locus-tag class description GSQ19_00010 ENOG4108IQK o-acetylhomoserine GSQ19_00015 ENOG41066VF YeeE YedE family protein GSQ19_00020 ENOG4105KHC sulfurtransferase GSQ19_00065 ENOG4105BZU Histidine kinase GSQ19_00115 ENOG4107S1Q Phosphatase GSQ19_00170 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GSQ19_00185 ENOG4108JA1 polyketide synthase GSQ19_00195 ENOG4108HMN Caspase domain GSQ19_00205 ENOG4108V1U phospholipid-binding protein GSQ19_00215 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) GSQ19_00225 ENOG4107RA9 decarboxylase GSQ19_00230 ENOG4105D82 Glutamate dehydrogenase GSQ19_00265 ENOG4108NSV This is one of the two reaction center proteins of photosystem II GSQ19_00275 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GSQ19_00310 ENOG4105DGI Alkaline phosphatase GSQ19_00340 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_00350 ENOG4105E2Y ABC, transporter GSQ19_00355 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component GSQ19_00360 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_00365 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) GSQ19_00370 ENOG4105CPU Monooxygenase GSQ19_00385 ENOG4105CPC Aldo Keto reductase GSQ19_00390 ENOG4105GVF (ABC) transporter GSQ19_00400 ENOG4107UWC ABC, transporter GSQ19_00430 ENOG4108DBC nitroreductase GSQ19_00435 ENOG4105GVF (ABC) transporter GSQ19_00440 ENOG4105C28 cystathionine GSQ19_00490 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSQ19_00520 ENOG4105DFS Conserved Protein GSQ19_00555 ENOG4105DYN CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) GSQ19_00560 ENOG41066GP CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity) GSQ19_00580 ENOG4105D5K Hemolysin activator protein GSQ19_00620 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) GSQ19_00670 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) GSQ19_00685 ENOG4107YZX Universal stress protein GSQ19_00690 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) GSQ19_00695 ENOG41084H8 Binds directly to 16S ribosomal RNA (By similarity) GSQ19_00710 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GSQ19_00715 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GSQ19_00720 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GSQ19_00740 ENOG4105CXI aluminum resistance protein GSQ19_00745 ENOG4106I2R Coenzyme F420 hydrogenase dehydrogenase, beta GSQ19_00750 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) GSQ19_00755 ENOG4105Q36 FHA domain containing protein GSQ19_00790 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) GSQ19_00805 ENOG4108JJA ABC, transporter GSQ19_00810 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin GSQ19_00820 ENOG4107GBW cellulosome anchoring protein cohesin GSQ19_00830 ENOG4105CJ1 ABC, transporter GSQ19_00855 ENOG4105C59 p-type ATPase GSQ19_00865 ENOG4107SWG transcriptional regulator MERR family GSQ19_00870 ENOG4105C5I Dehydrogenase GSQ19_00875 ENOG4105E6M Sulphatase-modifying factor protein GSQ19_00880 ENOG41061MV Arylsulfatase GSQ19_00900 ENOG4105CGC Nitrogenase cofactor biosynthesis protein NifB GSQ19_00905 ENOG4105C3J Cysteine desulfurase GSQ19_00920 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) GSQ19_00930 ENOG4105CY9 nitrogenase molybdenum-iron protein beta chain GSQ19_00940 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_00945 ENOG4108UR2 Nitrogen fixation protein NifX GSQ19_00950 ENOG4108VQE nitrogen fixation protein GSQ19_00955 ENOG4105X87 nitrogen fixation GSQ19_00960 ENOG4106C8Q May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity) GSQ19_00965 ENOG41081QJ UBA THIF-type NAD FAD binding GSQ19_00970 ENOG4108Z4V iron-sulfur cluster assembly GSQ19_00980 ENOG4105WCA Ferredoxin GSQ19_01010 ENOG4107QRI Phosphoketolase GSQ19_01070 ENOG4108JYK Dehydrogenase GSQ19_01095 ENOG4105E46 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process GSQ19_01100 ENOG41067HS methyltransferase GSQ19_01130 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_01150 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) GSQ19_01160 ENOG4108UXN response regulator GSQ19_01170 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) GSQ19_01210 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) GSQ19_01235 ENOG4105N7N Pentapeptide repeat-containing protein GSQ19_01240 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit GSQ19_01255 ENOG4105C1V Peptidase, M16 GSQ19_01265 ENOG41086DT Membrane protein of unknown function GSQ19_01305 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) GSQ19_01315 ENOG4105NAE bifunctional deaminase-reductase domain protein GSQ19_01320 ENOG4105VPX protein, conserved in bacteria GSQ19_01335 ENOG4105BZU Histidine kinase GSQ19_01340 ENOG4105ES5 Histidine kinase GSQ19_01355 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr GSQ19_01365 ENOG4105CPU Monooxygenase GSQ19_01380 ENOG4107XGZ Hydrolase GSQ19_01390 ENOG4105CIH Imidazole acetol-phosphate transaminase GSQ19_01395 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) GSQ19_01425 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit GSQ19_01455 ENOG4105BZ1 (ABC) transporter GSQ19_01470 ENOG4105BZU Histidine kinase GSQ19_01470 ENOG4105BZU Histidine kinase GSQ19_01475 ENOG4107WMZ Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) GSQ19_01485 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSQ19_01495 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) GSQ19_01520 ENOG4105VCC 30S ribosomal protein S21 GSQ19_01530 ENOG41082B1 30S ribosomal protein S16 GSQ19_01545 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein GSQ19_01550 ENOG4105C32 Amino acid ABC transporter (Permease) GSQ19_01560 ENOG4105C0Z ABC transporter GSQ19_01565 ENOG4108IV0 ABC, transporter GSQ19_01570 ENOG4107RAQ aminopeptidase GSQ19_01575 ENOG4107TIF Phenazine biosynthesis protein, PhzF family GSQ19_01595 ENOG4105C1V Peptidase, M16 GSQ19_01650 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) GSQ19_01670 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) GSQ19_01675 ENOG4105D49 3-dehydroquinate synthase GSQ19_01690 ENOG4107QSQ Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) GSQ19_01700 ENOG4105D9P serine threonine protein kinase GSQ19_01750 ENOG4105BZU Histidine kinase GSQ19_01785 ENOG4107RNB anthranilate phosphoribosyltransferase GSQ19_01795 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain GSQ19_01800 ENOG41082AN stage II sporulation protein GSQ19_01820 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) GSQ19_01825 ENOG4107Z8Z Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) GSQ19_01865 ENOG4105DPV During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction GSQ19_01870 ENOG41084UD rubredoxin GSQ19_01875 ENOG4105BZU Histidine kinase GSQ19_01880 ENOG4105D5K Hemolysin activator protein GSQ19_01885 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein GSQ19_01905 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_01910 ENOG4105BZU Histidine kinase GSQ19_01915 ENOG4105BZU Histidine kinase GSQ19_01925 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSQ19_01945 ENOG4105FAV ABC, transporter GSQ19_01955 ENOG4105FDK ABC transporter GSQ19_01960 ENOG4105DSE periplasmic solute binding protein GSQ19_01965 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_02000 ENOG410848W 30S ribosomal protein S21 GSQ19_02005 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) GSQ19_02010 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GSQ19_02015 ENOG4105WIA photosystem II reaction center protein H GSQ19_02020 ENOG410686T photosystem II reaction center protein N GSQ19_02040 ENOG4105E5G Alpha beta hydrolase fold GSQ19_02055 ENOG4105BZU Histidine kinase GSQ19_02085 ENOG4107U7Q Transfers the fatty acyl group on membrane lipoproteins (By similarity) GSQ19_02100 ENOG4105DUM transcriptional regulator, lysR family GSQ19_02110 ENOG4105MN7 Carbon dioxide concentrating mechanism protein GSQ19_02120 ENOG4105MXK Carbon dioxide concentrating mechanism protein GSQ19_02130 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml GSQ19_02135 ENOG4108WT6 Carbon dioxide concentrating mechanism protein GSQ19_02145 ENOG4105D65 subunit l GSQ19_02150 ENOG4105C8S subunit m GSQ19_02165 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) GSQ19_02180 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 GSQ19_02195 ENOG4105DGW oligopeptidase A GSQ19_02210 ENOG4106DDF Photosystem II reaction center protein M GSQ19_02220 ENOG4107JEG This protein is a component of the reaction center of photosystem II (By similarity) GSQ19_02225 ENOG4105D9P serine threonine protein kinase GSQ19_02235 ENOG4105E66 phosphoriboisomerase A GSQ19_02260 ENOG4108Z0Z intracellular protease Pfpi family GSQ19_02300 ENOG4105D9P serine threonine protein kinase GSQ19_02310 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GSQ19_02315 ENOG4105KHC sulfurtransferase GSQ19_02320 ENOG4105DFS Conserved Protein GSQ19_02325 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) GSQ19_02335 ENOG4105DX0 Hemolysin A GSQ19_02340 ENOG4108UMY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSQ19_02345 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSQ19_02350 ENOG4105E2Z phosphate ABC transporter (Permease GSQ19_02355 ENOG4105C8U phosphate abc transporter GSQ19_02360 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) GSQ19_02365 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) GSQ19_02370 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_02440 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) GSQ19_02450 ENOG4108I0Q anthranilate phosphoribosyltransferase GSQ19_02455 ENOG4105F04 LysR family Transcriptional regulator GSQ19_02460 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_02480 ENOG4105I5W Transporter GSQ19_02495 ENOG4105D7T ABC transporter GSQ19_02500 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) GSQ19_02525 ENOG4108P5B Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) GSQ19_02545 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) GSQ19_02555 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) GSQ19_02560 ENOG4105CQB FAD linked oxidase domain protein GSQ19_02645 ENOG4105BZ1 (ABC) transporter GSQ19_02670 ENOG4108R9R May be involved in photosynthetic membrane biogenesis (By similarity) GSQ19_02675 ENOG4105D7V transposase GSQ19_02680 ENOG4108YH8 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) GSQ19_02690 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) GSQ19_02705 ENOG4105CNI cell division protein FtsW GSQ19_02725 ENOG4108IAJ Nad-dependent epimerase dehydratase GSQ19_02730 ENOG4105C6Y Udp-glucose 6-dehydrogenase GSQ19_02735 ENOG4108Z66 YbaK ebsC protein GSQ19_02755 ENOG4105DPX Hydrogenase, large subunit GSQ19_02790 ENOG4105C8H hydrogenase maturation protein Hypf GSQ19_02795 ENOG41082MF Hydrogenase assembly chaperone hypC hupF GSQ19_02800 ENOG4105CQS hydrogenase expression formation protein HypD GSQ19_02810 ENOG4105C45 hydrogenase expression formation protein (HypE) GSQ19_02815 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) GSQ19_02820 ENOG4107RSS Hydrogenase accessory protein HypB GSQ19_02840 ENOG4107SCA Formamidase (EC 3.5.1.49) GSQ19_02840 ENOG4107SCA Formamidase (EC 3.5.1.49) GSQ19_02860 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) GSQ19_02880 ENOG4105CJN penicillin-binding protein GSQ19_02905 ENOG4105C3G gtp-binding protein GSQ19_02925 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) GSQ19_02930 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) GSQ19_02935 ENOG4105BZU Histidine kinase GSQ19_02950 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) GSQ19_02955 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) GSQ19_02965 ENOG4105C3M thioredoxin reductase GSQ19_02980 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) GSQ19_02990 ENOG4105EPW hflc protein GSQ19_02995 ENOG4105VFU Rna-binding protein GSQ19_03000 ENOG410848W 30S ribosomal protein S21 GSQ19_03005 ENOG4105XUP Phage derived protein Gp49-like (DUF891) GSQ19_03010 ENOG4105F8J Adenylate Guanylate cyclase GSQ19_03020 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) GSQ19_03030 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase GSQ19_03040 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) GSQ19_03055 ENOG4107QIZ NADH dehydrogenase GSQ19_03070 ENOG4108IEH NADH dehydrogenase subunit g GSQ19_03080 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_03105 ENOG4105CD5 CoA-binding domain protein GSQ19_03120 ENOG4105EMU Dehydrogenase GSQ19_03175 ENOG4105XEV csbD-like GSQ19_03185 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) GSQ19_03250 ENOG4105CYM Glutathione S-transferase GSQ19_03265 ENOG4105BZU Histidine kinase GSQ19_03275 ENOG4105F8J Adenylate Guanylate cyclase GSQ19_03280 ENOG4107SBE Glycosyl transferase (Group 1 GSQ19_03290 ENOG4105BZU Histidine kinase GSQ19_03295 ENOG4105BZU Histidine kinase GSQ19_03315 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) GSQ19_03325 ENOG4108MUZ hydrolase GSQ19_03350 ENOG4107Z6A sulfate abc transporter permease GSQ19_03355 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GSQ19_03360 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GSQ19_03385 ENOG4105E7A Glutamine amidotransferase GSQ19_03395 ENOG4108XKD photosystem i GSQ19_03400 ENOG4105BZU Histidine kinase GSQ19_03420 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GSQ19_03455 ENOG4105BZS acriflavin resistance protein GSQ19_03480 ENOG4105SUT Transcriptional Regulator AraC Family GSQ19_03485 ENOG4107SQU synthase GSQ19_03490 ENOG4107EEY synthase GSQ19_03495 ENOG4108JA1 polyketide synthase GSQ19_03505 ENOG4108JA1 polyketide synthase GSQ19_03525 ENOG4107QKG PfaD family GSQ19_03540 ENOG4108ZAF