TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 Pfam PF01795 MraW methylase family 3 301 7.1E-101 T 18-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 SUPERFAMILY SSF81799 111 210 9.16E-33 T 18-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 PIRSF PIRSF004486 1 303 4.4E-112 T 18-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 Gene3D G3DSA:1.10.150.170 109 212 5.5E-92 T 18-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 302 35.326 T 18-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 SUPERFAMILY SSF53335 4 302 2.65E-34 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 301 4.4E-89 T 18-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TWT_220 f3a064f9b38d66bceb075c8f69304a38 317 Gene3D G3DSA:3.40.50.150 4 298 5.5E-92 T 18-10-2018 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 264 370 3.37E-30 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 4 187 4.71E-40 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 165 262 2.47E-23 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 449 42.504 T 18-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 260 3.2E-14 T 18-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 1 158 5.1E-41 T 18-10-2018 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.0E-12 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 117 1.0E-12 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 1.0E-12 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 372 2.7E-33 T 18-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 181 369 2.6E-64 T 18-10-2018 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF55957 364 450 1.44E-15 T 18-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 6.7E-160 T 18-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.30.310.50 377 452 6.2E-19 T 18-10-2018 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 408 438 9.3E-8 T 18-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 18-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 263 346 2.6E-64 T 18-10-2018 TWT_146 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 144 1.5E-33 T 18-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 18-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF69075 340 427 4.18E-6 T 18-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 5 158 7.6E-36 T 18-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 PIRSF PIRSF000445 1 442 9.2E-110 T 18-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 345 427 1.2E-5 T 18-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF69742 2 160 6.15E-36 T 18-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 173 267 1.7E-6 T 18-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Gene3D G3DSA:3.30.460.30 1 160 5.6E-40 T 18-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Gene3D G3DSA:3.40.50.720 164 329 6.0E-30 T 18-10-2018 TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF51735 169 263 1.41E-7 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_736 73153747fb3fddd1bc14b11a4a2a8ba7 447 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 428 20.632 T 18-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TWT_708 85720a00ddfde507732320a7e81510e0 418 Gene3D G3DSA:3.30.70.260 260 339 5.3E-45 T 18-10-2018 TWT_708 85720a00ddfde507732320a7e81510e0 418 Gene3D G3DSA:3.30.70.260 257 404 5.3E-45 T 18-10-2018 TWT_708 85720a00ddfde507732320a7e81510e0 418 Pfam PF00696 Amino acid kinase family 3 229 3.7E-51 T 18-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TWT_708 85720a00ddfde507732320a7e81510e0 418 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 18-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_708 85720a00ddfde507732320a7e81510e0 418 SUPERFAMILY SSF53633 4 243 5.5E-68 T 18-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TWT_708 85720a00ddfde507732320a7e81510e0 418 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 403 4.5E-103 T 18-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_708 85720a00ddfde507732320a7e81510e0 418 SUPERFAMILY SSF55021 247 326 1.88E-12 T 18-10-2018 TWT_708 85720a00ddfde507732320a7e81510e0 418 Gene3D G3DSA:3.40.1160.10 1 256 7.0E-82 T 18-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TWT_708 85720a00ddfde507732320a7e81510e0 418 PIRSF PIRSF000726 54 411 3.6E-111 T 18-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_708 85720a00ddfde507732320a7e81510e0 418 PIRSF PIRSF000726 1 62 6.6E-16 T 18-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_708 85720a00ddfde507732320a7e81510e0 418 SUPERFAMILY SSF55021 330 405 1.83E-17 T 18-10-2018 TWT_624 313686a29dcf64dc9e78e2e6c5ac502e 689 Pfam PF05345 Putative Ig domain 524 567 6.7E-7 T 18-10-2018 IPR008009 Putative Ig TWT_624 313686a29dcf64dc9e78e2e6c5ac502e 689 Pfam PF05345 Putative Ig domain 421 465 2.2E-11 T 18-10-2018 IPR008009 Putative Ig TWT_624 313686a29dcf64dc9e78e2e6c5ac502e 689 Pfam PF07861 WisP family N-Terminal Region 37 272 1.0E-156 T 18-10-2018 IPR012503 WisP, N-terminal TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 226 4.7E-81 T 18-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 Pfam PF00696 Amino acid kinase family 5 211 7.3E-27 T 18-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 Gene3D G3DSA:3.40.1160.10 1 231 7.0E-66 T 18-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 SUPERFAMILY SSF53633 3 228 1.1E-59 T 18-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 PIRSF PIRSF005650 1 231 8.3E-80 T 18-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TWT_447 df5cfa92f3e5533b8d30744fca78efd9 231 Hamap MF_01220_B Uridylate kinase [pyrH]. 1 230 38.351 T 18-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TWT_251 d7cb610cf748790487c1237487201295 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 4.0E-43 T 18-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TWT_251 d7cb610cf748790487c1237487201295 411 Gene3D G3DSA:3.40.47.10 255 399 3.1E-44 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_251 d7cb610cf748790487c1237487201295 411 Gene3D G3DSA:3.40.47.10 1 253 3.2E-68 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_251 d7cb610cf748790487c1237487201295 411 SUPERFAMILY SSF53901 213 408 2.34E-60 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_251 d7cb610cf748790487c1237487201295 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 6.8E-33 T 18-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TWT_251 d7cb610cf748790487c1237487201295 411 SMART SM00825 Beta-ketoacyl synthase 5 401 3.0E-12 T 18-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TWT_251 d7cb610cf748790487c1237487201295 411 SUPERFAMILY SSF53901 3 250 4.76E-56 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 Pfam PF00731 AIR carboxylase 17 162 7.8E-61 T 18-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 SMART SM01001 15 169 1.0E-80 T 18-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 17 168 28.65 T 18-10-2018 IPR033747 Class I PurE TWT_027 c93a785326f06ad57e3a9124d5de1949 180 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 17 171 6.2E-59 T 18-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 SUPERFAMILY SSF52255 16 172 4.06E-59 T 18-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 PIRSF PIRSF001338 13 180 3.4E-61 T 18-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TWT_027 c93a785326f06ad57e3a9124d5de1949 180 Gene3D G3DSA:3.40.50.7700 11 180 2.5E-63 T 18-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 47 111 5.4E-15 T 18-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 SUPERFAMILY SSF52540 115 395 1.9E-94 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 17 525 46.888 T 18-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Gene3D G3DSA:2.40.30.20 18 112 4.7E-22 T 18-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Gene3D G3DSA:3.40.50.300 113 396 4.4E-116 T 18-10-2018 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 SUPERFAMILY SSF50615 41 113 4.97E-20 T 18-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 168 389 5.8E-69 T 18-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 396 520 5.6E-41 T 18-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 Gene3D G3DSA:1.20.150.20 397 523 1.3E-41 T 18-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 20 523 1.2E-231 T 18-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 380 389 - T 18-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_426 11074c1d2d3df2dd2b76f0fbfdae8565 554 SUPERFAMILY SSF47917 397 523 9.68E-41 T 18-10-2018 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 SUPERFAMILY SSF56796 21 330 7.33E-82 T 18-10-2018 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 PIRSF PIRSF001455 1 377 3.0E-93 T 18-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 379 55.663 T 18-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 Gene3D G3DSA:1.20.1090.10 168 377 8.3E-48 T 18-10-2018 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 Pfam PF01761 3-dehydroquinate synthase 62 327 4.1E-89 T 18-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 26 330 3.2E-96 T 18-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TWT_370 30f3332edf733ef53f8218b7db7f28ae 380 Gene3D G3DSA:3.40.50.1970 2 167 6.4E-47 T 18-10-2018 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 SMART SM00729 93 299 8.6E-12 T 18-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 TIGRFAM TIGR00510 lipA: lipoyl synthase 42 328 1.2E-100 T 18-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 SUPERFAMILY SSF102114 60 318 7.06E-60 T 18-10-2018 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 Pfam PF04055 Radical SAM superfamily 102 257 1.8E-10 T 18-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 PIRSF PIRSF005963 1 344 3.3E-129 T 18-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 Hamap MF_00206 Lipoyl synthase [lipA]. 46 329 128.671 T 18-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 Gene3D G3DSA:3.20.20.70 96 304 1.1E-17 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_464 5130b9de4e9ad3be8b7ce2c9ec088069 354 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 46 82 1.9E-6 T 18-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 Gene3D G3DSA:3.90.1030.10 5 116 7.1E-36 T 18-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 22.96 T 18-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 Pfam PF01196 Ribosomal protein L17 21 116 6.7E-30 T 18-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 18-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 SUPERFAMILY SSF64263 5 116 2.09E-38 T 18-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_527 8d934d9dd5aea8c157a028c47d92eb96 179 TIGRFAM TIGR00059 L17: ribosomal protein bL17 15 116 9.3E-32 T 18-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 SUPERFAMILY SSF50465 301 396 1.47E-32 T 18-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 SUPERFAMILY SSF50447 208 304 1.98E-30 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Gene3D G3DSA:2.40.30.10 341 396 1.0E-25 T 18-10-2018 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 SUPERFAMILY SSF52540 9 229 9.4E-59 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 1.9E-17 T 18-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 2.3E-29 T 18-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 5.0E-212 T 18-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 PRINTS PR00315 GTP-binding elongation factor signature 97 108 5.3E-24 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 PRINTS PR00315 GTP-binding elongation factor signature 134 143 5.3E-24 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 PRINTS PR00315 GTP-binding elongation factor signature 61 69 5.3E-24 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.3E-24 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 PRINTS PR00315 GTP-binding elongation factor signature 81 91 5.3E-24 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 57.582 T 18-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Gene3D G3DSA:2.40.30.10 209 337 6.6E-51 T 18-10-2018 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 3.8E-12 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Gene3D G3DSA:3.40.50.300 1 206 5.2E-68 T 18-10-2018 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 1.7E-56 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_120 341bf61e34ce612741fb694f5fc6e4db 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 18-10-2018 IPR031157 Tr-type G domain, conserved site TWT_562 9b043ea40627713467e5e1f92d89056c 223 Pfam PF14622 Ribonuclease-III-like 19 141 1.5E-35 T 18-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TWT_562 9b043ea40627713467e5e1f92d89056c 223 SMART SM00358 158 219 4.5E-16 T 18-10-2018 IPR014720 Double-stranded RNA-binding domain TWT_562 9b043ea40627713467e5e1f92d89056c 223 Gene3D G3DSA:1.10.1520.10 5 149 3.5E-43 T 18-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TWT_562 9b043ea40627713467e5e1f92d89056c 223 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 215 27.044 T 18-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TWT_562 9b043ea40627713467e5e1f92d89056c 223 ProSitePatterns PS00517 Ribonuclease III family signature. 41 49 - T 18-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TWT_562 9b043ea40627713467e5e1f92d89056c 223 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 19 217 3.9E-62 T 18-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TWT_562 9b043ea40627713467e5e1f92d89056c 223 SUPERFAMILY SSF54768 113 218 1.07E-19 T 18-10-2018 TWT_562 9b043ea40627713467e5e1f92d89056c 223 SMART SM00535 19 152 2.8E-50 T 18-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TWT_562 9b043ea40627713467e5e1f92d89056c 223 SUPERFAMILY SSF69065 14 150 2.62E-43 T 18-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TWT_562 9b043ea40627713467e5e1f92d89056c 223 Pfam PF00035 Double-stranded RNA binding motif 158 218 1.1E-11 T 18-10-2018 IPR014720 Double-stranded RNA-binding domain TWT_562 9b043ea40627713467e5e1f92d89056c 223 Gene3D G3DSA:3.30.160.20 156 221 1.6E-17 T 18-10-2018 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 35 383 3.0E-102 T 18-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 167 183 - T 18-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 48 57 - T 18-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 32 385 39.768 T 18-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 33 383 1.3E-108 T 18-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 SUPERFAMILY SSF51726 33 383 3.31E-88 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_735 4c099d70fe036246d9ebb4f40a7a73a2 385 Gene3D G3DSA:3.20.20.210 23 385 3.9E-123 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 5 478 30.114 T 18-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 1.9E-22 T 18-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 1.9E-22 T 18-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 1.9E-22 T 18-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 202 1.9E-22 T 18-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 216 1.9E-22 T 18-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 SUPERFAMILY SSF52374 6 316 6.7E-92 T 18-10-2018 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:1.10.10.350 385 480 6.9E-19 T 18-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 6 478 9.9E-128 T 18-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 SUPERFAMILY SSF48163 318 477 1.01E-29 T 18-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:3.90.800.10 75 193 1.2E-87 T 18-10-2018 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 321 3.6E-76 T 18-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:3.40.50.620 6 246 1.2E-87 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_209 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:1.10.1160.10 250 333 4.0E-24 T 18-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 TWT_145 144c527b13d8475c29f58d21dca291f5 154 Pfam PF00380 Ribosomal protein S9/S16 33 154 6.1E-45 T 18-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TWT_145 144c527b13d8475c29f58d21dca291f5 154 Gene3D G3DSA:3.30.230.10 28 154 8.7E-49 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_145 144c527b13d8475c29f58d21dca291f5 154 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 24 154 32.37 T 18-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid TWT_145 144c527b13d8475c29f58d21dca291f5 154 SUPERFAMILY SSF54211 31 154 6.07E-44 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_145 144c527b13d8475c29f58d21dca291f5 154 ProSitePatterns PS00360 Ribosomal protein S9 signature. 92 110 - T 18-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 SUPERFAMILY SSF55200 78 162 4.19E-26 T 18-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 Gene3D G3DSA:3.10.20.80 1 69 5.6E-27 T 18-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 164 24.494 T 18-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 Gene3D G3DSA:3.30.110.10 70 165 7.5E-29 T 18-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 SUPERFAMILY SSF54364 2 72 1.44E-24 T 18-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 ProSitePatterns PS00938 Initiation factor 3 signature. 52 65 - T 18-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 77 161 1.5E-28 T 18-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 163 9.6E-53 T 18-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TWT_164 03c641d0a4ca7678b312b50f392d1384 182 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 70 1.7E-27 T 18-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TWT_550 9b4825cda49c201191e93e30d02e8268 144 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 53 143 2.8E-45 T 18-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TWT_550 9b4825cda49c201191e93e30d02e8268 144 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 52 140 25.133 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 PRINTS PR00975 Ribosomal protein S19 family signature 84 103 1.4E-23 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 PRINTS PR00975 Ribosomal protein S19 family signature 104 116 1.4E-23 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 PRINTS PR00975 Ribosomal protein S19 family signature 116 131 1.4E-23 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 Pfam PF00203 Ribosomal protein S19 54 134 2.6E-35 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 PIRSF PIRSF002144 46 144 9.6E-30 T 18-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 Gene3D G3DSA:3.30.860.10 52 144 8.6E-38 T 18-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 SUPERFAMILY SSF54570 54 134 1.44E-33 T 18-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_550 9b4825cda49c201191e93e30d02e8268 144 ProSitePatterns PS00323 Ribosomal protein S19 signature. 104 128 - T 18-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_047 5003d87dd07c10ba24683950bbabda65 251 SMART SM00862 173 248 4.6E-24 T 18-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TWT_047 5003d87dd07c10ba24683950bbabda65 251 SUPERFAMILY SSF52172 25 205 2.7E-41 T 18-10-2018 IPR011006 CheY-like superfamily TWT_047 5003d87dd07c10ba24683950bbabda65 251 Gene3D G3DSA:1.10.10.10 153 251 1.0E-30 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_047 5003d87dd07c10ba24683950bbabda65 251 Gene3D G3DSA:3.40.50.2300 19 152 1.1E-37 T 18-10-2018 TWT_047 5003d87dd07c10ba24683950bbabda65 251 Pfam PF00486 Transcriptional regulatory protein, C terminal 175 248 3.3E-24 T 18-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TWT_047 5003d87dd07c10ba24683950bbabda65 251 Pfam PF00072 Response regulator receiver domain 30 139 9.2E-27 T 18-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TWT_047 5003d87dd07c10ba24683950bbabda65 251 SMART SM00448 28 139 1.8E-43 T 18-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 SUPERFAMILY SSF52540 396 690 6.29E-72 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 612 690 2.9E-24 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Gene3D G3DSA:3.40.50.300 399 610 8.6E-81 T 18-10-2018 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 3.6E-39 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 523 541 3.6E-39 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 556 570 3.6E-39 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 451 469 3.6E-39 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Gene3D G3DSA:3.40.50.300 194 394 3.8E-65 T 18-10-2018 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 SMART SM01086 612 701 2.8E-30 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Pfam PF07724 AAA domain (Cdc48 subfamily) 446 606 1.1E-46 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 479 497 - T 18-10-2018 IPR028299 ClpA/B, conserved site 2 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 SMART SM00382 51 194 1.2E-11 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_746 72082bf8175f3a411da6f5dd2888466d 705 SMART SM00382 447 613 5.0E-12 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_746 72082bf8175f3a411da6f5dd2888466d 705 SUPERFAMILY SSF52540 13 395 6.73E-89 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_746 72082bf8175f3a411da6f5dd2888466d 705 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 145 157 - T 18-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Gene3D G3DSA:3.40.50.300 5 193 8.5E-70 T 18-10-2018 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Gene3D G3DSA:1.10.8.60 612 703 5.1E-26 T 18-10-2018 TWT_746 72082bf8175f3a411da6f5dd2888466d 705 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 187 6.8E-14 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 SUPERFAMILY SSF50129 25 119 6.48E-33 T 18-10-2018 IPR011032 GroES-like superfamily TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 SMART SM00883 26 118 8.5E-51 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 Hamap MF_00580 10 kDa chaperonin [groS]. 26 119 24.98 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 PRINTS PR00297 10kDa chaperonin signature 27 42 4.3E-29 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 PRINTS PR00297 10kDa chaperonin signature 84 96 4.3E-29 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 PRINTS PR00297 10kDa chaperonin signature 49 70 4.3E-29 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 PRINTS PR00297 10kDa chaperonin signature 105 118 4.3E-29 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 Pfam PF00166 Chaperonin 10 Kd subunit 27 118 3.8E-33 T 18-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 Gene3D G3DSA:2.30.33.40 21 120 4.8E-38 T 18-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TWT_074 6eb6cb256f8f0a5db369bf721e414e47 120 ProSitePatterns PS00681 Chaperonins cpn10 signature. 27 51 - T 18-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TWT_744 a6ed8da9727a594aa3aff8403e57c301 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 268 3.5E-60 T 18-10-2018 TWT_744 a6ed8da9727a594aa3aff8403e57c301 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 261 3.2E-18 T 18-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TWT_744 a6ed8da9727a594aa3aff8403e57c301 269 Gene3D G3DSA:3.60.10.10 1 268 1.3E-61 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_744 a6ed8da9727a594aa3aff8403e57c301 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 268 5.0E-66 T 18-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TWT_744 a6ed8da9727a594aa3aff8403e57c301 269 SUPERFAMILY SSF56219 2 269 1.96E-64 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_530 94400140f3175f45047d5712a7b54ab8 124 PIRSF PIRSF002134 1 124 5.5E-42 T 18-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_530 94400140f3175f45047d5712a7b54ab8 124 SUPERFAMILY SSF46946 2 121 7.21E-44 T 18-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TWT_530 94400140f3175f45047d5712a7b54ab8 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.6E-49 T 18-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_530 94400140f3175f45047d5712a7b54ab8 124 Gene3D G3DSA:4.10.910.10 73 124 2.0E-23 T 18-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_530 94400140f3175f45047d5712a7b54ab8 124 Gene3D G3DSA:1.10.8.50 1 72 1.5E-27 T 18-10-2018 TWT_530 94400140f3175f45047d5712a7b54ab8 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 25.497 T 18-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_530 94400140f3175f45047d5712a7b54ab8 124 Pfam PF00416 Ribosomal protein S13/S18 3 108 4.3E-30 T 18-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_530 94400140f3175f45047d5712a7b54ab8 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 18-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF01751 Toprim domain 4 124 1.5E-26 T 18-10-2018 IPR006171 TOPRIM domain TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 SMART SM00436 115 203 3.5E-46 T 18-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Gene3D G3DSA:1.10.460.10 146 570 4.5E-155 T 18-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 173 191 6.1E-34 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 89 102 6.1E-34 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 312 321 6.1E-34 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 391 407 6.1E-34 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 493 507 6.1E-34 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Gene3D G3DSA:3.40.50.140 1 145 1.0E-52 T 18-10-2018 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Gene3D G3DSA:1.10.290.10 278 406 4.5E-155 T 18-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 307 321 - T 18-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 SUPERFAMILY SSF56712 1 571 9.55E-174 T 18-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF13368 Topoisomerase C-terminal repeat 605 645 2.1E-5 T 18-10-2018 IPR025589 Topoisomerase C-terminal repeat TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF13368 Topoisomerase C-terminal repeat 715 764 1.5E-14 T 18-10-2018 IPR025589 Topoisomerase C-terminal repeat TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF13368 Topoisomerase C-terminal repeat 654 708 1.5E-12 T 18-10-2018 IPR025589 Topoisomerase C-terminal repeat TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF13368 Topoisomerase C-terminal repeat 776 825 1.1E-15 T 18-10-2018 IPR025589 Topoisomerase C-terminal repeat TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 SMART SM00493 2 115 8.2E-29 T 18-10-2018 IPR006171 TOPRIM domain TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 SMART SM00437 270 530 4.5E-106 T 18-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Gene3D G3DSA:2.70.20.10 195 477 4.5E-155 T 18-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 4 617 1.6E-218 T 18-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Pfam PF01131 DNA topoisomerase 139 567 3.5E-116 T 18-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TWT_696 8ff9823dd2fc039ea35d3b020eaaf5fa 841 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 734 50.044 T 18-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TWT_050 0d02cf90fd138ec093e6c89802826393 378 Gene3D G3DSA:1.10.3660.10 196 301 8.6E-24 T 18-10-2018 TWT_050 0d02cf90fd138ec093e6c89802826393 378 SUPERFAMILY SSF48179 194 283 3.51E-22 T 18-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TWT_050 0d02cf90fd138ec093e6c89802826393 378 SUPERFAMILY SSF51735 3 137 6.02E-22 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_050 0d02cf90fd138ec093e6c89802826393 378 SUPERFAMILY SSF55021 312 373 8.59E-8 T 18-10-2018 TWT_050 0d02cf90fd138ec093e6c89802826393 378 Gene3D G3DSA:3.30.2130.10 311 373 2.6E-6 T 18-10-2018 TWT_050 0d02cf90fd138ec093e6c89802826393 378 Pfam PF02153 Prephenate dehydrogenase 19 139 5.9E-15 T 18-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TWT_050 0d02cf90fd138ec093e6c89802826393 378 Pfam PF02153 Prephenate dehydrogenase 161 282 2.4E-18 T 18-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TWT_050 0d02cf90fd138ec093e6c89802826393 378 Gene3D G3DSA:3.40.50.720 2 195 1.3E-30 T 18-10-2018 TWT_647 59d0c4c9b0a90f862f3d8cf8c1a20875 223 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 182 2.1E-48 T 18-10-2018 IPR001303 Class II aldolase/adducin N-terminal TWT_647 59d0c4c9b0a90f862f3d8cf8c1a20875 223 SMART SM01007 7 184 9.0E-68 T 18-10-2018 IPR001303 Class II aldolase/adducin N-terminal TWT_647 59d0c4c9b0a90f862f3d8cf8c1a20875 223 Gene3D G3DSA:3.40.225.10 1 214 3.5E-70 T 18-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TWT_647 59d0c4c9b0a90f862f3d8cf8c1a20875 223 SUPERFAMILY SSF53639 3 209 2.16E-64 T 18-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TWT_249 c242fb40f4a9a4c5804222fd639c89b9 536 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 125 298 3.2E-61 T 18-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TWT_249 c242fb40f4a9a4c5804222fd639c89b9 536 Gene3D G3DSA:1.20.810.10 11 459 6.3E-94 T 18-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 TWT_249 c242fb40f4a9a4c5804222fd639c89b9 536 SUPERFAMILY SSF81342 26 304 4.08E-63 T 18-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 SUPERFAMILY SSF51735 17 184 6.07E-20 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 Gene3D G3DSA:3.40.50.720 14 189 2.0E-35 T 18-10-2018 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 SUPERFAMILY SSF48179 187 268 3.06E-9 T 18-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 18 122 2.9E-9 T 18-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 Gene3D G3DSA:1.10.3730.10 190 290 6.2E-7 T 18-10-2018 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 187 289 1.9E-16 T 18-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 PIRSF PIRSF000193 16 292 4.4E-83 T 18-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TWT_752 710b3d86fe92c111177f30a3e0eb520f 296 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 17 289 16.425 T 18-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TWT_661 be8deb063f73f5628316f5e2a9e10ee0 207 Gene3D G3DSA:1.10.1200.120 5 114 5.0E-23 T 18-10-2018 IPR036019 Gated mechanosensitive channel TWT_661 be8deb063f73f5628316f5e2a9e10ee0 207 SUPERFAMILY SSF81330 15 109 2.75E-19 T 18-10-2018 IPR036019 Gated mechanosensitive channel TWT_661 be8deb063f73f5628316f5e2a9e10ee0 207 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 5 105 3.0E-23 T 18-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 8 471 41.444 T 18-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:1.10.240.10 229 335 3.3E-30 T 18-10-2018 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 10 468 5.1E-101 T 18-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 4.1E-23 T 18-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 168 183 4.1E-23 T 18-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 189 211 4.1E-23 T 18-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 222 234 4.1E-23 T 18-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:3.40.50.620 2 227 9.2E-79 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Pfam PF01479 S4 domain 408 438 1.3E-7 T 18-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Pfam PF00579 tRNA synthetases class I (W and Y) 36 326 6.3E-74 T 18-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 18-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 SUPERFAMILY SSF52374 8 327 5.06E-91 T 18-10-2018 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:3.10.290.10 383 471 8.0E-15 T 18-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TWT_169 f154ce5a438e6fd3ebaa295b03073115 471 SUPERFAMILY SSF55174 405 469 2.75E-11 T 18-10-2018 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-41 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.999 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 SUPERFAMILY SSF74731 2 116 1.14E-43 T 18-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 Gene3D G3DSA:1.10.1900.20 57 117 1.7E-25 T 18-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 Pfam PF00453 Ribosomal protein L20 3 109 1.5E-42 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 6.0E-21 T 18-10-2018 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 Gene3D G3DSA:1.10.720.90 2 56 1.1E-17 T 18-10-2018 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 PRINTS PR00062 Ribosomal protein L20 signature 42 71 9.1E-38 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 PRINTS PR00062 Ribosomal protein L20 signature 12 41 9.1E-38 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_166 abb7fae94af2da9599b6847d1258bed1 136 PRINTS PR00062 Ribosomal protein L20 signature 75 101 9.1E-38 T 18-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_387 9638b359a385ce8f7a7d00d323bc8d56 575 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 429 525 4.7E-30 T 18-10-2018 IPR019236 Domain of unknown function DUF2183 TWT_387 9638b359a385ce8f7a7d00d323bc8d56 575 Pfam PF09335 SNARE associated Golgi protein 41 159 3.0E-21 T 18-10-2018 IPR032816 SNARE associated Golgi protein TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 Pfam PF11566 PI31 proteasome regulator N-terminal 116 217 8.2E-4 T 18-10-2018 IPR021625 PI31 proteasome regulator, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 76 95 - T 18-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 SUPERFAMILY SSF51395 3 332 1.31E-84 T 18-10-2018 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 PIRSF PIRSF000164 11 335 8.0E-98 T 18-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 Pfam PF01180 Dihydroorotate dehydrogenase 41 332 7.5E-81 T 18-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 Gene3D G3DSA:3.20.20.70 1 335 1.5E-107 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 333 7.4E-97 T 18-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TWT_238 e765e82d8f71ec9571d92f80be7924aa 335 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 286 306 - T 18-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.227 T 18-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 SUPERFAMILY SSF46992 3 85 3.79E-24 T 18-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 Pfam PF01649 Ribosomal protein S20 2 83 1.2E-23 T 18-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 83 1.2E-20 T 18-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 Gene3D G3DSA:1.20.58.110 1 86 1.2E-24 T 18-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_276 1a2745bce7554fbc7a254ccdd04dd640 95 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 22 83 1.0E-27 T 18-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 170 267 2.6E-21 T 18-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 21 128 3.7E-29 T 18-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 21 128 2.0E-30 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 169 270 5.1E-25 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF55957 386 473 2.62E-13 T 18-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 437 473 2.9E-8 T 18-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 18 160 1.9E-40 T 18-10-2018 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 186 265 5.1E-30 T 18-10-2018 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 275 382 1.4E-17 T 18-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.30.310.50 389 475 1.9E-18 T 18-10-2018 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 266 385 2.5E-24 T 18-10-2018 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 184 203 1.9E-20 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 220 233 1.9E-20 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 249 264 1.9E-20 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 105 119 1.9E-20 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_127 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 280 381 1.2E-21 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 Gene3D G3DSA:2.60.40.2600 135 273 9.7E-40 T 18-10-2018 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 202 250 - T 18-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 Gene3D G3DSA:1.10.287.90 45 134 3.1E-11 T 18-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 SUPERFAMILY SSF49503 139 269 1.45E-38 T 18-10-2018 IPR008972 Cupredoxin TWT_243 00b518977f3e47b4ec777a14eac1f590 290 SUPERFAMILY SSF81464 50 128 5.72E-14 T 18-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 221 238 1.3E-8 T 18-10-2018 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 239 256 1.3E-8 T 18-10-2018 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 136 155 1.3E-8 T 18-10-2018 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 201 221 1.3E-8 T 18-10-2018 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 142 257 4.5E-17 T 18-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_243 00b518977f3e47b4ec777a14eac1f590 290 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 55 266 4.0E-46 T 18-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_034 033624a282ecfc1e1bc89cbc60d26dee 268 SMART SM00382 77 248 3.3E-8 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_034 033624a282ecfc1e1bc89cbc60d26dee 268 SUPERFAMILY SSF52540 53 256 1.17E-43 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_034 033624a282ecfc1e1bc89cbc60d26dee 268 Gene3D G3DSA:3.40.50.300 28 266 1.7E-42 T 18-10-2018 TWT_034 033624a282ecfc1e1bc89cbc60d26dee 268 Pfam PF00005 ABC transporter 68 199 1.6E-18 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_720 74bab24b4d0693b506d5ccd17d96c385 147 PRINTS PR01483 Fatty acid synthase signature 22 44 1.4E-6 T 18-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TWT_720 74bab24b4d0693b506d5ccd17d96c385 147 PRINTS PR01483 Fatty acid synthase signature 44 65 1.4E-6 T 18-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TWT_720 74bab24b4d0693b506d5ccd17d96c385 147 SUPERFAMILY SSF54637 9 92 2.34E-24 T 18-10-2018 IPR029069 HotDog domain superfamily TWT_720 74bab24b4d0693b506d5ccd17d96c385 147 Pfam PF01575 MaoC like domain 15 92 4.9E-21 T 18-10-2018 IPR002539 MaoC-like dehydratase domain TWT_720 74bab24b4d0693b506d5ccd17d96c385 147 Gene3D G3DSA:3.10.129.10 6 146 9.4E-31 T 18-10-2018 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 322 344 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 359 376 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 396 409 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 117 127 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 63 87 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 101 115 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 170 190 3.5E-69 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF52540 6 398 5.71E-73 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF81767 232 351 1.03E-39 T 18-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.90.1440.10 229 351 3.3E-163 T 18-10-2018 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 812 0.0 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.40.50.300 22 398 3.3E-163 T 18-10-2018 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:1.10.3060.10 617 827 1.5E-67 T 18-10-2018 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SMART SM00958 229 341 3.4E-56 T 18-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF07516 SecA Wing and Scaffold domain 613 823 5.3E-61 T 18-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF01043 SecA preprotein cross-linking domain 235 341 3.6E-33 T 18-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 826 19.215 T 18-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF52540 400 603 1.5E-53 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.40.50.300 400 615 2.4E-85 T 18-10-2018 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF81886 616 828 1.19E-64 T 18-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 ProSitePatterns PS01312 SecA family signature. 483 498 - T 18-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 SMART SM00957 6 385 5.1E-252 T 18-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TWT_130 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF07517 SecA DEAD-like domain 8 384 1.7E-117 T 18-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TWT_182 7e78352758059f67301a45f064089fd4 1291 SUPERFAMILY SSF143517 1134 1218 3.27E-25 T 18-10-2018 IPR037235 TRCF-like, C-terminal domain TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:3.40.50.11180 61 145 1.8E-6 T 18-10-2018 TWT_182 7e78352758059f67301a45f064089fd4 1291 SUPERFAMILY SSF52540 922 1127 3.77E-42 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:3.40.50.300 614 1127 1.3E-214 T 18-10-2018 TWT_182 7e78352758059f67301a45f064089fd4 1291 SMART SM01058 614 716 1.5E-33 T 18-10-2018 IPR003711 CarD-like/TRCF domain TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:3.40.50.300 682 921 1.3E-214 T 18-10-2018 TWT_182 7e78352758059f67301a45f064089fd4 1291 Pfam PF03461 TRCF domain 1141 1217 1.2E-22 T 18-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TWT_182 7e78352758059f67301a45f064089fd4 1291 SUPERFAMILY SSF52540 665 923 1.32E-55 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_182 7e78352758059f67301a45f064089fd4 1291 Pfam PF00271 Helicase conserved C-terminal domain 951 1049 4.8E-11 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:2.30.30.840 618 681 1.3E-214 T 18-10-2018 TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:3.30.2060.10 195 277 1.2E-22 T 18-10-2018 TWT_182 7e78352758059f67301a45f064089fd4 1291 Pfam PF02559 CarD-like/TRCF domain 615 715 9.1E-25 T 18-10-2018 IPR003711 CarD-like/TRCF domain TWT_182 7e78352758059f67301a45f064089fd4 1291 SUPERFAMILY SSF52540 62 272 1.46E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_182 7e78352758059f67301a45f064089fd4 1291 Gene3D G3DSA:3.90.1150.50 1136 1234 1.4E-24 T 18-10-2018 IPR037235 TRCF-like, C-terminal domain TWT_182 7e78352758059f67301a45f064089fd4 1291 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 72 1233 25.967 T 18-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TWT_182 7e78352758059f67301a45f064089fd4 1291 SMART SM00487 740 930 1.5E-31 T 18-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TWT_182 7e78352758059f67301a45f064089fd4 1291 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 560 1213 7.4E-269 T 18-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TWT_182 7e78352758059f67301a45f064089fd4 1291 SMART SM00490 966 1050 3.6E-13 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_182 7e78352758059f67301a45f064089fd4 1291 SMART SM00982 1140 1244 4.3E-29 T 18-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TWT_182 7e78352758059f67301a45f064089fd4 1291 SUPERFAMILY SSF141259 608 684 3.01E-13 T 18-10-2018 IPR036101 CarD-like/TRCF domain superfamily TWT_182 7e78352758059f67301a45f064089fd4 1291 Pfam PF00270 DEAD/DEAH box helicase 748 906 2.3E-16 T 18-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TWT_662 458ef135edd4bca2564cba92593b95b9 348 Gene3D G3DSA:3.40.50.1980 231 344 5.8E-28 T 18-10-2018 TWT_662 458ef135edd4bca2564cba92593b95b9 348 Gene3D G3DSA:3.40.50.1980 74 230 1.6E-43 T 18-10-2018 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 229 246 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 74 95 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 99 117 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 118 137 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 278 295 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00691 Adhesin B signature 255 273 5.6E-23 T 18-10-2018 IPR006129 Adhesin B GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 Pfam PF01297 Zinc-uptake complex component A periplasmic 77 342 8.4E-60 T 18-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TWT_662 458ef135edd4bca2564cba92593b95b9 348 SUPERFAMILY SSF53807 73 345 1.77E-66 T 18-10-2018 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 74 92 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 310 329 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 105 118 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 118 135 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 229 250 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_662 458ef135edd4bca2564cba92593b95b9 348 PRINTS PR00690 Adhesin family signature 282 300 1.5E-25 T 18-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 SUPERFAMILY SSF47323 632 850 2.99E-37 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Gene3D G3DSA:1.10.730.10 11 793 1.8E-186 T 18-10-2018 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Gene3D G3DSA:3.40.50.620 23 579 1.8E-186 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Pfam PF08264 Anticodon-binding domain of tRNA 675 808 7.0E-26 T 18-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 616 5.8E-91 T 18-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Hamap MF_02005 Valine--tRNA ligase [valS]. 3 839 27.478 T 18-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 PRINTS PR00986 Valyl-tRNA synthetase signature 379 392 1.1E-16 T 18-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 PRINTS PR00986 Valyl-tRNA synthetase signature 250 267 1.1E-16 T 18-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 PRINTS PR00986 Valyl-tRNA synthetase signature 499 520 1.1E-16 T 18-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 1.1E-16 T 18-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 PRINTS PR00986 Valyl-tRNA synthetase signature 530 548 1.1E-16 T 18-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 SUPERFAMILY SSF52374 2 619 1.38E-105 T 18-10-2018 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 Gene3D G3DSA:3.90.740.10 197 375 1.8E-186 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 SUPERFAMILY SSF50677 218 357 7.59E-30 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_478 b5e186b5f83bde90dbf0db6733c7ebfe 856 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 18-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_727 35a69c15916e9985249b429828e9fbf3 263 SUPERFAMILY SSF56784 1 263 2.6E-44 T 18-10-2018 IPR036412 HAD-like superfamily TWT_727 35a69c15916e9985249b429828e9fbf3 263 Gene3D G3DSA:3.30.1240.10 89 185 8.5E-42 T 18-10-2018 TWT_727 35a69c15916e9985249b429828e9fbf3 263 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 225 1.1E-18 T 18-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TWT_727 35a69c15916e9985249b429828e9fbf3 263 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 18-10-2018 TWT_727 35a69c15916e9985249b429828e9fbf3 263 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 260 1.4E-56 T 18-10-2018 TWT_727 35a69c15916e9985249b429828e9fbf3 263 Gene3D G3DSA:3.40.50.1000 5 259 8.5E-42 T 18-10-2018 IPR023214 HAD superfamily TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Pfam PF02142 MGS-like domain 19 132 1.7E-17 T 18-10-2018 IPR011607 Methylglyoxal synthase-like domain TWT_084 c4a4566917799d73abbb9dda57b38b82 542 SMART SM00798 139 477 5.7E-149 T 18-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 SUPERFAMILY SSF53927 230 542 1.4E-106 T 18-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.140.20 225 382 5.2E-51 T 18-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.140.20 418 542 6.4E-49 T 18-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 PIRSF PIRSF000414 1 542 2.8E-196 T 18-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 SMART SM00851 19 134 8.0E-36 T 18-10-2018 IPR011607 Methylglyoxal synthase-like domain TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 542 37.962 T 18-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.50.1380 1 200 1.9E-74 T 18-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TWT_084 c4a4566917799d73abbb9dda57b38b82 542 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 476 3.5E-99 T 18-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_084 c4a4566917799d73abbb9dda57b38b82 542 SUPERFAMILY SSF52335 7 196 7.78E-57 T 18-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-15 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.9E-15 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.9E-15 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.9E-15 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 1.9E-15 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.50.50.60 143 257 3.3E-77 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 SUPERFAMILY SSF51905 3 354 9.43E-34 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.50.50.60 4 319 3.3E-77 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 4.4E-35 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 394 409 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.6E-38 T 18-10-2018 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 442 7.8E-8 T 18-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 18-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.30.390.30 338 450 1.7E-14 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_629 6e60ee9b3b9e0b7112c0e3b0251d8253 452 SUPERFAMILY SSF55424 341 445 6.01E-14 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 426 440 2.8E-14 T 18-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 318 331 2.8E-14 T 18-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 332 345 2.8E-14 T 18-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 410 424 2.8E-14 T 18-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 SUPERFAMILY SSF56322 31 477 5.23E-109 T 18-10-2018 IPR005801 ADC synthase GO:0009058 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 Gene3D G3DSA:3.60.120.10 21 479 5.7E-112 T 18-10-2018 IPR005801 ADC synthase GO:0009058 TWT_386 9922463bba1e8950164ded4cb2dc8690 480 Pfam PF00425 chorismate binding enzyme 215 469 8.7E-82 T 18-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 ProSitePatterns PS01058 SAICAR synthetase signature 2. 209 217 - T 18-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 SUPERFAMILY SSF56104 12 305 9.81E-75 T 18-10-2018 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 305 20.455 T 18-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 Gene3D G3DSA:3.30.470.20 111 247 2.4E-43 T 18-10-2018 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 Pfam PF01259 SAICAR synthetase 20 268 9.9E-73 T 18-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 ProSitePatterns PS01057 SAICAR synthetase signature 1. 112 126 - T 18-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TWT_109 ec6eedc0bd9faa50d1faa48d69bac419 305 Gene3D G3DSA:3.30.200.20 7 110 2.6E-25 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 177 1.1E-19 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 495 511 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 277 290 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 513 530 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 116 130 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 429 443 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 533 545 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 581 597 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.8E-67 T 18-10-2018 TWT_005 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.30.230.10 225 406 3.5E-65 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_005 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.30.565.10 6 224 7.6E-85 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_005 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.40.50.670 407 649 1.3E-93 T 18-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_005 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF56719 403 644 8.37E-80 T 18-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_005 6da93c1444a53ee620edfee1385439ae 649 ProSitePatterns PS00177 DNA topoisomerase II signature. 431 439 - T 18-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_005 6da93c1444a53ee620edfee1385439ae 649 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 578 638 3.8E-26 T 18-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF54211 226 399 2.09E-52 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_005 6da93c1444a53ee620edfee1385439ae 649 Pfam PF00204 DNA gyrase B 226 399 4.5E-57 T 18-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_005 6da93c1444a53ee620edfee1385439ae 649 SMART SM00387 34 178 2.6E-22 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_005 6da93c1444a53ee620edfee1385439ae 649 Pfam PF01751 Toprim domain 428 536 3.2E-16 T 18-10-2018 IPR006171 TOPRIM domain TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 618 634 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 369 383 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 479 488 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 602 614 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 251 269 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 383 403 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 321 337 1.4E-60 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 SMART SM00433 38 642 0.0 T 18-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_005 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF55874 9 214 3.8E-69 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_005 6da93c1444a53ee620edfee1385439ae 649 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 649 83.381 T 18-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TWT_005 6da93c1444a53ee620edfee1385439ae 649 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 649 3.7E-279 T 18-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 232 250 6.8E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 215 230 6.8E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 206 6.8E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 167 187 6.8E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 SUPERFAMILY SSF52540 166 345 4.02E-47 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Gene3D G3DSA:2.70.210.12 6 163 3.5E-47 T 18-10-2018 IPR036726 GTP1/OBG domain superfamily TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 9 339 3.4E-120 T 18-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Pfam PF09269 Domain of unknown function (DUF1967) 370 432 3.0E-22 T 18-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Pfam PF01018 GTP1/OBG 10 162 1.8E-47 T 18-10-2018 IPR006169 GTP1/OBG domain TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 ProSitePatterns PS00905 GTP1/OBG family signature. 217 230 - T 18-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 SUPERFAMILY SSF82051 9 162 1.29E-44 T 18-10-2018 IPR036726 GTP1/OBG domain superfamily TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 369 433 2.8E-25 T 18-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 SUPERFAMILY SSF102741 369 434 6.93E-19 T 18-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Gene3D G3DSA:3.40.50.300 165 371 3.3E-48 T 18-10-2018 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Hamap MF_01454 GTPase Obg [obg]. 8 342 42.38 T 18-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Gene3D G3DSA:2.40.240.60 372 435 5.1E-21 T 18-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TWT_471 c83d9f006e6e0f9a0c374a1afe21a2b8 445 Pfam PF01926 50S ribosome-binding GTPase 166 292 1.8E-24 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 SUPERFAMILY SSF53271 31 187 1.9E-49 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 Gene3D G3DSA:3.40.50.2020 37 326 1.3E-106 T 18-10-2018 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 158 173 - T 18-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 Pfam PF14572 Phosphoribosyl synthetase-associated domain 236 338 6.7E-19 T 18-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 SMART SM01400 34 150 1.6E-63 T 18-10-2018 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 Gene3D G3DSA:3.40.50.2020 177 316 1.3E-106 T 18-10-2018 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 35 340 5.2E-105 T 18-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 34 150 7.1E-40 T 18-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TWT_187 c8fa5dc6c9abdd75bc68d0dc36da9873 348 SUPERFAMILY SSF53271 136 328 1.12E-39 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 SUPERFAMILY SSF47240 6 163 1.28E-33 T 18-10-2018 IPR009078 Ferritin-like superfamily TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 Gene3D G3DSA:1.20.1260.10 7 164 2.4E-34 T 18-10-2018 IPR012347 Ferritin-like TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 ProSitePatterns PS00818 Dps protein family signature 1. 47 63 - T 18-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 47 63 1.1E-8 T 18-10-2018 IPR002177 DNA-binding protein Dps TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 142 160 1.1E-8 T 18-10-2018 IPR002177 DNA-binding protein Dps TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 71 87 1.1E-8 T 18-10-2018 IPR002177 DNA-binding protein Dps TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 PIRSF PIRSF005900 8 167 2.8E-38 T 18-10-2018 IPR002177 DNA-binding protein Dps TWT_395 2b69abf943f5101f32c50ffa1d816c3f 167 Pfam PF00210 Ferritin-like domain 35 163 8.3E-12 T 18-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 SMART SM00363 147 207 2.8E-14 T 18-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 Pfam PF01479 S4 domain 147 194 2.3E-15 T 18-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 Gene3D G3DSA:3.10.290.10 146 245 5.1E-58 T 18-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 Gene3D G3DSA:1.10.1050.10 62 259 5.1E-58 T 18-10-2018 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 49 260 28.502 T 18-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 62 146 2.4E-21 T 18-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 ProSitePatterns PS00632 Ribosomal protein S4 signature. 145 169 - T 18-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 SMART SM01390 61 146 1.6E-30 T 18-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 SUPERFAMILY SSF55174 62 258 4.19E-52 T 18-10-2018 TWT_378 6cb79e4620471a9c3ffd4cd6286c8c4b 261 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 61 259 7.4E-59 T 18-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TWT_252 72b625adc5d31c0c818c9c06a5da520c 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 77 7.0E-16 T 18-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TWT_252 72b625adc5d31c0c818c9c06a5da520c 82 SUPERFAMILY SSF47336 3 79 7.33E-19 T 18-10-2018 IPR036736 ACP-like superfamily TWT_252 72b625adc5d31c0c818c9c06a5da520c 82 Gene3D G3DSA:1.10.1200.10 1 82 7.5E-22 T 18-10-2018 IPR036736 ACP-like superfamily TWT_252 72b625adc5d31c0c818c9c06a5da520c 82 Pfam PF00550 Phosphopantetheine attachment site 11 77 4.6E-12 T 18-10-2018 IPR009081 Phosphopantetheine binding ACP domain TWT_252 72b625adc5d31c0c818c9c06a5da520c 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 16.353 T 18-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SUPERFAMILY SSF55021 668 744 4.58E-12 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Pfam PF13291 ACT domain 669 744 7.4E-14 T 18-10-2018 IPR002912 ACT domain TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SUPERFAMILY SSF81301 213 375 9.32E-58 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Pfam PF04607 Region found in RelA / SpoT proteins 256 365 2.6E-35 T 18-10-2018 IPR007685 RelA/SpoT GO:0015969 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SMART SM00471 64 174 5.0E-7 T 18-10-2018 IPR003607 HD/PDEase domain TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SUPERFAMILY SSF81271 405 473 2.62E-18 T 18-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Gene3D G3DSA:3.10.20.30 408 481 2.9E-27 T 18-10-2018 IPR012675 Beta-grasp domain superfamily TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SUPERFAMILY SSF109604 27 211 1.1E-61 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Pfam PF13328 HD domain 49 196 3.1E-42 T 18-10-2018 IPR003607 HD/PDEase domain TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Gene3D G3DSA:3.30.70.260 669 745 7.4E-16 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 SMART SM00954 256 366 1.0E-63 T 18-10-2018 IPR007685 RelA/SpoT GO:0015969 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Gene3D G3DSA:1.10.3210.10 21 212 8.5E-69 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Gene3D G3DSA:3.30.460.10 214 345 1.5E-44 T 18-10-2018 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 49 744 8.9E-224 T 18-10-2018 IPR004811 RelA/SpoT family GO:0015969 TWT_275 fdfe8cb9b6de52d84387d509107a628e 745 Pfam PF02824 TGS domain 414 473 5.9E-20 T 18-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TWT_289 99c972143b9bb5eee135238c81baedd9 297 Gene3D G3DSA:3.90.1720.10 165 295 7.4E-37 T 18-10-2018 TWT_289 99c972143b9bb5eee135238c81baedd9 297 SUPERFAMILY SSF54001 179 288 1.47E-34 T 18-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TWT_289 99c972143b9bb5eee135238c81baedd9 297 Pfam PF00877 NlpC/P60 family 199 293 2.9E-21 T 18-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 PIRSF PIRSF005572 4 381 1.5E-67 T 18-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 Pfam PF00266 Aminotransferase class-V 267 368 8.4E-10 T 18-10-2018 IPR000192 Aminotransferase class V domain TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 Pfam PF00266 Aminotransferase class-V 6 238 7.1E-25 T 18-10-2018 IPR000192 Aminotransferase class V domain TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 Gene3D G3DSA:3.90.1150.10 6 368 1.5E-79 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 SUPERFAMILY SSF53383 5 378 5.3E-56 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_416 f2e0208a58a82f4eee20e4aaddf147b7 383 Gene3D G3DSA:3.40.640.10 16 260 1.5E-79 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_788 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:3.30.559.10 206 438 9.0E-74 T 18-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TWT_788 a52df30e2565622486800d645192d783 440 Pfam PF00364 Biotin-requiring enzyme 8 77 3.6E-15 T 18-10-2018 IPR000089 Biotin/lipoyl attachment TWT_788 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:2.40.50.100 4 81 2.0E-18 T 18-10-2018 TWT_788 a52df30e2565622486800d645192d783 440 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 212 438 5.2E-74 T 18-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TWT_788 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:4.10.320.10 162 205 6.5E-13 T 18-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TWT_788 a52df30e2565622486800d645192d783 440 Pfam PF02817 e3 binding domain 170 204 9.9E-12 T 18-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TWT_788 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF47005 167 207 3.01E-10 T 18-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TWT_788 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF52777 209 438 6.23E-71 T 18-10-2018 TWT_788 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF51230 4 89 1.2E-20 T 18-10-2018 IPR011053 Single hybrid motif TWT_732 b20fcf774b2caec20fffc515a6756071 321 SUPERFAMILY SSF53850 2 194 2.71E-53 T 18-10-2018 TWT_732 b20fcf774b2caec20fffc515a6756071 321 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 262 1.6E-7 T 18-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 SUPERFAMILY SSF54782 211 319 2.75E-10 T 18-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 PIRSF PIRSF001438 1 321 6.5E-85 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 Gene3D G3DSA:3.40.190.10 88 186 9.6E-61 T 18-10-2018 TWT_732 b20fcf774b2caec20fffc515a6756071 321 PRINTS PR00151 Porphobilinogen deaminase signature 220 237 6.3E-22 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 PRINTS PR00151 Porphobilinogen deaminase signature 64 83 6.3E-22 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 PRINTS PR00151 Porphobilinogen deaminase signature 131 148 6.3E-22 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 PRINTS PR00151 Porphobilinogen deaminase signature 112 129 6.3E-22 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 193 3.3E-50 T 18-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 Gene3D G3DSA:3.40.190.10 5 193 9.6E-61 T 18-10-2018 TWT_732 b20fcf774b2caec20fffc515a6756071 321 Gene3D G3DSA:3.30.160.40 212 321 6.3E-11 T 18-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 302 6.0E-95 T 18-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_732 b20fcf774b2caec20fffc515a6756071 321 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 221 237 - T 18-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_403 f5b5e1061dbb97e8f0860773b36c993b 148 Gene3D G3DSA:2.40.50.140 2 117 3.5E-28 T 18-10-2018 TWT_403 f5b5e1061dbb97e8f0860773b36c993b 148 PIRSF PIRSF002070 2 148 1.9E-30 T 18-10-2018 TWT_403 f5b5e1061dbb97e8f0860773b36c993b 148 Hamap MF_00984 Single-stranded DNA-binding protein. 