	regulation of translation
FY034_05690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY034_05695	COG0222	ribosome binding
FY034_05700	COG0085	RNA polymerase activity
FY034_05705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY034_05710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY034_05715	COG0049	tRNA binding
FY034_05720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY034_05725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY034_05730	COG0051	transcription antitermination factor activity, RNA binding
FY034_05735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY034_05740	COG0088	Forms part of the polypeptide exit tunnel
FY034_05745	COG0089	rRNA binding
FY034_05750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY034_05755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY034_05760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY034_05765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY034_05770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY034_05775	COG0255	Belongs to the universal ribosomal protein uL29 family
FY034_05780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY034_05785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY034_05790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY034_05795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY034_05800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY034_05805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY034_05810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY034_05815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY034_05820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY034_05825	COG1841	ribosomal large subunit assembly
FY034_05830	COG0200	Binds to the 23S rRNA
FY034_05840	COG0563	adenylate kinase activity
FY034_05850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY034_05855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY034_05860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY034_05865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY034_05870	COG0202	RNA polymerase activity
FY034_05875	COG0203	ribosomal protein L17
FY034_05885	COG5000	phosphorelay sensor kinase activity
FY034_05890	COG2204	response regulator
FY034_05895	COG1024	Enoyl-CoA hydratase
FY034_05910	COG2264	protein methyltransferase activity
FY034_05920	COG4260	virion core protein, lumpy skin disease virus
FY034_05930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY034_05935	COG0318	PFAM AMP-dependent synthetase and ligase
FY034_05950	COG1538	Outer membrane efflux protein
FY034_05955	COG0516	GMP reductase activity
FY034_05970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY034_05980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY034_06005	COG1459	type II secretion system
FY034_06015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_06020	COG3209	COG3209 Rhs family protein
FY034_06080	COG1450	Type ii and iii secretion system protein
FY034_06115	COG1450	Type ii and iii secretion system protein
FY034_06125	COG1136	(ABC) transporter
FY034_06125	COG0577	efflux transmembrane transporter activity
FY034_06145	COG2852	Protein conserved in bacteria
FY034_06165	COG4191	Histidine kinase
FY034_06170	COG2204	response regulator
FY034_06180	COG0545	Peptidyl-prolyl cis-trans isomerase
FY034_06200	COG2132	Multicopper oxidase
FY034_06200	COG2132	Multicopper oxidase
FY034_06210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FY034_06245	COG0438	transferase activity, transferring glycosyl groups
FY034_06260	COG0110	maltose O-acetyltransferase activity
FY034_06275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY034_06315	COG0671	phosphoesterase, PA-phosphatase related
FY034_06320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY034_06325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY034_06350	COG5002	protein histidine kinase activity
FY034_06350	COG2205	protein histidine kinase activity
FY034_06350	COG0784	Response regulator, receiver
FY034_06360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY034_06365	COG3259	Nickel-dependent hydrogenase
FY034_06385	COG0840	transmembrane signaling receptor activity
FY034_06390	COG0745	RESPONSE REGULATOR receiver
FY034_06405	COG2197	response regulator
FY034_06420	COG4585	Histidine kinase
FY034_06425	COG2197	response regulator
FY034_06435	COG5002	protein histidine kinase activity
FY034_06440	COG2204	response regulator
FY034_06450	COG2204	response regulator
FY034_06455	COG2197	response regulator
FY034_06460	COG0784	Response regulator, receiver
FY034_06460	COG5002	protein histidine kinase activity
FY034_06480	COG2391	methyltransferase activity
FY034_06495	COG1331	Highly conserved protein containing a thioredoxin domain
FY034_06510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY034_06515	COG1914	H( )-stimulated, divalent metal cation uptake system
FY034_06525	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FY034_06535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY034_06550	COG0515	serine threonine protein kinase
FY034_06555	COG0631	protein serine/threonine phosphatase activity
FY034_06560	COG1716	ATPase activity
FY034_06565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY034_06570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY034_06575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY034_06590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY034_06595	COG0006	proline dipeptidase activity
FY034_06605	COG0439	Biotin carboxylase
FY034_06610	COG0509	glycine decarboxylation via glycine cleavage system
FY034_06620	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FY034_06630	COG2816	NAD+ diphosphatase activity
FY034_06640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY034_06665	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY034_06680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY034_06715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY034_06730	COG0126	phosphoglycerate kinase activity
FY034_06735	COG0149	triose-phosphate isomerase activity
FY034_06770	COG2801	Transposase and inactivated derivatives
FY034_06780	COG2003	Belongs to the UPF0758 family
FY034_06810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY034_06840	COG1396	sequence-specific DNA binding
FY034_06845	COG3829	transcription factor binding
FY034_06850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FY034_06875	COG0481	GTPase activity
FY034_06880	COG0681	Belongs to the peptidase S26 family
FY034_06890	COG1652	LysM domain
FY034_06900	COG0039	L-malate dehydrogenase activity
FY034_06910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FY034_06910	COG0674	pyruvate-flavodoxin oxidoreductase activity
FY034_06915	COG1013	pyruvate-flavodoxin oxidoreductase activity
FY034_06925	COG4221	oxidoreductase activity
FY034_06930	COG2814	Major facilitator Superfamily
FY034_06945	COG1846	Transcriptional regulator
FY034_06960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_07005	COG1605	Chorismate mutase
FY034_07005	COG0077	Prephenate dehydratase
FY034_07015	COG0196	riboflavin kinase activity
FY034_07030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY034_07035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_07045	COG1459	type II secretion system
FY034_07050	COG3852	Histidine kinase
FY034_07055	COG2204	response regulator
FY034_07065	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY034_07070	COG0662	Cupin 2, conserved barrel domain protein
FY034_07070	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FY034_07075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FY034_07075	COG0662	Cupin 2, conserved barrel domain protein
FY034_07080	COG0156	8-amino-7-oxononanoate synthase activity
FY034_07090	COG2226	methyltransferase
FY034_07100	COG0779	Required for maturation of 30S ribosomal subunits
FY034_07105	COG0195	Participates in both transcription termination and antitermination
FY034_07115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY034_07120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY034_07125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY034_07130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY034_07135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY034_07140	COG1185	polyribonucleotide nucleotidyltransferase activity
FY034_07145	COG1166	arginine decarboxylase activity
FY034_07285	COG0740	serine-type endopeptidase activity
