locus-tag	class	description
Trad_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Trad_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Trad_0003	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Trad_0005	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Trad_0006	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Trad_0007	ENOG4107YH6	single-stranded DNA-binding protein
Trad_0008	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
Trad_0011	ENOG4105CFG	Acts as a chaperone (By similarity)
Trad_0012	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Trad_0013	ENOG4105DVC	DnaJ domain protein
Trad_0014	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Trad_0017	ENOG4105C7Z	Conserved Protein
Trad_0021	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Trad_0022	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Trad_0023	ENOG4105K46	50S ribosomal protein l27
Trad_0024	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Trad_0025	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Trad_0029	ENOG41080R2	UPF0102 protein
Trad_0030	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Trad_0031	ENOG4107QX3	carboxylase
Trad_0034	ENOG4105VG1	fes assembly suf system protein
Trad_0035	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Trad_0036	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Trad_0038	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Trad_0041	ENOG4105MS2	ribosomal subunit Interface protein
Trad_0042	ENOG41085FC	arsR family transcriptional regulator
Trad_0045	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Trad_0047	ENOG4105C4R	Atp-dependent dna helicase
Trad_0049	ENOG4105HYT	Uncharacterized metal-binding protein (DUF2227)
Trad_0051	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Trad_0057	ENOG4105C1G	acyl-Coa dehydrogenase
Trad_0059	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Trad_0060	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Trad_0061	ENOG4105F84	Ornithine cyclodeaminase
Trad_0062	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Trad_0063	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Trad_0064	ENOG4105DBV	ornithine carbamoyltransferase
Trad_0068	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Trad_0069	ENOG41080P6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Trad_0071	ENOG4105K5M	30s ribosomal protein S16
Trad_0072	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Trad_0076	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Trad_0080	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Trad_0081	ENOG4105D7N	magnesium and cobalt transport protein CorA
Trad_0082	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Trad_0083	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Trad_0086	ENOG4105C28	cystathionine
Trad_0091	ENOG4105ST3	Transcriptional regulator
Trad_0094	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Trad_0095	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Trad_0096	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Trad_0102	ENOG4105D3Q	Sugar transferase
Trad_0105	ENOG4105CKI	cobalamin synthesis protein
Trad_0112	ENOG4105EHG	Permease protein
Trad_0113	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Trad_0124	ENOG4105F38	ABC transporter, permease
Trad_0125	ENOG4105D38	putrescine abc transporter
Trad_0130	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Trad_0132	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Trad_0133	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Trad_0134	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Trad_0135	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Trad_0137	ENOG4105C26	Dehydrogenase
Trad_0139	ENOG4108JA2	transcriptioN-repair coupling factor
Trad_0140	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Trad_0145	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
Trad_0147	ENOG4107QM5	aconitate hydratase
Trad_0150	ENOG4105K63	Thioredoxin
Trad_0151	ENOG4107Y3Y	amidohydrolase
Trad_0155	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Trad_0158	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_0160	ENOG4108JQ7	(ABC) transporter
Trad_0162	ENOG4105EF1	ribulokinase
Trad_0163	ENOG4105E9Z	Nad-dependent epimerase dehydratase
Trad_0164	ENOG4108ZBR	Gcn5-related n-acetyltransferase
Trad_0165	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Trad_0168	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Trad_0170	ENOG4105D7V	transposase
Trad_0173	ENOG41084ZW	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Trad_0174	ENOG4105E66	phosphoriboisomerase A
Trad_0176	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Trad_0177	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Trad_0178	ENOG4105BZJ	Electron transfer flavoprotein
Trad_0179	ENOG4105C10	Electron transfer flavoprotein
Trad_0180	ENOG4105DF6	Fe-S oxidoreductase
Trad_0181	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Trad_0183	ENOG4105DG6	mannose-6-phosphate isomerase
Trad_0184	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Trad_0186	ENOG4105BZ1	(ABC) transporter
Trad_0192	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Trad_0194	ENOG4105CH5	extracellular solute-binding protein, family 7
Trad_0196	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Trad_0200	ENOG4105C5X	domain protein
Trad_0201	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Trad_0203	ENOG4105MCT	stage V sporulation protein S
Trad_0204	ENOG4105C7K	acetolactate synthase
Trad_0206	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Trad_0207	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Trad_0208	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Trad_0211	ENOG4107RUY	(E1 component), alpha subunit
Trad_0212	ENOG4105CPQ	Dehydrogenase
Trad_0215	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Trad_0216	ENOG4105WH1	Two component transcriptional regulator luxr family
Trad_0218	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Trad_0221	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Trad_0222	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Trad_0223	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Trad_0225	ENOG4105D52	delta-aminolevulinic acid dehydratase
Trad_0228	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Trad_0231	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Trad_0232	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Trad_0235	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Trad_0239	ENOG4108Z5K	methylglyoxal synthase
Trad_0240	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Trad_0242	ENOG4105CZN	Potassium uptake protein
Trad_0244	ENOG4105C1A	potassium transporter peripheral membrane
Trad_0245	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Trad_0246	ENOG4105CSV	Glutaminase
Trad_0248	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
Trad_0250	ENOG4108RPX	mosc domain containing protein
Trad_0252	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Trad_0253	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Trad_0255	ENOG4107QN1	sodium solute
Trad_0257	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Trad_0259	ENOG4105ZU5	s-layer protein
Trad_0261	ENOG4105JRK	feS assembly protein SufD
Trad_0265	ENOG4105C3K	feS assembly ATPase SufC
Trad_0266	ENOG4105D9P	serine threonine protein kinase
Trad_0267	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Trad_0268	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Trad_0270	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Trad_0271	ENOG4105BZU	Histidine kinase
Trad_0273	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Trad_0274	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Trad_0276	ENOG4105BZG	amino acid carrier protein
Trad_0277	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Trad_0287	ENOG4105ECP	epimerase
Trad_0291	ENOG41067S9	phage shock protein C, PspC
Trad_0292	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Trad_0293	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Trad_0297	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
Trad_0310	ENOG4105BZ1	(ABC) transporter
Trad_0312	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Trad_0313	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Trad_0315	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Trad_0316	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Trad_0318	ENOG41072GX	Peptidase M22 Glycoprotease
Trad_0323	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Trad_0324	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Trad_0325	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Trad_0326	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Trad_0328	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Trad_0331	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Trad_0335	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Trad_0336	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Trad_0340	ENOG4105KVH	Transcriptional regulator
Trad_0341	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Trad_0343	ENOG4107ZXI	Rhomboid family
Trad_0345	ENOG4105E0A	ABC, transporter
Trad_0350	ENOG4105EUJ	GTP cyclohydrolase i
Trad_0352	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
Trad_0354	ENOG4108X4Q	Hydrolase