6 111 23.857 T 18-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TWT_403 f5b5e1061dbb97e8f0860773b36c993b 148 Pfam PF00436 Single-strand binding protein family 6 103 5.8E-17 T 18-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TWT_403 f5b5e1061dbb97e8f0860773b36c993b 148 SUPERFAMILY SSF50249 6 117 6.85E-25 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 30 257 1.8E-53 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 Gene3D G3DSA:3.40.1180.10 14 258 2.3E-73 T 18-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 SUPERFAMILY SSF64005 25 252 5.62E-63 T 18-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 37 257 4.1E-61 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 203 220 - T 18-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TWT_331 16d1c493b70e55fe97f704f8a3694b66 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 30 258 32.999 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 168 1.8E-21 T 18-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 173 15.171 T 18-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 Pfam PF01782 RimM N-terminal domain 5 95 2.1E-9 T 18-10-2018 IPR002676 RimM, N-terminal GO:0006364 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 Gene3D G3DSA:2.30.30.240 106 169 1.8E-5 T 18-10-2018 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 SUPERFAMILY SSF50346 106 172 1.15E-10 T 18-10-2018 IPR011033 PRC-barrel-like superfamily TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 Gene3D G3DSA:2.40.30.60 2 98 1.3E-7 T 18-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 TWT_459 8ac22baa8542c41e7e26690b74aec6db 182 SUPERFAMILY SSF50447 3 94 5.3E-7 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 Gene3D G3DSA:3.40.50.2300 34 165 9.1E-31 T 18-10-2018 TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 SMART SM00448 39 148 9.0E-30 T 18-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 Pfam PF00072 Response regulator receiver domain 42 148 3.0E-25 T 18-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 Gene3D G3DSA:1.10.10.10 167 225 6.2E-21 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 PIRSF PIRSF036382 29 225 3.5E-75 T 18-10-2018 IPR008327 Signal transduction response regulator, antiterminator TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 Pfam PF03861 ANTAR domain 168 219 3.2E-16 T 18-10-2018 IPR005561 ANTAR domain GO:0003723 TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 SUPERFAMILY SSF52172 41 219 5.83E-47 T 18-10-2018 IPR011006 CheY-like superfamily TWT_291 e4039a0d4585dfaa3a993af7cb07a71a 225 SMART SM01012 164 219 1.5E-19 T 18-10-2018 IPR005561 ANTAR domain GO:0003723 TWT_807 e1c969c8cd5a6480008bbfa37d5e9203 112 Pfam PF00825 Ribonuclease P 5 108 2.3E-20 T 18-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TWT_807 e1c969c8cd5a6480008bbfa37d5e9203 112 SUPERFAMILY SSF54211 4 109 4.3E-20 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_807 e1c969c8cd5a6480008bbfa37d5e9203 112 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 108 9.6E-15 T 18-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TWT_807 e1c969c8cd5a6480008bbfa37d5e9203 112 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 48 62 - T 18-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 TWT_807 e1c969c8cd5a6480008bbfa37d5e9203 112 Gene3D G3DSA:3.30.230.10 3 111 1.4E-20 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_094 a6f9c00035874ab45fb76c1e34512329 239 Pfam PF00005 ABC transporter 22 160 5.8E-18 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_094 a6f9c00035874ab45fb76c1e34512329 239 SUPERFAMILY SSF52540 3 212 3.85E-41 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_094 a6f9c00035874ab45fb76c1e34512329 239 Gene3D G3DSA:3.40.50.300 1 230 2.7E-42 T 18-10-2018 TWT_094 a6f9c00035874ab45fb76c1e34512329 239 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 185 191 - T 18-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 Gene3D G3DSA:3.30.360.10 185 475 8.8E-161 T 18-10-2018 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 SUPERFAMILY SSF55347 185 485 8.83E-105 T 18-10-2018 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 16 486 6.5E-167 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PIRSF PIRSF000110 4 487 2.8E-157 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 14 486 72.727 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 SUPERFAMILY SSF51735 13 198 3.74E-51 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 19 195 5.1E-49 T 18-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 151 164 3.0E-44 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 175 203 3.0E-44 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 227 244 3.0E-44 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 245 261 3.0E-44 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 335 361 3.0E-44 T 18-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 Gene3D G3DSA:3.40.50.720 19 434 8.8E-161 T 18-10-2018 TWT_343 69ac1d00898cdfccc4c16081e15e8702 487 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 198 485 2.1E-103 T 18-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TWT_206 3634e44a84c3bb2b38ad9bc888983ec0 114 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 40 106 1.0E-31 T 18-10-2018 TWT_206 3634e44a84c3bb2b38ad9bc888983ec0 114 SUPERFAMILY SSF55021 39 109 9.92E-15 T 18-10-2018 TWT_206 3634e44a84c3bb2b38ad9bc888983ec0 114 Pfam PF01842 ACT domain 40 103 1.6E-13 T 18-10-2018 IPR002912 ACT domain TWT_206 3634e44a84c3bb2b38ad9bc888983ec0 114 Gene3D G3DSA:3.30.70.260 37 111 1.6E-20 T 18-10-2018 TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 PIRSF PIRSF002756 4 353 5.0E-119 T 18-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 Gene3D G3DSA:3.40.190.10 117 291 7.3E-92 T 18-10-2018 TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 Gene3D G3DSA:3.40.190.10 39 337 7.3E-92 T 18-10-2018 TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 SUPERFAMILY SSF53850 35 351 1.18E-73 T 18-10-2018 TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 Pfam PF12849 PBP superfamily domain 28 320 1.5E-50 T 18-10-2018 IPR024370 PBP domain TWT_355 2fec2a9031b32122553e2af1cdadfff5 356 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 37 350 1.6E-66 T 18-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 SUPERFAMILY SSF56042 244 470 8.52E-48 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 SUPERFAMILY SSF55326 58 238 7.18E-46 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Pfam PF02769 AIR synthase related protein, C-terminal domain 648 754 6.8E-11 T 18-10-2018 IPR010918 PurM-like, C-terminal domain TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Pfam PF02769 AIR synthase related protein, C-terminal domain 246 400 4.4E-30 T 18-10-2018 IPR010918 PurM-like, C-terminal domain TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Pfam PF00586 AIR synthase related protein, N-terminal domain 131 233 2.6E-23 T 18-10-2018 IPR016188 PurM-like, N-terminal domain TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Pfam PF00586 AIR synthase related protein, N-terminal domain 484 601 1.8E-24 T 18-10-2018 IPR016188 PurM-like, N-terminal domain TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Gene3D G3DSA:3.30.1330.10 431 603 1.5E-56 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 780 266.097 T 18-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 SUPERFAMILY SSF55326 443 609 3.4E-53 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Gene3D G3DSA:3.90.650.10 609 777 1.0E-30 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 SUPERFAMILY SSF56042 612 777 1.64E-29 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Gene3D G3DSA:3.30.1330.10 84 237 2.2E-123 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 58 771 3.5E-242 T 18-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 PIRSF PIRSF001587 38 780 4.3E-305 T 18-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_794 e8c9149d9036344ab243ffdc75dc36b0 780 Gene3D G3DSA:3.90.650.10 70 409 2.2E-123 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_586 d043106507073c6e338c1fd1e7522351 766 Gene3D G3DSA:3.30.1130.10 348 456 2.7E-23 T 18-10-2018 TWT_586 d043106507073c6e338c1fd1e7522351 766 Pfam PF00809 Pterin binding enzyme 17 273 2.1E-77 T 18-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_586 d043106507073c6e338c1fd1e7522351 766 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 18-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_586 d043106507073c6e338c1fd1e7522351 766 SUPERFAMILY SSF51717 14 287 4.71E-86 T 18-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_586 d043106507073c6e338c1fd1e7522351 766 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 18-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_586 d043106507073c6e338c1fd1e7522351 766 Gene3D G3DSA:3.20.20.20 3 292 1.2E-95 T 18-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_586 d043106507073c6e338c1fd1e7522351 766 Gene3D G3DSA:3.30.70.560 493 589 2.3E-16 T 18-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 Gene3D G3DSA:3.30.70.560 624 702 2.8E-13 T 18-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 286 2.3E-84 T 18-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TWT_586 d043106507073c6e338c1fd1e7522351 766 TIGRFAM TIGR00526 folB_dom: FolB domain 349 447 2.2E-17 T 18-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TWT_586 d043106507073c6e338c1fd1e7522351 766 Pfam PF02152 Dihydroneopterin aldolase 350 446 2.8E-22 T 18-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TWT_586 d043106507073c6e338c1fd1e7522351 766 SUPERFAMILY SSF55083 635 698 5.62E-14 T 18-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 SUPERFAMILY SSF55083 494 584 5.62E-15 T 18-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 634 678 1.6E-7 T 18-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 497 585 2.9E-11 T 18-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TWT_586 d043106507073c6e338c1fd1e7522351 766 SMART SM00905 350 451 1.1E-26 T 18-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TWT_586 d043106507073c6e338c1fd1e7522351 766 SUPERFAMILY SSF55620 349 447 3.0E-23 T 18-10-2018 TWT_476 f95a9d08542cd633481db3f0b3994244 461 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 456 4.9E-84 T 18-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 Gene3D G3DSA:3.40.1190.10 1 304 1.8E-79 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 Gene3D G3DSA:3.90.190.20 307 460 2.7E-22 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 18-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 Pfam PF08245 Mur ligase middle domain 43 284 3.8E-15 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_476 f95a9d08542cd633481db3f0b3994244 461 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 41 64 - T 18-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 357 4.0E-7 T 18-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TWT_476 f95a9d08542cd633481db3f0b3994244 461 PIRSF PIRSF001563 387 460 2.2 T 18-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 PIRSF PIRSF001563 4 391 8.6E-90 T 18-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 SUPERFAMILY SSF53244 307 457 3.85E-18 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_476 f95a9d08542cd633481db3f0b3994244 461 SUPERFAMILY SSF53623 3 303 9.55E-75 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Pfam PF04545 Sigma-70, region 4 322 375 2.8E-15 T 18-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 387 29.916 T 18-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 SUPERFAMILY SSF88946 86 224 4.45E-53 T 18-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 150 375 6.2E-34 T 18-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 PRINTS PR00046 Major sigma-70 factor signature 202 210 5.5E-28 T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 PRINTS PR00046 Major sigma-70 factor signature 326 338 5.5E-28 T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 PRINTS PR00046 Major sigma-70 factor signature 362 373 5.5E-28 T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 PRINTS PR00046 Major sigma-70 factor signature 178 191 5.5E-28 T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 PRINTS PR00046 Major sigma-70 factor signature 347 362 5.5E-28 T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Pfam PF00140 Sigma-70 factor, region 1.2 89 122 6.0E-16 T 18-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 SUPERFAMILY SSF88659 227 300 1.1E-19 T 18-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 178 191 - T 18-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 150 386 5.4E-109 T 18-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Pfam PF04539 Sigma-70 region 3 233 309 2.5E-27 T 18-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Pfam PF04542 Sigma-70 region 2 154 223 2.3E-21 T 18-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 SUPERFAMILY SSF88659 284 386 7.85E-25 T 18-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Gene3D G3DSA:1.10.601.10 87 124 3.2E-9 T 18-10-2018 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Gene3D G3DSA:1.10.601.10 125 226 2.9E-51 T 18-10-2018 TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Gene3D G3DSA:1.10.10.10 304 387 5.5E-29 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_499 20d865a0e922d0fdd1de7b3cbe53c307 387 Gene3D G3DSA:1.10.10.10 227 301 4.4E-28 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_223 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF53244 316 453 1.52E-23 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_223 68c0af630229d4a361031553d077f61f 464 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 453 1.8E-94 T 18-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_223 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF53623 107 313 2.09E-46 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_223 68c0af630229d4a361031553d077f61f 464 Pfam PF08245 Mur ligase middle domain 112 293 3.1E-37 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_223 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.40.1390.10 1 85 5.0E-18 T 18-10-2018 TWT_223 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF63418 29 98 7.19E-18 T 18-10-2018 IPR035911 MurE/MurF, N-terminal TWT_223 68c0af630229d4a361031553d077f61f 464 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 393 2.2E-5 T 18-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TWT_223 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.40.1190.10 87 312 4.6E-55 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_223 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.90.190.20 315 463 4.6E-24 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_223 68c0af630229d4a361031553d077f61f 464 Pfam PF01225 Mur ligase family, catalytic domain 32 84 1.0E-7 T 18-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TWT_223 68c0af630229d4a361031553d077f61f 464 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 456 27.953 T 18-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_501 fc821732437e95185b7441afefacb096 522 SUPERFAMILY SSF53187 188 510 2.73E-102 T 18-10-2018 TWT_501 fc821732437e95185b7441afefacb096 522 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 193 507 2.5E-106 T 18-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 PRINTS PR00481 Cytosol aminopeptidase signature 328 349 1.9E-48 T 18-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 1.9E-48 T 18-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 PRINTS PR00481 Cytosol aminopeptidase signature 350 370 1.9E-48 T 18-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 PRINTS PR00481 Cytosol aminopeptidase signature 378 393 1.9E-48 T 18-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 PRINTS PR00481 Cytosol aminopeptidase signature 269 286 1.9E-48 T 18-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 13 515 30.422 T 18-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 Gene3D G3DSA:3.40.220.10 19 167 1.9E-17 T 18-10-2018 TWT_501 fc821732437e95185b7441afefacb096 522 SUPERFAMILY SSF52949 41 165 4.65E-17 T 18-10-2018 TWT_501 fc821732437e95185b7441afefacb096 522 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 354 361 - T 18-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TWT_501 fc821732437e95185b7441afefacb096 522 Gene3D G3DSA:3.40.630.10 173 515 9.8E-115 T 18-10-2018 TWT_501 fc821732437e95185b7441afefacb096 522 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 58 156 4.3E-12 T 18-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 SMART SM00240 188 238 2.6E-10 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 Pfam PF00498 FHA domain 189 252 3.4E-16 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 Gene3D G3DSA:2.60.200.20 167 260 1.9E-22 T 18-10-2018 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 Gene3D G3DSA:3.30.2320.60 43 166 1.1E-21 T 18-10-2018 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 Pfam PF12401 Protein of unknown function (DUF2662) 50 160 4.4E-25 T 18-10-2018 IPR022128 Domain of unknown function DUF3662 TWT_772 73cc83269f1ff89296ad51c087b3365d 265 SUPERFAMILY SSF49879 178 260 9.56E-22 T 18-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TWT_137 531cd23eaee9009947efe5012fac90cd 533 PIRSF PIRSF002741 26 532 1.3E-55 T 18-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TWT_137 531cd23eaee9009947efe5012fac90cd 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 455 9.3E-44 T 18-10-2018 IPR000914 Solute-binding protein family 5 domain TWT_137 531cd23eaee9009947efe5012fac90cd 533 Gene3D G3DSA:3.10.105.10 285 506 2.8E-88 T 18-10-2018 TWT_137 531cd23eaee9009947efe5012fac90cd 533 SUPERFAMILY SSF53850 28 529 1.09E-81 T 18-10-2018 TWT_137 531cd23eaee9009947efe5012fac90cd 533 Gene3D G3DSA:3.40.190.10 47 519 2.8E-88 T 18-10-2018 TWT_137 531cd23eaee9009947efe5012fac90cd 533 Gene3D G3DSA:3.90.76.10 66 184 2.8E-88 T 18-10-2018 TWT_292 83c3e24479085649a936e8c32d997d5d 356 SMART SM00279 181 216 1.9E-11 T 18-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TWT_292 83c3e24479085649a936e8c32d997d5d 356 Gene3D G3DSA:3.40.50.1010 11 285 4.8E-80 T 18-10-2018 TWT_292 83c3e24479085649a936e8c32d997d5d 356 SMART SM00475 9 269 2.4E-92 T 18-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TWT_292 83c3e24479085649a936e8c32d997d5d 356 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 269 1.3E-21 T 18-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TWT_292 83c3e24479085649a936e8c32d997d5d 356 SUPERFAMILY SSF88723 9 178 1.49E-45 T 18-10-2018 IPR029060 PIN-like domain superfamily TWT_292 83c3e24479085649a936e8c32d997d5d 356 SUPERFAMILY SSF47807 179 292 1.5E-25 T 18-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TWT_292 83c3e24479085649a936e8c32d997d5d 356 Gene3D G3DSA:1.10.150.20 182 254 4.8E-80 T 18-10-2018 TWT_292 83c3e24479085649a936e8c32d997d5d 356 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 10 178 3.6E-47 T 18-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TWT_154 5be287a425b8fb706d50f16744f05ff8 164 Gene3D G3DSA:3.90.80.10 2 164 1.4E-62 T 18-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_154 5be287a425b8fb706d50f16744f05ff8 164 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 7 164 34.527 T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_154 5be287a425b8fb706d50f16744f05ff8 164 Pfam PF00719 Inorganic pyrophosphatase 11 162 8.3E-57 T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_154 5be287a425b8fb706d50f16744f05ff8 164 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 58 64 - T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_154 5be287a425b8fb706d50f16744f05ff8 164 SUPERFAMILY SSF50324 7 163 5.76E-62 T 18-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_307 5be287a425b8fb706d50f16744f05ff8 164 Gene3D G3DSA:3.90.80.10 2 164 1.4E-62 T 18-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_307 5be287a425b8fb706d50f16744f05ff8 164 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 7 164 34.527 T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_307 5be287a425b8fb706d50f16744f05ff8 164 Pfam PF00719 Inorganic pyrophosphatase 11 162 8.3E-57 T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_307 5be287a425b8fb706d50f16744f05ff8 164 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 58 64 - T 18-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_307 5be287a425b8fb706d50f16744f05ff8 164 SUPERFAMILY SSF50324 7 163 5.76E-62 T 18-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TWT_244 31a9d86f35ce28068f609759a4282760 543 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 23 528 9.6E-210 T 18-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TWT_244 31a9d86f35ce28068f609759a4282760 543 Gene3D G3DSA:1.20.210.10 7 536 4.3E-201 T 18-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 252 306 - T 18-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 139 151 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 21 46 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 296 311 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 171 189 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 219 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 69 92 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 381 400 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 250 271 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 120 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 353 371 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 229 250 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 339 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 431 452 3.2E-105 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 SUPERFAMILY SSF81442 20 530 1.02E-172 T 18-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_244 31a9d86f35ce28068f609759a4282760 543 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 31 475 8.4E-148 T 18-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_557 847c186c9b0b4c524c6a1672d342be56 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_557 847c186c9b0b4c524c6a1672d342be56 233 Pfam PF00005 ABC transporter 18 161 3.5E-31 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_557 847c186c9b0b4c524c6a1672d342be56 233 SMART SM00382 26 210 2.7E-11 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_557 847c186c9b0b4c524c6a1672d342be56 233 PIRSF PIRSF039137 1 233 1.1E-105 T 18-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TWT_557 847c186c9b0b4c524c6a1672d342be56 233 SUPERFAMILY SSF52540 2 231 5.01E-59 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_557 847c186c9b0b4c524c6a1672d342be56 233 Gene3D G3DSA:3.40.50.300 1 233 8.0E-65 T 18-10-2018 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 93 145 9.0E-24 T 18-10-2018 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 PIRSF PIRSF016262 17 233 2.8E-57 T 18-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 89 104 - T 18-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 Pfam PF03099 Biotin/lipoate A/B protein ligase family 80 178 2.0E-9 T 18-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 Hamap MF_00013 Octanoyltransferase [lipB]. 18 228 32.375 T 18-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 Gene3D G3DSA:3.30.930.10 16 226 1.5E-65 T 18-10-2018 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 49 217 1.1E-41 T 18-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TWT_463 7cb21b94c158223b648aabd19b35bd30 235 SUPERFAMILY SSF55681 13 227 6.3E-56 T 18-10-2018 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 46 63 - T 18-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 SUPERFAMILY SSF51430 12 273 3.01E-82 T 18-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PIRSF PIRSF000097 7 276 5.4E-79 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 Pfam PF00248 Aldo/keto reductase family 26 266 2.0E-45 T 18-10-2018 IPR023210 NADP-dependent oxidoreductase domain TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 18-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PRINTS PR00069 Aldo-keto reductase signature 162 191 5.1E-47 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PRINTS PR00069 Aldo-keto reductase signature 42 66 5.1E-47 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PRINTS PR00069 Aldo-keto reductase signature 96 114 5.1E-47 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PRINTS PR00069 Aldo-keto reductase signature 128 145 5.1E-47 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 PRINTS PR00069 Aldo-keto reductase signature 201 225 5.1E-47 T 18-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TWT_016 da3e74b064c58ef8d51e4c2b9c87b600 283 Gene3D G3DSA:3.20.20.100 8 276 3.8E-101 T 18-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TWT_197 ac8b8e83e5fa15d83f20d2d6d994d24d 390 Gene3D G3DSA:1.20.1250.20 205 386 6.3E-13 T 18-10-2018 TWT_197 ac8b8e83e5fa15d83f20d2d6d994d24d 390 Gene3D G3DSA:1.20.1250.20 1 184 3.1E-20 T 18-10-2018 TWT_197 ac8b8e83e5fa15d83f20d2d6d994d24d 390 Pfam PF07690 Major Facilitator Superfamily 6 345 6.8E-32 T 18-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TWT_197 ac8b8e83e5fa15d83f20d2d6d994d24d 390 SUPERFAMILY SSF103473 3 380 8.24E-44 T 18-10-2018 IPR036259 MFS transporter superfamily TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 19 182 2.1E-71 T 18-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 188 331 3.5E-60 T 18-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 SUPERFAMILY SSF48179 188 331 7.14E-63 T 18-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 Gene3D G3DSA:1.10.3730.40 187 333 5.6E-64 T 18-10-2018 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 Gene3D G3DSA:3.40.50.720 1 186 3.8E-71 T 18-10-2018 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 6 333 42.415 T 18-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 20 333 6.4E-122 T 18-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 SUPERFAMILY SSF51735 7 187 1.32E-65 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 PIRSF PIRSF000116 207 331 4.3E-15 T 18-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_207 07c74aa0f319bb613a12b8cf44dc3798 333 PIRSF PIRSF000116 8 213 4.3E-39 T 18-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TWT_302 3d20097a2e19ee02129ffd320e41a6b4 293 Pfam PF00121 Triosephosphate isomerase 20 288 1.9E-45 T 18-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_302 3d20097a2e19ee02129ffd320e41a6b4 293 ProSitePatterns PS00171 Triosephosphate isomerase active site. 216 226 - T 18-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_302 3d20097a2e19ee02129ffd320e41a6b4 293 Gene3D G3DSA:3.20.20.70 16 292 7.0E-67 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_302 3d20097a2e19ee02129ffd320e41a6b4 293 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 18 290 46.071 T 18-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_302 3d20097a2e19ee02129ffd320e41a6b4 293 SUPERFAMILY SSF51351 19 290 6.81E-54 T 18-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 Gene3D G3DSA:3.40.50.880 285 535 5.9E-95 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 Hamap MF_01227 CTP synthase [pyrG]. 4 532 46.993 T 18-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 Gene3D G3DSA:3.40.50.300 1 284 1.6E-122 T 18-10-2018 TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 SUPERFAMILY SSF52540 4 267 5.67E-113 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 Pfam PF00117 Glutamine amidotransferase class-I 300 526 5.6E-48 T 18-10-2018 IPR017926 Glutamine amidotransferase TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 Pfam PF06418 CTP synthase N-terminus 5 265 1.3E-116 T 18-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 TIGRFAM TIGR00337 PyrG: CTP synthase 4 527 3.0E-219 T 18-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TWT_100 7e39af68aefdad30ec6d4cb82161c913 545 SUPERFAMILY SSF52317 288 532 9.49E-70 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_371 a41f440d46663d135a22007aff4c2574 169 PRINTS PR01100 Shikimate kinase family signature 6 21 4.0E-9 T 18-10-2018 TWT_371 a41f440d46663d135a22007aff4c2574 169 PRINTS PR01100 Shikimate kinase family signature 30 43 4.0E-9 T 18-10-2018 TWT_371 a41f440d46663d135a22007aff4c2574 169 PRINTS PR01100 Shikimate kinase family signature 93 110 4.0E-9 T 18-10-2018 TWT_371 a41f440d46663d135a22007aff4c2574 169 PRINTS PR01100 Shikimate kinase family signature 73 82 4.0E-9 T 18-10-2018 TWT_371 a41f440d46663d135a22007aff4c2574 169 Gene3D G3DSA:3.40.50.300 4 167 4.6E-30 T 18-10-2018 TWT_371 a41f440d46663d135a22007aff4c2574 169 SUPERFAMILY SSF52540 4 159 9.09E-17 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_371 a41f440d46663d135a22007aff4c2574 169 Hamap MF_00109 Shikimate kinase [aroK]. 3 161 16.73 T 18-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TWT_371 a41f440d46663d135a22007aff4c2574 169 Pfam PF01202 Shikimate kinase 13 160 2.4E-27 T 18-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TWT_492 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:1.20.5.320 436 470 3.2E-16 T 18-10-2018 TWT_492 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:3.40.50.720 2 178 1.1E-50 T 18-10-2018 TWT_492 2497f2017911400c86d31334b9203e83 476 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 468 3.3E-184 T 18-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PIRSF PIRSF000109 1 475 9.2E-183 T 18-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 177 467 4.3E-113 T 18-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 SMART SM01350 177 468 6.4E-178 T 18-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:1.10.1040.10 179 435 3.3E-92 T 18-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TWT_492 2497f2017911400c86d31334b9203e83 476 SUPERFAMILY SSF48179 175 469 1.21E-108 T 18-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TWT_492 2497f2017911400c86d31334b9203e83 476 SUPERFAMILY SSF51735 3 175 5.04E-46 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_492 2497f2017911400c86d31334b9203e83 476 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 170 7.5E-46 T 18-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 118 143 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 65 94 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 166 194 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_492 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 1.4E-75 T 18-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.3E-55 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 PIRSF PIRSF002133 1 124 1.1E-53 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 1.1E-64 T 18-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 SUPERFAMILY SSF50249 2 123 1.11E-51 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 Pfam PF00164 Ribosomal protein S12/S23 12 122 1.4E-41 T 18-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 Gene3D G3DSA:2.40.50.140 1 124 3.4E-61 T 18-10-2018 TWT_677 d3bc3dd6d5e35ea748aba66f13b50723 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.783 T 18-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 SUPERFAMILY SSF54631 272 399 3.28E-24 T 18-10-2018 TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 Gene3D G3DSA:1.25.60.10 167 268 2.6E-20 T 18-10-2018 IPR038076 MgtE, N-terminal domain superfamily TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 SMART SM00924 170 273 2.6E-28 T 18-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 SMART SM00116 280 338 9.2 T 18-10-2018 IPR000644 CBS domain TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 SMART SM00116 349 397 1.7E-4 T 18-10-2018 IPR000644 CBS domain TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 Gene3D G3DSA:3.10.580.10 270 399 5.5E-32 T 18-10-2018 TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 Pfam PF00571 CBS domain 345 397 1.1E-6 T 18-10-2018 IPR000644 CBS domain TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 Pfam PF00571 CBS domain 274 335 8.0E-5 T 18-10-2018 IPR000644 CBS domain TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 SUPERFAMILY SSF158791 169 268 4.45E-23 T 18-10-2018 TWT_523 92fec8a173feaff8a1e16ce96ca1c7c2 421 Pfam PF03448 MgtE intracellular N domain 172 270 3.0E-23 T 18-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TWT_511 7e369b9ab3d87ca9f83135e9a2efdd3f 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 127 141 - T 18-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_511 7e369b9ab3d87ca9f83135e9a2efdd3f 303 Gene3D G3DSA:3.30.2350.10 77 299 4.4E-68 T 18-10-2018 TWT_511 7e369b9ab3d87ca9f83135e9a2efdd3f 303 Pfam PF00849 RNA pseudouridylate synthase 84 235 6.6E-29 T 18-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_511 7e369b9ab3d87ca9f83135e9a2efdd3f 303 SUPERFAMILY SSF55120 76 296 1.09E-67 T 18-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_511 7e369b9ab3d87ca9f83135e9a2efdd3f 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 72 296 8.2E-71 T 18-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_248 ad816323d1e459757f06be1467a097b3 327 Pfam PF00355 Rieske [2Fe-2S] domain 243 299 1.2E-10 T 18-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TWT_248 ad816323d1e459757f06be1467a097b3 327 Gene3D G3DSA:2.102.10.10 171 324 5.9E-40 T 18-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TWT_248 ad816323d1e459757f06be1467a097b3 327 SUPERFAMILY SSF50022 129 325 4.58E-30 T 18-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TWT_248 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 269 281 1.0E-5 T 18-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TWT_248 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 283 295 1.0E-5 T 18-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TWT_248 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 247 258 1.0E-5 T 18-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SUPERFAMILY SSF53254 179 282 3.33E-15 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Pfam PF00293 NUDIX domain 29 159 4.0E-11 T 18-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 18-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SUPERFAMILY SSF55811 14 170 1.22E-22 T 18-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 182 246 1.5E-6 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Gene3D G3DSA:3.40.50.1240 179 299 2.1E-16 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SMART SM00855 180 278 0.0042 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_660 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Gene3D G3DSA:3.90.79.10 16 173 1.3E-27 T 18-10-2018 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 43 506 7.1E-156 T 18-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 Gene3D G3DSA:3.90.1300.10 33 513 4.5E-158 T 18-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 Pfam PF01425 Amidase 54 493 1.5E-134 T 18-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 SUPERFAMILY SSF75304 35 510 1.44E-138 T 18-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 ProSitePatterns PS00571 Amidases signature. 182 213 - T 18-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TWT_412 0db744224bba2e4f4a5c8f80ddc49f90 524 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 41 508 74.502 T 18-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TWT_361 ebbac5ff1a417913326c8d036158a167 417 SUPERFAMILY SSF52507 8 182 2.49E-51 T 18-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TWT_361 ebbac5ff1a417913326c8d036158a167 417 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 401 1.2E-107 T 18-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TWT_361 ebbac5ff1a417913326c8d036158a167 417 SUPERFAMILY SSF102645 190 404 3.27E-61 T 18-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TWT_361 ebbac5ff1a417913326c8d036158a167 417 Pfam PF02441 Flavoprotein 8 181 3.7E-37 T 18-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TWT_361 ebbac5ff1a417913326c8d036158a167 417 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 191 377 6.7E-59 T 18-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TWT_361 ebbac5ff1a417913326c8d036158a167 417 Gene3D G3DSA:3.40.50.1950 6 187 6.4E-48 T 18-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TWT_361 ebbac5ff1a417913326c8d036158a167 417 Gene3D G3DSA:3.40.50.10300 188 407 5.1E-71 T 18-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 Pfam PF00588 SpoU rRNA Methylase family 114 259 2.5E-33 T 18-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 23 263 9.5E-51 T 18-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 Gene3D G3DSA:3.40.1280.10 94 263 5.2E-46 T 18-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 SUPERFAMILY SSF75217 87 263 6.02E-39 T 18-10-2018 IPR029028 Alpha/beta knot methyltransferases TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 26 98 2.8E-13 T 18-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 SUPERFAMILY SSF55315 24 95 2.0E-8 T 18-10-2018 IPR029064 50S ribosomal protein L30e-like TWT_346 6f65fcd674070ec1a2f5cd96da329089 263 SMART SM00967 25 99 9.1E-11 T 18-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TWT_356 6b0b51fab3467630bf1a436d453cc15c 364 SUPERFAMILY SSF53448 7 287 7.68E-52 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_356 6b0b51fab3467630bf1a436d453cc15c 364 Gene3D G3DSA:3.90.550.10 6 358 1.0E-98 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_356 6b0b51fab3467630bf1a436d453cc15c 364 Pfam PF00483 Nucleotidyl transferase 9 287 1.0E-45 T 18-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TWT_356 6b0b51fab3467630bf1a436d453cc15c 364 SUPERFAMILY SSF159283 303 356 4.05E-12 T 18-10-2018 TWT_356 6b0b51fab3467630bf1a436d453cc15c 364 Pfam PF01050 Mannose-6-phosphate isomerase 323 362 1.5E-5 T 18-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 SUPERFAMILY SSF52374 110 438 9.38E-72 T 18-10-2018 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 552 22.466 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 SUPERFAMILY SSF47323 422 552 1.05E-34 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 4 552 1.1E-102 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Gene3D G3DSA:1.10.730.10 423 552 1.5E-129 T 18-10-2018 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Pfam PF00750 tRNA synthetases class I (R) 96 389 2.0E-15 T 18-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Gene3D G3DSA:3.40.50.620 116 422 1.5E-129 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 SUPERFAMILY SSF55190 5 107 2.22E-15 T 18-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Pfam PF05746 DALR anticodon binding domain 428 552 6.7E-30 T 18-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 SMART SM01016 4 87 3.8E-18 T 18-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 116 131 1.3E-19 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 1.3E-19 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 155 168 1.3E-19 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 147 1.3E-19 T 18-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 5 87 1.6E-13 T 18-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 SMART SM00836 428 552 1.3E-43 T 18-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TWT_351 d2dcaa8cb2d867e40d475a189ee2466b 552 Gene3D G3DSA:3.30.1360.70 2 111 1.5E-17 T 18-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 312 751 9.9E-161 T 18-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 SUPERFAMILY SSF89550 7 283 1.59E-31 T 18-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Gene3D G3DSA:1.10.10.1600 445 531 1.4E-15 T 18-10-2018 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 SMART SM00481 8 75 1.3E-28 T 18-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TWT_510 ec038162ca77b1abae4a608acb067f80 1164 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 7 1040 0.0 T 18-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Gene3D G3DSA:3.20.20.140 2 289 1.5E-99 T 18-10-2018 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Pfam PF01336 OB-fold nucleic acid binding domain 1004 1080 2.7E-10 T 18-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Pfam PF02811 PHP domain 9 193 2.9E-49 T 18-10-2018 IPR004013 PHP domain GO:0003824 TWT_510 ec038162ca77b1abae4a608acb067f80 1164 Pfam PF14579 Helix-hairpin-helix motif 826 913 2.4E-23 T 18-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TWT_612 f09518f304ed8d067e6036e229dee2c7 201 Gene3D G3DSA:1.20.120.1760 1 143 6.8E-13 T 18-10-2018 TWT_612 f09518f304ed8d067e6036e229dee2c7 201 PIRSF PIRSF000847 1 201 1.4E-44 T 18-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TWT_612 f09518f304ed8d067e6036e229dee2c7 201 Pfam PF01066 CDP-alcohol phosphatidyltransferase 1 66 3.8E-17 T 18-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TWT_612 f09518f304ed8d067e6036e229dee2c7 201 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 196 8.6E-37 T 18-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TWT_612 f09518f304ed8d067e6036e229dee2c7 201 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 44 66 - T 18-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TWT_225 3bf0be10d52ada007361b34795281311 531 SUPERFAMILY SSF53623 135 364 1.06E-49 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_225 3bf0be10d52ada007361b34795281311 531 SUPERFAMILY SSF53244 371 525 1.02E-30 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_225 3bf0be10d52ada007361b34795281311 531 Gene3D G3DSA:3.90.190.20 373 529 2.9E-36 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_225 3bf0be10d52ada007361b34795281311 531 SUPERFAMILY SSF63418 48 134 4.84E-9 T 18-10-2018 IPR035911 MurE/MurF, N-terminal TWT_225 3bf0be10d52ada007361b34795281311 531 Gene3D G3DSA:3.40.1190.10 136 365 2.6E-51 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_225 3bf0be10d52ada007361b34795281311 531 Gene3D G3DSA:3.40.1390.10 29 135 3.0E-14 T 18-10-2018 TWT_225 3bf0be10d52ada007361b34795281311 531 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 55 522 6.1E-91 T 18-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TWT_225 3bf0be10d52ada007361b34795281311 531 Pfam PF02875 Mur ligase family, glutamate ligase domain 372 455 2.5E-14 T 18-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TWT_225 3bf0be10d52ada007361b34795281311 531 Pfam PF08245 Mur ligase middle domain 144 346 8.9E-41 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_225 3bf0be10d52ada007361b34795281311 531 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 30 524 25.74 T 18-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 65 524 28.845 T 18-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 SUPERFAMILY SSF53244 387 524 2.15E-36 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Gene3D G3DSA:3.40.50.720 60 152 2.4E-15 T 18-10-2018 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Pfam PF02875 Mur ligase family, glutamate ligase domain 387 455 5.3E-8 T 18-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Gene3D G3DSA:3.40.1190.10 153 384 2.1E-39 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 SUPERFAMILY SSF53623 167 383 2.09E-38 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 68 522 7.4E-102 T 18-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Pfam PF08245 Mur ligase middle domain 173 308 5.8E-19 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Pfam PF01225 Mur ligase family, catalytic domain 67 153 1.4E-4 T 18-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 Gene3D G3DSA:3.90.190.20 386 520 4.8E-36 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 171 194 - T 18-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TWT_226 a94710e767cbe2083e3fcb4bfaa5100c 528 SUPERFAMILY SSF51984 61 152 3.79E-15 T 18-10-2018 TWT_748 dd653372917b03f4f9d0e6268d511a28 293 SUPERFAMILY SSF49493 107 192 2.35E-20 T 18-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TWT_748 dd653372917b03f4f9d0e6268d511a28 293 Pfam PF01556 DnaJ C terminal domain 115 258 7.6E-30 T 18-10-2018 IPR002939 Chaperone DnaJ, C-terminal TWT_748 dd653372917b03f4f9d0e6268d511a28 293 Gene3D G3DSA:1.10.287.110 13 110 6.3E-29 T 18-10-2018 IPR036869 Chaperone J-domain superfamily TWT_748 dd653372917b03f4f9d0e6268d511a28 293 PRINTS PR00625 DnaJ domain signature 36 51 1.0E-17 T 18-10-2018 IPR001623 DnaJ domain TWT_748 dd653372917b03f4f9d0e6268d511a28 293 PRINTS PR00625 DnaJ domain signature 53 73 1.0E-17 T 18-10-2018 IPR001623 DnaJ domain TWT_748 dd653372917b03f4f9d0e6268d511a28 293 PRINTS PR00625 DnaJ domain signature 18 36 1.0E-17 T 18-10-2018 IPR001623 DnaJ domain TWT_748 dd653372917b03f4f9d0e6268d511a28 293 SMART SM00271 15 73 4.3E-25 T 18-10-2018 IPR001623 DnaJ domain TWT_748 dd653372917b03f4f9d0e6268d511a28 293 Gene3D G3DSA:2.60.260.20 179 258 3.4E-24 T 18-10-2018 TWT_748 dd653372917b03f4f9d0e6268d511a28 293 Gene3D G3DSA:2.60.260.20 111 178 9.9E-16 T 18-10-2018 TWT_748 dd653372917b03f4f9d0e6268d511a28 293 SUPERFAMILY SSF49493 184 262 2.35E-19 T 18-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TWT_748 dd653372917b03f4f9d0e6268d511a28 293 Pfam PF00226 DnaJ domain 16 78 2.4E-24 T 18-10-2018 IPR001623 DnaJ domain TWT_748 dd653372917b03f4f9d0e6268d511a28 293 SUPERFAMILY SSF46565 15 104 2.09E-26 T 18-10-2018 IPR036869 Chaperone J-domain superfamily TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 235 1.7E-59 T 18-10-2018 TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.3E-42 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 Gene3D G3DSA:3.40.50.720 2 238 5.8E-78 T 18-10-2018 TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 175 1.2E-5 T 18-10-2018 TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 SUPERFAMILY SSF51735 4 236 5.56E-77 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.9E-10 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.9E-10 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_313 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.9E-10 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_631 5ffc217d5ba718d30b16772939a9abd7 257 Pfam PF13614 AAA domain 3 175 9.6E-33 T 18-10-2018 IPR025669 AAA domain TWT_631 5ffc217d5ba718d30b16772939a9abd7 257 Gene3D G3DSA:3.40.50.300 2 254 1.7E-54 T 18-10-2018 TWT_631 5ffc217d5ba718d30b16772939a9abd7 257 SUPERFAMILY SSF52540 2 249 1.07E-47 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 Gene3D G3DSA:3.20.20.105 16 404 6.8E-145 T 18-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 Pfam PF01702 Queuine tRNA-ribosyltransferase 168 396 6.3E-76 T 18-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 22 401 8.3E-127 T 18-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 SUPERFAMILY SSF51713 20 402 1.44E-129 T 18-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 22 402 3.2E-125 T 18-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_152 18bde7b841c5fb9c3360e38982f477bf 404 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 20 401 45.021 T 18-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_481 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 78 95 7.9E-44 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_481 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 7 22 7.9E-44 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_481 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 99 118 7.9E-44 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_481 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 156 175 7.9E-44 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_481 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 47 67 7.9E-44 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_481 9f9066062575b8f864003c9816621ed4 180 Pfam PF00574 Clp protease 3 178 4.1E-72 T 18-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TWT_481 9f9066062575b8f864003c9816621ed4 180 Gene3D G3DSA:3.90.226.10 1 180 1.2E-67 T 18-10-2018 TWT_481 9f9066062575b8f864003c9816621ed4 180 SUPERFAMILY SSF52096 6 179 5.68E-62 T 18-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TWT_481 9f9066062575b8f864003c9816621ed4 180 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 100 113 - T 18-10-2018 IPR033135 ClpP, histidine active site TWT_481 9f9066062575b8f864003c9816621ed4 180 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 180 34.872 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_483 1ab89141469b016301ef311ba5047c58 437 PIRSF PIRSF003095 321 432 1.3E-9 T 18-10-2018 IPR005215 Trigger factor GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 PIRSF PIRSF003095 5 328 1.2E-84 T 18-10-2018 IPR005215 Trigger factor GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 Gene3D G3DSA:3.10.50.40 157 259 1.8E-7 T 18-10-2018 TWT_483 1ab89141469b016301ef311ba5047c58 437 Gene3D G3DSA:3.30.70.1050 3 124 1.0E-25 T 18-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 Pfam PF05697 Bacterial trigger factor protein (TF) 10 148 2.3E-33 T 18-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 SUPERFAMILY SSF109998 262 420 2.75E-17 T 18-10-2018 IPR027304 Trigger factor/SurA domain superfamily TWT_483 1ab89141469b016301ef311ba5047c58 437 TIGRFAM TIGR00115 tig: trigger factor 16 403 3.9E-67 T 18-10-2018 IPR005215 Trigger factor GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 SUPERFAMILY SSF54534 139 260 5.65E-11 T 18-10-2018 TWT_483 1ab89141469b016301ef311ba5047c58 437 Hamap MF_00303 Trigger factor [tig]. 5 411 14.05 T 18-10-2018 IPR005215 Trigger factor GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 Gene3D G3DSA:1.10.3120.10 320 414 1.6E-6 T 18-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 SUPERFAMILY SSF102735 6 134 4.58E-29 T 18-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TWT_483 1ab89141469b016301ef311ba5047c58 437 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 326 402 1.6E-4 T 18-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 SUPERFAMILY SSF53335 255 435 7.48E-31 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 SMART SM00650 30 372 2.7E-39 T 18-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 SUPERFAMILY SSF53335 14 83 2.96E-20 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 Gene3D G3DSA:1.10.8.100 377 441 3.8E-16 T 18-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 Gene3D G3DSA:3.40.50.150 6 90 4.6E-21 T 18-10-2018 TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 Gene3D G3DSA:3.40.50.150 230 373 5.5E-26 T 18-10-2018 TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 Pfam PF00398 Ribosomal RNA adenine dimethylase 257 434 3.3E-22 T 18-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 82 2.4E-13 T 18-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TWT_203 c706b6aa966a882b8fc56eab7ece0f27 448 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 18-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TWT_264 aebed92eb32b6efb6c965ad644413831 287 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 1 287 47.243 T 18-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_264 aebed92eb32b6efb6c965ad644413831 287 ProSitePatterns PS01235 PdxS/SNZ family signature. 202 220 - T 18-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_264 aebed92eb32b6efb6c965ad644413831 287 SUPERFAMILY SSF51366 15 266 3.01E-57 T 18-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TWT_264 aebed92eb32b6efb6c965ad644413831 287 PIRSF PIRSF029271 1 287 2.7E-144 T 18-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_264 aebed92eb32b6efb6c965ad644413831 287 Pfam PF01680 SOR/SNZ family 5 209 7.4E-103 T 18-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_264 aebed92eb32b6efb6c965ad644413831 287 Gene3D G3DSA:3.20.20.70 2 287 2.0E-136 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_264 aebed92eb32b6efb6c965ad644413831 287 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 6 281 4.4E-137 T 18-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:1.20.1270.10 483 582 8.4E-22 T 18-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 18-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 5 352 1.1E-141 T 18-10-2018 TWT_750 90fe05b864ef639d000bb9b21893282b 603 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 578 4.1E-269 T 18-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TWT_750 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 18-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF100920 360 516 2.49E-62 T 18-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Pfam PF00012 Hsp70 protein 4 79 4.1E-30 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Pfam PF00012 Hsp70 protein 81 578 5.4E-207 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 162 341 1.1E-141 T 18-10-2018 TWT_750 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF53067 1 159 2.73E-59 T 18-10-2018 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 364 383 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 174 184 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 341 361 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 445 461 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 310 326 1.1E-73 T 18-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:2.60.34.10 353 482 3.5E-59 T 18-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 18-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.90.640.10 204 291 1.1E-141 T 18-10-2018 TWT_750 90fe05b864ef639d000bb9b21893282b 603 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 597 35.483 T 18-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TWT_750 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF53067 163 358 1.97E-62 T 18-10-2018 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 Pfam PF00318 Ribosomal protein S2 36 249 1.3E-82 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 31 249 2.8E-91 T 18-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 29 250 38.639 T 18-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 Gene3D G3DSA:3.40.50.10490 36 244 3.1E-78 T 18-10-2018 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 114 131 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 183 200 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 64 73 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 221 235 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 200 211 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 PRINTS PR00395 Ribosomal protein S2 signature 33 51 1.2E-33 T 18-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 Gene3D G3DSA:1.10.287.610 130 175 3.1E-78 T 18-10-2018 TWT_449 c7367e3575d0d71631d5b9c083c51f66 308 SUPERFAMILY SSF52313 33 257 2.88E-80 T 18-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 PIRSF PIRSF000130 2 491 9.4E-200 T 18-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 SUPERFAMILY SSF51412 8 481 5.76E-111 T 18-10-2018 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 SMART SM00116 162 210 6.0E-7 T 18-10-2018 IPR000644 CBS domain TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 SMART SM00116 98 146 4.0E-8 T 18-10-2018 IPR000644 CBS domain TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 Gene3D G3DSA:3.20.20.70 2 491 5.6E-196 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 Pfam PF00571 CBS domain 154 207 3.9E-8 T 18-10-2018 IPR000644 CBS domain TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 Pfam PF00571 CBS domain 95 140 3.8E-10 T 18-10-2018 IPR000644 CBS domain TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 459 2.4E-169 T 18-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 SMART SM01240 9 478 2.2E-274 T 18-10-2018 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 491 75.037 T 18-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 301 313 - T 18-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 SUPERFAMILY SSF54631 66 207 3.54E-30 T 18-10-2018 TWT_075 fecf9dd72d6ed7f54d7bb0f6e726f967 491 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 478 5.0E-146 T 18-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 Gene3D G3DSA:3.30.63.10 154 216 9.1E-56 T 18-10-2018 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 Pfam PF00625 Guanylate kinase 126 298 9.4E-37 T 18-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 124 299 9.4E-64 T 18-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 ProSitePatterns PS00856 Guanylate kinase-like signature. 157 174 - T 18-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 Hamap MF_00328 Guanylate kinase [gmk]. 121 304 31.536 T 18-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 Gene3D G3DSA:1.10.8.50 7 106 3.2E-15 T 18-10-2018 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 SUPERFAMILY SSF52540 124 301 1.88E-50 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 Gene3D G3DSA:3.40.50.300 126 297 9.1E-56 T 18-10-2018 TWT_363 042da9efbcae0d8cd9fa7a136d722cc5 304 SMART SM00072 123 298 3.1E-39 T 18-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TWT_754 4dba5c53fca4d77d393d0c5772036781 446 Pfam PF01336 OB-fold nucleic acid binding domain 32 108 2.5E-8 T 18-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 SUPERFAMILY SSF55681 126 433 3.85E-77 T 18-10-2018 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 PRINTS PR01042 Aspartyl-tRNA synthetase signature 214 227 3.8E-19 T 18-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 209 3.8E-19 T 18-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 PRINTS PR01042 Aspartyl-tRNA synthetase signature 401 415 3.8E-19 T 18-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 PRINTS PR01042 Aspartyl-tRNA synthetase signature 361 377 3.8E-19 T 18-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 15 446 36.315 T 18-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 SUPERFAMILY SSF50249 12 120 2.36E-13 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_754 4dba5c53fca4d77d393d0c5772036781 446 Gene3D G3DSA:2.40.50.140 6 117 3.1E-18 T 18-10-2018 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 Gene3D G3DSA:3.30.930.10 121 435 5.8E-89 T 18-10-2018 TWT_754 4dba5c53fca4d77d393d0c5772036781 446 Pfam PF00152 tRNA synthetases class II (D, K and N) 128 436 1.2E-75 T 18-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_076 580c9332696593cabeaf47317cc4fab7 384 Gene3D G3DSA:3.20.20.70 23 376 1.2E-76 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_076 580c9332696593cabeaf47317cc4fab7 384 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 13 375 2.4E-150 T 18-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 TWT_076 580c9332696593cabeaf47317cc4fab7 384 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 24 304 3.1E-29 T 18-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TWT_076 580c9332696593cabeaf47317cc4fab7 384 SMART SM01240 22 378 3.6E-13 T 18-10-2018 TWT_076 580c9332696593cabeaf47317cc4fab7 384 SUPERFAMILY SSF51412 18 378 5.36E-55 T 18-10-2018 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 Gene3D G3DSA:3.40.50.150 86 282 5.4E-42 T 18-10-2018 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 190 196 - T 18-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 277 6.3E-63 T 18-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 Gene3D G3DSA:1.10.8.10 2 85 2.6E-16 T 18-10-2018 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 SUPERFAMILY SSF53335 64 248 3.23E-37 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 279 5.0E-48 T 18-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TWT_434 c786251c2ad5bef36d3267ebe2d4e9ea 285 Pfam PF05175 Methyltransferase small domain 103 200 1.1E-9 T 18-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF04563 RNA polymerase beta subunit 68 443 7.7E-23 T 18-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:2.30.150.10 539 606 0.0 T 18-10-2018 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 54 1156 12.039 T 18-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF10385 RNA polymerase beta subunit external 1 domain 536 602 1.3E-25 T 18-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 278 874 5.2E-284 T 18-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF04560 RNA polymerase Rpb2, domain 7 1080 1154 2.1E-25 T 18-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 SUPERFAMILY SSF64484 54 1159 0.0 T 18-10-2018 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF04565 RNA polymerase Rpb2, domain 3 458 526 1.2E-27 T 18-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:3.90.1100.10 59 663 0.0 T 18-10-2018 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:2.40.50.100 664 738 0.0 T 18-10-2018 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF00562 RNA polymerase Rpb2, domain 6 664 1078 5.1E-148 T 18-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:2.40.270.10 57 1056 0.0 T 18-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 ProSitePatterns PS01166 RNA polymerases beta chain signature. 903 915 - T 18-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:2.40.50.150 774 901 0.0 T 18-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Pfam PF04561 RNA polymerase Rpb2, domain 2 202 399 1.2E-24 T 18-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:3.90.1110.10 207 393 0.0 T 18-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_071 17213f4b0dfa86c08de0ed203c4e0278 1188 Gene3D G3DSA:3.90.1800.10 1065 1152 2.7E-10 T 18-10-2018 TWT_051 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.30.300.20 601 681 5.4E-20 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_051 154e32e03b258180a82945121fc05656 686 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 601 679 5.9E-19 T 18-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TWT_051 154e32e03b258180a82945121fc05656 686 Hamap MF_00238 Cytidylate kinase [cmk]. 5 231 23.318 T 18-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TWT_051 154e32e03b258180a82945121fc05656 686 Pfam PF01926 50S ribosome-binding GTPase 427 545 3.5E-22 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 Pfam PF01926 50S ribosome-binding GTPase 257 371 1.8E-21 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 256 679 7.6E-147 T 18-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 477 492 5.7E-7 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 428 448 5.7E-7 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 426 588 2.5E-18 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 256 410 7.6E-23 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 Pfam PF02224 Cytidylate kinase 7 228 5.3E-42 T 18-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TWT_051 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 2 232 1.5E-51 T 18-10-2018 TWT_051 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 255 413 3.7E-41 T 18-10-2018 TWT_051 154e32e03b258180a82945121fc05656 686 Hamap MF_00195 GTPase Der [der]. 254 682 32.626 T 18-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TWT_051 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 389 679 5.18E-52 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_051 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 256 414 6.95E-39 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_051 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 6 229 7.63E-20 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_051 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 424 597 1.4E-42 T 18-10-2018 TWT_114 45d53e62353d49a492d00d387a833eb2 56 Pfam PF00471 Ribosomal protein L33 11 56 3.1E-16 T 18-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_114 45d53e62353d49a492d00d387a833eb2 56 SUPERFAMILY SSF57829 5 56 2.87E-17 T 18-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TWT_114 45d53e62353d49a492d00d387a833eb2 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 56 14.339 T 18-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_114 45d53e62353d49a492d00d387a833eb2 56 Gene3D G3DSA:2.20.28.120 1 56 2.8E-23 T 18-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_114 45d53e62353d49a492d00d387a833eb2 56 ProSitePatterns PS00582 Ribosomal protein L33 signature. 24 43 - T 18-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_114 45d53e62353d49a492d00d387a833eb2 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 56 2.5E-21 T 18-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 SUPERFAMILY SSF52518 18 215 5.54E-58 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 SMART SM00861 18 191 1.0E-57 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 Gene3D G3DSA:3.40.50.970 17 202 1.3E-64 T 18-10-2018 TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 Pfam PF02779 Transketolase, pyrimidine binding domain 19 189 1.1E-40 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 SUPERFAMILY SSF52922 203 332 2.62E-34 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 Gene3D G3DSA:3.40.50.920 203 334 3.9E-42 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_789 bc8e203b06f2a1ca5714a11da33058d1 334 Pfam PF02780 Transketolase, C-terminal domain 207 324 2.5E-31 T 18-10-2018 IPR033248 Transketolase, C-terminal domain TWT_453 e35ed8b034b4bbfff0cd831a23a7b16d 399 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 128 321 1.2E-58 T 18-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TWT_453 e35ed8b034b4bbfff0cd831a23a7b16d 399 Gene3D G3DSA:3.40.50.450 25 326 5.8E-75 T 18-10-2018 TWT_453 e35ed8b034b4bbfff0cd831a23a7b16d 399 Pfam PF02481 DNA recombination-mediator protein A 128 315 2.1E-61 T 18-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TWT_453 e35ed8b034b4bbfff0cd831a23a7b16d 399 SUPERFAMILY SSF102405 127 320 6.59E-26 T 18-10-2018 TWT_035 f7b2e332b1ebeae1613aa615239cbeff 297 Pfam PF01061 ABC-2 type transporter 40 251 1.2E-18 T 18-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TWT_778 a418b616a6d7506ee891e425e479da0f 550 SUPERFAMILY SSF54184 348 408 7.72E-6 T 18-10-2018 TWT_778 a418b616a6d7506ee891e425e479da0f 550 Pfam PF03793 PASTA domain 413 466 7.5E-5 T 18-10-2018 IPR005543 PASTA domain TWT_778 a418b616a6d7506ee891e425e479da0f 550 Pfam PF03793 PASTA domain 349 408 2.1E-13 T 18-10-2018 IPR005543 PASTA domain TWT_778 a418b616a6d7506ee891e425e479da0f 550 Pfam PF00069 Protein kinase domain 91 255 2.2E-8 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_778 a418b616a6d7506ee891e425e479da0f 550 Gene3D G3DSA:3.30.200.20 2 96 1.4E-6 T 18-10-2018 TWT_778 a418b616a6d7506ee891e425e479da0f 550 SUPERFAMILY SSF56112 9 260 6.53E-21 T 18-10-2018 IPR011009 Protein kinase-like domain superfamily TWT_778 a418b616a6d7506ee891e425e479da0f 550 Gene3D G3DSA:3.30.10.20 347 411 4.6E-12 T 18-10-2018 TWT_778 a418b616a6d7506ee891e425e479da0f 550 SUPERFAMILY SSF54184 412 466 1.96E-7 T 18-10-2018 TWT_778 a418b616a6d7506ee891e425e479da0f 550 Gene3D G3DSA:1.10.510.10 110 282 4.8E-17 T 18-10-2018 TWT_778 a418b616a6d7506ee891e425e479da0f 550 SMART SM00220 14 271 0.0079 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_778 a418b616a6d7506ee891e425e479da0f 550 SMART SM00740 344 409 8.2E-8 T 18-10-2018 IPR005543 PASTA domain TWT_778 a418b616a6d7506ee891e425e479da0f 550 SMART SM00740 413 468 6.1 T 18-10-2018 IPR005543 PASTA domain TWT_278 ac017822016e93eab3ec0871026da9a2 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 7.8E-8 T 18-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.9E-13 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 PRINTS PR00315 GTP-binding elongation factor signature 55 63 6.9E-13 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.9E-13 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.9E-13 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.9E-13 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 Pfam PF06421 GTP-binding protein LepA C-terminus 493 597 4.9E-46 T 18-10-2018 IPR013842 GTP-binding protein LepA, C-terminal TWT_278 ac017822016e93eab3ec0871026da9a2 601 SUPERFAMILY SSF52540 6 235 2.42E-53 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_278 ac017822016e93eab3ec0871026da9a2 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 181 1.1E-18 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 SUPERFAMILY SSF54980 296 375 2.34E-17 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_278 ac017822016e93eab3ec0871026da9a2 601 Pfam PF00679 Elongation factor G C-terminus 403 490 1.4E-19 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_278 ac017822016e93eab3ec0871026da9a2 601 SUPERFAMILY SSF54980 403 498 3.12E-22 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_278 ac017822016e93eab3ec0871026da9a2 601 Gene3D G3DSA:3.40.50.300 7 190 1.7E-67 T 18-10-2018 TWT_278 ac017822016e93eab3ec0871026da9a2 601 Gene3D G3DSA:2.40.30.10 191 289 5.5E-32 T 18-10-2018 TWT_278 ac017822016e93eab3ec0871026da9a2 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 18-10-2018 IPR031157 Tr-type G domain, conserved site TWT_278 ac017822016e93eab3ec0871026da9a2 601 SMART SM00838 402 486 0.0013 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_278 ac017822016e93eab3ec0871026da9a2 601 Pfam PF00009 Elongation factor Tu GTP binding domain 9 186 4.2E-50 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 Gene3D G3DSA:3.30.70.2570 484 558 3.8E-32 T 18-10-2018 IPR038363 LepA, C-terminal domain superfamily TWT_278 ac017822016e93eab3ec0871026da9a2 601 Gene3D G3DSA:3.30.70.870 291 372 1.9E-32 T 18-10-2018 TWT_278 ac017822016e93eab3ec0871026da9a2 601 Gene3D G3DSA:3.30.70.3380 373 483 1.9E-36 T 18-10-2018 TWT_278 ac017822016e93eab3ec0871026da9a2 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 257.621 T 18-10-2018 IPR006297 Elongation factor 4 GO:0005525 TWT_278 ac017822016e93eab3ec0871026da9a2 601 TIGRFAM TIGR01393 lepA: elongation factor 4 9 598 1.9E-272 T 18-10-2018 IPR006297 Elongation factor 4 GO:0005525 TWT_792 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:3.90.170.10 265 427 2.1E-63 T 18-10-2018 TWT_792 7c6bc38808de052fa57200ae50408b48 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 18-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 187.167 T 18-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 SUPERFAMILY SSF52540 3 424 7.86E-168 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_792 7c6bc38808de052fa57200ae50408b48 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 2.3E-157 T 18-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 4.5E-172 T 18-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:1.10.300.10 106 205 7.4E-96 T 18-10-2018 TWT_792 7c6bc38808de052fa57200ae50408b48 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 18-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 SMART SM00788 3 422 2.9E-272 T 18-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TWT_792 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:3.40.440.10 5 257 7.4E-96 T 18-10-2018 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 65 131 1.4E-27 T 18-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 Gene3D G3DSA:1.20.5.710 9 61 5.5E-17 T 18-10-2018 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 SUPERFAMILY SSF54736 61 131 1.62E-22 T 18-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 8 131 22.787 T 18-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 SUPERFAMILY SSF48300 10 67 1.7E-13 T 18-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 66 105 4.0E-15 T 18-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 Gene3D G3DSA:3.30.1390.10 62 131 8.2E-29 T 18-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 10 59 1.1E-16 T 18-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_711 d7d6362eac2661ed154bc0faf27a1f5f 131 TIGRFAM TIGR00855 L12: ribosomal protein bL12 6 131 2.8E-44 T 18-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 SUPERFAMILY SSF89095 354 501 9.68E-17 T 18-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 Pfam PF02637 GatB domain 358 501 2.0E-29 T 18-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 Pfam PF02934 GatB/GatE catalytic domain 17 317 1.1E-95 T 18-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 13 502 31.108 T 18-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 SUPERFAMILY SSF55931 16 325 5.62E-99 T 18-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 SMART SM00845 356 501 8.4E-33 T 18-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 168 182 - T 18-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 Gene3D G3DSA:1.10.10.410 441 502 3.0E-12 T 18-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 13 501 5.1E-127 T 18-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TWT_411 991b8b5b5c3750f0fa0107d8f2680059 504 Gene3D G3DSA:1.10.150.380 326 440 3.6E-9 T 18-10-2018 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Pfam PF00271 Helicase conserved C-terminal domain 436 548 4.3E-17 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_295 2ee1166a60611da2103f0353fae4794e 677 SUPERFAMILY SSF46600 625 665 1.24E-10 T 18-10-2018 IPR036876 UVR domain superfamily TWT_295 2ee1166a60611da2103f0353fae4794e 677 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 664 41.87 T 18-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TWT_295 2ee1166a60611da2103f0353fae4794e 677 SMART SM00490 463 549 4.5E-20 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_295 2ee1166a60611da2103f0353fae4794e 677 Gene3D G3DSA:3.40.50.300 271 417 2.8E-52 T 18-10-2018 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Gene3D G3DSA:3.40.50.300 9 167 8.5E-69 T 18-10-2018 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Gene3D G3DSA:3.30.2060.10 168 249 1.0E-14 T 18-10-2018 TWT_295 2ee1166a60611da2103f0353fae4794e 677 SUPERFAMILY SSF52540 38 594 6.93E-34 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_295 2ee1166a60611da2103f0353fae4794e 677 Pfam PF12344 Ultra-violet resistance protein B 555 596 1.5E-19 T 18-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain TWT_295 2ee1166a60611da2103f0353fae4794e 677 SUPERFAMILY SSF52540 8 418 5.05E-129 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_295 2ee1166a60611da2103f0353fae4794e 677 Pfam PF02151 UvrB/uvrC motif 632 663 9.9E-8 T 18-10-2018 IPR001943 UVR domain GO:0005515 TWT_295 2ee1166a60611da2103f0353fae4794e 677 SMART SM00487 14 429 7.0E-23 T 18-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TWT_295 2ee1166a60611da2103f0353fae4794e 677 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 10 662 0.0 T 18-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Gene3D G3DSA:3.40.50.300 418 599 8.4E-50 T 18-10-2018 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Pfam PF04851 Type III restriction enzyme, res subunit 21 97 5.4E-9 T 18-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TWT_295 2ee1166a60611da2103f0353fae4794e 677 Gene3D G3DSA:4.10.860.10 616 668 8.6E-11 T 18-10-2018 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.218 T 18-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 Gene3D G3DSA:3.30.420.80 2 130 5.3E-54 T 18-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 127 8.1E-56 T 18-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 PIRSF PIRSF002131 1 130 4.5E-54 T 18-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 Pfam