Molybdopterin GSQ19_03550 ENOG4108K5P (LipO)protein GSQ19_03560 ENOG4105CHR reductase GSQ19_03565 ENOG4108TVJ Nitroreductase GSQ19_03570 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSQ19_03575 ENOG4105K63 Thioredoxin GSQ19_03580 ENOG4105YVS arsR family transcriptional regulator GSQ19_03640 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) GSQ19_03645 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) GSQ19_03650 ENOG41066AK Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity) GSQ19_03665 ENOG4105BZU Histidine kinase GSQ19_03670 ENOG4105CHR reductase GSQ19_03675 ENOG4105BZU Histidine kinase GSQ19_03680 ENOG4107Z5C methylesterase GSQ19_03685 ENOG4105BZU Histidine kinase GSQ19_03690 ENOG4107YD0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) GSQ19_03700 ENOG4105MKQ Monovalent cation H antiporter subunit C GSQ19_03705 ENOG4108JPZ Monovalent cation H antiporter subunit D GSQ19_03765 ENOG4108ZJ4 polysaccharide deacetylase GSQ19_03780 ENOG41083KH UPF0102 protein GSQ19_03790 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) GSQ19_03800 ENOG4107ZYR domain protein GSQ19_03805 ENOG4105CZN Potassium uptake protein GSQ19_03840 ENOG4105MYT Heat shock protein GSQ19_03865 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) GSQ19_03920 ENOG4108IJ9 (ABC) transporter GSQ19_03930 ENOG4108HMX isocitrate dehydrogenase (NADP) GSQ19_03940 ENOG4105D3Q Sugar transferase GSQ19_03960 ENOG4105FAT Acyl-transferase GSQ19_03985 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_03990 ENOG4105VFN O-Antigen polymerase GSQ19_03995 ENOG4105CGN Glycosyl transferase (Group 1 GSQ19_04000 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family GSQ19_04015 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) GSQ19_04060 ENOG4107QI6 Cysteine desulfurase GSQ19_04070 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family GSQ19_04075 ENOG4105PW4 Sugar fermentation stimulation protein homolog GSQ19_04085 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) GSQ19_04115 ENOG4105C9B Cysteine desulfurase GSQ19_04130 ENOG4105MZG transcriptional modulator of maze toxin, mazf GSQ19_04165 ENOG4105EGD dinuclear metal center protein, YbgI family GSQ19_04215 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) GSQ19_04220 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) GSQ19_04230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_04235 ENOG4105CRQ synthase (Component I) GSQ19_04250 ENOG4105DK0 Indole-3-glycerol phosphate synthase GSQ19_04270 ENOG4108UXN response regulator GSQ19_04275 ENOG4105EHG Permease protein GSQ19_04285 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP GSQ19_04320 ENOG4105CHR reductase GSQ19_04325 ENOG4105WQ3 Rna-binding protein GSQ19_04360 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_04375 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase GSQ19_04385 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase GSQ19_04410 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) GSQ19_04415 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A GSQ19_04420 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase GSQ19_04425 ENOG4105BZU Histidine kinase GSQ19_04430 ENOG4105E4C Lytic transglycosylase catalytic GSQ19_04440 ENOG4108PXI ErfK YbiS YcfS YnhG GSQ19_04450 ENOG4105EMN RNA polymerase sigma factor GSQ19_04465 ENOG4105C8T Leucyl-tRNA synthetase GSQ19_04470 ENOG4108Z6B deaminase GSQ19_04545 ENOG4105FBB Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity) GSQ19_04595 ENOG4105D05 Receptor GSQ19_04620 ENOG4105D7V transposase GSQ19_04650 ENOG4105QYV Membrane GSQ19_04665 ENOG4105EHV domain protein GSQ19_04675 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) GSQ19_04695 ENOG4108JJB ABC transporter GSQ19_04725 ENOG4108JQ6 ABC transporter GSQ19_04735 ENOG4105BZ1 (ABC) transporter GSQ19_04750 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) GSQ19_04760 ENOG4107MKT Stringent starvation protein a GSQ19_04770 ENOG4107QZT geranylgeranyl reductase GSQ19_04780 ENOG4105GVF (ABC) transporter GSQ19_04785 ENOG4105GVF (ABC) transporter GSQ19_04800 ENOG4107MKT Stringent starvation protein a GSQ19_04820 ENOG4105CPC Aldo Keto reductase GSQ19_04825 ENOG4107MKT Stringent starvation protein a GSQ19_04835 ENOG4105GVF (ABC) transporter GSQ19_04855 ENOG4105FBW Monooxygenase GSQ19_04895 ENOG4105DUM transcriptional regulator, lysR family GSQ19_04905 ENOG4107TSN permease GSQ19_04910 ENOG410841Q phosphoesterase PA-phosphatase related protein GSQ19_04920 ENOG4105EPW hflc protein GSQ19_04935 ENOG4105CNF WD-40 repeat protein GSQ19_04940 ENOG4105CHJ isochorismatase hydrolase GSQ19_04945 ENOG4108ZFD Antibiotic biosynthesis monooxygenase GSQ19_04960 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) GSQ19_05010 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) GSQ19_05055 ENOG4105D38 putrescine abc transporter GSQ19_05070 ENOG4105E2K Glycosyl transferase (Group 1 GSQ19_05075 ENOG4105C5R Aminotransferase GSQ19_05085 ENOG41081FY multiple antibiotic resistance (MarC)-related GSQ19_05105 ENOG4105C59 p-type ATPase GSQ19_05120 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) GSQ19_05130 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) GSQ19_05135 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) GSQ19_05140 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSQ19_05150 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) GSQ19_05210 ENOG4105CHM Aminotransferase GSQ19_05215 ENOG4107YCR Transcriptional regulator, ARSR family GSQ19_05230 ENOG4105DWF phosphomethylpyrimidine kinase GSQ19_05235 ENOG4105CKK Glycosyl transferase, family 2 GSQ19_05240 ENOG4105C01 Dihydroxy-acid dehydratase GSQ19_05260 ENOG41080HI glycine oxidase GSQ19_05265 ENOG4105VFU Rna-binding protein GSQ19_05285 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) GSQ19_05305 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GSQ19_05320 ENOG4108HMN Caspase domain GSQ19_05345 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein GSQ19_05350 ENOG4105PWN phosphate abc transporter GSQ19_05355 ENOG4105C8U phosphate abc transporter GSQ19_05360 ENOG4105E2Z phosphate ABC transporter (Permease GSQ19_05365 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSQ19_05400 ENOG4105BZU Histidine kinase GSQ19_05405 ENOG4108E1C hydrolase GSQ19_05410 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) GSQ19_05420 ENOG4105M3Z response regulator GSQ19_05430 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer GSQ19_05435 ENOG4105CBS Chea signal transduction histidine kinase GSQ19_05450 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_05455 ENOG4105BZU Histidine kinase GSQ19_05465 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSQ19_05495 ENOG4108XNA Gas vesicle GSQ19_05500 ENOG4105W2E Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity) GSQ19_05515 ENOG4105MRC Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth GSQ19_05520 ENOG4105MRC Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth GSQ19_05540 ENOG4105BZU Histidine kinase GSQ19_05565 ENOG4105D0M Protease HtpX homolog GSQ19_05575 ENOG4105BZF Glycosyl transferase (Group 1 GSQ19_05580 ENOG4105F8J Adenylate Guanylate cyclase GSQ19_05595 ENOG4107QPR SAICAR synthetase GSQ19_05600 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane GSQ19_05605 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GSQ19_05610 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) GSQ19_05615 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GSQ19_05620 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GSQ19_05650 ENOG4105E1J oxidoreductase GSQ19_05655 ENOG4107T8P acyl-Coa dehydrogenase GSQ19_05680 ENOG4105CPC Aldo Keto reductase GSQ19_05685 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 GSQ19_05695 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) GSQ19_05700 ENOG4105E6M Sulphatase-modifying factor protein GSQ19_05705 ENOG4107XGZ Hydrolase GSQ19_05725 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) GSQ19_05730 ENOG4105CHW UPF0052 protein GSQ19_05740 ENOG4105K8N protein family UPF0079, ATPase GSQ19_05750 ENOG4105CD3 dihydroorotase GSQ19_05770 ENOG4105BZU Histidine kinase GSQ19_05775 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_05785 ENOG4105CD2 stage iii sporulation protein aa GSQ19_05795 ENOG4105VFU Rna-binding protein GSQ19_05805 ENOG4105ERG peptidase m48, ste24p GSQ19_05820 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase GSQ19_05825 ENOG4108FN7 Aldo keto reductase GSQ19_05855 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSQ19_05865 ENOG41083EU 50s ribosomal protein l28 GSQ19_05875 ENOG4105IJJ transcriptional regulator, crp fnr family GSQ19_05880 ENOG4105CN1 protease GSQ19_05885 ENOG4108TCG allophycocyanin beta subunit GSQ19_05890 ENOG4105C5F glutamine synthetase GSQ19_05900 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GSQ19_05925 ENOG4105CPQ Dehydrogenase GSQ19_05930 ENOG4105CJ3 phosphate transporter GSQ19_05945 ENOG4108K9Q Controls heterocyst differentiation. Has both a protease and a DNA-binding activity (By similarity) GSQ19_05950 ENOG4105CHM Aminotransferase GSQ19_05955 ENOG4105N6Y Thioredoxin GSQ19_05985 ENOG4108IPT Naphthoate synthase GSQ19_06000 ENOG4105DBI uridine monophosphokinase GSQ19_06015 ENOG4105W5Q DNA repair protein (RadC GSQ19_06035 ENOG4105DCF alanine dehydrogenase GSQ19_06075 ENOG4105DR5 peptidase GSQ19_06085 ENOG4108IDZ Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) GSQ19_06095 ENOG4105K63 Thioredoxin GSQ19_06100 ENOG4105NAN IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) GSQ19_06115 ENOG4105CJ1 ABC, transporter GSQ19_06130 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GSQ19_06140 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) GSQ19_06160 ENOG4105CVN desaturase GSQ19_06195 ENOG4106D5S Corrinoid adenosyltransferase BtuR CobO CobP GSQ19_06200 ENOG410715G filament integrity protein GSQ19_06205 ENOG4105RRH GSQ19_06230 ENOG4108JPW Aminotransferase GSQ19_06250 ENOG4107WDG serine threonine protein kinase GSQ19_06275 ENOG4105BZU Histidine kinase GSQ19_06285 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) GSQ19_06345 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_06360 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate GSQ19_06365 ENOG4108IJ6 ABC transporter GSQ19_06385 ENOG4105C9M aspartyl-trna synthetase GSQ19_06410 ENOG4108RVA ribokinase GSQ19_06435 ENOG4108DIG cyanophycin synthetase GSQ19_06445 ENOG4105F32 YngK protein GSQ19_06460 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) GSQ19_06465 ENOG41060D5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) GSQ19_06485 ENOG4105X0D Fimbrial protein GSQ19_06520 ENOG4106WTF Glycosyl transferase, family 2 GSQ19_06530 ENOG4107Y1F Involved in the transcription termination process (By similarity) GSQ19_06540 ENOG4107SGM protein serine threonine phosphatase GSQ19_06560 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) GSQ19_06575 ENOG4105CKI cobalamin synthesis protein GSQ19_06590 ENOG4105DSE periplasmic solute binding protein GSQ19_06605 ENOG4108RXX maleylacetoacetate isomerase GSQ19_06625 ENOG4105CFG Acts as a chaperone (By similarity) GSQ19_06630 ENOG4105CFP Peptidase U32 GSQ19_06650 ENOG4105CN1 protease GSQ19_06655 ENOG4107R8N Glycosyl transferase, family 2 GSQ19_06670 ENOG4105GHY electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) GSQ19_06725 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) GSQ19_06735 ENOG4105BZU Histidine kinase GSQ19_06740 ENOG410841Q phosphoesterase PA-phosphatase related protein GSQ19_06745 ENOG4105CD8 aminopeptidase N GSQ19_06785 ENOG4107EF8 Glycosyl transferase (Group 1 GSQ19_06790 ENOG4105BZ1 (ABC) transporter GSQ19_06805 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) GSQ19_06810 ENOG4105K9Q Binds to the 23S rRNA (By similarity) GSQ19_06815 ENOG4105CDU Replicative dna helicase GSQ19_06815 ENOG4105CDU Replicative dna helicase GSQ19_06835 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) GSQ19_06850 ENOG4105DDG Cyanophycinase GSQ19_06885 ENOG4105CA3 membrane-bound lytic murein transglycosylase GSQ19_06945 ENOG4105BZU Histidine kinase GSQ19_06950 ENOG4108R99 pseudouridine synthase GSQ19_06955 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) GSQ19_06970 ENOG4105CPF Cell wall formation (By similarity) GSQ19_06985 ENOG4105BZU Histidine kinase GSQ19_07060 ENOG4105CZX twitching motility protein GSQ19_07065 ENOG4107QHF type ii secretion system protein e GSQ19_07070 ENOG4107Z9D Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ GSQ19_07075 ENOG4105CFG Acts as a chaperone (By similarity) GSQ19_07080 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GSQ19_07090 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) GSQ19_07095 ENOG4107RFW hydrolase family 57 GSQ19_07105 ENOG4105D1D Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GSQ19_07110 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GSQ19_07135 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) GSQ19_07175 ENOG4105WGP Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis (By similarity) GSQ19_07225 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I GSQ19_07245 ENOG4108KGH TRANSCRIPTIONal GSQ19_07255 ENOG4105BZU Histidine kinase GSQ19_07285 ENOG4105CJ1 ABC, transporter GSQ19_07295 ENOG41080XM UPF0145 protein GSQ19_07340 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase GSQ19_07345 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase GSQ19_07360 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) GSQ19_07365 ENOG4105D9P serine threonine protein kinase GSQ19_07370 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GSQ19_07380 ENOG4105C3J Cysteine desulfurase