Trad_0358	ENOG4105E33	succinate dehydrogenase
Trad_0359	ENOG4105CJW	magnesium transporter
Trad_0363	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Trad_0364	ENOG4105KME	endoribonuclease L-psp
Trad_0366	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Trad_0367	ENOG4105VG0	50S ribosomal protein l34
Trad_0369	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Trad_0370	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Trad_0373	ENOG4107Y2X	deaminase
Trad_0375	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Trad_0377	ENOG4105CVJ	phosphoglycerate mutase
Trad_0378	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Trad_0379	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Trad_0380	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Trad_0382	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Trad_0383	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Trad_0384	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Trad_0385	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Trad_0386	ENOG4105C7I	Dehydrogenase
Trad_0389	ENOG4106633	50S ribosomal protein l28
Trad_0390	ENOG4105CB5	ATP-dependent DNA helicase recG
Trad_0392	ENOG4105E0X	reductase
Trad_0395	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Trad_0400	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Trad_0401	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Trad_0403	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Trad_0404	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Trad_0405	ENOG4105DZP	Membrane-associated zinc metalloprotease
Trad_0406	ENOG4105CKK	Glycosyl transferase, family 2
Trad_0407	ENOG4105C5X	domain protein
Trad_0412	ENOG4108M1T	Cytochrome c-type biogenesis protein
Trad_0413	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Trad_0414	ENOG4105DA4	cytochrome c-type biogenesis protein
Trad_0415	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Trad_0419	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
Trad_0420	ENOG4107QIV	Cytochrome c biogenesis protein
Trad_0434	ENOG4105CHW	UPF0052 protein
Trad_0435	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Trad_0437	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Trad_0438	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Trad_0439	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Trad_0441	ENOG4105KG3	cytidine deaminase
Trad_0442	ENOG4107YR5	Diacylglycerol kinase
Trad_0443	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Trad_0444	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Trad_0445	ENOG4105C9A	Phoh family
Trad_0447	ENOG4105DI5	UPF0365 protein
Trad_0448	ENOG4105F7J	membrane-bound serine protease
Trad_0451	ENOG4105CMG	Carbohydrate kinase
Trad_0453	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
Trad_0454	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Trad_0456	ENOG4105DC7	peptidase M24
Trad_0457	ENOG4105CP7	Triose-phosphate isomerase
Trad_0459	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Trad_0460	ENOG4105C75	arginyL-tRNA synthetase
Trad_0463	ENOG4105CQB	FAD linked oxidase domain protein
Trad_0464	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_0466	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Trad_0467	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Trad_0474	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Trad_0479	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Trad_0480	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Trad_0481	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Trad_0483	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Trad_0485	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Trad_0491	ENOG4105W0E	50S ribosomal protein L33
Trad_0495	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Trad_0500	ENOG4105DE4	1-phosphofructokinase
Trad_0502	ENOG4105D44	asparaginase
Trad_0503	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Trad_0504	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Trad_0505	ENOG4105BZ1	(ABC) transporter
Trad_0506	ENOG4105BZ1	(ABC) transporter
Trad_0509	ENOG4105E2X	shikimate dehydrogenase
Trad_0511	ENOG4105DIN	metallophosphoesterase
Trad_0519	ENOG4108SHN	Glycosyl transferase, family 2
Trad_0527	ENOG4105VE1	Phosphatidylcholine synthase
Trad_0529	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Trad_0532	ENOG4105C59	p-type ATPase
Trad_0538	ENOG4108UVJ	appr-1-p processing domain protein
Trad_0539	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Trad_0548	ENOG4105D7V	transposase
Trad_0549	ENOG4105KQC	Competence protein
Trad_0550	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Trad_0551	ENOG4105D9P	serine threonine protein kinase
Trad_0554	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Trad_0555	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Trad_0558	ENOG4107Y9U	Membrane
Trad_0559	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
Trad_0560	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Trad_0562	ENOG4108UT2	hemolysin iii
Trad_0563	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
Trad_0565	ENOG4105EYW	Ion transport protein
Trad_0567	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
Trad_0568	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Trad_0569	ENOG4108IV0	ABC, transporter
Trad_0570	ENOG4105C0Z	ABC transporter
Trad_0572	ENOG4105C32	Amino acid ABC transporter (Permease)
Trad_0573	ENOG4105C32	Amino acid ABC transporter (Permease)
Trad_0574	ENOG4108IQE	Amp-dependent synthetase and ligase
Trad_0577	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Trad_0578	ENOG4105CJ1	ABC, transporter
Trad_0580	ENOG4105D94	Major Facilitator Superfamily
Trad_0581	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Trad_0582	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Trad_0583	ENOG4105C1Q	protoporphyrinogen oxidase
Trad_0584	ENOG4105C1J	atp-dependent rna helicase
Trad_0585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Trad_0587	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Trad_0588	ENOG4105BZ7	extracellular solute-binding protein family 1
Trad_0589	ENOG4107QPV	Serine Threonine protein kinase
Trad_0591	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Trad_0592	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Trad_0593	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Trad_0594	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Trad_0600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Trad_0602	ENOG4105UIB	(ABC) transporter
Trad_0604	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
Trad_0612	ENOG4105D7V	transposase
Trad_0614	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Trad_0615	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Trad_0618	ENOG4107T3P	ABC, transporter
Trad_0619	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Trad_0620	ENOG4105UQX	Mate efflux family protein
Trad_0621	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Trad_0622	ENOG4105CIY	formyltetrahydrofolate deformylase
Trad_0623	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Trad_0624	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Trad_0626	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
Trad_0630	ENOG4107QPH	glycogen) synthase
Trad_0634	ENOG4105D7V	transposase
Trad_0638	ENOG4105BZ1	(ABC) transporter
Trad_0640	ENOG4105CD3	dihydroorotase
Trad_0641	ENOG4105CXT	aspartate transcarbamylase
Trad_0642	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Trad_0644	ENOG4105E09	nadh pyrophosphatase
Trad_0645	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Trad_0647	ENOG4105X0R	protein from nitrogen regulatory protein P-II
Trad_0654	ENOG4105CHU	acetyl-coa acetyltransferase
Trad_0657	ENOG4105D2H	Uronic isomerase
Trad_0658	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Trad_0661	ENOG4105DMW	Dehydrogenase reductase
Trad_0665	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Trad_0666	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Trad_0667	ENOG4105CK5	oxidoreductase
Trad_0669	ENOG4105CEY	Amp-dependent synthetase and ligase
Trad_0671	ENOG4105EHG	Permease protein
Trad_0673	ENOG4105CVJ	phosphoglycerate mutase
Trad_0675	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Trad_0678	ENOG4105F9U	Dehydrogenase
Trad_0679	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
Trad_0680	ENOG4105DC7	peptidase M24
Trad_0682	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Trad_0683	ENOG4105ESV	Glycosyl transferase, family 4
Trad_0685	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Trad_0687	ENOG4105BZU	Histidine kinase
Trad_0690	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Trad_0691	ENOG4108S01	response regulator
Trad_0694	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Trad_0695	ENOG4105CNN	ABC, transporter
Trad_0699	ENOG4105CK5	oxidoreductase
Trad_0704	ENOG4105CJP	fad dependent oxidoreductase
Trad_0706	ENOG4108RVA	ribokinase
Trad_0707	ENOG41067S9	phage shock protein C, PspC
Trad_0712	ENOG4106855	Competence protein
Trad_0718	ENOG4105CNT	hydrolase family 2
Trad_0721	ENOG4105DRS	transport system, permease
Trad_0724	ENOG4108Z9Z	response to DNA damage stimulus
Trad_0731	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
Trad_0733	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
Trad_0734	ENOG4108KMV	Glycosyl transferase (Group 1