PF00411 Ribosomal protein S11 20 128 2.0E-46 T 18-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TWT_529 90b249ac0c4d07fa44d858c30880307f 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 18-10-2018 IPR018102 Ribosomal S11, conserved site TWT_529 90b249ac0c4d07fa44d858c30880307f 130 SUPERFAMILY SSF53137 15 128 1.31E-46 T 18-10-2018 TWT_558 f824e70d27805f4121b4c681bb36e01b 270 Pfam PF00005 ABC transporter 37 197 4.5E-33 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_558 f824e70d27805f4121b4c681bb36e01b 270 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 268 4.6E-11 T 18-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TWT_558 f824e70d27805f4121b4c681bb36e01b 270 Gene3D G3DSA:3.40.50.300 16 269 4.8E-63 T 18-10-2018 TWT_558 f824e70d27805f4121b4c681bb36e01b 270 SMART SM00382 46 254 1.4E-7 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_558 f824e70d27805f4121b4c681bb36e01b 270 SUPERFAMILY SSF52540 20 268 4.79E-66 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_222 6570b474963d97535a1f1fd9e27b7600 581 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 559 2.0E-55 T 18-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TWT_222 6570b474963d97535a1f1fd9e27b7600 581 SUPERFAMILY SSF56601 229 571 2.73E-68 T 18-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TWT_222 6570b474963d97535a1f1fd9e27b7600 581 SUPERFAMILY SSF56519 47 228 5.1E-34 T 18-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TWT_222 6570b474963d97535a1f1fd9e27b7600 581 Pfam PF03717 Penicillin-binding Protein dimerisation domain 51 208 3.9E-12 T 18-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TWT_222 6570b474963d97535a1f1fd9e27b7600 581 Gene3D G3DSA:3.40.710.10 290 484 9.2E-83 T 18-10-2018 TWT_222 6570b474963d97535a1f1fd9e27b7600 581 Gene3D G3DSA:3.30.450.330 230 564 9.2E-83 T 18-10-2018 TWT_222 6570b474963d97535a1f1fd9e27b7600 581 Gene3D G3DSA:3.90.1310.30 44 228 9.8E-33 T 18-10-2018 TWT_086 ac33019b1e35e50c53918d282cfa1545 377 Gene3D G3DSA:1.20.1250.20 1 188 2.6E-21 T 18-10-2018 TWT_086 ac33019b1e35e50c53918d282cfa1545 377 Gene3D G3DSA:1.20.1250.20 196 372 8.9E-14 T 18-10-2018 TWT_086 ac33019b1e35e50c53918d282cfa1545 377 Pfam PF07690 Major Facilitator Superfamily 9 309 2.1E-30 T 18-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TWT_086 ac33019b1e35e50c53918d282cfa1545 377 SUPERFAMILY SSF103473 2 367 2.75E-44 T 18-10-2018 IPR036259 MFS transporter superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.5E-94 T 18-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-69 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 PRINTS PR00298 60kDa chaperonin signature 396 417 1.5E-69 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 PRINTS PR00298 60kDa chaperonin signature 348 373 1.5E-69 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 PRINTS PR00298 60kDa chaperonin signature 266 289 1.5E-69 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-69 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 SUPERFAMILY SSF48592 6 519 2.33E-69 T 18-10-2018 IPR027413 GroEL-like equatorial domain superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 Gene3D G3DSA:1.10.560.10 7 519 7.1E-220 T 18-10-2018 IPR027413 GroEL-like equatorial domain superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 SUPERFAMILY SSF52029 183 374 2.24E-82 T 18-10-2018 IPR027409 GroEL-like apical domain superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 Gene3D G3DSA:3.30.260.10 135 408 7.1E-220 T 18-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 Gene3D G3DSA:3.50.7.10 190 370 7.1E-220 T 18-10-2018 IPR027409 GroEL-like apical domain superfamily TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 18-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.2E-242 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 40.05 T 18-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TWT_441 f445c8ebafa3cbab0abf795522751fbf 540 SUPERFAMILY SSF54849 136 202 9.39E-25 T 18-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TWT_495 3cc0de5b5784958d937a9a90bb029278 224 Gene3D G3DSA:3.20.20.10 14 79 3.0E-6 T 18-10-2018 IPR029066 PLP-binding barrel TWT_495 3cc0de5b5784958d937a9a90bb029278 224 SUPERFAMILY SSF50621 97 222 1.64E-27 T 18-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TWT_495 3cc0de5b5784958d937a9a90bb029278 224 Gene3D G3DSA:2.40.37.10 88 223 3.7E-29 T 18-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TWT_495 3cc0de5b5784958d937a9a90bb029278 224 Pfam PF00842 Alanine racemase, C-terminal domain 104 220 2.9E-27 T 18-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_495 3cc0de5b5784958d937a9a90bb029278 224 SMART SM01005 103 223 7.2E-36 T 18-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_694 a6fe5ad63060df43469f04956fc70193 411 Gene3D G3DSA:3.40.50.300 29 201 5.2E-31 T 18-10-2018 TWT_694 a6fe5ad63060df43469f04956fc70193 411 SUPERFAMILY SSF52540 40 242 1.16E-31 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_694 a6fe5ad63060df43469f04956fc70193 411 Pfam PF13177 DNA polymerase III, delta subunit 47 202 3.0E-26 T 18-10-2018 TWT_480 e31cbf5d308767b267e776e5b972a247 207 Gene3D G3DSA:3.90.226.10 1 203 9.9E-74 T 18-10-2018 TWT_480 e31cbf5d308767b267e776e5b972a247 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 18-10-2018 IPR033135 ClpP, histidine active site TWT_480 e31cbf5d308767b267e776e5b972a247 207 Pfam PF00574 Clp protease 21 199 2.9E-73 T 18-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TWT_480 e31cbf5d308767b267e776e5b972a247 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 200 39.181 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 SUPERFAMILY SSF52096 17 200 3.08E-62 T 18-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TWT_480 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 8.7E-42 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 8.7E-42 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 8.7E-42 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 8.7E-42 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 175 194 8.7E-42 T 18-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TWT_480 e31cbf5d308767b267e776e5b972a247 207 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 95 106 - T 18-10-2018 IPR018215 ClpP, Ser active site TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 PIRSF PIRSF002191 2 115 9.6E-49 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 18-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 28.507 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 112 2.9E-46 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 7.7E-38 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 7.7E-38 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 7.7E-38 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 SUPERFAMILY SSF50104 4 114 9.23E-44 T 18-10-2018 IPR008991 Translation protein SH3-like domain superfamily TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 Pfam PF01245 Ribosomal protein L19 5 112 6.0E-47 T 18-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_457 60d60f5ec2ac9368992db2cebd56b9bc 115 Gene3D G3DSA:2.30.30.790 8 114 2.3E-16 T 18-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_519 a0068246854c84a04745d13aee625ea5 973 Pfam PF13361 UvrD-like helicase C-terminal domain 322 692 7.1E-23 T 18-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TWT_519 a0068246854c84a04745d13aee625ea5 973 Gene3D G3DSA:3.40.50.300 16 175 2.1E-31 T 18-10-2018 TWT_519 a0068246854c84a04745d13aee625ea5 973 SUPERFAMILY SSF52540 18 709 4.89E-95 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_519 a0068246854c84a04745d13aee625ea5 973 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 315 8.0E-43 T 18-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TWT_519 a0068246854c84a04745d13aee625ea5 973 Gene3D G3DSA:3.40.50.300 360 456 5.5E-9 T 18-10-2018 TWT_519 a0068246854c84a04745d13aee625ea5 973 Pfam PF12705 PD-(D/E)XK nuclease superfamily 803 961 4.1E-6 T 18-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TWT_519 a0068246854c84a04745d13aee625ea5 973 Gene3D G3DSA:3.40.50.300 213 342 1.4E-30 T 18-10-2018 TWT_519 a0068246854c84a04745d13aee625ea5 973 SUPERFAMILY SSF52980 794 933 1.07E-8 T 18-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TWT_598 243b90f3d111c31eb96e3cc51cc2fb5d 232 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 7 221 1.0E-112 T 18-10-2018 TWT_598 243b90f3d111c31eb96e3cc51cc2fb5d 232 Pfam PF13829 Domain of unknown function (DUF4191) 6 224 8.2E-49 T 18-10-2018 IPR025445 Protein of unknown function DUF4191 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 SUPERFAMILY SSF51621 19 269 2.94E-81 T 18-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 Pfam PF02548 Ketopantoate hydroxymethyltransferase 20 266 5.3E-90 T 18-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 16 269 2.8E-78 T 18-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 11 271 35.832 T 18-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 Gene3D G3DSA:3.20.20.60 12 270 5.6E-90 T 18-10-2018 TWT_260 0430663b7d1f6d20eefec9d7a8c37ef0 272 PIRSF PIRSF000388 4 272 4.4E-104 T 18-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 SUPERFAMILY SSF54814 256 315 5.1E-14 T 18-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 72 316 2.4E-81 T 18-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 SUPERFAMILY SSF54814 176 254 2.78E-25 T 18-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Gene3D G3DSA:3.30.1480.10 3 96 1.3E-11 T 18-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Gene3D G3DSA:2.40.50.140 103 174 2.2E-16 T 18-10-2018 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 319 21.158 T 18-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 SUPERFAMILY SSF50249 107 175 5.0E-11 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 SUPERFAMILY SSF69705 2 95 4.05E-16 T 18-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Gene3D G3DSA:3.30.300.20 254 317 6.2E-23 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Gene3D G3DSA:3.30.300.20 175 253 4.3E-29 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_156 c1aebedf5369840e4e071e13b7b984d8 319 Pfam PF13184 NusA-like KH domain 206 273 2.1E-21 T 18-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TWT_634 1412f6ee95c240418039455507fc35d5 295 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 18-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 SUPERFAMILY SSF51735 122 285 6.4E-37 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_634 1412f6ee95c240418039455507fc35d5 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 288 33.802 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 286 8.6E-54 T 18-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 Gene3D G3DSA:3.40.50.720 6 264 2.5E-98 T 18-10-2018 TWT_634 1412f6ee95c240418039455507fc35d5 295 Gene3D G3DSA:3.40.50.10860 8 281 2.5E-98 T 18-10-2018 TWT_634 1412f6ee95c240418039455507fc35d5 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 8.9E-35 T 18-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 261 279 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 4.0E-65 T 18-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TWT_634 1412f6ee95c240418039455507fc35d5 295 SUPERFAMILY SSF53223 2 121 3.36E-34 T 18-10-2018 TWT_734 c4001cd9f89b1c8c742d603a27881429 215 SUPERFAMILY SSF54909 4 214 7.24E-58 T 18-10-2018 IPR011008 Dimeric alpha-beta barrel TWT_734 c4001cd9f89b1c8c742d603a27881429 215 Gene3D G3DSA:3.30.70.1100 96 215 2.5E-28 T 18-10-2018 TWT_734 c4001cd9f89b1c8c742d603a27881429 215 Pfam PF06778 Chlorite dismutase 38 203 1.1E-49 T 18-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Pfam PF00005 ABC transporter 607 868 1.2E-9 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 SUPERFAMILY SSF52540 9 557 1.41E-43 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:3.30.190.20 134 244 1.7E-217 T 18-10-2018 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:1.10.8.280 288 391 1.7E-217 T 18-10-2018 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 ProSitePatterns PS00211 ABC transporters family signature. 838 852 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 SUPERFAMILY SSF52540 598 922 1.29E-48 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 8 657 6.3E-242 T 18-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:3.40.50.300 600 944 4.8E-134 T 18-10-2018 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:1.20.1580.10 94 480 1.7E-217 T 18-10-2018 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:3.40.50.300 10 580 1.7E-217 T 18-10-2018 TWT_296 9ef56cbf7e69aa2700e77f2982ced5ec 948 Gene3D G3DSA:1.20.1580.10 700 838 4.8E-134 T 18-10-2018 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 Pfam PF03725 3' exoribonuclease family, domain 2 177 242 2.8E-13 T 18-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 Gene3D G3DSA:3.30.230.70 28 256 1.2E-57 T 18-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 21 255 5.3E-102 T 18-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 SUPERFAMILY SSF55666 170 253 6.41E-23 T 18-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 ProSitePatterns PS01277 Ribonuclease PH signature. 135 148 - T 18-10-2018 IPR018336 Ribonuclease PH, conserved site TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 Pfam PF01138 3' exoribonuclease family, domain 1 29 159 2.4E-18 T 18-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 SUPERFAMILY SSF54211 16 200 6.07E-40 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_622 1acb2fdbc2f174ab81d82dc73ffe462c 256 Hamap MF_00564 Ribonuclease PH [rph]. 30 256 40.955 T 18-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 Gene3D G3DSA:3.40.50.1220 204 326 7.4E-13 T 18-10-2018 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 527 25.379 T 18-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 SUPERFAMILY SSF52518 11 182 5.4E-27 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_068 0ce3051185ac4f7c15611442976b18a9 527 Gene3D G3DSA:3.40.50.970 355 526 6.7E-42 T 18-10-2018 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 175 2.1E-26 T 18-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 SUPERFAMILY SSF52518 357 515 9.38E-18 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_068 0ce3051185ac4f7c15611442976b18a9 527 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 8 418 2.3E-103 T 18-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 PIRSF PIRSF004983 1 526 6.3E-143 T 18-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TWT_068 0ce3051185ac4f7c15611442976b18a9 527 Gene3D G3DSA:3.40.50.970 2 173 7.2E-54 T 18-10-2018 TWT_348 a70762eb7e8686740af5ed451fde9667 422 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 302 317 - T 18-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 267 421 23.882 T 18-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 Pfam PF02542 YgbB family 269 419 3.6E-37 T 18-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 SUPERFAMILY SSF69765 268 420 7.59E-41 T 18-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 Gene3D G3DSA:3.30.1330.50 263 422 6.2E-43 T 18-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 SUPERFAMILY SSF53448 5 238 1.92E-38 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_348 a70762eb7e8686740af5ed451fde9667 422 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 239 4.1E-41 T 18-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 422 32.231 T 18-10-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 TWT_348 a70762eb7e8686740af5ed451fde9667 422 Gene3D G3DSA:3.90.550.10 2 242 1.1E-52 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 Pfam PF03719 Ribosomal protein S5, C-terminal domain 190 260 6.0E-28 T 18-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 Gene3D G3DSA:3.30.160.20 107 175 6.2E-29 T 18-10-2018 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 Pfam PF00333 Ribosomal protein S5, N-terminal domain 115 178 3.4E-27 T 18-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 SUPERFAMILY SSF54768 112 179 5.86E-22 T 18-10-2018 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 113 262 5.6E-65 T 18-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 Gene3D G3DSA:3.30.230.10 179 270 2.6E-33 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 ProSitePatterns PS00585 Ribosomal protein S5 signature. 131 163 - T 18-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 90 266 33.828 T 18-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TWT_538 05465d3723b2d7724b85b4b6aa5a26ee 286 SUPERFAMILY SSF54211 182 261 5.82E-24 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Gene3D G3DSA:3.40.50.1000 394 657 1.9E-70 T 18-10-2018 IPR023214 HAD superfamily TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 SUPERFAMILY SSF55008 5 70 8.77E-12 T 18-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Gene3D G3DSA:2.70.150.20 211 320 5.0E-27 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Gene3D G3DSA:3.30.70.100 7 69 1.7E-11 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 ProSitePatterns PS01229 Hypothetical cof family signature 2. 605 627 - T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Pfam PF00122 E1-E2 ATPase 218 389 7.0E-48 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 SUPERFAMILY SSF56784 409 705 1.75E-50 T 18-10-2018 IPR036412 HAD-like superfamily TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 130 708 1.5E-136 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 5.7E-20 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 624 5.7E-20 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 265 279 5.7E-20 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 411 425 5.7E-20 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 640 5.7E-20 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Pfam PF00702 haloacid dehalogenase-like hydrolase 409 619 2.4E-36 T 18-10-2018 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 413 419 - T 18-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Pfam PF00403 Heavy-metal-associated domain 9 46 7.9E-7 T 18-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 SUPERFAMILY SSF81653 226 315 1.26E-19 T 18-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 190 692 1.5E-69 T 18-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 Gene3D G3DSA:3.40.1110.10 422 537 1.9E-70 T 18-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 148 706 1.3E-149 T 18-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TWT_803 08ffef64514c5a6b0d856ef5e30965d4 716 SUPERFAMILY SSF81665 187 405 5.49E-9 T 18-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TWT_433 9d2618038422ed4deae61160f6ab6306 225 SUPERFAMILY SSF55821 3 181 3.36E-44 T 18-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TWT_433 9d2618038422ed4deae61160f6ab6306 225 Gene3D G3DSA:3.90.870.10 4 222 1.8E-48 T 18-10-2018 TWT_433 9d2618038422ed4deae61160f6ab6306 225 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 14 181 3.3E-39 T 18-10-2018 IPR006070 YrdC-like domain GO:0003725 TWT_433 9d2618038422ed4deae61160f6ab6306 225 Pfam PF01300 Telomere recombination 22 181 1.6E-38 T 18-10-2018 IPR006070 YrdC-like domain GO:0003725 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 105 121 5.7E-17 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 189 211 5.7E-17 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 250 265 5.7E-17 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 264 1.4E-41 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 Pfam PF00119 ATP synthase A chain 49 263 3.1E-46 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 Hamap MF_01393 ATP synthase subunit a [atpB]. 26 270 12.655 T 18-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 SUPERFAMILY SSF81336 96 263 2.22E-34 T 18-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_430 feb672199d7ddd0034f32968096bcb1b 271 Gene3D G3DSA:1.20.120.220 97 271 2.4E-25 T 18-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_780 3364f25007163f9428039c15083fe1bb 442 Gene3D G3DSA:3.50.50.100 2 407 4.0E-88 T 18-10-2018 TWT_780 3364f25007163f9428039c15083fe1bb 442 SUPERFAMILY SSF51905 4 209 5.11E-25 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_780 3364f25007163f9428039c15083fe1bb 442 SUPERFAMILY SSF51905 158 344 1.3E-16 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_780 3364f25007163f9428039c15083fe1bb 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.7E-9 T 18-10-2018 TWT_780 3364f25007163f9428039c15083fe1bb 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.7E-9 T 18-10-2018 TWT_780 3364f25007163f9428039c15083fe1bb 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 1.7E-9 T 18-10-2018 TWT_780 3364f25007163f9428039c15083fe1bb 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 333 1.9E-41 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PIRSF PIRSF001415 2 325 3.1E-118 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 243 255 - T 18-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 SMART SM01004 5 322 4.8E-169 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 321 1.6E-114 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 SUPERFAMILY SSF51569 4 324 3.66E-110 T 18-10-2018 TWT_730 92bf14ad529152c683332c6b822b4d62 326 Gene3D G3DSA:3.20.20.70 3 326 1.6E-115 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 192 211 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 268 283 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 123 137 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 243 259 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_730 92bf14ad529152c683332c6b822b4d62 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 154 173 2.3E-48 T 18-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.1790.20 1003 1180 1.1E-67 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1243 17.343 T 18-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.132.30 709 843 3.2E-49 T 18-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Pfam PF04983 RNA polymerase Rpb1, domain 3 562 712 9.0E-22 T 18-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 SUPERFAMILY SSF64484 4 1230 0.0 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Pfam PF00623 RNA polymerase Rpb1, domain 2 417 558 8.1E-35 T 18-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.274.100 631 708 8.0E-16 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 7 1233 0.0 T 18-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 SMART SM00663 308 587 6.6E-166 T 18-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.40.90 447 489 5.5E-19 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.274.100 563 630 3.1E-19 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:2.40.50.100 1019 1081 1.1E-67 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 415 1.2E-77 T 18-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Gene3D G3DSA:1.10.150.390 1182 1240 8.5E-27 T 18-10-2018 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Pfam PF05000 RNA polymerase Rpb1, domain 4 750 804 8.8E-10 T 18-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_072 1d663690b7700c1e3a36b9146f5c932f 1286 Pfam PF04998 RNA polymerase Rpb1, domain 5 819 1181 2.8E-64 T 18-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 17 357 1.6E-126 T 18-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 PIRSF PIRSF004640 10 369 2.0E-142 T 18-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 15 366 33.337 T 18-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 SUPERFAMILY SSF56014 274 357 2.05E-12 T 18-10-2018 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 Gene3D G3DSA:3.20.20.20 9 270 7.1E-101 T 18-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 Pfam PF04551 GcpE protein 20 360 1.2E-129 T 18-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 SUPERFAMILY SSF51717 25 218 3.77E-9 T 18-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TWT_186 22c7e04d4b850484d7a7329a13e06595 380 Gene3D G3DSA:3.30.413.10 271 369 4.6E-36 T 18-10-2018 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:1.10.10.10 264 341 9.6E-29 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:3.40.50.300 25 187 1.3E-35 T 18-10-2018 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 240 4.7E-100 T 18-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 259 333 1.0E-36 T 18-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 SUPERFAMILY SSF46785 263 335 5.44E-22 T 18-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 30 333 5.1E-126 T 18-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:1.10.8.60 188 262 5.5E-23 T 18-10-2018 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 260 333 1.4E-28 T 18-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 345 141.364 T 18-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 SUPERFAMILY SSF52540 26 255 7.78E-48 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_269 29b0cb4be5d84db68deea143e8ddc122 345 SMART SM00382 57 190 3.7E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_026 37e7460c9393ca3992c7058b95599d32 484 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 92 464 33.536 T 18-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TWT_026 37e7460c9393ca3992c7058b95599d32 484 SUPERFAMILY SSF51246 413 479 8.63E-13 T 18-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TWT_026 37e7460c9393ca3992c7058b95599d32 484 Pfam PF02222 ATP-grasp domain 330 387 6.3E-20 T 18-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TWT_026 37e7460c9393ca3992c7058b95599d32 484 Pfam PF02222 ATP-grasp domain 197 300 2.2E-18 T 18-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TWT_026 37e7460c9393ca3992c7058b95599d32 484 SUPERFAMILY SSF52440 92 184 1.17E-18 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_026 37e7460c9393ca3992c7058b95599d32 484 Gene3D G3DSA:3.30.1490.20 192 255 4.2E-7 T 18-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TWT_026 37e7460c9393ca3992c7058b95599d32 484 Gene3D G3DSA:3.40.50.20 89 191 1.6E-25 T 18-10-2018 TWT_026 37e7460c9393ca3992c7058b95599d32 484 SUPERFAMILY SSF56059 187 408 4.42E-45 T 18-10-2018 TWT_600 883529108e5a72debe8a367c6c24475e 623 SUPERFAMILY SSF52540 367 613 1.5E-59 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_600 883529108e5a72debe8a367c6c24475e 623 SMART SM00382 401 588 2.8E-13 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_600 883529108e5a72debe8a367c6c24475e 623 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_600 883529108e5a72debe8a367c6c24475e 623 Gene3D G3DSA:3.40.50.300 371 621 4.9E-65 T 18-10-2018 TWT_600 883529108e5a72debe8a367c6c24475e 623 Pfam PF00664 ABC transporter transmembrane region 72 329 7.1E-22 T 18-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TWT_600 883529108e5a72debe8a367c6c24475e 623 Pfam PF00005 ABC transporter 393 542 8.0E-25 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_600 883529108e5a72debe8a367c6c24475e 623 SUPERFAMILY SSF90123 55 355 1.16E-41 T 18-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TWT_600 883529108e5a72debe8a367c6c24475e 623 Gene3D G3DSA:1.20.1560.10 48 357 2.2E-34 T 18-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TWT_216 39198fca009de0df095878e26d88cee0 601 SMART SM00740 469 535 1.7E-14 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 SMART SM00740 399 462 23.0 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 SMART SM00740 333 398 0.027 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 SMART SM00740 536 601 5.5E-8 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:1.10.510.10 98 287 5.7E-52 T 18-10-2018 TWT_216 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:3.30.10.20 474 537 2.2E-20 T 18-10-2018 TWT_216 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:3.30.10.20 336 401 1.3E-10 T 18-10-2018 TWT_216 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:3.30.10.20 538 599 6.8E-11 T 18-10-2018 TWT_216 39198fca009de0df095878e26d88cee0 601 SUPERFAMILY SSF56112 12 273 1.62E-75 T 18-10-2018 IPR011009 Protein kinase-like domain superfamily TWT_216 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 337 397 9.4E-8 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 540 599 1.1E-9 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 475 535 3.5E-14 T 18-10-2018 IPR005543 PASTA domain TWT_216 39198fca009de0df095878e26d88cee0 601 SMART SM00220 16 272 1.2E-59 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_216 39198fca009de0df095878e26d88cee0 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 18-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TWT_216 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:3.30.200.20 4 95 3.4E-25 T 18-10-2018 TWT_216 39198fca009de0df095878e26d88cee0 601 Pfam PF00069 Protein kinase domain 18 266 6.0E-52 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 13 115 19.692 T 18-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 17 102 9.0E-44 T 18-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 SUPERFAMILY SSF89919 9 118 7.46E-22 T 18-10-2018 IPR023799 Ribosome-binding factor A domain superfamily TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 Gene3D G3DSA:3.30.300.20 10 123 1.4E-21 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 9 117 2.2E-17 T 18-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TWT_159 430fdc55af904ab63d0825c6ff9db30d 196 Pfam PF02033 Ribosome-binding factor A 14 115 1.3E-20 T 18-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TWT_751 a4d402569911d29f95dfbc666afe133d 170 SUPERFAMILY SSF53927 11 167 6.86E-49 T 18-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TWT_751 a4d402569911d29f95dfbc666afe133d 170 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 74 111 - T 18-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TWT_751 a4d402569911d29f95dfbc666afe133d 170 Gene3D G3DSA:3.40.140.10 13 170 2.3E-54 T 18-10-2018 TWT_751 a4d402569911d29f95dfbc666afe133d 170 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 28 170 40.726 T 18-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TWT_751 a4d402569911d29f95dfbc666afe133d 170 Pfam PF14437 MafB19-like deaminase 24 170 5.4E-32 T 18-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 856 5.4E-225 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:3.30.54.20 608 662 4.4E-33 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 637 681 1.3E-12 T 18-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:2.40.30.130 445 534 3.1E-7 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:3.10.310.40 774 875 1.2E-11 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF55186 536 696 9.03E-38 T 18-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Pfam PF01411 tRNA synthetases class II (A) 6 538 4.1E-171 T 18-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF101353 234 430 2.09E-52 T 18-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 214 227 1.1E-26 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.1E-26 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 186 197 1.1E-26 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 264 280 1.1E-26 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 288 301 1.1E-26 T 18-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 134.204 T 18-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 SMART SM00863 637 681 1.5E-15 T 18-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:3.30.980.10 547 682 4.4E-33 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Pfam PF02272 DHHA1 domain 776 871 1.9E-7 T 18-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:3.30.930.10 1 229 1.9E-86 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF55681 3 233 7.7E-82 T 18-10-2018 TWT_376 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF50447 438 536 1.55E-12 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_237 56f4a7e4c66613a707edc9d2b1ff1bec 147 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 147 70.861 T 18-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TWT_237 56f4a7e4c66613a707edc9d2b1ff1bec 147 Pfam PF03477 ATP cone domain 47 132 1.2E-15 T 18-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TWT_237 56f4a7e4c66613a707edc9d2b1ff1bec 147 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 7.6E-47 T 18-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TWT_102 c6de8fe16da26130710394795fde235b 545 PIRSF PIRSF003128 1 540 1.6E-129 T 18-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TWT_102 c6de8fe16da26130710394795fde235b 545 SUPERFAMILY SSF52540 1 502 1.0E-51 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_102 c6de8fe16da26130710394795fde235b 545 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 494 5.5E-19 T 18-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TWT_102 c6de8fe16da26130710394795fde235b 545 Gene3D G3DSA:3.40.50.300 1 251 1.6E-32 T 18-10-2018 TWT_102 c6de8fe16da26130710394795fde235b 545 Gene3D G3DSA:3.40.50.300 252 536 7.5E-45 T 18-10-2018 TWT_102 c6de8fe16da26130710394795fde235b 545 SMART SM00382 21 496 0.001 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_477 ff065d8be39054307721e4faa22b9d37 1066 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 33 876 1.8E-237 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 SUPERFAMILY SSF52374 32 673 1.07E-124 T 18-10-2018 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Gene3D G3DSA:3.40.50.620 40 668 1.3E-214 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 27 1051 13.319 T 18-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 SUPERFAMILY SSF50677 231 434 2.35E-42 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 SUPERFAMILY SSF47323 696 915 4.11E-38 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 43 676 2.1E-170 T 18-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Pfam PF08264 Anticodon-binding domain of tRNA 730 870 4.4E-25 T 18-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Gene3D G3DSA:3.90.740.10 222 438 1.3E-214 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 432 447 1.3E-28 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 574 1.3E-28 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 601 610 1.3E-28 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 66 77 1.3E-28 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 256 279 1.3E-28 T 18-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 SUPERFAMILY SSF47323 979 1053 3.6E-5 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_477 ff065d8be39054307721e4faa22b9d37 1066 Gene3D G3DSA:1.10.730.10 683 863 3.5E-38 T 18-10-2018 TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 153 24.501 T 18-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 Pfam PF01281 Ribosomal protein L9, N-terminal domain 4 47 3.2E-19 T 18-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 18-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 Gene3D G3DSA:3.40.5.10 2 62 9.9E-19 T 18-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 SUPERFAMILY SSF55653 58 153 4.84E-24 T 18-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 SUPERFAMILY SSF55658 3 57 4.53E-16 T 18-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 151 9.2E-27 T 18-10-2018 IPR020069 Ribosomal protein L9, C-terminal TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 Gene3D G3DSA:3.10.430.100 63 153 1.6E-26 T 18-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TWT_105 e34f5a1a482c8da8f0ed794151e8d883 153 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 153 5.2E-36 T 18-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 SUPERFAMILY SSF90123 28 335 3.01E-34 T 18-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 Gene3D G3DSA:3.40.50.300 346 589 5.9E-78 T 18-10-2018 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 Gene3D G3DSA:1.20.1560.10 27 333 1.6E-25 T 18-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 Pfam PF00005 ABC transporter 369 516 1.0E-30 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 Pfam PF00664 ABC transporter transmembrane region 38 291 6.8E-9 T 18-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 SUPERFAMILY SSF52540 347 581 1.07E-72 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 SMART SM00382 378 563 2.0E-15 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_601 2cd752e28a62bdfcb1a42fe76b540863 589 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 Pfam PF00677 Lumazine binding domain 121 220 1.6E-23 T 18-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 Pfam PF00677 Lumazine binding domain 3 107 5.5E-14 T 18-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 SUPERFAMILY SSF63380 115 231 2.17E-26 T 18-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TWT_688 a04c9b0621e99be9e5db47995580cec9 237 Gene3D G3DSA:2.40.30.20 1 109 3.3E-15 T 18-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 Gene3D G3DSA:2.40.30.20 123 236 1.1E-25 T 18-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 SUPERFAMILY SSF63380 34 109 7.57E-17 T 18-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TWT_688 a04c9b0621e99be9e5db47995580cec9 237 PIRSF PIRSF000498 1 48 1.8 T 18-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_688 a04c9b0621e99be9e5db47995580cec9 237 PIRSF PIRSF000498 29 236 5.1E-53 T 18-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_266 bbfb61f56800449f61c688029d867c2e 252 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 246 31.07 T 18-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 SUPERFAMILY SSF75625 3 245 2.22E-77 T 18-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:3.30.70.980 131 212 7.7E-44 T 18-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 Pfam PF01709 Transcriptional regulator 5 244 4.8E-79 T 18-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:3.30.70.980 87 243 7.7E-44 T 18-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 244 8.8E-80 T 18-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_266 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:1.10.10.200 1 80 7.3E-32 T 18-10-2018 IPR017856 Integrase-like, N-terminal TWT_429 7c61eff8a0496323861745573f7c31c0 75 Gene3D G3DSA:1.20.20.10 3 75 3.2E-21 T 18-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_429 7c61eff8a0496323861745573f7c31c0 75 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 14.952 T 18-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_429 7c61eff8a0496323861745573f7c31c0 75 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 72 1.1E-18 T 18-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TWT_429 7c61eff8a0496323861745573f7c31c0 75 Pfam PF00137 ATP synthase subunit C 13 72 1.4E-11 T 18-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TWT_429 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 50 75 9.0E-14 T 18-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_429 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 12 31 9.0E-14 T 18-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_429 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 33 48 9.0E-14 T 18-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_429 7c61eff8a0496323861745573f7c31c0 75 SUPERFAMILY SSF81333 13 74 5.89E-17 T 18-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TWT_429 7c61eff8a0496323861745573f7c31c0 75 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 18-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF56059 679 953 3.54E-90 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 5 1074 0.0 T 18-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 844 851 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 435 549 1.2E-36 T 18-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:3.30.470.20 671 955 2.4E-96 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF56059 128 400 3.01E-102 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SMART SM01096 431 549 2.5E-60 T 18-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF52440 560 681 5.18E-43 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:3.30.470.20 119 402 1.5E-114 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF48108 395 556 7.45E-47 T 18-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:1.10.1030.10 418 555 3.3E-41 T 18-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:3.40.50.20 557 668 6.6E-44 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 334 3.9E-65 T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 880 2.2E-32 T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 715 729 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF52440 1 126 9.35E-46 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:3.40.50.1380 956 1093 7.3E-36 T 18-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.397 T 18-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Gene3D G3DSA:3.40.50.20 1 116 6.8E-45 T 18-10-2018 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 9.0E-62 T 18-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SMART SM00851 975 1065 1.6E-21 T 18-10-2018 IPR011607 Methylglyoxal synthase-like domain TWT_365 b8a6d99ffa53764748df383adeea873a 1103 Pfam PF02142 MGS-like domain 977 1065 1.8E-15 T 18-10-2018 IPR011607 Methylglyoxal synthase-like domain TWT_365 b8a6d99ffa53764748df383adeea873a 1103 SUPERFAMILY SSF52335 957 1092 1.7E-28 T 18-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TWT_679 562b41b48d3efa779701c25c3fc17596 121 Pfam PF14155 Domain of unknown function (DUF4307) 18 115 2.6E-11 T 18-10-2018 IPR025443 Protein of unknown function DUF4307 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Gene3D G3DSA:1.20.120.140 8 296 4.0E-91 T 18-10-2018 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SMART SM00962 102 294 3.1E-77 T 18-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SUPERFAMILY SSF52540 101 295 9.88E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Gene3D G3DSA:3.40.50.300 92 283 4.0E-91 T 18-10-2018 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Pfam PF02978 Signal peptide binding domain 320 410 4.2E-20 T 18-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SUPERFAMILY SSF47364 2 94 1.47E-17 T 18-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SMART SM00963 3 88 2.7E-18 T 18-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Pfam PF00448 SRP54-type protein, GTPase domain 102 294 8.4E-58 T 18-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Gene3D G3DSA:1.10.260.30 319 435 2.1E-24 T 18-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SUPERFAMILY SSF47446 302 411 5.49E-23 T 18-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 Pfam PF02881 SRP54-type protein, helical bundle domain 8 84 4.0E-12 T 18-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_462 3aa1506bc1e3c13f6a4418a6b4cc2b95 448 SMART SM00382 101 260 1.4E-5 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Gene3D G3DSA:2.60.40.10 1511 1602 2.1E-5 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 SUPERFAMILY SSF49313 533 622 4.32E-7 T 18-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 868 932 4.8E-15 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1121 1160 4.5E-10 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1905 1960 1.6E-5 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1212 1263 1.2E-10 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 2014 2058 1.8E-7 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 995 1053 2.1E-13 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 553 606 1.0E-11 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1540 1591 1.6E-9 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 322 381 3.1E-12 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1733 1779 6.4E-7 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1424 1488 7.9E-8 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 657 724 1.0E-11 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1319 1372 1.6E-10 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF05345 Putative Ig domain 1635 1685 1.8E-10 T 18-10-2018 IPR008009 Putative Ig TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 SUPERFAMILY SSF49313 1212 1277 5.18E-6 T 18-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Gene3D G3DSA:2.60.40.10 525 624 7.3E-8 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Gene3D G3DSA:2.60.40.10 966 1063 5.5E-9 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Gene3D G3DSA:2.60.40.10 292 391 1.0E-5 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_104 fe39d49460005cdfb9272fc1f5df52d9 2312 Pfam PF07860 WisP family C-Terminal Region 2075 2204 1.4E-88 T 18-10-2018 IPR012421 WisP, C-terminal TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 Gene3D G3DSA:3.30.70.250 160 223 6.2E-59 T 18-10-2018 TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 SUPERFAMILY SSF52151 19 333 1.44E-47 T 18-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 Pfam PF00698 Acyl transferase domain 120 239 2.5E-8 T 18-10-2018 IPR014043 Acyl transferase TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 SUPERFAMILY SSF55048 162 212 7.59E-11 T 18-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 21 322 1.8E-10 T 18-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TWT_254 fdd6a51e2eb68d235d3543ed8f84a991 339 Gene3D G3DSA:3.40.366.10 21 314 6.2E-59 T 18-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Pfam PF00308 Bacterial dnaA protein 144 360 2.8E-91 T 18-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:1.10.8.60 309 378 6.3E-23 T 18-10-2018 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SMART SM00382 175 327 5.7E-6 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 11 473 5.0E-148 T 18-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 ProSitePatterns PS01008 DnaA protein signature. 436 454 - T 18-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SUPERFAMILY SSF48295 373 475 7.32E-30 T 18-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SMART SM00760 386 454 8.4E-34 T 18-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 389 454 1.3E-24 T 18-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 8 476 29.054 T 18-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 4.5E-44 T 18-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 4.5E-44 T 18-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 240 254 4.5E-44 T 18-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 274 301 4.5E-44 T 18-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 435 454 4.5E-44 T 18-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SUPERFAMILY SSF52540 144 354 1.68E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:1.10.1750.10 382 478 8.4E-28 T 18-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TWT_001 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:3.40.50.300 133 307 3.9E-47 T 18-10-2018 TWT_695 26c4ab208972b587e829b2a73fbd6d28 199 Pfam PF02223 Thymidylate kinase 5 185 1.9E-38 T 18-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TWT_695 26c4ab208972b587e829b2a73fbd6d28 199 Gene3D G3DSA:3.40.50.300 1 194 2.6E-54 T 18-10-2018 TWT_695 26c4ab208972b587e829b2a73fbd6d28 199 SUPERFAMILY SSF52540 1 194 7.72E-41 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_695 26c4ab208972b587e829b2a73fbd6d28 199 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 185 8.3E-41 T 18-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TWT_695 26c4ab208972b587e829b2a73fbd6d28 199 Hamap MF_00165 Thymidylate kinase [tmk]. 1 193 26.234 T 18-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TWT_693 623356dc5715cc0aff71f9353f90773c 512 Pfam PF00561 alpha/beta hydrolase fold 99 282 7.3E-18 T 18-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TWT_693 623356dc5715cc0aff71f9353f90773c 512 SUPERFAMILY SSF53474 93 474 2.41E-24 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_693 623356dc5715cc0aff71f9353f90773c 512 Pfam PF08386 TAP-like protein 405 506 7.8E-28 T 18-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 PIRSF PIRSF001586 1 225 4.6E-75 T 18-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 220 35.546 T 18-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 SUPERFAMILY SSF52317 3 202 1.39E-59 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 219 8.0E-73 T 18-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 SMART SM01211 2 222 5.2E-92 T 18-10-2018 TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 1.3E-31 T 18-10-2018 TWT_795 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Gene3D G3DSA:3.40.50.880 2 223 8.2E-55 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Gene3D G3DSA:3.30.300.10 100 382 9.9E-149 T 18-10-2018 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 3 383 2.4E-149 T 18-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Gene3D G3DSA:3.30.300.10 8 282 9.9E-149 T 18-10-2018 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Gene3D G3DSA:3.30.300.10 3 245 9.9E-149 T 18-10-2018 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 PIRSF PIRSF000497 1 394 1.5E-156 T 18-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 SUPERFAMILY SSF55973 2 106 5.49E-36 T 18-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 2 97 1.2E-32 T 18-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 395 46.99 T 18-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 18-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 SUPERFAMILY SSF55973 246 384 3.73E-59 T 18-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 SUPERFAMILY SSF55973 122 244 1.68E-40 T 18-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 246 382 7.7E-61 T 18-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_360 cb2528adc42133ffb27c30ce07f1ec96 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 243 3.2E-38 T 18-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 473 4.1E-143 T 18-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:1.10.268.10 371 459 6.7E-186 T 18-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 508 548 4.8E-11 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 557 606 3.7E-8 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 713 760 2.8E-8 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 3.7E-9 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 770 808 2.3E-5 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 614 656 5.1E-10 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 6 809 0.0 T 18-10-2018 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:3.90.199.10 30 488 6.7E-186 T 18-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 811 22.44 T 18-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SUPERFAMILY SSF101904 501 815 2.22E-94 T 18-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:3.30.1360.40 238 334 6.7E-186 T 18-10-2018 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:2.120.10.90 498 809 1.4E-105 T 18-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SMART SM00434 9 466 4.6E-250 T 18-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_006 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SUPERFAMILY SSF56719 29 489 7.98E-161 T 18-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 83 94 - T 18-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 SUPERFAMILY SSF54686 2 138 5.63E-53 T 18-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 60 71 - T 18-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 Pfam PF00252 Ribosomal protein L16p/L10e 5 133 8.7E-46 T 18-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 2 135 38.353 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 PRINTS PR00060 Ribosomal protein L16 signature 89 118 1.1E-39 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 PRINTS PR00060 Ribosomal protein L16 signature 25 37 1.1E-39 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 PRINTS PR00060 Ribosomal protein L16 signature 59 88 1.1E-39 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 PRINTS PR00060 Ribosomal protein L16 signature 43 54 1.1E-39 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 Gene3D G3DSA:3.90.1170.10 2 143 5.4E-49 T 18-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_547 64b129d7193fbefa7cc6bd579c08d924 143 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 3 127 2.4E-54 T 18-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 Pfam PF11967 Recombination protein O N terminal 25 100 6.4E-24 T 18-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 Hamap MF_00201 DNA repair protein RecO [recO]. 23 260 22.669 T 18-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 Pfam PF02565 Recombination protein O C terminal 111 254 9.5E-16 T 18-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 Gene3D G3DSA:2.40.50.140 22 104 2.3E-20 T 18-10-2018 TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 TIGRFAM TIGR00613 reco: DNA repair protein RecO 26 257 1.1E-30 T 18-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 SUPERFAMILY SSF57863 104 249 1.57E-24 T 18-10-2018 IPR037278 ARFGAP/RecO-like zinc finger TWT_285 198b9abd4554045f57fb91dbe2dbaef2 261 SUPERFAMILY SSF50249 24 100 1.71E-17 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 Pfam PF02381 MraZ protein, putative antitoxin-like 71 136 3.7E-16 T 18-10-2018 IPR020603 MraZ domain TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 69 7.7E-12 T 18-10-2018 IPR020603 MraZ domain TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 42.278 T 18-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 137 1.5E-35 T 18-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 SUPERFAMILY SSF89447 2 135 1.28E-38 T 18-10-2018 IPR037914 SpoVT-AbrB domain superfamily TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 137 1.0E-75 T 18-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TWT_219 3256c3cc8fddd1e8f598cac4e7795ca8 142 Gene3D G3DSA:2.40.330.20 1 139 8.3E-41 T 18-10-2018 IPR038619 MraZ superfamily TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 150 3.5E-21 T 18-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF56553 48 170 1.16E-39 T 18-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 312 33.462 T 18-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF55257 13 221 1.81E-23 T 18-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:3.30.1360.10 13 218 2.6E-78 T 18-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:1.10.150.20 221 317 1.0E-27 T 18-10-2018 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 317 4.0E-32 T 18-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF47789 248 319 1.09E-23 T 18-10-2018 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.9E-18 T 18-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.1E-106 T 18-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 304 6.5E-26 T 18-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 SMART SM00662 18 226 9.0E-73 T 18-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_528 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:2.170.120.12 48 169 2.6E-78 T 18-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Gene3D G3DSA:2.60.260.20 94 226 1.2E-28 T 18-10-2018 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Pfam PF00226 DnaJ domain 3 62 2.3E-22 T 18-10-2018 IPR001623 DnaJ domain TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Gene3D G3DSA:1.10.287.110 1 93 5.5E-25 T 18-10-2018 IPR036869 Chaperone J-domain superfamily TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 PRINTS PR00625 DnaJ domain signature 23 38 6.3E-11 T 18-10-2018 IPR001623 DnaJ domain TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 PRINTS PR00625 DnaJ domain signature 5 23 6.3E-11 T 18-10-2018 IPR001623 DnaJ domain TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 PRINTS PR00625 DnaJ domain signature 57 76 6.3E-11 T 18-10-2018 IPR001623 DnaJ domain TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Gene3D G3DSA:2.60.260.20 231 330 6.1E-24 T 18-10-2018 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 346 32.343 T 18-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Pfam PF00684 DnaJ central domain 122 186 1.9E-11 T 18-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Gene3D G3DSA:2.10.230.10 122 186 1.2E-28 T 18-10-2018 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 SUPERFAMILY SSF46565 2 83 3.53E-27 T 18-10-2018 IPR036869 Chaperone J-domain superfamily TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 SUPERFAMILY SSF57938 111 187 6.28E-15 T 18-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 SUPERFAMILY SSF49493 236 320 1.03E-16 T 18-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 ProSitePatterns PS00636 Nt-dnaJ domain signature. 42 61 - T 18-10-2018 IPR018253 DnaJ domain, conserved site TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 SUPERFAMILY SSF49493 90 244 7.19E-16 T 18-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 Pfam PF01556 DnaJ C terminal domain 187 306 6.6E-30 T 18-10-2018 IPR002939 Chaperone DnaJ, C-terminal TWT_280 f5de21cd9e312c57f3e1f51d416ab957 348 SMART SM00271 2 57 2.4E-24 T 18-10-2018 IPR001623 DnaJ domain TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Gene3D G3DSA:1.10.150.20 93 162 1.1E-20 T 18-10-2018 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 29 219 25.936 T 18-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 SMART SM00278 98 117 0.8 T 18-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 SMART SM00278 133 152 160.0 T 18-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Pfam PF14520 Helix-hairpin-helix domain 97 153 2.5E-13 T 18-10-2018 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 SUPERFAMILY SSF50249 29 88 2.63E-11 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Pfam PF01330 RuvA N terminal domain 30 87 4.0E-15 T 18-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Gene3D G3DSA:1.10.8.10 174 221 3.1E-15 T 18-10-2018 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 SUPERFAMILY SSF46929 174 220 1.57E-9 T 18-10-2018 IPR036267 RuvA, C-terminal domain superfamily TWT_268 2205c35d5ff0707c3d8c97543893924a 222 SUPERFAMILY SSF47781 92 161 1.92E-17 T 18-10-2018 IPR010994 RuvA domain 2-like TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Pfam PF07499 RuvA, C-terminal domain 173 218 6.3E-11 T 18-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 Gene3D G3DSA:2.40.50.140 29 91 4.4E-16 T 18-10-2018 TWT_268 2205c35d5ff0707c3d8c97543893924a 222 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 29 217 3.5E-38 T 18-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TWT_168 e936a296f8b4282b945488ede58aa787 962 SMART SM00873 270 442 3.7E-68 T 18-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 Pfam PF03147 Ferredoxin-fold anticodon binding domain 871 961 1.9E-18 T 18-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 SMART SM00896 870 961 7.7E-27 T 18-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 Gene3D G3DSA:3.50.40.10 263 450 3.1E-64 T 18-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 SMART SM00874 458 533 6.0E-15 T 18-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TWT_168 e936a296f8b4282b945488ede58aa787 962 SUPERFAMILY SSF50249 123 250 4.57E-17 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_168 e936a296f8b4282b945488ede58aa787 962 SUPERFAMILY SSF56037 265 447 8.37E-61 T 18-10-2018 TWT_168 e936a296f8b4282b945488ede58aa787 962 Pfam PF01588 Putative tRNA binding domain 128 191 5.0E-5 T 18-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TWT_168 e936a296f8b4282b945488ede58aa787 962 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 4 955 39.498 T 18-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 Pfam PF03484 tRNA synthetase B5 domain 465 533 2.2E-13 T 18-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TWT_168 e936a296f8b4282b945488ede58aa787 962 Pfam PF03483 B3/4 domain 273 441 5.8E-57 T 18-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 SUPERFAMILY SSF46955 461 537 1.65E-12 T 18-10-2018 IPR009061 Putative DNA-binding domain superfamily TWT_168 e936a296f8b4282b945488ede58aa787 962 Gene3D G3DSA:3.30.70.380 872 962 1.0E-15 T 18-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 SUPERFAMILY SSF54991 866 961 7.45E-20 T 18-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TWT_168 e936a296f8b4282b945488ede58aa787 962 SUPERFAMILY SSF55681 675 858 2.48E-29 T 18-10-2018 TWT_168 e936a296f8b4282b945488ede58aa787 962 Gene3D G3DSA:3.30.56.10 459 537 3.1E-15 T 18-10-2018 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 194 255 1.1E-17 T 18-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 Gene3D G3DSA:1.10.3090.10 170 468 1.9E-44 T 18-10-2018 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 Pfam PF01743 Poly A polymerase head domain 45 166 3.3E-29 T 18-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 SMART SM00471 265 407 8.8E-8 T 18-10-2018 IPR003607 HD/PDEase domain TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 TIGRFAM TIGR00277 HDIG: HDIG domain 266 343 1.8E-15 T 18-10-2018 IPR006675 HDIG domain TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 16 480 3.3E-233 T 18-10-2018 IPR014065 tRNA adenylyltransferase TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 SUPERFAMILY SSF81301 20 164 9.26E-37 T 18-10-2018 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 SUPERFAMILY SSF81891 166 480 8.37E-60 T 18-10-2018 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 Gene3D G3DSA:3.30.460.10 14 164 2.2E-36 T 18-10-2018 TWT_800 c9fb901f46ded7811c503b3332fa32b0 484 Pfam PF01966 HD domain 269 397 2.0E-13 T 18-10-2018 IPR006674 HD domain TWT_413 2c9aa7f19c7c4dfb0f42296fe75f9504 100 SUPERFAMILY SSF141000 2 90 1.96E-8 T 18-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TWT_413 2c9aa7f19c7c4dfb0f42296fe75f9504 100 Gene3D G3DSA:1.10.20.60 2 39 1.3E-6 T 18-10-2018 TWT_456 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 36 52 1.2E-21 T 18-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TWT_456 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 113 125 1.2E-21 T 18-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TWT_456 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 163 182 1.2E-21 T 18-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TWT_456 95ca937c3c90256799f90d5b33c845dc 230 Pfam PF00717 Peptidase S24-like 42 137 1.2E-13 T 18-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TWT_456 95ca937c3c90256799f90d5b33c845dc 230 SUPERFAMILY SSF51306 34 215 1.88E-48 T 18-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TWT_456 95ca937c3c90256799f90d5b33c845dc 230 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 21 209 1.2E-39 T 18-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TWT_456 95ca937c3c90256799f90d5b33c845dc 230 ProSitePatterns PS00761 Signal peptidases I signature 3. 168 181 - T 18-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 TWT_535 e68c08a407cf91478c4d01080a714517 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 439 27.812 T 18-10-2018 IPR026593 Protein translocase subunit SecY TWT_535 e68c08a407cf91478c4d01080a714517 441 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 18-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 SUPERFAMILY SSF103491 4 430 8.37E-115 T 18-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 Pfam PF00344 SecY translocase 73 423 9.2E-109 T 18-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 PIRSF PIRSF004557 2 440 2.5E-111 T 18-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 435 5.9E-124 T 18-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 408 426 6.1E-98 T 18-10-2018 TWT_535 e68c08a407cf91478c4d01080a714517 441 Gene3D G3DSA:1.10.3370.10 1 435 4.4E-148 T 18-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_535 e68c08a407cf91478c4d01080a714517 441 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 18-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 Gene3D G3DSA:3.40.50.1260 176 387 3.0E-131 T 18-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 Gene3D G3DSA:3.40.50.1260 14 395 3.0E-131 T 18-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 SUPERFAMILY SSF53748 14 395 2.12E-124 T 18-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 Pfam PF00162 Phosphoglycerate kinase 14 387 5.9E-128 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 9 25 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 111 126 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 4.1E-75 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 395 36.292 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_301 fa3e4928b9d3e409a73e5677ae1dadd7 395 PIRSF PIRSF000724 3 395 1.2E-129 T 18-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_801 3fea6550bccfbdd80fa612771efd3282 298 SUPERFAMILY SSF110849 42 133 1.02E-27 T 18-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TWT_801 3fea6550bccfbdd80fa612771efd3282 298 SMART SM00470 42 131 7.6E-32 T 18-10-2018 IPR003115 ParB/Sulfiredoxin TWT_801 3fea6550bccfbdd80fa612771efd3282 298 Gene3D G3DSA:1.10.10.2830 119 231 2.6E-35 T 18-10-2018 TWT_801 3fea6550bccfbdd80fa612771efd3282 298 SUPERFAMILY SSF109709 124 231 1.05E-31 T 18-10-2018 TWT_801 3fea6550bccfbdd80fa612771efd3282 298 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 216 5.2E-57 T 18-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TWT_801 3fea6550bccfbdd80fa612771efd3282 298 Pfam PF02195 ParB-like nuclease domain 44 131 1.1E-23 T 18-10-2018 IPR003115 ParB/Sulfiredoxin TWT_801 3fea6550bccfbdd80fa612771efd3282 298 Gene3D G3DSA:3.90.1530.30 55 117 1.8E-25 T 18-10-2018 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 18-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 Pfam PF04055 Radical SAM superfamily 147 319 6.7E-27 T 18-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 SMART SM00729 143 362 1.8E-54 T 18-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 439 63.858 T 18-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 Gene3D G3DSA:3.40.50.12160 1 130 2.7E-33 T 18-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 Gene3D G3DSA:3.80.30.20 140 375 6.9E-88 T 18-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 3 434 2.0E-133 T 18-10-2018 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 435 2.5E-147 T 18-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 SUPERFAMILY SSF102114 128 366 2.88E-57 T 18-10-2018 TWT_610 88352507f37b22aa1b59d46d36b68cfb 470 Pfam PF00919 Uncharacterized protein family UPF0004 3 100 4.1E-27 T 18-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 SUPERFAMILY SSF54843 3 115 1.83E-33 T 18-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 Pfam PF00237 Ribosomal protein L22p/L17e 14 114 4.7E-26 T 18-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 Gene3D G3DSA:3.90.470.10 9 119 6.4E-36 T 18-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 9 117 24.589 T 18-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 ProSitePatterns PS00464 Ribosomal protein L22 signature. 