GSQ19_07395 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) GSQ19_07400 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GSQ19_07420 ENOG4105WCA Ferredoxin GSQ19_07450 ENOG4105ND9 Nitrogenase-associated protein GSQ19_07495 ENOG4108UR2 Nitrogen fixation protein NifX GSQ19_07510 ENOG4108W3Y Transcriptional regulator, Crp Fnr family GSQ19_07525 ENOG4105C32 Amino acid ABC transporter (Permease) GSQ19_07540 ENOG4105C0Z ABC transporter GSQ19_07555 ENOG4108IV0 ABC, transporter GSQ19_07560 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) GSQ19_07600 ENOG4108TNP GSQ19_07615 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GSQ19_07640 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) GSQ19_07655 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GSQ19_07665 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GSQ19_07670 ENOG4107QRI Phosphoketolase GSQ19_07675 ENOG4108N5B 2-phosphosulfolactate phosphatase GSQ19_07685 ENOG4105D0M Protease HtpX homolog GSQ19_07695 ENOG4108JA5 May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity) GSQ19_07730 ENOG4105C8Q Methyl-accepting chemotaxis GSQ19_07755 ENOG4107UAN Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) GSQ19_07765 ENOG4105CRE cytochrome C GSQ19_07785 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase GSQ19_07795 ENOG4106AG1 Involved in the binding and or turnover of quinones at the Q(B) site of Photosystem II (By similarity) GSQ19_07820 ENOG4105E33 succinate dehydrogenase GSQ19_07835 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) GSQ19_07910 ENOG410801B Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) GSQ19_07935 ENOG4105C7Z Conserved Protein GSQ19_07945 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GSQ19_07975 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) GSQ19_07980 ENOG4105CAS nag kinase GSQ19_07995 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) GSQ19_08030 ENOG4108V3E phosphoribosylglycinamide formyltransferase GSQ19_08070 ENOG4105CFG Acts as a chaperone (By similarity) GSQ19_08075 ENOG4105E5J UV damage endonuclease GSQ19_08100 ENOG4105J0U photosystem II GSQ19_08140 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) GSQ19_08145 ENOG4105W3H MtN3 and saliva related transmembrane protein GSQ19_08155 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase GSQ19_08170 ENOG4105EPU Molybdenum cofactor synthesis domain protein GSQ19_08175 ENOG4105MSA Photosystem II reaction center W protein GSQ19_08195 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) GSQ19_08205 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GSQ19_08220 ENOG4108IND Tetr family transcriptional regulator GSQ19_08245 ENOG4105ZDA GSQ19_08270 ENOG4105BZU Histidine kinase GSQ19_08275 ENOG4105BZU Histidine kinase GSQ19_08285 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_08350 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) GSQ19_08355 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) GSQ19_08365 ENOG4105CI2 imidazolone-5-propionate hydrolase GSQ19_08375 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) GSQ19_08385 ENOG41060KK Stabilizes the structure of photosystem II oxygen- evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity) GSQ19_08390 ENOG4108IYU L-aspartate oxidase GSQ19_08400 ENOG4105BZU Histidine kinase GSQ19_08405 ENOG4105CVB Vitamin K epoxide reductase GSQ19_08415 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) GSQ19_08450 ENOG4105BZU Histidine kinase GSQ19_08455 ENOG4105BZU Histidine kinase GSQ19_08460 ENOG4105BZU Histidine kinase GSQ19_08510 ENOG4105CAK Cell division ATP-binding protein ftsE GSQ19_08520 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_08525 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSQ19_08555 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GSQ19_08570 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) GSQ19_08575 ENOG4106F1P AAA ATPase, central domain protein GSQ19_08590 ENOG4105C7B Threonine dehydratase GSQ19_08605 ENOG4105BZU Histidine kinase GSQ19_08615 ENOG4105CPC Aldo Keto reductase GSQ19_08620 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) GSQ19_08630 ENOG4107NA1 Endonuclease Exonuclease phosphatase GSQ19_08635 ENOG4105D74 hydrolase GSQ19_08660 ENOG4108USA electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) GSQ19_08665 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) GSQ19_08670 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) GSQ19_08675 ENOG4105KZR One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) GSQ19_08680 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity GSQ19_08685 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) GSQ19_08690 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) GSQ19_08695 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) GSQ19_08700 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) GSQ19_08705 ENOG410848H 50s ribosomal protein l29 GSQ19_08710 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal GSQ19_08715 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) GSQ19_08720 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) GSQ19_08725 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits GSQ19_08730 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) GSQ19_08735 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) GSQ19_08740 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) GSQ19_08745 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) GSQ19_08750 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) GSQ19_08755 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) GSQ19_08760 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) GSQ19_08770 ENOG41067V7 50S ribosomal protein L36 GSQ19_08775 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits GSQ19_08780 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) GSQ19_08785 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) GSQ19_08790 ENOG4108ZT0 50S ribosomal protein l17 GSQ19_08795 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) GSQ19_08800 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) GSQ19_08805 ENOG4108UJD 30S ribosomal protein S9 GSQ19_08810 ENOG41082HT Binds the 23S rRNA (By similarity) GSQ19_08815 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) GSQ19_08830 ENOG4105C5H ABC transporter GSQ19_08835 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) GSQ19_08855 ENOG4108KMV Glycosyl transferase (Group 1 GSQ19_08865 ENOG4107XHR Involved in DNA repair and RecF pathway recombination (By similarity) GSQ19_08870 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) GSQ19_08905 ENOG4106CD9 glycosyl transferase group 1 GSQ19_08910 ENOG4105CDA abc transporter atp-binding protein GSQ19_08915 ENOG4105DRP amino acid AbC transporter GSQ19_08920 ENOG4105EZ7 amino acid ABC transporter GSQ19_08925 ENOG4107QXX ABC transporter GSQ19_08945 ENOG4107WPW Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) GSQ19_08950 ENOG4105D3Q Sugar transferase GSQ19_08970 ENOG4105C8S subunit m GSQ19_08975 ENOG4105D65 subunit l GSQ19_08980 ENOG4107XWB Zinc finger, swim domain protein GSQ19_08985 ENOG4105EVY Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) GSQ19_09005 ENOG4105D9R oxidoreductase GSQ19_09010 ENOG410811Q Ferredoxin GSQ19_09015 ENOG4105JFG SpoIID LytB domain protein GSQ19_09095 ENOG4105BZA Phosphoglycerate kinase GSQ19_09110 ENOG4105DKF Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) GSQ19_09135 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP GSQ19_09145 ENOG4107SC0 ferredoxin--NADP reductase GSQ19_09155 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) GSQ19_09190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_09195 ENOG4105BZU Histidine kinase GSQ19_09200 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) GSQ19_09205 ENOG4105C38 Glycyl-tRNA synthetase beta subunit GSQ19_09210 ENOG4105D7N magnesium and cobalt transport protein CorA GSQ19_09225 ENOG4107Z8V Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) GSQ19_09230 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) GSQ19_09235 ENOG4105BZU Histidine kinase GSQ19_09250 ENOG4105FIK Inherit from COG: dihydropteroate synthase GSQ19_09260 ENOG41080UQ Transcriptional regulator GSQ19_09295 ENOG4105C0H protease GSQ19_09305 ENOG4105C0P Mg chelatase subunit ChlI GSQ19_09310 ENOG4107YU2 histidine triad (hIT) protein GSQ19_09320 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) GSQ19_09370 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GSQ19_09375 ENOG4107RSM transcriptional regulator GSQ19_09380 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GSQ19_09385 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GSQ19_09405 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) GSQ19_09430 ENOG4108Z03 MAF-like protein GSQ19_09435 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) GSQ19_09445 ENOG4105PSV Polysaccharide Biosynthesis Protein GSQ19_09450 ENOG4108SHN Glycosyl transferase, family 2 GSQ19_09455 ENOG4108SHN Glycosyl transferase, family 2 GSQ19_09460 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_09475 ENOG4108ZPC Polysaccharide pyruvyl transferase GSQ19_09480 ENOG4105PSV Polysaccharide Biosynthesis Protein GSQ19_09485 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_09495 ENOG4105K64 Glycosyl transferase, family 2 GSQ19_09510 ENOG4105D75 Capsular exopolysaccharide family GSQ19_09515 ENOG4105CG5 Glycosyl transferase (Group 1 GSQ19_09520 ENOG4108KMV Glycosyl transferase (Group 1 GSQ19_09525 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) GSQ19_09530 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) GSQ19_09555 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase GSQ19_09580 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase GSQ19_09585 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_09590 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_09610 ENOG4105BZU Histidine kinase GSQ19_09625 ENOG4105D7T ABC transporter GSQ19_09650 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) GSQ19_09660 ENOG4105CH5 extracellular solute-binding protein, family 7 GSQ19_09665 ENOG4105CG6 trap dicarboxylate transporter dctm subunit GSQ19_09695 ENOG4105D64 Mechanosensitive ion channel GSQ19_09705 ENOG4108UN4 phage SPO1 DNA polymerase-related protein GSQ19_09715 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) GSQ19_09795 ENOG4105KEG ribosomal-protein-alanine acetyltransferase GSQ19_09805 ENOG4105C8B TIGR00159 family GSQ19_09810 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) GSQ19_09835 ENOG4108KBA Acts as a chaperone (By similarity) GSQ19_09840 ENOG4107VAM peptidase, m28 GSQ19_09850 ENOG4105FFC UPF0187 protein GSQ19_09860 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) GSQ19_09865 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) GSQ19_09870 ENOG4108JQC penicillin-binding protein 1A GSQ19_09905 ENOG4105CHC glucokinase (EC 2.7.1.2) GSQ19_09930 ENOG4107S73 homocitrate synthase GSQ19_09940 ENOG4105CVP deoxyribo-dipyrimidine photolyase GSQ19_09950 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSQ19_09990 ENOG4108JQC penicillin-binding protein 1A GSQ19_09995 ENOG4105CB5 ATP-dependent DNA helicase recG GSQ19_10025 ENOG4108DJF Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) GSQ19_10030 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) GSQ19_10045 ENOG4105DB7 PHP domain protein GSQ19_10055 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) GSQ19_10060 ENOG4105CAT Cytidine monophosphate kinase GSQ19_10065 ENOG4105K6T rare lipoprotein A GSQ19_10070 ENOG4105CSV Glutaminase GSQ19_10075 ENOG4105CA3 membrane-bound lytic murein transglycosylase GSQ19_10105 ENOG4108UHE carbonic anhydrase GSQ19_10110 ENOG4105VFU Rna-binding protein GSQ19_10120 ENOG41081UC Inherit from COG: Competence protein GSQ19_10140 ENOG4105DTD Dehydrogenase GSQ19_10165 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GSQ19_10170 ENOG410811H Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) GSQ19_10175 ENOG4108M11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_10185 ENOG4108IV0 ABC, transporter GSQ19_10190 ENOG4107R0W ABC transporter GSQ19_10195 ENOG4108V9Q carbonic anhydrase GSQ19_10205 ENOG4105C59 p-type ATPase GSQ19_10260 ENOG4105PGM cation diffusion facilitator family transporter GSQ19_10265 ENOG4105BZU Histidine kinase GSQ19_10275 ENOG4105BZU Histidine kinase GSQ19_10285 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) GSQ19_10290 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) GSQ19_10310 ENOG4108W6C Dehydrogenase GSQ19_10340 ENOG4105EHU Circadian clock protein KaiC GSQ19_10345 ENOG4108ZGN Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity) GSQ19_10350 ENOG4108WXF Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC hexamer phosphorylation GSQ19_10355 ENOG4105BZU Histidine kinase GSQ19_10390 ENOG4105CNG UPF0061 protein GSQ19_10395 ENOG4105BZU Histidine kinase GSQ19_10420 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) GSQ19_10455 ENOG4105CPK Glycosyl transferase (Group 1 GSQ19_10475 ENOG4107YJ4 chain length determinant protein GSQ19_10490 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GSQ19_10515 ENOG4107VQD May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) GSQ19_10520 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) GSQ19_10570 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) GSQ19_10575 ENOG4105KVH Transcriptional regulator GSQ19_10595 ENOG4107VEG TrkA-N domain protein GSQ19_10635 ENOG4105CE1 Ferrous iron transport protein b GSQ19_10660 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GSQ19_10700 ENOG4105C4W S-formylglutathione hydrolase GSQ19_10710 