FY034_07425	COG4974	Belongs to the 'phage' integrase family
FY034_07450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FY034_07455	COG0730	response to heat
FY034_07465	COG0504	CTP synthase activity
FY034_07470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY034_07475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FY034_07480	COG2201	protein-glutamate methylesterase activity
FY034_07495	COG0835	chemotaxis
FY034_07500	COG0840	transmembrane signaling receptor activity
FY034_07505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY034_07515	COG0643	Histidine kinase
FY034_07515	COG2198	Histidine kinase
FY034_07520	COG0745	RESPONSE REGULATOR receiver
FY034_07535	COG0745	RESPONSE REGULATOR receiver
FY034_07550	COG2205	protein histidine kinase activity
FY034_07560	COG2131	deaminase
FY034_07565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY034_07580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_07580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_07585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY034_07595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FY034_07620	COG2333	competence protein COMEC
FY034_07620	COG0658	competence protein
FY034_07630	COG0124	histidyl-tRNA synthetase
FY034_07665	COG0436	Aminotransferase
FY034_07670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY034_07675	COG0742	ribosomal rna small subunit methyltransferase
FY034_07690	COG1643	Atp-dependent helicase
FY034_07700	COG0437	4 iron, 4 sulfur cluster binding
FY034_07750	COG1773	rubredoxin
FY034_07750	COG1592	Rubrerythrin
FY034_07755	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY034_07765	COG1592	Rubrerythrin
FY034_07790	COG0577	efflux transmembrane transporter activity
FY034_07790	COG1136	(ABC) transporter
FY034_07795	COG0390	transport system, permease component
FY034_07800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY034_07810	COG1414	Transcriptional regulator
FY034_07820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY034_07825	COG0038	chloride channel
FY034_07835	COG1640	4-alpha-glucanotransferase
FY034_07865	COG1509	lysine 2,3-aminomutase activity
FY034_07910	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FY034_07925	COG1846	Transcriptional regulator
FY034_07945	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FY034_07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY034_07955	COG1320	monovalent cation:proton antiporter activity
FY034_07960	COG2212	antiporter activity
FY034_07965	COG1863	multisubunit Na H antiporter MnhE subunit
FY034_07970	COG0651	ATP synthesis coupled electron transport
FY034_07975	COG1006	Multisubunit Na H antiporter MnhC subunit
FY034_07980	COG2111	Na H antiporter
FY034_07985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY034_07985	COG2111	Na H antiporter
FY034_07995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FY034_08010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FY034_08020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY034_08035	COG0516	GMP reductase activity
FY034_08055	COG2814	Major facilitator Superfamily
FY034_08060	COG2204	response regulator
FY034_08075	COG4191	Histidine kinase
FY034_08085	COG0835	chemotaxis
FY034_08095	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY034_08095	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY034_08100	COG1121	(ABC) transporter
FY034_08105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY034_08125	COG0612	Peptidase, M16
FY034_08130	COG2205	protein histidine kinase activity
FY034_08130	COG0784	Response regulator, receiver
FY034_08145	COG0009	L-threonylcarbamoyladenylate synthase
FY034_08155	COG0720	synthase
FY034_08160	COG0602	queuosine metabolic process
FY034_08175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY034_08180	COG0776	regulation of translation
FY034_08185	COG0248	Ppx GppA phosphatase
FY034_08185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY034_08220	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FY034_08245	COG4177	L-phenylalanine transmembrane transporter activity
FY034_08255	COG0410	ABC transporter
FY034_08285	COG0284	orotidine-5'-phosphate decarboxylase activity
FY034_08290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY034_08295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY034_08305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY034_08310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY034_08315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY034_08320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY034_08325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY034_08330	COG0072	phenylalanine-tRNA ligase activity
FY034_08345	COG0739	heme binding
FY034_08360	COG0174	glutamine synthetase
FY034_08365	COG1994	Peptidase M50
FY034_08370	COG0180	Tryptophanyl-tRNA synthetase
FY034_08375	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY034_08380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY034_08385	COG1355	regulation of microtubule-based process
FY034_08395	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY034_08415	COG3447	MASE1 domain protein
FY034_08415	COG5001	Diguanylate cyclase
FY034_08415	COG5002	protein histidine kinase activity
FY034_08420	COG4191	Histidine kinase
FY034_08430	COG4191	Histidine kinase
FY034_08450	COG2204	response regulator
FY034_08455	COG1100	Small GTP-binding protein
FY034_08475	COG0784	Response regulator, receiver
FY034_08475	COG5002	protein histidine kinase activity
FY034_08480	COG2205	protein histidine kinase activity
FY034_08480	COG2198	Histidine kinase
FY034_08480	COG0784	Response regulator, receiver
FY034_08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY034_08485	COG3437	response regulator, receiver
FY034_08490	COG2202	Pas domain
FY034_08490	COG2205	protein histidine kinase activity
FY034_08495	COG0784	Response regulator, receiver
FY034_08500	COG0784	Response regulator, receiver
FY034_08500	COG2205	protein histidine kinase activity
FY034_08500	COG2198	Histidine kinase
FY034_08505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_08530	COG5001	Diguanylate cyclase
FY034_08530	COG3447	MASE1 domain protein
FY034_08530	COG5002	protein histidine kinase activity
FY034_08535	COG0516	GMP reductase activity
FY034_08535	COG0517	IMP dehydrogenase activity
FY034_08540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY034_08540	COG0519	Catalyzes the synthesis of GMP from XMP
FY034_08545	COG1305	Transglutaminase-like
FY034_08565	COG2116	formate transmembrane transporter activity
FY034_08570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY034_08580	COG0442	prolyl-tRNA aminoacylation
FY034_08585	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FY034_08600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY034_08610	COG1570	exodeoxyribonuclease VII activity
FY034_08615	COG1192	Involved in chromosome partitioning
FY034_08620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY034_08625	COG0776	regulation of translation
FY034_08630	COG2861	carbohydrate metabolic process
FY034_08635	COG0793	Belongs to the peptidase S41A family
FY034_08645	COG2177	Part of the ABC transporter FtsEX involved in
FY034_08650	COG2884	Cell division ATP-binding protein ftsE
FY034_08655	COG1216	Glycosyl transferase, family 2
FY034_08675	COG0776	regulation of translation
FY034_08680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY034_08685	COG0740	serine-type endopeptidase activity
FY034_08690	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY034_08705	COG0494	nUDIX hydrolase
FY034_08710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY034_08715	COG0698	ribose 5-phosphate isomerase
FY034_08720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY034_08725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_08730	COG1028	Short-chain dehydrogenase reductase Sdr
FY034_08735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY034_08740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY034_08745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY034_08750	COG0416	fatty acid biosynthetic process
FY034_08755	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY034_08765	COG1363	Peptidase, m42
FY034_08770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_08775	COG0571	ribonuclease III activity
FY034_08780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY034_08790	COG1774	PSP1 C-terminal conserved region