90 114 - T 18-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_549 df41e6f20e1737e41196f7eb451169fb 119 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 13 113 1.4E-30 T 18-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 SMART SM00434 24 477 3.5E-207 T 18-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Gene3D G3DSA:3.30.1360.40 248 345 3.8E-183 T 18-10-2018 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 45 484 4.7E-145 T 18-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Gene3D G3DSA:2.120.10.90 516 802 4.2E-30 T 18-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 SUPERFAMILY SSF56719 44 498 5.1E-154 T 18-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 SUPERFAMILY SSF101904 511 788 7.59E-29 T 18-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 665 707 4.3E-6 T 18-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Gene3D G3DSA:3.90.199.10 45 497 3.8E-183 T 18-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TWT_491 5609b06d2c67e517c8cad5aeba785dd4 824 Gene3D G3DSA:1.10.268.10 382 470 3.8E-183 T 18-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 SMART SM00878 337 443 5.1E-53 T 18-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF51246 332 448 1.88E-38 T 18-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:3.30.470.130 1 451 2.4E-173 T 18-10-2018 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 545 562 - T 18-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 1.5E-41 T 18-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 6.4E-37 T 18-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF52440 2 115 1.65E-44 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:2.40.50.100 511 587 1.1E-22 T 18-10-2018 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF51230 510 588 8.51E-21 T 18-10-2018 IPR011053 Single hybrid motif TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF00364 Biotin-requiring enzyme 525 588 3.4E-16 T 18-10-2018 IPR000089 Biotin/lipoyl attachment TWT_020 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 325 3.1E-72 T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_020 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF56059 117 326 2.47E-56 T 18-10-2018 TWT_465 823bba19c8d7010bba290f2f4f6d1321 184 Gene3D G3DSA:1.10.10.10 102 184 4.1E-25 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_465 823bba19c8d7010bba290f2f4f6d1321 184 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 149 155 - T 18-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TWT_465 823bba19c8d7010bba290f2f4f6d1321 184 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 104 180 1.2E-22 T 18-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TWT_465 823bba19c8d7010bba290f2f4f6d1321 184 SUPERFAMILY SSF46767 103 181 5.76E-22 T 18-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TWT_465 823bba19c8d7010bba290f2f4f6d1321 184 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 104 180 3.7E-22 T 18-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TWT_761 f578a0721c972eb7e0658e2dbf6b426a 104 SUPERFAMILY SSF81345 13 81 2.48E-9 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_761 f578a0721c972eb7e0658e2dbf6b426a 104 Pfam PF00950 ABC 3 transport family 13 83 3.7E-17 T 18-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Pfam PF03129 Anticodon binding domain 532 616 5.6E-12 T 18-10-2018 IPR004154 Anticodon-binding TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Gene3D G3DSA:3.30.54.20 108 167 5.0E-54 T 18-10-2018 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 50 617 6.7E-181 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Gene3D G3DSA:3.30.930.10 207 523 3.4E-106 T 18-10-2018 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 455 483 1.5E-51 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 525 537 1.5E-51 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 351 374 1.5E-51 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 318 346 1.5E-51 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 498 511 1.5E-51 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 44 625 30.607 T 18-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 SUPERFAMILY SSF55186 41 220 1.7E-51 T 18-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 SMART SM00863 143 200 1.9E-18 T 18-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 315 520 6.6E-36 T 18-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Gene3D G3DSA:3.30.980.10 47 203 5.0E-54 T 18-10-2018 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Gene3D G3DSA:3.40.50.800 524 637 7.5E-20 T 18-10-2018 IPR036621 Anticodon-binding domain superfamily TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 157 200 1.5E-11 T 18-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 SUPERFAMILY SSF52954 520 624 2.87E-22 T 18-10-2018 TWT_262 fac1b8a43da7fce6003cd21b1c6c5b59 640 SUPERFAMILY SSF55681 224 516 2.81E-82 T 18-10-2018 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 SUPERFAMILY SSF54814 2 110 3.4E-34 T 18-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 Pfam PF07650 KH domain 42 114 4.2E-19 T 18-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 210 6.5E-85 T 18-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 206 5.8E-33 T 18-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 SMART SM00322 64 129 8.6E-5 T 18-10-2018 IPR004087 K Homology domain GO:0003676 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 215 36.352 T 18-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 Gene3D G3DSA:3.30.1140.32 112 211 7.4E-36 T 18-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 Gene3D G3DSA:3.30.300.20 18 111 1.2E-27 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_548 da5b24dfa6650b66f99639f602c81b23 220 SUPERFAMILY SSF54821 111 209 2.09E-33 T 18-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_548 da5b24dfa6650b66f99639f602c81b23 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 167 201 - T 18-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 Gene3D G3DSA:2.40.240.20 2 71 2.4E-10 T 18-10-2018 TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 PIRSF PIRSF015601 1 235 2.5E-53 T 18-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 SUPERFAMILY SSF88697 4 59 2.73E-5 T 18-10-2018 IPR015947 PUA-like superfamily TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 Gene3D G3DSA:3.40.1280.10 75 235 1.2E-35 T 18-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 Pfam PF04452 RNA methyltransferase 19 229 3.6E-48 T 18-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 SUPERFAMILY SSF75217 77 235 9.16E-33 T 18-10-2018 IPR029028 Alpha/beta knot methyltransferases TWT_281 1dce37dbb5ffd951e72903693ae6ce6b 235 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 15 233 3.1E-28 T 18-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TWT_621 d6a19cf66d565f9bd0b51d7cd26fec42 193 SUPERFAMILY SSF52972 1 185 1.31E-55 T 18-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TWT_621 d6a19cf66d565f9bd0b51d7cd26fec42 193 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 184 3.8E-47 T 18-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TWT_621 d6a19cf66d565f9bd0b51d7cd26fec42 193 Pfam PF01725 Ham1 family 3 180 2.4E-49 T 18-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TWT_621 d6a19cf66d565f9bd0b51d7cd26fec42 193 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 186 44.535 T 18-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TWT_621 d6a19cf66d565f9bd0b51d7cd26fec42 193 Gene3D G3DSA:3.90.950.10 1 190 5.2E-57 T 18-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 PIRSF PIRSF000362 1 443 2.4E-152 T 18-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 SUPERFAMILY SSF51971 3 290 4.3E-50 T 18-10-2018 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 3.8E-15 T 18-10-2018 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 3.8E-15 T 18-10-2018 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 142 156 3.8E-15 T 18-10-2018 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 SUPERFAMILY SSF51971 299 436 6.47E-6 T 18-10-2018 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 164 1.6E-6 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 Gene3D G3DSA:3.50.50.60 45 320 1.4E-129 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_055 bb37d04ac174070c192e5a3acb20a88f 447 Gene3D G3DSA:3.40.50.720 4 437 1.4E-129 T 18-10-2018 TWT_614 4132a3835e68dc63f3a90db98879a08e 741 Pfam PF09397 Ftsk gamma domain 662 720 1.7E-22 T 18-10-2018 IPR018541 FtsK gamma domain TWT_614 4132a3835e68dc63f3a90db98879a08e 741 Gene3D G3DSA:3.30.980.40 260 362 1.9E-27 T 18-10-2018 TWT_614 4132a3835e68dc63f3a90db98879a08e 741 Pfam PF01580 FtsK/SpoIIIE family 373 561 1.8E-55 T 18-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TWT_614 4132a3835e68dc63f3a90db98879a08e 741 SMART SM00843 657 722 4.8E-29 T 18-10-2018 IPR018541 FtsK gamma domain TWT_614 4132a3835e68dc63f3a90db98879a08e 741 SUPERFAMILY SSF46785 658 724 2.04E-17 T 18-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TWT_614 4132a3835e68dc63f3a90db98879a08e 741 SMART SM00382 399 594 0.0027 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_614 4132a3835e68dc63f3a90db98879a08e 741 Gene3D G3DSA:1.10.10.10 654 718 2.7E-19 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_614 4132a3835e68dc63f3a90db98879a08e 741 SUPERFAMILY SSF52540 342 634 9.31E-41 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_614 4132a3835e68dc63f3a90db98879a08e 741 Gene3D G3DSA:3.40.50.300 368 645 7.9E-96 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Gene3D G3DSA:2.40.30.10 212 313 3.3E-28 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Gene3D G3DSA:2.40.50.250 496 611 1.5E-104 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 143 2.0E-22 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Pfam PF00679 Elongation factor G C-terminus 411 495 6.8E-19 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 SUPERFAMILY SSF54980 317 401 6.71E-10 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Gene3D G3DSA:3.30.70.870 321 603 1.5E-104 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 SUPERFAMILY SSF52540 3 218 5.1E-50 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Pfam PF03144 Elongation factor Tu domain 2 232 303 3.3E-10 T 18-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 SUPERFAMILY SSF50447 161 312 3.76E-29 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 SMART SM00838 410 497 0.0046 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 SUPERFAMILY SSF54980 413 525 4.03E-22 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Gene3D G3DSA:3.30.70.240 404 495 1.5E-104 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Pfam PF00009 Elongation factor Tu GTP binding domain 4 208 1.1E-49 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 611 9.5E-238 T 18-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 18-10-2018 IPR031157 Tr-type G domain, conserved site TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 Gene3D G3DSA:3.40.50.300 2 211 4.2E-56 T 18-10-2018 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 PRINTS PR00315 GTP-binding elongation factor signature 73 83 1.1E-15 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.1E-15 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 PRINTS PR00315 GTP-binding elongation factor signature 125 134 1.1E-15 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.1E-15 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_595 d92dcd6ea51c718607481f3b34859ab5 614 PRINTS PR00315 GTP-binding elongation factor signature 89 100 1.1E-15 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_479 23e04aa87f847774111e0712090a27b7 423 Gene3D G3DSA:3.30.50.30 2 45 6.0E-15 T 18-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily TWT_479 23e04aa87f847774111e0712090a27b7 423 Pfam PF07724 AAA domain (Cdc48 subfamily) 118 311 4.3E-48 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_479 23e04aa87f847774111e0712090a27b7 423 SMART SM01086 317 412 1.2E-28 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_479 23e04aa87f847774111e0712090a27b7 423 SUPERFAMILY SSF57716 7 42 1.71E-9 T 18-10-2018 TWT_479 23e04aa87f847774111e0712090a27b7 423 Gene3D G3DSA:3.40.50.300 61 314 1.8E-98 T 18-10-2018 TWT_479 23e04aa87f847774111e0712090a27b7 423 Gene3D G3DSA:1.10.8.60 316 419 3.8E-33 T 18-10-2018 TWT_479 23e04aa87f847774111e0712090a27b7 423 SUPERFAMILY SSF52540 68 403 1.04E-62 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_479 23e04aa87f847774111e0712090a27b7 423 Pfam PF06689 ClpX C4-type zinc finger 8 44 5.9E-14 T 18-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TWT_479 23e04aa87f847774111e0712090a27b7 423 SMART SM00382 117 274 5.8E-10 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_479 23e04aa87f847774111e0712090a27b7 423 SMART SM00994 6 45 6.3E-16 T 18-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TWT_479 23e04aa87f847774111e0712090a27b7 423 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 415 47.329 T 18-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TWT_479 23e04aa87f847774111e0712090a27b7 423 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 2.6E-14 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_479 23e04aa87f847774111e0712090a27b7 423 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 404 3.6E-173 T 18-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Pfam PF00958 GMP synthase C terminal domain 419 502 1.2E-31 T 18-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Gene3D G3DSA:3.40.50.880 2 189 4.6E-46 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 SUPERFAMILY SSF54810 385 503 1.1E-41 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Gene3D G3DSA:3.40.50.620 190 385 3.1E-67 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 9.4E-8 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 4 18 9.4E-8 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 9.4E-8 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 8.1E-7 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 8.1E-7 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 8.1E-7 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 SUPERFAMILY SSF52402 186 422 6.17E-51 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Gene3D G3DSA:3.30.300.10 386 503 1.8E-46 T 18-10-2018 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Pfam PF00117 Glutamine amidotransferase class-I 6 182 1.1E-34 T 18-10-2018 IPR017926 Glutamine amidotransferase TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Pfam PF02540 NAD synthase 200 285 1.1E-5 T 18-10-2018 IPR022310 NAD/GMP synthase TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 SUPERFAMILY SSF52317 2 184 1.39E-44 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 199 503 1.4E-127 T 18-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 503 49.245 T 18-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TWT_079 c087e9ec1a4147fb8f0c672add1f6997 503 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 4 185 1.2E-58 T 18-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 PIRSF PIRSF000709 3 219 1.7E-8 T 18-10-2018 TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 Gene3D G3DSA:3.40.50.1240 1 215 1.9E-72 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 209 3.0E-89 T 18-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 220 41.64 T 18-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 199 1.6E-31 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 SUPERFAMILY SSF53254 3 212 2.21E-64 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_655 deaebe0460e4ebb4b39800a2f39c212d 221 SMART SM00855 3 180 1.3E-23 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_284 4664715fda4929881c8fee7ecee34449 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 283 2.9E-56 T 18-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_284 4664715fda4929881c8fee7ecee34449 301 SUPERFAMILY SSF52540 15 180 3.89E-32 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_284 4664715fda4929881c8fee7ecee34449 301 Gene3D G3DSA:3.40.50.300 9 184 9.3E-34 T 18-10-2018 TWT_284 4664715fda4929881c8fee7ecee34449 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 164 1.7E-17 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_284 4664715fda4929881c8fee7ecee34449 301 Hamap MF_00367 GTPase Era [era]. 10 300 29.208 T 18-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_284 4664715fda4929881c8fee7ecee34449 301 SUPERFAMILY SSF54814 195 297 2.94E-31 T 18-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TWT_284 4664715fda4929881c8fee7ecee34449 301 Pfam PF01926 50S ribosome-binding GTPase 15 111 6.3E-19 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_284 4664715fda4929881c8fee7ecee34449 301 Pfam PF07650 KH domain 213 289 1.8E-16 T 18-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_284 4664715fda4929881c8fee7ecee34449 301 Gene3D G3DSA:3.30.300.20 191 301 3.5E-33 T 18-10-2018 IPR015946 K homology domain-like, alpha/beta TWT_630 e5a882a9edb764c226b63632ee98f155 1131 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1086 1103 - T 18-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Gene3D G3DSA:3.30.470.130 1 454 1.9E-173 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 5.9E-33 T 18-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 PIRSF PIRSF001594 1 1131 0.0 T 18-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF02436 Conserved carboxylase domain 824 1008 5.9E-48 T 18-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.2E-70 T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Gene3D G3DSA:3.20.20.70 476 994 4.4E-220 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 18-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF00682 HMGL-like 530 799 7.2E-23 T 18-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF56059 84 352 2.3E-62 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Gene3D G3DSA:3.10.600.10 459 1044 4.4E-220 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF89000 829 995 2.79E-36 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SMART SM00878 339 446 2.0E-47 T 18-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF52440 2 111 6.12E-38 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Gene3D G3DSA:2.40.50.100 1054 1130 1.4E-19 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF51230 1054 1129 7.85E-17 T 18-10-2018 IPR011053 Single hybrid motif TWT_630 e5a882a9edb764c226b63632ee98f155 1131 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1129 0.0 T 18-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 111 6.8E-38 T 18-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF51246 334 448 5.23E-35 T 18-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 SUPERFAMILY SSF51569 521 832 2.38E-75 T 18-10-2018 TWT_630 e5a882a9edb764c226b63632ee98f155 1131 Pfam PF00364 Biotin-requiring enzyme 1072 1129 7.7E-15 T 18-10-2018 IPR000089 Biotin/lipoyl attachment TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 Gene3D G3DSA:3.40.50.9100 6 161 8.4E-55 T 18-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 SUPERFAMILY SSF52304 14 159 2.35E-48 T 18-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 Pfam PF01220 Dehydroquinase class II 18 156 1.1E-47 T 18-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 162 55.819 T 18-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 PIRSF PIRSF001399 15 162 2.2E-60 T 18-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 19 157 2.0E-77 T 18-10-2018 TWT_369 12ab26bab6dbd5fe9ad5f3841c3360a1 162 ProSitePatterns PS01029 Dehydroquinase class II signature. 22 39 - T 18-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TWT_325 fc5c46a7ec1306b2948613dbc2ab6284 328 SUPERFAMILY SSF51556 48 327 4.18E-67 T 18-10-2018 IPR032466 Metal-dependent hydrolase TWT_325 fc5c46a7ec1306b2948613dbc2ab6284 328 Pfam PF01026 TatD related DNase 51 325 5.9E-62 T 18-10-2018 IPR001130 TatD family GO:0016788 TWT_325 fc5c46a7ec1306b2948613dbc2ab6284 328 PIRSF PIRSF005902 4 328 3.2E-78 T 18-10-2018 IPR001130 TatD family GO:0016788 TWT_325 fc5c46a7ec1306b2948613dbc2ab6284 328 Gene3D G3DSA:3.20.20.140 44 327 1.1E-69 T 18-10-2018 TWT_749 0f24b675481e0eff1497ae74108e410a 189 SUPERFAMILY SSF58014 52 130 3.01E-9 T 18-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 Hamap MF_01151 Protein GrpE [grpE]. 5 186 14.592 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 Pfam PF01025 GrpE 35 185 1.5E-28 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 Gene3D G3DSA:2.30.22.10 131 185 3.3E-15 T 18-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 PRINTS PR00773 GrpE protein signature 138 153 2.9E-14 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 PRINTS PR00773 GrpE protein signature 165 184 2.9E-14 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 PRINTS PR00773 GrpE protein signature 91 106 2.9E-14 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 PRINTS PR00773 GrpE protein signature 63 79 2.9E-14 T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 Gene3D G3DSA:3.90.20.20 2 130 2.2E-8 T 18-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 SUPERFAMILY SSF51064 132 185 1.1E-14 T 18-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TWT_749 0f24b675481e0eff1497ae74108e410a 189 ProSitePatterns PS01071 grpE protein signature. 141 184 - T 18-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TWT_566 bba6c00541bb237ecc84b2fbee802734 768 SUPERFAMILY SSF52540 361 685 1.14E-33 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_566 bba6c00541bb237ecc84b2fbee802734 768 SUPERFAMILY SSF52540 266 517 7.23E-48 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Pfam PF00271 Helicase conserved C-terminal domain 544 658 4.8E-17 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_566 bba6c00541bb237ecc84b2fbee802734 768 SMART SM00490 569 658 6.2E-17 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Gene3D G3DSA:3.40.50.300 282 515 5.0E-66 T 18-10-2018 TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Gene3D G3DSA:3.40.50.300 523 699 2.2E-45 T 18-10-2018 TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Pfam PF17191 RecG wedge domain 92 234 3.8E-13 T 18-10-2018 IPR033454 RecG, wedge domain TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Pfam PF00270 DEAD/DEAH box helicase 365 499 2.0E-14 T 18-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TWT_566 bba6c00541bb237ecc84b2fbee802734 768 SMART SM00487 337 523 2.0E-27 T 18-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TWT_566 bba6c00541bb237ecc84b2fbee802734 768 SUPERFAMILY SSF50249 92 251 1.05E-31 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_566 bba6c00541bb237ecc84b2fbee802734 768 Gene3D G3DSA:2.40.50.140 123 220 4.6E-23 T 18-10-2018 TWT_062 41af623204b179a11f61494c0694b28d 545 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 19 535 2.0E-109 T 18-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TWT_062 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:3.40.50.620 19 287 1.3E-90 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_062 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:1.10.10.860 289 335 2.3E-23 T 18-10-2018 TWT_062 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:2.30.30.300 187 230 1.3E-90 T 18-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TWT_062 41af623204b179a11f61494c0694b28d 545 SUPERFAMILY SSF52374 19 333 1.37E-58 T 18-10-2018 TWT_062 41af623204b179a11f61494c0694b28d 545 SUPERFAMILY SSF48163 339 540 5.75E-25 T 18-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_062 41af623204b179a11f61494c0694b28d 545 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 17 543 29.09 T 18-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TWT_062 41af623204b179a11f61494c0694b28d 545 Pfam PF01921 tRNA synthetases class I (K) 18 372 3.5E-127 T 18-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TWT_062 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:1.10.10.350 438 540 2.4E-15 T 18-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TWT_062 41af623204b179a11f61494c0694b28d 545 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 54 - T 18-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SUPERFAMILY SSF54980 610 697 5.04E-30 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Gene3D G3DSA:3.30.230.10 488 694 4.0E-86 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SMART SM00889 484 605 7.2E-70 T 18-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Gene3D G3DSA:3.30.70.870 410 487 4.6E-31 T 18-10-2018 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Pfam PF03144 Elongation factor Tu domain 2 328 395 5.0E-12 T 18-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SMART SM00838 607 694 3.4E-56 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Gene3D G3DSA:3.30.70.240 611 681 4.0E-86 T 18-10-2018 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 698 0.0 T 18-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Hamap MF_00054_B Elongation factor G [fusA]. 8 698 108.528 T 18-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Pfam PF14492 Elongation Factor G, domain II 408 481 2.2E-33 T 18-10-2018 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SUPERFAMILY SSF54211 483 606 7.59E-40 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SUPERFAMILY SSF54980 406 484 4.32E-24 T 18-10-2018 IPR035647 EF-G domain III/V-like TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 1.2E-38 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Pfam PF00009 Elongation factor Tu GTP binding domain 11 288 7.2E-67 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Pfam PF03764 Elongation factor G, domain IV 483 604 7.6E-47 T 18-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Gene3D G3DSA:3.40.50.300 6 298 1.4E-113 T 18-10-2018 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SUPERFAMILY SSF50447 271 408 3.53E-32 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Gene3D G3DSA:2.40.30.10 299 409 9.2E-40 T 18-10-2018 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 18-10-2018 IPR031157 Tr-type G domain, conserved site TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 Pfam PF00679 Elongation factor G C-terminus 608 693 2.5E-30 T 18-10-2018 IPR000640 Elongation factor EFG, domain V-like TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 SUPERFAMILY SSF52540 8 288 1.96E-106 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.9E-16 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.9E-16 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.9E-16 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-16 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_675 b7d4bd2457a63f78e5b4168b5e0727e5 701 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.9E-16 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_210 45df3161be87163d952df4b8aac62f07 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 9.8E-12 T 18-10-2018 TWT_210 45df3161be87163d952df4b8aac62f07 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 9.8E-12 T 18-10-2018 TWT_210 45df3161be87163d952df4b8aac62f07 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.8E-12 T 18-10-2018 TWT_210 45df3161be87163d952df4b8aac62f07 373 Gene3D G3DSA:3.50.50.60 173 288 1.2E-21 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_210 45df3161be87163d952df4b8aac62f07 373 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.0E-11 T 18-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TWT_210 45df3161be87163d952df4b8aac62f07 373 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 331 350 1.0E-11 T 18-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TWT_210 45df3161be87163d952df4b8aac62f07 373 Gene3D G3DSA:3.50.50.60 4 99 1.5E-21 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_210 45df3161be87163d952df4b8aac62f07 373 Gene3D G3DSA:3.50.50.60 138 340 1.2E-21 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_210 45df3161be87163d952df4b8aac62f07 373 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 339 1.2E-12 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_210 45df3161be87163d952df4b8aac62f07 373 SUPERFAMILY SSF51905 7 349 1.2E-26 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_116 bb3fce535125e33e5799c241c8c085e0 93 Gene3D G3DSA:4.10.520.10 4 93 9.5E-27 T 18-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.8E-5 T 18-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.8E-5 T 18-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.8E-5 T 18-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 SUPERFAMILY SSF47729 4 93 4.71E-24 T 18-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 SMART SM00411 4 93 1.1E-23 T 18-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TWT_116 bb3fce535125e33e5799c241c8c085e0 93 Pfam PF00216 Bacterial DNA-binding protein 4 93 5.5E-25 T 18-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TWT_338 869088a5f0feb0b572fa02dc7f2f398b 351 Pfam PF02628 Cytochrome oxidase assembly protein 98 220 3.0E-8 T 18-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TWT_327 9f7de2f67f5359ff5a08819036a643ec 313 SUPERFAMILY SSF56601 6 272 2.17E-30 T 18-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TWT_327 9f7de2f67f5359ff5a08819036a643ec 313 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 78 270 3.8E-14 T 18-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TWT_327 9f7de2f67f5359ff5a08819036a643ec 313 Gene3D G3DSA:3.40.710.10 62 313 9.7E-38 T 18-10-2018 TWT_400 e011ce11a0f128f5f11b06e46fdde61c 158 SUPERFAMILY SSF54637 5 157 1.34E-24 T 18-10-2018 IPR029069 HotDog domain superfamily TWT_400 e011ce11a0f128f5f11b06e46fdde61c 158 Pfam PF03061 Thioesterase superfamily 15 121 2.0E-11 T 18-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TWT_400 e011ce11a0f128f5f11b06e46fdde61c 158 Gene3D G3DSA:3.10.129.10 3 158 2.6E-31 T 18-10-2018 TWT_785 4520f8c83c28e567b0b12908e197583b 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 410 9.3E-89 T 18-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TWT_785 4520f8c83c28e567b0b12908e197583b 426 Pfam PF13393 Histidyl-tRNA synthetase 8 340 1.4E-38 T 18-10-2018 TWT_785 4520f8c83c28e567b0b12908e197583b 426 Gene3D G3DSA:3.30.930.10 1 347 6.9E-86 T 18-10-2018 TWT_785 4520f8c83c28e567b0b12908e197583b 426 PIRSF PIRSF001549 1 410 4.8E-86 T 18-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TWT_785 4520f8c83c28e567b0b12908e197583b 426 SUPERFAMILY SSF55681 5 346 4.59E-64 T 18-10-2018 TWT_310 a836431df35b60a7989ae60871be771e 228 SUPERFAMILY SSF56420 36 214 1.15E-46 T 18-10-2018 IPR036821 Peptide deformylase superfamily TWT_310 a836431df35b60a7989ae60871be771e 228 Gene3D G3DSA:3.90.45.10 35 228 5.0E-58 T 18-10-2018 IPR036821 Peptide deformylase superfamily TWT_310 a836431df35b60a7989ae60871be771e 228 PRINTS PR01576 Peptide deformylase signature 139 150 1.0E-31 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 PRINTS PR01576 Peptide deformylase signature 170 199 1.0E-31 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 PRINTS PR01576 Peptide deformylase signature 151 169 1.0E-31 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 PRINTS PR01576 Peptide deformylase signature 65 94 1.0E-31 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 41 203 4.3E-34 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 Hamap MF_00163 Peptide deformylase [def]. 35 212 25.301 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 Pfam PF01327 Polypeptide deformylase 38 200 7.4E-40 T 18-10-2018 IPR023635 Peptide deformylase TWT_310 a836431df35b60a7989ae60871be771e 228 PIRSF PIRSF004749 8 220 1.8E-41 T 18-10-2018 IPR023635 Peptide deformylase TWT_012 83665ab639c84386845f9949ae83fc40 190 Pfam PF04011 LemA family 14 186 9.6E-65 T 18-10-2018 IPR007156 LemA TWT_012 83665ab639c84386845f9949ae83fc40 190 Gene3D G3DSA:1.20.1440.20 20 190 6.4E-61 T 18-10-2018 IPR023353 LemA-like domain superfamily TWT_012 83665ab639c84386845f9949ae83fc40 190 SUPERFAMILY SSF140478 30 177 8.37E-53 T 18-10-2018 IPR023353 LemA-like domain superfamily TWT_205 857b9feea02738c26dfa5989f0adde68 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 329 4.6E-43 T 18-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TWT_205 857b9feea02738c26dfa5989f0adde68 581 Gene3D G3DSA:3.40.50.970 367 568 6.5E-67 T 18-10-2018 TWT_205 857b9feea02738c26dfa5989f0adde68 581 SUPERFAMILY SSF52518 3 176 5.54E-56 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_205 857b9feea02738c26dfa5989f0adde68 581 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 5 566 8.6E-208 T 18-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TWT_205 857b9feea02738c26dfa5989f0adde68 581 Gene3D G3DSA:3.40.50.1220 197 366 2.9E-54 T 18-10-2018 TWT_205 857b9feea02738c26dfa5989f0adde68 581 SUPERFAMILY SSF52518 370 571 2.14E-65 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_205 857b9feea02738c26dfa5989f0adde68 581 SUPERFAMILY SSF52467 198 359 2.29E-54 T 18-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TWT_205 857b9feea02738c26dfa5989f0adde68 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 546 1.3E-47 T 18-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TWT_205 857b9feea02738c26dfa5989f0adde68 581 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 18-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TWT_205 857b9feea02738c26dfa5989f0adde68 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 170 1.8E-50 T 18-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TWT_205 857b9feea02738c26dfa5989f0adde68 581 Gene3D G3DSA:3.40.50.970 2 175 1.9E-64 T 18-10-2018 TWT_520 1c5f99d90919baa8344c708bc22adf39 993 Pfam PF13245 AAA domain 24 248 4.6E-11 T 18-10-2018 TWT_520 1c5f99d90919baa8344c708bc22adf39 993 Pfam PF12705 PD-(D/E)XK nuclease superfamily 743 960 6.2E-22 T 18-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TWT_520 1c5f99d90919baa8344c708bc22adf39 993 SMART SM00382 22 262 2.1E-4 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_520 1c5f99d90919baa8344c708bc22adf39 993 Gene3D G3DSA:3.40.50.300 310 655 2.0E-7 T 18-10-2018 TWT_520 1c5f99d90919baa8344c708bc22adf39 993 Gene3D G3DSA:1.10.486.10 376 565 2.0E-7 T 18-10-2018 TWT_520 1c5f99d90919baa8344c708bc22adf39 993 SUPERFAMILY SSF52540 20 666 1.45E-45 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_555 79a270273a02d98821bd8e94956532a8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.0E-42 T 18-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 18-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 8.0E-20 T 18-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 8.0E-20 T 18-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 8.0E-20 T 18-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.8E-31 T 18-10-2018 IPR027486 Ribosomal protein S10 domain TWT_555 79a270273a02d98821bd8e94956532a8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 25.295 T 18-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_555 79a270273a02d98821bd8e94956532a8 102 SUPERFAMILY SSF54999 5 102 5.89E-34 T 18-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TWT_555 79a270273a02d98821bd8e94956532a8 102 SMART SM01403 7 101 1.4E-47 T 18-10-2018 IPR027486 Ribosomal protein S10 domain TWT_555 79a270273a02d98821bd8e94956532a8 102 Gene3D G3DSA:3.30.70.600 1 102 1.2E-33 T 18-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TWT_153 10386981754eb6db1eca2d7b0579367f 175 Gene3D G3DSA:1.20.120.20 23 159 1.4E-5 T 18-10-2018 TWT_306 10386981754eb6db1eca2d7b0579367f 175 Gene3D G3DSA:1.20.120.20 23 159 1.4E-5 T 18-10-2018 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.30.30.30 1 61 5.6E-26 T 18-10-2018 IPR014722 Ribosomal protein L2, domain 2 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.0E-26 T 18-10-2018 IPR013185 Translation elongation factor, KOW-like TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 PIRSF PIRSF005901 1 185 4.0E-61 T 18-10-2018 IPR020599 Translation elongation factor P/YeiP TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 SMART SM00841 129 184 3.5E-29 T 18-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50249 65 126 2.91E-15 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.4E-72 T 18-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.1E-18 T 18-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.40.50.140 128 185 1.2E-23 T 18-10-2018 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50249 129 185 1.1E-15 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 18-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF09285 Elongation factor P, C-terminal 129 183 1.9E-23 T 18-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.40.50.140 64 127 1.1E-19 T 18-10-2018 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50104 2 60 2.59E-19 T 18-10-2018 IPR008991 Translation protein SH3-like domain superfamily TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 SMART SM01185 67 121 1.1E-21 T 18-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TWT_368 ade5932a1d00c7a9df30c72bf596150a 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 44.082 T 18-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 Pfam PF00117 Glutamine amidotransferase class-I 5 186 5.8E-41 T 18-10-2018 IPR017926 Glutamine amidotransferase TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 Gene3D G3DSA:3.40.50.880 2 191 1.3E-53 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 4.6E-13 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 4.6E-13 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 4.6E-13 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 50 59 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 103 111 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 123 135 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 78 89 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 166 179 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00097 Anthranilate synthase component II signature 4 18 1.5E-28 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 1.3E-8 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 1.3E-8 T 18-10-2018 TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 SUPERFAMILY SSF52317 1 188 2.07E-48 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_011 3bb83b1252b0c2f9d6ae72363c60716a 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 187 4.1E-48 T 18-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TWT_691 f53945219fcb8036e153e4152774487a 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 24 155 2.1E-37 T 18-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_691 f53945219fcb8036e153e4152774487a 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 19 156 21.316 T 18-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_691 f53945219fcb8036e153e4152774487a 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 24 154 8.1E-27 T 18-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_691 f53945219fcb8036e153e4152774487a 156 SUPERFAMILY SSF52121 16 156 1.44E-38 T 18-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_691 f53945219fcb8036e153e4152774487a 156 Gene3D G3DSA:3.40.50.960 12 156 1.4E-38 T 18-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_777 3cb090a493626a0b01a80d8476349e2b 585 SUPERFAMILY SSF56112 10 267 1.01E-75 T 18-10-2018 IPR011009 Protein kinase-like domain superfamily TWT_777 3cb090a493626a0b01a80d8476349e2b 585 SMART SM00220 13 270 6.5E-60 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_777 3cb090a493626a0b01a80d8476349e2b 585 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 18-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TWT_777 3cb090a493626a0b01a80d8476349e2b 585 Pfam PF00069 Protein kinase domain 14 257 5.3E-48 T 18-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TWT_777 3cb090a493626a0b01a80d8476349e2b 585 Gene3D G3DSA:3.30.200.20 2 92 1.1E-26 T 18-10-2018 TWT_777 3cb090a493626a0b01a80d8476349e2b 585 Gene3D G3DSA:1.10.510.10 94 276 1.6E-52 T 18-10-2018 TWT_536 cd47afbf4cd50ad2862481e248fa73da 160 SUPERFAMILY SSF52080 20 157 6.93E-33 T 18-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TWT_536 cd47afbf4cd50ad2862481e248fa73da 160 Gene3D G3DSA:3.100.10.10 81 158 2.6E-10 T 18-10-2018 TWT_536 cd47afbf4cd50ad2862481e248fa73da 160 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 18 156 1.6E-36 T 18-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_536 cd47afbf4cd50ad2862481e248fa73da 160 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 19 159 16.325 T 18-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TWT_536 cd47afbf4cd50ad2862481e248fa73da 160 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 42 157 1.8E-24 T 18-10-2018 IPR021131 Ribosomal protein L18e/L15P TWT_359 501a0c84251593dff6379f88834b1f17 624 Gene3D G3DSA:3.40.50.300 164 310 3.3E-22 T 18-10-2018 TWT_359 501a0c84251593dff6379f88834b1f17 624 Gene3D G3DSA:1.10.8.630 3 111 7.3E-12 T 18-10-2018 TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF07860 WisP family C-Terminal Region 2059 2124 2.8E-40 T 18-10-2018 IPR012421 WisP, C-terminal TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 SUPERFAMILY SSF49313 1196 1261 4.87E-6 T 18-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 SUPERFAMILY SSF49313 517 606 3.92E-7 T 18-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 641 708 9.9E-12 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1998 2042 1.6E-7 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1303 1355 1.1E-9 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1524 1575 1.5E-9 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 852 916 4.4E-15 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 537 590 9.5E-12 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1619 1669 1.7E-10 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1889 1944 1.5E-5 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1196 1247 1.1E-10 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1408 1472 7.2E-8 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1105 1144 4.1E-10 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 979 1037 1.9E-13 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 1717 1763 4.8E-7 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Pfam PF05345 Putative Ig domain 306 365 2.8E-12 T 18-10-2018 IPR008009 Putative Ig TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Gene3D G3DSA:2.60.40.10 1176 1260 8.4E-5 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Gene3D G3DSA:2.60.40.10 509 608 6.7E-8 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Gene3D G3DSA:2.60.40.10 950 1047 5.0E-9 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Gene3D G3DSA:2.60.40.10 276 375 9.3E-6 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_764 870c0219fb25b8e7fc817a6e99fd11e3 2147 Gene3D G3DSA:2.60.40.10 1495 1586 1.9E-5 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_108 52aadb7920578f1b2fddb30465c8b6b8 153 Pfam PF01250 Ribosomal protein S6 62 148 4.0E-13 T 18-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_108 52aadb7920578f1b2fddb30465c8b6b8 153 SUPERFAMILY SSF54995 59 151 9.55E-17 T 18-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_108 52aadb7920578f1b2fddb30465c8b6b8 153 Gene3D G3DSA:3.30.70.60 57 153 6.4E-15 T 18-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TWT_108 52aadb7920578f1b2fddb30465c8b6b8 153 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 59 152 13.226 T 18-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_228 190536138f53f8524839a2d4414f27b0 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 141 1.1E-37 T 18-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_228 190536138f53f8524839a2d4414f27b0 356 Gene3D G3DSA:3.40.50.2000 1 173 8.5E-51 T 18-10-2018 TWT_228 190536138f53f8524839a2d4414f27b0 356 SUPERFAMILY SSF53756 3 351 2.3E-88 T 18-10-2018 TWT_228 190536138f53f8524839a2d4414f27b0 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 337 7.8E-29 T 18-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TWT_228 190536138f53f8524839a2d4414f27b0 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 354 27.879 T 18-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_228 190536138f53f8524839a2d4414f27b0 356 Gene3D G3DSA:3.40.50.2000 174 338 6.7E-39 T 18-10-2018 TWT_294 c6dad8c43a7ae7e4d95aed02de023e68 252 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 3 204 15.768 T 18-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TWT_294 c6dad8c43a7ae7e4d95aed02de023e68 252 Pfam PF01121 Dephospho-CoA kinase 134 171 8.1E-5 T 18-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TWT_294 c6dad8c43a7ae7e4d95aed02de023e68 252 Pfam PF01121 Dephospho-CoA kinase 6 109 1.2E-13 T 18-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TWT_294 c6dad8c43a7ae7e4d95aed02de023e68 252 Gene3D G3DSA:3.40.50.300 3 250 4.7E-34 T 18-10-2018 TWT_294 c6dad8c43a7ae7e4d95aed02de023e68 252 SUPERFAMILY SSF52540 4 178 1.65E-16 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Pfam PF07568 Histidine kinase 294 366 2.3E-19 T 18-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Gene3D G3DSA:3.30.450.20 136 279 6.3E-36 T 18-10-2018 TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Gene3D G3DSA:3.30.450.280 2 129 3.0E-16 T 18-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 SMART SM00387 389 498 6.4E-5 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 SUPERFAMILY SSF55874 374 496 1.13E-15 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Gene3D G3DSA:3.30.565.10 350 501 5.4E-17 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 497 9.2E-7 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_632 1cd46ea4d71e0713bb27bcc2ee2585b1 504 Pfam PF12282 Signal transduction histidine kinase 5 113 7.1E-14 T 18-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 257 286 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 141 170 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 107 136 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 224 252 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 311 328 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 PRINTS PR00142 RecA protein signature 179 208 1.6E-83 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 ProSitePatterns PS00321 recA signature. 227 235 - T 18-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 Gene3D G3DSA:3.40.50.300 40 281 2.5E-81 T 18-10-2018 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 SUPERFAMILY SSF54752 282 339 3.01E-18 T 18-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 Pfam PF00154 recA bacterial DNA recombination protein 21 282 3.2E-139 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 18 336 6.3E-168 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 SUPERFAMILY SSF52540 21 281 1.5E-62 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 Gene3D G3DSA:3.30.250.10 282 357 5.6E-25 T 18-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 Hamap MF_00268 Protein RecA [recA]. 19 343 51.721 T 18-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TWT_611 ad1631c88f77b2677f507b2cb507b77f 447 SMART SM00382 71 242 7.6E-10 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Gene3D G3DSA:3.40.50.300 283 538 1.8E-79 T 18-10-2018 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Gene3D G3DSA:3.40.50.300 7 282 1.2E-81 T 18-10-2018 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Pfam PF00005 ABC transporter 308 458 2.9E-30 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 510 535 3.6E-4 T 18-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 271 2.3E-6 T 18-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 SUPERFAMILY SSF52540 8 259 1.49E-61 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 Pfam PF00005 ABC transporter 29 188 4.6E-27 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 SMART SM00382 37 237 3.1E-16 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 SMART SM00382 316 508 2.8E-17 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 SUPERFAMILY SSF52540 285 530 1.21E-67 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_142 ef38925d22c2ff99fbfbf306b71a6af4 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_737 c48aa656b4e78622c03a8fab5b911378 416 SMART SM00922 146 244 8.0E-9 T 18-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TWT_737 c48aa656b4e78622c03a8fab5b911378 416 SUPERFAMILY SSF51604 133 377 3.67E-34 T 18-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TWT_737 c48aa656b4e78622c03a8fab5b911378 416 Pfam PF13378 Enolase C-terminal domain-like 157 258 2.4E-12 T 18-10-2018 IPR029065 Enolase C-terminal domain-like TWT_314 f993efb34856e083401011dbe2dd7c25 83 Pfam PF01197 Ribosomal protein L31 2 79 1.8E-25 T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 45 60 4.4E-17 T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 60 78 4.4E-17 T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.4E-17 T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 SUPERFAMILY SSF143800 2 79 3.77E-20 T 18-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_314 f993efb34856e083401011dbe2dd7c25 83 Gene3D G3DSA:2.30.170.50 1 83 3.1E-23 T 18-10-2018 TWT_314 f993efb34856e083401011dbe2dd7c25 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 23.667 T 18-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_314 f993efb34856e083401011dbe2dd7c25 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 6.3E-18 T 18-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 119 126 - T 18-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 SUPERFAMILY SSF53671 72 382 1.96E-75 T 18-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 149 158 8.4E-28 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 362 376 8.4E-28 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 109 131 8.4E-28 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 203 220 8.4E-28 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 299 308 8.4E-28 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 74 216 2.0E-40 T 18-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 Gene3D G3DSA:3.40.50.1370 204 368 9.2E-89 T 18-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 228 378 2.9E-25 T 18-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 74 381 9.4E-83 T 18-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 Gene3D G3DSA:3.40.50.1370 75 377 9.2E-89 T 18-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 204 215 1.4E-15 T 18-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 119 138 1.4E-15 T 18-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 346 369 1.4E-15 T 18-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TWT_196 c24a7afae9f565939e2fe6c0b8844b5f 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 331 340 1.4E-15 T 18-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TWT_424 02334fa71557418cf298ba25b75aafc6 477 Gene3D G3DSA:2.40.10.170 8 85 1.5E-28 T 18-10-2018 TWT_424 02334fa71557418cf298ba25b75aafc6 477 Gene3D G3DSA:1.10.1140.10 357 477 5.7E-48 T 18-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_424 02334fa71557418cf298ba25b75aafc6 477 SMART SM00382 153 416 8.8E-6 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_424 02334fa71557418cf298ba25b75aafc6 477 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 2.8E-64 T 18-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_424 02334fa71557418cf298ba25b75aafc6 477 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 18-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_424 02334fa71557418cf298ba25b75aafc6 477 SUPERFAMILY SSF52540 87 359 8.26E-88 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_424 02334fa71557418cf298ba25b75aafc6 477 Gene3D G3DSA:3.40.50.300 86 356 7.3E-105 T 18-10-2018 TWT_424 02334fa71557418cf298ba25b75aafc6 477 SUPERFAMILY SSF47917 357 473 1.15E-45 T 18-10-2018 TWT_424 02334fa71557418cf298ba25b75aafc6 477 SUPERFAMILY SSF50615 9 84 3.92E-25 T 18-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_424 02334fa71557418cf298ba25b75aafc6 477 Hamap MF_01347 ATP synthase subunit beta [atpB]. 7 472 54.988 T 18-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TWT_424 02334fa71557418cf298ba25b75aafc6 477 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 9 471 5.6E-235 T 18-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TWT_424 02334fa71557418cf298ba25b75aafc6 477 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 83 5.2E-21 T 18-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_455 df552782efa9a4156d5a2e58ef98c58d 179 Hamap MF_00048 UPF0102 protein YraN [yraN]. 66 177 16.742 T 18-10-2018 IPR003509 Uncharacterised protein family UPF0102 TWT_455 df552782efa9a4156d5a2e58ef98c58d 179 SUPERFAMILY SSF52980 72 165 1.29E-20 T 18-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TWT_455 df552782efa9a4156d5a2e58ef98c58d 179 Gene3D G3DSA:3.40.1350.10 72 178 9.9E-23 T 18-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TWT_455 df552782efa9a4156d5a2e58ef98c58d 179 Pfam PF02021 Uncharacterised protein family UPF0102 73 164 8.8E-19 T 18-10-2018 IPR003509 Uncharacterised protein family UPF0102 TWT_242 eb0e2e45fea6e45a4d1fd3eb6418a702 124 SUPERFAMILY SSF89360 20 114 7.46E-29 T 18-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TWT_242 eb0e2e45fea6e45a4d1fd3eb6418a702 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 124 1.1E-35 T 18-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TWT_242 eb0e2e45fea6e45a4d1fd3eb6418a702 124 Gene3D G3DSA:2.60.300.12 19 124 6.4E-31 T 18-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TWT_242 eb0e2e45fea6e45a4d1fd3eb6418a702 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 20 121 3.6E-18 T 18-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TWT_242 eb0e2e45fea6e45a4d1fd3eb6418a702 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 18-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TWT_354 46aeee885e912e656fc77b5e7b255e6a 299 SUPERFAMILY SSF161098 50 285 2.35E-22 T 18-10-2018 IPR035906 MetI-like superfamily TWT_354 46aeee885e912e656fc77b5e7b255e6a 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 289 3.9E-14 T 18-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TWT_354 46aeee885e912e656fc77b5e7b255e6a 299 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 291 1.2E-64 T 18-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TWT_354 46aeee885e912e656fc77b5e7b255e6a 299 Gene3D G3DSA:1.10.3720.10 45 293 3.7E-25 T 18-10-2018 IPR035906 MetI-like superfamily TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 SUPERFAMILY SSF50447 705 802 2.08E-27 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 ProSitePatterns PS01176 Initiation factor 2 signature. 755 777 - T 18-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Gene3D G3DSA:2.40.30.10 473 592 8.2E-38 T 18-10-2018 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 214 265 3.3E-9 T 18-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 15 61 2.3E-7 T 18-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Pfam PF11987 Translation-initiation factor 2 588 693 1.4E-35 T 18-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 SUPERFAMILY SSF52540 301 464 1.97E-49 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Pfam PF00009 Elongation factor Tu GTP binding domain 305 461 4.1E-34 T 18-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 303 458 1.2E-29 T 18-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Gene3D G3DSA:2.40.30.10 705 803 1.1E-26 T 18-10-2018 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 SUPERFAMILY SSF52156 581 710 5.36E-35 T 18-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Gene3D G3DSA:1.10.10.2480 11 75 2.1E-10 T 18-10-2018 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Gene3D G3DSA:3.40.50.10050 596 704 2.8E-35 T 18-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 210 801 7.9E-229 T 18-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 SUPERFAMILY SSF50447 473 556 2.29E-24 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 13 802 16.509 T 18-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TWT_157 8b9fe8bd9227dd8ceeb2bdf0bdb2b667 803 Gene3D G3DSA:3.40.50.300 298 472 7.2E-69 T 18-10-2018 TWT_367 22293387f7162727c1fc076ed7f73caa 428 Gene3D G3DSA:2.30.40.10 48 425 8.1E-103 T 18-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TWT_367 22293387f7162727c1fc076ed7f73caa 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 48 427 3.3E-95 T 18-10-2018 TWT_367 22293387f7162727c1fc076ed7f73caa 428 Gene3D G3DSA:3.20.20.140 66 372 8.1E-103 T 18-10-2018 TWT_367 22293387f7162727c1fc076ed7f73caa 428 SUPERFAMILY SSF51556 65 371 1.23E-85 T 18-10-2018 IPR032466 Metal-dependent hydrolase TWT_367 22293387f7162727c1fc076ed7f73caa 428 Pfam PF01979 Amidohydrolase family 61 425 1.9E-18 T 18-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TWT_367 22293387f7162727c1fc076ed7f73caa 428 SUPERFAMILY SSF51338 47 428 1.41E-13 T 18-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 Gene3D G3DSA:1.10.8.420 1 52 1.8E-17 T 18-10-2018 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 Gene3D G3DSA:3.40.1360.10 76 197 8.2E-47 T 18-10-2018 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 18-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 SMART SM00493 79 164 1.4E-16 T 18-10-2018 IPR006171 TOPRIM domain TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 1.8E-80 T 18-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 SUPERFAMILY SSF111304 2 197 7.72E-74 T 18-10-2018 IPR023627 Recombination protein RecR TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 Pfam PF02132 RecR protein 39 77 2.9E-16 T 18-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 102.075 T 18-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TWT_709 6127a77f6a084d99dcb2e7f0f70d8952 198 Pfam PF13662 Toprim domain 80 170 8.6E-25 T 18-10-2018 IPR006171 TOPRIM domain TWT_532 79700fa65da9a52e877ea8e3dada5b00 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 8.7E-36 T 18-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TWT_532 79700fa65da9a52e877ea8e3dada5b00 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.3E-27 T 18-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TWT_532 79700fa65da9a52e877ea8e3dada5b00 73 Gene3D G3DSA:2.40.50.140 1 73 1.3E-36 T 18-10-2018 TWT_532 79700fa65da9a52e877ea8e3dada5b00 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.032 T 18-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TWT_532 79700fa65da9a52e877ea8e3dada5b00 73 SUPERFAMILY SSF50249 4 72 1.54E-25 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 8 284 1.6E-126 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 6 286 49.622 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 317 1024 17.381 T 18-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Gene3D G3DSA:3.30.930.10 1 209 9.4E-100 T 18-10-2018 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 246 262 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 60 75 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 161 176 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 138 158 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 81 101 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 112 136 1.2E-53 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 318 1017 2.1E-121 T 18-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 321 879 2.5E-137 T 18-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 SUPERFAMILY SSF109604 673 815 2.01E-9 T 18-10-2018 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 8 286 9.8E-116 T 18-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 SUPERFAMILY SSF55681 7 285 8.7E-111 T 18-10-2018 TWT_500 011a0e63d3969c30ec749fb371bd834b 1024 Gene3D G3DSA:1.20.58.180 210 289 3.6E-26 T 18-10-2018 TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 Pfam PF08328 Adenylosuccinate lyase C-terminal 328 448 3.1E-44 T 18-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 3.8E-14 T 18-10-2018 IPR000362 Fumarate lyase family TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 160 178 3.8E-14 T 18-10-2018 IPR000362 Fumarate lyase family TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 291 307 3.8E-14 T 18-10-2018 IPR000362 Fumarate lyase family TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 114 132 3.8E-14 T 18-10-2018 IPR000362 Fumarate lyase family TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 Pfam PF00206 Lyase 14 308 8.1E-46 T 18-10-2018 IPR022761 Fumarate lyase, N-terminal TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.10.40.30 379 448 9.2E-138 T 18-10-2018 TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 SUPERFAMILY SSF48557 10 456 6.6E-90 T 18-10-2018 IPR008948 L-Aspartase-like GO:0003824 TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.10.275.10 1 114 7.7E-29 T 18-10-2018 IPR024083 Fumarase/histidase, N-terminal TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 ProSitePatterns PS00163 Fumarate lyases signature. 291 300 - T 18-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TWT_791 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.20.200.10 115 449 9.2E-138 T 18-10-2018 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 18-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 Gene3D G3DSA:3.30.70.20 2 106 3.9E-44 T 18-10-2018 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.5E-16 T 18-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.5E-16 T 18-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.5E-16 T 18-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 SUPERFAMILY SSF54862 3 95 4.85E-21 T 18-10-2018 TWT_575 0cf81ec86f668a8fe48ce1238652addd 108 Pfam PF00037 4Fe-4S binding domain 34 56 5.5E-9 T 18-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 4 468 4.7E-151 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 268 292 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 186 200 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 61 77 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 216 242 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 293 311 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 243 267 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 PRINTS PR01050 Pyruvate kinase family signature 312 328 7.1E-64 T 18-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 SUPERFAMILY SSF51621 2 337 1.51E-91 T 18-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 SUPERFAMILY SSF50800 72 166 8.02E-24 T 18-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 Gene3D G3DSA:2.40.33.10 72 168 1.1E-158 T 18-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 SUPERFAMILY SSF52935 322 469 3.53E-33 T 18-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 4.4E-26 T 18-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 Gene3D G3DSA:3.40.1380.20 335 465 1.1E-158 T 18-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 18-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 Pfam PF00224 Pyruvate kinase, barrel domain 3 337 1.2E-113 T 18-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TWT_290 d958f8f1ad01f4cbe81f72315be65304 473 Gene3D G3DSA:3.20.20.60 4 334 1.1E-158 T 18-10-2018 TWT_474 3fe57e5392a498c7e3978ea5cfc68723 549 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 78 465 4.6E-126 T 18-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TWT_474 3fe57e5392a498c7e3978ea5cfc68723 549 SUPERFAMILY SSF50249 103 182 5.94E-14 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_474 3fe57e5392a498c7e3978ea5cfc68723 549 Pfam PF10150 Ribonuclease E/G family 178 443 2.4E-93 T 18-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TWT_474 3fe57e5392a498c7e3978ea5cfc68723 549 Gene3D G3DSA:2.40.50.140 95 182 5.8E-25 T 18-10-2018 TWT_713 87f873a3d5ddc68381633030135b7c78 227 SUPERFAMILY SSF56808 6 224 8.11E-71 T 18-10-2018 IPR023674 Ribosomal protein L1-like TWT_713 87f873a3d5ddc68381633030135b7c78 227 Gene3D G3DSA:3.30.190.20 25 222 1.8E-72 T 18-10-2018 TWT_713 87f873a3d5ddc68381633030135b7c78 227 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 18-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_713 87f873a3d5ddc68381633030135b7c78 227 Gene3D G3DSA:3.40.50.790 68 159 1.8E-72 T 18-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TWT_713 87f873a3d5ddc68381633030135b7c78 227 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 226 37.872 T 18-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TWT_713 87f873a3d5ddc68381633030135b7c78 227 PIRSF PIRSF002155 1 227 1.2E-67 T 18-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_713 87f873a3d5ddc68381633030135b7c78 227 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.9E-44 T 18-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TWT_713 87f873a3d5ddc68381633030135b7c78 227 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 1.3E-89 T 18-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TWT_087 f6c7ee69cd3e98f8d9804bbd268a26eb 377 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 16 359 16.166 T 18-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_087 f6c7ee69cd3e98f8d9804bbd268a26eb 377 Gene3D G3DSA:3.30.2350.10 11 254 5.1E-77 T 18-10-2018 TWT_087 f6c7ee69cd3e98f8d9804bbd268a26eb 377 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 18 222 1.9E-64 T 18-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_087 f6c7ee69cd3e98f8d9804bbd268a26eb 377 SUPERFAMILY SSF55120 16 224 6.19E-67 T 18-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_087 f6c7ee69cd3e98f8d9804bbd268a26eb 377 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 38 189 9.6E-49 T 18-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TWT_438 807face8d51baae2348c0cd5a62deacf 350 PIRSF PIRSF038945 1 340 5.4E-142 T 18-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TWT_438 807face8d51baae2348c0cd5a62deacf 350 Gene3D G3DSA:3.40.50.1100 10 319 1.4E-110 T 18-10-2018 TWT_438 807face8d51baae2348c0cd5a62deacf 350 TIGRFAM TIGR00260 thrC: threonine synthase 10 319 2.8E-80 T 18-10-2018 IPR004450 Threonine synthase-like TWT_438 807face8d51baae2348c0cd5a62deacf 350 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 313 1.8E-68 T 18-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TWT_438 807face8d51baae2348c0cd5a62deacf 350 SUPERFAMILY SSF53686 2 332 1.31E-95 T 18-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TWT_438 807face8d51baae2348c0cd5a62deacf 350 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 18-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TWT_438 807face8d51baae2348c0cd5a62deacf 350 Gene3D G3DSA:3.40.50.1100 59 155 1.4E-110 T 18-10-2018 TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 SUPERFAMILY SSF47781 124 193 1.05E-27 T 18-10-2018 IPR010994 RuvA domain 2-like TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 127 193 1.8E-19 T 18-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 Pfam PF10531 SLBB domain 70 123 7.9E-11 T 18-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 Gene3D G3DSA:1.10.150.280 123 193 2.5E-23 T 18-10-2018 TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 SMART SM00278 171 190 1.6 T 18-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 SMART SM00278 141 160 0.062 T 18-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TWT_384 dc74c4405f15f13a98402ac78bcc9d71 193 Pfam PF12836 Helix-hairpin-helix motif 130 191 3.8E-22 T 18-10-2018 TWT_546 009cce557f139b2b2e757c5843e5a1bf 87 Pfam PF00831 Ribosomal L29 protein 19 74 5.1E-23 T 18-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_546 009cce557f139b2b2e757c5843e5a1bf 87 SUPERFAMILY SSF46561 17 77 2.09E-19 T 18-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_546 009cce557f139b2b2e757c5843e5a1bf 87 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 15 74 16.545 T 18-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_546 009cce557f139b2b2e757c5843e5a1bf 87 TIGRFAM TIGR00012 L29: ribosomal protein uL29 19 74 4.2E-19 T 18-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_546 009cce557f139b2b2e757c5843e5a1bf 87 Gene3D G3DSA:1.10.287.310 15 77 3.6E-24 T 18-10-2018 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 SUPERFAMILY SSF51366 3 278 3.85E-44 T 18-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 91 104 - T 18-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 Gene3D G3DSA:3.20.20.70 3 295 2.5E-65 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 164 1.9E-20 T 18-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 SMART SM00934 17 284 4.0E-7 T 18-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_364 3b3e24f0ddcc545775d5eb3da6563e98 303 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 286 8.8E-97 T 18-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_236 a61d6ff5294d6682cc8832d13ae5400e 158 Gene3D G3DSA:1.10.1660.10 13 85 5.8E-13 T 18-10-2018 TWT_236 a61d6ff5294d6682cc8832d13ae5400e 158 Pfam PF13411 MerR HTH family regulatory protein 19 84 1.7E-14 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_236 a61d6ff5294d6682cc8832d13ae5400e 158 SUPERFAMILY SSF46955 19 100 2.2E-14 T 18-10-2018 IPR009061 Putative DNA-binding domain superfamily TWT_236 a61d6ff5294d6682cc8832d13ae5400e 158 SMART SM00422 14 86 6.8E-15 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_088 dbfe71298df0c84e7eefddaeaf732be7 375 Gene3D G3DSA:2.30.42.10 137 216 1.0E-12 T 18-10-2018 TWT_088 dbfe71298df0c84e7eefddaeaf732be7 375 Pfam PF02163 Peptidase family M50 10 329 5.7E-47 T 18-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TWT_088 dbfe71298df0c84e7eefddaeaf732be7 375 Pfam PF13180 PDZ domain 141 196 3.3E-7 T 18-10-2018 IPR001478 PDZ domain GO:0005515 TWT_088 dbfe71298df0c84e7eefddaeaf732be7 375 SUPERFAMILY SSF50156 99 202 1.71E-15 T 18-10-2018 IPR036034 PDZ superfamily GO:0005515 TWT_088 dbfe71298df0c84e7eefddaeaf732be7 375 SMART SM00228 131 194 2.0E-6 T 18-10-2018 IPR001478 PDZ domain GO:0005515 TWT_058 5eeac1cf09de1b6005d454300dbb1ed2 277 Pfam PF00005 ABC transporter 33 180 3.1E-30 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_058 5eeac1cf09de1b6005d454300dbb1ed2 277 SMART SM00382 42 229 3.7E-15 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_058 5eeac1cf09de1b6005d454300dbb1ed2 277 Gene3D G3DSA:3.40.50.300 17 269 2.1E-67 T 18-10-2018 TWT_058 5eeac1cf09de1b6005d454300dbb1ed2 277 SUPERFAMILY SSF52540 16 242 2.06E-59 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_058 5eeac1cf09de1b6005d454300dbb1ed2 277 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_450 e84c5305b133a9048c3f4f1506388cbb 264 SUPERFAMILY SSF51261 68 174 1.1E-15 T 18-10-2018 IPR011055 Duplicated hybrid motif TWT_450 e84c5305b133a9048c3f4f1506388cbb 264 Pfam PF01551 Peptidase family M23 101 171 6.2E-14 T 18-10-2018 IPR016047 Peptidase M23 TWT_103 d4029fe7d2d5166a692af44d713dcd20 301 Gene3D G3DSA:2.60.200.30 139 275 2.8E-70 T 18-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TWT_103 d4029fe7d2d5166a692af44d713dcd20 301 Hamap MF_00361 NAD kinase [nadK]. 