ENOG4107QPD alcohol dehydrogenase GSQ19_10715 ENOG4105JKW Valine--pyruvate aminotransferase GSQ19_10720 ENOG41080P6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) GSQ19_10770 ENOG4108UNF response regulator GSQ19_10775 ENOG4108M24 von Willebrand factor, type A GSQ19_10790 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase GSQ19_10795 ENOG4105D5U fad dependent oxidoreductase GSQ19_10800 ENOG4105CMR udp-glucose 4-epimerase GSQ19_10825 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GSQ19_10835 ENOG4108TJN glycosyl transferase group 1 GSQ19_10840 ENOG4107YJ4 chain length determinant protein GSQ19_10845 ENOG4105D3Q Sugar transferase GSQ19_10850 ENOG4105BZ1 (ABC) transporter GSQ19_10855 ENOG4108SHN Glycosyl transferase, family 2 GSQ19_10870 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_10950 ENOG4105FTV AraC Family Transcriptional Regulator GSQ19_10955 ENOG4107T8Q Glycosyl transferase (Group 1 GSQ19_10975 ENOG4105D5K Hemolysin activator protein GSQ19_10995 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) GSQ19_11005 ENOG4105BZU Histidine kinase GSQ19_11025 ENOG4105D9P serine threonine protein kinase GSQ19_11040 ENOG4105DZR Type I site-specific deoxyribonuclease GSQ19_11045 ENOG4105CB5 ATP-dependent DNA helicase recG GSQ19_11050 ENOG4107XZC Restriction modification system DNA (Specificity GSQ19_11075 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) GSQ19_11080 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase GSQ19_11085 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_11090 ENOG4107XWZ ferric uptake regulator GSQ19_11100 ENOG4105CTK cobaltochelatase, cobn subunit GSQ19_11105 ENOG4105BZU Histidine kinase GSQ19_11125 ENOG4105CJW magnesium transporter GSQ19_11135 ENOG4105CXT aspartate transcarbamylase GSQ19_11140 ENOG4105C08 Histidine kinase GSQ19_11150 ENOG4107QN1 sodium solute GSQ19_11160 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) GSQ19_11170 ENOG4108MV2 Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity) GSQ19_11190 ENOG4106CD9 glycosyl transferase group 1 GSQ19_11200 ENOG4108JJA ABC, transporter GSQ19_11205 ENOG4105C42 Type I secretion membrane fusion protein (HlyD GSQ19_11220 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) GSQ19_11230 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_11235 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_11240 ENOG4105QPS Monooxygenase GSQ19_11250 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_11260 ENOG4105NP4 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity) GSQ19_11280 ENOG4105D82 Glutamate dehydrogenase GSQ19_11290 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) GSQ19_11325 ENOG4108302 MgtC SapB transporter GSQ19_11370 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) GSQ19_11385 ENOG4105VUN Transcriptional regulator GSQ19_11400 ENOG4105CDY transcriptional regulatory protein GSQ19_11450 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) GSQ19_11455 ENOG41068WN GSQ19_11465 ENOG4108S5W Seems to be required for the assembly of the photosystem I complex (By similarity) GSQ19_11470 ENOG4105D6H One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity) GSQ19_11490 ENOG4108E1C hydrolase GSQ19_11500 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSQ19_11535 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_11570 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) GSQ19_11575 ENOG4105EEX Two component transcriptional regulator (Winged helix family GSQ19_11590 ENOG4105CPU Monooxygenase GSQ19_11595 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) GSQ19_11610 ENOG4105WN2 Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity) GSQ19_11615 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) GSQ19_11620 ENOG4105X1F electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity) GSQ19_11625 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) GSQ19_11635 ENOG4105J3Z Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) GSQ19_11645 ENOG4105CHM Aminotransferase GSQ19_11660 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) GSQ19_11670 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) GSQ19_11675 ENOG4108XAD Protein of unknown function (DUF1997) GSQ19_11685 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) GSQ19_11690 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) GSQ19_11695 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) GSQ19_11700 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) GSQ19_11705 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) GSQ19_11710 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) GSQ19_11720 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GSQ19_11735 ENOG4108ZJ4 polysaccharide deacetylase GSQ19_11745 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) GSQ19_11760 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) GSQ19_11785 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GSQ19_11790 ENOG41084IE Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GSQ19_11805 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase GSQ19_11820 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ GSQ19_11840 ENOG4105CFG Acts as a chaperone (By similarity) GSQ19_11860 ENOG41084GG 50S ribosomal protein L33 GSQ19_11865 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) GSQ19_11880 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) GSQ19_11910 ENOG4105VMP Transcriptional regulator GSQ19_11990 ENOG410890F Dynamin family GSQ19_11995 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GSQ19_12020 ENOG4105CNF WD-40 repeat protein GSQ19_12030 ENOG4105D3R alkyl hydroperoxide reductase GSQ19_12050 ENOG4107STW synthase GSQ19_12060 ENOG4105CPK Glycosyl transferase (Group 1 GSQ19_12065 ENOG4107RGC Glycosyl transferase, family 2 GSQ19_12080 ENOG4105CNW domain protein GSQ19_12090 ENOG4105CNW domain protein GSQ19_12105 ENOG4105D3Q Sugar transferase GSQ19_12110 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family GSQ19_12130 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_12160 ENOG4105K64 Glycosyl transferase, family 2 GSQ19_12225 ENOG4107S78 Band 7 protein GSQ19_12240 ENOG4105EYM Major Facilitator superfamily GSQ19_12260 ENOG4105CJT Mannose-1-phosphate guanylyltransferase GSQ19_12285 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_12290 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_12320 ENOG4108R6K riboflavin synthase, subunit alpha GSQ19_12325 ENOG41063SB peptidase GSQ19_12330 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase GSQ19_12340 ENOG4105C09 Bile acid GSQ19_12345 ENOG4106MP8 UPF0754 membrane protein GSQ19_12350 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) GSQ19_12355 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSQ19_12365 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation GSQ19_12415 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GSQ19_12420 ENOG4105D0M Protease HtpX homolog GSQ19_12425 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) GSQ19_12445 ENOG4105CNW domain protein GSQ19_12450 ENOG4105CNW domain protein GSQ19_12490 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_12515 ENOG4105CJ1 ABC, transporter GSQ19_12560 ENOG4105DFF Rod shape-determining protein mreb GSQ19_12565 ENOG41080E3 single-stranded DNA-binding protein GSQ19_12580 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GSQ19_12585 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase GSQ19_12590 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) GSQ19_12635 ENOG4105KC4 UPF0296 protein GSQ19_12645 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) GSQ19_12650 ENOG4108W6I photosystem I reaction center protein subunit XI GSQ19_12655 ENOG4106AST May help in the organization of the PsaE and PsaF subunits (By similarity) GSQ19_12660 ENOG4108VV8 photosystem i GSQ19_12665 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) GSQ19_12700 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) GSQ19_12705 ENOG4105BZU Histidine kinase GSQ19_12720 ENOG4108JIS Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) GSQ19_12750 ENOG4108IJ6 ABC transporter GSQ19_12765 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_12800 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GSQ19_12810 ENOG4105YVZ photosystem II GSQ19_12825 ENOG4105DEF Extracellular solute-binding protein, family 5 GSQ19_12830 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component GSQ19_12835 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) GSQ19_12855 ENOG4105K46 50S ribosomal protein l27 GSQ19_12860 ENOG41082FX This protein binds to 23S rRNA in the presence of protein L20 (By similarity) GSQ19_12875 ENOG4105EET magnesium chelatase GSQ19_12880 ENOG4105FQP Beta-lactamase GSQ19_12910 ENOG4107T8Q Glycosyl transferase (Group 1 GSQ19_12915 ENOG4105CPK Glycosyl transferase (Group 1 GSQ19_12925 ENOG4105TQG cytochrome C, class I GSQ19_12940 ENOG41086DT Membrane protein of unknown function GSQ19_12950 ENOG4105BZM domain protein GSQ19_12960 ENOG4107SKI cobyrinic Acid a,c-diamide synthase GSQ19_13000 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) GSQ19_13025 ENOG4105C59 p-type ATPase GSQ19_13065 ENOG4108HMN Caspase domain GSQ19_13075 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_13085 ENOG4105BZU Histidine kinase GSQ19_13090 ENOG4105BZU Histidine kinase GSQ19_13095 ENOG4105BZU Histidine kinase GSQ19_13110 ENOG4105BZU Histidine kinase GSQ19_13120 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_13125 ENOG41082AN stage II sporulation protein GSQ19_13130 ENOG4107QJZ Glycosyl transferase, family 2 GSQ19_13150 ENOG4108W6C Dehydrogenase GSQ19_13160 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_13175 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) GSQ19_13195 ENOG4105EWK phytoene GSQ19_13205 ENOG41088WE This is one of the two reaction center proteins of photosystem II GSQ19_13210 ENOG4105EA8 2-Nitropropane dioxygenase GSQ19_13220 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control GSQ19_13240 ENOG4105EIE fructose-bisphosphate aldolase GSQ19_13250 ENOG4107WDG serine threonine protein kinase GSQ19_13255 ENOG4107S1Q Phosphatase GSQ19_13260 ENOG4105DXX methyltransferase GSQ19_13270 ENOG4108IG5 Transcriptional regulator GSQ19_13275 ENOG4105EY5 This is one of the two reaction center proteins of photosystem II GSQ19_13280 ENOG4105DF7 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity) GSQ19_13285 ENOG4105CC5 ABC transporter GSQ19_13290 ENOG4105DIK (ABC) transporter GSQ19_13295 ENOG4105DSE periplasmic solute binding protein GSQ19_13335 ENOG4105C0W non-ribosomal peptide synthetase GSQ19_13425 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_13430 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_13435 ENOG4105BZU Histidine kinase GSQ19_13455 ENOG4105D8X mechanosensitive ion channel GSQ19_13490 ENOG4108IUZ ABC transporter GSQ19_13515 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase GSQ19_13530 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein GSQ19_13535 ENOG4107SQU synthase GSQ19_13545 ENOG4107RCI amp-dependent synthetase and ligase GSQ19_13555 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) GSQ19_13565 ENOG4107RHB Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity) GSQ19_13575 ENOG4108HHA Transketolase GSQ19_13595 ENOG4105CHF Glutathione S-transferase GSQ19_13605 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) GSQ19_13635 ENOG4105D7W serine acetyltransferase GSQ19_13640 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) GSQ19_13650 ENOG4105X25 GSQ19_13655 ENOG4107ZSV Receptor GSQ19_13665 ENOG4105C4M (Ubiquinol oxidase) subunit I GSQ19_13695 ENOG4105VFU Rna-binding protein GSQ19_13700 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 GSQ19_13705 ENOG4107QQX Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) GSQ19_13710 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase GSQ19_13715 ENOG4107RNI Glucose 6-phosphate dehydrogenase effector OpcA GSQ19_13755 ENOG4108VHC Short-chain dehydrogenase reductase Sdr GSQ19_13800 ENOG4107WDG serine threonine protein kinase GSQ19_13825 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) GSQ19_13860 ENOG4105EYH Exonuclease GSQ19_13865 ENOG4105BZU Histidine kinase GSQ19_13875 ENOG4108SHJ s-layer protein GSQ19_13880 ENOG4105BZU Histidine kinase GSQ19_13905 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) GSQ19_13935 ENOG4105DZP Membrane-associated zinc metalloprotease GSQ19_13945 ENOG41082AF Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) GSQ19_13955 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) GSQ19_13970 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GSQ19_14005 ENOG4105C8S subunit m GSQ19_14015 ENOG4105K63 Thioredoxin GSQ19_14025 ENOG4105DUM transcriptional regulator, lysR family GSQ19_14035 ENOG4105C75 arginyL-tRNA synthetase GSQ19_14040 ENOG410667J hydrolase GSQ19_14045 ENOG4108JJB ABC transporter GSQ19_14055 ENOG4105G01 cobalamin (vitamin B12) biosynthesis CbiM protein GSQ19_14060 ENOG4108JJB ABC transporter GSQ19_14065 ENOG4108V4M Cobalt abc transporter GSQ19_14070 ENOG4105W4R Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) GSQ19_14075 ENOG4105CFT Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity) GSQ19_14080 ENOG4105E3B Multicopper oxidase GSQ19_14100 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GSQ19_14110 ENOG4107QZB decarboxylase GSQ19_14115 ENOG4105K70 DNA-binding protein GSQ19_14120 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) GSQ19_14125 ENOG4105F32 YngK protein GSQ19_14155 ENOG4105D44 asparaginase GSQ19_14160 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) GSQ19_14165 