FY034_08795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY034_08795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY034_08805	COG3123	guanosine phosphorylase activity
FY034_08820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY034_08845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY034_08850	COG1028	Short-chain dehydrogenase reductase Sdr
FY034_08855	COG0028	Belongs to the TPP enzyme family
FY034_08880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY034_08910	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FY034_08915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY034_08920	COG1234	tRNA 3'-trailer cleavage
FY034_08930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY034_08945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_08970	COG3676	manually curated
FY034_08975	COG0583	DNA-binding transcription factor activity
FY034_08995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY034_09000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY034_09015	COG0398	Pfam SNARE associated Golgi protein
FY034_09020	COG2226	methyltransferase
FY034_09030	COG2205	protein histidine kinase activity
FY034_09030	COG3437	response regulator, receiver
FY034_09030	COG4999	Histidine kinase
FY034_09030	COG3850	Histidine kinase
FY034_09055	COG1902	pentaerythritol trinitrate reductase activity
FY034_09060	COG1846	Transcriptional regulator
FY034_09065	COG2353	YceI-like domain
FY034_09075	COG3384	dioxygenase
FY034_09095	COG0542	response to heat
FY034_09125	COG2205	protein histidine kinase activity
FY034_09125	COG2198	Histidine kinase
FY034_09125	COG0784	Response regulator, receiver
FY034_09130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY034_09135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FY034_09135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY034_09145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY034_09150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY034_09155	COG1862	Preprotein translocase
FY034_09160	COG0343	queuine tRNA-ribosyltransferase activity
FY034_09165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY034_09170	COG2385	sporulation resulting in formation of a cellular spore
FY034_09175	COG0444	Belongs to the ABC transporter superfamily
FY034_09180	COG4608	Belongs to the ABC transporter superfamily
FY034_09190	COG0343	queuine tRNA-ribosyltransferase activity
FY034_09200	COG0148	phosphopyruvate hydratase activity
FY034_09205	COG0166	Belongs to the GPI family
FY034_09210	COG1126	abc transporter atp-binding protein
FY034_09215	COG0765	amino acid transport
FY034_09220	COG2208	phosphoserine phosphatase activity
FY034_09220	COG2770	Histidine kinase
FY034_09230	COG0167	dihydroorotate dehydrogenase activity
FY034_09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY034_09265	COG0601	transmembrane transport
FY034_09270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY034_09275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY034_09285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY034_09300	COG1640	4-alpha-glucanotransferase
FY034_09315	COG0714	Associated with various cellular activities
FY034_09330	COG3956	TIGRFAM MazG family protein
FY034_09365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FY034_09370	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FY034_09375	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FY034_09425	COG3829	transcription factor binding
FY034_09425	COG3290	protein histidine kinase activity
FY034_09440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY034_09455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY034_09480	COG0505	Belongs to the CarA family
FY034_09485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY034_09490	COG0540	Belongs to the ATCase OTCase family
FY034_09495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FY034_09500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY034_09510	COG1131	(ABC) transporter
FY034_09540	COG4968	Prepilin-type N-terminal cleavage methylation domain
FY034_09565	COG2208	phosphoserine phosphatase activity
FY034_09580	COG1509	lysine 2,3-aminomutase activity
FY034_09585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY034_09590	COG0741	lytic transglycosylase activity
FY034_09595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY034_09600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY034_09605	COG0268	Binds directly to 16S ribosomal RNA
FY034_09645	COG0495	leucyl-tRNA aminoacylation
FY034_09650	COG2201	protein-glutamate methylesterase activity
FY034_09655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY034_09665	COG0835	chemotaxis
FY034_09670	COG0835	chemotaxis
FY034_09675	COG3267	Type II secretory pathway component ExeA
FY034_09675	COG3409	Peptidoglycan-binding domain 1 protein
FY034_09680	COG0643	Histidine kinase
FY034_09680	COG2198	Histidine kinase
FY034_09685	COG0745	RESPONSE REGULATOR receiver
FY034_09695	COG1160	GTP binding
FY034_09700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY034_09705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY034_09710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_09720	COG0646	methionine synthase
FY034_09720	COG1410	methionine synthase
FY034_09725	COG0326	Molecular chaperone. Has ATPase activity
FY034_09735	COG0539	negative regulation of cytoplasmic translation
FY034_09740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY034_09745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY034_09750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY034_09755	COG0287	Prephenate dehydrogenase
FY034_09760	COG0077	Prephenate dehydratase
FY034_09760	COG1605	Chorismate mutase
FY034_09805	COG3852	Histidine kinase
FY034_09810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FY034_09820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY034_09825	COG1660	Displays ATPase and GTPase activities
FY034_09830	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY034_09840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FY034_09845	COG1137	ATPase activity
FY034_09860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FY034_09870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY034_09875	COG2255	four-way junction helicase activity
FY034_09880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY034_09920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY034_09930	COG1722	exodeoxyribonuclease VII activity
FY034_09935	COG1032	radical SAM domain protein
FY034_09965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY034_09975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY034_09985	COG1032	radical SAM domain protein
FY034_10005	COG1032	radical SAM domain protein
FY034_10010	COG1032	radical SAM domain protein
FY034_10015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_10020	COG1560	Kdo2-lipid A biosynthetic process
FY034_10050	COG1053	succinate dehydrogenase
FY034_10070	COG0492	ferredoxin-NADP+ reductase activity
FY034_10075	COG1011	Hydrolase
FY034_10090	COG1528	Iron-storage protein
FY034_10100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_10105	COG0784	Response regulator, receiver
FY034_10105	COG0835	chemotaxis
FY034_10120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY034_10125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY034_10125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY034_10130	COG0792	nuclease activity
FY034_10140	COG1534	Rna-binding protein
FY034_10145	COG1657	PFAM Prenyltransferase squalene oxidase
FY034_10150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_10155	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY034_10160	COG0535	radical SAM domain protein
FY034_10170	COG0084	hydrolase, TatD family'
FY034_10185	COG0754	glutathionylspermidine amidase activity
FY034_10200	COG2050	protein possibly involved in aromatic compounds catabolism
FY034_10215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY034_10265	COG2205	protein histidine kinase activity
FY034_10265	COG0784	Response regulator, receiver
FY034_10270	COG0011	TIGRFAM Protein of
FY034_10280	COG2070	2-Nitropropane dioxygenase
FY034_10280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY034_10285	COG3321	synthase
FY034_10285	COG1028	Short-chain dehydrogenase reductase Sdr
FY034_10285	COG0604	alcohol dehydrogenase
FY034_10290	COG4221	oxidoreductase activity