27 298 26.909 T 18-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TWT_103 d4029fe7d2d5166a692af44d713dcd20 301 Gene3D G3DSA:3.40.50.10330 77 292 2.8E-70 T 18-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TWT_103 d4029fe7d2d5166a692af44d713dcd20 301 SUPERFAMILY SSF111331 78 299 2.88E-68 T 18-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TWT_103 d4029fe7d2d5166a692af44d713dcd20 301 Pfam PF01513 ATP-NAD kinase 12 277 1.3E-49 T 18-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TWT_553 ba76d09397b8d83955ee804b88c8a8e2 248 SUPERFAMILY SSF52166 5 203 1.96E-65 T 18-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TWT_553 ba76d09397b8d83955ee804b88c8a8e2 248 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 20 201 7.8E-62 T 18-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_553 ba76d09397b8d83955ee804b88c8a8e2 248 Pfam PF00573 Ribosomal protein L4/L1 family 20 200 3.7E-57 T 18-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TWT_553 ba76d09397b8d83955ee804b88c8a8e2 248 Gene3D G3DSA:3.40.1370.10 3 205 3.0E-61 T 18-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TWT_553 ba76d09397b8d83955ee804b88c8a8e2 248 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 207 30.36 T 18-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 95 6.6E-25 T 18-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 409 2.0E-121 T 18-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Gene3D G3DSA:3.30.470.20 177 315 2.6E-47 T 18-10-2018 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 34.307 T 18-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 96 281 4.3E-55 T 18-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 275 282 - T 18-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Gene3D G3DSA:3.30.1490.20 116 176 5.0E-8 T 18-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Gene3D G3DSA:3.90.600.10 316 410 5.6E-22 T 18-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 SMART SM01209 96 281 6.4E-85 T 18-10-2018 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 SMART SM01210 316 411 4.9E-30 T 18-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Gene3D G3DSA:3.40.50.20 1 88 2.1E-25 T 18-10-2018 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 SUPERFAMILY SSF56059 97 306 1.61E-48 T 18-10-2018 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 SUPERFAMILY SSF52440 1 96 6.76E-23 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_725 a59e0bb0f0afc279971a0456829e268f 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 317 408 1.5E-21 T 18-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_725 a59e0bb0f0afc279971a0456829e268f 419 SUPERFAMILY SSF51246 314 409 4.32E-20 T 18-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 SUPERFAMILY SSF54368 13 111 7.85E-29 T 18-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 SUPERFAMILY SSF55931 112 481 7.46E-131 T 18-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 269 284 - T 18-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 Gene3D G3DSA:3.10.20.70 12 114 7.5E-31 T 18-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 SMART SM01230 112 391 2.7E-144 T 18-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 Pfam PF00120 Glutamine synthetase, catalytic domain 113 479 1.6E-125 T 18-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 25 105 5.2E-24 T 18-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 15 480 8.1E-184 T 18-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TWT_261 bbe4de3dec2c42074cba06c0d686d720 482 Gene3D G3DSA:3.30.590.10 115 470 3.3E-139 T 18-10-2018 TWT_543 5721aee4759bb7c1d3865b1f8610249a 113 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 106 19.32 T 18-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_543 5721aee4759bb7c1d3865b1f8610249a 113 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 111 2.8E-26 T 18-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_543 5721aee4759bb7c1d3865b1f8610249a 113 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 111 5.1E-19 T 18-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_543 5721aee4759bb7c1d3865b1f8610249a 113 Gene3D G3DSA:2.30.30.30 1 111 9.2E-28 T 18-10-2018 IPR014722 Ribosomal protein L2, domain 2 TWT_543 5721aee4759bb7c1d3865b1f8610249a 113 SUPERFAMILY SSF50104 3 109 4.81E-22 T 18-10-2018 IPR008991 Translation protein SH3-like domain superfamily TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 259 7.6E-80 T 18-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 PIRSF PIRSF006487 1 356 6.4E-76 T 18-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Gene3D G3DSA:4.10.1250.10 239 278 2.7E-6 T 18-10-2018 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Gene3D G3DSA:3.30.70.1400 54 139 3.7E-70 T 18-10-2018 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Gene3D G3DSA:3.30.1360.120 7 237 3.7E-70 T 18-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 SUPERFAMILY SSF103025 4 262 8.32E-74 T 18-10-2018 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 SUPERFAMILY SSF101790 275 355 2.45E-24 T 18-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 279 351 1.4E-16 T 18-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 356 5.0E-86 T 18-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TWT_638 cc40e686cbe7f81bf6358692c8e51d8d 356 Gene3D G3DSA:2.40.30.110 279 356 1.1E-24 T 18-10-2018 TWT_710 9183f562a700c089815cebd369e45bac 522 SMART SM00382 39 185 5.7E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_710 9183f562a700c089815cebd369e45bac 522 Gene3D G3DSA:1.10.8.60 10 231 1.4E-89 T 18-10-2018 TWT_710 9183f562a700c089815cebd369e45bac 522 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 6 359 2.8E-111 T 18-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TWT_710 9183f562a700c089815cebd369e45bac 522 SUPERFAMILY SSF48019 250 363 2.04E-12 T 18-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TWT_710 9183f562a700c089815cebd369e45bac 522 Pfam PF13177 DNA polymerase III, delta subunit 23 180 4.2E-36 T 18-10-2018 TWT_710 9183f562a700c089815cebd369e45bac 522 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 250 359 1.2E-9 T 18-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TWT_710 9183f562a700c089815cebd369e45bac 522 Gene3D G3DSA:3.40.50.300 15 181 1.4E-89 T 18-10-2018 TWT_710 9183f562a700c089815cebd369e45bac 522 SUPERFAMILY SSF52540 36 227 9.86E-51 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 SUPERFAMILY SSF50104 127 271 9.03E-56 T 18-10-2018 IPR008991 Translation protein SH3-like domain superfamily TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 SUPERFAMILY SSF50249 2 125 9.6E-48 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 18-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.431 T 18-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:2.40.50.140 1 115 4.7E-45 T 18-10-2018 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 3.1E-123 T 18-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:4.10.950.10 197 274 7.5E-32 T 18-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 PIRSF PIRSF002158 13 275 1.0E-97 T 18-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 SMART SM01383 42 119 3.4E-42 T 18-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 SMART SM01382 125 253 1.2E-85 T 18-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:2.30.30.30 116 196 6.6E-29 T 18-10-2018 IPR014722 Ribosomal protein L2, domain 2 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 1.2E-53 T 18-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TWT_551 5c926327d0e0e9cb1f902fc1bf3600f6 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 1.4E-33 T 18-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Gene3D G3DSA:3.40.50.800 6 569 6.5E-172 T 18-10-2018 IPR036621 Anticodon-binding domain superfamily TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 483 1.9E-39 T 18-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Pfam PF03129 Anticodon binding domain 508 581 1.9E-10 T 18-10-2018 IPR004154 Anticodon-binding TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Pfam PF04073 Aminoacyl-tRNA editing domain 282 405 4.1E-6 T 18-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 SUPERFAMILY SSF52954 488 582 2.62E-19 T 18-10-2018 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Gene3D G3DSA:3.30.930.10 13 489 6.5E-172 T 18-10-2018 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.1E-15 T 18-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.1E-15 T 18-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 2.1E-15 T 18-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 2.1E-15 T 18-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Gene3D G3DSA:3.90.960.10 241 415 6.5E-172 T 18-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 586 33.097 T 18-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 SUPERFAMILY SSF55681 12 502 1.49E-85 T 18-10-2018 TWT_183 8a9d858773e9ad38deac6549b9b11934 613 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 5 576 1.8E-137 T 18-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TWT_420 0e0ed1351bbeaec5b73184c01dc84230 312 Pfam PF01545 Cation efflux family 26 219 2.0E-36 T 18-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TWT_420 0e0ed1351bbeaec5b73184c01dc84230 312 SUPERFAMILY SSF160240 221 297 4.71E-8 T 18-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TWT_420 0e0ed1351bbeaec5b73184c01dc84230 312 SUPERFAMILY SSF161111 23 220 2.62E-41 T 18-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TWT_420 0e0ed1351bbeaec5b73184c01dc84230 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 296 2.6E-62 T 18-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TWT_420 0e0ed1351bbeaec5b73184c01dc84230 312 Gene3D G3DSA:1.20.1510.10 22 219 3.6E-31 T 18-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 351 34.011 T 18-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 2 349 2.2E-83 T 18-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 Gene3D G3DSA:2.30.30.280 210 274 6.5E-14 T 18-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 Gene3D G3DSA:2.40.30.10 283 357 6.7E-10 T 18-10-2018 TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 Pfam PF03054 tRNA methyl transferase 2 349 1.0E-108 T 18-10-2018 TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 Gene3D G3DSA:3.40.50.620 1 208 7.2E-70 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_415 d19cc1fcf4fe57c8689e07d8b31bb4a3 359 SUPERFAMILY SSF52402 2 240 1.15E-42 T 18-10-2018 TWT_423 7a1636134eb66513a5938a227fe2cc37 94 SUPERFAMILY SSF51344 3 84 7.59E-16 T 18-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_423 7a1636134eb66513a5938a227fe2cc37 94 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 82 4.5E-15 T 18-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_423 7a1636134eb66513a5938a227fe2cc37 94 Gene3D G3DSA:2.60.15.10 3 87 8.6E-15 T 18-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_423 7a1636134eb66513a5938a227fe2cc37 94 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 80 3.0E-8 T 18-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_665 4bc97ca1fac1eb40ab097678f0a1b578 482 Pfam PF05345 Putative Ig domain 365 413 3.1E-9 T 18-10-2018 IPR008009 Putative Ig TWT_760 4bc97ca1fac1eb40ab097678f0a1b578 482 Pfam PF05345 Putative Ig domain 365 413 3.1E-9 T 18-10-2018 IPR008009 Putative Ig TWT_083 25b6b73626c79d294ad111778571ad4c 215 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 9 193 25.711 T 18-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TWT_083 25b6b73626c79d294ad111778571ad4c 215 Gene3D G3DSA:3.40.50.170 2 206 1.3E-62 T 18-10-2018 TWT_083 25b6b73626c79d294ad111778571ad4c 215 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 194 3.2E-53 T 18-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TWT_083 25b6b73626c79d294ad111778571ad4c 215 SUPERFAMILY SSF53328 8 197 2.62E-53 T 18-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_083 25b6b73626c79d294ad111778571ad4c 215 Pfam PF00551 Formyl transferase 8 187 5.1E-44 T 18-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_113 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Gene3D G3DSA:2.30.170.40 2 78 1.9E-25 T 18-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_113 45c5d04a8d2347ac52fe7dca7bf0ce91 78 SUPERFAMILY SSF143800 2 77 7.26E-25 T 18-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_113 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Pfam PF00830 Ribosomal L28 family 4 61 2.8E-22 T 18-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_113 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 17.868 T 18-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_113 45c5d04a8d2347ac52fe7dca7bf0ce91 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 4.9E-20 T 18-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_435 77d395e761278152f4804dbd8afe6998 347 Pfam PF00472 RF-1 domain 210 317 4.0E-39 T 18-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TWT_435 77d395e761278152f4804dbd8afe6998 347 SUPERFAMILY SSF75620 25 343 9.81E-112 T 18-10-2018 TWT_435 77d395e761278152f4804dbd8afe6998 347 Pfam PF03462 PCRF domain 13 199 1.5E-52 T 18-10-2018 IPR005139 Peptide chain release factor GO:0006415 TWT_435 77d395e761278152f4804dbd8afe6998 347 Gene3D G3DSA:3.30.70.1660 102 338 3.9E-88 T 18-10-2018 TWT_435 77d395e761278152f4804dbd8afe6998 347 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 224 240 - T 18-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TWT_435 77d395e761278152f4804dbd8afe6998 347 Gene3D G3DSA:3.30.160.20 206 293 3.9E-88 T 18-10-2018 TWT_435 77d395e761278152f4804dbd8afe6998 347 SMART SM00937 61 174 2.5E-37 T 18-10-2018 IPR005139 Peptide chain release factor GO:0006415 TWT_729 193ce57a5a90e8e391312864257a0875 466 Gene3D G3DSA:3.90.1150.10 8 442 6.4E-143 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_729 193ce57a5a90e8e391312864257a0875 466 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 451 93.761 T 18-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TWT_729 193ce57a5a90e8e391312864257a0875 466 Gene3D G3DSA:3.40.640.10 69 344 6.4E-143 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_729 193ce57a5a90e8e391312864257a0875 466 Pfam PF00202 Aminotransferase class-III 283 443 1.1E-18 T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_729 193ce57a5a90e8e391312864257a0875 466 Pfam PF00202 Aminotransferase class-III 32 259 7.2E-44 T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_729 193ce57a5a90e8e391312864257a0875 466 SUPERFAMILY SSF53383 2 448 2.66E-106 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 21 249 37.818 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 194 211 - T 18-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 SUPERFAMILY SSF64005 19 243 2.22E-80 T 18-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 Pfam PF01255 Putative undecaprenyl diphosphate synthase 28 248 1.6E-72 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 21 248 3.8E-75 T 18-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TWT_286 1eae14f255e0d8dd50820ea52e28c99b 249 Gene3D G3DSA:3.40.1180.10 5 243 3.4E-91 T 18-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 334 9.0E-55 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 SUPERFAMILY SSF55424 353 463 1.27E-24 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 Gene3D G3DSA:3.50.50.60 17 337 1.6E-88 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 456 1.2E-21 T 18-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 Gene3D G3DSA:3.30.390.30 347 465 8.7E-30 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 1.2E-31 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 1.2E-31 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.2E-31 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.2E-31 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 286 1.2E-31 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PIRSF PIRSF000350 3 465 2.6E-67 T 18-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 SUPERFAMILY SSF51905 10 343 3.05E-46 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 48 63 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 16 38 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 285 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 428 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 455 8.7E-50 T 18-10-2018 TWT_019 6b0aa438c4acaf159be4415ac2269e5c 473 Gene3D G3DSA:3.50.50.60 161 279 1.6E-88 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 Gene3D G3DSA:3.10.105.10 279 498 2.1E-94 T 18-10-2018 TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 Gene3D G3DSA:3.90.76.10 63 180 2.1E-94 T 18-10-2018 TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 PIRSF PIRSF002741 27 521 2.9E-63 T 18-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 448 3.5E-58 T 18-10-2018 IPR000914 Solute-binding protein family 5 domain TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 SUPERFAMILY SSF53850 30 524 1.52E-92 T 18-10-2018 TWT_136 b84a5ad6cab3aa683b06a2ead4d7d857 526 Gene3D G3DSA:3.40.190.10 44 509 2.1E-94 T 18-10-2018 TWT_098 17243aa6cd1d9bda8cdef84cce319a1c 202 Gene3D G3DSA:3.90.79.10 2 198 3.2E-46 T 18-10-2018 TWT_098 17243aa6cd1d9bda8cdef84cce319a1c 202 SUPERFAMILY SSF55811 3 174 2.44E-36 T 18-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TWT_098 17243aa6cd1d9bda8cdef84cce319a1c 202 Pfam PF00293 NUDIX domain 39 154 1.1E-16 T 18-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 Gene3D G3DSA:3.40.50.620 7 183 6.5E-52 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_581 e61d06e5348e579672f82ad38b4f2953 312 PIRSF PIRSF004491 1 312 1.7E-104 T 18-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 SUPERFAMILY SSF82114 173 308 8.94E-35 T 18-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 SUPERFAMILY SSF52374 14 173 5.07E-30 T 18-10-2018 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 Pfam PF01687 Riboflavin kinase 182 307 2.3E-30 T 18-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 83 2.2E-8 T 18-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 Pfam PF06574 FAD synthetase 13 164 1.5E-42 T 18-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 SMART SM00904 181 308 2.1E-48 T 18-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 308 2.6E-65 T 18-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TWT_581 e61d06e5348e579672f82ad38b4f2953 312 Gene3D G3DSA:2.40.30.30 184 311 1.3E-35 T 18-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 119 135 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 300 319 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 29 47 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 95 114 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 136 153 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 339 357 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 165 185 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 222 243 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 PRINTS PR00681 Ribosomal protein S1 signature 47 61 2.0E-76 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Gene3D G3DSA:2.40.50.140 277 360 1.4E-25 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SMART SM00316 200 270 2.2E-27 T 18-10-2018 IPR022967 RNA-binding domain, S1 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SMART SM00316 285 356 5.5E-23 T 18-10-2018 IPR022967 RNA-binding domain, S1 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SMART SM00316 114 181 6.3E-10 T 18-10-2018 IPR022967 RNA-binding domain, S1 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SMART SM00316 27 98 8.4E-13 T 18-10-2018 IPR022967 RNA-binding domain, S1 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SUPERFAMILY SSF50249 270 358 5.97E-24 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SUPERFAMILY SSF50249 101 185 2.39E-14 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Pfam PF00575 S1 RNA binding domain 284 356 1.5E-16 T 18-10-2018 IPR003029 S1 domain GO:0003676 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Pfam PF00575 S1 RNA binding domain 118 181 1.7E-12 T 18-10-2018 IPR003029 S1 domain GO:0003676 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Pfam PF00575 S1 RNA binding domain 28 98 1.5E-11 T 18-10-2018 IPR003029 S1 domain GO:0003676 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Pfam PF00575 S1 RNA binding domain 200 270 3.0E-25 T 18-10-2018 IPR003029 S1 domain GO:0003676 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SUPERFAMILY SSF50249 200 282 1.79E-26 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_293 50ddb02d5f7d27cce972fac978aef013 473 SUPERFAMILY SSF50249 9 123 6.71E-22 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Gene3D G3DSA:2.40.50.140 110 188 1.0E-10 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Gene3D G3DSA:2.40.50.140 197 276 2.7E-30 T 18-10-2018 TWT_293 50ddb02d5f7d27cce972fac978aef013 473 Gene3D G3DSA:2.40.50.140 17 109 2.7E-21 T 18-10-2018 TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Pfam PF00288 GHMP kinases N terminal domain 251 309 4.7E-8 T 18-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Gene3D G3DSA:3.30.70.890 325 462 2.9E-25 T 18-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 7 457 24.086 T 18-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 SUPERFAMILY SSF54211 5 333 1.48E-25 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 SUPERFAMILY SSF55060 328 452 1.21E-19 T 18-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Pfam PF08544 GHMP kinases C terminal 378 447 5.1E-7 T 18-10-2018 IPR013750 GHMP kinase, C-terminal domain TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Gene3D G3DSA:3.30.230.10 1 87 2.8E-8 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_605 7f8c52f398ed8e2d1bce9563ecab7df2 467 Gene3D G3DSA:3.30.230.10 188 322 4.4E-27 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_316 47efb37943307e9be39518f12f443627 450 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 322 2.9E-61 T 18-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TWT_316 47efb37943307e9be39518f12f443627 450 SUPERFAMILY SSF52374 24 320 5.35E-49 T 18-10-2018 TWT_316 47efb37943307e9be39518f12f443627 450 Gene3D G3DSA:3.40.50.620 2 314 1.5E-69 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_316 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 186 204 9.4E-18 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_316 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 219 240 9.4E-18 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_316 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 9.4E-18 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_316 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 9.4E-18 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_189 547504507df8c13e990234cf579b031b 444 Pfam PF00437 Type II/IV secretion system protein 106 376 1.3E-54 T 18-10-2018 IPR001482 Type II/IV secretion system protein TWT_189 547504507df8c13e990234cf579b031b 444 Gene3D G3DSA:3.40.50.300 204 436 3.8E-52 T 18-10-2018 TWT_189 547504507df8c13e990234cf579b031b 444 SUPERFAMILY SSF52540 88 405 5.06E-42 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_189 547504507df8c13e990234cf579b031b 444 Gene3D G3DSA:3.30.450.380 28 199 1.8E-31 T 18-10-2018 TWT_123 a9162bc06de4b4a9cc02484e81d06eef 115 Pfam PF02467 Transcription factor WhiB 42 104 1.9E-26 T 18-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TWT_123 a9162bc06de4b4a9cc02484e81d06eef 115 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 36 110 18.973 T 18-10-2018 IPR003482 Transcription factor WhiB TWT_712 89d41229e56d67cc504f7177dcabc8ba 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 155 18.154 T 18-10-2018 IPR022973 Ribosomal protein L10 TWT_712 89d41229e56d67cc504f7177dcabc8ba 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 3 37 - T 18-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_712 89d41229e56d67cc504f7177dcabc8ba 166 SUPERFAMILY SSF160369 3 160 2.88E-37 T 18-10-2018 TWT_712 89d41229e56d67cc504f7177dcabc8ba 166 Gene3D G3DSA:3.30.70.1730 2 145 3.0E-33 T 18-10-2018 TWT_712 89d41229e56d67cc504f7177dcabc8ba 166 Pfam PF00466 Ribosomal protein L10 3 94 3.4E-21 T 18-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TWT_584 b283def47e5ab2371dc76b8a17ec20dc 275 Gene3D G3DSA:3.40.50.300 21 262 1.8E-46 T 18-10-2018 TWT_584 b283def47e5ab2371dc76b8a17ec20dc 275 SUPERFAMILY SSF52540 31 256 1.1E-45 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_584 b283def47e5ab2371dc76b8a17ec20dc 275 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_584 b283def47e5ab2371dc76b8a17ec20dc 275 Pfam PF00005 ABC transporter 58 195 8.9E-22 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_584 b283def47e5ab2371dc76b8a17ec20dc 275 SMART SM00382 66 243 2.0E-6 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_509 97760296a855c4c1b15a8efc2a41850b 317 Pfam PF03741 Integral membrane protein TerC family 64 263 1.4E-49 T 18-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TWT_509 97760296a855c4c1b15a8efc2a41850b 317 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 309 1.6E-84 T 18-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TWT_308 7b0f8a9f299e428d3834246489b97c02 291 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 52 270 4.6E-59 T 18-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 TWT_308 7b0f8a9f299e428d3834246489b97c02 291 Gene3D G3DSA:3.40.50.1360 45 284 2.6E-68 T 18-10-2018 TWT_308 7b0f8a9f299e428d3834246489b97c02 291 SUPERFAMILY SSF100950 46 283 1.0E-55 T 18-10-2018 IPR037171 NagB/RpiA transferase-like TWT_308 7b0f8a9f299e428d3834246489b97c02 291 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 50 280 3.8E-53 T 18-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 TWT_056 e75bcd66c818cabf1d9545c632faba7d 323 SUPERFAMILY SSF53807 53 312 3.6E-41 T 18-10-2018 TWT_056 e75bcd66c818cabf1d9545c632faba7d 323 Gene3D G3DSA:3.40.50.1980 32 168 9.2E-35 T 18-10-2018 TWT_056 e75bcd66c818cabf1d9545c632faba7d 323 Gene3D G3DSA:3.40.50.1980 172 321 1.4E-26 T 18-10-2018 TWT_056 e75bcd66c818cabf1d9545c632faba7d 323 Pfam PF01497 Periplasmic binding protein 54 289 8.1E-20 T 18-10-2018 IPR002491 ABC transporter periplasmic binding domain TWT_521 2ad4c62ac5a5d97803f89b9d09ea0e1b 203 Gene3D G3DSA:1.20.1260.10 40 202 7.6E-12 T 18-10-2018 IPR012347 Ferritin-like TWT_717 fed2be2e9541efce2de3ec0eb4a0d95c 404 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 18-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TWT_717 fed2be2e9541efce2de3ec0eb4a0d95c 404 Gene3D G3DSA:3.90.1150.10 27 389 2.4E-124 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_717 fed2be2e9541efce2de3ec0eb4a0d95c 404 Pfam PF00155 Aminotransferase class I and II 34 381 2.6E-67 T 18-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TWT_717 fed2be2e9541efce2de3ec0eb4a0d95c 404 SUPERFAMILY SSF53383 5 394 7.18E-106 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_717 fed2be2e9541efce2de3ec0eb4a0d95c 404 Gene3D G3DSA:3.40.640.10 65 284 2.4E-124 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 PIRSF PIRSF006468 3 360 6.8E-123 T 18-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 Gene3D G3DSA:3.30.470.10 29 354 6.8E-115 T 18-10-2018 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 Gene3D G3DSA:3.20.10.10 175 341 6.8E-115 T 18-10-2018 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 Pfam PF01063 Amino-transferase class IV 74 317 1.7E-29 T 18-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 ProSitePatterns PS00770 Aminotransferases class-IV signature. 236 266 - T 18-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 SUPERFAMILY SSF56752 11 356 3.53E-96 T 18-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TWT_208 7de7fd80db17b1870181f1cd571e555f 361 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 357 1.8E-101 T 18-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 Pfam PF00005 ABC transporter 33 170 3.5E-22 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 SUPERFAMILY SSF52540 17 238 3.19E-41 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 SUPERFAMILY SSF52540 267 513 1.25E-39 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 Gene3D G3DSA:3.40.50.300 8 253 1.2E-47 T 18-10-2018 TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 SMART SM00382 296 511 2.6E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 SMART SM00382 41 225 9.6E-13 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_408 abf0c64bf49f78bae4cfe9d8911375e0 515 Pfam PF00005 ABC transporter 288 462 4.2E-20 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 SUPERFAMILY SSF82679 36 140 7.32E-31 T 18-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 37 215 1.6E-49 T 18-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 SUPERFAMILY SSF50104 160 215 2.53E-15 T 18-10-2018 IPR008991 Translation protein SH3-like domain superfamily TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 Gene3D G3DSA:2.30.30.30 156 215 3.5E-21 T 18-10-2018 IPR014722 Ribosomal protein L2, domain 2 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 SMART SM00738 34 142 2.6E-30 T 18-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 PRINTS PR00338 Transcription termination factor NUSG signature 89 101 1.6E-13 T 18-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 PRINTS PR00338 Transcription termination factor NUSG signature 192 208 1.6E-13 T 18-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 PRINTS PR00338 Transcription termination factor NUSG signature 174 189 1.6E-13 T 18-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 SMART SM00739 162 189 8.1E-4 T 18-10-2018 IPR005824 KOW TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 Pfam PF02357 Transcription termination factor nusG 36 138 9.0E-22 T 18-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 34 216 20.083 T 18-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TWT_715 a1e3fd254da6df0cbc185d6fede59bea 217 Gene3D G3DSA:3.30.70.940 32 149 4.9E-33 T 18-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 SUPERFAMILY SSF55282 7 183 2.59E-67 T 18-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 Pfam PF00281 Ribosomal protein L5 28 84 2.4E-23 T 18-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 PIRSF PIRSF002161 3 183 1.0E-56 T 18-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 5 183 41.238 T 18-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 Pfam PF00673 ribosomal L5P family C-terminus 89 181 2.6E-36 T 18-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_542 89daeec0dbf80f3b1ab5a90b3815e852 183 Gene3D G3DSA:3.30.1440.10 4 183 4.0E-72 T 18-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_461 e44da4577f094ba8b18128582c2bc424 148 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 18-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_461 e44da4577f094ba8b18128582c2bc424 148 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.666 T 18-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_461 e44da4577f094ba8b18128582c2bc424 148 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.7E-31 T 18-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_461 e44da4577f094ba8b18128582c2bc424 148 Gene3D G3DSA:3.30.1320.10 1 115 7.7E-31 T 18-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_461 e44da4577f094ba8b18128582c2bc424 148 Pfam PF00886 Ribosomal protein S16 9 67 7.2E-24 T 18-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_461 e44da4577f094ba8b18128582c2bc424 148 SUPERFAMILY SSF54565 2 88 1.22E-32 T 18-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 97 119 - T 18-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 PIRSF PIRSF002181 1 141 7.9E-50 T 18-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 Pfam PF00572 Ribosomal protein L13 6 129 4.1E-53 T 18-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 Gene3D G3DSA:3.90.1180.10 2 137 1.5E-57 T 18-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 SUPERFAMILY SSF52161 4 132 1.16E-52 T 18-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 132 1.5E-57 T 18-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_144 cef696b463e6cf0cf2fb378dd1d9be1b 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 7 138 27.904 T 18-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 Gene3D G3DSA:3.30.565.10 321 475 5.0E-35 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF55874 306 470 1.83E-38 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 Gene3D G3DSA:1.20.1480.50 155 244 9.3E-7 T 18-10-2018 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF158472 191 238 3.53E-5 T 18-10-2018 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00304 188 241 1.1E-5 T 18-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 468 2.5E-23 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF47384 233 314 1.24E-16 T 18-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00387 358 470 1.9E-33 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 Gene3D G3DSA:1.10.287.130 245 316 4.8E-20 T 18-10-2018 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 315 3.5E-14 T 18-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00388 249 316 4.9E-16 T 18-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 3.4E-14 T 18-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 3.4E-14 T 18-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 3.4E-14 T 18-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TWT_046 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 3.4E-14 T 18-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TWT_505 dee602378e3b090e652479f479ae770d 347 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 100 111 - T 18-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 Gene3D G3DSA:3.30.1490.20 148 220 6.5E-55 T 18-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TWT_505 dee602378e3b090e652479f479ae770d 347 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 2 342 32.97 T 18-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 Pfam PF07478 D-ala D-ala ligase C-terminus 140 338 2.3E-47 T 18-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 SUPERFAMILY SSF56059 133 333 4.47E-36 T 18-10-2018 TWT_505 dee602378e3b090e652479f479ae770d 347 SUPERFAMILY SSF52440 3 132 1.92E-30 T 18-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TWT_505 dee602378e3b090e652479f479ae770d 347 Gene3D G3DSA:3.30.470.20 123 337 6.5E-55 T 18-10-2018 TWT_505 dee602378e3b090e652479f479ae770d 347 PIRSF PIRSF039102 1 347 1.1E-85 T 18-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 287 314 - T 18-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 Gene3D G3DSA:3.40.50.20 1 122 8.5E-29 T 18-10-2018 TWT_505 dee602378e3b090e652479f479ae770d 347 Pfam PF01820 D-ala D-ala ligase N-terminus 4 123 2.7E-25 T 18-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_505 dee602378e3b090e652479f479ae770d 347 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 3 341 4.3E-81 T 18-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_124 3ed3fc4ec21a10c7dd583c34441e28e3 853 Gene3D G3DSA:3.90.550.10 9 216 2.0E-20 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_124 3ed3fc4ec21a10c7dd583c34441e28e3 853 SUPERFAMILY SSF53448 12 258 6.0E-24 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 SUPERFAMILY SSF52374 3 174 9.38E-32 T 18-10-2018 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 Gene3D G3DSA:3.40.50.620 1 174 4.3E-43 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 1.5E-13 T 18-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 1.5E-13 T 18-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 60 1.2E-13 T 18-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 169 1.2E-38 T 18-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 176 25.392 T 18-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TWT_565 50e64db7e5f8681b5cd15a93e6e3f059 176 Pfam PF01467 Cytidylyltransferase-like 8 151 2.2E-13 T 18-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TWT_337 adc006f6399d51ef9f3066b520dd3b01 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 7.7E-72 T 18-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TWT_337 adc006f6399d51ef9f3066b520dd3b01 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 1.2E-216 T 18-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TWT_337 adc006f6399d51ef9f3066b520dd3b01 473 SUPERFAMILY SSF101960 39 470 5.23E-136 T 18-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.8E-5 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.8E-5 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.8E-5 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 SUPERFAMILY SSF51735 11 155 2.9E-24 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 Pfam PF00106 short chain dehydrogenase 17 148 7.8E-16 T 18-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TWT_321 2bb4da0db4b37bd4e2391d9e76dc0f56 258 Gene3D G3DSA:3.40.50.720 9 178 4.3E-23 T 18-10-2018 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 18-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 230 456 1.9E-70 T 18-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 SUPERFAMILY SSF47005 150 192 3.79E-10 T 18-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 SUPERFAMILY SSF52777 229 456 8.53E-75 T 18-10-2018 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Pfam PF00364 Biotin-requiring enzyme 4 76 7.0E-18 T 18-10-2018 IPR000089 Biotin/lipoyl attachment TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Pfam PF02817 e3 binding domain 157 191 3.5E-12 T 18-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Gene3D G3DSA:3.30.559.10 216 460 1.6E-80 T 18-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Gene3D G3DSA:2.40.50.100 1 97 3.2E-22 T 18-10-2018 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 SUPERFAMILY SSF51230 2 84 1.44E-22 T 18-10-2018 IPR011053 Single hybrid motif TWT_503 bc9177d09635c00ce8081ab0984ae661 461 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 4 458 1.2E-144 T 18-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 TWT_503 bc9177d09635c00ce8081ab0984ae661 461 Gene3D G3DSA:4.10.320.10 157 199 5.3E-13 T 18-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TWT_204 9131d543db80edb183f57c8a57289244 569 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 30 568 1.2E-212 T 18-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_204 9131d543db80edb183f57c8a57289244 569 SUPERFAMILY SSF143975 12 393 2.35E-131 T 18-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_204 9131d543db80edb183f57c8a57289244 569 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 480 491 - T 18-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_204 9131d543db80edb183f57c8a57289244 569 Gene3D G3DSA:3.50.30.80 394 542 3.1E-50 T 18-10-2018 TWT_204 9131d543db80edb183f57c8a57289244 569 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 134 144 - T 18-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_204 9131d543db80edb183f57c8a57289244 569 SUPERFAMILY SSF52016 394 568 5.96E-53 T 18-10-2018 TWT_204 9131d543db80edb183f57c8a57289244 569 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 16 569 44.051 T 18-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_204 9131d543db80edb183f57c8a57289244 569 Pfam PF00920 Dehydratase family 46 567 1.5E-206 T 18-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TWT_347 3b21c803354ea9409af47569f139794f 466 Gene3D G3DSA:3.40.50.620 1 306 1.2E-108 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_347 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 3.7E-25 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 3.7E-25 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 3.7E-25 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 3.7E-25 T 18-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 457 2.1E-125 T 18-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 466 32.833 T 18-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 314 1.4E-103 T 18-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 Pfam PF09190 DALR domain 349 400 1.7E-5 T 18-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TWT_347 3b21c803354ea9409af47569f139794f 466 SUPERFAMILY SSF47323 335 457 1.44E-18 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_347 3b21c803354ea9409af47569f139794f 466 SUPERFAMILY SSF52374 19 315 1.66E-76 T 18-10-2018 TWT_347 3b21c803354ea9409af47569f139794f 466 Gene3D G3DSA:1.20.120.640 307 460 1.4E-19 T 18-10-2018 TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 204 261 2.3E-16 T 18-10-2018 IPR017703 YgfZ/GcvT conserved site TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 Gene3D G3DSA:3.30.1360.120 11 144 8.2E-9 T 18-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 236 323 3.1E-9 T 18-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 SUPERFAMILY SSF103025 29 251 8.63E-36 T 18-10-2018 TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 Gene3D G3DSA:3.30.1360.120 187 325 6.8E-25 T 18-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TWT_656 0e2f9f14ab994d1bb84791ff2a262515 344 SUPERFAMILY SSF101790 255 328 1.64E-6 T 18-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TWT_255 a0f67325139066e5bab24e660e0c862f 933 PIRSF PIRSF000156 75 931 0.0 T 18-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TWT_255 a0f67325139066e5bab24e660e0c862f 933 PIRSF PIRSF000156 5 79 6.2E-7 T 18-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TWT_255 a0f67325139066e5bab24e660e0c862f 933 SUPERFAMILY SSF52518 516 749 1.18E-78 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_255 a0f67325139066e5bab24e660e0c862f 933 SUPERFAMILY SSF52922 753 929 1.92E-45 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_255 a0f67325139066e5bab24e660e0c862f 933 Gene3D G3DSA:3.40.50.970 98 512 1.8E-112 T 18-10-2018 TWT_255 a0f67325139066e5bab24e660e0c862f 933 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 92 927 0.0 T 18-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TWT_255 a0f67325139066e5bab24e660e0c862f 933 SUPERFAMILY SSF52518 99 507 4.47E-114 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_255 a0f67325139066e5bab24e660e0c862f 933 Gene3D G3DSA:3.40.50.970 513 755 1.3E-85 T 18-10-2018 TWT_255 a0f67325139066e5bab24e660e0c862f 933 Gene3D G3DSA:3.40.50.920 757 931 1.8E-52 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_255 a0f67325139066e5bab24e660e0c862f 933 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 142 334 1.7E-10 T 18-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_472 8ef041988e268a305d444c263a04a0d1 82 SUPERFAMILY SSF110324 2 78 1.74E-31 T 18-10-2018 TWT_472 8ef041988e268a305d444c263a04a0d1 82 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 2.0E-17 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 82 25.362 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 18-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_472 8ef041988e268a305d444c263a04a0d1 82 Gene3D G3DSA:2.40.50.1030 5 80 2.5E-26 T 18-10-2018 TWT_472 8ef041988e268a305d444c263a04a0d1 82 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 80 9.8E-35 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 Pfam PF01016 Ribosomal L27 protein 2 80 3.5E-36 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.5E-36 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.5E-36 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_472 8ef041988e268a305d444c263a04a0d1 82 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.5E-36 T 18-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_061 fd16931a816089a54af6d53f277497c9 115 Pfam PF01022 Bacterial regulatory protein, arsR family 40 83 1.8E-13 T 18-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TWT_061 fd16931a816089a54af6d53f277497c9 115 Gene3D G3DSA:1.10.10.10 16 115 1.3E-27 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_061 fd16931a816089a54af6d53f277497c9 115 SUPERFAMILY SSF46785 17 112 4.2E-24 T 18-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TWT_061 fd16931a816089a54af6d53f277497c9 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 2.0E-13 T 18-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TWT_061 fd16931a816089a54af6d53f277497c9 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 2.0E-13 T 18-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TWT_061 fd16931a816089a54af6d53f277497c9 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 80 95 2.0E-13 T 18-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TWT_061 fd16931a816089a54af6d53f277497c9 115 SMART SM00418 31 109 1.2E-24 T 18-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TWT_078 a6ed0f36d3e26e3edae17a44e50ffb99 145 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 87 134 9.9E-9 T 18-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TWT_078 a6ed0f36d3e26e3edae17a44e50ffb99 145 Pfam PF12823 Domain of unknown function (DUF3817) 27 134 9.4E-21 T 18-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TWT_636 1a23f256d9ed251ee0f2876d0546cd5a 187 SUPERFAMILY SSF53335 1 183 3.29E-37 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_636 1a23f256d9ed251ee0f2876d0546cd5a 187 PIRSF PIRSF004553 1 186 7.8E-45 T 18-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TWT_636 1a23f256d9ed251ee0f2876d0546cd5a 187 Gene3D G3DSA:3.40.50.150 1 186 2.8E-47 T 18-10-2018 TWT_636 1a23f256d9ed251ee0f2876d0546cd5a 187 Pfam PF03602 Conserved hypothetical protein 95 1 183 2.2E-41 T 18-10-2018 TWT_636 1a23f256d9ed251ee0f2876d0546cd5a 187 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 3.6E-35 T 18-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TWT_487 3474b4073ca79e73e6e843d7e0f7376e 146 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 3 141 28.634 T 18-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TWT_487 3474b4073ca79e73e6e843d7e0f7376e 146 Gene3D G3DSA:2.70.40.10 1 144 1.2E-46 T 18-10-2018 IPR036157 dUTPase-like superfamily TWT_487 3474b4073ca79e73e6e843d7e0f7376e 146 Pfam PF00692 dUTPase 13 140 6.3E-34 T 18-10-2018 IPR029054 dUTPase-like TWT_487 3474b4073ca79e73e6e843d7e0f7376e 146 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 141 2.0E-44 T 18-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TWT_487 3474b4073ca79e73e6e843d7e0f7376e 146 SUPERFAMILY SSF51283 6 141 6.67E-43 T 18-10-2018 IPR036157 dUTPase-like superfamily TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 SUPERFAMILY SSF53067 1 98 5.96E-16 T 18-10-2018 TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 342 7.7E-59 T 18-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 Gene3D G3DSA:3.30.420.40 1 137 4.4E-18 T 18-10-2018 TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 Pfam PF00814 Glycoprotease family 36 140 1.8E-11 T 18-10-2018 IPR000905 Gcp-like domain TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 Gene3D G3DSA:3.40.630.30 360 501 2.0E-34 T 18-10-2018 TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 SUPERFAMILY SSF55729 362 501 2.7E-30 T 18-10-2018 IPR016181 Acyl-CoA N-acyltransferase TWT_592 57c037fbafe48aff6f0cfc18263e7afe 501 Pfam PF00583 Acetyltransferase (GNAT) family 372 479 9.0E-16 T 18-10-2018 IPR000182 GNAT domain TWT_603 e8fa4d53fedbc940bd62e09487fdfd8a 364 SUPERFAMILY SSF47240 8 76 3.95E-6 T 18-10-2018 IPR009078 Ferritin-like superfamily TWT_603 e8fa4d53fedbc940bd62e09487fdfd8a 364 Pfam PF01988 VIT family 130 357 1.7E-61 T 18-10-2018 IPR008217 Ccc1 family TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 SUPERFAMILY SSF52540 2 182 1.98E-33 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 Gene3D G3DSA:3.40.50.300 1 186 1.1E-50 T 18-10-2018 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 ProSitePatterns PS00113 Adenylate kinase signature. 77 88 - T 18-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 Hamap MF_00235 Adenylate kinase [adk]. 1 182 34.435 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 32 46 4.0E-25 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 146 160 4.0E-25 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 129 144 4.0E-25 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 4 17 4.0E-25 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 77 93 4.0E-25 T 18-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TWT_534 b3bc5b5679291ae69c6890b050fd2551 186 Pfam PF00406 Adenylate kinase 5 159 4.4E-36 T 18-10-2018 TWT_267 65e20c815f17d72202589f6c037277d6 183 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 18-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 TWT_267 65e20c815f17d72202589f6c037277d6 183 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 31.825 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_267 65e20c815f17d72202589f6c037277d6 183 Gene3D G3DSA:3.30.420.10 1 159 3.5E-40 T 18-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TWT_267 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 2.6E-21 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_267 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 2.6E-21 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_267 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 2.6E-21 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_267 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.6E-21 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_267 65e20c815f17d72202589f6c037277d6 183 SUPERFAMILY SSF53098 1 156 3.49E-39 T 18-10-2018 IPR012337 Ribonuclease H-like superfamily TWT_267 65e20c815f17d72202589f6c037277d6 183 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 2.4E-33 T 18-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TWT_023 fa704526d1eaa9166405aada31d3073d 525 Pfam PF01039 Carboxyl transferase domain 33 523 6.4E-189 T 18-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TWT_023 fa704526d1eaa9166405aada31d3073d 525 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 8.9E-6 T 18-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TWT_023 fa704526d1eaa9166405aada31d3073d 525 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 8.9E-6 T 18-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TWT_023 fa704526d1eaa9166405aada31d3073d 525 Gene3D G3DSA:3.90.226.10 1 261 5.1E-92 T 18-10-2018 TWT_023 fa704526d1eaa9166405aada31d3073d 525 Gene3D G3DSA:3.90.226.10 262 525 9.7E-87 T 18-10-2018 TWT_023 fa704526d1eaa9166405aada31d3073d 525 SUPERFAMILY SSF52096 13 261 2.57E-75 T 18-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TWT_023 fa704526d1eaa9166405aada31d3073d 525 SUPERFAMILY SSF52096 230 525 5.62E-84 T 18-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TWT_651 45e7376422f379168c01728e088c96be 186 Gene3D G3DSA:3.40.50.1470 1 179 4.9E-55 T 18-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TWT_651 45e7376422f379168c01728e088c96be 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 168 1.6E-47 T 18-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TWT_651 45e7376422f379168c01728e088c96be 186 SUPERFAMILY SSF53178 3 175 4.58E-54 T 18-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TWT_651 45e7376422f379168c01728e088c96be 186 Pfam PF01195 Peptidyl-tRNA hydrolase 5 166 2.9E-48 T 18-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TWT_651 45e7376422f379168c01728e088c96be 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 171 30.256 T 18-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TWT_651 45e7376422f379168c01728e088c96be 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 18-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 11 335 35.381 T 18-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 Pfam PF00579 tRNA synthetases class I (W and Y) 10 279 1.6E-65 T 18-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 30 - T 18-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 75 94 6.8E-25 T 18-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 25 41 6.8E-25 T 18-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 6.8E-25 T 18-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 6.8E-25 T 18-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 Gene3D G3DSA:3.40.50.620 14 333 7.9E-116 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 10 333 1.8E-94 T 18-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 Gene3D G3DSA:1.10.240.10 192 302 7.9E-116 T 18-10-2018 TWT_686 e82f87b0f99f89b81ae085c469d5bd02 335 SUPERFAMILY SSF52374 13 333 4.41E-85 T 18-10-2018 TWT_111 5d0640a7d9c86ae36bac738e1e7fadab 428 Pfam PF00501 AMP-binding enzyme 88 327 7.1E-28 T 18-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TWT_111 5d0640a7d9c86ae36bac738e1e7fadab 428 Gene3D G3DSA:3.40.50.12780 22 320 2.2E-37 T 18-10-2018 TWT_111 5d0640a7d9c86ae36bac738e1e7fadab 428 SUPERFAMILY SSF56801 92 425 3.27E-53 T 18-10-2018 TWT_111 5d0640a7d9c86ae36bac738e1e7fadab 428 Gene3D G3DSA:3.30.300.30 323 426 1.2E-10 T 18-10-2018 TWT_394 23330084833e2d93a24e0472a515a7b9 391 Pfam PF01612 3'-5' exonuclease 19 182 5.2E-26 T 18-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TWT_394 23330084833e2d93a24e0472a515a7b9 391 Gene3D G3DSA:3.30.420.10 5 206 1.9E-53 T 18-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TWT_394 23330084833e2d93a24e0472a515a7b9 391 Pfam PF00570 HRDC domain 223 291 6.8E-12 T 18-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TWT_394 23330084833e2d93a24e0472a515a7b9 391 SMART SM00341 220 301 0.0011 T 18-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TWT_394 23330084833e2d93a24e0472a515a7b9 391 SMART SM00474 16 183 4.7E-18 T 18-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TWT_394 23330084833e2d93a24e0472a515a7b9 391 Gene3D G3DSA:1.10.150.80 306 390 9.2E-9 T 18-10-2018 TWT_394 23330084833e2d93a24e0472a515a7b9 391 SUPERFAMILY SSF53098 18 210 1.41E-46 T 18-10-2018 IPR012337 Ribonuclease H-like superfamily TWT_394 23330084833e2d93a24e0472a515a7b9 391 SUPERFAMILY SSF47819 217 305 7.48E-12 T 18-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TWT_394 23330084833e2d93a24e0472a515a7b9 391 Gene3D G3DSA:1.10.150.80 213 304 3.0E-11 T 18-10-2018 TWT_263 38d659eb5b590006a6d7a56a28b90300 178 Gene3D G3DSA:3.30.428.10 6 177 4.7E-48 T 18-10-2018 IPR036265 HIT-like superfamily TWT_263 38d659eb5b590006a6d7a56a28b90300 178 SUPERFAMILY SSF54197 16 171 1.86E-39 T 18-10-2018 IPR036265 HIT-like superfamily TWT_263 38d659eb5b590006a6d7a56a28b90300 178 Pfam PF01230 HIT domain 51 142 2.1E-10 T 18-10-2018 IPR001310 Histidine triad (HIT) protein TWT_198 3278f4b175c2deca833086824bfecfe2 376 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 33.42 T 18-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TWT_198 3278f4b175c2deca833086824bfecfe2 376 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 18-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TWT_198 3278f4b175c2deca833086824bfecfe2 376 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 363 2.6E-129 T 18-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TWT_198 3278f4b175c2deca833086824bfecfe2 376 Pfam PF00472 RF-1 domain 229 336 1.5E-35 T 18-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TWT_198 3278f4b175c2deca833086824bfecfe2 376 SMART SM00937 84 194 1.8E-35 T 18-10-2018 IPR005139 Peptide chain release factor GO:0006415 TWT_198 3278f4b175c2deca833086824bfecfe2 376 Gene3D G3DSA:3.30.160.20 225 319 8.1E-83 T 18-10-2018 TWT_198 3278f4b175c2deca833086824bfecfe2 376 Gene3D G3DSA:1.20.58.410 1 114 5.3E-17 T 18-10-2018 TWT_198 3278f4b175c2deca833086824bfecfe2 376 SUPERFAMILY SSF75620 29 366 2.49E-110 T 18-10-2018 TWT_198 3278f4b175c2deca833086824bfecfe2 376 Pfam PF03462 PCRF domain 30 219 2.2E-48 T 18-10-2018 IPR005139 Peptide chain release factor GO:0006415 TWT_198 3278f4b175c2deca833086824bfecfe2 376 Gene3D G3DSA:3.30.70.1660 129 357 8.1E-83 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 16 342 1.2E-81 T 18-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 SUPERFAMILY SSF50249 343 425 5.65E-24 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 22 627 1.3E-154 T 18-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 SMART SM00532 13 474 1.1E-152 T 18-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 PIRSF PIRSF001604 5 634 7.3E-199 T 18-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 SUPERFAMILY SSF56091 14 341 1.69E-87 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 125 154 - T 18-10-2018 IPR018239 NAD-dependent DNA ligase, active site TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Pfam PF12826 Helix-hairpin-helix motif 559 622 3.4E-19 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Gene3D G3DSA:3.30.470.90 79 343 5.6E-76 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Gene3D G3DSA:1.10.150.20 553 633 8.7E-23 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Hamap MF_01588 DNA ligase [ligA]. 12 634 43.789 T 18-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 347 423 1.9E-29 T 18-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 SUPERFAMILY SSF47781 429 629 1.37E-40 T 18-10-2018 IPR010994 RuvA domain 2-like TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 356 371 - T 18-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Gene3D G3DSA:1.10.287.610 5 75 1.7E-10 T 18-10-2018 TWT_414 1b2f3197e02c6d665a850777bfe2ef78 634 Gene3D G3DSA:2.40.50.140 344 430 2.0E-29 T 18-10-2018 TWT_690 d1f35d155e638beed0461e9651b42295 211 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 24 209 2.4E-65 T 18-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TWT_690 d1f35d155e638beed0461e9651b42295 211 Pfam PF00925 GTP cyclohydrolase II 24 183 6.3E-61 T 18-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TWT_690 d1f35d155e638beed0461e9651b42295 211 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 20 211 35.726 T 18-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TWT_690 d1f35d155e638beed0461e9651b42295 211 Gene3D G3DSA:3.40.50.10990 15 184 5.4E-66 T 18-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TWT_690 d1f35d155e638beed0461e9651b42295 211 SUPERFAMILY SSF142695 22 187 1.96E-54 T 18-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 Pfam PF00814 Glycoprotease family 188 370 6.7E-48 T 18-10-2018 IPR000905 Gcp-like domain TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 Pfam PF00814 Glycoprotease family 23 122 1.1E-33 T 18-10-2018 IPR000905 Gcp-like domain TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 Gene3D G3DSA:3.30.420.40 3 165 3.0E-44 T 18-10-2018 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 SUPERFAMILY SSF53067 102 372 3.74E-33 T 18-10-2018 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 396 54.238 T 18-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 Gene3D G3DSA:3.30.420.40 184 357 1.7E-50 T 18-10-2018 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 SUPERFAMILY SSF53067 3 121 6.47E-29 T 18-10-2018 TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 9.8E-22 T 18-10-2018 IPR017861 Kae1/TsaD family TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 9.8E-22 T 18-10-2018 IPR017861 Kae1/TsaD family TWT_591 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 9.8E-22 T 18-10-2018 IPR017861 Kae1/TsaD family TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 10 67 1.1E-28 T 18-10-2018 IPR020784 Ribosomal protein L11, N-terminal TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 37 74 2.0E-16 T 18-10-2018 TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 SUPERFAMILY SSF46906 68 140 8.24E-23 T 18-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 SUPERFAMILY SSF54747 4 73 1.83E-29 T 18-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 Gene3D G3DSA:1.10.10.250 73 141 3.5E-25 T 18-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 6 141 29.013 T 18-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 Gene3D G3DSA:3.30.1550.10 3 72 2.6E-33 T 18-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.8E-19 T 18-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 SMART SM00649 10 141 1.6E-72 T 18-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TWT_714 a93d9f95a37f4429798affd83e74f9bc 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 4 140 1.6E-58 T 18-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 Gene3D G3DSA:3.40.1010.20 18 290 8.6E-104 T 18-10-2018 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 Gene3D G3DSA:3.40.50.11270 23 107 8.6E-104 T 18-10-2018 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 12 295 35.437 T 18-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 14 291 1.5E-91 T 18-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 Gene3D G3DSA:3.40.1010.20 108 204 8.6E-104 T 18-10-2018 TWT_642 a28eefb9963d8c80f7160322a76d84d8 322 Pfam PF02401 LytB protein 14 291 7.0E-84 T 18-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TWT_716 14d7827f511500d008ab86fbb7688a13 80 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 22 73 1.8E-12 T 18-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_716 14d7827f511500d008ab86fbb7688a13 80 Hamap MF_00422 Protein translocase subunit SecE [secE]. 19 74 11.04 T 18-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TWT_716 14d7827f511500d008ab86fbb7688a13 80 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 21 76 1.1E-10 T 18-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 TWT_716 14d7827f511500d008ab86fbb7688a13 80 Gene3D G3DSA:1.20.5.1030 17 75 3.4E-12 T 18-10-2018 IPR038379 SecE superfamily TWT_446 2116c8cf8abedf1ce261d49617e017f8 181 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 181 20.576 T 18-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TWT_446 2116c8cf8abedf1ce261d49617e017f8 181 SUPERFAMILY SSF55194 7 180 5.49E-48 T 18-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 TWT_446 2116c8cf8abedf1ce261d49617e017f8 181 Pfam PF01765 Ribosome recycling factor 20 179 4.6E-41 T 18-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TWT_446 2116c8cf8abedf1ce261d49617e017f8 181 Gene3D G3DSA:3.30.1360.40 31 105 5.1E-45 T 18-10-2018 TWT_446 2116c8cf8abedf1ce261d49617e017f8 181 Gene3D G3DSA:1.10.132.20 12 178 5.1E-45 T 18-10-2018 TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 SUPERFAMILY SSF50447 4 204 6.18E-72 T 18-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Pfam PF00297 Ribosomal protein L3 95 178 5.9E-18 T 18-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Gene3D G3DSA:2.40.50.620 32 88 7.4E-10 T 18-10-2018 TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 97 120 - T 18-10-2018 IPR019926 Ribosomal protein L3, conserved site TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 200 8.8E-78 T 18-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 203 36.625 T 18-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_554 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Gene3D G3DSA:2.40.30.10 117 206 9.4E-17 T 18-10-2018 TWT_436 5a6e56c4412708104e158749b2756493 454 SUPERFAMILY SSF52540 154 430 7.98E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_436 5a6e56c4412708104e158749b2756493 454 SUPERFAMILY SSF50249 117 190 9.42E-12 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_436 5a6e56c4412708104e158749b2756493 454 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 224 429 1.8E-15 T 18-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_436 5a6e56c4412708104e158749b2756493 454 Gene3D G3DSA:3.40.50.300 199 453 1.7E-64 T 18-10-2018 TWT_436 5a6e56c4412708104e158749b2756493 454 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 420 429 - T 18-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TWT_436 5a6e56c4412708104e158749b2756493 454 Gene3D G3DSA:2.40.50.140 70 195 1.3E-25 T 18-10-2018 TWT_436 5a6e56c4412708104e158749b2756493 454 Pfam PF07497 Rho termination factor, RNA-binding domain 118 190 1.1E-21 T 18-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 TWT_436 5a6e56c4412708104e158749b2756493 454 SMART SM00959 6 46 1.6E-5 T 18-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 Gene3D G3DSA:3.40.50.300 7 278 1.1E-71 T 18-10-2018 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 4 282 1.2E-65 T 18-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 3 295 23.964 T 18-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 Gene3D G3DSA:1.10.20.140 110 178 1.1E-71 T 18-10-2018 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 SUPERFAMILY SSF52540 6 144 5.31E-11 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 Pfam PF01715 IPP transferase 36 272 6.4E-59 T 18-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TWT_609 668efa5e5c70ac727179b4bb1c24c527 301 SUPERFAMILY SSF52540 4 296 2.0E-7 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_009 7523f6cc4b35bca46e6d9fec6223e57e 212 SUPERFAMILY SSF144091 13 188 3.4E-43 T 18-10-2018 TWT_009 7523f6cc4b35bca46e6d9fec6223e57e 212 Gene3D G3DSA:1.20.1540.10 11 192 1.9E-40 T 18-10-2018 IPR035952 Rhomboid-like superfamily TWT_009 7523f6cc4b35bca46e6d9fec6223e57e 212 Pfam PF01694 Rhomboid family 57 187 2.2E-31 T 18-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 SUPERFAMILY SSF46609 3 85 2.36E-33 T 18-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 3.5E-22 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.5E-22 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.5E-22 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 3.5E-22 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 3.5E-22 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 18-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 3.5E-31 T 18-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 SUPERFAMILY SSF54719 84 195 8.51E-38 T 18-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 191 4.6E-32 T 18-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 Gene3D G3DSA:2.40.500.20 85 201 1.2E-37 T 18-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 PIRSF PIRSF000349 1 200 6.1E-72 T 18-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_299 9813c3209cc6fa66d51dcdfbc3b77e8a 202 Gene3D G3DSA:1.10.287.990 21 84 1.2E-26 T 18-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TWT_571 29be3b62be39e9f8e7b65167ab60e83c 205 Gene3D G3DSA:3.40.50.150 3 204 4.5E-39 T 18-10-2018 TWT_571 29be3b62be39e9f8e7b65167ab60e83c 205 SUPERFAMILY SSF53335 34 203 9.8E-25 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_571 29be3b62be39e9f8e7b65167ab60e83c 205 Pfam PF01596 O-methyltransferase 28 202 2.5E-18 T 18-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Gene3D G3DSA:3.40.50.720 15 102 1.6E-24 T 18-10-2018 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Gene3D G3DSA:3.90.190.20 322 474 2.5E-45 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_229 36f43c918050b88f20767b3a87727fb5 475 SUPERFAMILY SSF51984 16 101 2.22E-21 T 18-10-2018 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Gene3D G3DSA:3.40.1190.10 103 321 1.5E-46 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 412 2.5E-18 T 18-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Pfam PF01225 Mur ligase family, catalytic domain 17 114 2.8E-18 T 18-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Pfam PF08245 Mur ligase middle domain 119 303 1.4E-14 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_229 36f43c918050b88f20767b3a87727fb5 475 SUPERFAMILY SSF53623 103 322 5.36E-44 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_229 36f43c918050b88f20767b3a87727fb5 475 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 467 1.1E-106 T 18-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_229 36f43c918050b88f20767b3a87727fb5 475 SUPERFAMILY SSF53244 323 470 1.58E-35 T 18-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TWT_229 36f43c918050b88f20767b3a87727fb5 475 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 14 473 30.772 T 18-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_539 570d75a16a9446bc1fc997994077a5de 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 2.9E-37 T 18-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_539 570d75a16a9446bc1fc997994077a5de 119 Gene3D G3DSA:3.30.420.100 4 118 7.0E-38 T 18-10-2018 TWT_539 570d75a16a9446bc1fc997994077a5de 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 118 1.0E-44 T 18-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_539 570d75a16a9446bc1fc997994077a5de 119 SUPERFAMILY SSF53137 6 117 1.26E-45 T 18-10-2018 TWT_539 570d75a16a9446bc1fc997994077a5de 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 5 119 26.186 T 18-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 Gene3D G3DSA:3.10.25.10 236 333 5.5E-19 T 18-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 Pfam PF00551 Formyl transferase 89 185 4.7E-22 T 18-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 Gene3D G3DSA:3.40.50.170 14 234 1.6E-45 T 18-10-2018 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 SUPERFAMILY SSF50486 234 331 5.02E-21 T 18-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 SUPERFAMILY SSF53328 20 232 1.7E-36 T 18-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_358 e5c6685aba7408810ea88cb7644a1c5a 334 Pfam PF02911 Formyl transferase, C-terminal domain 232 330 1.3E-22 T 18-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TWT_559 55f907d3fa775961c15aebd7ed9705ae 364 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 323 3.4E-42 T 18-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 PIRSF PIRSF004803 2 545 2.7E-183 T 18-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 SUPERFAMILY SSF56281 5 419 2.65E-87 T 18-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Hamap MF_01491 Ribonuclease J [rnj]. 