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_14170 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) GSQ19_14175 ENOG4105KHC sulfurtransferase GSQ19_14195 ENOG4105CMV Succinyl-CoA synthetase subunit beta GSQ19_14200 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha GSQ19_14205 ENOG4108Q6X Aspartoacylase (EC 3.5.1.15) GSQ19_14210 ENOG4105CUG Oligopeptidase b GSQ19_14220 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) GSQ19_14225 ENOG4107P5I polyketide synthase GSQ19_14245 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) GSQ19_14260 ENOG4105E0X reductase GSQ19_14280 ENOG4105CAN Short-chain dehydrogenase reductase Sdr GSQ19_14285 ENOG4107ZH9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) GSQ19_14290 ENOG4105CNW domain protein GSQ19_14300 ENOG4105CNW domain protein GSQ19_14310 ENOG4105CH7 arginosuccinase GSQ19_14320 ENOG4105DTC 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase GSQ19_14325 ENOG4107QRA Extracellular solute-binding protein, family 5 GSQ19_14330 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) GSQ19_14335 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) GSQ19_14340 ENOG4105DDG Cyanophycinase GSQ19_14345 ENOG4107RRY Cyanophycin synthetase GSQ19_14350 ENOG41063NY Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) GSQ19_14355 ENOG4107WDG serine threonine protein kinase GSQ19_14360 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase GSQ19_14405 ENOG4105C9B Cysteine desulfurase GSQ19_14420 ENOG4105D7V transposase GSQ19_14425 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) GSQ19_14445 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) GSQ19_14455 ENOG4105D7Z glutathione synthase GSQ19_14460 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) GSQ19_14480 ENOG4108HMN Caspase domain GSQ19_14490 ENOG4105CPJ photosystem II manganese-stabilizing GSQ19_14540 ENOG4106DN3 This protein is a component of the reaction center of photosystem II (By similarity) GSQ19_14550 ENOG410689D This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity) GSQ19_14555 ENOG4105NT3 This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity) GSQ19_14560 ENOG4107SP2 The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity GSQ19_14565 ENOG410828V rubredoxin GSQ19_14570 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain GSQ19_14575 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_14580 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain GSQ19_14595 ENOG4107EXU Short-chain dehydrogenase reductase Sdr GSQ19_14615 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) GSQ19_14625 ENOG4105CHV Transcription elongation factor NusA GSQ19_14630 ENOG4107ZR3 Required for maturation of 30S ribosomal subunits (By similarity) GSQ19_14725 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GSQ19_14730 ENOG4105M6F mutator MutT protein GSQ19_14740 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_14745 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain GSQ19_14750 ENOG4108NWW ferritin dps family protein GSQ19_14760 ENOG4105E0R Deoxyhypusine synthase GSQ19_14770 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase GSQ19_14785 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GSQ19_14790 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSQ19_14800 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GSQ19_14810 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_14840 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) GSQ19_14855 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) GSQ19_14870 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_14875 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) GSQ19_14890 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) GSQ19_14895 ENOG4105ETX regulatoR GSQ19_14915 ENOG4105DK0 Indole-3-glycerol phosphate synthase GSQ19_14990 ENOG4105CTK cobaltochelatase, cobn subunit GSQ19_14995 ENOG4105BZ1 (ABC) transporter GSQ19_15000 ENOG4105BZ1 (ABC) transporter GSQ19_15010 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_15015 ENOG4105BZU Histidine kinase GSQ19_15020 ENOG4105D52 delta-aminolevulinic acid dehydratase GSQ19_15025 ENOG4105C22 threonyL-tRNA synthetase GSQ19_15030 ENOG4105CKI cobalamin synthesis protein GSQ19_15035 ENOG4105EUJ GTP cyclohydrolase i GSQ19_15045 ENOG4105D3Q Sugar transferase GSQ19_15050 ENOG4105C1J atp-dependent rna helicase GSQ19_15065 ENOG4105BZ1 (ABC) transporter GSQ19_15075 ENOG4105CMR udp-glucose 4-epimerase GSQ19_15085 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) GSQ19_15090 ENOG4107VAM peptidase, m28 GSQ19_15100 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) GSQ19_15110 ENOG4107QRG dna polymerase iii GSQ19_15125 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) GSQ19_15130 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) GSQ19_15135 ENOG4105CIA precorrin-4 C(11)-methyltransferase GSQ19_15145 ENOG4108YZN class I peptide chain release factor GSQ19_15155 ENOG41080ZE Adenylate cyclase GSQ19_15170 ENOG4105K56 Transcriptional regulator GSQ19_15180 ENOG4108KQJ Type 11 methyltransferase GSQ19_15200 ENOG4105JZI cytochrome P450 GSQ19_15205 ENOG4108X7A Terpene synthase metal-binding domain-containing protein GSQ19_15220 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase GSQ19_15240 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) GSQ19_15255 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) GSQ19_15270 ENOG4105C5T Phosphoribosyl pyrophosphate synthase GSQ19_15275 ENOG4107WDG serine threonine protein kinase GSQ19_15280 ENOG4107Y82 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) GSQ19_15305 ENOG4108VPT UPF0234 protein GSQ19_15310 ENOG4105CYM Glutathione S-transferase GSQ19_15335 ENOG4107S5T Carbohydrate kinase GSQ19_15340 ENOG4105RD7 BadF BadG BcrA BcrD GSQ19_15355 ENOG41063FQ CsbD-like protein GSQ19_15385 ENOG4105WXN Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) GSQ19_15400 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin GSQ19_15410 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) GSQ19_15450 ENOG4105BZU Histidine kinase GSQ19_15455 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_15460 ENOG4108Z6B deaminase GSQ19_15465 ENOG4105EYW Ion transport protein GSQ19_15475 ENOG4105EWK phytoene GSQ19_15505 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) GSQ19_15540 ENOG4108JQ6 ABC transporter GSQ19_15565 ENOG4108IJ9 (ABC) transporter GSQ19_15580 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis GSQ19_15585 ENOG41085RW This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) GSQ19_15590 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GSQ19_15615 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) GSQ19_15620 ENOG4105CE9 30S ribosomal protein S2 GSQ19_15635 ENOG4107R51 Glycosyl transferase, family 2 GSQ19_15655 ENOG4105CDH Citrulline--aspartate ligase GSQ19_15665 ENOG41082AN stage II sporulation protein GSQ19_15675 ENOG41082BG Binds together with S18 to 16S ribosomal RNA (By similarity) GSQ19_15680 ENOG4105ERH Fumarylacetoacetate hydrolase GSQ19_15695 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) GSQ19_15700 ENOG4105ESV Glycosyl transferase, family 4 GSQ19_15705 ENOG4105CEV competence damage-inducible protein GSQ19_15725 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) GSQ19_15735 ENOG4107WDG serine threonine protein kinase GSQ19_15755 ENOG4105KRQ Addiction module toxin, Txe YoeB family GSQ19_15765 ENOG4107R4J Chloride channel GSQ19_15785 ENOG4105D3Q Sugar transferase GSQ19_15790 ENOG4105DRS transport system, permease GSQ19_15795 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase GSQ19_15805 ENOG4105C0K Gdp-mannose 4,6-dehydratase GSQ19_15810 ENOG4105D3Q Sugar transferase GSQ19_15815 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_15820 ENOG4105CMR udp-glucose 4-epimerase GSQ19_15830 ENOG4105JZI cytochrome P450 GSQ19_15835 ENOG4108HMN Caspase domain GSQ19_15870 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) GSQ19_15875 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) GSQ19_15885 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) GSQ19_15890 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) GSQ19_15895 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) GSQ19_15900 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) GSQ19_15910 ENOG4105C7R Atpase associated with various cellular activities aaa_3 GSQ19_15930 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving GSQ19_15935 ENOG4108JA2 transcriptioN-repair coupling factor GSQ19_15960 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase GSQ19_15965 ENOG4107TVC Glycosyl transferase, family 2 GSQ19_15980 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) GSQ19_15995 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein GSQ19_16000 ENOG4105EY5 This is one of the two reaction center proteins of photosystem II GSQ19_16010 ENOG4107VE4 peptidase S8 and S53, subtilisin, kexin, sedolisin GSQ19_16020 ENOG4108Z6B deaminase GSQ19_16050 ENOG4105BZU Histidine kinase GSQ19_16055 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_16060 ENOG4105BZU Histidine kinase GSQ19_16070 ENOG4105BZU Histidine kinase GSQ19_16075 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_16095 ENOG4105CXN decarboxylase GSQ19_16110 ENOG4105CMQ Chloride channel GSQ19_16145 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) GSQ19_16150 ENOG4105ETE Transcriptional regulator (LacI family GSQ19_16155 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator GSQ19_16160 ENOG4105C2J ABC transporter GSQ19_16165 ENOG4105CNN ABC, transporter GSQ19_16180 ENOG4105BZU Histidine kinase GSQ19_16185 ENOG4105CVJ phosphoglycerate mutase GSQ19_16215 ENOG4105CNF WD-40 repeat protein GSQ19_16220 ENOG4108HMN Caspase domain GSQ19_16245 ENOG4105C0D helicase GSQ19_16290 ENOG4105DBV ornithine carbamoyltransferase GSQ19_16345 ENOG4105EYH Exonuclease GSQ19_16370 ENOG4105C6E dna polymerase iii GSQ19_16375 ENOG4105KK4 UPF0060 membrane protein GSQ19_16380 ENOG4105CND Glycosyl transferase, family 2 GSQ19_16400 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) GSQ19_16425 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) GSQ19_16435 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 GSQ19_16510 ENOG4105CIH Imidazole acetol-phosphate transaminase GSQ19_16515 ENOG4105IPS esterase GSQ19_16520 ENOG4105DC8 reductase GSQ19_16540 ENOG4105U3E Transcriptional regulator GSQ19_16555 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GSQ19_16560 ENOG4105DGI Alkaline phosphatase GSQ19_16585 ENOG4108KQI regulatory protein luxr GSQ19_16610 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase GSQ19_16615 ENOG4105CUT histidyl-tRNA synthetase GSQ19_16630 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSQ19_16640 ENOG4105DKQ ROK family GSQ19_16650 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) GSQ19_16655 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase GSQ19_16680 ENOG4105CIK Amidinotransferase GSQ19_16705 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) GSQ19_16725 ENOG4105DUM transcriptional regulator, lysR family GSQ19_16730 ENOG4107STW synthase GSQ19_16750 ENOG4105PYN Pyridoxamine 5-phosphate oxidase-related GSQ19_16760 ENOG4108UV1 cellular component movement GSQ19_16780 ENOG4105C7R Atpase associated with various cellular activities aaa_3 GSQ19_16800 ENOG410823V Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) GSQ19_16805 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) GSQ19_16820 ENOG4105F38 ABC transporter, permease GSQ19_16825 ENOG4107RUE extracellular solute-binding protein family 1 GSQ19_16830 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) GSQ19_16840 ENOG4105CJN penicillin-binding protein GSQ19_16860 ENOG4105C8S subunit m GSQ19_16875 ENOG4107QP0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) GSQ19_16885 ENOG4107YCR Transcriptional regulator, ARSR family GSQ19_16890 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein GSQ19_16895 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) GSQ19_16905 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) GSQ19_16910 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GSQ19_16915 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) GSQ19_16925 ENOG4105DFU Cell wall formation (By similarity) GSQ19_16930 ENOG4105D4A Cell wall formation (By similarity) GSQ19_16935 ENOG41082EZ Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) GSQ19_16945 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_16950 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) GSQ19_16975 ENOG4105BZU Histidine kinase GSQ19_16985 ENOG4105C78 Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) GSQ19_16995 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) GSQ19_17010 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSQ19_17045 ENOG4105EWK phytoene GSQ19_17075 ENOG4105CPQ Dehydrogenase GSQ19_17080 ENOG4105D5K Hemolysin activator protein GSQ19_17100 ENOG4105IB0 filamentous hemagglutinin family outer membrane protein GSQ19_17110 ENOG4107QSS Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity) GSQ19_17120 ENOG4108JQB penicillin-binding protein 1C GSQ19_17125 ENOG4105DN3 alpha-2-macroglobulin domain protein GSQ19_17130 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) GSQ19_17150 ENOG4105C37 (CBS) domain GSQ19_17155 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) GSQ19_17165 ENOG4107T5V SNARE associated Golgi GSQ19_17180 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GSQ19_17185 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) GSQ19_17205 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) GSQ19_17255 ENOG4105CVM