Trad_0735	ENOG4107TAE	Glycosyl transferase (Group 1
Trad_0736	ENOG4105CG5	Glycosyl transferase (Group 1
Trad_0740	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Trad_0742	ENOG4105BZN	citrate synthase
Trad_0743	ENOG4107PU6	Membrane
Trad_0746	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Trad_0747	ENOG4105CPP	Dehydrogenase, E1 component
Trad_0748	ENOG4105C7S	Dehydrogenase
Trad_0753	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_0754	ENOG4108Z4T	Peptidase M50
Trad_0756	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Trad_0757	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Trad_0758	ENOG4105CN9	Peptidase m42 family protein
Trad_0759	ENOG4105VRR	gCN5-related N-acetyltransferase
Trad_0760	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
Trad_0764	ENOG4105BZU	Histidine kinase
Trad_0768	ENOG4105DIK	(ABC) transporter
Trad_0769	ENOG4105CC5	ABC transporter
Trad_0773	ENOG4105BZ1	(ABC) transporter
Trad_0774	ENOG4105BZ1	(ABC) transporter
Trad_0779	ENOG41082HT	Binds the 23S rRNA (By similarity)
Trad_0781	ENOG4105D9N	nucleoside
Trad_0783	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Trad_0784	ENOG4105CAT	Cytidine monophosphate kinase
Trad_0785	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Trad_0786	ENOG4105BZU	Histidine kinase
Trad_0791	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Trad_0792	ENOG4105DU0	nucleoside hydrolase
Trad_0798	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Trad_0800	ENOG4105VPX	protein, conserved in bacteria
Trad_0808	ENOG4107R39	(ABC) transporter
Trad_0809	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Trad_0810	ENOG4106H78	methyltransferase
Trad_0812	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Trad_0814	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Trad_0817	ENOG4105DP4	dak2 domain fusion protein ylov
Trad_0821	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Trad_0822	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Trad_0823	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Trad_0825	ENOG4105CIG	ABC transporter
Trad_0828	ENOG4105C8P	)-transporter
Trad_0830	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Trad_0831	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Trad_0840	ENOG4105C26	Dehydrogenase
Trad_0845	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Trad_0846	ENOG4107YY3	extracellular solute-binding protein family 1
Trad_0848	ENOG4105FDT	acyl-CoA dehydrogenase
Trad_0852	ENOG4105CJW	magnesium transporter
Trad_0853	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Trad_0856	ENOG4107JIY	50S ribosomal protein l28
Trad_0858	ENOG4105FDK	ABC transporter
Trad_0859	ENOG4105CC5	ABC transporter
Trad_0863	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Trad_0864	ENOG4108Z03	MAF-like protein
Trad_0865	ENOG4108AH5	Binds directly to 16S ribosomal RNA (By similarity)
Trad_0868	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Trad_0869	ENOG4108VXD	carboxy-peptidase
Trad_0871	ENOG4105CA0	peroxidase
Trad_0880	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Trad_0881	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Trad_0886	ENOG4107ZT3	family UPF0126
Trad_0893	ENOG4105CK5	oxidoreductase
Trad_0895	ENOG4105CN9	Peptidase m42 family protein
Trad_0897	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Trad_0898	ENOG4105C7S	Dehydrogenase
Trad_0899	ENOG4107QN2	dihydrolipoyl dehydrogenase
Trad_0900	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Trad_0902	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Trad_0904	ENOG4107QHM	Sulfite reductase
Trad_0905	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Trad_0907	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
Trad_0908	ENOG4105DVY	radical SAM domain protein
Trad_0909	ENOG4108XHF	Pfam:DUF178
Trad_0911	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Trad_0912	ENOG4105C84	Histidine ammonia-lyase
Trad_0913	ENOG4105DWD	nucleoside recognition domain protein
Trad_0914	ENOG4105CI2	imidazolone-5-propionate hydrolase
Trad_0915	ENOG4105CYW	agmatinase
Trad_0916	ENOG4105CGP	Urocanate hydratase
Trad_0918	ENOG4105BZ8	glutamate synthase
Trad_0920	ENOG4107SJI	Dehydrogenase
Trad_0924	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Trad_0925	ENOG4107XKF	NMT1 THI5 Like Domain Protein
Trad_0926	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Trad_0927	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Trad_0941	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_0944	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Trad_0946	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_0947	ENOG4105WEM	extracellular solute-binding protein
Trad_0948	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Trad_0949	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Trad_0951	ENOG4105IRK	Glycosyl transferase (Group 1
Trad_0953	ENOG41081HM	2'-5' rna ligase
Trad_0962	ENOG4105NAE	bifunctional deaminase-reductase domain protein
Trad_0967	ENOG4108MCI	Transcriptional regulator, ARAC family
Trad_0969	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Trad_0970	ENOG4105C5F	glutamine synthetase
Trad_0972	ENOG4105C32	Amino acid ABC transporter (Permease)
Trad_0973	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Trad_0974	ENOG4105C0Z	ABC transporter
Trad_0975	ENOG4108IV0	ABC, transporter
Trad_0976	ENOG4108IXY	short-chain dehydrogenase reductase
Trad_0977	ENOG4105CFH	Aspartokinase
Trad_0978	ENOG410906A	Beta-Ig-H3 fasciclin
Trad_0982	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Trad_0983	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Trad_0984	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Trad_0988	ENOG4105C01	Dihydroxy-acid dehydratase
Trad_0989	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
Trad_0991	ENOG4105E98	transcriptional regulator DeoR family
Trad_0992	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Trad_0993	ENOG4105C2J	ABC transporter
Trad_0994	ENOG4105CNN	ABC, transporter
Trad_0995	ENOG4105CMG	Carbohydrate kinase
Trad_0999	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Trad_1001	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Trad_1002	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Trad_1004	ENOG4105C1V	Peptidase, M16
Trad_1005	ENOG4105C1V	Peptidase, M16
Trad_1011	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Trad_1012	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_1013	ENOG4105DA5	(ABC) transporter
Trad_1016	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
Trad_1018	ENOG4105D22	carbon starvation protein
Trad_1021	ENOG41067HZ	cytochrome C, class I
Trad_1026	ENOG4107SFQ	iron-sulfur binding
Trad_1028	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Trad_1030	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Trad_1033	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Trad_1034	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Trad_1035	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Trad_1036	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Trad_1037	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Trad_1038	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Trad_1039	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Trad_1040	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Trad_1041	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Trad_1042	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Trad_1043	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Trad_1044	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Trad_1045	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Trad_1046	ENOG4108CHD	50s ribosomal protein l29
Trad_1047	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Trad_1048	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Trad_1050	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Trad_1051	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Trad_1053	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Trad_1054	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Trad_1055	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Trad_1056	ENOG4105VPB	50S ribosomal protein L30
Trad_1057	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Trad_1058	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Trad_1059	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Trad_1060	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Trad_1061	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Trad_1062	ENOG41067V7	50S ribosomal protein L36
Trad_1063	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Trad_1064	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Trad_1065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Trad_1066	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Trad_1067	ENOG4108ZT0	50S ribosomal protein l17
Trad_1069	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Trad_1070	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_1071	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_1075	ENOG4108S01	response regulator
Trad_1076	ENOG4108Z6B	deaminase
Trad_1077	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Trad_1078	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Trad_1079	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Trad_1080	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Trad_1081	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Trad_1082	ENOG4105CXV	gliding motility protein