1 545 36.458 T 18-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 6 542 3.0E-132 T 18-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 SMART SM00849 17 211 1.9E-22 T 18-10-2018 IPR001279 Metallo-beta-lactamase TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Pfam PF12706 Beta-lactamase superfamily domain 30 172 1.3E-12 T 18-10-2018 IPR001279 Metallo-beta-lactamase TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Gene3D G3DSA:3.40.50.10710 203 360 6.5E-163 T 18-10-2018 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 403 2.6E-5 T 18-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Gene3D G3DSA:3.10.20.580 443 545 1.5E-15 T 18-10-2018 TWT_615 b5360a2030f04ef31f2a2610fb60ac30 545 Gene3D G3DSA:3.60.15.10 6 431 6.5E-163 T 18-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TWT_806 ee1480a836a46eaf1b883ddb9d15cd4b 92 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 20 74 3.0E-27 T 18-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TWT_806 ee1480a836a46eaf1b883ddb9d15cd4b 92 Pfam PF01809 Haemolytic domain 8 72 3.6E-22 T 18-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TWT_806 ee1480a836a46eaf1b883ddb9d15cd4b 92 SMART SM01234 6 73 1.2E-28 T 18-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TWT_806 ee1480a836a46eaf1b883ddb9d15cd4b 92 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 10 77 1.3E-18 T 18-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TWT_806 ee1480a836a46eaf1b883ddb9d15cd4b 92 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 6 74 20.392 T 18-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TWT_175 db326fb1b4cb5913945fa9d1d32c3387 220 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_175 db326fb1b4cb5913945fa9d1d32c3387 220 Gene3D G3DSA:3.40.50.300 5 220 4.0E-49 T 18-10-2018 TWT_175 db326fb1b4cb5913945fa9d1d32c3387 220 SUPERFAMILY SSF52540 7 199 1.78E-47 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_175 db326fb1b4cb5913945fa9d1d32c3387 220 SMART SM00382 36 220 2.9E-5 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_175 db326fb1b4cb5913945fa9d1d32c3387 220 Pfam PF00005 ABC transporter 27 167 1.9E-27 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 58.733 T 18-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Gene3D G3DSA:3.30.43.10 2 67 2.1E-10 T 18-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 SUPERFAMILY SSF56176 5 192 3.48E-31 T 18-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Gene3D G3DSA:3.90.78.10 230 351 1.1E-31 T 18-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 205 347 1.3E-26 T 18-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Pfam PF01565 FAD binding domain 38 148 6.3E-18 T 18-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 Gene3D G3DSA:3.30.465.10 68 218 5.8E-31 T 18-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TWT_718 a4c94c4670b0f2327f6751b19df40cb5 351 SUPERFAMILY SSF56194 205 349 2.75E-27 T 18-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 303 318 2.0E-14 T 18-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 269 279 2.0E-14 T 18-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 130 145 2.0E-14 T 18-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 322 334 2.0E-14 T 18-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 Pfam PF11838 ERAP1-like C-terminal domain 527 826 1.5E-35 T 18-10-2018 IPR024571 ERAP1-like C-terminal domain TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 Pfam PF01433 Peptidase family M1 domain 218 451 1.9E-65 T 18-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 SUPERFAMILY SSF55486 216 460 1.83E-76 T 18-10-2018 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 836 0.0 T 18-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 Gene3D G3DSA:2.60.40.1730 16 204 6.3E-26 T 18-10-2018 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 Gene3D G3DSA:1.10.390.60 213 456 3.2E-74 T 18-10-2018 TWT_399 e4bcb045b35018e553c86c4daa10be7c 838 SUPERFAMILY SSF63737 9 204 1.44E-33 T 18-10-2018 TWT_139 54e5e448709b0509ca21f7bdbbc1c978 237 Pfam PF00005 ABC transporter 37 171 1.4E-28 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_139 54e5e448709b0509ca21f7bdbbc1c978 237 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_139 54e5e448709b0509ca21f7bdbbc1c978 237 SMART SM00382 37 216 1.0E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_139 54e5e448709b0509ca21f7bdbbc1c978 237 Gene3D G3DSA:3.40.50.300 11 236 1.5E-59 T 18-10-2018 TWT_139 54e5e448709b0509ca21f7bdbbc1c978 237 SUPERFAMILY SSF52540 18 223 1.61E-55 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 SUPERFAMILY SSF46626 152 244 4.95E-22 T 18-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 Gene3D G3DSA:1.10.760.10 169 250 1.3E-11 T 18-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 Pfam PF00034 Cytochrome c 77 152 1.5E-9 T 18-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 Gene3D G3DSA:1.10.760.10 30 154 1.7E-15 T 18-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 PIRSF PIRSF000007 10 287 1.9E-123 T 18-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 SUPERFAMILY SSF46626 43 155 9.87E-20 T 18-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TWT_247 307f0677a09f9401b61e3d27dcc486e2 288 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 172 242 2.2E-10 T 18-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_743 df6b81fe4bbe73f6653364c7bdb9a3bd 214 Pfam PF00156 Phosphoribosyl transferase domain 92 188 9.8E-9 T 18-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TWT_743 df6b81fe4bbe73f6653364c7bdb9a3bd 214 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 214 24.818 T 18-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_743 df6b81fe4bbe73f6653364c7bdb9a3bd 214 SUPERFAMILY SSF53271 29 209 8.78E-37 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_743 df6b81fe4bbe73f6653364c7bdb9a3bd 214 Gene3D G3DSA:3.40.50.2020 25 208 1.3E-46 T 18-10-2018 TWT_743 df6b81fe4bbe73f6653364c7bdb9a3bd 214 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 44 206 3.6E-37 T 18-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 Pfam PF00005 ABC transporter 340 473 1.8E-17 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 Pfam PF00005 ABC transporter 21 190 1.5E-26 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 Gene3D G3DSA:3.40.50.300 286 547 8.0E-59 T 18-10-2018 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 SUPERFAMILY SSF52540 13 242 3.22E-48 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 SMART SM00382 348 517 1.3E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 SMART SM00382 30 251 6.0E-12 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 Gene3D G3DSA:3.40.50.300 5 284 6.0E-75 T 18-10-2018 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 Pfam PF12848 ABC transporter 229 296 4.5E-11 T 18-10-2018 IPR032781 ABC-transporter extension domain TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 552 1.4E-255 T 18-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 TWT_401 5e0b141bf5f0c414e8bd6cce9965b6bb 556 SUPERFAMILY SSF52540 307 513 1.93E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 SMART SM00382 199 387 0.0053 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 SUPERFAMILY SSF52540 181 427 3.16E-49 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 Pfam PF00772 DnaB-like helicase N terminal domain 6 108 1.4E-30 T 18-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 7 435 1.1E-154 T 18-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 Pfam PF03796 DnaB-like helicase C terminal domain 182 434 3.8E-101 T 18-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 Gene3D G3DSA:3.40.50.300 165 440 1.5E-100 T 18-10-2018 TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 SUPERFAMILY SSF48024 5 115 2.22E-33 T 18-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 TWT_738 852c2e80b4e58765afcd7fc0ada69fef 441 Gene3D G3DSA:1.10.860.10 1 163 7.8E-46 T 18-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 94 167 9.9E-11 T 18-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 PIRSF PIRSF006092 11 170 4.8E-28 T 18-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 30 61 - T 18-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 SUPERFAMILY SSF46557 17 89 1.05E-20 T 18-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 SUPERFAMILY SSF54534 94 167 1.83E-8 T 18-10-2018 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 Pfam PF03449 Transcription elongation factor, N-terminal 18 87 2.5E-24 T 18-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 Gene3D G3DSA:3.10.50.30 93 171 1.1E-6 T 18-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TWT_680 f01a808c2e5ace2a0e287f6f8af8b45e 172 Gene3D G3DSA:1.10.287.180 15 87 5.1E-23 T 18-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 361 39.03 T 18-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Gene3D G3DSA:1.10.1740.10 277 367 9.7E-24 T 18-10-2018 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 56 362 2.7E-100 T 18-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 PIRSF PIRSF006205 1 368 6.3E-132 T 18-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 51 5.7E-10 T 18-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 54 108 2.8E-15 T 18-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 SUPERFAMILY SSF69055 266 364 1.03E-19 T 18-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 121 202 1.1E-33 T 18-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 SUPERFAMILY SSF55347 102 235 1.34E-51 T 18-10-2018 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Gene3D G3DSA:3.40.50.720 52 125 2.0E-20 T 18-10-2018 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Gene3D G3DSA:3.40.50.720 1 51 5.0E-11 T 18-10-2018 TWT_089 62ee78d61865eccebf37ce5ae1927040 368 SUPERFAMILY SSF51735 2 125 5.05E-28 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_089 62ee78d61865eccebf37ce5ae1927040 368 Pfam PF13288 DXP reductoisomerase C-terminal domain 235 356 1.7E-28 T 18-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF00013 KH domain 597 654 9.1E-12 T 18-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 301 357 7.9E-5 T 18-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 8 736 25.912 T 18-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF55666 488 587 3.21E-22 T 18-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF00575 S1 RNA binding domain 664 730 7.8E-9 T 18-10-2018 IPR003029 S1 domain GO:0003676 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 3 736 0.0 T 18-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Gene3D G3DSA:3.30.230.70 2 254 7.4E-79 T 18-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF46915 260 364 1.02E-10 T 18-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Gene3D G3DSA:3.30.230.70 263 591 2.9E-91 T 18-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF55666 151 260 7.32E-22 T 18-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF54791 589 700 8.01E-20 T 18-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF03725 3' exoribonuclease family, domain 2 497 570 4.1E-5 T 18-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF01138 3' exoribonuclease family, domain 1 362 494 5.4E-14 T 18-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Pfam PF01138 3' exoribonuclease family, domain 1 19 150 4.1E-16 T 18-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SMART SM00316 663 737 2.2E-12 T 18-10-2018 IPR022967 RNA-binding domain, S1 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 Gene3D G3DSA:2.40.50.140 592 719 4.1E-44 T 18-10-2018 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF54211 7 150 6.58E-44 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 16 735 2.6E-239 T 18-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SMART SM00322 593 658 1.9E-13 T 18-10-2018 IPR004087 K Homology domain GO:0003676 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 PIRSF PIRSF005499 6 738 3.0E-260 T 18-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TWT_421 3fa6e387f9d178292a5e23ec001f75ac 738 SUPERFAMILY SSF54211 335 506 8.6E-40 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_597 09889d0d218f6129a056182b0c03aa5d 398 SUPERFAMILY SSF56112 25 194 6.56E-20 T 18-10-2018 IPR011009 Protein kinase-like domain superfamily TWT_597 09889d0d218f6129a056182b0c03aa5d 398 Gene3D G3DSA:1.10.510.10 17 197 7.2E-13 T 18-10-2018 TWT_155 e02e601e9f63881202524647e053b050 211 Pfam PF02592 Putative vitamin uptake transporter 43 204 2.6E-30 T 18-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TWT_155 e02e601e9f63881202524647e053b050 211 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 19 210 6.0E-23 T 18-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TWT_155 e02e601e9f63881202524647e053b050 211 Hamap MF_02088 Probable queuosine precursor transporter. 6 211 12.871 T 18-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 SMART SM00228 326 402 6.7E-17 T 18-10-2018 IPR001478 PDZ domain GO:0005515 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 Gene3D G3DSA:2.30.42.10 323 418 1.2E-23 T 18-10-2018 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 Gene3D G3DSA:2.40.10.120 102 321 2.3E-61 T 18-10-2018 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 Pfam PF13365 Trypsin-like peptidase domain 138 284 5.5E-32 T 18-10-2018 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 Pfam PF13180 PDZ domain 326 411 8.9E-16 T 18-10-2018 IPR001478 PDZ domain GO:0005515 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 SUPERFAMILY SSF50156 297 415 1.97E-23 T 18-10-2018 IPR036034 PDZ superfamily GO:0005515 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 213 237 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 277 294 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 360 372 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 173 193 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 255 272 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 PRINTS PR00834 HtrA/DegQ protease family signature 147 159 1.4E-39 T 18-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TWT_625 e0fa3148d94c061cb464fb189fe45979 420 SUPERFAMILY SSF50494 114 318 1.79E-50 T 18-10-2018 IPR009003 Peptidase S1, PA clan TWT_637 7f84d4438a548e902ed8174db0023830 121 Pfam PF01597 Glycine cleavage H-protein 7 120 1.2E-31 T 18-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TWT_637 7f84d4438a548e902ed8174db0023830 121 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 120 35.456 T 18-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TWT_637 7f84d4438a548e902ed8174db0023830 121 SUPERFAMILY SSF51230 5 120 1.78E-31 T 18-10-2018 IPR011053 Single hybrid motif TWT_637 7f84d4438a548e902ed8174db0023830 121 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 18-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TWT_637 7f84d4438a548e902ed8174db0023830 121 Gene3D G3DSA:2.40.50.100 2 121 1.3E-36 T 18-10-2018 TWT_032 f16e05feec8198f376b600550255d5fa 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 2.4E-135 T 18-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TWT_032 f16e05feec8198f376b600550255d5fa 292 Pfam PF00483 Nucleotidyl transferase 2 235 8.1E-63 T 18-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TWT_032 f16e05feec8198f376b600550255d5fa 292 Gene3D G3DSA:3.90.550.10 1 289 6.2E-77 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_032 f16e05feec8198f376b600550255d5fa 292 SUPERFAMILY SSF53448 2 285 3.38E-81 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_564 afb29a03e4673bfa901649f38401ac3d 251 Gene3D G3DSA:2.40.260.10 58 247 2.5E-37 T 18-10-2018 IPR023365 Sortase domain superfamily TWT_564 afb29a03e4673bfa901649f38401ac3d 251 SUPERFAMILY SSF63817 93 237 1.12E-25 T 18-10-2018 IPR023365 Sortase domain superfamily TWT_564 afb29a03e4673bfa901649f38401ac3d 251 Pfam PF04203 Sortase family 102 234 6.0E-24 T 18-10-2018 IPR005754 Sortase family TWT_077 dd3e8581f15e8e09b37bd90cd433baac 246 Pfam PF02104 SURF1 family 28 223 7.7E-7 T 18-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_211 c113b16b2878ad382089b5f15c482a58 197 Gene3D G3DSA:1.10.1760.20 7 196 9.4E-49 T 18-10-2018 TWT_211 c113b16b2878ad382089b5f15c482a58 197 Pfam PF02632 BioY family 47 192 4.4E-31 T 18-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TWT_211 c113b16b2878ad382089b5f15c482a58 197 PIRSF PIRSF016661 11 197 1.6E-37 T 18-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TWT_199 709f323cf1c696993f0b8311728162a7 918 SUPERFAMILY SSF52540 1 221 2.32E-63 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_199 709f323cf1c696993f0b8311728162a7 918 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 3.1E-83 T 18-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TWT_199 709f323cf1c696993f0b8311728162a7 918 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_199 709f323cf1c696993f0b8311728162a7 918 SMART SM00382 28 215 1.9E-11 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_199 709f323cf1c696993f0b8311728162a7 918 Pfam PF00005 ABC transporter 19 166 7.5E-31 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_199 709f323cf1c696993f0b8311728162a7 918 Gene3D G3DSA:3.40.50.300 1 246 1.0E-60 T 18-10-2018 TWT_256 2e6901894ef00d83e1efd410a8fcb40e 156 Pfam PF00578 AhpC/TSA family 13 135 3.2E-26 T 18-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TWT_256 2e6901894ef00d83e1efd410a8fcb40e 156 Gene3D G3DSA:3.40.30.10 4 156 9.0E-37 T 18-10-2018 TWT_256 2e6901894ef00d83e1efd410a8fcb40e 156 SUPERFAMILY SSF52833 11 155 1.74E-35 T 18-10-2018 IPR036249 Thioredoxin-like superfamily TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 1.0E-5 T 18-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 18-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 358 2.1E-82 T 18-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 18-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 Pfam PF00953 Glycosyl transferase family 4 82 289 7.2E-32 T 18-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TWT_224 9b136d72255ffd75f29feb2ccece4faa 369 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 363 22.233 T 18-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_552 4b91de53e56be2561c40ccdd1152eeff 103 SUPERFAMILY SSF54189 14 98 4.32E-30 T 18-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_552 4b91de53e56be2561c40ccdd1152eeff 103 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 16 103 19.214 T 18-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TWT_552 4b91de53e56be2561c40ccdd1152eeff 103 Gene3D G3DSA:3.30.70.330 14 103 9.2E-31 T 18-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TWT_552 4b91de53e56be2561c40ccdd1152eeff 103 ProSitePatterns PS00050 Ribosomal protein L23 signature. 88 103 - T 18-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_552 4b91de53e56be2561c40ccdd1152eeff 103 Pfam PF00276 Ribosomal protein L23 17 97 3.0E-30 T 18-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TWT_516 30af878b1ad6c34920cc88469f4f230f 424 Pfam PF10103 Zincin-like metallopeptidase 37 375 1.2E-78 T 18-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TWT_516 30af878b1ad6c34920cc88469f4f230f 424 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 37 379 2.6E-70 T 18-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TWT_516 30af878b1ad6c34920cc88469f4f230f 424 SUPERFAMILY SSF55486 36 379 8.06E-76 T 18-10-2018 TWT_382 b70bf4ffde551dedfdef3bccc36abf55 278 Gene3D G3DSA:3.60.15.10 29 274 9.2E-44 T 18-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TWT_382 b70bf4ffde551dedfdef3bccc36abf55 278 SUPERFAMILY SSF56281 29 275 9.07E-29 T 18-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TWT_406 09de8a6d89f380178991465936efbc68 184 Gene3D G3DSA:3.30.420.10 4 183 3.7E-59 T 18-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TWT_406 09de8a6d89f380178991465936efbc68 184 SMART SM00479 9 181 3.4E-21 T 18-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TWT_406 09de8a6d89f380178991465936efbc68 184 SUPERFAMILY SSF53098 7 179 1.04E-38 T 18-10-2018 IPR012337 Ribonuclease H-like superfamily TWT_406 09de8a6d89f380178991465936efbc68 184 Hamap MF_00045 Oligoribonuclease [orn]. 5 182 36.031 T 18-10-2018 IPR022894 Oligoribonuclease GO:0000175 TWT_406 09de8a6d89f380178991465936efbc68 184 Pfam PF00929 Exonuclease 11 171 5.0E-23 T 18-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Hamap MF_00974 DNA primase [dnaG]. 3 591 24.837 T 18-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF10410 DnaB-helicase binding domain of primase 361 415 1.3E-11 T 18-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 405 7.4E-116 T 18-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.90.980.10 107 231 3.2E-32 T 18-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 SMART SM00493 250 324 2.2E-11 T 18-10-2018 IPR006171 TOPRIM domain TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF13662 Toprim domain 251 317 3.7E-13 T 18-10-2018 IPR006171 TOPRIM domain TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 SUPERFAMILY SSF56731 111 415 1.88E-87 T 18-10-2018 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF01807 CHC2 zinc finger 5 98 7.6E-33 T 18-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 SUPERFAMILY SSF57783 1 96 7.82E-31 T 18-10-2018 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 SMART SM00400 36 89 1.2E-29 T 18-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.40.1360.10 232 358 1.7E-33 T 18-10-2018 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 PIRSF PIRSF002811 1 600 1.9E-145 T 18-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 121 242 1.9E-34 T 18-10-2018 IPR013264 DNA primase, catalytic core, N-terminal TWT_288 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.90.580.10 1 100 1.3E-35 T 18-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 61 87 - T 18-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 Pfam PF00238 Ribosomal protein L14p/L23e 2 123 5.8E-51 T 18-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 25.227 T 18-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 SMART SM01374 1 123 2.3E-79 T 18-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 SUPERFAMILY SSF50193 2 123 2.09E-46 T 18-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 Gene3D G3DSA:2.40.150.20 1 123 2.5E-49 T 18-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TWT_544 3d7bd6839c8616229a83e87fc42cefb4 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 2.4E-53 T 18-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TWT_502 df93932b242febd9b5810104af9ff5b8 450 Gene3D G3DSA:3.30.390.30 329 448 6.5E-33 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_502 df93932b242febd9b5810104af9ff5b8 450 SUPERFAMILY SSF55424 329 448 1.29E-29 T 18-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TWT_502 df93932b242febd9b5810104af9ff5b8 450 Gene3D G3DSA:3.50.50.60 141 256 8.9E-99 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 4.5E-41 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 4.5E-41 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.5E-41 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 4.5E-41 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 4.5E-41 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PIRSF PIRSF000350 1 444 1.1E-71 T 18-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TWT_502 df93932b242febd9b5810104af9ff5b8 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 438 2.7E-25 T 18-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TWT_502 df93932b242febd9b5810104af9ff5b8 450 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 448 7.6E-131 T 18-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TWT_502 df93932b242febd9b5810104af9ff5b8 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 18-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TWT_502 df93932b242febd9b5810104af9ff5b8 450 Gene3D G3DSA:3.50.50.60 3 315 8.9E-99 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_502 df93932b242febd9b5810104af9ff5b8 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 310 7.8E-64 T 18-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TWT_502 df93932b242febd9b5810104af9ff5b8 450 SUPERFAMILY SSF51905 1 354 8.6E-53 T 18-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 433 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 406 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 347 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.4E-67 T 18-10-2018 TWT_502 df93932b242febd9b5810104af9ff5b8 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 1.4E-67 T 18-10-2018 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 ProSitePatterns PS00802 Transketolase signature 2. 432 448 - T 18-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.920 507 626 9.5E-20 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.970 324 493 2.3E-60 T 18-10-2018 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 621 1.4E-161 T 18-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 623 36.539 T 18-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52922 503 623 1.83E-21 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52518 27 373 2.62E-60 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF02779 Transketolase, pyrimidine binding domain 327 487 3.5E-35 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_484 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52518 302 487 4.42E-53 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_484 6bd7534ab796f271f9e1faba00da7241 629 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 18-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 SMART SM00861 326 490 1.2E-53 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 286 3.2E-98 T 18-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_484 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF02780 Transketolase, C-terminal domain 509 614 4.1E-14 T 18-10-2018 IPR033248 Transketolase, C-terminal domain TWT_287 6a22a02d5a786d81922acf999b3cee93 479 Gene3D G3DSA:1.10.3210.10 8 459 7.7E-78 T 18-10-2018 TWT_287 6a22a02d5a786d81922acf999b3cee93 479 SUPERFAMILY SSF109604 29 259 3.37E-49 T 18-10-2018 TWT_287 6a22a02d5a786d81922acf999b3cee93 479 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 41 459 2.1E-73 T 18-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TWT_287 6a22a02d5a786d81922acf999b3cee93 479 SMART SM00471 75 257 1.6E-9 T 18-10-2018 IPR003607 HD/PDEase domain TWT_287 6a22a02d5a786d81922acf999b3cee93 479 Pfam PF13286 Phosphohydrolase-associated domain 365 457 1.9E-13 T 18-10-2018 IPR026875 Phosphohydrolase-associated domain TWT_287 6a22a02d5a786d81922acf999b3cee93 479 Pfam PF01966 HD domain 79 246 1.2E-14 T 18-10-2018 IPR006674 HD domain TWT_235 43b052bd4d596d3c45116e314ff0887c 225 Pfam PF00376 MerR family regulatory protein 13 54 1.6E-11 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_235 43b052bd4d596d3c45116e314ff0887c 225 Gene3D G3DSA:1.10.1660.10 2 87 2.4E-15 T 18-10-2018 TWT_235 43b052bd4d596d3c45116e314ff0887c 225 SMART SM00422 12 86 1.4E-13 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_235 43b052bd4d596d3c45116e314ff0887c 225 SUPERFAMILY SSF46955 13 89 1.14E-10 T 18-10-2018 IPR009061 Putative DNA-binding domain superfamily TWT_567 cdcda526a4ec881b4629dc6de0761047 486 PIRSF PIRSF000505 46 486 6.6E-106 T 18-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 62 478 7.1E-97 T 18-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 SUPERFAMILY SSF55205 63 482 7.2E-99 T 18-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 56 486 26.667 T 18-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 Gene3D G3DSA:3.65.10.10 68 304 1.3E-123 T 18-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 ProSitePatterns PS00885 EPSP synthase signature 2. 399 417 - T 18-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 Gene3D G3DSA:3.65.10.10 62 476 1.3E-123 T 18-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TWT_567 cdcda526a4ec881b4629dc6de0761047 486 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 62 482 1.1E-104 T 18-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 Pfam PF00444 Ribosomal protein L36 4 39 2.2E-16 T 18-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 SUPERFAMILY SSF57840 4 39 3.4E-15 T 18-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 ProSitePatterns PS00828 Ribosomal protein L36 signature. 13 38 - T 18-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 11 39 2.0E-9 T 18-10-2018 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 4 39 1.1E-18 T 18-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_531 8cef982ba859902d06fd9f107ce3e94b 39 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 3 39 16.226 T 18-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 SMART SM01005 254 385 3.6E-6 T 18-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 Gene3D G3DSA:3.20.20.10 18 242 3.3E-51 T 18-10-2018 IPR029066 PLP-binding barrel TWT_496 fca635ac8e49829c7a151888cbb55aec 386 SUPERFAMILY SSF51419 16 260 2.43E-35 T 18-10-2018 IPR029066 PLP-binding barrel TWT_496 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 34 50 3.7E-13 T 18-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 220 247 3.7E-13 T 18-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 141 153 3.7E-13 T 18-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 Gene3D G3DSA:2.40.37.10 16 380 3.3E-51 T 18-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 Pfam PF01168 Alanine racemase, N-terminal domain 16 246 3.6E-39 T 18-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_496 fca635ac8e49829c7a151888cbb55aec 386 Hamap MF_01201 Alanine racemase. 9 385 14.363 T 18-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 SMART SM00465 12 93 1.1E-17 T 18-10-2018 IPR000305 GIY-YIG endonuclease TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 SUPERFAMILY SSF46600 188 237 3.01E-11 T 18-10-2018 IPR036876 UVR domain superfamily TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Gene3D G3DSA:3.30.420.340 379 542 9.8E-51 T 18-10-2018 IPR038476 UvrC homology region 2 superfamily TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 385 535 1.2E-45 T 18-10-2018 IPR001162 UvrC family homology region TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 SUPERFAMILY SSF47781 495 600 2.41E-16 T 18-10-2018 IPR010994 RuvA domain 2-like TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Gene3D G3DSA:3.40.1440.10 5 97 7.3E-26 T 18-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 600 24.521 T 18-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Pfam PF02151 UvrB/uvrC motif 202 234 9.2E-8 T 18-10-2018 IPR001943 UVR domain GO:0005515 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 582 6.5E-140 T 18-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Pfam PF01541 GIY-YIG catalytic domain 13 85 2.2E-10 T 18-10-2018 IPR000305 GIY-YIG endonuclease TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Gene3D G3DSA:1.10.150.20 543 601 5.8E-14 T 18-10-2018 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 Pfam PF14520 Helix-hairpin-helix domain 550 601 1.1E-10 T 18-10-2018 TWT_297 7b8799caa2505f03eae3f00e6c44d582 607 SUPERFAMILY SSF82771 12 95 3.27E-19 T 18-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 SUPERFAMILY SSF51161 406 585 3.06E-42 T 18-10-2018 IPR011004 Trimeric LpxA-like superfamily TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 14 601 31.307 T 18-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Gene3D G3DSA:3.90.550.10 307 401 2.8E-7 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 SUPERFAMILY SSF53448 15 259 3.07E-28 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 419 449 2.4E-4 T 18-10-2018 IPR001451 Hexapeptide repeat TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 467 500 3.8E-7 T 18-10-2018 IPR001451 Hexapeptide repeat TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 546 577 2.6E-4 T 18-10-2018 IPR001451 Hexapeptide repeat TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Gene3D G3DSA:2.160.10.10 402 587 1.6E-49 T 18-10-2018 TWT_188 662f81a79d883ba0541e4d8e1b5542fd 605 Pfam PF12804 MobA-like NTP transferase domain 18 205 2.8E-13 T 18-10-2018 IPR025877 MobA-like NTP transferase TWT_162 cab15f12598ea8612f986aef7b6062de 822 SUPERFAMILY SSF51726 5 391 8.11E-69 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_162 cab15f12598ea8612f986aef7b6062de 822 Gene3D G3DSA:3.20.20.210 390 700 1.2E-151 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_162 cab15f12598ea8612f986aef7b6062de 822 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 455 696 2.2E-43 T 18-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TWT_162 cab15f12598ea8612f986aef7b6062de 822 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 317 9.6E-94 T 18-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TWT_162 cab15f12598ea8612f986aef7b6062de 822 Gene3D G3DSA:3.20.20.210 6 506 1.2E-151 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_162 cab15f12598ea8612f986aef7b6062de 822 SUPERFAMILY SSF51726 418 699 5.62E-38 T 18-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TWT_336 85f4e406c13698bc6bbf8ff202b7984b 384 SUPERFAMILY SSF101960 22 375 2.62E-72 T 18-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TWT_336 85f4e406c13698bc6bbf8ff202b7984b 384 Pfam PF01458 Uncharacterized protein family (UPF0051) 130 350 3.4E-61 T 18-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 61 291 4.4E-46 T 18-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 SUPERFAMILY SSF82866 84 304 1.83E-35 T 18-10-2018 TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 Gene3D G3DSA:1.20.1640.10 130 317 6.3E-12 T 18-10-2018 TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 Pfam PF02355 Protein export membrane protein 114 301 1.2E-53 T 18-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 47 294 3.3E-60 T 18-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 24.12 T 18-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 PRINTS PR01755 Bacterial translocase SecF protein signature 204 222 6.3E-17 T 18-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 6.3E-17 T 18-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TWT_272 d2baa7d5c52853e9bfc62c8349b302e4 322 PRINTS PR01755 Bacterial translocase SecF protein signature 46 61 6.3E-17 T 18-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Gene3D G3DSA:1.10.10.160 112 202 2.0E-85 T 18-10-2018 IPR013986 DExx box DNA helicase domain superfamily TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Gene3D G3DSA:3.40.50.300 11 289 2.0E-85 T 18-10-2018 TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 287 3.0E-69 T 18-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Gene3D G3DSA:3.40.50.300 296 641 1.3E-113 T 18-10-2018 TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Pfam PF13361 UvrD-like helicase C-terminal domain 293 626 1.7E-71 T 18-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 SUPERFAMILY SSF52540 4 650 2.31E-157 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_080 a7f774d2a4b8af8f8e2058d369a49987 743 Gene3D G3DSA:1.10.486.10 398 558 1.3E-113 T 18-10-2018 TWT_682 800ce661bda4d1b515d9f1d050c05355 327 Pfam PF00268 Ribonucleotide reductase, small chain 14 295 2.3E-69 T 18-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_682 800ce661bda4d1b515d9f1d050c05355 327 PIRSF PIRSF000355 1 326 3.2E-108 T 18-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_682 800ce661bda4d1b515d9f1d050c05355 327 Gene3D G3DSA:1.10.620.20 7 321 1.5E-89 T 18-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TWT_682 800ce661bda4d1b515d9f1d050c05355 327 SUPERFAMILY SSF47240 11 299 1.58E-81 T 18-10-2018 IPR009078 Ferritin-like superfamily TWT_733 5a7610188d987b73216dbb642d2eb92e 391 SUPERFAMILY SSF53800 29 382 1.96E-72 T 18-10-2018 TWT_733 5a7610188d987b73216dbb642d2eb92e 391 Pfam PF00762 Ferrochelatase 31 348 1.9E-85 T 18-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TWT_733 5a7610188d987b73216dbb642d2eb92e 391 Gene3D G3DSA:3.40.50.1400 33 345 5.5E-103 T 18-10-2018 TWT_733 5a7610188d987b73216dbb642d2eb92e 391 Gene3D G3DSA:3.40.50.1400 174 330 5.5E-103 T 18-10-2018 TWT_733 5a7610188d987b73216dbb642d2eb92e 391 Hamap MF_00323 Ferrochelatase [hemH]. 29 349 26.854 T 18-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TWT_733 5a7610188d987b73216dbb642d2eb92e 391 ProSitePatterns PS00534 Ferrochelatase signature. 206 226 - T 18-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TWT_353 6de7bfb590c5eed387c524db1b71bb1e 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 293 5.4E-22 T 18-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TWT_353 6de7bfb590c5eed387c524db1b71bb1e 297 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 18 289 1.2E-77 T 18-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TWT_353 6de7bfb590c5eed387c524db1b71bb1e 297 Gene3D G3DSA:1.10.3720.10 7 284 1.6E-29 T 18-10-2018 IPR035906 MetI-like superfamily TWT_353 6de7bfb590c5eed387c524db1b71bb1e 297 SUPERFAMILY SSF161098 28 284 1.44E-37 T 18-10-2018 IPR035906 MetI-like superfamily TWT_309 d60ad1d64228c7b3a88887e0dfab6f34 272 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 257 1.2E-46 T 18-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TWT_309 d60ad1d64228c7b3a88887e0dfab6f34 272 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 11 263 3.4E-35 T 18-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TWT_309 d60ad1d64228c7b3a88887e0dfab6f34 272 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 264 14.51 T 18-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 182 221 1.0E-5 T 18-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 Gene3D G3DSA:3.40.50.1000 86 181 4.4E-73 T 18-10-2018 IPR023214 HAD superfamily TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 108 8.1E-23 T 18-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 Gene3D G3DSA:3.40.50.1000 9 244 4.4E-73 T 18-10-2018 IPR023214 HAD superfamily TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 230 9.3E-42 T 18-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 SUPERFAMILY SSF56784 6 252 6.33E-65 T 18-10-2018 IPR036412 HAD-like superfamily TWT_742 ba8dbd7cf4cb50a076b4bc3d4151ea28 261 Pfam PF13242 HAD-hyrolase-like 181 252 3.1E-23 T 18-10-2018 TWT_786 83e7b04e7204ac134d273b00eced9ad6 385 Gene3D G3DSA:1.20.1530.10 1 373 2.4E-99 T 18-10-2018 IPR023171 Na/H antiporter domain superfamily TWT_786 83e7b04e7204ac134d273b00eced9ad6 385 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 1 372 17.442 T 18-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TWT_786 83e7b04e7204ac134d273b00eced9ad6 385 Pfam PF06965 Na+/H+ antiporter 1 3 364 2.8E-94 T 18-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TWT_312 95ff8c4edc645b1af34ead9b8a0d5265 391 Pfam PF00534 Glycosyl transferases group 1 208 352 4.6E-34 T 18-10-2018 IPR001296 Glycosyl transferase, family 1 TWT_312 95ff8c4edc645b1af34ead9b8a0d5265 391 Pfam PF13439 Glycosyltransferase Family 4 20 202 1.5E-23 T 18-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TWT_312 95ff8c4edc645b1af34ead9b8a0d5265 391 SUPERFAMILY SSF53756 9 384 1.72E-78 T 18-10-2018 TWT_312 95ff8c4edc645b1af34ead9b8a0d5265 391 Gene3D G3DSA:3.40.50.2000 4 211 4.0E-31 T 18-10-2018 TWT_312 95ff8c4edc645b1af34ead9b8a0d5265 391 Gene3D G3DSA:3.40.50.2000 212 370 5.5E-41 T 18-10-2018 TWT_393 737db00bc12b8dfefe810c4a5920c618 207 Pfam PF11452 Protein of unknown function (DUF3000) 33 203 9.2E-54 T 18-10-2018 IPR021555 Protein of unknown function DUF3000 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 23 175 8.4E-41 T 18-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 SUPERFAMILY SSF48179 195 335 3.06E-39 T 18-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 Gene3D G3DSA:1.10.1040.10 200 336 3.5E-35 T 18-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 Gene3D G3DSA:3.40.50.720 10 199 1.4E-51 T 18-10-2018 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 204 225 - T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PIRSF PIRSF000114 16 339 2.7E-99 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 196 331 1.3E-38 T 18-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 254 271 9.0E-34 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 26 43 9.0E-34 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 149 169 9.0E-34 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 214 238 9.0E-34 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 189 213 9.0E-34 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 22 334 29.924 T 18-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TWT_506 3aca96a2c45f2787f88e75daa1f155b8 339 SUPERFAMILY SSF51735 22 196 2.87E-41 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_257 893d6f81aea704c1d8125feed6983fdd 284 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 13 276 8.2E-41 T 18-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TWT_257 893d6f81aea704c1d8125feed6983fdd 284 Gene3D G3DSA:3.40.1390.30 107 245 8.9E-58 T 18-10-2018 TWT_257 893d6f81aea704c1d8125feed6983fdd 284 SUPERFAMILY SSF102705 13 282 1.83E-70 T 18-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TWT_257 893d6f81aea704c1d8125feed6983fdd 284 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 13 267 4.3E-71 T 18-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TWT_257 893d6f81aea704c1d8125feed6983fdd 284 Gene3D G3DSA:3.40.1390.30 15 254 8.9E-58 T 18-10-2018 TWT_439 40218ce7e7234862573ff2f1b7965137 489 Gene3D G3DSA:3.40.50.720 39 372 7.8E-117 T 18-10-2018 TWT_439 40218ce7e7234862573ff2f1b7965137 489 Pfam PF00742 Homoserine dehydrogenase 168 348 1.2E-61 T 18-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TWT_439 40218ce7e7234862573ff2f1b7965137 489 SUPERFAMILY SSF55347 168 335 1.05E-48 T 18-10-2018 TWT_439 40218ce7e7234862573ff2f1b7965137 489 SUPERFAMILY SSF51735 36 189 1.04E-26 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_439 40218ce7e7234862573ff2f1b7965137 489 Gene3D G3DSA:3.30.70.260 381 463 7.8E-117 T 18-10-2018 TWT_439 40218ce7e7234862573ff2f1b7965137 489 Gene3D G3DSA:3.30.360.10 167 380 7.8E-117 T 18-10-2018 TWT_439 40218ce7e7234862573ff2f1b7965137 489 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 44 160 1.5E-15 T 18-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TWT_439 40218ce7e7234862573ff2f1b7965137 489 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 214 236 - T 18-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 47 185 1.7E-32 T 18-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 318 426 9.4E-16 T 18-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 38 194 1.7E-41 T 18-10-2018 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 35 232 7.95E-38 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 207 313 5.0E-26 T 18-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 301 434 1.12E-29 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 315 431 1.6E-26 T 18-10-2018 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 141 155 9.4E-7 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 245 9.4E-7 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 293 308 9.4E-7 T 18-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 223 314 2.03E-17 T 18-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF55957 435 533 2.62E-7 T 18-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 228 313 6.3E-17 T 18-10-2018 TWT_017 15545a5e8ccf666a50232f379dd0d836 550 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 18-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 SUPERFAMILY SSF46589 15 100 5.75E-11 T 18-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 Gene3D G3DSA:3.30.930.10 11 335 1.0E-92 T 18-10-2018 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 Pfam PF01409 tRNA synthetases class II core domain (F) 95 333 3.5E-86 T 18-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 89 1.0E-8 T 18-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 48 333 2.8E-72 T 18-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 SUPERFAMILY SSF55681 95 334 1.14E-66 T 18-10-2018 TWT_167 6917b8d7a5252366e056c977a4bd7e65 336 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 333 36.991 T 18-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 SUPERFAMILY SSF55486 33 688 9.52E-192 T 18-10-2018 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 Pfam PF01431 Peptidase family M13 483 684 1.0E-68 T 18-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 Gene3D G3DSA:3.40.390.10 35 688 8.9E-213 T 18-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 Gene3D G3DSA:1.10.1380.10 63 470 8.9E-213 T 18-10-2018 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 Pfam PF05649 Peptidase family M13 37 432 6.5E-92 T 18-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 587 598 1.0E-21 T 18-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 475 487 1.0E-21 T 18-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 493 505 1.0E-21 T 18-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TWT_769 69c1ac409847b3f5eb941c4cb13ccd7e 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 514 530 1.0E-21 T 18-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Pfam PF00204 DNA gyrase B 222 413 2.0E-53 T 18-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 527 544 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 36 51 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 594 610 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 71 84 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 288 301 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 547 559 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 443 457 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR00418 DNA topoisomerase II family signature 509 525 2.7E-59 T 18-10-2018 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 445 453 - T 18-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 SUPERFAMILY SSF54211 270 413 3.03E-36 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 SMART SM00433 36 655 5.6E-236 T 18-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Gene3D G3DSA:3.40.50.670 422 662 2.7E-86 T 18-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 SUPERFAMILY SSF55874 7 211 2.23E-54 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Pfam PF01751 Toprim domain 442 543 2.0E-14 T 18-10-2018 IPR006171 TOPRIM domain TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 175 7.3E-16 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 182 197 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 7 17 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 197 210 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 493 502 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 397 417 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 631 647 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 615 627 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 221 243 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 PRINTS PR01159 DNA gyrase subunit B signature 333 349 2.6E-31 T 18-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 594 650 7.3E-25 T 18-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Gene3D G3DSA:3.30.565.10 3 220 4.5E-75 T 18-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 SUPERFAMILY SSF56719 417 654 2.88E-74 T 18-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 SMART SM00387 32 177 7.3E-20 T 18-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TWT_494 bb96a59956b40b1c0918ff3b811fa96e 662 Gene3D G3DSA:3.30.230.10 221 421 4.7E-49 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_379 267a36ac45abfff5e0ef252bef164ef6 453 Pfam PF03993 Domain of Unknown Function (DUF349) 227 295 1.5E-9 T 18-10-2018 IPR007139 Protein of unknown function DUF349 TWT_379 267a36ac45abfff5e0ef252bef164ef6 453 Pfam PF03993 Domain of Unknown Function (DUF349) 300 372 7.0E-9 T 18-10-2018 IPR007139 Protein of unknown function DUF349 TWT_618 db3e62eb0ecb504524c99594d670fc32 129 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 44 119 16.594 T 18-10-2018 IPR003482 Transcription factor WhiB TWT_618 db3e62eb0ecb504524c99594d670fc32 129 Pfam PF02467 Transcription factor WhiB 46 114 6.3E-24 T 18-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 18-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 SUPERFAMILY SSF51735 1 321 2.49E-97 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 Gene3D G3DSA:3.90.25.10 194 314 6.2E-126 T 18-10-2018 TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 321 1.5E-136 T 18-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 Gene3D G3DSA:3.40.50.720 4 306 6.2E-126 T 18-10-2018 TWT_030 17069d3884c74e0c4f28f0ccaec7d225 327 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 307 1.0E-82 T 18-10-2018 IPR016040 NAD(P)-binding domain TWT_340 18e371b99045f6435776f054cdfb2d49 698 SUPERFAMILY SSF52518 362 556 1.2E-66 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_340 18e371b99045f6435776f054cdfb2d49 698 SUPERFAMILY SSF52518 20 343 4.17E-94 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_340 18e371b99045f6435776f054cdfb2d49 698 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 18-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_340 18e371b99045f6435776f054cdfb2d49 698 SUPERFAMILY SSF52922 565 695 5.14E-38 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_340 18e371b99045f6435776f054cdfb2d49 698 Pfam PF02779 Transketolase, pyrimidine binding domain 373 553 4.8E-44 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_340 18e371b99045f6435776f054cdfb2d49 698 Gene3D G3DSA:3.40.50.970 359 560 1.1E-74 T 18-10-2018 TWT_340 18e371b99045f6435776f054cdfb2d49 698 Gene3D G3DSA:3.40.50.970 8 355 4.0E-103 T 18-10-2018 TWT_340 18e371b99045f6435776f054cdfb2d49 698 Gene3D G3DSA:3.40.50.920 568 690 4.5E-39 T 18-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TWT_340 18e371b99045f6435776f054cdfb2d49 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 24 359 8.3E-122 T 18-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TWT_340 18e371b99045f6435776f054cdfb2d49 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 26 693 2.5E-226 T 18-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TWT_340 18e371b99045f6435776f054cdfb2d49 698 SMART SM00861 374 554 1.6E-63 T 18-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TWT_340 18e371b99045f6435776f054cdfb2d49 698 Pfam PF02780 Transketolase, C-terminal domain 580 685 9.2E-10 T 18-10-2018 IPR033248 Transketolase, C-terminal domain TWT_645 deda585d0d58d0a5c0fb2ccaeac6989d 439 PIRSF PIRSF002808 1 438 1.0E-36 T 18-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 TWT_645 deda585d0d58d0a5c0fb2ccaeac6989d 439 Gene3D G3DSA:1.20.1250.20 226 427 1.7E-31 T 18-10-2018 TWT_645 deda585d0d58d0a5c0fb2ccaeac6989d 439 SUPERFAMILY SSF103473 6 422 1.27E-74 T 18-10-2018 IPR036259 MFS transporter superfamily TWT_645 deda585d0d58d0a5c0fb2ccaeac6989d 439 Pfam PF07690 Major Facilitator Superfamily 16 385 8.0E-53 T 18-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TWT_645 deda585d0d58d0a5c0fb2ccaeac6989d 439 Gene3D G3DSA:1.20.1250.20 2 200 4.6E-36 T 18-10-2018 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 116 124 - T 18-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 Pfam PF00334 Nucleoside diphosphate kinase 2 136 4.7E-47 T 18-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 SUPERFAMILY SSF54919 2 136 9.04E-49 T 18-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 Gene3D G3DSA:3.30.70.141 1 136 4.1E-49 T 18-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 SMART SM00562 1 136 8.2E-54 T 18-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 7.9E-31 T 18-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 7.9E-31 T 18-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 7.9E-31 T 18-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_475 59d18c06fb603acca6ed4e552c27cc5d 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 116 135 7.9E-31 T 18-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TWT_049 2fc9b8824ba5eb41caa76c7c44e67f78 260 SUPERFAMILY SSF52540 6 253 1.31E-62 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_049 2fc9b8824ba5eb41caa76c7c44e67f78 260 Gene3D G3DSA:3.40.50.300 1 255 2.0E-76 T 18-10-2018 TWT_049 2fc9b8824ba5eb41caa76c7c44e67f78 260 PIRSF PIRSF009320 6 53 1.7E-15 T 18-10-2018 TWT_049 2fc9b8824ba5eb41caa76c7c44e67f78 260 PIRSF PIRSF009320 90 258 3.7E-6 T 18-10-2018 TWT_049 2fc9b8824ba5eb41caa76c7c44e67f78 260 Pfam PF13614 AAA domain 7 179 4.4E-58 T 18-10-2018 IPR025669 AAA domain TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 SUPERFAMILY SSF55920 35 307 4.06E-83 T 18-10-2018 IPR036005 Creatinase/aminopeptidase-like TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 Hamap MF_01974 Methionine aminopeptidase [map]. 61 308 39.42 T 18-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 63 307 1.6E-89 T 18-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 Gene3D G3DSA:3.90.230.10 26 308 3.5E-108 T 18-10-2018 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 PRINTS PR00599 Methionine aminopeptidase-1 signature 250 262 1.2E-21 T 18-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 139 1.2E-21 T 18-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 PRINTS PR00599 Methionine aminopeptidase-1 signature 148 164 1.2E-21 T 18-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 230 1.2E-21 T 18-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 224 242 - T 18-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TWT_259 2cc84fb0c8a25145dc10db12cde110ce 308 Pfam PF00557 Metallopeptidase family M24 71 299 2.5E-50 T 18-10-2018 IPR000994 Peptidase M24 TWT_217 a989b48a49794c223dd6407643dc857e 379 SUPERFAMILY SSF48576 20 375 2.16E-60 T 18-10-2018 IPR008949 Isoprenoid synthase domain superfamily TWT_217 a989b48a49794c223dd6407643dc857e 379 Gene3D G3DSA:1.10.600.10 23 379 1.9E-76 T 18-10-2018 IPR008949 Isoprenoid synthase domain superfamily TWT_217 a989b48a49794c223dd6407643dc857e 379 Pfam PF00348 Polyprenyl synthetase 56 331 2.0E-43 T 18-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TWT_217 a989b48a49794c223dd6407643dc857e 379 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 104 118 - T 18-10-2018 IPR033749 Polyprenyl synthetase, conserved site TWT_517 c1b9cad959b353055d7d5e294754fef7 585 SUPERFAMILY SSF52540 6 576 7.79E-96 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:1.10.486.10 475 498 4.9E-23 T 18-10-2018 TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 9 270 6.0E-62 T 18-10-2018 TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Pfam PF13245 AAA domain 15 254 3.1E-28 T 18-10-2018 TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:1.10.10.160 107 187 6.0E-62 T 18-10-2018 IPR013986 DExx box DNA helicase domain superfamily TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Pfam PF13361 UvrD-like helicase C-terminal domain 510 567 7.9E-19 T 18-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TWT_517 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 499 576 4.9E-23 T 18-10-2018 TWT_091 e3e34ab73133dbe04476d0e007845b41 545 SUPERFAMILY SSF52540 23 343 1.45E-19 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_091 e3e34ab73133dbe04476d0e007845b41 545 Gene3D G3DSA:3.40.50.300 23 343 3.2E-23 T 18-10-2018 TWT_091 e3e34ab73133dbe04476d0e007845b41 545 Pfam PF13175 AAA ATPase domain 23 116 1.6E-12 T 18-10-2018 TWT_091 e3e34ab73133dbe04476d0e007845b41 545 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 265 323 6.4E-12 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_362 102239e5a2858d5988e5535682919b8a 98 SMART SM01409 27 92 3.0E-12 T 18-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TWT_362 102239e5a2858d5988e5535682919b8a 98 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 20 93 14.961 T 18-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_362 102239e5a2858d5988e5535682919b8a 98 SUPERFAMILY SSF63562 20 94 5.41E-20 T 18-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TWT_362 102239e5a2858d5988e5535682919b8a 98 Pfam PF01192 RNA polymerase Rpb6 28 91 3.7E-12 T 18-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TWT_362 102239e5a2858d5988e5535682919b8a 98 Gene3D G3DSA:3.90.940.10 20 98 1.5E-15 T 18-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TWT_362 102239e5a2858d5988e5535682919b8a 98 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 20 90 1.9E-16 T 18-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TWT_381 2c48372856f049fc45155f024004eaf3 309 Gene3D G3DSA:1.20.272.10 194 307 7.2E-14 T 18-10-2018 TWT_381 2c48372856f049fc45155f024004eaf3 309 SUPERFAMILY SSF48019 195 304 7.99E-17 T 18-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TWT_381 2c48372856f049fc45155f024004eaf3 309 Gene3D G3DSA:3.40.50.300 1 117 8.1E-10 T 18-10-2018 TWT_059 a20cace07938184ffcb7b1dc4f0c0891 395 Gene3D G3DSA:1.10.3470.10 69 392 2.0E-80 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_059 a20cace07938184ffcb7b1dc4f0c0891 395 SUPERFAMILY SSF81345 67 388 2.35E-67 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_059 a20cace07938184ffcb7b1dc4f0c0891 395 Pfam PF01032 FecCD transport family 82 388 1.6E-81 T 18-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TWT_485 23af7a18d3fb30297243ac7398344a00 218 Pfam PF11361 Protein of unknown function (DUF3159) 31 215 4.7E-58 T 18-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TWT_485 23af7a18d3fb30297243ac7398344a00 218 PIRSF PIRSF010219 4 218 2.9E-80 T 18-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TWT_107 165032e7ab89861135ebc00196b6c1f9 186 SUPERFAMILY SSF50249 4 186 1.23E-38 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_107 165032e7ab89861135ebc00196b6c1f9 186 Gene3D G3DSA:2.40.50.140 1 117 6.5E-37 T 18-10-2018 TWT_107 165032e7ab89861135ebc00196b6c1f9 186 Hamap MF_00984 Single-stranded DNA-binding protein. 2 111 28.783 T 18-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TWT_107 165032e7ab89861135ebc00196b6c1f9 186 Pfam PF00436 Single-strand binding protein family 4 104 2.5E-23 T 18-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TWT_107 165032e7ab89861135ebc00196b6c1f9 186 PIRSF PIRSF002070 2 158 4.1E-25 T 18-10-2018 TWT_107 165032e7ab89861135ebc00196b6c1f9 186 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 186 1.5E-28 T 18-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 266 285 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 159 182 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 58 76 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 285 304 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 85 100 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 PRINTS PR00714 Phosphomannose isomerase type I signature 304 323 8.4E-26 T 18-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 Gene3D G3DSA:2.60.120.10 331 360 1.6E-80 T 18-10-2018 IPR014710 RmlC-like jelly roll fold TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 SUPERFAMILY SSF51182 53 362 1.19E-61 T 18-10-2018 IPR011051 RmlC-like cupin domain superfamily TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 Gene3D G3DSA:1.10.441.10 184 330 1.6E-80 T 18-10-2018 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 Pfam PF01238 Phosphomannose isomerase type I 244 335 3.6E-15 T 18-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 Pfam PF01238 Phosphomannose isomerase type I 56 195 1.2E-24 T 18-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 55 363 3.0E-49 T 18-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TWT_122 1286f4a38261ed94393d93c7878b7bf0 504 Gene3D G3DSA:2.60.120.10 60 305 1.6E-80 T 18-10-2018 IPR014710 RmlC-like jelly roll fold TWT_057 7159436cbf69c4d6381b35cdde7d77c3 331 Pfam PF01497 Periplasmic binding protein 107 294 9.6E-16 T 18-10-2018 IPR002491 ABC transporter periplasmic binding domain TWT_057 7159436cbf69c4d6381b35cdde7d77c3 331 Gene3D G3DSA:3.40.50.1980 32 171 4.9E-30 T 18-10-2018 TWT_057 7159436cbf69c4d6381b35cdde7d77c3 331 Gene3D G3DSA:3.40.50.1980 175 329 2.6E-21 T 18-10-2018 TWT_057 7159436cbf69c4d6381b35cdde7d77c3 331 SUPERFAMILY SSF53807 53 321 2.59E-37 T 18-10-2018 TWT_298 413473b085e5287901acc742c862bce1 319 SUPERFAMILY SSF55608 117 221 1.0E-6 T 18-10-2018 IPR027434 Homing endonuclease TWT_298 413473b085e5287901acc742c862bce1 319 Gene3D G3DSA:3.10.28.10 10 217 2.5E-15 T 18-10-2018 IPR027434 Homing endonuclease TWT_298 413473b085e5287901acc742c862bce1 319 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 7 308 23.547 T 18-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 TWT_298 413473b085e5287901acc742c862bce1 319 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 15 306 5.1E-49 T 18-10-2018 IPR033981 Sporulation regulator WhiA-like TWT_298 413473b085e5287901acc742c862bce1 319 Gene3D G3DSA:1.10.10.10 219 309 8.0E-12 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_298 413473b085e5287901acc742c862bce1 319 Pfam PF14527 WhiA LAGLIDADG-like domain 129 218 1.1E-22 T 18-10-2018 IPR039518 WhiA, LAGLIDADG-like domain TWT_298 413473b085e5287901acc742c862bce1 319 Pfam PF02650 WhiA C-terminal HTH domain 225 304 1.2E-16 T 18-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal TWT_298 413473b085e5287901acc742c862bce1 319 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 25 105 2.3E-12 T 18-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain TWT_724 879c6d32cca170e85be4fe319378469a 337 SUPERFAMILY SSF56042 170 330 1.45E-43 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_724 879c6d32cca170e85be4fe319378469a 337 SUPERFAMILY SSF55326 4 166 1.67E-41 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_724 879c6d32cca170e85be4fe319378469a 337 Gene3D G3DSA:3.90.650.10 169 332 7.7E-50 T 18-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TWT_724 879c6d32cca170e85be4fe319378469a 337 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 336 36.918 T 18-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_724 879c6d32cca170e85be4fe319378469a 337 Gene3D G3DSA:3.30.1330.10 2 168 9.3E-59 T 18-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TWT_724 879c6d32cca170e85be4fe319378469a 337 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 325 1.9E-101 T 18-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_724 879c6d32cca170e85be4fe319378469a 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 162 4.6E-16 T 18-10-2018 IPR016188 PurM-like, N-terminal domain TWT_724 879c6d32cca170e85be4fe319378469a 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 328 1.0E-21 T 18-10-2018 IPR010918 PurM-like, C-terminal domain TWT_038 e1f4a161e3026c448fe569ae6e162aa5 242 Pfam PF00535 Glycosyl transferase family 2 7 150 6.3E-23 T 18-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TWT_038 e1f4a161e3026c448fe569ae6e162aa5 242 SUPERFAMILY SSF53448 4 211 5.14E-30 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_038 e1f4a161e3026c448fe569ae6e162aa5 242 Gene3D G3DSA:3.90.550.10 2 238 7.4E-35 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_452 a841606ea18aa44c500290bab236c9d7 316 SUPERFAMILY SSF56349 28 306 1.03E-46 T 18-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TWT_452 a841606ea18aa44c500290bab236c9d7 316 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 24 316 52.722 T 18-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TWT_452 a841606ea18aa44c500290bab236c9d7 316 Gene3D G3DSA:1.10.443.10 132 309 1.5E-49 T 18-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TWT_452 a841606ea18aa44c500290bab236c9d7 316 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 26 111 1.0E-14 T 18-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TWT_452 a841606ea18aa44c500290bab236c9d7 316 Pfam PF00589 Phage integrase family 133 301 4.8E-36 T 18-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TWT_452 a841606ea18aa44c500290bab236c9d7 316 Gene3D G3DSA:1.10.150.130 23 120 1.8E-18 T 18-10-2018 IPR010998 Integrase/recombinase, N-terminal TWT_790 55ee20274c6e9b62981f0689b075d5bb 370 Gene3D G3DSA:3.40.50.970 1 363 3.0E-92 T 18-10-2018 TWT_790 55ee20274c6e9b62981f0689b075d5bb 370 SUPERFAMILY SSF52518 29 362 2.46E-81 T 18-10-2018 IPR029061 Thiamin diphosphate-binding fold TWT_790 55ee20274c6e9b62981f0689b075d5bb 370 Pfam PF00676 Dehydrogenase E1 component 47 310 2.2E-62 T 18-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TWT_790 55ee20274c6e9b62981f0689b075d5bb 370 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 8 362 3.3E-125 T 18-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TWT_031 3f18c15b9c643d99aef013590848051b 207 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 1.0E-101 T 18-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TWT_031 3f18c15b9c643d99aef013590848051b 207 Gene3D G3DSA:2.60.120.10 1 201 1.3E-62 T 18-10-2018 IPR014710 RmlC-like jelly roll fold TWT_031 3f18c15b9c643d99aef013590848051b 207 SUPERFAMILY SSF51182 2 193 3.88E-63 T 18-10-2018 IPR011051 RmlC-like cupin domain superfamily TWT_031 3f18c15b9c643d99aef013590848051b 207 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 3.0E-54 T 18-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TWT_756 698dd082926c5ac09dcd8ebce16d4446 228 Pfam PF00578 AhpC/TSA family 88 197 5.4E-18 T 18-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TWT_756 698dd082926c5ac09dcd8ebce16d4446 228 Gene3D G3DSA:3.40.30.10 72 216 6.2E-31 T 18-10-2018 TWT_756 698dd082926c5ac09dcd8ebce16d4446 228 SUPERFAMILY SSF52833 85 213 9.23E-29 T 18-10-2018 IPR036249 Thioredoxin-like superfamily TWT_796 655d7c68c2d0d84ff04d07906a630093 134 SUPERFAMILY SSF82697 50 125 4.88E-19 T 18-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_796 655d7c68c2d0d84ff04d07906a630093 134 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 53 130 16.469 T 18-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_796 655d7c68c2d0d84ff04d07906a630093 134 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 54 126 3.6E-18 T 18-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_796 655d7c68c2d0d84ff04d07906a630093 134 Gene3D G3DSA:3.30.1280.10 53 133 3.2E-16 T 18-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TWT_796 655d7c68c2d0d84ff04d07906a630093 134 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 62 121 4.0E-29 T 18-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TWT_300 9940685c50248cb01d5915daa80e82ea 337 Gene3D G3DSA:3.30.360.10 154 317 3.8E-139 T 18-10-2018 TWT_300 9940685c50248cb01d5915daa80e82ea 337 SUPERFAMILY SSF55347 155 316 6.85E-66 T 18-10-2018 TWT_300 9940685c50248cb01d5915daa80e82ea 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 6.5E-60 T 18-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PIRSF PIRSF000149 1 336 2.6E-123 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 Gene3D G3DSA:3.40.50.720 4 328 3.8E-139 T 18-10-2018 TWT_300 9940685c50248cb01d5915daa80e82ea 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 105 3.7E-32 T 18-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 3.2E-38 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 3.2E-38 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 3.2E-38 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 3.2E-38 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 3.2E-38 T 18-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 SUPERFAMILY SSF51735 2 182 6.06E-56 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_300 9940685c50248cb01d5915daa80e82ea 337 SMART SM00846 3 155 5.4E-81 T 18-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 7.4E-124 T 18-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_300 9940685c50248cb01d5915daa80e82ea 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 18-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_522 75b68c90a9dcd222caca681e1796f001 452 SUPERFAMILY SSF55920 190 448 7.46E-64 T 18-10-2018 IPR036005 Creatinase/aminopeptidase-like TWT_522 75b68c90a9dcd222caca681e1796f001 452 Pfam PF05195 Aminopeptidase P, N-terminal domain 42 154 7.6E-16 T 18-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TWT_522 75b68c90a9dcd222caca681e1796f001 452 Pfam PF00557 Metallopeptidase family M24 196 425 3.2E-51 T 18-10-2018 IPR000994 Peptidase M24 TWT_522 75b68c90a9dcd222caca681e1796f001 452 Gene3D G3DSA:3.90.230.10 187 452 3.0E-76 T 18-10-2018 TWT_522 75b68c90a9dcd222caca681e1796f001 452 SUPERFAMILY SSF53092 39 188 4.87E-21 T 18-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TWT_522 75b68c90a9dcd222caca681e1796f001 452 SMART SM01011 35 172 1.8E-25 T 18-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TWT_522 75b68c90a9dcd222caca681e1796f001 452 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 361 373 - T 18-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TWT_437 6b8b220f2db0396901864fee699995e4 335 Pfam PF00288 GHMP kinases N terminal domain 87 150 4.1E-9 T 18-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TWT_437 6b8b220f2db0396901864fee699995e4 335 Pfam PF08544 GHMP kinases C terminal 250 304 1.9E-5 T 18-10-2018 IPR013750 GHMP kinase, C-terminal domain TWT_437 6b8b220f2db0396901864fee699995e4 335 TIGRFAM TIGR00191 thrB: homoserine kinase 11 324 4.8E-60 T 18-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TWT_437 6b8b220f2db0396901864fee699995e4 335 SUPERFAMILY SSF54211 10 158 2.66E-27 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_437 6b8b220f2db0396901864fee699995e4 335 Gene3D G3DSA:3.30.230.10 9 172 1.6E-41 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_437 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 196 213 1.3E-28 T 18-10-2018 TWT_437 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 273 288 1.3E-28 T 18-10-2018 TWT_437 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 137 150 1.3E-28 T 18-10-2018 TWT_437 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 100 115 1.3E-28 T 18-10-2018 TWT_437 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 18 33 1.3E-28 T 18-10-2018 TWT_437 6b8b220f2db0396901864fee699995e4 335 PIRSF PIRSF000676 7 326 2.0E-86 T 18-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TWT_437 6b8b220f2db0396901864fee699995e4 335 Gene3D G3DSA:3.30.70.890 188 307 5.7E-29 T 18-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TWT_437 6b8b220f2db0396901864fee699995e4 335 Hamap MF_00384 Homoserine kinase [thrB]. 13 325 26.415 T 18-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TWT_437 6b8b220f2db0396901864fee699995e4 335 SUPERFAMILY SSF55060 191 292 3.6E-23 T 18-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 252 375 1.1E-16 T 18-10-2018 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 344 2.1E-8 T 18-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 250 372 8.37E-10 T 18-10-2018 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 1 118 2.88E-22 T 18-10-2018 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 SMART SM00480 17 371 4.2E-55 T 18-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 359 1.3E-66 T 18-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 PIRSF PIRSF000804 1 373 2.1E-69 T 18-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 128 248 2.49E-16 T 18-10-2018 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 124 250 7.7E-24 T 18-10-2018 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 128 245 3.0E-22 T 18-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 1.5E-22 T 18-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TWT_002 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 1 120 8.8E-33 T 18-10-2018 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 2 65 15.121 T 18-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 Pfam PF01632 Ribosomal protein L35 3 63 1.2E-21 T 18-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 SUPERFAMILY SSF143034 3 64 1.7E-19 T 18-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 3 64 5.1E-20 T 18-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 6 32 - T 18-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 Gene3D G3DSA:2.40.50.530 2 64 2.1E-18 T 18-10-2018 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 PRINTS PR00064 Ribosomal protein L35 signature 37 55 2.5E-12 T 18-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 PRINTS PR00064 Ribosomal protein L35 signature 22 36 2.5E-12 T 18-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TWT_165 b4f5101436dfa4dfde81aeffec0c4a98 65 PRINTS PR00064 Ribosomal protein L35 signature 4 21 2.5E-12 T 18-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TWT_013 b3e1e59c9f7f8dc259dc3decb9901359 291 Gene3D G3DSA:3.30.2010.10 68 158 1.8E-31 T 18-10-2018 TWT_013 b3e1e59c9f7f8dc259dc3decb9901359 291 Hamap MF_00188 Protease HtpX [htpX]. 