Molybdenum cofactor synthesis domain protein GSQ19_17265 ENOG4107RIQ Sulfate adenylate transferase GSQ19_17295 ENOG4105K64 Glycosyl transferase, family 2 GSQ19_17310 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GSQ19_17345 ENOG4108JJA ABC, transporter GSQ19_17360 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family GSQ19_17370 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) GSQ19_17380 ENOG4105MN0 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 GSQ19_17385 ENOG4105F37 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 GSQ19_17430 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) GSQ19_17455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_17460 ENOG4105BZU Histidine kinase GSQ19_17475 ENOG4105F4R Transcriptional regulator mode GSQ19_17480 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein GSQ19_17500 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GSQ19_17510 ENOG4105CJW magnesium transporter GSQ19_17525 ENOG4107T8Q Glycosyl transferase (Group 1 GSQ19_17530 ENOG4105E2K Glycosyl transferase (Group 1 GSQ19_17535 ENOG4105BZ1 (ABC) transporter GSQ19_17545 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_17555 ENOG4105GR3 Histidine kinase GSQ19_17560 ENOG4105ETX regulatoR GSQ19_17570 ENOG4105CAU Arsenical resistance protein, ArsH GSQ19_17575 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSQ19_17580 ENOG4105VGQ Photosystem I subunit X GSQ19_17595 ENOG4108UHU Aldolase GSQ19_17660 ENOG4105EY5 This is one of the two reaction center proteins of photosystem II GSQ19_17665 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) GSQ19_17695 ENOG4107S17 Phosphate-binding protein GSQ19_17710 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) GSQ19_17725 ENOG4108JQC penicillin-binding protein 1A GSQ19_17735 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) GSQ19_17750 ENOG4105C8U phosphate abc transporter GSQ19_17755 ENOG4105E2Z phosphate ABC transporter (Permease GSQ19_17760 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) GSQ19_17770 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) GSQ19_17775 ENOG4108RXX maleylacetoacetate isomerase GSQ19_17785 ENOG4108V5Q transglutaminase-like protein GSQ19_17800 ENOG4108I6A alcohol dehydrogenase GSQ19_17815 ENOG4105D2N Aldolase GSQ19_17865 ENOG4105CBX hi0933 family GSQ19_17890 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GSQ19_17905 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_17910 ENOG4105KZX Pterin carbinolamine dehydratase GSQ19_17915 ENOG4105D6H One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity) GSQ19_17920 ENOG4105VUV UPF0367 protein GSQ19_17925 ENOG4108JJB ABC transporter GSQ19_17930 ENOG4105M0M Tetracycline resistance protein GSQ19_17955 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) GSQ19_17960 ENOG4107WDG serine threonine protein kinase GSQ19_17965 ENOG4105CQB FAD linked oxidase domain protein GSQ19_17975 ENOG4105F32 YngK protein GSQ19_18005 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) GSQ19_18030 ENOG4105DRS transport system, permease GSQ19_18035 ENOG410612X Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane GSQ19_18045 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) GSQ19_18055 ENOG4105EUJ GTP cyclohydrolase i GSQ19_18060 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase GSQ19_18065 ENOG4105VGQ Photosystem I subunit X GSQ19_18070 ENOG4106INZ Photosystem I reaction center subunit GSQ19_18080 ENOG4108Y85 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) GSQ19_18095 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GSQ19_18110 ENOG4108SGK Tetr family transcriptional regulator GSQ19_18115 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) GSQ19_18135 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) GSQ19_18140 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) GSQ19_18145 ENOG4107Z3D 50S ribosomal protein l10 GSQ19_18150 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) GSQ19_18175 ENOG4107SBE Glycosyl transferase (Group 1 GSQ19_18185 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_18190 ENOG4105BZU Histidine kinase GSQ19_18210 ENOG4106JD1 PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6 (By similarity) GSQ19_18300 ENOG4105K70 DNA-binding protein GSQ19_18335 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_18355 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_18580 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) GSQ19_18585 ENOG4108SMZ Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity) GSQ19_18630 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity) GSQ19_18645 ENOG4108JA1 polyketide synthase GSQ19_18650 ENOG4105C0W non-ribosomal peptide synthetase GSQ19_18660 ENOG4107SQU synthase GSQ19_18665 ENOG4107QKG PfaD family GSQ19_18670 ENOG4107P5I polyketide synthase GSQ19_18680 ENOG4108W6C Dehydrogenase GSQ19_18695 ENOG4108JQ9 ABC transporter GSQ19_18725 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GSQ19_18755 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) GSQ19_18760 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) GSQ19_18765 ENOG4105E3N F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GSQ19_18770 ENOG4105VYJ F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GSQ19_18775 ENOG4105S30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GSQ19_18780 ENOG4105VH4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) GSQ19_18785 ENOG4107SM1 it plays a direct role in the translocation of protons across the membrane (By similarity) GSQ19_18790 ENOG4105PA3 atp synthase GSQ19_18795 ENOG4107SWE Methyltransferase GSQ19_18805 ENOG4105EEK Polypeptide GSQ19_18810 ENOG4108MAQ allophycocyanin alpha GSQ19_18815 ENOG4105FBM allophycocyanin beta subunit GSQ19_18820 ENOG4105W5K Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity) GSQ19_18825 ENOG41063JG Transcriptional regulator GSQ19_18850 ENOG4105CNF WD-40 repeat protein GSQ19_18860 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) GSQ19_18865 ENOG4105E4F Isochorismate synthase GSQ19_18935 ENOG4108ISE 4Fe-4S ferredoxin, iron-sulfur binding GSQ19_18965 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) GSQ19_18970 ENOG4105K63 Thioredoxin GSQ19_18995 ENOG4105C5I Dehydrogenase GSQ19_19000 ENOG4107YJ4 chain length determinant protein GSQ19_19020 ENOG41082QS Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) GSQ19_19035 ENOG4105DHP deoxycytidine triphosphate deaminase GSQ19_19045 ENOG4106QP8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) GSQ19_19050 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) GSQ19_19060 ENOG4105DHJ ABC, transporter GSQ19_19070 ENOG4105BZU Histidine kinase GSQ19_19085 ENOG4105N7N Pentapeptide repeat-containing protein GSQ19_19090 ENOG4108KGH TRANSCRIPTIONal GSQ19_19105 ENOG4105CJ1 ABC, transporter GSQ19_19115 ENOG4105D9P serine threonine protein kinase GSQ19_19155 ENOG4105C8M UPF0272 protein GSQ19_19160 ENOG4107RTD sua5 ycio yrdc ywlc family protein GSQ19_19175 ENOG4105C9U ATP-dependent DNA helicase RecQ GSQ19_19200 ENOG4108RJ7 Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity) GSQ19_19210 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) GSQ19_19240 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) GSQ19_19265 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) GSQ19_19270 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_19275 ENOG4107YX3 NADH dehydrogenase subunit j GSQ19_19280 ENOG41082X4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_19285 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) GSQ19_19310 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) GSQ19_19330 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) GSQ19_19335 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) GSQ19_19340 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) GSQ19_19350 ENOG4105CEY Amp-dependent synthetase and ligase GSQ19_19380 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) GSQ19_19425 ENOG4105H0N Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I GSQ19_19430 ENOG4108UQX Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity) GSQ19_19435 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component GSQ19_19450 ENOG4108UXN response regulator GSQ19_19465 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_19490 ENOG4105N7N Pentapeptide repeat-containing protein GSQ19_19495 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) GSQ19_19500 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) GSQ19_19505 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor GSQ19_19515 ENOG4105CMS peptidase U62, modulator of DNA gyrase GSQ19_19550 ENOG4105BZU Histidine kinase GSQ19_19580 ENOG4107RAQ aminopeptidase GSQ19_19595 ENOG4105DDQ anthranilate synthase GSQ19_19605 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) GSQ19_19630 ENOG4105C22 threonyL-tRNA synthetase GSQ19_19635 ENOG4105CNF WD-40 repeat protein GSQ19_19645 ENOG4105CK2 sodium dicarboxylate symporter GSQ19_19650 ENOG4105D9P serine threonine protein kinase GSQ19_19665 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) GSQ19_19675 ENOG4105C8S subunit m GSQ19_19685 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GSQ19_19700 ENOG4105DTD Dehydrogenase GSQ19_19715 ENOG4105D9P serine threonine protein kinase GSQ19_19720 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs GSQ19_19770 ENOG410834F Transcriptional regulator GSQ19_19800 ENOG4105CNF WD-40 repeat protein GSQ19_19810 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) GSQ19_19815 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) GSQ19_19820 ENOG4108E2B had-superfamily hydrolase, subfamily iib GSQ19_19830 ENOG4105D9N nucleoside GSQ19_19835 ENOG4107Z12 Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) GSQ19_19840 ENOG4105C72 UPF0176 protein GSQ19_19860 ENOG4105S6R Iron-hydroxamate transporter permease subunit GSQ19_19865 ENOG4105J76 Periplasmic binding protein GSQ19_19870 ENOG4105E0A ABC, transporter GSQ19_19910 ENOG4105DY8 decarboxylase GSQ19_19935 ENOG410902K Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) GSQ19_19950 ENOG4105D9P serine threonine protein kinase GSQ19_19995 ENOG4105C19 ABC transporter GSQ19_20030 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GSQ19_20035 ENOG4105C19 ABC transporter GSQ19_20040 ENOG4105D0S secretion protein (HlyD GSQ19_20045 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) GSQ19_20060 ENOG4105DVK Precorrin-2 c20-methyltransferase GSQ19_20065 ENOG41081F0 Precorrin-8x methylmutase GSQ19_20070 ENOG4105J0C GSQ19_20075 ENOG4108RMU ferritin dps family protein GSQ19_20095 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) GSQ19_20100 ENOG41068BY Low temperature-induced protein GSQ19_20165 ENOG4105EMU Dehydrogenase GSQ19_20175 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) GSQ19_20205 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) GSQ19_20210 ENOG4107U45 Cobalt transport protein GSQ19_20225 ENOG41080W8 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) GSQ19_20235 ENOG4105CQR helicase GSQ19_20260 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) GSQ19_20300 ENOG4105DXN mazG family GSQ19_20310 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_20315 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) GSQ19_20325 ENOG4105D7K pfkb domain protein GSQ19_20360 ENOG4106KF1 Phycobilisome protein GSQ19_20375 ENOG41078GB pbs lyase GSQ19_20380 ENOG4106TM1 PBS lyase HEAT-like repeat GSQ19_20385 ENOG4105D6V phycocyanin beta subunit GSQ19_20390 ENOG4108SDR phycocyanin, alpha subunit GSQ19_20395 ENOG4108MZQ phycobilisome linker polypeptide GSQ19_20405 ENOG41078GB pbs lyase GSQ19_20410 ENOG4108V9J phycocyanobilin lyase GSQ19_20415 ENOG4106BTU phycobilisome rod-core linker polypeptide GSQ19_20420 ENOG4106BTU phycobilisome rod-core linker polypeptide GSQ19_20430 ENOG4106Q05 Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity) GSQ19_20435 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GSQ19_20445 ENOG4105C26 Dehydrogenase GSQ19_20455 ENOG4105BZU Histidine kinase GSQ19_20460 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GSQ19_20470 ENOG4105D4Y metalloprotease GSQ19_20480 ENOG4107RAJ Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) GSQ19_20495 ENOG4105CE4 GlcNAc 6-P deacetylase GSQ19_20515 ENOG4105BZU Histidine kinase GSQ19_20535 ENOG4105E90 ABC transporter GSQ19_20540 ENOG4108IJ8 ABC transporter GSQ19_20560 ENOG4105CHR reductase GSQ19_20615 ENOG41087WU GSQ19_20645 ENOG41084M5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) GSQ19_20650 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) GSQ19_20675 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) GSQ19_20690 ENOG4108V5V Serine Threonine protein kinase GSQ19_20695 ENOG4108V5V Serine Threonine protein kinase GSQ19_20710 ENOG4105C31 Tryptophanyl-tRNA synthetase GSQ19_20745 ENOG4105EVB acetyltransferase GSQ19_20770 ENOG4108UXN response regulator GSQ19_20775 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) GSQ19_20790 ENOG4105BZU Histidine kinase GSQ19_20820 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) GSQ19_20830 ENOG4105BZ1 (ABC) transporter GSQ19_20845 ENOG4105C5H ABC transporter GSQ19_20855 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR GSQ19_20870 ENOG4105D9U N-acetyltransferase GSQ19_20910 ENOG4105BZU Histidine kinase GSQ19_20915 ENOG41083MR nifu domain-containing protein GSQ19_20930 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) GSQ19_20965 ENOG4107R1X phosphohexokinase GSQ19_20970 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) GSQ19_20975 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) GSQ19_21000 