Trad_1084	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Trad_1085	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Trad_1086	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Trad_1087	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Trad_1088	ENOG4105DJV	ribulose-phosphate 3-epimerase
Trad_1090	ENOG4105KHC	sulfurtransferase
Trad_1092	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
Trad_1093	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
Trad_1097	ENOG4108JPW	Aminotransferase
Trad_1098	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Trad_1103	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Trad_1104	ENOG4107RH8	nuclease SbcCD subunit D
Trad_1105	ENOG4105EYH	Exonuclease
Trad_1108	ENOG4105C3M	thioredoxin reductase
Trad_1112	ENOG4105EAH	synthase
Trad_1114	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Trad_1115	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Trad_1116	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Trad_1117	ENOG4108ZSR	alkaline shock protein
Trad_1118	ENOG41082MB	Involved in the transcription termination process (By similarity)
Trad_1119	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Trad_1121	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Trad_1122	ENOG4105C88	aminopeptidase
Trad_1123	ENOG4108VUY	thioesterase Superfamily protein
Trad_1125	ENOG4107S5I	aldo keto reductase
Trad_1127	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_1128	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_1133	ENOG4105MGM	doxx family
Trad_1134	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
Trad_1135	ENOG4105DGU	Histone deacetylase
Trad_1140	ENOG4105D4B	ABC, transporter
Trad_1141	ENOG4105CNN	ABC, transporter
Trad_1142	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
Trad_1143	ENOG4105C2J	ABC transporter
Trad_1145	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Trad_1148	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
Trad_1150	ENOG4105C02	permease
Trad_1151	ENOG4105EHG	Permease protein
Trad_1152	ENOG4105DQ5	transport system permease protein
Trad_1153	ENOG4108MES	Periplasmic binding protein
Trad_1156	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Trad_1157	ENOG4105EHG	Permease protein
Trad_1158	ENOG4107R4I	Periplasmic binding protein
Trad_1162	ENOG4107Y03	Nitroreductase
Trad_1163	ENOG4108MES	Periplasmic binding protein
Trad_1165	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Trad_1168	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Trad_1182	ENOG4105D78	K07001 NTE family protein
Trad_1184	ENOG4105C0H	protease
Trad_1190	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Trad_1191	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Trad_1198	ENOG4105C0D	helicase
Trad_1200	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Trad_1202	ENOG4107FKK	extracellular solute-binding protein family 1
Trad_1204	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Trad_1207	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Trad_1209	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Trad_1214	ENOG4105E63	Pfam:DUF178
Trad_1215	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Trad_1216	ENOG410868C	50s ribosomal protein l35
Trad_1217	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Trad_1220	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Trad_1223	ENOG4105DCT	glycerol dehydrogenase
Trad_1226	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Trad_1227	ENOG4105C26	Dehydrogenase
Trad_1228	ENOG4105DH8	myo-inositol catabolism
Trad_1229	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
Trad_1232	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
Trad_1233	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Trad_1234	ENOG4105C2J	ABC transporter
Trad_1235	ENOG4108HWW	ABC transporter
Trad_1237	ENOG4105E98	transcriptional regulator DeoR family
Trad_1242	ENOG4105C5X	domain protein
Trad_1243	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
Trad_1245	ENOG4105DUM	transcriptional regulator, lysR family
Trad_1247	ENOG4105C2J	ABC transporter
Trad_1248	ENOG4107RNG	ABC transporter
Trad_1249	ENOG4105DFW	ABC transporter
Trad_1251	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
Trad_1257	ENOG410735N	
Trad_1258	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Trad_1259	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Trad_1260	ENOG4105CBG	Sulfatase
Trad_1262	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Trad_1263	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Trad_1264	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Trad_1265	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Trad_1266	ENOG4105C02	permease
Trad_1269	ENOG4105C02	permease
Trad_1270	ENOG4105D3Q	Sugar transferase
Trad_1273	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Trad_1275	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Trad_1282	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Trad_1283	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Trad_1285	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Trad_1286	ENOG4108UJD	30S ribosomal protein S9
Trad_1287	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Trad_1290	ENOG4105IJJ	transcriptional regulator, crp fnr family
Trad_1291	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Trad_1292	ENOG4105DEF	Extracellular solute-binding protein, family 5
Trad_1293	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_1294	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_1295	ENOG4105CQB	FAD linked oxidase domain protein
Trad_1296	ENOG4105CE4	GlcNAc 6-P deacetylase
Trad_1299	ENOG4105C5H	ABC transporter
Trad_1308	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Trad_1313	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Trad_1316	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_1317	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_1318	ENOG4105DEF	Extracellular solute-binding protein, family 5
Trad_1319	ENOG4105DC7	peptidase M24
Trad_1322	ENOG4107SET	aldo keto reductase
Trad_1323	ENOG4105CJ1	ABC, transporter
Trad_1326	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Trad_1327	ENOG4105D49	3-dehydroquinate synthase
Trad_1328	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Trad_1329	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Trad_1330	ENOG4105GVR	general secretion pathway protein D
Trad_1336	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Trad_1337	ENOG4105CDU	Replicative dna helicase
Trad_1338	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Trad_1339	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Trad_1343	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Trad_1345	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Trad_1347	ENOG4105CHV	Transcription elongation factor NusA
Trad_1348	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
Trad_1349	ENOG4105C5R	Aminotransferase
Trad_1352	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Trad_1353	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Trad_1354	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Trad_1355	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Trad_1359	ENOG4105CN1	protease
Trad_1360	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Trad_1364	ENOG4105DKQ	ROK family
Trad_1369	ENOG4105CGU	Enoyl-CoA hydratase
Trad_1371	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Trad_1373	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Trad_1374	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Trad_1377	ENOG4105CDY	transcriptional regulatory protein
Trad_1380	ENOG41074B2	UPF0747 protein
Trad_1381	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Trad_1383	ENOG41086Q6	ribosome-binding factor A
Trad_1388	ENOG4108JZA	Homocitrate synthase
Trad_1389	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Trad_1390	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Trad_1391	ENOG4106928	lysine biosynthesis protein LysW
Trad_1392	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Trad_1395	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Trad_1396	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Trad_1399	ENOG4107U4Q	acetylglutamate kinase
Trad_1400	ENOG4105M6F	mutator MutT protein
Trad_1401	ENOG4105C8Y	Acetylornithine aminotransferase
Trad_1402	ENOG4105RYD	Toxic component of a toxin-antitoxin (TA) module. A
Trad_1404	ENOG4107SBK	Acetylornithine deacetylase
Trad_1405	ENOG4105CBD	Diacylglycerol kinase
Trad_1406	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Trad_1407	ENOG4105CHR	reductase
Trad_1408	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Trad_1409	ENOG4105KNI	merR family transcriptional Regulator
Trad_1410	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Trad_1411	ENOG4105CYW	agmatinase
Trad_1414	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Trad_1420	ENOG4105CG3	alpha amylase, catalytic region
Trad_1421	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Trad_1432	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Trad_1435	ENOG4105FE9	pseudouridine synthase