8 287 27.287 T 18-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TWT_013 b3e1e59c9f7f8dc259dc3decb9901359 291 Pfam PF01435 Peptidase family M48 76 287 4.0E-37 T 18-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TWT_585 97b8d6e93d155fe8a4916e400db3e51e 183 Pfam PF11377 Protein of unknown function (DUF3180) 43 173 1.2E-18 T 18-10-2018 IPR021517 Protein of unknown function DUF3180 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 SUPERFAMILY SSF52540 8 237 6.6E-51 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 Gene3D G3DSA:3.40.50.300 5 247 7.8E-51 T 18-10-2018 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 SUPERFAMILY SSF52540 280 502 8.05E-40 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 Pfam PF00005 ABC transporter 286 442 2.2E-19 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 Pfam PF00005 ABC transporter 24 179 1.3E-26 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 Gene3D G3DSA:3.40.50.300 268 515 2.1E-37 T 18-10-2018 TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 SMART SM00382 33 227 1.3E-6 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_330 25e6e0c874dc589519f8ae83b2326ce5 518 SMART SM00382 294 493 0.049 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_460 d497e435cfe9d110041c9b255d441c8b 76 Pfam PF13083 KH domain 7 61 1.6E-13 T 18-10-2018 TWT_460 d497e435cfe9d110041c9b255d441c8b 76 Gene3D G3DSA:3.30.1370.10 23 64 2.9E-5 T 18-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TWT_460 d497e435cfe9d110041c9b255d441c8b 76 SUPERFAMILY SSF54814 13 60 7.19E-7 T 18-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TWT_643 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF02601 Exonuclease VII, large subunit 136 333 9.4E-52 T 18-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TWT_643 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF02601 Exonuclease VII, large subunit 338 400 6.1E-10 T 18-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TWT_643 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF13742 OB-fold nucleic acid binding domain 22 106 3.5E-9 T 18-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 TWT_643 13c4d88945354d649f9d23e4ce27cfc3 404 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 18 403 19.064 T 18-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TWT_643 13c4d88945354d649f9d23e4ce27cfc3 404 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 22 402 5.5E-100 T 18-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 15 803 19.967 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Gene3D G3DSA:1.10.730.10 593 740 1.3E-25 T 18-10-2018 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Gene3D G3DSA:3.10.20.590 744 803 1.7E-14 T 18-10-2018 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Gene3D G3DSA:3.40.50.620 47 567 1.4E-212 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 SUPERFAMILY SSF52374 14 616 4.69E-132 T 18-10-2018 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 16 566 6.5E-225 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 SUPERFAMILY SSF47323 616 804 9.16E-20 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 65 - T 18-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Gene3D G3DSA:3.90.740.10 242 408 1.4E-212 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Gene3D G3DSA:2.30.210.10 568 585 1.4E-212 T 18-10-2018 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 235 373 2.3E-42 T 18-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 SUPERFAMILY SSF50677 237 412 2.62E-35 T 18-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 553 563 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 139 156 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 198 211 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 481 499 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 520 542 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 165 181 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 229 248 1.0E-52 T 18-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 410 610 8.9E-22 T 18-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Pfam PF08264 Anticodon-binding domain of tRNA 646 765 1.4E-12 T 18-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TWT_385 c7e1bf8039eadc43a4053dad66b24475 806 Pfam PF09334 tRNA synthetases class I (M) 53 183 3.3E-16 T 18-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_066 2c3ba5b1c19a0a048a30cdb743b56a32 74 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 58 1.2E-10 T 18-10-2018 IPR027379 Cardiolipin synthase N-terminal TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 Gene3D G3DSA:3.40.50.1440 3 220 1.7E-77 T 18-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 18-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 SUPERFAMILY SSF52490 12 208 2.62E-65 T 18-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 18-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 SMART SM00864 13 205 1.1E-105 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 5.2E-37 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 Gene3D G3DSA:3.30.1330.20 221 324 2.5E-36 T 18-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 353 37.773 T 18-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 SMART SM00865 207 324 7.7E-52 T 18-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 317 7.6E-123 T 18-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 SUPERFAMILY SSF55307 204 317 1.1E-41 T 18-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 Pfam PF12327 FtsZ family, C-terminal domain 222 316 3.9E-33 T 18-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-50 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-50 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-50 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_515 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-50 T 18-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TWT_160 ea801d1ade5dc04194dea9a62fa1dfe9 876 SUPERFAMILY SSF53448 34 254 4.95E-12 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_160 ea801d1ade5dc04194dea9a62fa1dfe9 876 Gene3D G3DSA:3.90.550.10 32 256 2.4E-8 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_160 ea801d1ade5dc04194dea9a62fa1dfe9 876 Gene3D G3DSA:3.40.50.2000 617 799 4.1E-17 T 18-10-2018 TWT_160 ea801d1ade5dc04194dea9a62fa1dfe9 876 Pfam PF00534 Glycosyl transferases group 1 622 795 3.0E-10 T 18-10-2018 IPR001296 Glycosyl transferase, family 1 TWT_160 ea801d1ade5dc04194dea9a62fa1dfe9 876 SUPERFAMILY SSF53756 426 813 5.34E-19 T 18-10-2018 TWT_246 c2afd9cf16681a09fa5731272a230459 207 Gene3D G3DSA:1.20.120.80 15 207 6.0E-50 T 18-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_246 c2afd9cf16681a09fa5731272a230459 207 Pfam PF00510 Cytochrome c oxidase subunit III 11 206 3.4E-23 T 18-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_246 c2afd9cf16681a09fa5731272a230459 207 SUPERFAMILY SSF81452 9 206 3.01E-50 T 18-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 SUPERFAMILY SSF52540 6 355 1.12E-42 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 363 77.747 T 18-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 Gene3D G3DSA:3.40.50.300 9 338 6.1E-92 T 18-10-2018 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 340 4.8E-21 T 18-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 ProSitePatterns PS00618 RecF protein signature 2. 304 322 - T 18-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 Gene3D G3DSA:1.20.1050.90 122 303 6.1E-92 T 18-10-2018 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 6 342 9.9E-87 T 18-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TWT_003 f05d0a05edf03b08e7f72243dcbd5d37 363 ProSitePatterns PS00617 RecF protein signature 1. 119 139 - T 18-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 271 507 4.7E-56 T 18-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 Gene3D G3DSA:3.30.70.3400 44 128 5.2E-17 T 18-10-2018 TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 8 530 34.948 T 18-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 44 514 4.5E-94 T 18-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 SUPERFAMILY SSF82866 321 518 1.7E-32 T 18-10-2018 TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 Pfam PF02355 Protein export membrane protein 343 519 2.1E-13 T 18-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TWT_271 c9b285663c8a63b1a868c0f015e6bc3e 559 Gene3D G3DSA:3.30.1360.200 209 340 2.6E-19 T 18-10-2018 TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 Hamap MF_00023 SsrA-binding protein [smpB]. 1 173 54.779 T 18-10-2018 IPR000037 SsrA-binding protein GO:0003723 TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 SUPERFAMILY SSF74982 23 150 8.63E-45 T 18-10-2018 IPR023620 Small protein B TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 Gene3D G3DSA:2.40.280.10 21 147 7.6E-42 T 18-10-2018 IPR023620 Small protein B TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 TIGRFAM TIGR00086 smpB: SsrA-binding protein 26 168 3.5E-55 T 18-10-2018 IPR000037 SsrA-binding protein GO:0003723 TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 ProSitePatterns PS01317 SsrA-binding protein. 45 57 - T 18-10-2018 IPR020081 SsrA-binding protein, conserved site TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 Pfam PF01668 SmpB protein 27 168 5.7E-50 T 18-10-2018 IPR000037 SsrA-binding protein GO:0003723 TWT_201 3b0c1a999bdd347d2ef0b0fbc7ff0566 211 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 27 150 1.0E-67 T 18-10-2018 IPR000037 SsrA-binding protein GO:0003723 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 SUPERFAMILY SSF56024 313 481 1.12E-40 T 18-10-2018 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 SUPERFAMILY SSF56024 76 326 8.3E-46 T 18-10-2018 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 17 497 1.1E-97 T 18-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 57 1.2E-5 T 18-10-2018 IPR027379 Cardiolipin synthase N-terminal TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 Gene3D G3DSA:3.30.870.10 307 464 3.5E-24 T 18-10-2018 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 Gene3D G3DSA:3.30.870.10 108 306 4.4E-37 T 18-10-2018 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 SMART SM00155 411 438 0.0036 T 18-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 SMART SM00155 214 241 0.036 T 18-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 Pfam PF13091 PLD-like domain 341 460 1.8E-24 T 18-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TWT_064 455b4fd67c85e4b1da492bb8d7f734ef 498 Pfam PF13091 PLD-like domain 129 237 2.3E-13 T 18-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 Gene3D G3DSA:2.30.30.100 198 243 2.5E-10 T 18-10-2018 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 Pfam PF02237 Biotin protein ligase C terminal domain 197 241 4.2E-7 T 18-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 Gene3D G3DSA:3.30.930.10 3 183 5.7E-44 T 18-10-2018 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 241 1.8E-40 T 18-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 Pfam PF03099 Biotin/lipoate A/B protein ligase family 11 133 7.4E-15 T 18-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TWT_024 dcd9f40745d0c1c208e4834be961df13 248 SUPERFAMILY SSF55681 3 173 6.71E-40 T 18-10-2018 TWT_117 efea71848275578c263a8b7d59e3a12e 697 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 422 664 9.5E-65 T 18-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related TWT_648 d094596cebaebf69364084c590dd7db2 284 Pfam PF01261 Xylose isomerase-like TIM barrel 22 227 1.6E-27 T 18-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TWT_648 d094596cebaebf69364084c590dd7db2 284 SUPERFAMILY SSF51658 14 268 2.49E-42 T 18-10-2018 IPR036237 Xylose isomerase-like superfamily TWT_648 d094596cebaebf69364084c590dd7db2 284 Gene3D G3DSA:3.20.20.150 1 280 3.0E-65 T 18-10-2018 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 432 3.2E-58 T 18-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 7 441 34.309 T 18-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 Gene3D G3DSA:3.65.10.10 27 239 3.8E-134 T 18-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 Gene3D G3DSA:3.65.10.10 12 436 3.8E-134 T 18-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 SUPERFAMILY SSF55205 8 438 2.45E-109 T 18-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TWT_508 7de2a4784bc86658fabd5ed37b98cc46 441 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9 437 1.1E-125 T 18-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TWT_797 d0014f43524464dcc42b603b9bacd6c3 405 Gene3D G3DSA:3.40.50.2000 191 385 7.3E-92 T 18-10-2018 TWT_797 d0014f43524464dcc42b603b9bacd6c3 405 SUPERFAMILY SSF53756 22 403 9.42E-68 T 18-10-2018 TWT_797 d0014f43524464dcc42b603b9bacd6c3 405 Gene3D G3DSA:3.40.50.2000 7 401 7.3E-92 T 18-10-2018 TWT_797 d0014f43524464dcc42b603b9bacd6c3 405 Pfam PF13439 Glycosyltransferase Family 4 23 194 3.4E-22 T 18-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TWT_797 d0014f43524464dcc42b603b9bacd6c3 405 Pfam PF00534 Glycosyl transferases group 1 223 379 6.0E-29 T 18-10-2018 IPR001296 Glycosyl transferase, family 1 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 Pfam PF00313 'Cold-shock' DNA-binding domain 4 58 3.7E-7 T 18-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-5 T 18-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 38 56 1.2E-5 T 18-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-5 T 18-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 Gene3D G3DSA:2.40.50.140 3 65 2.0E-12 T 18-10-2018 TWT_048 71289754180d32eebe1d22fd0e4c136a 125 SUPERFAMILY SSF50249 1 64 2.69E-11 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_048 71289754180d32eebe1d22fd0e4c136a 125 SMART SM00357 3 65 5.4E-5 T 18-10-2018 IPR011129 Cold shock domain GO:0003676 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Gene3D G3DSA:1.10.286.20 192 238 1.8E-30 T 18-10-2018 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Gene3D G3DSA:1.10.8.10 1 55 4.9E-18 T 18-10-2018 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Pfam PF00889 Elongation factor TS 71 272 1.3E-50 T 18-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Gene3D G3DSA:3.30.479.20 161 272 1.8E-30 T 18-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 SUPERFAMILY SSF54713 58 272 2.45E-37 T 18-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 SUPERFAMILY SSF46934 3 55 1.79E-12 T 18-10-2018 IPR009060 UBA-like superfamily GO:0005515 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 18-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Gene3D G3DSA:3.30.479.20 57 145 1.9E-14 T 18-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 Hamap MF_00050 Elongation factor Ts [tsf]. 1 273 51.485 T 18-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_448 c04761ca4bc9c7f8bb63df2dfd4d5162 273 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 3 272 1.0E-61 T 18-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 Gene3D G3DSA:3.40.50.720 162 301 2.3E-91 T 18-10-2018 TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 Pfam PF13823 Alcohol dehydrogenase GroES-associated 4 25 1.1E-5 T 18-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 8.5E-26 T 18-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 18-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 SUPERFAMILY SSF51735 149 316 1.26E-33 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 SUPERFAMILY SSF50129 4 163 1.67E-48 T 18-10-2018 IPR011032 GroES-like superfamily TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 Pfam PF00107 Zinc-binding dehydrogenase 185 305 1.3E-24 T 18-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TWT_326 d528d6562cc1d8f7b6882c3ee3fa0ed7 357 Gene3D G3DSA:3.90.180.10 18 342 2.3E-91 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:1.10.8.60 722 818 4.2E-25 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:1.10.8.60 356 489 1.0E-42 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:3.40.50.300 160 351 1.5E-71 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 801 4.0E-24 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SUPERFAMILY SSF52540 169 465 1.68E-74 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SMART SM00382 208 348 1.9E-10 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SMART SM00382 545 684 1.7E-13 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 213 325 5.6E-14 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SUPERFAMILY SSF52540 494 801 1.03E-77 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:4.10.860.10 417 475 1.0E-42 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 20 72 2.1E-15 T 18-10-2018 IPR004176 Clp, N-terminal TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 145 5.4E-14 T 18-10-2018 IPR004176 Clp, N-terminal TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:1.10.1780.10 5 153 1.4E-58 T 18-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SUPERFAMILY SSF81923 7 148 1.02E-30 T 18-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 SMART SM01086 722 811 1.7E-31 T 18-10-2018 IPR019489 Clp ATPase, C-terminal TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Gene3D G3DSA:3.40.50.300 498 720 3.9E-83 T 18-10-2018 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 716 1.0E-50 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 1.1E-40 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 1.1E-40 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 1.1E-40 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_065 470487b1658e7fc183ec42efb69c63ef 840 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 1.1E-40 T 18-10-2018 IPR001270 ClpA/B family GO:0005524 TWT_305 89b3a29aa316098a7c4566604b7996af 93 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 22 80 3.2E-15 T 18-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_305 89b3a29aa316098a7c4566604b7996af 93 SUPERFAMILY SSF51713 20 83 1.2E-16 T 18-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_305 89b3a29aa316098a7c4566604b7996af 93 Gene3D G3DSA:3.20.20.105 15 92 3.1E-18 T 18-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TWT_335 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 Pfam PF00355 Rieske [2Fe-2S] domain 2 87 2.2E-20 T 18-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TWT_335 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 SUPERFAMILY SSF50022 2 99 6.81E-31 T 18-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TWT_335 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 Gene3D G3DSA:2.102.10.10 1 99 3.3E-32 T 18-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 Gene3D G3DSA:3.40.50.300 480 697 1.1E-33 T 18-10-2018 TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 SMART SM00487 215 399 2.2E-16 T 18-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 Pfam PF00271 Helicase conserved C-terminal domain 530 629 3.0E-11 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 SMART SM00490 546 629 1.2E-10 T 18-10-2018 IPR001650 Helicase, C-terminal TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 Gene3D G3DSA:3.40.50.10810 210 447 7.4E-26 T 18-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 SUPERFAMILY SSF52540 324 671 7.51E-36 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 SUPERFAMILY SSF52540 218 384 6.01E-31 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_118 0b4d4ed021fcca605d04103d59842c3c 698 Pfam PF00176 SNF2 family N-terminal domain 237 445 3.8E-18 T 18-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 SUPERFAMILY SSF116842 52 105 5.36E-14 T 18-10-2018 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 53 104 5.6E-16 T 18-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 Gene3D G3DSA:1.10.287.1040 50 120 1.1E-10 T 18-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 53 94 2.0E-17 T 18-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 53 113 11.674 T 18-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TWT_644 20f8bd927ce8fa5236641b24c0047ee1 121 Pfam PF02609 Exonuclease VII small subunit 54 103 5.7E-14 T 18-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 155 19.514 T 18-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 Gene3D G3DSA:3.40.390.30 14 150 9.2E-30 T 18-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 Pfam PF02130 Uncharacterized protein family UPF0054 35 144 2.1E-28 T 18-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 144 7.8E-26 T 18-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 SUPERFAMILY SSF55486 19 143 3.57E-30 T 18-10-2018 TWT_283 87a5857a4df3df2edb22106adcf913ce 171 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 115 125 - T 18-10-2018 IPR020549 Endoribonuclease YbeY, conserved site TWT_808 122ba318510221529859a5eefb53a123 50 ProSitePatterns PS00784 Ribosomal protein L34 signature. 8 27 - T 18-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_808 122ba318510221529859a5eefb53a123 50 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 8 50 6.9E-19 T 18-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_808 122ba318510221529859a5eefb53a123 50 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 7 50 15.222 T 18-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_808 122ba318510221529859a5eefb53a123 50 Pfam PF00468 Ribosomal protein L34 8 50 3.7E-20 T 18-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_808 122ba318510221529859a5eefb53a123 50 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 8 48 1.0E-8 T 18-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_706 a5ce8d564fe5a551c840043f7e129f88 294 Gene3D G3DSA:3.60.21.10 46 247 3.3E-14 T 18-10-2018 IPR029052 Metallo-dependent phosphatase-like TWT_706 a5ce8d564fe5a551c840043f7e129f88 294 SUPERFAMILY SSF56300 43 284 3.17E-24 T 18-10-2018 TWT_706 a5ce8d564fe5a551c840043f7e129f88 294 Pfam PF00149 Calcineurin-like phosphoesterase 47 230 4.0E-8 T 18-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TWT_332 c1aa0d504528f8a8ccd9ba45f835398d 285 Pfam PF02104 SURF1 family 30 242 3.5E-27 T 18-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 Gene3D G3DSA:1.10.287.10 58 142 2.9E-31 T 18-10-2018 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 60 142 2.6E-34 T 18-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 SMART SM01387 61 141 1.8E-46 T 18-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 64 141 4.0E-28 T 18-10-2018 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 Pfam PF00312 Ribosomal protein S15 63 141 8.3E-34 T 18-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 SUPERFAMILY SSF47060 59 142 3.24E-31 T 18-10-2018 IPR009068 S15/NS1, RNA-binding TWT_422 fd79ece26e6f0e5f2580212c52fbdd36 142 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 48 142 21.215 T 18-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Gene3D G3DSA:3.90.1150.10 782 917 9.8E-34 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Pfam PF02347 Glycine cleavage system P-protein 3 413 8.3E-145 T 18-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 SUPERFAMILY SSF53383 493 964 6.12E-87 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 SUPERFAMILY SSF53383 4 365 2.82E-86 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Pfam PF00266 Aminotransferase class-V 591 737 4.3E-6 T 18-10-2018 IPR000192 Aminotransferase class V domain TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Gene3D G3DSA:3.40.640.10 537 757 3.5E-51 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Gene3D G3DSA:3.40.640.10 81 339 5.0E-93 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 968 23.096 T 18-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TWT_135 f538ab9c3bd0bc1a77ebd8d0d6455083 968 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 4 963 0.0 T 18-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TWT_684 17e89a72b1dea97f56f3e93b2544ebcd 408 Gene3D G3DSA:1.20.1250.20 203 390 1.6E-10 T 18-10-2018 TWT_684 17e89a72b1dea97f56f3e93b2544ebcd 408 Pfam PF07690 Major Facilitator Superfamily 33 273 4.9E-12 T 18-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TWT_684 17e89a72b1dea97f56f3e93b2544ebcd 408 SUPERFAMILY SSF103473 12 390 1.7E-30 T 18-10-2018 IPR036259 MFS transporter superfamily TWT_684 17e89a72b1dea97f56f3e93b2544ebcd 408 Gene3D G3DSA:1.20.1250.20 12 197 8.0E-11 T 18-10-2018 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 Gene3D G3DSA:3.20.20.70 8 370 2.3E-144 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 TIGRFAM TIGR00876 tal_mycobact: transaldolase 17 364 1.3E-117 T 18-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 Hamap MF_00493 Transaldolase [tal]. 1 370 134.144 T 18-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 21 364 1.9E-73 T 18-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 SUPERFAMILY SSF51569 10 369 4.03E-72 T 18-10-2018 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 ProSitePatterns PS01054 Transaldolase signature 1. 47 55 - T 18-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TWT_341 8798b3a1eac1c94063dcadefea435d3d 370 PIRSF PIRSF036915 5 370 1.2E-150 T 18-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TWT_556 01737e4656763252c3802f10f9e753ae 222 Pfam PF00448 SRP54-type protein, GTPase domain 22 221 2.2E-71 T 18-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_556 01737e4656763252c3802f10f9e753ae 222 Gene3D G3DSA:3.40.50.300 16 211 1.1E-72 T 18-10-2018 TWT_556 01737e4656763252c3802f10f9e753ae 222 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 195 208 - T 18-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_556 01737e4656763252c3802f10f9e753ae 222 SMART SM00962 22 222 5.6E-99 T 18-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TWT_556 01737e4656763252c3802f10f9e753ae 222 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 17 221 7.2E-86 T 18-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TWT_556 01737e4656763252c3802f10f9e753ae 222 SUPERFAMILY SSF52540 17 220 7.3E-48 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_556 01737e4656763252c3802f10f9e753ae 222 Gene3D G3DSA:1.20.120.140 212 222 1.1E-72 T 18-10-2018 TWT_556 01737e4656763252c3802f10f9e753ae 222 SMART SM00382 21 173 3.4E-7 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 PIRSF PIRSF000386 4 234 2.7E-84 T 18-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 SUPERFAMILY SSF75217 3 231 2.22E-83 T 18-10-2018 IPR029028 Alpha/beta knot methyltransferases TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 Gene3D G3DSA:1.10.1270.20 176 232 2.0E-24 T 18-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 Gene3D G3DSA:3.40.1280.10 2 175 4.6E-61 T 18-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 4 231 3.7E-73 T 18-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 25 222 2.6E-59 T 18-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TWT_458 2a4729bbda0aa37bb70a98017a8dbcee 234 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 234 85.695 T 18-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TWT_781 aa1f4c2e6d13f8ad57038c031df03a89 175 Pfam PF04417 Protein of unknown function (DUF501) 45 163 9.6E-34 T 18-10-2018 IPR007511 Protein of unknown function DUF501 TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 2.8E-38 T 18-10-2018 TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 SUPERFAMILY SSF52540 193 501 1.9E-36 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 SMART SM00382 213 396 4.9E-10 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 410 504 1.1E-16 T 18-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 SUPERFAMILY SSF54211 5 163 8.34E-34 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 399 7.5E-84 T 18-10-2018 IPR000523 Magnesium chelatase ChlI domain TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 Gene3D G3DSA:3.30.230.10 39 167 6.5E-17 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 504 1.7E-131 T 18-10-2018 IPR004482 Mg chelatase-related protein TWT_454 731eb1bd919b3b2cb0823f01901780d1 511 Gene3D G3DSA:3.40.50.300 194 508 1.8E-38 T 18-10-2018 TWT_526 3fde0bd0b8ab44c8e58130c64864aabe 315 Gene3D G3DSA:3.30.70.580 49 157 3.5E-28 T 18-10-2018 TWT_526 3fde0bd0b8ab44c8e58130c64864aabe 315 SUPERFAMILY SSF55120 50 303 5.18E-66 T 18-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_526 3fde0bd0b8ab44c8e58130c64864aabe 315 Pfam PF01416 tRNA pseudouridine synthase 196 298 1.0E-16 T 18-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_526 3fde0bd0b8ab44c8e58130c64864aabe 315 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 52 297 28.994 T 18-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TWT_526 3fde0bd0b8ab44c8e58130c64864aabe 315 Gene3D G3DSA:3.30.70.660 158 300 3.4E-28 T 18-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TWT_747 53d81107243fc3968506cd63aa2c1d01 130 Gene3D G3DSA:1.10.1660.10 3 116 5.6E-19 T 18-10-2018 TWT_747 53d81107243fc3968506cd63aa2c1d01 130 Pfam PF13411 MerR HTH family regulatory protein 8 72 4.4E-14 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_747 53d81107243fc3968506cd63aa2c1d01 130 SMART SM00422 7 75 8.2E-16 T 18-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TWT_747 53d81107243fc3968506cd63aa2c1d01 130 SUPERFAMILY SSF46955 7 91 3.11E-15 T 18-10-2018 IPR009061 Putative DNA-binding domain superfamily TWT_705 12dd5705da91aa75e650afa7e8237322 876 SMART SM00740 810 874 1.9E-11 T 18-10-2018 IPR005543 PASTA domain TWT_705 12dd5705da91aa75e650afa7e8237322 876 SMART SM00740 745 809 1.9E-10 T 18-10-2018 IPR005543 PASTA domain TWT_705 12dd5705da91aa75e650afa7e8237322 876 Pfam PF00905 Penicillin binding protein transpeptidase domain 401 670 1.5E-14 T 18-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TWT_705 12dd5705da91aa75e650afa7e8237322 876 SUPERFAMILY SSF53955 70 323 2.47E-55 T 18-10-2018 IPR023346 Lysozyme-like domain superfamily TWT_705 12dd5705da91aa75e650afa7e8237322 876 Gene3D G3DSA:3.40.710.10 348 746 1.5E-69 T 18-10-2018 TWT_705 12dd5705da91aa75e650afa7e8237322 876 Pfam PF03793 PASTA domain 814 874 3.3E-13 T 18-10-2018 IPR005543 PASTA domain TWT_705 12dd5705da91aa75e650afa7e8237322 876 Pfam PF03793 PASTA domain 748 807 1.1E-11 T 18-10-2018 IPR005543 PASTA domain TWT_705 12dd5705da91aa75e650afa7e8237322 876 Gene3D G3DSA:3.30.10.20 809 874 1.6E-11 T 18-10-2018 TWT_705 12dd5705da91aa75e650afa7e8237322 876 SUPERFAMILY SSF56601 284 750 3.17E-67 T 18-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TWT_705 12dd5705da91aa75e650afa7e8237322 876 Pfam PF00912 Transglycosylase 70 298 2.0E-48 T 18-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_705 12dd5705da91aa75e650afa7e8237322 876 Gene3D G3DSA:3.30.10.20 747 808 8.0E-12 T 18-10-2018 TWT_701 f189a9e6ae320d5117887c49a2b897d9 353 SUPERFAMILY SSF52540 44 321 6.68E-46 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_701 f189a9e6ae320d5117887c49a2b897d9 353 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 43 334 3.9E-113 T 18-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase TWT_701 f189a9e6ae320d5117887c49a2b897d9 353 Pfam PF00437 Type II/IV secretion system protein 48 323 2.5E-61 T 18-10-2018 IPR001482 Type II/IV secretion system protein TWT_701 f189a9e6ae320d5117887c49a2b897d9 353 Gene3D G3DSA:3.30.450.380 42 139 1.0E-19 T 18-10-2018 TWT_701 f189a9e6ae320d5117887c49a2b897d9 353 Gene3D G3DSA:3.40.50.300 146 346 4.0E-56 T 18-10-2018 TWT_740 254dc37b519ef3c9a84c8ff639a87e84 201 Gene3D G3DSA:2.60.40.1220 25 124 2.3E-14 T 18-10-2018 TWT_740 254dc37b519ef3c9a84c8ff639a87e84 201 Pfam PF04234 CopC domain 25 117 2.7E-16 T 18-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 TWT_740 254dc37b519ef3c9a84c8ff639a87e84 201 SUPERFAMILY SSF81296 24 117 8.4E-15 T 18-10-2018 IPR014756 Immunoglobulin E-set TWT_545 68ff5097127558b6c649b78968a5bebc 86 Gene3D G3DSA:2.40.50.140 7 86 4.4E-30 T 18-10-2018 TWT_545 68ff5097127558b6c649b78968a5bebc 86 SUPERFAMILY SSF50249 8 85 2.1E-27 T 18-10-2018 IPR012340 Nucleic acid-binding, OB-fold TWT_545 68ff5097127558b6c649b78968a5bebc 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 8 83 22.73 T 18-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 79 8.0E-31 T 18-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 8.3E-12 T 18-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 8.3E-12 T 18-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 8.3E-12 T 18-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 18-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_545 68ff5097127558b6c649b78968a5bebc 86 Pfam PF00366 Ribosomal protein S17 13 79 4.9E-27 T 18-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_545 68ff5097127558b6c649b78968a5bebc 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 79 4.0E-32 T 18-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_253 be31b050f9c8ff32f2e83cf07c238adf 367 Gene3D G3DSA:3.40.47.10 40 214 2.1E-55 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_253 be31b050f9c8ff32f2e83cf07c238adf 367 SUPERFAMILY SSF53901 45 361 2.09E-50 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_253 be31b050f9c8ff32f2e83cf07c238adf 367 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 152 225 3.0E-21 T 18-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TWT_253 be31b050f9c8ff32f2e83cf07c238adf 367 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 277 364 3.2E-24 T 18-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TWT_253 be31b050f9c8ff32f2e83cf07c238adf 367 Gene3D G3DSA:3.40.47.10 215 367 2.9E-33 T 18-10-2018 IPR016039 Thiolase-like GO:0003824 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 59 98 - T 18-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 16 346 2.3E-64 T 18-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 Gene3D G3DSA:3.40.140.10 14 140 3.0E-29 T 18-10-2018 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 Pfam PF01872 RibD C-terminal domain 153 345 7.5E-35 T 18-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 Gene3D G3DSA:3.40.430.10 147 352 8.2E-43 T 18-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 PIRSF PIRSF006769 7 354 4.2E-113 T 18-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 SUPERFAMILY SSF53597 151 349 1.68E-42 T 18-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 SUPERFAMILY SSF53927 15 144 7.1E-29 T 18-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TWT_687 d9d7c98b53889e7fb3e94c8965cd9685 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 109 1.4E-13 T 18-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 4 80 18.564 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 SUPERFAMILY SSF46911 7 78 6.8E-22 T 18-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 24 77 8.6E-21 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 5.6E-16 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 5.6E-16 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 5.6E-16 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 5.6E-16 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 18-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 Pfam PF01084 Ribosomal protein S18 26 74 1.8E-20 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 29 77 4.0E-11 T 18-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_106 7f80218e9f1fd0036e5f683ac6daf779 83 Gene3D G3DSA:4.10.640.10 3 82 4.0E-23 T 18-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_594 99d5afe14f83ba25910f1881136fee9d 133 Pfam PF05345 Putative Ig domain 75 109 1.2E-5 T 18-10-2018 IPR008009 Putative Ig TWT_577 5a1f119853d89704eb158c77404c80ed 194 Pfam PF01478 Type IV leader peptidase family 42 141 1.3E-7 T 18-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TWT_620 69477e018d8f5a142a4b5dfef16f78ea 224 Pfam PF09335 SNARE associated Golgi protein 52 177 6.8E-18 T 18-10-2018 IPR032816 SNARE associated Golgi protein TWT_560 d89c1afe46f14e5c8cd4cfae8d065db6 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 315 2.2E-46 T 18-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 Pfam PF11969 Scavenger mRNA decapping enzyme C-term binding 4 101 6.5E-17 T 18-10-2018 TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 PRINTS PR00332 Histidine triad family signature 4 20 1.7E-14 T 18-10-2018 IPR001310 Histidine triad (HIT) protein TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 PRINTS PR00332 Histidine triad family signature 90 100 1.7E-14 T 18-10-2018 IPR001310 Histidine triad (HIT) protein TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 PRINTS PR00332 Histidine triad family signature 25 43 1.7E-14 T 18-10-2018 IPR001310 Histidine triad (HIT) protein TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 Gene3D G3DSA:3.30.428.10 1 105 2.4E-25 T 18-10-2018 IPR036265 HIT-like superfamily TWT_282 bcb28dcc3e2b6b9de9cebee2542aa056 107 SUPERFAMILY SSF54197 2 102 2.01E-23 T 18-10-2018 IPR036265 HIT-like superfamily TWT_397 a1e9309243a1b2bc735d6519600e2363 155 PIRSF PIRSF005384 3 155 3.6E-42 T 18-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TWT_397 a1e9309243a1b2bc735d6519600e2363 155 Gene3D G3DSA:3.40.1400.10 2 155 1.3E-45 T 18-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TWT_397 a1e9309243a1b2bc735d6519600e2363 155 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 5 152 5.1E-44 T 18-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TWT_397 a1e9309243a1b2bc735d6519600e2363 155 SUPERFAMILY SSF89623 4 152 4.58E-45 T 18-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TWT_397 a1e9309243a1b2bc735d6519600e2363 155 Pfam PF02502 Ribose/Galactose Isomerase 5 148 6.4E-39 T 18-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TWT_397 a1e9309243a1b2bc735d6519600e2363 155 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 4 154 7.8E-71 T 18-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 20 485 4.8E-142 T 18-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 PIRSF PIRSF000485 17 502 6.6E-155 T 18-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 Pfam PF00156 Phosphoribosyl transferase domain 314 411 1.7E-7 T 18-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 SUPERFAMILY SSF56235 20 279 1.2E-64 T 18-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 19 485 43.686 T 18-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 Gene3D G3DSA:3.40.50.2020 299 463 6.2E-144 T 18-10-2018 TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 SUPERFAMILY SSF53271 272 502 1.97E-64 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 Gene3D G3DSA:3.60.20.10 20 434 6.2E-144 T 18-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TWT_723 208d65e2c4301951fe98b85fd70a71cf 504 Pfam PF13522 Glutamine amidotransferase domain 83 219 8.2E-18 T 18-10-2018 TWT_334 319b4f7d326a7aa9607e9ddf159a3932 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 1.5E-98 T 18-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TWT_334 319b4f7d326a7aa9607e9ddf159a3932 249 Gene3D G3DSA:3.40.50.300 1 245 1.6E-50 T 18-10-2018 TWT_334 319b4f7d326a7aa9607e9ddf159a3932 249 SUPERFAMILY SSF52540 3 232 1.3E-39 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_334 319b4f7d326a7aa9607e9ddf159a3932 249 Pfam PF00005 ABC transporter 23 174 8.1E-21 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_563 3dd7eb1f15441be3c50becf44cbb4876 65 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 65 11.426 T 18-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_563 3dd7eb1f15441be3c50becf44cbb4876 65 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 45 8.2E-10 T 18-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_563 3dd7eb1f15441be3c50becf44cbb4876 65 SUPERFAMILY SSF57829 2 37 5.49E-7 T 18-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TWT_563 3dd7eb1f15441be3c50becf44cbb4876 65 Pfam PF01783 Ribosomal L32p protein family 2 44 7.2E-10 T 18-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_783 a899e266b92a72b472e371302debeb6b 446 SUPERFAMILY SSF51604 157 437 1.63E-119 T 18-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TWT_783 a899e266b92a72b472e371302debeb6b 446 SMART SM01193 22 152 1.9E-88 T 18-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 Gene3D G3DSA:3.30.390.10 19 144 1.0E-52 T 18-10-2018 IPR029017 Enolase-like, N-terminal TWT_783 a899e266b92a72b472e371302debeb6b 446 Pfam PF03952 Enolase, N-terminal domain 22 152 3.4E-56 T 18-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 125 141 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 328 339 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 55 69 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 179 192 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 351 365 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PRINTS PR00148 Enolase signature 380 397 3.1E-45 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 SMART SM01192 157 442 1.1E-200 T 18-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 ProSitePatterns PS00164 Enolase signature. 351 364 - T 18-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TWT_783 a899e266b92a72b472e371302debeb6b 446 Hamap MF_00318 Enolase [eno]. 20 428 43.641 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 Gene3D G3DSA:3.20.20.120 146 444 1.5E-125 T 18-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TWT_783 a899e266b92a72b472e371302debeb6b 446 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 22 439 2.5E-197 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 SUPERFAMILY SSF54826 21 155 4.0E-54 T 18-10-2018 TWT_783 a899e266b92a72b472e371302debeb6b 446 Pfam PF00113 Enolase, C-terminal TIM barrel domain 159 436 5.8E-125 T 18-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_783 a899e266b92a72b472e371302debeb6b 446 PIRSF PIRSF001400 18 439 8.9E-184 T 18-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 Pfam PF06071 Protein of unknown function (DUF933) 260 342 4.9E-37 T 18-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 PIRSF PIRSF006641 1 344 2.5E-120 T 18-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:3.40.50.300 3 259 2.8E-117 T 18-10-2018 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:1.10.150.300 113 186 2.8E-117 T 18-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 342 2.6E-107 T 18-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 Pfam PF01926 50S ribosome-binding GTPase 5 115 9.7E-23 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 SUPERFAMILY SSF81271 260 341 1.57E-33 T 18-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 SUPERFAMILY SSF52540 3 282 4.94E-60 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_639 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.2E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.2E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.2E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.2E-35 T 18-10-2018 IPR006073 GTP binding domain GO:0005525 TWT_639 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:3.10.20.30 48 342 2.8E-117 T 18-10-2018 IPR012675 Beta-grasp domain superfamily TWT_646 7bca30077e402cad9017cd3e6e7b31cd 314 Gene3D G3DSA:3.40.1190.20 2 304 2.7E-71 T 18-10-2018 IPR029056 Ribokinase-like TWT_646 7bca30077e402cad9017cd3e6e7b31cd 314 SUPERFAMILY SSF53613 3 302 1.01E-60 T 18-10-2018 IPR029056 Ribokinase-like TWT_646 7bca30077e402cad9017cd3e6e7b31cd 314 Pfam PF00294 pfkB family carbohydrate kinase 7 297 1.7E-29 T 18-10-2018 IPR011611 Carbohydrate kinase PfkB TWT_442 b8f3d7de93b711fb41ef35e65c334696 212 Gene3D G3DSA:1.10.530.10 114 208 9.3E-6 T 18-10-2018 TWT_442 b8f3d7de93b711fb41ef35e65c334696 212 SUPERFAMILY SSF53955 137 205 4.22E-11 T 18-10-2018 IPR023346 Lysozyme-like domain superfamily TWT_442 b8f3d7de93b711fb41ef35e65c334696 212 Pfam PF01464 Transglycosylase SLT domain 137 198 1.3E-5 T 18-10-2018 IPR008258 Transglycosylase SLT domain 1 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 PIRSF PIRSF001456 1 385 2.3E-119 T 18-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 Gene3D G3DSA:3.60.150.10 1 399 1.3E-143 T 18-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 SUPERFAMILY SSF103263 1 390 3.79E-131 T 18-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 18-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 Hamap MF_00300 Chorismate synthase [aroC]. 2 375 33.162 T 18-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 18-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 1.1E-118 T 18-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_372 96a6f2b8d42a054393c5616b2f3efd34 400 Pfam PF01264 Chorismate synthase 2 368 5.4E-112 T 18-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 114 140 4.4E-17 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 164 192 4.4E-17 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 114 4.4E-17 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 4.4E-17 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 TIGRFAM TIGR01912 TatC-Arch: Sec-independent protein translocase TatC 18 249 6.1E-77 T 18-10-2018 IPR011532 Sec-independent protein translocase TatC, archaeal TWT_320 5e97adef8197af75f20a5bce318b94ab 255 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 232 1.1E-40 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_320 5e97adef8197af75f20a5bce318b94ab 255 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 249 11.343 T 18-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TWT_352 da824e6a1da113421794ffe685ab8636 269 Pfam PF00005 ABC transporter 33 187 8.4E-35 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_352 da824e6a1da113421794ffe685ab8636 269 SUPERFAMILY SSF52540 16 255 7.92E-61 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_352 da824e6a1da113421794ffe685ab8636 269 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_352 da824e6a1da113421794ffe685ab8636 269 Gene3D G3DSA:3.40.50.300 13 267 3.9E-69 T 18-10-2018 TWT_352 da824e6a1da113421794ffe685ab8636 269 SMART SM00382 41 249 8.7E-11 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_339 183f0bb7aee40308dfa601a22789cd2c 300 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 295 18.469 T 18-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TWT_339 183f0bb7aee40308dfa601a22789cd2c 300 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 66 88 - T 18-10-2018 IPR030470 UbiA prenyltransferase conserved site TWT_339 183f0bb7aee40308dfa601a22789cd2c 300 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 293 6.0E-89 T 18-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TWT_339 183f0bb7aee40308dfa601a22789cd2c 300 Pfam PF01040 UbiA prenyltransferase family 28 275 1.6E-61 T 18-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TWT_339 183f0bb7aee40308dfa601a22789cd2c 300 Gene3D G3DSA:1.10.357.140 24 194 2.8E-21 T 18-10-2018 TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 Pfam PF00327 Ribosomal protein L30p/L7e 9 59 1.4E-10 T 18-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 Gene3D G3DSA:3.30.1390.20 6 65 1.1E-19 T 18-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 6 63 17.031 T 18-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 9 63 1.0E-15 T 18-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 SUPERFAMILY SSF55129 8 64 1.23E-16 T 18-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TWT_537 7f14a0828ea65a1641606a7fe1ab12c2 65 PIRSF PIRSF002211 4 65 6.1E-25 T 18-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_707 71864f4efe62bf9b141b2b494b332031 337 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 235 249 - T 18-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_707 71864f4efe62bf9b141b2b494b332031 337 SUPERFAMILY SSF55347 125 321 1.76E-58 T 18-10-2018 TWT_707 71864f4efe62bf9b141b2b494b332031 337 Gene3D G3DSA:3.40.50.720 5 331 7.8E-119 T 18-10-2018 TWT_707 71864f4efe62bf9b141b2b494b332031 337 Gene3D G3DSA:3.30.360.10 124 321 7.8E-119 T 18-10-2018 TWT_707 71864f4efe62bf9b141b2b494b332031 337 SUPERFAMILY SSF51735 2 152 1.69E-42 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_707 71864f4efe62bf9b141b2b494b332031 337 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 333 3.9E-116 T 18-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TWT_707 71864f4efe62bf9b141b2b494b332031 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 135 320 1.3E-42 T 18-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TWT_707 71864f4efe62bf9b141b2b494b332031 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 115 1.2E-27 T 18-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TWT_707 71864f4efe62bf9b141b2b494b332031 337 PIRSF PIRSF000148 1 337 4.0E-108 T 18-10-2018 TWT_707 71864f4efe62bf9b141b2b494b332031 337 SMART SM00859 3 116 4.5E-34 T 18-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TWT_315 a9069fba7996aa901e645b5e82e23a4f 279 Pfam PF02673 Bacitracin resistance protein BacA 5 271 1.3E-66 T 18-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TWT_315 a9069fba7996aa901e645b5e82e23a4f 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 277 16.13 T 18-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TWT_628 5115fecdcdf7e356e5f412392a90d472 358 Gene3D G3DSA:2.30.42.10 133 222 8.2E-7 T 18-10-2018 TWT_628 5115fecdcdf7e356e5f412392a90d472 358 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 251 324 2.7E-6 T 18-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TWT_628 5115fecdcdf7e356e5f412392a90d472 358 SUPERFAMILY SSF50156 157 250 6.44E-10 T 18-10-2018 IPR036034 PDZ superfamily GO:0005515 TWT_628 5115fecdcdf7e356e5f412392a90d472 358 Gene3D G3DSA:3.30.230.10 224 353 1.0E-14 T 18-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TWT_628 5115fecdcdf7e356e5f412392a90d472 358 SUPERFAMILY SSF54211 235 343 3.45E-16 T 18-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Gene3D G3DSA:3.40.50.300 149 331 5.2E-68 T 18-10-2018 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 18-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 329 3.3E-45 T 18-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Pfam PF01434 Peptidase family M41 393 600 4.7E-76 T 18-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 SUPERFAMILY SSF140990 412 610 3.4E-67 T 18-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Gene3D G3DSA:1.10.8.60 332 406 3.1E-26 T 18-10-2018 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 SUPERFAMILY SSF52540 153 402 2.93E-71 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_588 0776f4a375ec2d19d36898eb785014f1 666 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 601 3.4E-219 T 18-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 610 36.007 T 18-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TWT_588 0776f4a375ec2d19d36898eb785014f1 666 SMART SM00382 194 333 9.8E-25 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_588 0776f4a375ec2d19d36898eb785014f1 666 Gene3D G3DSA:1.20.58.760 407 608 2.6E-68 T 18-10-2018 TWT_469 e3a659de8c3c967ba40febae281b4166 201 Gene3D G3DSA:3.40.50.620 10 199 3.9E-62 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_469 e3a659de8c3c967ba40febae281b4166 201 Pfam PF01467 Cytidylyltransferase-like 15 171 3.9E-26 T 18-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TWT_469 e3a659de8c3c967ba40febae281b4166 201 SUPERFAMILY SSF52374 12 198 7.51E-54 T 18-10-2018 TWT_469 e3a659de8c3c967ba40febae281b4166 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 11 197 30.793 T 18-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TWT_469 e3a659de8c3c967ba40febae281b4166 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 72 3.2E-9 T 18-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TWT_469 e3a659de8c3c967ba40febae281b4166 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 15 196 5.0E-52 T 18-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TWT_659 7aeec6430241a9bd8c796c513d4fb9e8 336 SUPERFAMILY SSF55729 86 327 8.68E-27 T 18-10-2018 IPR016181 Acyl-CoA N-acyltransferase TWT_659 7aeec6430241a9bd8c796c513d4fb9e8 336 Pfam PF00583 Acetyltransferase (GNAT) family 239 321 2.3E-11 T 18-10-2018 IPR000182 GNAT domain TWT_659 7aeec6430241a9bd8c796c513d4fb9e8 336 Gene3D G3DSA:3.40.630.30 10 333 4.3E-46 T 18-10-2018 TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 18-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 Pfam PF01174 SNO glutamine amidotransferase family 5 183 1.2E-52 T 18-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 185 34.857 T 18-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 PIRSF PIRSF005639 1 188 4.6E-68 T 18-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 SUPERFAMILY SSF52317 2 185 2.29E-46 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 Gene3D G3DSA:3.40.50.880 1 187 7.8E-66 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_265 c7c3d2ab79551fac0f284c798984ab35 188 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 183 4.3E-62 T 18-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TWT_663 42c5e8140494886d5d0c3a8ab84606c9 276 Gene3D G3DSA:3.40.50.300 7 258 3.5E-54 T 18-10-2018 TWT_663 42c5e8140494886d5d0c3a8ab84606c9 276 SUPERFAMILY SSF52540 11 228 2.72E-49 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_663 42c5e8140494886d5d0c3a8ab84606c9 276 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 18-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TWT_663 42c5e8140494886d5d0c3a8ab84606c9 276 Pfam PF00005 ABC transporter 30 177 5.3E-24 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_663 42c5e8140494886d5d0c3a8ab84606c9 276 SMART SM00382 38 224 3.5E-9 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_274 eb27ed016e04fc926193b0f89b1af1dc 260 Gene3D G3DSA:2.60.40.10 129 216 7.2E-6 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_274 eb27ed016e04fc926193b0f89b1af1dc 260 SUPERFAMILY SSF49299 159 214 7.98E-8 T 18-10-2018 IPR035986 PKD domain superfamily TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 Pfam PF00231 ATP synthase 5 333 1.9E-75 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 280 299 5.6E-20 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 5.6E-20 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 311 332 5.6E-20 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 SUPERFAMILY SSF52943 3 333 6.28E-67 T 18-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 333 29.015 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_425 d06aaf9a3f035f4861369b391a75ad7a 336 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 333 2.7E-74 T 18-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_227 52c94889c3377bad00c0efaf6eb75168 370 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 13 366 2.9E-106 T 18-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_227 52c94889c3377bad00c0efaf6eb75168 370 Pfam PF01098 Cell cycle protein 15 366 5.4E-76 T 18-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_173 bd3cf59ea6cfe68c026798e91b9eb338 404 Pfam PF02687 FtsX-like permease family 300 389 5.5E-7 T 18-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TWT_497 83b2c7eb7d3f96be1c69c72df3f0b5fb 259 SUPERFAMILY SSF52317 18 197 7.56E-12 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_497 83b2c7eb7d3f96be1c69c72df3f0b5fb 259 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 37 186 5.4E-8 T 18-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TWT_473 3e7b1b0de9b4000938d0d01b5415b94d 115 SUPERFAMILY SSF141091 13 111 8.37E-22 T 18-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_473 3e7b1b0de9b4000938d0d01b5415b94d 115 Pfam PF00829 Ribosomal prokaryotic L21 protein 13 111 6.7E-22 T 18-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_473 3e7b1b0de9b4000938d0d01b5415b94d 115 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 12 113 16.673 T 18-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_473 3e7b1b0de9b4000938d0d01b5415b94d 115 TIGRFAM TIGR00061 L21: ribosomal protein bL21 13 111 4.5E-12 T 18-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 Gene3D G3DSA:1.10.8.50 164 289 2.7E-31 T 18-10-2018 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 164 251 6.1E-18 T 18-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 SUPERFAMILY SSF46946 163 248 5.89E-23 T 18-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 SMART SM00898 2 142 1.9E-10 T 18-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 Gene3D G3DSA:3.20.190.10 2 86 4.0E-10 T 18-10-2018 IPR035937 MutM-like, N-terminal TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 SUPERFAMILY SSF57716 258 293 3.99E-8 T 18-10-2018 TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 SUPERFAMILY SSF81624 2 165 1.23E-17 T 18-10-2018 IPR035937 MutM-like, N-terminal TWT_396 e3ccb1c70356eb61dbab8c4b8cb521f0 294 SMART SM01232 164 256 2.9E-20 T 18-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TWT_418 2f40147dd04b2a7dafc4c3a1639a98df 574 Pfam PF05103 DivIVA protein 15 134 8.1E-10 T 18-10-2018 IPR007793 DivIVA family TWT_418 2f40147dd04b2a7dafc4c3a1639a98df 574 SUPERFAMILY SSF58113 63 251 2.09E-5 T 18-10-2018 TWT_029 cce306ca2c054590aceea7825dd61778 287 Gene3D G3DSA:3.40.50.720 6 265 2.6E-91 T 18-10-2018 TWT_029 cce306ca2c054590aceea7825dd61778 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 274 8.8E-83 T 18-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TWT_029 cce306ca2c054590aceea7825dd61778 287 Gene3D G3DSA:3.90.25.10 156 271 2.6E-91 T 18-10-2018 TWT_029 cce306ca2c054590aceea7825dd61778 287 Pfam PF04321 RmlD substrate binding domain 4 275 5.3E-89 T 18-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TWT_029 cce306ca2c054590aceea7825dd61778 287 SUPERFAMILY SSF51735 4 275 2.35E-80 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_342 96089a5d584fd96238812bf18b6547d6 551 Gene3D G3DSA:3.40.50.10490 57 225 3.9E-34 T 18-10-2018 TWT_342 96089a5d584fd96238812bf18b6547d6 551 SUPERFAMILY SSF53697 25 392 3.78E-63 T 18-10-2018 TWT_342 96089a5d584fd96238812bf18b6547d6 551 Gene3D G3DSA:3.40.50.10490 338 398 8.5E-10 T 18-10-2018 TWT_676 93643bf1cee3e132f33e761cb94dd088 156 SUPERFAMILY SSF47973 7 149 2.09E-54 T 18-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TWT_676 93643bf1cee3e132f33e761cb94dd088 156 Gene3D G3DSA:1.10.455.10 2 156 1.6E-55 T 18-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TWT_676 93643bf1cee3e132f33e761cb94dd088 156 Pfam PF00177 Ribosomal protein S7p/S5e 2 149 1.2E-57 T 18-10-2018 IPR023798 Ribosomal protein S7 domain TWT_676 93643bf1cee3e132f33e761cb94dd088 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 18-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_676 93643bf1cee3e132f33e761cb94dd088 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.7E-62 T 18-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TWT_676 93643bf1cee3e132f33e761cb94dd088 156 PIRSF PIRSF002122 6 156 3.2E-55 T 18-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TWT_676 93643bf1cee3e132f33e761cb94dd088 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 33.645 T 18-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TWT_787 b6e607e242addd48794f11b5d0e650c7 196 SUPERFAMILY SSF51283 1 183 4.97E-54 T 18-10-2018 IPR036157 dUTPase-like superfamily TWT_787 b6e607e242addd48794f11b5d0e650c7 196 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 180 2.1E-69 T 18-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TWT_787 b6e607e242addd48794f11b5d0e650c7 196 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 33.057 T 18-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TWT_787 b6e607e242addd48794f11b5d0e650c7 196 Gene3D G3DSA:2.70.40.10 1 186 1.8E-58 T 18-10-2018 IPR036157 dUTPase-like superfamily TWT_787 b6e607e242addd48794f11b5d0e650c7 196 Pfam PF00692 dUTPase 68 180 5.9E-9 T 18-10-2018 IPR029054 dUTPase-like TWT_388 b5c0431950062fb046240d54bf25b712 371 Pfam PF13515 Fusaric acid resistance protein-like 38 160 5.0E-9 T 18-10-2018 TWT_345 ec5c933485bbd1ecb0e87c8c5b229e36 293 Pfam PF13462 Thioredoxin 100 272 1.8E-20 T 18-10-2018 IPR012336 Thioredoxin-like fold TWT_345 ec5c933485bbd1ecb0e87c8c5b229e36 293 Gene3D G3DSA:3.40.30.10 83 289 7.4E-40 T 18-10-2018 TWT_345 ec5c933485bbd1ecb0e87c8c5b229e36 293 SUPERFAMILY SSF52833 96 274 2.76E-22 T 18-10-2018 IPR036249 Thioredoxin-like superfamily TWT_333 4f40d7cea54ffb33e1d58737bfea7c89 116 Pfam PF01883 Iron-sulfur cluster assembly protein 22 81 3.7E-18 T 18-10-2018 IPR002744 MIP18 family-like TWT_333 4f40d7cea54ffb33e1d58737bfea7c89 116 SUPERFAMILY SSF117916 21 110 5.23E-25 T 18-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TWT_333 4f40d7cea54ffb33e1d58737bfea7c89 116 Gene3D G3DSA:3.30.300.130 13 111 9.0E-30 T 18-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TWT_054 38a7466b2cdcfdf865840cee0ce7554d 338 Pfam PF00348 Polyprenyl synthetase 41 262 3.8E-49 T 18-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TWT_054 38a7466b2cdcfdf865840cee0ce7554d 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 18-10-2018 IPR033749 Polyprenyl synthetase, conserved site TWT_054 38a7466b2cdcfdf865840cee0ce7554d 338 SUPERFAMILY SSF48576 13 337 8.64E-73 T 18-10-2018 IPR008949 Isoprenoid synthase domain superfamily TWT_054 38a7466b2cdcfdf865840cee0ce7554d 338 Gene3D G3DSA:1.10.600.10 11 337 1.2E-82 T 18-10-2018 IPR008949 Isoprenoid synthase domain superfamily TWT_726 ed2173a8b201df25be67537cf9235d46 417 SUPERFAMILY SSF46589 2 111 8.37E-17 T 18-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PIRSF PIRSF001529 1 417 1.3E-132 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 1.3E-27 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 1.3E-27 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 1.3E-27 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 1.3E-27 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 1.3E-27 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 37.557 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 Gene3D G3DSA:1.10.287.40 1 103 1.2E-12 T 18-10-2018 TWT_726 ed2173a8b201df25be67537cf9235d46 417 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 408 2.8E-126 T 18-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TWT_726 ed2173a8b201df25be67537cf9235d46 417 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 393 1.1E-27 T 18-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_726 ed2173a8b201df25be67537cf9235d46 417 SUPERFAMILY SSF55681 112 415 2.55E-85 T 18-10-2018 TWT_726 ed2173a8b201df25be67537cf9235d46 417 Gene3D G3DSA:3.30.930.10 104 417 2.4E-112 T 18-10-2018 TWT_726 ed2173a8b201df25be67537cf9235d46 417 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 2.5E-15 T 18-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 423 47.12 T 18-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 18-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 PIRSF PIRSF000412 4 424 1.3E-143 T 18-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 SUPERFAMILY SSF53383 6 422 1.39E-156 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 Gene3D G3DSA:3.40.640.10 43 293 1.3E-158 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 Pfam PF00464 Serine hydroxymethyltransferase 15 396 2.7E-145 T 18-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TWT_635 71248f2f8ecec6354df7904fb6b5b0df 428 Gene3D G3DSA:3.90.1150.10 17 401 1.3E-158 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_669 81941ba3c1cec33e83f5ea76d7482d20 1172 SUPERFAMILY SSF52540 245 1047 2.69E-10 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_669 81941ba3c1cec33e83f5ea76d7482d20 1172 Gene3D G3DSA:3.40.50.300 877 1058 2.5E-5 T 18-10-2018 TWT_097 b57e4dd0ab9e3b93006be719edaa302e 349 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 30 104 6.1E-11 T 18-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TWT_097 b57e4dd0ab9e3b93006be719edaa302e 349 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 20 348 51.695 T 18-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TWT_097 b57e4dd0ab9e3b93006be719edaa302e 349 Gene3D G3DSA:1.10.150.130 22 123 4.7E-18 T 18-10-2018 IPR010998 Integrase/recombinase, N-terminal TWT_097 b57e4dd0ab9e3b93006be719edaa302e 349 Pfam PF00589 Phage integrase family 129 333 1.5E-42 T 18-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TWT_097 b57e4dd0ab9e3b93006be719edaa302e 349 SUPERFAMILY SSF56349 30 340 1.94E-51 T 18-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TWT_590 426168e19461159796c5303d4e98e874 415 SUPERFAMILY SSF52402 31 321 3.64E-46 T 18-10-2018 TWT_590 426168e19461159796c5303d4e98e874 415 SUPERFAMILY SSF82829 299 406 3.4E-12 T 18-10-2018 TWT_590 426168e19461159796c5303d4e98e874 415 Pfam PF01171 PP-loop family 244 288 4.0E-7 T 18-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TWT_590 426168e19461159796c5303d4e98e874 415 Pfam PF01171 PP-loop family 31 162 2.4E-25 T 18-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TWT_590 426168e19461159796c5303d4e98e874 415 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 15 400 21.5 T 18-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TWT_590 426168e19461159796c5303d4e98e874 415 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 31 164 2.5E-27 T 18-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TWT_582 d55a93d788df26771572f5e60e04c318 230 SUPERFAMILY SSF52141 12 229 1.59E-69 T 18-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 16 219 4.2E-57 T 18-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 Pfam PF03167 Uracil DNA glycosylase superfamily 58 220 1.6E-16 T 18-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 Gene3D G3DSA:3.40.470.10 4 230 2.2E-78 T 18-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 SMART SM00986 56 217 2.0E-27 T 18-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 SMART SM00987 56 217 2.0E-27 T 18-10-2018 TWT_582 d55a93d788df26771572f5e60e04c318 230 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 14 228 32.23 T 18-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_582 d55a93d788df26771572f5e60e04c318 230 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 64 73 - T 18-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TWT_036 2228b89277e2003bb56ab0d28f15d1e0 323 Gene3D G3DSA:3.90.550.10 2 252 8.9E-45 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_036 2228b89277e2003bb56ab0d28f15d1e0 323 SUPERFAMILY SSF53448 3 226 4.5E-45 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_036 2228b89277e2003bb56ab0d28f15d1e0 323 Pfam PF00535 Glycosyl transferase family 2 4 134 1.7E-24 T 18-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TWT_650 7c2c62fc31fed3075888c73b9b253233 330 PIRSF PIRSF016839 5 330 4.5E-108 T 18-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 TWT_650 7c2c62fc31fed3075888c73b9b253233 330 Pfam PF02126 Phosphotriesterase family 15 327 7.7E-44 T 18-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 TWT_650 7c2c62fc31fed3075888c73b9b253233 330 Gene3D G3DSA:3.20.20.140 5 330 3.4E-86 T 18-10-2018 TWT_650 7c2c62fc31fed3075888c73b9b253233 330 SUPERFAMILY SSF51556 6 327 9.95E-75 T 18-10-2018 IPR032466 Metal-dependent hydrolase TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 Gene3D G3DSA:2.40.240.10 25 114 5.9E-20 T 18-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 SUPERFAMILY SSF50715 26 203 2.27E-39 T 18-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 Pfam PF01386 Ribosomal L25p family 28 111 5.9E-18 T 18-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 27 114 2.0E-31 T 18-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 25 199 22.705 T 18-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 Gene3D G3DSA:2.170.120.20 116 204 1.6E-13 T 18-10-2018 IPR037121 Ribosomal protein L25, C-terminal TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 28 195 2.4E-34 T 18-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TWT_654 9a2a37afd5a09a3525c3dc3d744d3570 208 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 120 197 1.5E-15 T 18-10-2018 IPR020057 Ribosomal protein L25, beta domain TWT_490 732ad36d6aba8897b3c8e7ebb45f4114 320 Pfam PF11268 Protein of unknown function (DUF3071) 14 169 3.7E-30 T 18-10-2018 IPR021421 Protein of unknown function DUF3071 TWT_317 6ec718005a1800741d5b3cc7fa30c8ba 307 Pfam PF09754 PAC2 family 26 246 9.6E-35 T 18-10-2018 IPR019151 Proteasome assembly chaperone 2 TWT_317 6ec718005a1800741d5b3cc7fa30c8ba 307 Gene3D G3DSA:1.10.287.100 228 267 1.9E-67 T 18-10-2018 TWT_317 6ec718005a1800741d5b3cc7fa30c8ba 307 PIRSF PIRSF028754 11 297 6.0E-58 T 18-10-2018 IPR008492 Protein of unknown function DUF774 TWT_317 6ec718005a1800741d5b3cc7fa30c8ba 307 Gene3D G3DSA:3.40.50.10900 19 227 1.9E-67 T 18-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TWT_317 6ec718005a1800741d5b3cc7fa30c8ba 307 SUPERFAMILY SSF159659 16 268 5.23E-62 T 18-10-2018 TWT_466 7f9eed8c781c2c3df2e10efccb52cd10 350 Gene3D G3DSA:3.60.10.10 128 350 1.5E-20 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_466 7f9eed8c781c2c3df2e10efccb52cd10 350 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 135 339 4.2E-13 T 18-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TWT_466 7f9eed8c781c2c3df2e10efccb52cd10 350 SUPERFAMILY SSF56219 128 346 9.68E-21 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_018 0e73f2f848211dad5d5f6976f83aa20a 294 PIRSF PIRSF000477 19 286 3.0E-75 T 18-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TWT_018 0e73f2f848211dad5d5f6976f83aa20a 294 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 46 283 7.7E-64 T 18-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TWT_018 0e73f2f848211dad5d5f6976f83aa20a 294 Gene3D G3DSA:3.40.50.1580 17 285 5.9E-77 T 18-10-2018 TWT_018 0e73f2f848211dad5d5f6976f83aa20a 294 SUPERFAMILY SSF53167 31 285 3.76E-72 T 18-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TWT_018 0e73f2f848211dad5d5f6976f83aa20a 294 Pfam PF01048 Phosphorylase superfamily 46 284 8.5E-39 T 18-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 Gene3D G3DSA:3.20.20.70 147 307 1.6E-105 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 SUPERFAMILY SSF54675 5 133 2.35E-39 T 18-10-2018 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 423 7.5E-116 T 18-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 Gene3D G3DSA:3.20.140.10 6 419 1.6E-105 T 18-10-2018 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 PIRSF PIRSF000484 3 431 5.6E-93 T 18-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TWT_623 fecd947f1f30cb41b02569f6e6b28faa 442 SUPERFAMILY SSF51690 135 422 5.0E-72 T 18-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TWT_239 7ef9657a7a6ade9dd630946b83c21ab3 161 Hamap MF_00042 Ribonuclease H [rnhA]. 