ENOG4107SC1 transglycosylase GSQ19_21070 ENOG4108K7V UPF0284 protein GSQ19_21080 ENOG4105DS0 Transcriptional regulator, Crp Fnr family GSQ19_21105 ENOG4105DU0 nucleoside hydrolase GSQ19_21115 ENOG4105C0H protease GSQ19_21120 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 GSQ19_21130 ENOG4105VN1 Heat shock protein GSQ19_21135 ENOG4105KPY Small multidrug resistance protein GSQ19_21140 ENOG4108HMN Caspase domain GSQ19_21145 ENOG4108HMN Caspase domain GSQ19_21155 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) GSQ19_21175 ENOG4105WVZ Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) GSQ19_21185 ENOG4105CKD glutathione-regulated potassium-efflux system protein GSQ19_21195 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) GSQ19_21200 ENOG4105BZU Histidine kinase GSQ19_21210 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) GSQ19_21250 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_21270 ENOG4105CPC Aldo Keto reductase GSQ19_21300 ENOG4105E2X shikimate dehydrogenase GSQ19_21315 ENOG4108VIA integral membrane protein GSQ19_21325 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) GSQ19_21345 ENOG4107S2Z UPF0761 membrane protein GSQ19_21365 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) GSQ19_21370 ENOG4108UYE Lactoylglutathione lyase GSQ19_21415 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) GSQ19_21440 ENOG4105VFU Rna-binding protein GSQ19_21445 ENOG4105CSR polyphosphate kinase 2 GSQ19_21455 ENOG4105RYY domain protein GSQ19_21495 ENOG4105D3G Pseudouridine synthase GSQ19_21535 ENOG4105D0M Protease HtpX homolog GSQ19_21555 ENOG4105CRK lysyL-tRNA synthetase GSQ19_21605 ENOG4105BZU Histidine kinase GSQ19_21640 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) GSQ19_21670 ENOG4105BZU Histidine kinase GSQ19_21685 ENOG4108IQE Amp-dependent synthetase and ligase GSQ19_21710 ENOG4108SHJ s-layer protein GSQ19_21725 ENOG4108NAW Type II site-specific deoxyribonuclease GSQ19_21755 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) GSQ19_21760 ENOG4105IJJ transcriptional regulator, crp fnr family GSQ19_21765 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) GSQ19_21785 ENOG4105DGU Histone deacetylase GSQ19_21790 ENOG4106PVI ATP-dependent carboxylate-amine ligase (By similarity) GSQ19_21800 ENOG4108K5P (LipO)protein GSQ19_21805 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) GSQ19_21810 ENOG4105D0M Protease HtpX homolog GSQ19_21815 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) GSQ19_21845 ENOG4105G5N sensor protein GSQ19_21855 ENOG4106KE4 Dehydrogenase GSQ19_21860 ENOG4105BZU Histidine kinase GSQ19_21865 ENOG4108PJD permease GSQ19_21920 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) GSQ19_21965 ENOG4105C12 Phosphoribosylglycinamide synthetase GSQ19_21970 ENOG4108IAJ Nad-dependent epimerase dehydratase GSQ19_21980 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase GSQ19_21985 ENOG4106YN8 Prenyltransferase GSQ19_21990 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSQ19_22000 ENOG4105BZU Histidine kinase GSQ19_22050 ENOG4105VDM plasmid maintenance system antidote protein, xre family GSQ19_22075 ENOG4105E6M Sulphatase-modifying factor protein GSQ19_22175 ENOG4107QTH restriction modification system DNA specificity domain GSQ19_22205 ENOG4108F3G Type I restriction-modification system, R subunit GSQ19_22215 ENOG4105CNF WD-40 repeat protein GSQ19_22215 ENOG4105CNF WD-40 repeat protein GSQ19_22225 ENOG4105C0D helicase GSQ19_22235 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) GSQ19_22250 ENOG4108R0D protein with myosin-like GSQ19_22255 ENOG4107RU9 Transcriptional regulator, Crp Fnr family GSQ19_22260 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH GSQ19_22265 ENOG4105ECC imidazole-glycerol-phosphate dehydratase GSQ19_22270 ENOG4105DA5 (ABC) transporter GSQ19_22290 ENOG4105CP7 Triose-phosphate isomerase GSQ19_22295 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) GSQ19_22325 ENOG4105D52 delta-aminolevulinic acid dehydratase GSQ19_22330 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) GSQ19_22335 ENOG4105D0M Protease HtpX homolog GSQ19_22345 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_22355 ENOG4105F23 Fibronectin-binding protein GSQ19_22365 ENOG4105ERG peptidase m48, ste24p GSQ19_22370 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) GSQ19_22380 ENOG4107WDG serine threonine protein kinase GSQ19_22390 ENOG4107WDG serine threonine protein kinase GSQ19_22395 ENOG4105CTK cobaltochelatase, cobn subunit GSQ19_22475 ENOG4107TCE N-acetyltransferase GSQ19_22490 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) GSQ19_22500 ENOG4105XCI PucC protein GSQ19_22505 ENOG4105ECY inositol monophosphatase GSQ19_22530 ENOG4105CHR reductase GSQ19_22540 ENOG4105IJJ transcriptional regulator, crp fnr family GSQ19_22545 ENOG4105DB3 bacteriochlorophyll chlorophyll a synthase GSQ19_22550 ENOG4105D0U Arsenite-activated ATPase (ArsA) GSQ19_22575 ENOG4105EY8 ABC transporter GSQ19_22580 ENOG4107RGC Glycosyl transferase, family 2 GSQ19_22585 ENOG4107RGC Glycosyl transferase, family 2 GSQ19_22595 ENOG4105CKK Glycosyl transferase, family 2 GSQ19_22600 ENOG4108IAJ Nad-dependent epimerase dehydratase GSQ19_22610 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase GSQ19_22615 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase GSQ19_22620 ENOG4107V9E glucose-1-phosphate thymidylyltransferase GSQ19_22635 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GSQ19_22640 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_22650 ENOG4105BZU Histidine kinase GSQ19_22665 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_22670 ENOG4108W3Y Transcriptional regulator, Crp Fnr family GSQ19_22680 ENOG4105EB3 Histidine kinase GSQ19_22685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_22700 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GSQ19_22725 ENOG4108UDB Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GSQ19_22730 ENOG4107SA8 fad-dependent pyridine nucleotide-disulfide oxidoreductase GSQ19_22750 ENOG4108ZF3 Phosphatase GSQ19_22770 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) GSQ19_22780 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) GSQ19_22785 ENOG4108302 MgtC SapB transporter GSQ19_22795 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GSQ19_22800 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GSQ19_22805 ENOG4108KS2 transglutaminase domain protein GSQ19_22825 ENOG4105CKK Glycosyl transferase, family 2 GSQ19_22830 ENOG4105C6X Major Facilitator GSQ19_22840 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) GSQ19_22855 ENOG410812K response regulator receiver protein GSQ19_22880 ENOG4107QRP cobalamin biosynthesis protein CobW GSQ19_22900 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) GSQ19_22935 ENOG4105E0Y RtcB Protein GSQ19_22940 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) GSQ19_22965 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) GSQ19_22970 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) GSQ19_22975 ENOG4107TS3 membrane protein, TerC GSQ19_22990 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GSQ19_22995 ENOG4105W8H transhydrogenase (subunit alpha GSQ19_23000 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) GSQ19_23015 ENOG41082ZZ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) GSQ19_23025 ENOG4107RIX inner membrane protein translocase component YidC GSQ19_23060 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) GSQ19_23065 ENOG4108R6B Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) GSQ19_23075 ENOG4105C0K Gdp-mannose 4,6-dehydratase GSQ19_23080 ENOG4105JNK Glycosyl transferase (Group 1 GSQ19_23090 ENOG41084A0 50s ribosomal protein L35 GSQ19_23095 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) GSQ19_23120 ENOG4105CK6 Two component transcriptional regulator (Winged helix family GSQ19_23130 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) GSQ19_23155 ENOG4105CYX Short-chain dehydrogenase reductase Sdr GSQ19_23160 ENOG4107QN2 dihydrolipoyl dehydrogenase GSQ19_23185 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) GSQ19_23190 ENOG4105EVY Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) GSQ19_23195 ENOG4105BZU Histidine kinase GSQ19_23230 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) GSQ19_23245 ENOG4107XW6 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) GSQ19_23255 ENOG41083CN Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) GSQ19_23265 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) GSQ19_23285 ENOG4108Z6M essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn GSQ19_23325 ENOG4108R5Z fruiting body developmental protein GSQ19_23330 ENOG4108YN7 fruiting body developmental protein GSQ19_23360 ENOG4105CVR type I restriction-modification system GSQ19_23360 ENOG4105CVR type I restriction-modification system GSQ19_23380 ENOG4105DZR Type I site-specific deoxyribonuclease GSQ19_23425 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) GSQ19_23435 ENOG4107S8C mandelate racemase muconate lactonizing GSQ19_23455 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase GSQ19_23460 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) GSQ19_23470 ENOG4105DWF phosphomethylpyrimidine kinase GSQ19_23515 ENOG4105BZU Histidine kinase GSQ19_23535 ENOG4105C9X ppx gppa phosphatase GSQ19_23550 ENOG4105C7K acetolactate synthase GSQ19_23560 ENOG4105D9P serine threonine protein kinase GSQ19_23565 ENOG4108JUA Transcriptional regulator GSQ19_23580 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) GSQ19_23590 ENOG4105BZU Histidine kinase GSQ19_23605 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) GSQ19_23615 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) GSQ19_23620 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) GSQ19_23625 ENOG4105F0N pyrophosphate phospho-hydrolase GSQ19_23655 ENOG4105EY5 This is one of the two reaction center proteins of photosystem II GSQ19_23660 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) GSQ19_23670 ENOG4108IJ0 Aspartate ammonia-lyase GSQ19_23680 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase GSQ19_23695 ENOG4105C75 arginyL-tRNA synthetase GSQ19_23735 ENOG4105CPK Glycosyl transferase (Group 1 GSQ19_23755 ENOG4105E2K Glycosyl transferase (Group 1 GSQ19_23800 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) GSQ19_23810 ENOG4105D9P serine threonine protein kinase GSQ19_23815 ENOG4105E67 Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings) GSQ19_23830 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) GSQ19_23875 ENOG4105D64 Mechanosensitive ion channel GSQ19_23880 ENOG4105D64 Mechanosensitive ion channel GSQ19_23920 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) GSQ19_23925 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) GSQ19_23930 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation GSQ19_23940 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) GSQ19_23955 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GSQ19_23975 ENOG41068G9 50S ribosomal protein L32 GSQ19_23985 ENOG4105C26 Dehydrogenase GSQ19_23990 ENOG4105BZU Histidine kinase GSQ19_24000 ENOG4105CQM Urea amidohydrolase subunit alpha GSQ19_24010 ENOG4105KI2 Urea amidohydrolase subunit beta GSQ19_24015 ENOG4108YZ9 Urea amidohydrolase subunit gamma GSQ19_24020 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) GSQ19_24045 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) GSQ19_24050 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) GSQ19_24065 ENOG4105C5S asparaginyl-tRNA synthetase GSQ19_24085 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) GSQ19_24090 ENOG4108S1Y allophycocyanin alpha-B chain GSQ19_24095 ENOG4107QIK phosphoribosylformylglycinamidine synthase GSQ19_24100 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase GSQ19_24125 ENOG4105CFH Aspartokinase GSQ19_24140 ENOG4105CV1 Transketolase (EC 2.2.1.1) GSQ19_24150 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) GSQ19_24155 ENOG41086B8 CoB-CoM heterodisulfide reductase GSQ19_24160 ENOG41086BQ Protein CrcB homolog GSQ19_24170 ENOG4105CVJ phosphoglycerate mutase GSQ19_24180 ENOG4108IAJ Nad-dependent epimerase dehydratase GSQ19_24205 ENOG4107QRT dEAD DEAH box helicase GSQ19_24215 ENOG4105CZX twitching motility protein GSQ19_24220 ENOG4108ZGN Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity) GSQ19_24260 ENOG4105BZU Histidine kinase GSQ19_24320 ENOG4108Z0R Transferase GSQ19_24330 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase GSQ19_24360 ENOG4105GVR general secretion pathway protein D GSQ19_24380 ENOG4105DJZ UPF0182 protein GSQ19_24390 ENOG4105CHM Aminotransferase GSQ19_24400 ENOG4105CBT Fructose-1,6-bisphosphatase GSQ19_24405 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) GSQ19_24420 ENOG4107YCR Transcriptional regulator, ARSR family GSQ19_24430 ENOG4105C0Z ABC transporter GSQ19_24435 ENOG4105CF8 branched-chain amino acid ABC transporter, permease GSQ19_24450 ENOG4105C89 phosphohexose isomerase GSQ19_24485 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase GSQ19_24495 ENOG4105CKI cobalamin synthesis protein GSQ19_24500 ENOG4105C8N cysteinyl-tRNA synthetase GSQ19_24510 ENOG4105CMS peptidase U62, modulator of DNA gyrase GSQ19_24515 ENOG4105BZU Histidine kinase GSQ19_24520 ENOG41082AN stage II sporulation protein GSQ19_24525 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_24550 ENOG4105MSA Photosystem II reaction center W protein GSQ19_24560 ENOG4105C8Y Acetylornithine aminotransferase GSQ19_24570 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) GSQ19_24580 ENOG4105FDP GntR family transcriptional regulator