Trad_1436	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Trad_1437	ENOG4105DR5	peptidase
Trad_1441	ENOG4106R7G	Glycoside hydrolase family 5
Trad_1442	ENOG4105CG3	alpha amylase, catalytic region
Trad_1445	ENOG4105DRS	transport system, permease
Trad_1453	ENOG4105C31	Tryptophanyl-tRNA synthetase
Trad_1456	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Trad_1458	ENOG4108M8H	domain protein
Trad_1459	ENOG4107QN2	dihydrolipoyl dehydrogenase
Trad_1462	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Trad_1463	ENOG4105EEI	dihydropteroate synthase
Trad_1468	ENOG4105ZU5	s-layer protein
Trad_1470	ENOG4105D1H	recombination factor protein RarA
Trad_1471	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Trad_1474	ENOG4105DKQ	ROK family
Trad_1476	ENOG4105BZU	Histidine kinase
Trad_1478	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Trad_1483	ENOG4105DSU	hydrolase
Trad_1486	ENOG4108HWW	ABC transporter
Trad_1487	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_1489	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Trad_1491	ENOG4105ENE	Histidine kinase
Trad_1492	ENOG4105WH1	Two component transcriptional regulator luxr family
Trad_1495	ENOG4105NAA	Cytochrome C oxidase, subunit II
Trad_1496	ENOG4107RQ2	Cytochrome c oxidase, subunit I
Trad_1498	ENOG4105C5I	Dehydrogenase
Trad_1500	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Trad_1503	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
Trad_1504	ENOG4105VT2	5-hydroxyisourate hydrolase
Trad_1506	ENOG4105S0E	allantoin catabolism protein
Trad_1511	ENOG4105C7W	Xanthine dehydrogenase
Trad_1513	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Trad_1515	ENOG4108DT4	serine threonine protein kinase
Trad_1524	ENOG4105BZU	Histidine kinase
Trad_1525	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Trad_1526	ENOG4105E7W	lamb ycsf family protein
Trad_1527	ENOG4105P4J	Allophanate hydrolase, subunit 1
Trad_1530	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Trad_1531	ENOG4105DRS	transport system, permease
Trad_1533	ENOG4108IJ6	ABC transporter
Trad_1538	ENOG4105C26	Dehydrogenase
Trad_1540	ENOG4107QP3	malate synthase g
Trad_1544	ENOG4105WH1	Two component transcriptional regulator luxr family
Trad_1546	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Trad_1554	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Trad_1555	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Trad_1556	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Trad_1560	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Trad_1563	ENOG4108S01	response regulator
Trad_1566	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_1567	ENOG4107R13	MMPL domain protein
Trad_1568	ENOG4105CQB	FAD linked oxidase domain protein
Trad_1569	ENOG4105EU8	FAD linked oxidase domain protein
Trad_1570	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Trad_1571	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
Trad_1572	ENOG4108IJ8	ABC transporter
Trad_1573	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
Trad_1574	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
Trad_1576	ENOG4105CPF	Cell wall formation (By similarity)
Trad_1579	ENOG4105WMR	Protein CrcB homolog
Trad_1580	ENOG41083TI	Protein CrcB homolog
Trad_1586	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Trad_1587	ENOG4105C25	Primosomal protein n'
Trad_1588	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Trad_1589	ENOG41062D9	Histidine kinase
Trad_1591	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Trad_1596	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Trad_1597	ENOG4105DIH	basic membrane
Trad_1598	ENOG4108V6E	Cell division protein mraZ
Trad_1599	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Trad_1601	ENOG4105CJN	penicillin-binding protein
Trad_1603	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Trad_1604	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Trad_1605	ENOG4105CNI	cell division protein FtsW
Trad_1606	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Trad_1607	ENOG4105DFU	Cell wall formation (By similarity)
Trad_1608	ENOG4107QWW	Cell wall formation (By similarity)
Trad_1610	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Trad_1611	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Trad_1612	ENOG4108YZ4	nudix hydrolase
Trad_1613	ENOG4105DTN	riboflavin biosynthesis protein ribF
Trad_1614	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Trad_1615	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Trad_1616	ENOG4107XU6	Glycosyl transferase (Group 1
Trad_1618	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Trad_1619	ENOG4105CS9	pantothenic acid kinase
Trad_1621	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Trad_1622	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Trad_1623	ENOG4105CN5	Metallo-Beta-Lactamase
Trad_1625	ENOG4105CPC	Aldo Keto reductase
Trad_1626	ENOG4105CPC	Aldo Keto reductase
Trad_1630	ENOG41081VB	Hydrolase
Trad_1635	ENOG4107QI1	Mate efflux family protein
Trad_1636	ENOG4105CGZ	zinc metallopeptidase
Trad_1637	ENOG4105CKB	glycosidase
Trad_1638	ENOG4105C22	threonyL-tRNA synthetase
Trad_1647	ENOG4105C8N	cysteinyl-tRNA synthetase
Trad_1648	ENOG4105C79	DNA protecting protein DprA
Trad_1649	ENOG4107R28	alpha amylase, catalytic region
Trad_1650	ENOG4106IPI	cyclase, family
Trad_1653	ENOG4108Z4U	Ferredoxin
Trad_1660	ENOG4105FB9	CRISPR-associated protein
Trad_1672	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Trad_1673	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Trad_1675	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Trad_1680	ENOG4105KJM	monovalent cation h antiporter subunit g
Trad_1682	ENOG4105D65	subunit l
Trad_1683	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Trad_1684	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_1689	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Trad_1690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Trad_1691	ENOG4105E39	Enoyl-CoA hydratase
Trad_1694	ENOG4106HB6	Alpha beta hydrolase
Trad_1695	ENOG4108JQ9	ABC transporter
Trad_1696	ENOG4105UIB	(ABC) transporter
Trad_1699	ENOG4105CPN	adenine deaminase
Trad_1700	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Trad_1701	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Trad_1702	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Trad_1704	ENOG4105C8B	TIGR00159 family
Trad_1709	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Trad_1713	ENOG4105DET	Rhamnulokinase
Trad_1714	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Trad_1716	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Trad_1718	ENOG4105DEF	Extracellular solute-binding protein, family 5
Trad_1719	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_1720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_1721	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Trad_1723	ENOG4105C1G	acyl-Coa dehydrogenase
Trad_1724	ENOG4105KHN	chorismate mutase
Trad_1731	ENOG4105DRS	transport system, permease
Trad_1732	ENOG4105ERH	Fumarylacetoacetate hydrolase
Trad_1735	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Trad_1737	ENOG4108IJ7	Glycine betaine
Trad_1738	ENOG4108HQS	Glycine betaine
Trad_1745	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Trad_1749	ENOG4105KJM	monovalent cation h antiporter subunit g
Trad_1752	ENOG4105CDH	Citrulline--aspartate ligase
Trad_1756	ENOG4105CH7	arginosuccinase
Trad_1758	ENOG4105BZU	Histidine kinase
Trad_1759	ENOG4105HDK	L-asparaginase
Trad_1764	ENOG4105II7	pyrroline-5-carboxylate reductase
Trad_1766	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Trad_1769	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Trad_1771	ENOG4105CUT	histidyl-tRNA synthetase
Trad_1772	ENOG4105C9M	aspartyl-trna synthetase
Trad_1774	ENOG4105C5S	asparaginyl-tRNA synthetase
Trad_1779	ENOG4105C5H	ABC transporter
Trad_1793	ENOG41080XP	Cbs domain
Trad_1799	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Trad_1800	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Trad_1801	ENOG4107T3P	ABC, transporter
Trad_1802	ENOG4105C3J	Cysteine desulfurase
Trad_1811	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Trad_1817	ENOG4107QRG	dna polymerase iii
Trad_1821	ENOG4105D7K	pfkb domain protein
Trad_1827	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_1828	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Trad_1831	ENOG4105CBX	hi0933 family
Trad_1832	ENOG4105CPC	Aldo Keto reductase
Trad_1841	ENOG4105DDC	Oxidoreductase domain protein
Trad_1842	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Trad_1846	ENOG4107TYG	Oxidoreductase domain-containing protein
Trad_1849	ENOG4108JQ7	(ABC) transporter
Trad_1851	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_1852	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
Trad_1853	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
Trad_1854	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Trad_1855	ENOG4105CPK	Glycosyl transferase (Group 1
Trad_1860	ENOG4105C9Q	fumarate hydratase class II
Trad_1866	ENOG4105C87	Aminotransferase class I and II
Trad_1867	ENOG4105E50	uracil-dna glycosylase
Trad_1868	ENOG4105D7W	serine acetyltransferase
Trad_1869	ENOG4105DR4	Methyltransferase
Trad_1870	ENOG4105E5G	Alpha beta hydrolase fold