FY034_10290	COG1028	Short-chain dehydrogenase reductase Sdr
FY034_10290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY034_10290	COG3321	synthase
FY034_10295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY034_10300	COG0596	Alpha beta hydrolase
FY034_10305	COG0318	PFAM AMP-dependent synthetase and ligase
FY034_10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_10315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY034_10325	COG0785	Cytochrome C biogenesis protein
FY034_10330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY034_10335	COG0142	geranyltranstransferase activity
FY034_10340	COG0513	Belongs to the DEAD box helicase family
FY034_10360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY034_10375	COG1758	RNA polymerase activity
FY034_10380	COG0194	GDP metabolic process
FY034_10385	COG1561	YicC-like family, N-terminal region
FY034_10435	COG1487	ribonuclease activity
FY034_10445	COG3267	Type II secretory pathway component ExeA
FY034_10445	COG3409	Peptidoglycan-binding domain 1 protein
FY034_10460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY034_10465	COG0167	dihydroorotate dehydrogenase activity
FY034_10470	COG0543	2 iron, 2 sulfur cluster binding
FY034_10475	COG0456	acetyltransferase
FY034_10480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY034_10500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FY034_10500	COG0674	pyruvate-flavodoxin oxidoreductase activity
FY034_10515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY034_10520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY034_10525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FY034_10530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY034_10540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY034_10550	COG1216	Glycosyl transferase, family 2
FY034_10575	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY034_10585	COG0705	Rhomboid family
FY034_10595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY034_10620	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY034_10630	COG0537	adenosine 5'-monophosphoramidase activity
FY034_10650	COG0670	Belongs to the BI1 family
FY034_10660	COG3530	Putative quorum-sensing-regulated virulence factor
FY034_10670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY034_10680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_10690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY034_10695	COG0737	Belongs to the 5'-nucleotidase family
FY034_10725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FY034_10735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY034_10750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY034_10755	COG3961	Belongs to the TPP enzyme family
FY034_10760	COG2814	Major facilitator Superfamily
FY034_10830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY034_10840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY034_10845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY034_10855	COG0746	molybdenum cofactor guanylyltransferase activity
FY034_10860	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY034_10860	COG3608	succinylglutamate desuccinylase aspartoacylase
FY034_10885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_10895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_10900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY034_10905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY034_10920	COG2204	response regulator
FY034_10945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY034_10955	COG4191	Histidine kinase
FY034_10990	COG0488	(ABC) transporter
FY034_11030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY034_11035	COG0228	four-way junction DNA binding
FY034_11040	COG1837	Belongs to the UPF0109 family
FY034_11045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY034_11055	COG4752	Belongs to the RNA methyltransferase TrmD family
FY034_11060	COG0335	large ribosomal subunit rRNA binding
FY034_11065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY034_11070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_11080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY034_11095	COG2816	NAD+ diphosphatase activity
FY034_11100	COG3706	GGDEF domain
FY034_11105	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FY034_11110	COG1321	iron dependent repressor
FY034_11120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FY034_11135	COG1597	lipid kinase activity
FY034_11145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY034_11165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY034_11170	COG0653	protein targeting
FY034_11175	COG0772	Belongs to the SEDS family
FY034_11190	COG1792	Involved in formation and maintenance of cell shape
FY034_11195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY034_11200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FY034_11205	COG0616	signal peptide processing
FY034_11215	COG1183	phosphatidylcholine synthase activity
FY034_11220	COG0688	phosphatidylethanolamine metabolic process
FY034_11225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY034_11230	COG0440	acetolactate synthase activity
FY034_11235	COG0028	Belongs to the TPP enzyme family
FY034_11245	COG0129	dihydroxy-acid dehydratase activity
FY034_11250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY034_11260	COG0058	SHG alpha-glucan phosphorylase activity
FY034_11265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY034_11340	COG0205	6-phosphofructokinase activity
FY034_11345	COG0598	Magnesium transport protein CorA
FY034_11350	COG0037	tRNA processing
FY034_11355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY034_11360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY034_11365	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FY034_11370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY034_11375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY034_11380	COG0736	holo-[acyl-carrier-protein] synthase activity
FY034_11385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY034_11385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY034_11395	COG0802	atpase or kinase
FY034_11440	COG0525	valine-tRNA ligase activity
FY034_11460	COG0579	oxidoreductase
FY034_11465	COG0512	Glutamine amidotransferase of anthranilate synthase
FY034_11470	COG2183	response to ionizing radiation
FY034_11480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_11485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY034_11490	COG0835	chemotaxis
FY034_11490	COG0784	Response regulator, receiver
FY034_11495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY034_11515	COG0513	Belongs to the DEAD box helicase family
FY034_11520	COG3260	NADH ubiquinone oxidoreductase 20
FY034_11530	COG0651	ATP synthesis coupled electron transport
FY034_11545	COG0651	ATP synthesis coupled electron transport
FY034_11555	COG0651	ATP synthesis coupled electron transport
FY034_11570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FY034_11620	COG0795	lipopolysaccharide-transporting ATPase activity
FY034_11630	COG2033	superoxide reductase activity
FY034_11635	COG0012	GTP binding
FY034_11640	COG0193	aminoacyl-tRNA hydrolase activity
FY034_11645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY034_11650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY034_11655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY034_11665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY034_11675	COG0436	Aminotransferase
FY034_11685	COG1342	Belongs to the UPF0251 family
FY034_11700	COG0822	iron-sulfur transferase activity
FY034_11710	COG0360	Binds together with S18 to 16S ribosomal RNA
FY034_11715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY034_11725	COG0359	binds to the 23S rRNA
FY034_11730	COG1253	flavin adenine dinucleotide binding
FY034_11740	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FY034_11745	COG1045	serine acetyltransferase
FY034_11750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FY034_11750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FY034_11770	COG0488	(ABC) transporter
FY034_11775	COG0513	Belongs to the DEAD box helicase family
FY034_11800	COG0517	IMP dehydrogenase activity
FY034_11800	COG1227	inorganic diphosphatase activity
FY034_11820	COG1278	Cold shock
FY034_11830	COG2223	nitrite transmembrane transporter activity
FY034_11845	COG3852	Histidine kinase
FY034_11850	COG2204	response regulator