3 149 25.867 T 18-10-2018 IPR022892 Ribonuclease HI GO:0004523 TWT_239 7ef9657a7a6ade9dd630946b83c21ab3 161 SUPERFAMILY SSF53098 5 143 2.53E-41 T 18-10-2018 IPR012337 Ribonuclease H-like superfamily TWT_239 7ef9657a7a6ade9dd630946b83c21ab3 161 Pfam PF00075 RNase H 5 140 1.4E-34 T 18-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TWT_239 7ef9657a7a6ade9dd630946b83c21ab3 161 Gene3D G3DSA:3.30.420.10 1 150 7.3E-47 T 18-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TWT_793 44d220485edf7ecf717dbdda98f1b90f 105 Gene3D G3DSA:1.20.59.10 7 105 1.6E-23 T 18-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TWT_793 44d220485edf7ecf717dbdda98f1b90f 105 SUPERFAMILY SSF48600 20 103 1.83E-19 T 18-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TWT_793 44d220485edf7ecf717dbdda98f1b90f 105 Pfam PF01817 Chorismate mutase type II 25 102 1.7E-14 T 18-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TWT_793 44d220485edf7ecf717dbdda98f1b90f 105 SMART SM00830 25 105 8.3E-21 T 18-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 Pfam PF01883 Iron-sulfur cluster assembly protein 24 90 6.3E-14 T 18-10-2018 IPR002744 MIP18 family-like TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 SUPERFAMILY SSF52540 122 384 5.59E-41 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 SUPERFAMILY SSF117916 19 111 1.18E-17 T 18-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 123 383 3.4E-70 T 18-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 Hamap MF_02040 Iron-sulfur cluster carrier protein. 116 388 30.726 T 18-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 Gene3D G3DSA:3.30.300.130 17 112 5.0E-16 T 18-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TWT_525 d0f9efa54a2f1832f360e537c521e6f6 389 Gene3D G3DSA:3.40.50.300 114 373 3.2E-61 T 18-10-2018 TWT_758 c65ff176678565e03b6e62a615e08f58 541 Pfam PF05140 ResB-like family 15 511 4.2E-108 T 18-10-2018 IPR007816 ResB-like domain TWT_765 6defec35ca929790067e3d5556970a16 267 SUPERFAMILY SSF53448 10 220 3.94E-39 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_765 6defec35ca929790067e3d5556970a16 267 Pfam PF00535 Glycosyl transferase family 2 10 172 2.7E-27 T 18-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TWT_765 6defec35ca929790067e3d5556970a16 267 Gene3D G3DSA:3.90.550.10 8 240 2.0E-42 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 SUPERFAMILY SSF52021 6 141 4.45E-47 T 18-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 Pfam PF00117 Glutamine amidotransferase class-I 183 367 4.3E-34 T 18-10-2018 IPR017926 Glutamine amidotransferase TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 373 40.768 T 18-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 134 4.7E-43 T 18-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 Gene3D G3DSA:3.40.50.880 181 371 1.8E-26 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 Gene3D G3DSA:3.50.30.20 4 152 1.2E-47 T 18-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 SUPERFAMILY SSF52317 157 372 1.03E-46 T 18-10-2018 IPR029062 Class I glutamine amidotransferase-like TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 370 9.7E-120 T 18-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 268 285 1.6E-29 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 267 1.6E-29 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 181 195 1.6E-29 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 293 304 1.6E-29 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 220 234 1.6E-29 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00097 Anthranilate synthase component II signature 223 232 2.3E-5 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00097 Anthranilate synthase component II signature 344 357 2.3E-5 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00097 Anthranilate synthase component II signature 251 262 2.3E-5 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 SMART SM01097 5 135 6.2E-71 T 18-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 344 357 2.7E-10 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 223 232 2.7E-10 T 18-10-2018 TWT_366 cf0c373dd82df5d38a932bfa5888a092 381 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 262 2.7E-10 T 18-10-2018 TWT_683 a410a85745767bce42eb2a2d22a39995 792 Gene3D G3DSA:3.20.70.20 75 766 5.2E-213 T 18-10-2018 TWT_683 a410a85745767bce42eb2a2d22a39995 792 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 622 - T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 755 1.0E-168 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 508 530 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 536 559 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 611 638 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 493 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 1.2E-39 T 18-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 SUPERFAMILY SSF51998 222 760 1.25E-159 T 18-10-2018 TWT_683 a410a85745767bce42eb2a2d22a39995 792 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 148 759 7.0E-203 T 18-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 145 219 2.0E-13 T 18-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 Pfam PF03477 ATP cone domain 4 87 2.5E-10 T 18-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TWT_683 a410a85745767bce42eb2a2d22a39995 792 SUPERFAMILY SSF48168 8 221 7.85E-48 T 18-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TWT_667 7f201d18f99cf7aa8d7e5d8242229dfb 203 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 42 184 2.5E-28 T 18-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TWT_667 7f201d18f99cf7aa8d7e5d8242229dfb 203 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 36 184 1.1E-37 T 18-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TWT_667 7f201d18f99cf7aa8d7e5d8242229dfb 203 PIRSF PIRSF006806 1 187 8.2E-34 T 18-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TWT_667 7f201d18f99cf7aa8d7e5d8242229dfb 203 Gene3D G3DSA:3.40.50.10420 2 200 9.9E-38 T 18-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TWT_667 7f201d18f99cf7aa8d7e5d8242229dfb 203 SUPERFAMILY SSF100950 3 196 5.72E-42 T 18-10-2018 IPR037171 NagB/RpiA transferase-like TWT_126 539618ace15d95804642ca960cd28d36 110 Pfam PF12005 Protein of unknown function (DUF3499) 44 105 1.3E-15 T 18-10-2018 IPR021888 Protein of unknown function DUF3499 TWT_215 493b208e0727db8c8e14d5b1030009a1 472 Pfam PF01474 Class-II DAHP synthetase family 39 468 1.1E-189 T 18-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TWT_215 493b208e0727db8c8e14d5b1030009a1 472 SUPERFAMILY SSF51569 29 472 4.61E-185 T 18-10-2018 TWT_215 493b208e0727db8c8e14d5b1030009a1 472 Gene3D G3DSA:3.20.20.70 70 212 4.5E-48 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_215 493b208e0727db8c8e14d5b1030009a1 472 Gene3D G3DSA:3.20.20.70 213 472 1.1E-101 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_215 493b208e0727db8c8e14d5b1030009a1 472 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 38 471 2.5E-195 T 18-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TWT_112 9ccaaa948700ead041e6f4c226928d91 226 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 66 134 5.2E-25 T 18-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TWT_112 9ccaaa948700ead041e6f4c226928d91 226 SMART SM00529 27 126 4.0E-33 T 18-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TWT_112 9ccaaa948700ead041e6f4c226928d91 226 SUPERFAMILY SSF46785 5 63 9.49E-9 T 18-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TWT_112 9ccaaa948700ead041e6f4c226928d91 226 SUPERFAMILY SSF50037 132 225 3.85E-16 T 18-10-2018 IPR008988 Transcriptional repressor, C-terminal TWT_112 9ccaaa948700ead041e6f4c226928d91 226 SUPERFAMILY SSF47979 66 138 2.88E-23 T 18-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TWT_112 9ccaaa948700ead041e6f4c226928d91 226 Gene3D G3DSA:1.10.10.10 1 138 2.1E-43 T 18-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TWT_112 9ccaaa948700ead041e6f4c226928d91 226 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 61 3.9E-12 T 18-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TWT_115 1d643c741e3fd9c3895ce20701048b07 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 4.8E-24 T 18-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_115 1d643c741e3fd9c3895ce20701048b07 101 SUPERFAMILY SSF57716 3 101 4.42E-32 T 18-10-2018 TWT_115 1d643c741e3fd9c3895ce20701048b07 101 Gene3D G3DSA:4.10.830.10 41 101 1.5E-22 T 18-10-2018 TWT_115 1d643c741e3fd9c3895ce20701048b07 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.13 T 18-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid TWT_349 ad3f72cca1fbc05bc0f50b5899dc35ac 160 SUPERFAMILY SSF141259 2 66 6.15E-12 T 18-10-2018 IPR036101 CarD-like/TRCF domain superfamily TWT_349 ad3f72cca1fbc05bc0f50b5899dc35ac 160 Gene3D G3DSA:2.30.30.840 1 60 2.7E-20 T 18-10-2018 TWT_349 ad3f72cca1fbc05bc0f50b5899dc35ac 160 Gene3D G3DSA:1.20.58.1290 61 160 1.1E-32 T 18-10-2018 TWT_349 ad3f72cca1fbc05bc0f50b5899dc35ac 160 Pfam PF02559 CarD-like/TRCF domain 3 111 4.5E-14 T 18-10-2018 IPR003711 CarD-like/TRCF domain TWT_349 ad3f72cca1fbc05bc0f50b5899dc35ac 160 SMART SM01058 2 112 1.7E-27 T 18-10-2018 IPR003711 CarD-like/TRCF domain TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 SMART SM00983 128 203 3.3E-14 T 18-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 10 205 1.6E-55 T 18-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 SUPERFAMILY SSF63862 143 205 1.1E-6 T 18-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 147 202 7.5E-7 T 18-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 28 125 2.0E-15 T 18-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 SUPERFAMILY SSF63999 9 128 5.1E-26 T 18-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_008 fcc8fbfb7bdc8583a0524a924423b953 233 Gene3D G3DSA:3.40.50.10240 12 215 6.4E-47 T 18-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TWT_230 9fa8fa4910649d233dab3a35617bbad1 249 Pfam PF08478 POTRA domain, FtsQ-type 57 124 4.3E-14 T 18-10-2018 IPR013685 POTRA domain, FtsQ-type TWT_391 aed819376d720f7d0337927084bfced8 132 Pfam PF02657 Fe-S metabolism associated domain 17 130 3.5E-20 T 18-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like TWT_391 aed819376d720f7d0337927084bfced8 132 SUPERFAMILY SSF82649 2 131 7.32E-24 T 18-10-2018 TWT_391 aed819376d720f7d0337927084bfced8 132 Gene3D G3DSA:3.90.1010.10 1 132 3.0E-38 T 18-10-2018 TWT_373 8e3ccc16f77893af01cdb30787cfa4cf 315 SUPERFAMILY SSF51735 153 293 6.02E-12 T 18-10-2018 IPR036291 NAD(P)-binding domain superfamily TWT_373 8e3ccc16f77893af01cdb30787cfa4cf 315 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 3.4E-22 T 18-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TWT_373 8e3ccc16f77893af01cdb30787cfa4cf 315 Gene3D G3DSA:3.40.50.10860 3 121 2.4E-26 T 18-10-2018 TWT_373 8e3ccc16f77893af01cdb30787cfa4cf 315 Gene3D G3DSA:3.40.50.720 151 304 4.8E-18 T 18-10-2018 TWT_373 8e3ccc16f77893af01cdb30787cfa4cf 315 SUPERFAMILY SSF53223 4 93 3.86E-23 T 18-10-2018 TWT_681 004cb9ac42798749daab3a59e80119fc 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 46 59 - T 18-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TWT_681 004cb9ac42798749daab3a59e80119fc 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 322 6.9E-73 T 18-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TWT_681 004cb9ac42798749daab3a59e80119fc 427 SUPERFAMILY SSF53686 17 330 6.42E-85 T 18-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TWT_681 004cb9ac42798749daab3a59e80119fc 427 SUPERFAMILY SSF55021 342 424 1.47E-5 T 18-10-2018 TWT_681 004cb9ac42798749daab3a59e80119fc 427 Gene3D G3DSA:3.40.50.1100 56 146 1.6E-101 T 18-10-2018 TWT_681 004cb9ac42798749daab3a59e80119fc 427 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 25 423 7.0E-116 T 18-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 TWT_681 004cb9ac42798749daab3a59e80119fc 427 Gene3D G3DSA:3.40.50.1100 24 327 1.6E-101 T 18-10-2018 TWT_722 f98fc1de9df8492a998f6c6abfb0ea7b 41 Pfam PF11273 Protein of unknown function (DUF3073) 2 40 4.1E-16 T 18-10-2018 IPR021426 Protein of unknown function DUF3073 TWT_776 be67199149af9b25118379096e4a4891 485 SUPERFAMILY SSF56601 150 483 4.48E-84 T 18-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TWT_776 be67199149af9b25118379096e4a4891 485 SUPERFAMILY SSF56519 89 131 4.32E-6 T 18-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TWT_776 be67199149af9b25118379096e4a4891 485 Gene3D G3DSA:3.90.1310.10 77 385 3.8E-117 T 18-10-2018 TWT_776 be67199149af9b25118379096e4a4891 485 Gene3D G3DSA:3.40.710.10 149 477 3.8E-117 T 18-10-2018 TWT_776 be67199149af9b25118379096e4a4891 485 Pfam PF00905 Penicillin binding protein transpeptidase domain 167 479 3.3E-63 T 18-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TWT_541 ef361454a69bffacb37747c462476cdd 132 Gene3D G3DSA:3.30.1370.30 2 72 1.3E-25 T 18-10-2018 TWT_541 ef361454a69bffacb37747c462476cdd 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 29.944 T 18-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_541 ef361454a69bffacb37747c462476cdd 132 Pfam PF00410 Ribosomal protein S8 5 132 6.0E-45 T 18-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_541 ef361454a69bffacb37747c462476cdd 132 Gene3D G3DSA:3.30.1490.10 75 132 8.2E-23 T 18-10-2018 TWT_541 ef361454a69bffacb37747c462476cdd 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 18-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_541 ef361454a69bffacb37747c462476cdd 132 SUPERFAMILY SSF56047 3 132 1.7E-43 T 18-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 PRINTS PR00059 Ribosomal protein L6 signature 119 135 7.6E-29 T 18-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 PRINTS PR00059 Ribosomal protein L6 signature 91 116 7.6E-29 T 18-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 PRINTS PR00059 Ribosomal protein L6 signature 161 182 7.6E-29 T 18-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 21 196 35.464 T 18-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 174 182 - T 18-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 Gene3D G3DSA:3.90.930.12 21 102 1.8E-26 T 18-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 SUPERFAMILY SSF56053 21 102 3.12E-22 T 18-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 22 196 4.0E-67 T 18-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 PIRSF PIRSF002162 20 197 3.6E-43 T 18-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 Gene3D G3DSA:3.90.930.12 103 198 5.7E-36 T 18-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 SUPERFAMILY SSF56053 103 196 1.27E-32 T 18-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 Pfam PF00347 Ribosomal protein L6 110 184 1.1E-15 T 18-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_540 d0c6fc3178fc9c8fe3ea17c6b8850f51 198 Pfam PF00347 Ribosomal protein L6 31 102 1.3E-14 T 18-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TWT_443 be7453a69af121b88e61ad97f81c7ffc 180 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 39 71 4.1E-11 T 18-10-2018 IPR019933 DivIVA domain TWT_443 be7453a69af121b88e61ad97f81c7ffc 180 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 141 170 7.3E-10 T 18-10-2018 IPR019933 DivIVA domain TWT_443 be7453a69af121b88e61ad97f81c7ffc 180 TIGRFAM TIGR03543 divI1A_rptt_fam: DivIVA domain repeat protein 6 178 1.0E-74 T 18-10-2018 IPR019932 Conserved hypothetical protein CHP03543 TWT_658 0b6112b3a8f32e9ebe8b5f6c0a36e640 184 Pfam PF07884 Vitamin K epoxide reductase family 14 145 3.0E-25 T 18-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TWT_658 0b6112b3a8f32e9ebe8b5f6c0a36e640 184 Gene3D G3DSA:1.20.1440.130 5 160 2.8E-15 T 18-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 TWT_658 0b6112b3a8f32e9ebe8b5f6c0a36e640 184 SMART SM00756 8 150 2.2E-46 T 18-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TWT_602 5a50453732b683d0050c58c5a8292946 804 Pfam PF07861 WisP family N-Terminal Region 45 283 7.4E-161 T 18-10-2018 IPR012503 WisP, N-terminal TWT_602 5a50453732b683d0050c58c5a8292946 804 Pfam PF05345 Putative Ig domain 407 444 8.6E-13 T 18-10-2018 IPR008009 Putative Ig TWT_602 5a50453732b683d0050c58c5a8292946 804 Pfam PF05345 Putative Ig domain 735 782 1.4E-7 T 18-10-2018 IPR008009 Putative Ig TWT_602 5a50453732b683d0050c58c5a8292946 804 Pfam PF05345 Putative Ig domain 646 690 7.0E-8 T 18-10-2018 IPR008009 Putative Ig TWT_410 0121e9bfbc1a305aa2c4ed8fc6feec28 318 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 121 308 1.2E-5 T 18-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TWT_410 0121e9bfbc1a305aa2c4ed8fc6feec28 318 SUPERFAMILY SSF56219 114 314 1.58E-13 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_410 0121e9bfbc1a305aa2c4ed8fc6feec28 318 Gene3D G3DSA:3.60.10.10 90 317 1.5E-9 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_010 079c262be4bd8e2b9332c85358ad2269 69 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 69 21.761 T 18-10-2018 IPR009619 Cell division protein CrgA TWT_010 079c262be4bd8e2b9332c85358ad2269 69 Pfam PF06781 Cell division protein CrgA 3 69 1.9E-20 T 18-10-2018 IPR009619 Cell division protein CrgA TWT_149 f2b8337a2e8ab715496eb37fe9627798 410 SUPERFAMILY SSF54001 283 401 6.38E-32 T 18-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TWT_149 f2b8337a2e8ab715496eb37fe9627798 410 Gene3D G3DSA:3.90.1720.10 172 405 2.9E-40 T 18-10-2018 TWT_149 f2b8337a2e8ab715496eb37fe9627798 410 Pfam PF00877 NlpC/P60 family 303 402 6.7E-18 T 18-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TWT_190 c4a485a2c46237e53d43342b4e77bfa9 294 Pfam PF00482 Type II secretion system (T2SS), protein F 123 247 2.3E-9 T 18-10-2018 IPR018076 Type II secretion system F domain TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 9.4E-21 T 18-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 9.4E-21 T 18-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 330 345 9.4E-21 T 18-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 422 433 9.4E-21 T 18-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Gene3D G3DSA:3.40.50.620 300 410 3.2E-37 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 SUPERFAMILY SSF47323 423 580 6.17E-31 T 18-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Pfam PF09334 tRNA synthetases class I (M) 316 434 9.5E-37 T 18-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Pfam PF09334 tRNA synthetases class I (M) 3 263 1.7E-63 T 18-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Pfam PF08264 Anticodon-binding domain of tRNA 460 550 8.4E-7 T 18-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Gene3D G3DSA:1.10.730.10 412 582 1.9E-36 T 18-10-2018 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 SUPERFAMILY SSF52374 3 424 3.55E-99 T 18-10-2018 TWT_763 2d7ef473af8d04ce984aa4c3c4a89b93 583 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 580 41.122 T 18-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TWT_389 1137430cfd75c0324dfbcdcaaf493de7 402 SUPERFAMILY SSF53955 328 395 3.26E-6 T 18-10-2018 IPR023346 Lysozyme-like domain superfamily TWT_616 dff2a93dc0d096115cb01b9d0879fdce 244 SUPERFAMILY SSF69796 10 237 9.68E-55 T 18-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TWT_616 dff2a93dc0d096115cb01b9d0879fdce 244 Gene3D G3DSA:3.30.1360.170 12 244 1.9E-65 T 18-10-2018 TWT_616 dff2a93dc0d096115cb01b9d0879fdce 244 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 19 236 2.9E-54 T 18-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TWT_616 dff2a93dc0d096115cb01b9d0879fdce 244 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 9 244 27.918 T 18-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TWT_616 dff2a93dc0d096115cb01b9d0879fdce 244 Pfam PF02511 Thymidylate synthase complementing protein 20 231 7.3E-50 T 18-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 Gene3D G3DSA:3.40.250.10 16 164 1.2E-36 T 18-10-2018 IPR036873 Rhodanese-like domain superfamily TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 SMART SM00450 166 294 1.1E-16 T 18-10-2018 IPR001763 Rhodanese-like domain TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 SMART SM00450 30 144 9.8E-12 T 18-10-2018 IPR001763 Rhodanese-like domain TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 SUPERFAMILY SSF52821 25 162 3.54E-33 T 18-10-2018 IPR036873 Rhodanese-like domain superfamily TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 Pfam PF00581 Rhodanese-like domain 172 289 2.4E-15 T 18-10-2018 IPR001763 Rhodanese-like domain TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 Pfam PF00581 Rhodanese-like domain 34 140 1.4E-12 T 18-10-2018 IPR001763 Rhodanese-like domain TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 Gene3D G3DSA:3.40.250.10 165 302 8.7E-39 T 18-10-2018 IPR036873 Rhodanese-like domain superfamily TWT_390 ef3bf607be60fcde6b8ae78dec5ad030 302 SUPERFAMILY SSF52821 172 299 4.58E-30 T 18-10-2018 IPR036873 Rhodanese-like domain superfamily TWT_357 2ef1f60f59ad97749f68325fb7382cfc 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 196 4.0E-60 T 18-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TWT_357 2ef1f60f59ad97749f68325fb7382cfc 219 SUPERFAMILY SSF51366 1 212 1.8E-53 T 18-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TWT_357 2ef1f60f59ad97749f68325fb7382cfc 219 Gene3D G3DSA:3.20.20.70 1 217 1.7E-71 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_357 2ef1f60f59ad97749f68325fb7382cfc 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 18-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TWT_357 2ef1f60f59ad97749f68325fb7382cfc 219 PIRSF PIRSF001461 1 218 8.0E-73 T 18-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TWT_033 0692381b697047d72743e51f8f9fb2de 282 SUPERFAMILY SSF53448 9 265 3.72E-42 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_033 0692381b697047d72743e51f8f9fb2de 282 Pfam PF00535 Glycosyl transferase family 2 10 192 1.1E-20 T 18-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TWT_033 0692381b697047d72743e51f8f9fb2de 282 Gene3D G3DSA:3.90.550.10 3 238 1.1E-40 T 18-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Pfam PF13522 Glutamine amidotransferase domain 68 187 3.5E-21 T 18-10-2018 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Gene3D G3DSA:3.40.50.10490 252 615 3.1E-131 T 18-10-2018 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Gene3D G3DSA:3.40.50.10490 450 601 3.1E-131 T 18-10-2018 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 SUPERFAMILY SSF53697 251 616 8.72E-97 T 18-10-2018 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Pfam PF01380 SIS domain 466 597 9.4E-22 T 18-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Pfam PF01380 SIS domain 297 420 8.4E-27 T 18-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 616 38.027 T 18-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 SUPERFAMILY SSF56235 2 239 6.18E-68 T 18-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 616 2.3E-226 T 18-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TWT_606 74648823afc14e49780a43fdb4a6dd0a 616 Gene3D G3DSA:3.60.20.10 2 244 1.6E-73 T 18-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TWT_070 e51d19013969969465bc249a87710211 303 Pfam PF01040 UbiA prenyltransferase family 37 273 4.8E-29 T 18-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TWT_070 e51d19013969969465bc249a87710211 303 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 14 301 18.002 T 18-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TWT_070 e51d19013969969465bc249a87710211 303 PIRSF PIRSF005355 6 303 3.3E-85 T 18-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 TWT_070 e51d19013969969465bc249a87710211 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 23 278 6.7E-46 T 18-10-2018 TWT_427 47860d3292c8f139aee659a8f30caf56 327 Pfam PF00213 ATP synthase delta (OSCP) subunit 170 317 7.8E-19 T 18-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_427 47860d3292c8f139aee659a8f30caf56 327 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 282 301 - T 18-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_427 47860d3292c8f139aee659a8f30caf56 327 Hamap MF_01416 ATP synthase subunit delta [atpD]. 96 322 10.689 T 18-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TWT_319 9564f86d56abb5ed09f1c0df0f006284 294 SUPERFAMILY SSF54534 187 284 1.22E-32 T 18-10-2018 TWT_319 9564f86d56abb5ed09f1c0df0f006284 294 Gene3D G3DSA:3.10.50.40 178 294 8.8E-31 T 18-10-2018 TWT_319 9564f86d56abb5ed09f1c0df0f006284 294 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 203 284 2.9E-19 T 18-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TWT_304 1a9df2fecda0e3101a78ba859c84264c 133 Pfam PF13397 RNA polymerase-binding protein 32 128 1.1E-23 T 18-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TWT_304 1a9df2fecda0e3101a78ba859c84264c 133 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 34 133 16.724 T 18-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TWT_213 fd9ee4430eea3146089d178217506605 314 SUPERFAMILY SSF53067 13 310 7.6E-55 T 18-10-2018 TWT_213 fd9ee4430eea3146089d178217506605 314 Gene3D G3DSA:3.30.420.40 133 292 4.3E-84 T 18-10-2018 TWT_213 fd9ee4430eea3146089d178217506605 314 Gene3D G3DSA:3.30.420.40 14 305 4.3E-84 T 18-10-2018 TWT_213 fd9ee4430eea3146089d178217506605 314 Pfam PF00480 ROK family 14 309 1.1E-70 T 18-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TWT_702 3e383ecb966826c966e3b667bc9d1ff5 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 150 2.8E-27 T 18-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TWT_702 3e383ecb966826c966e3b667bc9d1ff5 152 SUPERFAMILY SSF55298 1 149 2.67E-46 T 18-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TWT_702 3e383ecb966826c966e3b667bc9d1ff5 152 Gene3D G3DSA:3.30.1330.40 1 151 8.2E-52 T 18-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 SUPERFAMILY SSF52096 36 302 5.55E-73 T 18-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 142 162 - T 18-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 Gene3D G3DSA:3.90.226.10 19 244 6.0E-71 T 18-10-2018 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 Pfam PF00378 Enoyl-CoA hydratase/isomerase 44 299 1.1E-55 T 18-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 TIGRFAM TIGR01929 menB: naphthoate synthase 37 301 3.1E-113 T 18-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 27 304 49.437 T 18-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TWT_110 52637ebcf774a9f9d1f3faa5459826be 305 Gene3D G3DSA:1.10.12.10 245 293 3.8E-25 T 18-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TWT_063 b3df8b56216ae9346e43136e868942d6 288 Hamap MF_00158 Pantothenate synthetase [panC]. 4 285 29.733 T 18-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TWT_063 b3df8b56216ae9346e43136e868942d6 288 SUPERFAMILY SSF52374 8 285 4.22E-69 T 18-10-2018 TWT_063 b3df8b56216ae9346e43136e868942d6 288 Gene3D G3DSA:3.30.1300.10 177 287 1.3E-7 T 18-10-2018 TWT_063 b3df8b56216ae9346e43136e868942d6 288 Gene3D G3DSA:3.40.50.620 3 170 1.1E-57 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_063 b3df8b56216ae9346e43136e868942d6 288 Pfam PF02569 Pantoate-beta-alanine ligase 17 283 9.7E-68 T 18-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TWT_728 d51b1345227bb5518f648ad25d81f3ca 387 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 86 241 2.9E-35 T 18-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TWT_728 d51b1345227bb5518f648ad25d81f3ca 387 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 241 5.5E-33 T 18-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TWT_728 d51b1345227bb5518f648ad25d81f3ca 387 Gene3D G3DSA:1.10.260.150 52 323 5.1E-56 T 18-10-2018 TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 SUPERFAMILY SSF53474 20 238 8.65E-26 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 Gene3D G3DSA:3.40.50.1820 253 451 1.1E-34 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 Pfam PF02230 Phospholipase/Carboxylesterase 23 235 4.3E-13 T 18-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 Pfam PF02230 Phospholipase/Carboxylesterase 260 452 3.9E-12 T 18-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 Gene3D G3DSA:3.40.50.1820 18 239 6.8E-30 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_073 972926c0065b04a47c8cf637d4a9bdde 453 SUPERFAMILY SSF53474 259 452 1.76E-27 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 SUPERFAMILY SSF53383 24 429 1.89E-119 T 18-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 Gene3D G3DSA:3.40.640.10 70 331 1.2E-140 T 18-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 PIRSF PIRSF000521 134 431 1.3E-35 T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 PIRSF PIRSF000521 1 139 1.6E-10 T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 Gene3D G3DSA:3.90.1150.10 12 424 1.2E-140 T 18-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TWT_633 daa8e02f0cce5bd5bda5ebc0a8c368b1 432 Pfam PF00202 Aminotransferase class-III 28 428 8.5E-114 T 18-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 146 255 1.3E-21 T 18-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 133 245 2.1E-26 T 18-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 Gene3D G3DSA:3.90.470.20 1 115 9.1E-19 T 18-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 114 3.1E-15 T 18-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 Gene3D G3DSA:3.40.50.300 124 266 1.4E-28 T 18-10-2018 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 6 114 1.0E-9 T 18-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 109 1.1E-9 T 18-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 SUPERFAMILY SSF56214 2 114 1.33E-14 T 18-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TWT_593 cb2dbe95f15bab755e53c2e26a02be9b 280 SUPERFAMILY SSF52540 145 256 1.37E-16 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_405 1ddf5e03ba540774ba5f7b5fc2214877 291 Gene3D G3DSA:3.40.50.620 18 291 1.1E-74 T 18-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TWT_405 1ddf5e03ba540774ba5f7b5fc2214877 291 TIGRFAM TIGR00552 nadE: NAD+ synthetase 35 290 4.7E-66 T 18-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TWT_405 1ddf5e03ba540774ba5f7b5fc2214877 291 Pfam PF02540 NAD synthase 41 281 9.6E-61 T 18-10-2018 IPR022310 NAD/GMP synthase TWT_405 1ddf5e03ba540774ba5f7b5fc2214877 291 SUPERFAMILY SSF52402 26 290 3.35E-71 T 18-10-2018 TWT_405 1ddf5e03ba540774ba5f7b5fc2214877 291 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 36 284 49.537 T 18-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TWT_328 23bd2a74d8400fde06013e5c8f9d72ef 361 Pfam PF13407 Periplasmic binding protein domain 55 325 1.2E-57 T 18-10-2018 IPR025997 Periplasmic binding protein TWT_328 23bd2a74d8400fde06013e5c8f9d72ef 361 SUPERFAMILY SSF53822 53 360 3.08E-58 T 18-10-2018 IPR028082 Periplasmic binding protein-like I TWT_328 23bd2a74d8400fde06013e5c8f9d72ef 361 Gene3D G3DSA:3.40.50.2300 156 358 2.7E-95 T 18-10-2018 TWT_328 23bd2a74d8400fde06013e5c8f9d72ef 361 Gene3D G3DSA:3.40.50.2300 54 345 2.7E-95 T 18-10-2018 TWT_770 399239367854bc29e09086d6a6141f6e 280 Gene3D G3DSA:1.10.150.240 80 145 1.7E-52 T 18-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TWT_770 399239367854bc29e09086d6a6141f6e 280 Gene3D G3DSA:3.40.50.1000 69 269 1.7E-52 T 18-10-2018 IPR023214 HAD superfamily TWT_770 399239367854bc29e09086d6a6141f6e 280 SUPERFAMILY SSF56784 59 276 6.67E-48 T 18-10-2018 IPR036412 HAD-like superfamily TWT_770 399239367854bc29e09086d6a6141f6e 280 Pfam PF13419 Haloacid dehalogenase-like hydrolase 69 249 2.6E-23 T 18-10-2018 TWT_587 8ee95f3272d883cc4f28dbd14e58ea06 181 Pfam PF01227 GTP cyclohydrolase I 13 153 2.9E-35 T 18-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TWT_587 8ee95f3272d883cc4f28dbd14e58ea06 181 SUPERFAMILY SSF55620 9 172 1.78E-37 T 18-10-2018 TWT_587 8ee95f3272d883cc4f28dbd14e58ea06 181 Gene3D G3DSA:3.30.1130.10 60 181 2.6E-29 T 18-10-2018 TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 273 323 2.1E-9 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 818 867 3.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 373 425 2.6E-10 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 1174 1223 3.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 586 637 2.0E-11 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 1085 1134 3.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 996 1045 3.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 907 956 3.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_202 c004c591fd21c47f99e3eb7dd5bd2d4f 1241 Pfam PF05345 Putative Ig domain 479 531 4.4E-10 T 18-10-2018 IPR008009 Putative Ig TWT_419 ae0a63389fab6fc99e6882a42f5ad22f 398 Pfam PF01594 AI-2E family transporter 76 392 2.3E-45 T 18-10-2018 IPR002549 Transmembrane protein TqsA-like TWT_533 7a185b8baf13ac0a2d7b201f12a3f91e 287 Gene3D G3DSA:3.20.10.10 124 286 1.9E-47 T 18-10-2018 TWT_533 7a185b8baf13ac0a2d7b201f12a3f91e 287 Pfam PF01063 Amino-transferase class IV 41 263 9.8E-40 T 18-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TWT_533 7a185b8baf13ac0a2d7b201f12a3f91e 287 SUPERFAMILY SSF56752 18 282 1.27E-51 T 18-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TWT_533 7a185b8baf13ac0a2d7b201f12a3f91e 287 Gene3D G3DSA:3.30.470.10 2 120 1.5E-18 T 18-10-2018 TWT_802 d6afafe06c7f341559880a0b6010d456 300 SUPERFAMILY SSF52540 42 291 5.32E-61 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_802 d6afafe06c7f341559880a0b6010d456 300 Gene3D G3DSA:3.40.50.300 39 296 1.8E-72 T 18-10-2018 TWT_802 d6afafe06c7f341559880a0b6010d456 300 Pfam PF13614 AAA domain 42 217 6.0E-56 T 18-10-2018 IPR025669 AAA domain TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 14 56 3.4E-7 T 18-10-2018 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 Gene3D G3DSA:3.40.50.150 70 302 2.3E-46 T 18-10-2018 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 198 269 1.8E-6 T 18-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 137 2.1E-7 T 18-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 PIRSF PIRSF017269 2 301 6.3E-94 T 18-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 Gene3D G3DSA:3.10.330.20 8 68 3.4E-10 T 18-10-2018 TWT_318 ac14d3f5cce6028cdbd0af1260259eef 322 SUPERFAMILY SSF53335 9 289 1.5E-49 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_177 d690a6a20932fb5a5f09fedb16ec3136 346 Gene3D G3DSA:3.40.50.300 49 286 8.7E-56 T 18-10-2018 TWT_177 d690a6a20932fb5a5f09fedb16ec3136 346 SMART SM00382 81 258 1.8E-13 T 18-10-2018 IPR003593 AAA+ ATPase domain TWT_177 d690a6a20932fb5a5f09fedb16ec3136 346 Pfam PF00005 ABC transporter 73 209 1.8E-25 T 18-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TWT_177 d690a6a20932fb5a5f09fedb16ec3136 346 SUPERFAMILY SSF52540 54 282 1.7E-52 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_774 69205aeb564e47cbc1d7daa840ce5b66 149 Gene3D G3DSA:2.60.200.20 31 149 2.6E-24 T 18-10-2018 TWT_774 69205aeb564e47cbc1d7daa840ce5b66 149 SUPERFAMILY SSF49879 45 147 5.74E-27 T 18-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TWT_774 69205aeb564e47cbc1d7daa840ce5b66 149 Pfam PF00498 FHA domain 77 142 5.2E-19 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_774 69205aeb564e47cbc1d7daa840ce5b66 149 SMART SM00240 75 125 1.2E-14 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_755 cf46b9430b912dc04027fbe4d212077d 202 SUPERFAMILY SSF53254 2 188 2.36E-32 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_755 cf46b9430b912dc04027fbe4d212077d 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 185 1.4E-27 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_755 cf46b9430b912dc04027fbe4d212077d 202 Gene3D G3DSA:3.40.50.1240 1 194 1.3E-25 T 18-10-2018 IPR029033 Histidine phosphatase superfamily TWT_755 cf46b9430b912dc04027fbe4d212077d 202 SMART SM00855 3 153 1.7E-8 T 18-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TWT_493 accb1c20564f2ca143365d5c940f4364 757 SUPERFAMILY SSF53474 486 726 3.74E-43 T 18-10-2018 IPR029058 Alpha/Beta hydrolase fold TWT_493 accb1c20564f2ca143365d5c940f4364 757 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 32 471 2.3E-76 T 18-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 569 588 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 678 700 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 515 533 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 658 673 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 541 565 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 599 619 1.1E-48 T 18-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TWT_493 accb1c20564f2ca143365d5c940f4364 757 Pfam PF00326 Prolyl oligopeptidase family 530 744 8.9E-62 T 18-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TWT_493 accb1c20564f2ca143365d5c940f4364 757 SUPERFAMILY SSF50993 29 474 2.3E-67 T 18-10-2018 TWT_428 ed7e7e74114a620fbb9a0dee9970d571 172 Pfam PF00430 ATP synthase B/B' CF(0) 17 145 2.3E-24 T 18-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TWT_428 ed7e7e74114a620fbb9a0dee9970d571 172 SUPERFAMILY SSF81573 72 131 4.84E-11 T 18-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TWT_428 ed7e7e74114a620fbb9a0dee9970d571 172 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 21 164 8.9E-21 T 18-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 TWT_428 ed7e7e74114a620fbb9a0dee9970d571 172 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 148 11.83 T 18-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TWT_133 9ec16726e36ebb3bc00e92cfc002ac24 260 Gene3D G3DSA:3.40.50.300 1 259 8.5E-35 T 18-10-2018 TWT_133 9ec16726e36ebb3bc00e92cfc002ac24 260 SUPERFAMILY SSF52540 1 259 1.3E-25 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_133 9ec16726e36ebb3bc00e92cfc002ac24 260 Pfam PF13614 AAA domain 2 133 3.8E-9 T 18-10-2018 IPR025669 AAA domain TWT_444 49ac5f57766bb3d153610a9a20b9399c 285 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 228 239 - T 18-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 TWT_444 49ac5f57766bb3d153610a9a20b9399c 285 SUPERFAMILY SSF56219 8 274 1.27E-58 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_444 49ac5f57766bb3d153610a9a20b9399c 285 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 8 274 4.6E-56 T 18-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TWT_444 49ac5f57766bb3d153610a9a20b9399c 285 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 10 267 2.3E-13 T 18-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TWT_444 49ac5f57766bb3d153610a9a20b9399c 285 Gene3D G3DSA:3.60.10.10 7 275 2.1E-56 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_649 59f3cf2c9eb61b17a6a1277e44cb4183 226 SMART SM00934 13 217 5.1E-18 T 18-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_649 59f3cf2c9eb61b17a6a1277e44cb4183 226 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 215 2.4E-12 T 18-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TWT_649 59f3cf2c9eb61b17a6a1277e44cb4183 226 SUPERFAMILY SSF51366 10 225 2.07E-31 T 18-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TWT_649 59f3cf2c9eb61b17a6a1277e44cb4183 226 Gene3D G3DSA:3.20.20.70 10 226 1.2E-65 T 18-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TWT_804 180b8b953f46e8d561da3a580ab79641 173 Gene3D G3DSA:3.30.1370.50 105 173 3.2E-9 T 18-10-2018 IPR036867 R3H domain superfamily GO:0003676 TWT_804 180b8b953f46e8d561da3a580ab79641 173 SMART SM00393 95 173 6.4E-8 T 18-10-2018 IPR001374 R3H domain GO:0003676 TWT_804 180b8b953f46e8d561da3a580ab79641 173 Pfam PF01424 R3H domain 132 171 8.5E-14 T 18-10-2018 IPR001374 R3H domain GO:0003676 TWT_804 180b8b953f46e8d561da3a580ab79641 173 SUPERFAMILY SSF82708 133 172 2.75E-10 T 18-10-2018 IPR036867 R3H domain superfamily GO:0003676 TWT_757 147c3f421371ad74b10daa2dfce66923 228 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 208 8.1E-31 T 18-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TWT_514 5eb6dec991bbc5c07d198468a1d661e9 123 Gene3D G3DSA:3.30.110.150 39 123 3.1E-23 T 18-10-2018 IPR038594 SepF-like superfamily TWT_514 5eb6dec991bbc5c07d198468a1d661e9 123 Pfam PF04472 Cell division protein SepF 44 115 6.1E-20 T 18-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TWT_514 5eb6dec991bbc5c07d198468a1d661e9 123 Hamap MF_01197 Cell division protein SepF [sepF]. 2 123 17.577 T 18-10-2018 IPR023052 Cell division protein SepF GO:0090529 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 Pfam PF01209 ubiE/COQ5 methyltransferase family 17 235 7.6E-52 T 18-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 SUPERFAMILY SSF53335 15 232 3.8E-47 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 145 159 - T 18-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 19 234 1.9E-65 T 18-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 10 236 32.046 T 18-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 30 45 - T 18-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TWT_053 b9903e3dfe5d5105d42e9941b301cee9 239 Gene3D G3DSA:3.40.50.150 25 237 1.0E-60 T 18-10-2018 TWT_241 3b648dc92c273537c3e57bea5eb1e0db 446 Pfam PF07687 Peptidase dimerisation domain 191 341 2.8E-12 T 18-10-2018 IPR011650 Peptidase M20, dimerisation domain TWT_241 3b648dc92c273537c3e57bea5eb1e0db 446 Gene3D G3DSA:3.40.630.10 15 434 4.5E-103 T 18-10-2018 TWT_241 3b648dc92c273537c3e57bea5eb1e0db 446 Gene3D G3DSA:3.30.70.360 199 362 4.5E-103 T 18-10-2018 TWT_241 3b648dc92c273537c3e57bea5eb1e0db 446 SUPERFAMILY SSF53187 6 443 1.47E-46 T 18-10-2018 TWT_241 3b648dc92c273537c3e57bea5eb1e0db 446 Pfam PF01546 Peptidase family M20/M25/M40 81 440 2.1E-29 T 18-10-2018 IPR002933 Peptidase M20 GO:0016787 TWT_383 7ea550d81f0e3ecdd7ba5bee0c0d45fa 472 Pfam PF03772 Competence protein 195 457 3.8E-34 T 18-10-2018 IPR004477 ComEC/Rec2-related protein TWT_383 7ea550d81f0e3ecdd7ba5bee0c0d45fa 472 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 217 391 4.2E-15 T 18-10-2018 IPR004477 ComEC/Rec2-related protein TWT_121 89bf7dae2ad66a4a7a0a439522ae486f 627 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 172 249 1.1E-6 T 18-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 TWT_121 89bf7dae2ad66a4a7a0a439522ae486f 627 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 392 626 1.8E-15 T 18-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 TWT_303 0ed160e630ab5a2402821076a1f573f4 98 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 23 93 7.0E-18 T 18-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TWT_303 0ed160e630ab5a2402821076a1f573f4 98 Pfam PF03840 Preprotein translocase SecG subunit 24 92 3.5E-15 T 18-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TWT_303 0ed160e630ab5a2402821076a1f573f4 98 PRINTS PR01651 Protein-export SecG membrane protein signature 43 57 9.0E-8 T 18-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TWT_303 0ed160e630ab5a2402821076a1f573f4 98 PRINTS PR01651 Protein-export SecG membrane protein signature 23 43 9.0E-8 T 18-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TWT_303 0ed160e630ab5a2402821076a1f573f4 98 PRINTS PR01651 Protein-export SecG membrane protein signature 74 96 9.0E-8 T 18-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TWT_392 64f27afd611a0433636cc9ac8f9807f9 231 Gene3D G3DSA:3.40.430.10 6 225 5.7E-22 T 18-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TWT_392 64f27afd611a0433636cc9ac8f9807f9 231 Pfam PF01872 RibD C-terminal domain 20 179 1.8E-12 T 18-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TWT_392 64f27afd611a0433636cc9ac8f9807f9 231 SUPERFAMILY SSF53597 20 183 3.79E-19 T 18-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TWT_060 6a97aa2ab84091a401486e112ac51f9d 321 Pfam PF01032 FecCD transport family 20 317 2.2E-74 T 18-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TWT_060 6a97aa2ab84091a401486e112ac51f9d 321 SUPERFAMILY SSF81345 11 317 3.27E-59 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_060 6a97aa2ab84091a401486e112ac51f9d 321 Gene3D G3DSA:1.10.3470.10 4 320 1.0E-66 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_805 ebbaf4cfe976b6f20f6abcbf853e0526 333 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 66 291 3.5E-56 T 18-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TWT_805 ebbaf4cfe976b6f20f6abcbf853e0526 333 Pfam PF02096 60Kd inner membrane protein 67 290 2.9E-49 T 18-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TWT_151 f00141e189297cdf645036bb77f3db03 460 PRINTS PR01217 Proline rich extensin signature 80 101 5.1E-9 T 18-10-2018 TWT_151 f00141e189297cdf645036bb77f3db03 460 PRINTS PR01217 Proline rich extensin signature 66 78 5.1E-9 T 18-10-2018 TWT_151 f00141e189297cdf645036bb77f3db03 460 PRINTS PR01217 Proline rich extensin signature 126 143 5.1E-9 T 18-10-2018 TWT_151 f00141e189297cdf645036bb77f3db03 460 PRINTS PR01217 Proline rich extensin signature 107 123 5.1E-9 T 18-10-2018 TWT_151 f00141e189297cdf645036bb77f3db03 460 PRINTS PR01217 Proline rich extensin signature 144 169 5.1E-9 T 18-10-2018 TWT_498 2ff4e6edf453a2364b683ec81dcebe50 461 Pfam PF08245 Mur ligase middle domain 52 262 1.2E-14 T 18-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TWT_498 2ff4e6edf453a2364b683ec81dcebe50 461 Gene3D G3DSA:3.40.1190.10 38 281 9.6E-31 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_498 2ff4e6edf453a2364b683ec81dcebe50 461 SUPERFAMILY SSF53623 38 266 2.18E-29 T 18-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 80 7.9E-5 T 18-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 285 303 7.9E-5 T 18-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 Gene3D G3DSA:3.40.50.2300 181 303 7.3E-66 T 18-10-2018 TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 Gene3D G3DSA:3.40.50.2300 66 372 7.3E-66 T 18-10-2018 TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 SUPERFAMILY SSF53822 65 397 5.05E-62 T 18-10-2018 IPR028082 Periplasmic binding protein-like I TWT_561 5c6beba16896caaa02e0ad65b1372a2f 398 Pfam PF13458 Periplasmic binding protein 65 390 3.5E-40 T 18-10-2018 IPR028081 Leucine-binding protein domain TWT_753 d9e5af6b66fe0477874f358e17deb2d3 167 SUPERFAMILY SSF52833 41 127 2.95E-8 T 18-10-2018 IPR036249 Thioredoxin-like superfamily TWT_753 d9e5af6b66fe0477874f358e17deb2d3 167 Gene3D G3DSA:3.40.30.10 40 141 8.8E-17 T 18-10-2018 TWT_753 d9e5af6b66fe0477874f358e17deb2d3 167 Pfam PF05768 Glutaredoxin-like domain (DUF836) 40 128 3.0E-20 T 18-10-2018 IPR008554 Glutaredoxin-like TWT_731 f5e9bec76b5b1c8df72e2073447b4ebe 241 Gene3D G3DSA:3.40.50.10090 127 239 3.8E-11 T 18-10-2018 TWT_731 f5e9bec76b5b1c8df72e2073447b4ebe 241 SUPERFAMILY SSF69618 7 239 9.42E-34 T 18-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_731 f5e9bec76b5b1c8df72e2073447b4ebe 241 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 235 9.2E-29 T 18-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TWT_731 f5e9bec76b5b1c8df72e2073447b4ebe 241 Gene3D G3DSA:3.40.50.10090 2 119 3.3E-12 T 18-10-2018 TWT_488 4c69449ef2c1064228681b5206518a76 155 Pfam PF11292 Protein of unknown function (DUF3093) 4 148 5.4E-40 T 18-10-2018 IPR021443 Protein of unknown function DUF3093 TWT_015 9f8bdc1e92ce19cdd0e20bde714bc801 427 SUPERFAMILY SSF49313 62 133 5.96E-5 T 18-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 TWT_015 9f8bdc1e92ce19cdd0e20bde714bc801 427 Gene3D G3DSA:2.60.40.10 43 135 1.3E-7 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_015 9f8bdc1e92ce19cdd0e20bde714bc801 427 Pfam PF05345 Putative Ig domain 361 398 1.3E-9 T 18-10-2018 IPR008009 Putative Ig TWT_015 9f8bdc1e92ce19cdd0e20bde714bc801 427 Pfam PF05345 Putative Ig domain 173 212 1.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_015 9f8bdc1e92ce19cdd0e20bde714bc801 427 Pfam PF05345 Putative Ig domain 71 122 6.8E-10 T 18-10-2018 IPR008009 Putative Ig TWT_218 2eef4dcd08b1042bd00b80917a769be9 113 Pfam PF11239 Protein of unknown function (DUF3040) 16 93 3.9E-18 T 18-10-2018 IPR021401 Protein of unknown function DUF3040 TWT_398 a857ae7133b5815f1df2f483fd458474 203 SUPERFAMILY SSF52833 10 166 1.47E-12 T 18-10-2018 IPR036249 Thioredoxin-like superfamily TWT_398 a857ae7133b5815f1df2f483fd458474 203 Gene3D G3DSA:3.40.30.10 5 203 4.6E-47 T 18-10-2018 TWT_200 ef345e883526fada9b3f1b888183c8bb 303 PIRSF PIRSF003097 1 303 2.5E-60 T 18-10-2018 IPR004513 Cell division protein FtsX GO:0016021 TWT_200 ef345e883526fada9b3f1b888183c8bb 303 Gene3D G3DSA:3.30.70.3040 43 165 9.9E-24 T 18-10-2018 TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 34 53 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 269 295 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 129 153 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 363 382 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 53 69 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 418 435 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 153 174 9.4E-23 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 Pfam PF03023 MviN-like protein 39 471 8.7E-70 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_799 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 6 515 1.5E-70 T 18-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 SUPERFAMILY SSF53098 9 134 8.65E-25 T 18-10-2018 IPR012337 Ribonuclease H-like superfamily TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 11 133 1.8E-18 T 18-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 Gene3D G3DSA:3.30.420.140 8 140 9.7E-29 T 18-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 8 136 17.565 T 18-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 SMART SM00732 8 101 1.6E-13 T 18-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TWT_375 190a1696b79fbb6fb63e4cad714ab34b 145 Pfam PF03652 Holliday junction resolvase 10 133 4.1E-28 T 18-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TWT_007 ed3c42d4c57dec219425538ba1f493b0 126 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 12 124 4.0E-23 T 18-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane TWT_037 0b7cfc06c1abd86e83bbfd43726c9dbf 146 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 33 128 3.6E-24 T 18-10-2018 IPR019277 Protein of unknown function DUF2304 TWT_512 0164dbcead83d1778cd8371b830b598d 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 1.3E-10 T 18-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TWT_512 0164dbcead83d1778cd8371b830b598d 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 1.3E-10 T 18-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TWT_512 0164dbcead83d1778cd8371b830b598d 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 128 144 1.3E-10 T 18-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TWT_512 0164dbcead83d1778cd8371b830b598d 150 Pfam PF01252 Signal peptidase (SPase) II 12 143 6.8E-26 T 18-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TWT_512 0164dbcead83d1778cd8371b830b598d 150 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 3 150 12.899 T 18-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TWT_138 0407ad23d4472e067f0deca7b222fe29 201 Pfam PF02361 Cobalt transport protein 34 200 4.5E-6 T 18-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TWT_689 c64f8796deeaf0010689ef69567075dc 215 SUPERFAMILY SSF55821 3 201 3.43E-72 T 18-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TWT_689 c64f8796deeaf0010689ef69567075dc 215 Gene3D G3DSA:3.90.870.10 1 205 5.2E-82 T 18-10-2018 TWT_689 c64f8796deeaf0010689ef69567075dc 215 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 197 2.0E-65 T 18-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_689 c64f8796deeaf0010689ef69567075dc 215 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 197 7.5E-76 T 18-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TWT_759 6e58ab38a8f3d78f35f98a69f3a8406f 316 Pfam PF01578 Cytochrome C assembly protein 110 311 2.0E-38 T 18-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TWT_759 6e58ab38a8f3d78f35f98a69f3a8406f 316 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 88 314 3.4E-67 T 18-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 TWT_685 6637295a84a5a81e73367de7174b082e 281 Gene3D G3DSA:3.60.10.10 1 280 7.1E-62 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_685 6637295a84a5a81e73367de7174b082e 281 SUPERFAMILY SSF56219 2 280 3.14E-55 T 18-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TWT_685 6637295a84a5a81e73367de7174b082e 281 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 279 2.1E-47 T 18-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TWT_685 6637295a84a5a81e73367de7174b082e 281 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 254 4.4E-14 T 18-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 Pfam PF01555 DNA methylase 34 274 1.3E-46 T 18-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 95 114 2.1E-23 T 18-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 217 239 2.1E-23 T 18-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 240 254 2.1E-23 T 18-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 33 45 2.1E-23 T 18-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 SUPERFAMILY SSF53335 11 280 1.13E-68 T 18-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TWT_771 93b14951ed8448499ee6f707fb7ec3d7 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 36 42 - T 18-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TWT_090 47ab99470bef0f3bbeb39db8bca1f02f 254 Gene3D G3DSA:3.60.40.10 6 254 1.0E-52 T 18-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TWT_090 47ab99470bef0f3bbeb39db8bca1f02f 254 Pfam PF13672 Protein phosphatase 2C 34 214 1.1E-9 T 18-10-2018 TWT_090 47ab99470bef0f3bbeb39db8bca1f02f 254 SUPERFAMILY SSF81606 22 252 3.53E-52 T 18-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TWT_090 47ab99470bef0f3bbeb39db8bca1f02f 254 SMART SM00332 7 249 9.0E-23 T 18-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TWT_090 47ab99470bef0f3bbeb39db8bca1f02f 254 SMART SM00331 13 251 3.1E-14 T 18-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TWT_608 b36f60920543008604a0495d54cb258f 347 Pfam PF07861 WisP family N-Terminal Region 71 309 1.4E-161 T 18-10-2018 IPR012503 WisP, N-terminal TWT_270 6ed0e50238b9a3ee7c92293a6cb17acf 163 Pfam PF02699 Preprotein translocase subunit 7 79 2.0E-11 T 18-10-2018 IPR003849 Preprotein translocase YajC TWT_270 6ed0e50238b9a3ee7c92293a6cb17acf 163 SMART SM01323 1 81 1.4E-17 T 18-10-2018 IPR003849 Preprotein translocase YajC TWT_234 5ee4fa069b7c1110492349cf5c2f31e3 143 SUPERFAMILY SSF49879 28 136 1.42E-27 T 18-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TWT_234 5ee4fa069b7c1110492349cf5c2f31e3 143 SMART SM00240 65 115 1.4E-11 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_234 5ee4fa069b7c1110492349cf5c2f31e3 143 Gene3D G3DSA:2.60.200.20 19 141 1.2E-30 T 18-10-2018 TWT_234 5ee4fa069b7c1110492349cf5c2f31e3 143 Pfam PF00498 FHA domain 68 129 1.1E-16 T 18-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TWT_129 4e70c343b509843deebee9456fe85ccf 254 Gene3D G3DSA:3.40.50.2020 37 243 7.7E-7 T 18-10-2018 TWT_129 4e70c343b509843deebee9456fe85ccf 254 SUPERFAMILY SSF53271 70 221 5.86E-10 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_697 b50e961281c7431c449a97718e08510c 136 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 29 133 2.4E-27 T 18-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like TWT_692 a8afb747eca2931690dfe99897f380ad 209 SUPERFAMILY SSF52499 8 205 1.44E-35 T 18-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TWT_692 a8afb747eca2931690dfe99897f380ad 209 Pfam PF00857 Isochorismatase family 21 204 3.5E-24 T 18-10-2018 IPR000868 Isochorismatase-like GO:0003824 TWT_692 a8afb747eca2931690dfe99897f380ad 209 Gene3D G3DSA:3.40.50.850 21 207 2.0E-46 T 18-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TWT_132 708af21665980cd2d2f620bdd9fb679b 254 Pfam PF08666 SAF domain 39 98 1.3E-4 T 18-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TWT_721 66953d079f475c36cc4d23048f4affff 140 SUPERFAMILY SSF54637 10 138 1.13E-26 T 18-10-2018 IPR029069 HotDog domain superfamily TWT_721 66953d079f475c36cc4d23048f4affff 140 Pfam PF13452 N-terminal half of MaoC dehydratase 11 95 2.0E-17 T 18-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 TWT_721 66953d079f475c36cc4d23048f4affff 140 Gene3D G3DSA:3.10.129.10 4 140 6.9E-27 T 18-10-2018 TWT_721 66953d079f475c36cc4d23048f4affff 140 PIRSF PIRSF018072 2 140 4.1E-43 T 18-10-2018 IPR016709 Uncharacterised protein family UPF0336 TWT_767 f549a636ec0f12c6b6d62710ea4861be 147 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 114 1.1E-6 T 18-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III TWT_504 1ce9a2a430787a8a818b898fd26b24ae 167 Pfam PF12028 Protein of unknown function (DUF3515) 20 157 2.1E-12 T 18-10-2018 IPR021903 Protein of unknown function DUF3515 TWT_374 9f824bd675942605bef8954662d88c31 395 Gene3D G3DSA:1.10.8.1150 95 162 5.3E-7 T 18-10-2018 TWT_374 9f824bd675942605bef8954662d88c31 395 Pfam PF02618 YceG-like family 99 381 4.1E-67 T 18-10-2018 IPR003770 Endolytic murein transglycosylase TWT_374 9f824bd675942605bef8954662d88c31 395 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 70 388 29.648 T 18-10-2018 IPR003770 Endolytic murein transglycosylase TWT_374 9f824bd675942605bef8954662d88c31 395 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 62 388 5.0E-55 T 18-10-2018 IPR003770 Endolytic murein transglycosylase TWT_214 577a315aa6882062fb1808c602d44940 221 Pfam PF01553 Acyltransferase 25 148 1.3E-24 T 18-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TWT_214 577a315aa6882062fb1808c602d44940 221 SMART SM00563 33 152 1.3E-30 T 18-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TWT_214 577a315aa6882062fb1808c602d44940 221 SUPERFAMILY SSF69593 2 214 9.29E-46 T 18-10-2018 TWT_329 4566531b4ed687e2f9c9cec87911f6d5 410 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 377 4.5E-36 T 18-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TWT_798 62b306526be3f304f6c581f305996795 244 Gene3D G3DSA:3.40.50.10320 9 243 6.3E-54 T 18-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TWT_798 62b306526be3f304f6c581f305996795 244 Pfam PF02585 GlcNAc-PI de-N-acetylase 15 163 6.7E-28 T 18-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TWT_798 62b306526be3f304f6c581f305996795 244 SUPERFAMILY SSF102588 12 217 4.97E-46 T 18-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TWT_432 82a7b5b9bf8ade3307eb75a8ac7e5159 366 ProSitePatterns PS01348 MraY family signature 2. 152 163 - T 18-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_432 82a7b5b9bf8ade3307eb75a8ac7e5159 366 Pfam PF00953 Glycosyl transferase family 4 82 239 1.9E-33 T 18-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TWT_193 d91151cd1a7918cf397b6fb9870aaa17 139 Pfam PF07811 TadE-like protein 23 65 4.5E-10 T 18-10-2018 IPR012495 TadE-like TWT_640 b945b8ce2dc4fd7fa417dba24c12c06b 482 Pfam PF02646 RmuC family 130 418 1.4E-69 T 18-10-2018 IPR003798 DNA recombination RmuC TWT_141 808450c34890886ddf41537ca730c143 321 SUPERFAMILY SSF161098 110 299 6.02E-23 T 18-10-2018 IPR035906 MetI-like superfamily TWT_141 808450c34890886ddf41537ca730c143 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 316 3.3E-29 T 18-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TWT_141 808450c34890886ddf41537ca730c143 321 Gene3D G3DSA:1.10.3720.10 102 314 3.1E-22 T 18-10-2018 IPR035906 MetI-like superfamily TWT_147 e95612c7ef370334a58c97bb9551807c 251 SUPERFAMILY SSF52540 9 237 8.07E-43 T 18-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TWT_147 e95612c7ef370334a58c97bb9551807c 251 Gene3D G3DSA:3.40.50.300 3 241 2.8E-55 T 18-10-2018 TWT_147 e95612c7ef370334a58c97bb9551807c 251 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 36 173 1.5E-10 T 18-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 TWT_148 b7129fbab5268fe593b2934be7672eaf 301 Pfam PF05345 Putative Ig domain 116 160 9.2E-7 T 18-10-2018 IPR008009 Putative Ig TWT_148 b7129fbab5268fe593b2934be7672eaf 301 Pfam PF05345 Putative Ig domain 17 56 2.7E-11 T 18-10-2018 IPR008009 Putative Ig TWT_518 4211eed22377a1ef22ba3e89a74dc97b 420 SUPERFAMILY SSF56112 69 281 9.39E-8 T 18-10-2018 IPR011009 Protein kinase-like domain superfamily TWT_518 4211eed22377a1ef22ba3e89a74dc97b 420 Gene3D G3DSA:3.90.1200.10 138 338 4.9E-18 T 18-10-2018 TWT_664 1b953f0924206c7bf6cc0de978657934 284 Gene3D G3DSA:1.10.3470.10 39 268 9.7E-8 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_664 1b953f0924206c7bf6cc0de978657934 284 Pfam PF00950 ABC 3 transport family 11 263 8.8E-72 T 18-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TWT_664 1b953f0924206c7bf6cc0de978657934 284 SUPERFAMILY SSF81345 3 261 1.83E-37 T 18-10-2018 IPR037294 ABC transporter, BtuC-like TWT_178 270843f8239d4d1fdb03d2c06ee3224d 259 Pfam PF01061 ABC-2 type transporter 14 208 6.8E-11 T 18-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TWT_178 270843f8239d4d1fdb03d2c06ee3224d 259 PIRSF PIRSF006648 2 252 5.6E-16 T 18-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TWT_513 aaaddaef160377dd735ddb5baa14577b 193 Pfam PF05103 DivIVA protein 21 149 3.3E-13 T 18-10-2018 IPR007793 DivIVA family TWT_513 aaaddaef160377dd735ddb5baa14577b 193 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 21 56 6.3E-14 T 18-10-2018 IPR019933 DivIVA domain TWT_626 813cfc1d6b0525dacadeda22a7022b41 522 Pfam PF03699 Uncharacterised protein family (UPF0182) 19 388 2.8E-131 T 18-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TWT_507 1eb1e34e68e7c227bccbcb774d0c2f26 241 SMART SM00563 39 166 4.8E-25 T 18-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TWT_507 1eb1e34e68e7c227bccbcb774d0c2f26 241 Pfam PF01553 Acyltransferase 31 159 1.5E-21 T 18-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TWT_507 1eb1e34e68e7c227bccbcb774d0c2f26 241 SUPERFAMILY SSF69593 4 223 1.29E-45 T 18-10-2018 TWT_589 e5a4dd3f3025d7ad4ed71a52563f63d7 183 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 20 182 6.9E-57 T 18-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 TWT_589 e5a4dd3f3025d7ad4ed71a52563f63d7 183 Gene3D G3DSA:3.40.50.2020 7 183 3.5E-59 T 18-10-2018 TWT_589 e5a4dd3f3025d7ad4ed71a52563f63d7 183 SUPERFAMILY SSF53271 17 182 5.24E-46 T 18-10-2018 IPR029057 Phosphoribosyltransferase-like TWT_589 e5a4dd3f3025d7ad4ed71a52563f63d7 183 Pfam PF00156 Phosphoribosyl transferase domain 27 168 5.0E-22 T 18-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TWT_212 dd5c189545d35296a719ad767d96451c 912 Pfam PF05345 Putative Ig domain 639 682 6.8E-12 T 18-10-2018 IPR008009 Putative Ig TWT_212 dd5c189545d35296a719ad767d96451c 912 Pfam PF05345 Putative Ig domain 528 571 6.8E-12 T 18-10-2018 IPR008009 Putative Ig TWT_212 dd5c189545d35296a719ad767d96451c 912 Pfam PF05345 Putative Ig domain 861 899 9.1E-7 T 18-10-2018 IPR008009 Putative Ig TWT_212 dd5c189545d35296a719ad767d96451c 912 Pfam PF05345 Putative Ig domain 417 460 6.8E-12 T 18-10-2018 IPR008009 Putative Ig TWT_212 dd5c189545d35296a719ad767d96451c 912 Pfam PF05345 Putative Ig domain 750 793 6.8E-12 T 18-10-2018 IPR008009 Putative Ig TWT_025 a117d846f7f3cf9b2f75d5daff467483 153 Pfam PF04138 GtrA-like protein 25 149 8.4E-23 T 18-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TWT_486 a3af45db14e12773926985c5c693a927 207 Pfam PF12502 Protein of unknown function (DUF3710) 24 199 3.3E-53 T 18-10-2018 IPR022183 Protein of unknown function DUF3710 TWT_445 232275203eb880ba524cd6f1d64fe9a7 280 Pfam PF01148 Cytidylyltransferase family 30 272 5.9E-51 T 18-10-2018 TWT_445 232275203eb880ba524cd6f1d64fe9a7 280 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 236 262 - T 18-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TWT_004 1a95c40d6591b00b1f6aa579ee0433f0 144 Pfam PF05258 Protein of unknown function (DUF721) 39 121 1.5E-8 T 18-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 TWT_627 4880de8b85f8f6f9818bfbb376f9034f 488 Pfam PF03699 Uncharacterised protein family (UPF0182) 18 463 8.0E-124 T 18-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TWT_039 24234509d6a5a9107f516b7748dde8b5 613 Pfam PF09913 Predicted membrane protein (DUF2142) 46 427 3.1E-76 T 18-10-2018 IPR018674 Protein of unknown function DUF2142, membrane TWT_409 a8d5f1707671e83781e4265fcba4f812 201 PIRSF PIRSF037394 13 201 7.6E-57 T 18-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted TWT_409 a8d5f1707671e83781e4265fcba4f812 201 Pfam PF09819 ABC-type cobalt transport system, permease component 24 141 1.5E-29 T 18-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted TWT_407 a6d3b13afbf2457f3f44985f67b76058 242 Pfam PF02361 Cobalt transport protein 14 204 1.5E-5 T 18-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TWT_245 8f62db7b9c041794dac05fe0c7923b83 139 Pfam PF12270 Cytochrome c oxidase subunit IV 3 136 2.8E-32 T 18-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TWT_240 0ab1a04327ea7f1f065088ca6485d9a9 173 Pfam PF11241 Protein of unknown function (DUF3043) 3 165 8.9E-47 T 18-10-2018 IPR021403 Protein of unknown function DUF3043 TWT_250 94aa7ef93d67e5cc113c29ae3061f2d2 164 Pfam PF11343 Protein of unknown function (DUF3145) 13 159 2.1E-52 T 18-10-2018 IPR021491 Protein of unknown function DUF3145 TWT_699 cfea03e0f686ee8c45ddaf76090a34bd 68 Pfam PF14029 Protein of unknown function (DUF4244) 15 65 2.8E-20 T 18-10-2018 IPR025338 Protein of unknown function DUF4244 TWT_052 78795dabd222c1ee9aecd9c8a0b953ac 434 Gene3D G3DSA:3.60.120.10 24 434 9.0E-62 T 18-10-2018 IPR005801 ADC synthase GO:0009058 TWT_052 78795dabd222c1ee9aecd9c8a0b953ac 434 Pfam PF00425 chorismate binding enzyme 161 425 1.3E-64 T 18-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TWT_052 78795dabd222c1ee9aecd9c8a0b953ac 434 SUPERFAMILY SSF56322 38 433 5.76E-66 T 18-10-2018 IPR005801 ADC synthase GO:0009058 TWT_775 6182fea61adf6b5d460110cb704bd2fb 448 Pfam PF01098 Cell cycle protein 80 438 4.2E-67 T 18-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TWT_140 ecb0c4a5024a459e44c96862968a4e7c 332 SUPERFAMILY SSF161098 112 315 1.31E-13 T 18-10-2018 IPR035906 MetI-like superfamily TWT_140 ecb0c4a5024a459e44c96862968a4e7c 332 Gene3D G3DSA:1.10.3720.10 105 321 1.5E-17 T 18-10-2018 IPR035906 MetI-like superfamily TWT_140 ecb0c4a5024a459e44c96862968a4e7c 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 327 8.5E-36 T 18-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TWT_180 dd6d75e5dd853489a7f27f941a31c90c 488 Pfam PF01554 MatE 15 172 6.7E-12 T 18-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TWT_617 0b71724ba0e6460ad96e5d60e95c0b22 448 Gene3D G3DSA:2.60.40.10 325 399 1.1E-5 T 18-10-2018 IPR013783 Immunoglobulin-like fold TWT_191 fe9b25ff80b7073fe51d676629443b1e 298 Pfam PF00482 Type II secretion system (T2SS), protein F 166 289 1.4E-13 T 18-10-2018 IPR018076 Type II secretion system F domain TWT_279 fce22e1480a5f2b1d8b11de49f8f9735 224 Pfam PF09348 Domain of unknown function (DUF1990) 130 200 1.8E-4 T 18-10-2018 IPR018960 Domain of unknown function DUF1990 TWT_279 fce22e1480a5f2b1d8b11de49f8f9735 224 Pfam PF09348 Domain of unknown function (DUF1990) 40 99 4.6E-6 T 18-10-2018 IPR018960 Domain of unknown function DUF1990 TWT_489 5143d1d16671ad3ef6f6a92b5bc8b7ad 92 Pfam PF13834 Domain of unknown function (DUF4193) 2 91 7.6E-29 T 18-10-2018 IPR025242 Protein of unknown function DUF4193 TWT_195 d4d5b5fd364bdab0bbff8c2897760a35 228 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 91 136 9.8E-5 T 18-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal TWT_322 dd1113a416355b28425d233692493870 89 Pfam PF11238 Protein of unknown function (DUF3039) 32 87 2.1E-24 T 18-10-2018 IPR021400 Protein of unknown function DUF3039 TWT_524 ec9b8e319e299888273abadeca43ba69 193 Pfam PF06210 Protein of unknown function (DUF1003) 65 167 2.5E-26 T 18-10-2018 IPR010406 Protein of unknown function DUF1003 TWT_782 9208e1afb002ac2d44ae3268972bf605 146 Pfam PF04977 Septum formation initiator 25 102 1.8E-16 T 18-10-2018 IPR007060 Septum formation initiator FtsL/DivIC