GSQ19_24585 ENOG4105F8J Adenylate Guanylate cyclase GSQ19_24620 ENOG4105DGI Alkaline phosphatase GSQ19_24640 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase GSQ19_24650 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) GSQ19_24680 ENOG4105C71 hydrolase family 65, central catalytic GSQ19_24685 ENOG4107STW synthase GSQ19_24695 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) GSQ19_24725 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) GSQ19_24750 ENOG4105ESV Glycosyl transferase, family 4 GSQ19_24755 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) GSQ19_24760 ENOG4105EWN Heme oxygenase GSQ19_24765 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) GSQ19_24770 ENOG4105CKX Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP GSQ19_24780 ENOG4107QJE Chromosome Partitioning Protein GSQ19_24790 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) GSQ19_24795 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) GSQ19_24800 ENOG4105M3Z response regulator GSQ19_24815 ENOG4105CBS Chea signal transduction histidine kinase GSQ19_24825 ENOG4105EUB pirin domain protein GSQ19_24830 ENOG4107XNQ Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) GSQ19_24835 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit GSQ19_24845 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) GSQ19_24905 ENOG41089UC methyltransferase, type 11 GSQ19_24910 ENOG4105CJ3 phosphate transporter GSQ19_24935 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) GSQ19_24945 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase GSQ19_24950 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) GSQ19_25010 ENOG4105DC1 bifunctional purine biosynthesis protein purh GSQ19_25015 ENOG4105BZU Histidine kinase GSQ19_25025 ENOG4105WEF catalase GSQ19_25030 ENOG4105Y3U Transglycosylase-associated protein GSQ19_25035 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) GSQ19_25040 ENOG4105EBH Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity) GSQ19_25085 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate GSQ19_25095 ENOG41072GX Peptidase M22 Glycoprotease GSQ19_25100 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) GSQ19_25135 ENOG4107CUI carotenoid binding protein GSQ19_25145 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) GSQ19_25155 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_25160 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_25165 ENOG4105ES5 Histidine kinase GSQ19_25175 ENOG4105BZU Histidine kinase GSQ19_25205 ENOG4108KK4 3-dehydroquinate synthase GSQ19_25210 ENOG4105C59 p-type ATPase GSQ19_25215 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) GSQ19_25225 ENOG41081F0 Precorrin-8x methylmutase GSQ19_25230 ENOG4105DSF transport protein GSQ19_25245 ENOG4105BZU Histidine kinase GSQ19_25250 ENOG4105KAN Probably a ribosomal protein or a ribosome-associated protein (By similarity) GSQ19_25260 ENOG4105BZU Histidine kinase GSQ19_25295 ENOG4106WTF Glycosyl transferase, family 2 GSQ19_25300 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF GSQ19_25320 ENOG4107YBR Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) GSQ19_25325 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen GSQ19_25335 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) GSQ19_25350 ENOG4105E5Q amino acid AbC transporter GSQ19_25365 ENOG41075E2 Photosystem I reaction centre subunit IX / PsaJ GSQ19_25375 ENOG41081AP Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) GSQ19_25380 ENOG4108PPB Seems to be required for the assembly of the photosystem I complex (By similarity) GSQ19_25385 ENOG4108RAV Conserved protein GSQ19_25390 ENOG4108K3A Glutathione S-transferase GSQ19_25395 ENOG41063C6 UPF0235 protein GSQ19_25410 ENOG4105H0Z Hemerythrin HHE cation binding domain protein GSQ19_25440 ENOG41067S7 ribulose bisphosphate carboxylase GSQ19_25455 ENOG4108VFZ ribulose bisphosphate carboxylase, small GSQ19_25465 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate GSQ19_25475 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) GSQ19_25485 ENOG4107R7I amino acid GSQ19_25500 ENOG4108AC1 4fe-4s ferredoxin, iron-sulfur binding GSQ19_25505 ENOG4105C3J Cysteine desulfurase GSQ19_25515 ENOG4105DSM The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity) GSQ19_25520 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_25545 ENOG4105JZI cytochrome P450 GSQ19_25550 ENOG4108S59 GSQ19_25585 ENOG4105CY9 nitrogenase molybdenum-iron protein beta chain GSQ19_25595 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_25600 ENOG4105DK8 Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN GSQ19_25605 ENOG4108UR2 Nitrogen fixation protein NifX GSQ19_25610 ENOG4108VQE nitrogen fixation protein GSQ19_25615 ENOG4105X87 nitrogen fixation GSQ19_25620 ENOG4105R88 May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity) GSQ19_25625 ENOG41081QJ UBA THIF-type NAD FAD binding GSQ19_25630 ENOG4105V5Z Iron-sulfur cluster assembly accessory protein GSQ19_25645 ENOG4105F4R Transcriptional regulator mode GSQ19_25700 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) GSQ19_25720 ENOG4107S73 homocitrate synthase GSQ19_25755 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) GSQ19_25770 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) GSQ19_25775 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) GSQ19_25780 ENOG4108W6C Dehydrogenase GSQ19_25785 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) GSQ19_25795 ENOG4108RU0 short-chain dehydrogenase reductase GSQ19_25820 ENOG4105BZU Histidine kinase GSQ19_25825 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase GSQ19_25845 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase GSQ19_25870 ENOG4107EEY synthase GSQ19_25880 ENOG4105CEY Amp-dependent synthetase and ligase GSQ19_25885 ENOG4105C84 Histidine ammonia-lyase GSQ19_25935 ENOG4105D9P serine threonine protein kinase GSQ19_25940 ENOG4105CGH 5'-nucleotidase GSQ19_26020 ENOG4107VE4 peptidase S8 and S53, subtilisin, kexin, sedolisin GSQ19_26045 ENOG4105DFK Polyphosphate glucokinase GSQ19_26055 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) GSQ19_26060 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) GSQ19_26065 ENOG4106H78 methyltransferase GSQ19_26090 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) GSQ19_26095 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) GSQ19_26110 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_26115 ENOG4105CY9 nitrogenase molybdenum-iron protein beta chain GSQ19_26120 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_26160 ENOG4108DBC nitroreductase GSQ19_26170 ENOG4105XEA Tetr family transcriptional regulator GSQ19_26175 ENOG4108JJB ABC transporter GSQ19_26190 ENOG4107S73 homocitrate synthase GSQ19_26195 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family GSQ19_26220 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GSQ19_26225 ENOG4105C4M (Ubiquinol oxidase) subunit I GSQ19_26240 ENOG4105D0B Nitrogenase protein alpha chain GSQ19_26245 ENOG4108UR2 Nitrogen fixation protein NifX GSQ19_26275 ENOG4108VJC ABC transporter, periplasmic molybdate-binding protein GSQ19_26280 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_26300 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) GSQ19_26310 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) GSQ19_26315 ENOG4105GVF (ABC) transporter GSQ19_26510 ENOG4105CNF WD-40 repeat protein GSQ19_26520 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_26530 ENOG4105EKQ RNA-directed DNA polymerase GSQ19_26600 ENOG4105EWM Histidine kinase GSQ19_26605 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_26640 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSQ19_26755 ENOG4105C01 Dihydroxy-acid dehydratase GSQ19_26785 ENOG4107RSM transcriptional regulator GSQ19_26790 ENOG4105CFI type iii restriction protein res subunit GSQ19_26895 ENOG4106H3A restriction GSQ19_26940 ENOG4105D7V transposase GSQ19_26965 ENOG4105CHH sulfate transporter GSQ19_26975 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic GSQ19_27005 ENOG4105D1H recombination factor protein RarA GSQ19_27095 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding GSQ19_27105 ENOG4108M24 von Willebrand factor, type A GSQ19_27150 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_27155 ENOG4105E0R Deoxyhypusine synthase GSQ19_27165 ENOG4105CA0 peroxidase GSQ19_27190 ENOG4105CNM Receptor GSQ19_27195 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GSQ19_27200 ENOG4105EHG Permease protein GSQ19_27205 ENOG4105E0A ABC, transporter GSQ19_27240 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) GSQ19_27250 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) GSQ19_27255 ENOG4105EHG Permease protein GSQ19_27260 ENOG4105E0A ABC, transporter GSQ19_27270 ENOG4105C8Y Acetylornithine aminotransferase GSQ19_27275 ENOG4105E0R Deoxyhypusine synthase GSQ19_27290 ENOG4105CE1 Ferrous iron transport protein b GSQ19_27305 ENOG4105C4M (Ubiquinol oxidase) subunit I GSQ19_27310 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii GSQ19_27320 ENOG4105C4M (Ubiquinol oxidase) subunit I GSQ19_27370 ENOG4107ZSV Receptor GSQ19_27390 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_27400 ENOG4105BZU Histidine kinase GSQ19_27445 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_27465 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) GSQ19_27475 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_27480 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) GSQ19_27485 ENOG4105ES5 Histidine kinase GSQ19_27490 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_27505 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GSQ19_27515 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSQ19_27530 ENOG4105E0K tonB-dependent siderophore receptor GSQ19_27535 ENOG4105E0K tonB-dependent siderophore receptor GSQ19_27560 ENOG4105FDK ABC transporter GSQ19_27565 ENOG4105DSE periplasmic solute binding protein GSQ19_27570 ENOG4105D52 delta-aminolevulinic acid dehydratase GSQ19_27575 ENOG4105C22 threonyL-tRNA synthetase GSQ19_27585 ENOG4105CKI cobalamin synthesis protein GSQ19_27590 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) GSQ19_27640 ENOG4108JJA ABC, transporter GSQ19_27650 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_27665 ENOG4105C7H Helicase, RecD TraA family GSQ19_27870 ENOG4105C0D helicase GSQ19_27870 ENOG4105C0D helicase GSQ19_27885 ENOG4105D7V transposase GSQ19_27930 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family GSQ19_27970 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation GSQ19_27985 ENOG4105C3J Cysteine desulfurase GSQ19_27995 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) GSQ19_28000 ENOG4105CFI type iii restriction protein res subunit GSQ19_28105 ENOG4105CDU Replicative dna helicase GSQ19_28195 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_28320 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) GSQ19_28330 ENOG4105DPZ Two component transcriptional regulator (Winged helix family GSQ19_28365 ENOG4105BZU Histidine kinase GSQ19_28385 ENOG4108J5G 6-phosphogluconate dehydrogenase GSQ19_28405 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase GSQ19_28420 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) GSQ19_28440 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GSQ19_28450 ENOG4105J0C GSQ19_28460 ENOG4105CV8 reductase GSQ19_28485 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit GSQ19_28505 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit GSQ19_28510 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding GSQ19_28515 ENOG4105C7W Xanthine dehydrogenase GSQ19_28520 ENOG4105XRQ Xanthine dehydrogenase accessory factor GSQ19_28525 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) GSQ19_28530 ENOG4105FA0 parb-like partition protein GSQ19_28540 ENOG4107QJE Chromosome Partitioning Protein GSQ19_28560 ENOG4105D9P serine threonine protein kinase GSQ19_28565 ENOG4105WH1 Two component transcriptional regulator luxr family GSQ19_28570 ENOG4105CF7 AraC family transcriptional regulator GSQ19_28585 ENOG4105EMU Dehydrogenase GSQ19_28590 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) GSQ19_28605 ENOG41061TZ Short-chain dehydrogenase reductase Sdr GSQ19_28635 ENOG4105CHJ isochorismatase hydrolase GSQ19_28675 ENOG4107FCW Abortive infection protein GSQ19_28720 ENOG4105K70 DNA-binding protein GSQ19_28750 ENOG4105FA2 dna polymerase iii GSQ19_28785 ENOG4105C6E dna polymerase iii GSQ19_28810 ENOG4105D7V transposase GSQ19_28865 ENOG4108I5C dEAD DEAH box helicase GSQ19_28875 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) GSQ19_29005 ENOG4105EKQ RNA-directed DNA polymerase GSQ19_29020 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) GSQ19_29035 ENOG41075H3 AraC family transcriptional regulator GSQ19_29055 ENOG4108PWY Carbohydrate-selective porin OprB GSQ19_29090 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) GSQ19_29100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component GSQ19_29115 ENOG4105E0K tonB-dependent siderophore receptor GSQ19_29150 ENOG4105EV8 ectoine hydroxylase GSQ19_29240 ENOG4105C0D helicase GSQ19_29355 ENOG4105DR5 peptidase GSQ19_29395 ENOG4108ZF3 Phosphatase GSQ19_29420 ENOG4105CDU Replicative dna helicase GSQ19_29420 ENOG4105CDU Replicative dna helicase GSQ19_29455 ENOG4107QJE Chromosome Partitioning Protein GSQ19_29460 ENOG4105FA0 parb-like partition protein GSQ19_29525 ENOG4107WDG serine threonine protein kinase GSQ19_29540 ENOG4108I7H Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) GSQ19_29595 ENOG4107QJE Chromosome Partitioning Protein GSQ19_29600 ENOG4105FA0 parb-like partition protein