FY034_11865	COG0432	Pfam Uncharacterised protein family UPF0047
FY034_11870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY034_11880	COG0733	neurotransmitter:sodium symporter activity
FY034_11905	COG2233	PERMEase
FY034_11915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY034_11920	COG0095	Lipoate-protein ligase
FY034_11950	COG4106	trans-aconitate 2-methyltransferase activity
FY034_11955	COG0500	methyltransferase
FY034_11965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY034_11970	COG0509	glycine decarboxylation via glycine cleavage system
FY034_11980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY034_11990	COG3437	response regulator, receiver
FY034_11990	COG0784	Response regulator, receiver
FY034_11995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY034_12005	COG0497	DNA recombination
FY034_12010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY034_12030	COG1929	Belongs to the glycerate kinase type-1 family
FY034_12040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY034_12045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY034_12060	COG2239	Acts as a magnesium transporter
FY034_12065	COG1914	H( )-stimulated, divalent metal cation uptake system
FY034_12075	COG4974	Belongs to the 'phage' integrase family
FY034_12090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY034_12090	COG0321	lipoyl(octanoyl) transferase activity
FY034_12095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY034_12100	COG0668	transmembrane transport
FY034_12125	COG0047	phosphoribosylformylglycinamidine synthase activity
FY034_12130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY034_12135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY034_12140	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY034_12145	COG0537	adenosine 5'-monophosphoramidase activity
FY034_12160	COG0052	Belongs to the universal ribosomal protein uS2 family
FY034_12165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY034_12170	COG0528	UMP kinase activity
FY034_12175	COG0233	cytoplasmic translational termination
FY034_12180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY034_12185	COG4589	Belongs to the CDS family
FY034_12190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY034_12195	COG0750	zinc metalloprotease
FY034_12200	COG1214	PFAM Peptidase M22, glycoprotease
FY034_12205	COG0045	succinate-CoA ligase (ADP-forming) activity
FY034_12210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY034_12215	COG0688	phosphatidylethanolamine metabolic process
FY034_12235	COG3437	response regulator, receiver
FY034_12270	COG0825	malonyl-CoA metabolic process
FY034_12275	COG1187	pseudouridine synthase activity
FY034_12280	COG0017	Asparaginyl-tRNA synthetase
FY034_12285	COG1550	Protein conserved in bacteria
FY034_12290	COG1480	7TM receptor with intracellular HD hydrolase
FY034_12295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY034_12305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY034_12315	COG0791	NLP P60 protein
FY034_12335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_12350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FY034_12360	COG0438	transferase activity, transferring glycosyl groups
FY034_12365	COG1215	transferase activity, transferring glycosyl groups
FY034_12370	COG1215	transferase activity, transferring glycosyl groups
FY034_12390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_12405	COG0463	Glycosyl transferase, family 2
FY034_12415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY034_12420	COG1333	cytochrome c biogenesis protein
FY034_12430	COG0151	Belongs to the GarS family
FY034_12435	COG0138	bifunctional purine biosynthesis protein purh
FY034_12445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY034_12450	COG0352	thiamine-phosphate diphosphorylase activity
FY034_12450	COG0351	phosphomethylpyrimidine kinase
FY034_12455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY034_12460	COG0864	Transcriptional regulator
FY034_12470	COG1122	ATPase activity
FY034_12475	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY034_12480	COG0310	cobalt ion transport
FY034_12485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY034_12520	COG0840	transmembrane signaling receptor activity
FY034_12535	COG0328	RNA-DNA hybrid ribonuclease activity
FY034_12545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FY034_12550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY034_12555	COG1193	negative regulation of DNA recombination
FY034_12565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY034_12580	COG3852	Histidine kinase
FY034_12585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY034_12590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_12595	COG0071	Belongs to the small heat shock protein (HSP20) family
FY034_12600	COG3259	Nickel-dependent hydrogenase
FY034_12605	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
FY034_12610	COG3383	formate dehydrogenase (NAD+) activity
FY034_12640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY034_12640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY034_12645	COG1381	Involved in DNA repair and RecF pathway recombination
FY034_12665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FY034_12670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY034_12680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FY034_12685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY034_12700	COG1408	metallophosphoesterase
FY034_12705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FY034_12710	COG0741	lytic transglycosylase activity
FY034_12720	COG0835	chemotaxis
FY034_12725	COG2198	Histidine kinase
FY034_12725	COG0784	Response regulator, receiver
FY034_12725	COG0643	Histidine kinase
FY034_12740	COG2201	protein-glutamate methylesterase activity
FY034_12750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY034_12755	COG2259	Doxx family
FY034_12765	COG0237	dephospho-CoA kinase activity
FY034_12770	COG0116	Belongs to the methyltransferase superfamily
FY034_12770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY034_12780	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FY034_12795	COG2204	response regulator
FY034_12800	COG5002	protein histidine kinase activity
FY034_12820	COG0484	heat shock protein binding
FY034_12825	COG0443	Heat shock 70 kDa protein
FY034_12830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY034_12835	COG1420	regulation of RNA biosynthetic process
FY034_12840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY034_12945	COG4397	Mu-like prophage major head subunit gpT
FY034_12965	COG2369	cell adhesion
FY034_12970	COG4383	Mu-like prophage protein gp29
FY034_12985	COG0640	Transcriptional regulator
FY034_13115	COG2801	Transposase and inactivated derivatives
FY034_13200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY034_13235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY034_13320	COG2801	Transposase and inactivated derivatives
FY034_13355	COG2361	Protein of unknown function DUF86
FY034_13375	COG4206	TonB-dependent receptor
FY034_13385	COG3852	Histidine kinase
FY034_13390	COG2204	response regulator
FY034_13400	COG1024	Enoyl-CoA hydratase
FY034_13415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FY034_13425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY034_13435	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY034_13455	COG4585	Histidine kinase
FY034_13475	COG0628	permease
FY034_13480	COG2217	Heavy metal translocating P-type atpase
FY034_13495	COG5002	protein histidine kinase activity
FY034_13505	COG2198	Histidine kinase
FY034_13505	COG0643	Histidine kinase
FY034_13510	COG0840	transmembrane signaling receptor activity
FY034_13515	COG0835	chemotaxis
FY034_13525	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY034_13530	COG2201	protein-glutamate methylesterase activity
FY034_13535	COG0784	Response regulator, receiver
FY034_13535	COG2205	protein histidine kinase activity
FY034_13535	COG5002	protein histidine kinase activity
FY034_13540	COG0745	RESPONSE REGULATOR receiver
FY034_13550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY034_13555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY034_13560	COG0459	protein refolding
FY034_13580	COG1450	Type ii and iii secretion system protein
FY034_13585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY034_13595	COG3267	Type II secretory pathway component ExeA