Trad_1872	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Trad_1873	ENOG4105D49	3-dehydroquinate synthase
Trad_1878	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Trad_1879	ENOG4105Y3U	Transglycosylase-associated protein
Trad_1880	ENOG41062BK	proline dehydrogenase
Trad_1881	ENOG4105C26	Dehydrogenase
Trad_1883	ENOG4108IV0	ABC, transporter
Trad_1884	ENOG4105C0Z	ABC transporter
Trad_1888	ENOG4105EFA	4-hydroxyphenylacetate
Trad_1890	ENOG4105C26	Dehydrogenase
Trad_1893	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Trad_1894	ENOG4107YAU	phenylacetic acid degradation protein
Trad_1895	ENOG4105DZS	Phenylacetate-CoA ligase
Trad_1898	ENOG4105DXM	phenylacetic acid degradation protein
Trad_1900	ENOG41067HZ	cytochrome C, class I
Trad_1901	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Trad_1902	ENOG4105E2Z	phosphate ABC transporter (Permease
Trad_1903	ENOG4105C8U	phosphate abc transporter
Trad_1904	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Trad_1907	ENOG4105S7S	phosphonate abc transporter
Trad_1908	ENOG4105D5T	phosphonate abc transporter
Trad_1911	ENOG4105D5T	phosphonate abc transporter
Trad_1917	ENOG4105C6K	Malic enzyme
Trad_1920	ENOG4107QI1	Mate efflux family protein
Trad_1922	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Trad_1924	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Trad_1926	ENOG4105D60	lipoprotein releasing system transmembrane protein
Trad_1930	ENOG4105KA0	thioesterase Superfamily protein
Trad_1931	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Trad_1934	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Trad_1935	ENOG4105CH5	extracellular solute-binding protein, family 7
Trad_1936	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Trad_1937	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Trad_1938	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Trad_1944	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Trad_1945	ENOG4108I5C	dEAD DEAH box helicase
Trad_1946	ENOG41076QQ	Glycosyl transferase, family 2
Trad_1953	ENOG4105C02	permease
Trad_1954	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Trad_1955	ENOG4105DBI	uridine monophosphokinase
Trad_1959	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
Trad_1961	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Trad_1962	ENOG4107SET	aldo keto reductase
Trad_1963	ENOG4105CTQ	phosphohexokinase
Trad_1968	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Trad_1970	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Trad_1972	ENOG4107T5V	SNARE associated Golgi
Trad_1974	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Trad_1977	ENOG4105DRS	transport system, permease
Trad_1979	ENOG4105F8D	glycoside hydrolase family 4
Trad_1980	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_1981	ENOG4105DGW	oligopeptidase A
Trad_1982	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Trad_1984	ENOG4105CHU	acetyl-coa acetyltransferase
Trad_1985	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Trad_1986	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Trad_1987	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
Trad_1991	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Trad_1992	ENOG4105M08	Membrane
Trad_1993	ENOG4108N8X	transition metal ion binding
Trad_1999	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Trad_2000	ENOG4105DTD	Dehydrogenase
Trad_2003	ENOG4108K5P	(LipO)protein
Trad_2004	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Trad_2008	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Trad_2009	ENOG4108YXG	UPF0502 protein
Trad_2010	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Trad_2012	ENOG4105CDA	abc transporter atp-binding protein
Trad_2013	ENOG4105DRP	amino acid AbC transporter
Trad_2014	ENOG4105EZ7	amino acid ABC transporter
Trad_2015	ENOG4107QXX	ABC transporter
Trad_2016	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Trad_2017	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Trad_2018	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Trad_2020	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Trad_2023	ENOG4105EBX	v-type atpase
Trad_2025	ENOG4105D9P	serine threonine protein kinase
Trad_2029	ENOG4105M6F	mutator MutT protein
Trad_2030	ENOG4105DXN	mazG family
Trad_2031	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Trad_2035	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Trad_2036	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_2037	ENOG4105C4C	beta-galactosidase
Trad_2041	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Trad_2051	ENOG4105D8X	mechanosensitive ion channel
Trad_2052	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Trad_2053	ENOG4105C34	Pseudouridine synthase
Trad_2055	ENOG4105E2K	Glycosyl transferase (Group 1
Trad_2056	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Trad_2061	ENOG41061AU	MarR family Transcriptional regulator
Trad_2065	ENOG4105BZU	Histidine kinase
Trad_2067	ENOG4108N5B	2-phosphosulfolactate phosphatase
Trad_2069	ENOG4105K8R	UPF0145 protein
Trad_2070	ENOG4105C5S	asparaginyl-tRNA synthetase
Trad_2071	ENOG4107T8J	thymidine kinase
Trad_2073	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Trad_2074	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Trad_2075	ENOG4105CI3	gtp-binding protein typa
Trad_2078	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Trad_2085	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Trad_2086	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Trad_2088	ENOG4105VEQ	Cold shock protein
Trad_2091	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Trad_2096	ENOG4105DSG	hydrolase family 43
Trad_2100	ENOG4105DRS	transport system, permease
Trad_2105	ENOG4105F0N	pyrophosphate phospho-hydrolase
Trad_2106	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Trad_2107	ENOG4105KXX	peptidase s58 dmpa
Trad_2108	ENOG4108JQC	penicillin-binding protein 1A
Trad_2112	ENOG4105NWF	RbsD or FucU transport
Trad_2115	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Trad_2118	ENOG4107QN2	dihydrolipoyl dehydrogenase
Trad_2119	ENOG4105PMW	Domain of unknown function (DUF1990)
Trad_2121	ENOG4105C8T	Leucyl-tRNA synthetase
Trad_2125	ENOG4105VEQ	Cold shock protein
Trad_2126	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Trad_2127	ENOG4105CZX	twitching motility protein
Trad_2129	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Trad_2130	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Trad_2135	ENOG4108HNZ	carboxyl transferase
Trad_2138	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Trad_2139	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Trad_2142	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
Trad_2148	ENOG4105CEV	competence damage-inducible protein
Trad_2149	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Trad_2150	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Trad_2151	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Trad_2152	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Trad_2153	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Trad_2154	ENOG4108UXE	Protein tyrosine phosphatase
Trad_2155	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Trad_2156	ENOG4108UXE	Protein tyrosine phosphatase
Trad_2161	ENOG4105D74	hydrolase
Trad_2165	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Trad_2167	ENOG4105CHR	reductase
Trad_2168	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Trad_2169	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Trad_2170	ENOG4105KHC	sulfurtransferase
Trad_2174	ENOG4105C4K	Nad synthetase
Trad_2176	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Trad_2180	ENOG4108IUZ	ABC transporter
Trad_2181	ENOG4105CPQ	Dehydrogenase
Trad_2182	ENOG4107FKK	extracellular solute-binding protein family 1
Trad_2185	ENOG4105CHR	reductase
Trad_2186	ENOG4105CPQ	Dehydrogenase
Trad_2187	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Trad_2188	ENOG4107QSN	dihydrolipoamide acetyltransferase
Trad_2194	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Trad_2195	ENOG4107SCK	Monooxygenase
Trad_2198	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Trad_2205	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Trad_2206	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Trad_2208	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Trad_2210	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Trad_2213	ENOG4107S8C	mandelate racemase muconate lactonizing
Trad_2214	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Trad_2215	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Trad_2217	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Trad_2218	ENOG4105CTP	PilT protein domain protein
Trad_2220	ENOG4105D7V	transposase
Trad_2223	ENOG4107QP8	phosphohexose isomerase
Trad_2224	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Trad_2230	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Trad_2232	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Trad_2246	ENOG4108115	UPF0145 protein
Trad_2248	ENOG4105FE1	phytoene synthase
Trad_2249	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Trad_2250	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Trad_2251	ENOG4108Z0Z	intracellular protease Pfpi family
Trad_2255	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
Trad_2256	ENOG4105D7T	ABC transporter
Trad_2260	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Trad_2261	ENOG4105D1F	ATP-binding protein
Trad_2263	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Trad_2267	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Trad_2268	ENOG4108ZAF	Molybdopterin
Trad_2270	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Trad_2273	ENOG4108JQ9	ABC transporter
Trad_2274	ENOG4105BZP	glycoside hydrolase 15-related
Trad_2277	ENOG4105DWV	Homoserine O-trans-acetylase
Trad_2278	ENOG4108IQK	o-acetylhomoserine
Trad_2279	ENOG4108IQK	o-acetylhomoserine
Trad_2280	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Trad_2284	ENOG4108IGT	Dipeptidase
Trad_2285	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Trad_2287	ENOG4107QRA	Extracellular solute-binding protein, family 5
Trad_2289	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_2290	ENOG4105C3U	ABC transporter
Trad_2293	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Trad_2294	ENOG4105CNN	ABC, transporter
Trad_2295	ENOG4105C2J	ABC transporter
Trad_2297	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Trad_2298	ENOG4105E0S	extracellular solute-binding protein family 1
Trad_2299	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
Trad_2304	ENOG4105PWE	CRISPR-associated protein cas2
Trad_2307	ENOG4108VWQ	crispr-associated protein
Trad_2308	ENOG41060M0	Crispr-associated protein, cse4 family
Trad_2314	ENOG4105DR5	peptidase
Trad_2315	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Trad_2316	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Trad_2317	ENOG4107U9T	Pfam:Ribonuclease_BN
Trad_2318	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Trad_2319	ENOG4105BZA	Phosphoglycerate kinase
Trad_2320	ENOG4105JHR	Alginate biosynthesis protein AlgX
Trad_2322	ENOG4105C1G	acyl-Coa dehydrogenase
Trad_2324	ENOG4105C1G	acyl-Coa dehydrogenase
Trad_2329	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Trad_2330	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Trad_2331	ENOG4105K6T	rare lipoprotein A
Trad_2333	ENOG4105F8V	Hydrolase, tatD family
Trad_2338	ENOG4107QHF	type ii secretion system protein e
Trad_2339	ENOG4105CZX	twitching motility protein
Trad_2342	ENOG4105DMF	Dehydrogenase
Trad_2343	ENOG4108IUW	ABC transporter
Trad_2344	ENOG4108SDH	ABC, transporter
Trad_2345	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Trad_2349	ENOG4105BZ1	(ABC) transporter
Trad_2350	ENOG4105BZ1	(ABC) transporter
Trad_2353	ENOG4105C0B	DNA polymerase III (alpha subunit)
Trad_2355	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Trad_2356	ENOG4108IV0	ABC, transporter
Trad_2357	ENOG4105CP9	extracellular ligand-binding receptor
Trad_2358	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Trad_2359	ENOG4105C32	Amino acid ABC transporter (Permease)
Trad_2360	ENOG4108IQE	Amp-dependent synthetase and ligase
Trad_2361	ENOG4105C0Z	ABC transporter
Trad_2365	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
Trad_2366	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Trad_2367	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Trad_2368	ENOG4105C2M	dna polymerase I
Trad_2369	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Trad_2370	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Trad_2373	ENOG4105C6E	dna polymerase iii
Trad_2375	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Trad_2376	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Trad_2379	ENOG4105CAK	Cell division ATP-binding protein ftsE
Trad_2380	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Trad_2381	ENOG4108R5T	secreted protein
Trad_2382	ENOG4109015	Biopolymer transport protein exbD tolR
Trad_2384	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Trad_2385	ENOG4105D48	metallophosphoesterase
Trad_2387	ENOG4105BZU	Histidine kinase
Trad_2393	ENOG4108VX5	3-methyladenine DNA glycosylase
Trad_2395	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Trad_2399	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Trad_2402	ENOG4105CBD	Diacylglycerol kinase
Trad_2407	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Trad_2408	ENOG41062IR	nudix hydrolase
Trad_2409	ENOG4108J2R	molybdopterin oxidoreductase
Trad_2413	ENOG4105CPC	Aldo Keto reductase
Trad_2417	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_2418	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_2419	ENOG4105FGV	Chromate
Trad_2420	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Trad_2421	ENOG4105CUB	amino acid
Trad_2422	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Trad_2427	ENOG4105DZS	Phenylacetate-CoA ligase
Trad_2428	ENOG4108JT6	LycopEne
Trad_2430	ENOG4108I5G	Major Facilitator superfamily
Trad_2433	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Trad_2435	ENOG4106PMH	Extracellular solute-binding protein family 3
Trad_2436	ENOG4105E5Q	amino acid AbC transporter
Trad_2439	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Trad_2442	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
Trad_2443	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Trad_2447	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Trad_2449	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
Trad_2450	ENOG4105C8V	SAICAR synthetase
Trad_2452	ENOG4105C83	adenylosuccinate lyase
Trad_2455	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Trad_2463	ENOG4105CSR	polyphosphate kinase 2
Trad_2466	ENOG4108HM4	ABC transporter
Trad_2467	ENOG4105D38	putrescine abc transporter
Trad_2468	ENOG4105F38	ABC transporter, permease
Trad_2469	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Trad_2475	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Trad_2476	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Trad_2477	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Trad_2478	ENOG4108VZM	50s ribosomal protein L10
Trad_2479	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Trad_2480	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Trad_2481	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Trad_2482	ENOG410683Z	Preprotein translocase SecE subunit
Trad_2483	ENOG4105WDJ	50S ribosomal protein L33
Trad_2484	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Trad_2485	ENOG4105DCG	PHP domain protein
Trad_2487	ENOG4105DHP	deoxycytidine triphosphate deaminase
Trad_2488	ENOG41065SU	Two-component system sensor kinase
Trad_2489	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Trad_2493	ENOG4105CND	Glycosyl transferase, family 2
Trad_2498	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Trad_2499	ENOG4105DCF	alanine dehydrogenase
Trad_2501	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Trad_2502	ENOG4105C98	muts2 protein
Trad_2507	ENOG4108URH	decarboxylase
Trad_2509	ENOG4105BZU	Histidine kinase
Trad_2516	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Trad_2519	ENOG4105C3R	Methionine synthase
Trad_2524	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Trad_2528	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Trad_2529	ENOG4105CHR	reductase
Trad_2531	ENOG4107SET	aldo keto reductase
Trad_2536	ENOG4106YGA	NADH dehydrogenase (quinone)
Trad_2540	ENOG4105BZ1	(ABC) transporter
Trad_2541	ENOG4108Z9K	Osmotically inducible protein
Trad_2543	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Trad_2546	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Trad_2550	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Trad_2551	ENOG4105D98	threonine synthase
Trad_2552	ENOG4105D6E	homoserine dehydrogenase
Trad_2555	ENOG4105C3G	gtp-binding protein
Trad_2556	ENOG4108W63	CRP FNR family transcriptional regulator
Trad_2557	ENOG4107ZYJ	bioY protein
Trad_2560	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Trad_2562	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Trad_2563	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Trad_2564	ENOG4107WSY	Domain of unknown function DUF20
Trad_2565	ENOG4105CIF	Ornithine Cyclodeaminase
Trad_2567	ENOG4105CHM	Aminotransferase
Trad_2571	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Trad_2573	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Trad_2575	ENOG4105CMR	udp-glucose 4-epimerase
Trad_2576	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Trad_2582	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
Trad_2584	ENOG4105CHR	reductase
Trad_2585	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Trad_2586	ENOG4105DEF	Extracellular solute-binding protein, family 5
Trad_2588	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_2590	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Trad_2591	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Trad_2592	ENOG4108V0P	LemA family
Trad_2593	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Trad_2595	ENOG4105CBT	Fructose-1,6-bisphosphatase
Trad_2596	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Trad_2598	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Trad_2599	ENOG4105C12	Phosphoribosylglycinamide synthetase
Trad_2602	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Trad_2603	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Trad_2604	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Trad_2606	ENOG4105ES5	Histidine kinase
Trad_2607	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Trad_2608	ENOG4105MA4	psp1 domain protein
Trad_2611	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Trad_2619	ENOG4105DRS	transport system, permease
Trad_2621	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
Trad_2622	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Trad_2623	ENOG4105CD5	CoA-binding domain protein
Trad_2626	ENOG4105BZU	Histidine kinase
Trad_2629	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Trad_2634	ENOG4105CGD	Nad-dependent epimerase dehydratase
Trad_2635	ENOG4105EAH	synthase
Trad_2646	ENOG4105DTQ	mandelate racemase muconate lactonizing
Trad_2649	ENOG4107XWI	flavin reductase domain protein, FMN-binding
Trad_2651	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
Trad_2652	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Trad_2658	ENOG4105C4Y	ABC transporter
Trad_2660	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Trad_2661	ENOG4105DFA	alanine racemase domain protein
Trad_2663	ENOG41090K0	Transcriptional regulator, Crp Fnr family
Trad_2665	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Trad_2668	ENOG4105WH1	Two component transcriptional regulator luxr family
Trad_2669	ENOG4105C4X	radical SAM domain protein
Trad_2673	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
Trad_2674	ENOG4105KJM	monovalent cation h antiporter subunit g
Trad_2675	ENOG41080TA	Multiple resistance and ph regulation protein f
Trad_2676	ENOG4105SC1	monovalent cation H antiporter subunit E
Trad_2677	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Trad_2678	ENOG4108ZE9	Monovalent cation H antiporter subunit C
Trad_2679	ENOG4105HC0	Na H antiporter
Trad_2680	ENOG4105D65	subunit l
Trad_2681	ENOG4105CTD	carboxy-peptidase
Trad_2682	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Trad_2687	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Trad_2692	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_2693	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_2694	ENOG4105DEF	Extracellular solute-binding protein, family 5
Trad_2695	ENOG4105CPC	Aldo Keto reductase
Trad_2697	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Trad_2698	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Trad_2703	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Trad_2704	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
Trad_2707	ENOG4105EMU	Dehydrogenase
Trad_2711	ENOG4105C0D	helicase
Trad_2718	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Trad_2730	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Trad_2732	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Trad_2735	ENOG4107YU2	histidine triad (hIT) protein
Trad_2736	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Trad_2737	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Trad_2748	ENOG4108ZMR	Ion transport 2 domain-containing protein
Trad_2752	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Trad_2754	ENOG4105F6E	Acyl-transferase
Trad_2755	ENOG4105K70	DNA-binding protein
Trad_2757	ENOG4105EJQ	L-serine dehydratase
Trad_2758	ENOG4105CEP	NADH dehydrogenase
Trad_2762	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
Trad_2764	ENOG4108Z86	Glutamine amidotransferase
Trad_2768	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Trad_2769	ENOG4105DIN	metallophosphoesterase
Trad_2771	ENOG4105CHU	acetyl-coa acetyltransferase
Trad_2773	ENOG4105BZU	Histidine kinase
Trad_2774	ENOG4105WS7	Cation transport regulator
Trad_2775	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Trad_2777	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Trad_2779	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Trad_2780	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Trad_2784	ENOG4105CE9	30S ribosomal protein S2
Trad_2785	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Trad_2786	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Trad_2787	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Trad_2788	ENOG4105KNE	Phosphatidate cytidylyltransferase
Trad_2790	ENOG41067VY	50S ribosomal protein L32
Trad_2791	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Trad_2792	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Trad_2793	ENOG4105CHR	reductase
Trad_2794	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Trad_2797	ENOG4105C6T	cysteine synthase
Trad_2799	ENOG4105EPR	degv family
Trad_2800	ENOG4105C0P	Mg chelatase subunit ChlI
Trad_2803	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Trad_2804	ENOG4105CCU	oxidase (Subunit III)
Trad_2805	ENOG41067HZ	cytochrome C, class I
Trad_2812	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Trad_2814	ENOG4107S1N	anthranilate phosphoribosyltransferase
Trad_2816	ENOG4105DDQ	anthranilate synthase
Trad_2818	ENOG4105CRQ	synthase (Component I)
Trad_2824	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Trad_2827	ENOG4105ZMH	deoxynucleoside kinase
Trad_2828	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Trad_2829	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
Trad_2830	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Trad_2840	ENOG4105D06	uba thif-type nad fad binding protein
Trad_2841	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Trad_2844	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Trad_2848	ENOG4105C7B	Threonine dehydratase
Trad_2850	ENOG4107QUY	Guanine deaminase
Trad_2851	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Trad_2852	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Trad_2856	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Trad_2859	ENOG4108TJN	glycosyl transferase group 1
Trad_2860	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Trad_2862	ENOG4105JNK	Glycosyl transferase (Group 1
Trad_2864	ENOG4105D3Q	Sugar transferase
Trad_2867	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Trad_2870	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Trad_2874	ENOG4105CNU	cell division protein FtsK
Trad_2875	ENOG4105C02	permease
Trad_2877	ENOG4105EG2	ABC transporter, permease
Trad_2878	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Trad_2880	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_2884	ENOG4105DGU	Histone deacetylase
Trad_2887	ENOG4105CPQ	Dehydrogenase
Trad_2888	ENOG4105CPQ	Dehydrogenase
Trad_2889	ENOG4105CHR	reductase
Trad_2890	ENOG4105ETE	Transcriptional regulator (LacI family
Trad_2894	ENOG4105CPQ	Dehydrogenase
Trad_2895	ENOG4105CPQ	Dehydrogenase
Trad_2896	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
Trad_2898	ENOG4105BZU	Histidine kinase
Trad_2905	ENOG4105CSM	endonuclease III
Trad_2910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Trad_2911	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Trad_2917	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Trad_2918	ENOG4105VN1	Heat shock protein
Trad_2920	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Trad_2928	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Trad_2929	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Trad_2932	ENOG4105CX6	glutaminyL-tRNA synthetase
Trad_2934	ENOG4105SFS	phosphoesterase RecJ domain protein
Trad_2935	ENOG4105BZU	Histidine kinase
Trad_2936	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Trad_2937	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Trad_2938	ENOG4105C9B	Cysteine desulfurase
Trad_2940	ENOG4105CV8	reductase
Trad_2949	ENOG4108IQE	Amp-dependent synthetase and ligase
Trad_2950	ENOG4105C1G	acyl-Coa dehydrogenase
Trad_2952	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Trad_2957	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Trad_2958	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Trad_2959	ENOG4105RTX	GreA GreB family elongation factor
Trad_2960	ENOG4105CRK	lysyL-tRNA synthetase
Trad_2962	ENOG4105CJR	Integral membrane protein (MviN
Trad_2964	ENOG41080R8	Conserved Protein
Trad_2965	ENOG4107QR9	Iron-sulfur cluster binding protein
Trad_2966	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Trad_2968	ENOG4105E98	transcriptional regulator DeoR family
Trad_2969	ENOG4105K63	Thioredoxin
Trad_2970	ENOG4105UQX	Mate efflux family protein
Trad_2971	ENOG4105CHM	Aminotransferase
Trad_2972	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Trad_2974	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_2975	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
Trad_2976	ENOG4105D65	subunit l
Trad_2977	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_2978	ENOG41087XN	oxidoreductase
Trad_2979	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_2980	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Trad_2981	ENOG4108IEH	NADH dehydrogenase subunit g
Trad_2982	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
Trad_2983	ENOG4105GKE	subunit e
Trad_2985	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_2986	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Trad_2987	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Trad_2988	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Trad_2989	ENOG4105G5W	regulator Fur family
Trad_2990	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Trad_2991	ENOG4105FA0	parb-like partition protein
Trad_2992	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Trad_2993	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Trad_2994	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Trad_R0039	ENOG4105CVP	deoxyribo-dipyrimidine photolyase