locus-tag	class	description
TW002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TW005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TW006	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TW008	ENOG4105FJ0	thiamine
TW009	ENOG4107U91	Rhomboid family
TW012	ENOG4108V0P	LemA family
TW017	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
TW020	ENOG4108JIK	carboxylase
TW025	ENOG4105D8K	carboxyl transferase
TW035	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
TW038	ENOG4105EY8	ABC transporter
TW042	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TW055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TW060	ENOG4105EVN	Prephenate dehydrogenase
TW061	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TW062	ENOG4105E4F	Isochorismate synthase
TW068	ENOG4105E0A	ABC, transporter
TW069	ENOG4105TVJ	transport system, permease
TW070	ENOG4105DQ5	transport system permease protein
TW071	ENOG41082SX	arsR family transcriptional regulator
TW072	ENOG4105DK7	lysyl-tRNA synthetase
TW074	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TW075	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TW078	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
TW084	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TW085	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TW086	ENOG4107QVP	Dehydrogenase
TW093	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TW094	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TW098	ENOG4105DZP	Membrane-associated zinc metalloprotease
TW100	ENOG4108ZF3	Phosphatase
TW106	ENOG4105CJ1	ABC, transporter
TW108	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TW120	ENOG4107SIQ	Naphthoate synthase
TW128	ENOG4108426	dNA-binding protein
TW132	ENOG4105FF9	glycosyl transferase, family 39
TW133	ENOG4105EIP	mannose-6-phosphate isomerase
TW134	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
TW137	ENOG4107QKV	phosphomannomutase
TW148	ENOG4108JJB	ABC transporter
TW150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TW153	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TW156	ENOG4105CS9	pantothenic acid kinase
TW162	ENOG4105BZ1	(ABC) transporter
TW163	ENOG4105BZ1	(ABC) transporter
TW166	ENOG4105CI3	gtp-binding protein typa
TW167	ENOG4108097	ATP-binding protein
TW172	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TW173	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TW174	ENOG4105EUJ	GTP cyclohydrolase i
TW175	ENOG4105EEI	dihydropteroate synthase
TW177	ENOG4108IUZ	ABC transporter
TW180	ENOG4105DTN	riboflavin biosynthesis protein ribF
TW187	ENOG4108Z4U	Ferredoxin
TW190	ENOG4108VQJ	O-methyltransferase
TW201	ENOG4105C32	Amino acid ABC transporter (Permease)
TW202	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TW203	ENOG4105C0Z	ABC transporter
TW204	ENOG4108IV0	ABC, transporter
TW205	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TW209	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TW225	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TW227	ENOG4105F0I	Aminotransferase
TW237	ENOG4105CJW	magnesium transporter
TW238	ENOG4107T6F	Xaa-Pro aminopeptidase
TW243	ENOG4105C4R	Atp-dependent dna helicase
TW247	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TW249	ENOG4107VQS	DivIVA family
TW253	ENOG4105DU1	integral membrane protein, terc
TW254	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TW255	ENOG4107RIS	Acyl-transferase
TW262	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TW263	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TW266	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TW267	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TW268	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TW272	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TW273	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TW281	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TW284	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TW288	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TW290	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TW291	ENOG4105C03	ribonuclease
TW302	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TW303	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TW305	ENOG41082KU	UPF0109 protein
TW306	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TW313	ENOG4105C0P	Mg chelatase subunit ChlI
TW314	ENOG4105C79	DNA protecting protein DprA
TW315	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TW322	ENOG4105KNE	Phosphatidate cytidylyltransferase
TW329	ENOG4105D6E	homoserine dehydrogenase
TW330	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TW331	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TW333	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TW334	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TW336	ENOG4105ESV	Glycosyl transferase, family 4
TW338	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
TW343	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TW345	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TW348	ENOG4105PGM	cation diffusion facilitator family transporter
TW352	ENOG4107QI6	Cysteine desulfurase
TW355	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TW361	ENOG4105BZ1	(ABC) transporter
TW372	ENOG4105MC2	DSBA oxidoreductase
TW376	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
TW384	ENOG4105CRQ	synthase (Component I)
TW386	ENOG4105KQC	Competence protein
TW396	ENOG4105E2X	shikimate dehydrogenase
TW398	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TW400	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TW402	ENOG4105CD3	dihydroorotase
TW403	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TW404	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TW405	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
TW411	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TW415	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
TW421	ENOG4108VJ1	Transcriptional regulator (CarD family
TW429	ENOG4105C89	phosphohexose isomerase
TW430	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TW433	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
TW434	ENOG4105DIW	FeS assembly protein SUFB
TW437	ENOG4105C3K	feS assembly ATPase SufC
TW438	ENOG4105VG1	fes assembly suf system protein
TW442	ENOG4108HWW	ABC transporter
TW443	ENOG4105DFW	ABC transporter
TW445	ENOG4105CPQ	Dehydrogenase
TW446	ENOG4105F8V	Hydrolase, tatD family
TW450	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
TW451	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TW459	ENOG4105CHR	reductase
TW464	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
TW465	ENOG4105F0N	pyrophosphate phospho-hydrolase
TW472	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TW473	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TW476	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TW478	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TW480	ENOG4105C2M	dna polymerase I
TW482	ENOG4105CA9	Pyruvate kinase
TW483	ENOG4105K4H	Nlp p60 protein
TW485	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TW486	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TW487	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
TW491	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TW496	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TW498	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TW502	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TW503	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TW504	ENOG4105CDY	transcriptional regulatory protein
TW513	ENOG4105EGD	dinuclear metal center protein, YbgI family
TW515	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TW521	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TW522	ENOG4107EUI	c reductase, iron-sulfur
TW523	ENOG4107UDY	cytochrome C
TW524	ENOG4105CCU	oxidase (Subunit III)
TW526	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TW527	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TW529	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TW532	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TW541	ENOG4105DFU	Cell wall formation (By similarity)
TW543	ENOG4105CNI	cell division protein FtsW
TW548	ENOG4105CJN	penicillin-binding protein
TW554	ENOG4105EAH	synthase
TW556	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
TW558	ENOG4105DKQ	ROK family
TW560	ENOG4107ZYJ	bioY protein
TW562	ENOG4105C3M	thioredoxin reductase
TW564	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TW566	ENOG4108ZP8	Acetolactate synthase small subunit
TW569	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TW573	ENOG4105CAK	Cell division ATP-binding protein ftsE
TW574	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TW576	ENOG4105CXT	aspartate transcarbamylase
TW585	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TW592	ENOG4108M15	ABC transporter
TW594	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TW610	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
TW618	ENOG4105F0N	pyrophosphate phospho-hydrolase
TW620	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TW626	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TW632	ENOG4105CN5	Metallo-Beta-Lactamase
TW633	ENOG4107V6K	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TW636	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
TW643	ENOG4105C0H	protease
TW647	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
TW648	ENOG4107QJE	Chromosome Partitioning Protein
TW656	ENOG4106H78	methyltransferase
TW659	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TW661	ENOG4105C3G	gtp-binding protein
TW666	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TW667	ENOG4105DJB	Major Facilitator Superfamily
TW684	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TW685	ENOG4105NXV	High-affinity zinc uptake system protein
TW686	ENOG4105DIK	(ABC) transporter
TW687	ENOG4105CC5	ABC transporter
TW699	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TW700	ENOG4105C7B	Threonine dehydratase
TW701	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TW702	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TW707	ENOG4108R6K	riboflavin synthase, subunit alpha
TW708	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TW711	ENOG4108RWI	nicotinamidase
TW713	ENOG4105C6E	dna polymerase iii
TW715	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TW721	ENOG4105KME	endoribonuclease L-psp
TW722	ENOG4105BZ4	penicillin-binding protein
TW725	ENOG4105CFH	Aspartokinase
TW732	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TW737	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TW738	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TW739	ENOG4105C12	Phosphoribosylglycinamide synthetase
TW746	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TW748	ENOG4107JTW	chlorite dismutase
TW751	ENOG4107TCW	O-succinylbenzoate synthase
TW752	ENOG4105CDU	Replicative dna helicase
TW756	ENOG4105CGK	Exodeoxyribonuclease III
TW759	ENOG4105KNI	merR family transcriptional Regulator
TW763	ENOG4108Z6B	deaminase
TW766	ENOG4105C5S	asparaginyl-tRNA synthetase
TW767	ENOG4108RH7	phosphoglycerate mutase
TW768	ENOG4105K63	Thioredoxin
TW769	ENOG4107QIV	Cytochrome c biogenesis protein
TW770	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
TW771	ENOG4105CRE	cytochrome C
TW773	ENOG4105CC5	ABC transporter
TW775	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TW777	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TW781	ENOG4105C9K	Endothelin-converting enzyme 1
TW782	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TW787	ENOG4105CJN	penicillin-binding protein
TW788	ENOG4107TPY	serine threonine protein kinase
TW789	ENOG4105D9P	serine threonine protein kinase
TW797	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
TW798	ENOG4105CPP	Dehydrogenase, E1 component
TW805	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
TW807	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TW808	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
TW810	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TW811	ENOG4105FA0	parb-like partition protein
TW812	ENOG4107QJE	Chromosome Partitioning Protein
TW813	ENOG4105C59	p-type ATPase