FY034_13595	COG3409	Peptidoglycan-binding domain 1 protein
FY034_13610	COG4969	Belongs to the N-Me-Phe pilin family
FY034_13630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY034_13645	COG0745	RESPONSE REGULATOR receiver
FY034_13650	COG2205	protein histidine kinase activity
FY034_13665	COG1959	2 iron, 2 sulfur cluster binding
FY034_13670	COG1606	tRNA processing
FY034_13690	COG2204	response regulator
FY034_13695	COG4191	Histidine kinase
FY034_13710	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FY034_13720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY034_13725	COG0309	Hydrogenase expression formation protein (HypE)
FY034_13735	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY034_13740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY034_13750	COG2205	protein histidine kinase activity
FY034_13750	COG5002	protein histidine kinase activity
FY034_13750	COG0784	Response regulator, receiver
FY034_13765	COG2205	protein histidine kinase activity
FY034_13765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY034_13770	COG1295	ribonuclease BN
FY034_13775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FY034_13790	COG0288	reversible hydration of carbon dioxide
FY034_13795	COG1335	isochorismatase
FY034_13820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FY034_13830	COG1047	Peptidyl-prolyl cis-trans
FY034_13835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY034_13840	COG0348	domain, Protein
FY034_13895	COG0604	alcohol dehydrogenase
FY034_13910	COG3012	SEC-C Motif Domain Protein
FY034_13940	COG0686	Belongs to the AlaDH PNT family
FY034_13945	COG3047	cAMP biosynthetic process
FY034_13965	COG1278	Cold shock
FY034_13975	COG0488	(ABC) transporter
FY034_13985	COG0427	acetyl-CoA hydrolase
FY034_13995	COG0493	'glutamate synthase
FY034_14000	COG0067	glutamate synthase
FY034_14000	COG0069	glutamate synthase activity
FY034_14000	COG0070	glutamate synthase
FY034_14020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY034_14025	COG0513	Belongs to the DEAD box helicase family
FY034_14050	COG2733	membrane
FY034_14060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_14100	COG3300	MHYT domain
FY034_14100	COG5001	Diguanylate cyclase
FY034_14105	COG2195	Cleaves the N-terminal amino acid of tripeptides
FY034_14130	COG0436	Aminotransferase
FY034_14145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY034_14150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY034_14155	COG1611	Belongs to the LOG family
FY034_14160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY034_14165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY034_14180	COG2703	oxygen carrier activity
FY034_14185	COG1067	ATP-dependent peptidase activity
FY034_14200	COG2226	methyltransferase
FY034_14205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FY034_14210	COG0791	NLP P60 protein
FY034_14210	COG1388	LysM domain
FY034_14215	COG1032	radical SAM domain protein
FY034_14245	COG0409	Hydrogenase expression formation protein
FY034_14250	COG0298	carbon dioxide binding
FY034_14255	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FY034_14265	COG1132	(ABC) transporter
FY034_14270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY034_14280	COG0626	cystathionine gamma-synthase activity
FY034_14285	COG0626	cystathionine gamma-synthase activity
FY034_14290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FY034_14295	COG0482	sulfurtransferase activity
FY034_14300	COG4191	Histidine kinase
FY034_14310	COG1410	methionine synthase
FY034_14310	COG0646	methionine synthase
FY034_14315	COG2204	response regulator
FY034_14325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_14330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY034_14350	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY034_14390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_14395	COG3394	polysaccharide catabolic process
FY034_14405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY034_14420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY034_14435	COG0726	polysaccharide deacetylase
FY034_14445	COG1414	Transcriptional regulator
FY034_14455	COG0842	Transport permease protein
FY034_14460	COG0842	Transport permease protein
FY034_14465	COG1131	(ABC) transporter
FY034_14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_14485	COG0330	HflC and HflK could
FY034_14490	COG0590	tRNA wobble adenosine to inosine editing
FY034_14510	COG0535	radical SAM domain protein
FY034_14520	COG1100	Small GTP-binding protein
FY034_14540	COG1007	ATP synthesis coupled electron transport
FY034_14555	COG0713	ATP synthesis coupled electron transport
FY034_14565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY034_14570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY034_14585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY034_14590	COG0649	NAD binding
FY034_14595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY034_14600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY034_14605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY034_14610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY034_14625	COG0356	it plays a direct role in the translocation of protons across the membrane
FY034_14630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY034_14640	COG0165	Argininosuccinate lyase
FY034_14650	COG0494	nUDIX hydrolase
FY034_14655	COG0137	argininosuccinate synthase activity
FY034_14660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY034_14665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY034_14675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY034_14680	COG2205	protein histidine kinase activity
FY034_14685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY034_14710	COG2137	regulation of response to DNA damage stimulus
FY034_14720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY034_14725	COG1058	Belongs to the CinA family
FY034_14725	COG1546	Belongs to the CinA family
FY034_14730	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FY034_14735	COG1691	(AIR) carboxylase
FY034_14740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY034_14750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_14755	COG1242	4 iron, 4 sulfur cluster binding
FY034_14760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY034_14765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY034_14770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY034_14775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY034_14780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY034_14785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY034_14795	COG1475	DNA binding
FY034_14800	COG1192	Involved in chromosome partitioning
FY034_14810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FY034_14820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY034_14825	COG1127	ABC transporter
FY034_14840	COG2854	intermembrane phospholipid transfer
FY034_14850	COG1032	radical SAM domain protein
FY034_14855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY034_14860	COG0628	permease
FY034_14865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY034_14870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY034_14875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY034_14880	COG0154	amidase activity
FY034_14885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY034_14890	COG2201	protein-glutamate methylesterase activity
FY034_14895	COG2198	Histidine kinase
FY034_14895	COG0643	Histidine kinase
FY034_14900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY034_14905	COG1666	GTP binding
FY034_14930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_14940	COG0297	glycogen (starch) synthase activity
FY034_14980	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FY034_14985	COG3447	MASE1 domain protein
FY034_14985	COG5001	Diguanylate cyclase
FY034_14985	COG5002	protein histidine kinase activity
FY034_15005	COG1418	mRNA catabolic process
FY034_15015	COG0242	peptide deformylase activity
FY034_15020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY034_15050	COG3158	transport of potassium into the cell
FY034_15055	COG0745	RESPONSE REGULATOR receiver
FY034_15060	COG2205	protein histidine kinase activity
FY034_15065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY034_15070	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY034_15075	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY034_15085	COG0726	polysaccharide deacetylase
FY034_15095	COG3876	Protein conserved in bacteria
FY034_15100	COG2843	Capsule synthesis protein
FY034_15105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY034_15125	COG0671	phosphoesterase, PA-phosphatase related
FY034_15160	COG0642	Histidine kinase
FY034_15180	COG2814	Major facilitator Superfamily
FY034_15185	COG2996	Protein conserved in bacteria
FY034_15195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FY034_15195	COG3008	intermembrane lipid transfer
FY034_15200	COG2995	paraquat-inducible protein a
FY034_15205	COG2995	paraquat-inducible protein a
FY034_15210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY034_15230	COG0436	Aminotransferase
FY034_15250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY034_15255	COG0124	histidyl-tRNA synthetase
FY034_15270	COG0346	lactoylglutathione lyase activity
FY034_15275	COG1703	isobutyryl-CoA mutase activity
FY034_15280	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY034_15280	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY034_15285	COG0439	Biotin carboxylase
FY034_15290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY034_15300	COG0247	lactate metabolic process
FY034_15305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY034_15310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY034_15315	COG0758	DNA mediated transformation
FY034_15315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY034_15330	COG0826	peptidase U32
FY034_15335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY034_15340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FY034_15345	COG0305	Participates in initiation and elongation during chromosome replication
FY034_15370	COG1706	bacterial-type flagellum-dependent cell motility
FY034_15375	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY034_15390	COG4786	Flagellar basal body rod
FY034_15405	COG1419	protein localization to endoplasmic reticulum
FY034_15410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY034_15415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY034_15430	COG1338	Plays a role in the flagellum-specific transport system
FY034_15455	COG4786	Flagellar basal body rod
FY034_15485	COG1157	protein secretion by the type III secretion system
FY034_15495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY034_15500	COG1766	The M ring may be actively involved in energy transduction
FY034_15505	COG1677	Flagellar hook-basal body complex protein FliE
FY034_15515	COG1815	bacterial-type flagellum-dependent cell motility
FY034_15535	COG0745	RESPONSE REGULATOR receiver
FY034_15550	COG2201	protein-glutamate methylesterase activity
FY034_15565	COG0643	Histidine kinase
FY034_15565	COG2198	Histidine kinase
FY034_15575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY034_15580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY034_15600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FY034_15605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY034_15630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY034_15630	COG0321	lipoyl(octanoyl) transferase activity
FY034_15655	COG3290	protein histidine kinase activity
FY034_15655	COG0840	transmembrane signaling receptor activity
FY034_15660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY034_15675	COG1573	uracil-dna glycosylase
FY034_15685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY034_15690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY034_15705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY034_15715	COG0437	4 iron, 4 sulfur cluster binding
FY034_15730	COG0492	ferredoxin-NADP+ reductase activity
FY034_15785	COG4106	trans-aconitate 2-methyltransferase activity
FY034_15795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_15805	COG1442	glycosyl transferase family 8
FY034_15835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY034_15840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY034_15850	COG5443	negative regulation of bacterial-type flagellum assembly
FY034_15865	COG0463	Glycosyl transferase, family 2
FY034_15865	COG1216	Glycosyl transferase, family 2
FY034_15885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FY034_15900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY034_15915	COG0367	asparagine synthase
FY034_15945	COG3852	Histidine kinase
FY034_15955	COG1132	(ABC) transporter
FY034_15960	COG2084	Dehydrogenase
FY034_15965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY034_15970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY034_15980	COG0864	Transcriptional regulator
FY034_16010	COG0629	single-stranded DNA binding
FY034_16030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FY034_16035	COG0318	PFAM AMP-dependent synthetase and ligase
FY034_16045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY034_16055	COG2814	Major facilitator Superfamily
FY034_16060	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY034_16065	COG0842	Transport permease protein
FY034_16070	COG1129	ABC transporter
FY034_16070	COG0842	Transport permease protein
FY034_16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_16085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY034_16105	COG0463	Glycosyl transferase, family 2
FY034_16115	COG1309	transcriptional regulator
FY034_16130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY034_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_16140	COG1309	transcriptional regulator
FY034_16150	COG1360	Flagellar Motor Protein
FY034_16155	COG1217	gtp-binding protein TYPA
FY034_16160	COG3706	GGDEF domain
FY034_16170	COG0556	nucleotide-excision repair
FY034_16200	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY034_16205	COG1489	DNA binding
FY034_16220	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY034_16225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY034_16230	COG0084	hydrolase, TatD family'
FY034_16250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FY034_16265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY034_16275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_16285	COG2885	chlorophyll binding
FY034_16290	COG0823	Involved in the tonB-independent uptake of proteins
FY034_16305	COG0811	peptide transport
FY034_16310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY034_16315	COG1674	ftsk spoiiie
FY034_16330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FY034_16335	COG0037	tRNA processing
FY034_16340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY034_16345	COG0745	RESPONSE REGULATOR receiver
FY034_16350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY034_16365	COG1196	nuclear chromosome segregation
FY034_16375	COG0552	protein localization to endoplasmic reticulum
FY034_16390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FY034_16400	COG1692	metallophosphoesterase
FY034_16405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY034_16420	COG0688	phosphatidylethanolamine metabolic process
FY034_16435	COG4974	Belongs to the 'phage' integrase family
FY034_16445	COG4988	ABC transporter
FY034_16450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY034_16455	COG1950	PFAM Membrane protein of
FY034_16460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FY034_16475	COG0488	(ABC) transporter
FY034_16480	COG4628	conserved protein (DUF2132)
FY034_16485	COG0513	Belongs to the DEAD box helicase family
FY034_16490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY034_16490	COG4191	Histidine kinase
FY034_16500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY034_16505	COG1335	isochorismatase
FY034_16515	COG0667	Aldo Keto reductase
FY034_16520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY034_16525	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY034_16525	COG3608	succinylglutamate desuccinylase aspartoacylase
FY034_16540	COG2885	chlorophyll binding
FY034_16555	COG1979	alcohol dehydrogenase
FY034_16560	COG2207	Transcriptional regulator
FY034_16570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY034_16600	COG3604	Transcriptional regulator
FY034_16605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FY034_16610	COG1053	succinate dehydrogenase
FY034_16615	COG3275	phosphorelay sensor kinase activity
FY034_16625	COG1304	FMN binding
FY034_16630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY034_16635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_16650	COG0243	molybdopterin cofactor binding
FY034_16655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_16665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FY034_16670	COG2161	toxin-antitoxin pair type II binding
FY034_16675	COG4115	mRNA cleavage
FY034_16690	COG3550	peptidyl-serine autophosphorylation
FY034_16705	COG2204	response regulator
FY034_16715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY034_16725	COG4206	TonB-dependent receptor
FY034_16730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY034_16735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY034_16740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY034_16750	COG2176	DNA-directed DNA polymerase activity
FY034_16750	COG5002	protein histidine kinase activity
FY034_16750	COG2176	DNA-directed DNA polymerase activity
FY034_16750	COG5002	protein histidine kinase activity
FY034_16755	COG4681	YaeQ
FY034_16760	COG3089	Belongs to the UPF0270 family
FY034_16765	COG0534	Mate efflux family protein
FY034_16770	COG0784	Response regulator, receiver
FY034_16775	COG3706	GGDEF domain
FY034_16780	COG4251	negative regulation of phosphorylation
FY034_16785	COG2132	Multicopper oxidase
FY034_16790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY034_16790	COG0574	Belongs to the PEP-utilizing enzyme family
FY034_16810	COG1403	HNH endonuclease
FY034_16815	COG0745	RESPONSE REGULATOR receiver
FY034_16820	COG1136	(ABC) transporter
FY034_16820	COG0577	efflux transmembrane transporter activity
FY034_16840	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FY034_16845	COG0714	Associated with various cellular activities
FY034_16875	COG1714	RDD family
FY034_16880	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FY034_16885	COG0303	'Molybdopterin
FY034_16890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY034_16910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY034_16915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY034_16920	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY034_16925	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FY034_16935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY034_16940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY034_16950	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FY034_16955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY034_16960	COG1002	Type II restriction enzyme, methylase subunits
FY034_16970	COG3645	SOS response
FY034_16975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY034_16985	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FY034_16990	COG0745	RESPONSE REGULATOR receiver
FY034_16995	COG5002	protein histidine kinase activity
FY034_17000	COG0589	response to stress
FY034_17005	COG2204	response regulator
FY034_17025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY034_17030	COG2199	diguanylate cyclase activity
FY034_17040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY034_17045	COG0105	UTP biosynthetic process
FY034_17050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY034_17050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY034_17055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY034_17070	COG0612	Peptidase, M16
FY034_17080	COG5002	protein histidine kinase activity
FY034_17095	COG1199	ATP-dependent helicase activity
FY034_17100	COG0488	(ABC) transporter
FY034_17105	COG1136	(ABC) transporter
FY034_17105	COG4591	ABC-type transport system involved in lipoprotein release permease component
FY034_17110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY034_17115	COG0799	negative regulation of ribosome biogenesis
FY034_17120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY034_17125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_17125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY034_17130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY034_17130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY034_17140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY034_17145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FY034_17150	COG0824	Thioesterase
FY034_17155	COG0357	Ribosomal RNA small subunit methyltransferase G
FY034_17160	COG0445	tRNA wobble uridine modification
FY034_17165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY034_17170	COG0706	membrane insertase activity
FY034_17175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY034_17180	COG0594	ribonuclease P activity
FY034_17185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY034_17265	COG5001	Diguanylate cyclase
FY034_17270	COG0745	RESPONSE REGULATOR receiver
FY034_17330	COG0210	DNA helicase
FY034_17340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY034_17365	COG0557	exoribonuclease II activity
FY034_17470	COG0210	DNA helicase
FY034_17490	COG1278	Cold shock
FY034_17515	COG4095	Psort location CytoplasmicMembrane, score
FY034_17525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FY034_17525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY034_17555	COG0629	single-stranded DNA binding
FY034_17565	COG2176	DNA-directed DNA polymerase activity
FY034_17615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY034_17650	COG3676	manually curated
FY034_17660	COG0776	regulation of translation
FY034_17675	COG1192	Involved in chromosome partitioning
FY034_17685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY034_17705	COG0305	Participates in initiation and elongation during chromosome replication
FY034_17705	COG1372	Participates in initiation and elongation during chromosome replication
FY034_17715	COG1573	uracil-dna glycosylase
FY034_17720	COG3676	manually curated
FY034_17735	COG1104	cysteine desulfurase activity
FY034_17795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY034_17855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY034_17990	COG1690	Belongs to the RtcB family
FY034_18005	COG0202	RNA polymerase activity
FY034_18140	COG2885	chlorophyll binding
FY034_18180	COG3108	Peptidase M15
FY034_18210	COG0210	DNA helicase
FY034_18225	COG4115	mRNA cleavage
FY034_18230	COG2161	toxin-antitoxin pair type II binding
FY034_18245	COG2096	Adenosyltransferase
FY034_18275	COG0189	ligase activity
FY034_18295	COG4115	mRNA cleavage
FY034_18300	COG2161	toxin-antitoxin pair type II binding
FY034_18315	COG3838	Conjugal transfer protein Trbc
FY034_18320	COG4962	Type ii secretion system protein e
FY034_18345	COG0805	protein transport
FY034_18350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_18355	COG2226	methyltransferase
FY034_18365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_18375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_18375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY034_18380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_18415	COG1733	regulation of RNA biosynthetic process
FY034_18460	COG1921	L-seryl-tRNASec selenium transferase activity
FY034_18465	COG2186	Transcriptional regulator
FY034_18490	COG3620	sequence-specific DNA binding
FY034_18490	COG0617	tRNA 3'-terminal CCA addition
FY034_18490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY034_18495	COG2814	Major facilitator Superfamily
FY034_18515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY034_18545	COG1733	regulation of RNA biosynthetic process
FY034_18580	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY034_18595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY034_18615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY034_18630	COG1561	YicC-like family, N-terminal region
FY034_18635	COG0194	GDP metabolic process
FY034_18640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY034_18645	COG1477	protein flavinylation
FY034_18660	COG4115	mRNA cleavage
FY034_18665	COG2161	toxin-antitoxin pair type II binding
FY034_18670	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FY034_18725	COG3335	DDE superfamily endonuclease
FY034_18730	COG1657	PFAM Prenyltransferase squalene oxidase
FY034_18745	COG0784	Response regulator, receiver
FY034_18745	COG2205	protein histidine kinase activity
FY034_18745	COG5002	protein histidine kinase activity
FY034_18905	COG2197	response regulator
FY034_18910	COG4585	Histidine kinase
FY034_18920	COG0670	Belongs to the BI1 family
FY034_18925	COG4974	Belongs to the 'phage' integrase family
FY034_18950	COG0776	regulation of translation
FY034_18995	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates