locus-tag	class	description
Trad_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Trad_0003	COG0148	phosphopyruvate hydratase activity
Trad_0005	COG0359	binds to the 23S rRNA
Trad_0006	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Trad_0007	COG0629	single-stranded DNA binding
Trad_0008	COG0360	Binds together with S18 to 16S ribosomal RNA
Trad_0011	COG0443	Heat shock 70 kDa protein
Trad_0013	COG0484	heat shock protein binding
Trad_0014	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Trad_0017	COG1331	Highly conserved protein containing a thioredoxin domain
Trad_0021	COG0335	large ribosomal subunit rRNA binding
Trad_0022	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Trad_0023	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Trad_0024	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Trad_0025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Trad_0029	COG0792	nuclease activity
Trad_0030	COG0135	phosphoribosylanthranilate isomerase activity
Trad_0031	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Trad_0034	COG2151	metal-sulfur cluster biosynthetic enzyme
Trad_0035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Trad_0036	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Trad_0041	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Trad_0042	COG0640	Transcriptional regulator
Trad_0045	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Trad_0046	COG2894	cell division
Trad_0047	COG0210	DNA helicase
Trad_0049	COG2389	metal-binding protein
Trad_0051	COG3842	ATPase activity
Trad_0057	COG1960	acyl-CoA dehydrogenase activity
Trad_0059	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Trad_0059	COG3153	acetyltransferase
Trad_0060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Trad_0060	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Trad_0061	COG2423	ornithine cyclodeaminase activity
Trad_0062	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Trad_0063	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Trad_0064	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Trad_0066	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Trad_0068	COG0336	Belongs to the RNA methyltransferase TrmD family
Trad_0069	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Trad_0071	COG0228	four-way junction DNA binding
Trad_0076	COG0138	bifunctional purine biosynthesis protein purh
Trad_0080	COG1166	arginine decarboxylase activity
Trad_0081	COG0598	Magnesium transport protein CorA
Trad_0082	COG0542	response to heat
Trad_0083	COG0107	imidazoleglycerol-phosphate synthase activity
Trad_0086	COG0626	cystathionine gamma-synthase activity
Trad_0091	COG1309	transcriptional regulator
Trad_0094	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Trad_0096	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Trad_0102	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Trad_0105	COG0523	cobalamin synthesis protein
Trad_0112	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Trad_0113	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Trad_0124	COG1176	ABC-type spermidine putrescine transport system, permease component I
Trad_0125	COG1177	transmembrane transport
Trad_0130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Trad_0132	COG0366	Alpha amylase catalytic
Trad_0132	COG1874	Beta-galactosidase
Trad_0133	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Trad_0134	COG0019	diaminopimelate decarboxylase activity
Trad_0135	COG0446	pyridine nucleotide-disulphide oxidoreductase
Trad_0137	COG1012	belongs to the aldehyde dehydrogenase family
Trad_0139	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Trad_0140	COG0546	phosphoglycolate phosphatase activity
Trad_0141	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Trad_0145	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_0147	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Trad_0150	COG3118	belongs to the thioredoxin family
Trad_0151	COG0402	S-adenosylhomocysteine deaminase activity
Trad_0154	COG4636	protein conserved in cyanobacteria
Trad_0155	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Trad_0157	COG0601	transmembrane transport
Trad_0158	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_0160	COG4608	Belongs to the ABC transporter superfamily
Trad_0162	COG1069	ribulokinase activity
Trad_0163	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Trad_0164	COG0456	acetyltransferase
Trad_0165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Trad_0168	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Trad_0173	COG0736	holo-[acyl-carrier-protein] synthase activity
Trad_0174	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Trad_0177	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Trad_0178	COG2086	electron transfer activity
Trad_0179	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Trad_0180	COG2181	nitrate reductase activity
Trad_0180	COG0247	lactate metabolic process
Trad_0181	COG1472	Belongs to the glycosyl hydrolase 3 family
Trad_0183	COG1482	cell wall glycoprotein biosynthetic process
Trad_0184	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Trad_0186	COG1132	(ABC) transporter
Trad_0190	COG3273	potassium ion transport
Trad_0190	COG0471	metal ion transport
Trad_0192	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Trad_0194	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Trad_0200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Trad_0201	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Trad_0202	COG2738	Putative neutral zinc metallopeptidase
Trad_0203	COG2359	stage V sporulation protein S
Trad_0204	COG0028	Belongs to the TPP enzyme family
Trad_0205	COG0440	acetolactate synthase activity
Trad_0206	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Trad_0207	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Trad_0208	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Trad_0209	COG0070	glutamate synthase
Trad_0209	COG0067	glutamate synthase
Trad_0209	COG0069	glutamate synthase activity
Trad_0212	COG1063	alcohol dehydrogenase
Trad_0215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Trad_0216	COG2197	response regulator
Trad_0218	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Trad_0219	COG3546	catalase activity
Trad_0221	COG0408	coproporphyrinogen oxidase activity
Trad_0222	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Trad_0223	COG0745	RESPONSE REGULATOR receiver
Trad_0225	COG0113	porphobilinogen synthase activity
Trad_0228	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Trad_0231	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Trad_0232	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Trad_0235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Trad_0237	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Trad_0239	COG1803	Methylglyoxal synthase
Trad_0240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Trad_0241	COG0569	domain protein
Trad_0242	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Trad_0244	COG0569	domain protein
Trad_0245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Trad_0246	COG2066	Belongs to the glutaminase family
Trad_0246	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Trad_0248	COG1404	Belongs to the peptidase S8 family
Trad_0250	COG2258	MOSC domain
Trad_0252	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Trad_0253	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Trad_0255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Trad_0257	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Trad_0259	COG3206	protein involved in exopolysaccharide biosynthesis
Trad_0261	COG0719	Fe-S assembly protein
Trad_0265	COG0396	ATPase activity
Trad_0266	COG2815	serine threonine protein kinase
Trad_0266	COG0515	serine threonine protein kinase
Trad_0267	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Trad_0268	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Trad_0268	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Trad_0271	COG1366	Belongs to the anti-sigma-factor antagonist family
Trad_0273	COG0514	ATP-dependent DNA helicase (RecQ)
Trad_0274	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Trad_0274	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Trad_0276	COG1115	amino acid carrier protein
Trad_0277	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Trad_0286	COG1999	signal sequence binding
Trad_0287	COG1090	epimerase
Trad_0289	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Trad_0291	COG1983	PspC domain protein
Trad_0292	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Trad_0293	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Trad_0297	COG1175	transmembrane transport
Trad_0300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Trad_0302	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Trad_0310	COG1132	(ABC) transporter
Trad_0312	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Trad_0313	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Trad_0315	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Trad_0316	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Trad_0320	COG0802	atpase or kinase
Trad_0323	COG0194	GDP metabolic process
Trad_0324	COG1758	RNA polymerase activity
Trad_0326	COG1438	arginine binding
Trad_0328	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Trad_0331	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Trad_0333	COG4712	double-strand break repair protein
Trad_0335	COG0181	hydroxymethylbilane synthase activity
Trad_0336	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Trad_0340	COG1733	regulation of RNA biosynthetic process
Trad_0341	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Trad_0343	COG0705	Rhomboid family
Trad_0343	COG0457	Tetratricopeptide repeat
Trad_0345	COG1120	ATPase activity
Trad_0350	COG0302	gtp cyclohydrolase
Trad_0352	COG0783	Belongs to the Dps family
Trad_0354	COG0561	phosphatase activity
Trad_0355	COG2009	succinate dehydrogenase
Trad_0357	COG1053	succinate dehydrogenase
Trad_0358	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Trad_0359	COG2239	Acts as a magnesium transporter
Trad_0363	COG1968	undecaprenyl-diphosphatase activity
Trad_0364	COG0251	oxidation-reduction process
Trad_0366	COG0154	amidase activity
Trad_0367	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Trad_0369	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Trad_0370	COG0706	membrane insertase activity
Trad_0373	COG0590	tRNA wobble adenosine to inosine editing
Trad_0375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Trad_0377	COG0406	alpha-ribazole phosphatase activity
Trad_0378	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Trad_0379	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Trad_0382	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Trad_0383	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Trad_0384	COG2890	protein-(glutamine-N5) methyltransferase activity
Trad_0385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Trad_0386	COG2902	Dehydrogenase
Trad_0387	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Trad_0389	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Trad_0390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Trad_0392	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Trad_0400	COG0517	IMP dehydrogenase activity
Trad_0400	COG0516	GMP reductase activity
Trad_0401	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Trad_0402	COG1994	Peptidase M50
Trad_0402	COG0517	IMP dehydrogenase activity
Trad_0403	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Trad_0404	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Trad_0405	COG0750	zinc metalloprotease
Trad_0406	COG0463	Glycosyl transferase, family 2
Trad_0407	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Trad_0413	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Trad_0415	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Trad_0419	COG4133	protoheme IX ABC transporter activity
Trad_0420	COG0785	Cytochrome C biogenesis protein
Trad_0428	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Trad_0434	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Trad_0435	COG1660	Displays ATPase and GTPase activities
Trad_0437	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Trad_0438	COG0131	Imidazoleglycerol-phosphate dehydratase
Trad_0439	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Trad_0441	COG0295	cytidine deaminase activity
Trad_0442	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Trad_0443	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Trad_0444	COG1480	7TM receptor with intracellular HD hydrolase
Trad_0445	COG1702	phosphate starvation-inducible protein PhoH
Trad_0447	COG4864	UPF0365 protein
Trad_0448	COG1030	water channel activity
Trad_0451	COG1070	Carbohydrate kinase
Trad_0453	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Trad_0454	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Trad_0456	COG0006	proline dipeptidase activity
Trad_0457	COG0149	triose-phosphate isomerase activity
Trad_0459	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Trad_0460	COG0018	arginyl-trna synthetase
Trad_0463	COG0247	lactate metabolic process
Trad_0463	COG0277	FAD linked oxidase domain protein
Trad_0466	COG1175	transmembrane transport
Trad_0467	COG0395	ABC-type sugar transport system, permease component
Trad_0470	COG0673	inositol 2-dehydrogenase activity
Trad_0474	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Trad_0479	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Trad_0480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Trad_0481	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Trad_0483	COG0557	exoribonuclease II activity
Trad_0485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Trad_0491	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Trad_0495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Trad_0500	COG1105	Belongs to the carbohydrate kinase PfkB family
Trad_0503	COG0850	regulation of cytokinetic process
Trad_0504	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Trad_0505	COG1132	(ABC) transporter
Trad_0509	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Trad_0511	COG1408	metallophosphoesterase
Trad_0519	COG1215	transferase activity, transferring glycosyl groups
Trad_0527	COG1183	phosphatidylcholine synthase activity
Trad_0529	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Trad_0530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Trad_0532	COG2217	Heavy metal translocating P-type atpase
Trad_0536	COG0604	alcohol dehydrogenase
Trad_0538	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Trad_0549	COG1555	photosystem II stabilization
Trad_0549	COG1596	polysaccharide export
Trad_0550	COG2333	competence protein COMEC
Trad_0550	COG0658	competence protein
Trad_0554	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Trad_0555	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Trad_0558	COG0697	spore germination
Trad_0559	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Trad_0560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Trad_0562	COG1272	protein, Hemolysin III
Trad_0563	COG3361	conserved protein (COG2071)
Trad_0565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_0567	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Trad_0568	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Trad_0572	COG0559	Belongs to the binding-protein-dependent transport system permease family
Trad_0573	COG0559	Belongs to the binding-protein-dependent transport system permease family
Trad_0574	COG1022	Amp-dependent synthetase and ligase
Trad_0577	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Trad_0578	COG1131	(ABC) transporter
Trad_0580	COG2814	Major facilitator Superfamily
Trad_0581	COG0746	molybdenum cofactor guanylyltransferase activity
Trad_0582	COG0412	Dienelactone hydrolase
Trad_0584	COG0513	Belongs to the DEAD box helicase family
Trad_0585	COG0745	RESPONSE REGULATOR receiver
Trad_0586	COG0395	ABC-type sugar transport system, permease component
Trad_0588	COG1653	transport
Trad_0589	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Trad_0589	COG0515	serine threonine protein kinase
Trad_0591	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Trad_0592	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Trad_0593	COG0740	serine-type endopeptidase activity
Trad_0594	COG0544	peptidyl-prolyl cis-trans isomerase activity
Trad_0600	COG0714	Associated with various cellular activities
Trad_0614	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Trad_0615	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_0618	COG1653	transport
Trad_0619	COG2255	four-way junction helicase activity
Trad_0620	COG0534	Mate efflux family protein
Trad_0621	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Trad_0622	COG0788	formyltetrahydrofolate deformylase activity
Trad_0623	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Trad_0624	COG0358	DNA primase activity
Trad_0626	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Trad_0630	COG0297	glycogen (starch) synthase activity
Trad_0638	COG1132	(ABC) transporter
Trad_0640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Trad_0641	COG0540	Belongs to the ATCase OTCase family
Trad_0642	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Trad_0644	COG2816	NAD+ diphosphatase activity
Trad_0645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Trad_0647	COG3870	Protein conserved in bacteria
Trad_0651	COG0616	signal peptide processing
Trad_0652	COG5001	Diguanylate cyclase
Trad_0654	COG0183	Belongs to the thiolase family
Trad_0657	COG1904	glucuronate isomerase
Trad_0658	COG3265	gluconokinase activity
Trad_0661	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_0665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Trad_0667	COG0673	inositol 2-dehydrogenase activity
Trad_0669	COG0318	PFAM AMP-dependent synthetase and ligase
Trad_0671	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Trad_0675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Trad_0678	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Trad_0679	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_0680	COG0006	proline dipeptidase activity
Trad_0682	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Trad_0683	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Trad_0684	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Trad_0685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Trad_0687	COG5002	protein histidine kinase activity
Trad_0690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Trad_0691	COG2197	response regulator
Trad_0692	COG0673	inositol 2-dehydrogenase activity
Trad_0694	COG1879	ABC-type sugar transport system periplasmic component
Trad_0695	COG1172	Belongs to the binding-protein-dependent transport system permease family
Trad_0699	COG0673	inositol 2-dehydrogenase activity
Trad_0704	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Trad_0706	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Trad_0707	COG1983	PspC domain protein
Trad_0712	COG4968	Prepilin-type N-terminal cleavage methylation domain
Trad_0718	COG3250	beta-galactosidase activity
Trad_0720	COG1175	transmembrane transport
Trad_0721	COG0395	ABC-type sugar transport system, permease component
Trad_0724	COG3685	Protein conserved in bacteria
Trad_0726	COG3546	catalase activity
Trad_0729	COG2197	response regulator
Trad_0731	COG0529	Catalyzes the synthesis of activated sulfate
Trad_0732	COG2046	Belongs to the sulfate adenylyltransferase family
Trad_0733	COG1218	3'(2'),5'-bisphosphate nucleotidase
Trad_0734	COG0438	transferase activity, transferring glycosyl groups
Trad_0735	COG0438	transferase activity, transferring glycosyl groups
Trad_0740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Trad_0741	COG4978	Transcriptional regulator
Trad_0741	COG0789	Transcriptional regulator
Trad_0742	COG0372	Belongs to the citrate synthase family
Trad_0743	COG3174	membrane
Trad_0746	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Trad_0747	COG0022	dehydrogenase e1 component
Trad_0748	COG0508	dehydrogenase complex catalyzes the overall conversion of
Trad_0753	COG0577	efflux transmembrane transporter activity
Trad_0753	COG1136	(ABC) transporter
Trad_0754	COG1994	Peptidase M50
Trad_0756	COG0617	tRNA 3'-terminal CCA addition
Trad_0757	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Trad_0758	COG1363	Peptidase, m42
Trad_0759	COG1247	-acetyltransferase
Trad_0760	COG0492	ferredoxin-NADP+ reductase activity
Trad_0761	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Trad_0768	COG1121	(ABC) transporter
Trad_0769	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Trad_0770	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_0773	COG1132	(ABC) transporter
Trad_0774	COG1132	(ABC) transporter
Trad_0779	COG0254	rRNA binding
Trad_0780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Trad_0781	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Trad_0783	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Trad_0784	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Trad_0785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Trad_0786	COG3706	GGDEF domain
Trad_0791	COG0745	RESPONSE REGULATOR receiver
Trad_0792	COG1957	nucleoside hydrolase
Trad_0798	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Trad_0800	COG1937	Protein conserved in bacteria
Trad_0808	COG1136	(ABC) transporter
Trad_0808	COG0577	efflux transmembrane transporter activity
Trad_0809	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Trad_0810	COG0742	ribosomal rna small subunit methyltransferase
Trad_0811	COG0477	Major facilitator Superfamily
Trad_0812	COG0653	protein targeting
Trad_0814	COG0284	orotidine-5'-phosphate decarboxylase activity
Trad_0817	COG1461	Dihydroxyacetone kinase
Trad_0821	COG0315	cyclic pyranopterin monophosphate synthase activity
Trad_0822	COG0101	tRNA pseudouridine synthase activity
Trad_0823	COG0671	phosphoesterase, PA-phosphatase related
Trad_0828	COG0471	metal ion transport
Trad_0830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Trad_0831	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Trad_0838	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Trad_0840	COG1012	belongs to the aldehyde dehydrogenase family
Trad_0845	COG1175	transmembrane transport
Trad_0846	COG1653	transport
Trad_0847	COG1231	oxidoreductase activity
Trad_0848	COG1960	acyl-CoA dehydrogenase activity
Trad_0851	COG1285	pathogenesis
Trad_0852	COG2239	Acts as a magnesium transporter
Trad_0853	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Trad_0856	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Trad_0858	COG1121	(ABC) transporter
Trad_0863	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Trad_0864	COG0424	maF-like protein
Trad_0865	COG0268	Binds directly to 16S ribosomal RNA
Trad_0867	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Trad_0868	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Trad_0869	COG1876	peptidase activity
Trad_0871	COG1858	cytochrome C peroxidase
Trad_0880	COG0704	Plays a role in the regulation of phosphate uptake
Trad_0881	COG0745	RESPONSE REGULATOR receiver
Trad_0886	COG2860	membrane
Trad_0893	COG0673	inositol 2-dehydrogenase activity
Trad_0897	COG0567	Dehydrogenase, E1 component
Trad_0898	COG0508	dehydrogenase complex catalyzes the overall conversion of
Trad_0899	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Trad_0900	COG0671	phosphoesterase, PA-phosphatase related
Trad_0902	COG1648	precorrin-2 dehydrogenase activity
Trad_0902	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Trad_0904	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Trad_0905	COG0175	sulfate reduction
Trad_0906	COG2133	pyrroloquinoline quinone binding
Trad_0907	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Trad_0908	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Trad_0909	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Trad_0911	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Trad_0912	COG2986	histidine ammonia-lyase
Trad_0914	COG1228	amidohydrolase
Trad_0915	COG0010	Belongs to the arginase family
Trad_0916	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Trad_0918	COG0493	'glutamate synthase
Trad_0924	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Trad_0925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Trad_0926	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_0927	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Trad_0941	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_0942	COG0601	transmembrane transport
Trad_0944	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_0945	COG1473	amidohydrolase
Trad_0946	COG1609	Transcriptional regulator
Trad_0947	COG1653	transport
Trad_0948	COG1175	transmembrane transport
Trad_0949	COG0395	ABC-type sugar transport system, permease component
Trad_0951	COG0438	transferase activity, transferring glycosyl groups
Trad_0953	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Trad_0962	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Trad_0967	COG1917	Cupin 2, conserved barrel domain protein
Trad_0967	COG2207	Transcriptional regulator
Trad_0969	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Trad_0970	COG0174	glutamine synthetase
Trad_0975	COG0410	ABC transporter
Trad_0976	COG0300	oxidoreductase activity
Trad_0977	COG0527	aspartate kinase activity
Trad_0978	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Trad_0982	COG0163	prenyltransferase activity
Trad_0983	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Trad_0984	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Trad_0988	COG0129	dihydroxy-acid dehydratase activity
Trad_0989	COG1085	galactose-1-phosphate uridylyltransferase
Trad_0991	COG1349	DNA-binding transcription factor activity
Trad_0992	COG1879	ABC-type sugar transport system periplasmic component
Trad_0994	COG1172	Belongs to the binding-protein-dependent transport system permease family
Trad_0995	COG1070	Carbohydrate kinase
Trad_0997	COG1070	Carbohydrate kinase
Trad_0999	COG2337	Toxic component of a toxin-antitoxin (TA) module
Trad_1001	COG1254	Belongs to the acylphosphatase family
Trad_1002	COG0134	indole-3-glycerol-phosphate synthase activity
Trad_1003	COG4221	oxidoreductase activity
Trad_1004	COG0612	Peptidase, M16
Trad_1005	COG0612	Peptidase, M16
Trad_1011	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Trad_1012	COG0577	efflux transmembrane transporter activity
Trad_1012	COG1136	(ABC) transporter
Trad_1013	COG1131	(ABC) transporter
Trad_1016	COG0003	Pfam Anion-transporting ATPase
Trad_1018	COG1966	Carbon starvation protein
Trad_1021	COG2010	Cytochrome c
Trad_1026	COG0437	4 iron, 4 sulfur cluster binding
Trad_1028	COG0009	L-threonylcarbamoyladenylate synthase
Trad_1030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Trad_1033	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Trad_1034	COG0049	tRNA binding
Trad_1035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Trad_1036	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Trad_1037	COG0051	transcription antitermination factor activity, RNA binding
Trad_1038	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Trad_1039	COG0088	Forms part of the polypeptide exit tunnel
Trad_1040	COG0089	rRNA binding
Trad_1041	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Trad_1042	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Trad_1043	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Trad_1044	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Trad_1045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Trad_1046	COG0255	Belongs to the universal ribosomal protein uL29 family
Trad_1047	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Trad_1048	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Trad_1051	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Trad_1053	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Trad_1054	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Trad_1055	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Trad_1056	COG1841	ribosomal large subunit assembly
Trad_1057	COG0200	Binds to the 23S rRNA
Trad_1058	COG0201	protein transport
Trad_1059	COG0563	adenylate kinase activity
Trad_1060	COG0024	Methionine aminopeptidase
Trad_1061	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Trad_1063	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Trad_1064	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Trad_1065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Trad_1066	COG0202	RNA polymerase activity
Trad_1067	COG0203	ribosomal protein L17
Trad_1069	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Trad_1070	COG1136	(ABC) transporter
Trad_1071	COG1136	(ABC) transporter
Trad_1071	COG0577	efflux transmembrane transporter activity
Trad_1075	COG2197	response regulator
Trad_1076	COG0590	tRNA wobble adenosine to inosine editing
Trad_1076	COG0037	tRNA processing
Trad_1077	COG0316	Belongs to the HesB IscA family
Trad_1078	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Trad_1079	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Trad_1080	COG0509	glycine decarboxylation via glycine cleavage system
Trad_1081	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Trad_1082	COG1100	Small GTP-binding protein
Trad_1084	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Trad_1086	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Trad_1087	COG0825	malonyl-CoA metabolic process
Trad_1088	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Trad_1090	COG2897	thiosulfate sulfurtransferase activity
Trad_1092	COG1959	2 iron, 2 sulfur cluster binding
Trad_1093	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Trad_1097	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Trad_1098	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Trad_1103	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Trad_1103	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Trad_1104	COG0420	3'-5' exonuclease activity
Trad_1105	COG0419	ATPase involved in DNA repair
Trad_1108	COG0492	ferredoxin-NADP+ reductase activity
Trad_1112	COG0142	geranyltranstransferase activity
Trad_1114	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Trad_1115	COG0511	ligase activity, forming carbon-carbon bonds
Trad_1116	COG0439	Biotin carboxylase
Trad_1117	COG1302	Protein conserved in bacteria
Trad_1118	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Trad_1119	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Trad_1122	COG2309	aminopeptidase activity
Trad_1123	COG2050	protein possibly involved in aromatic compounds catabolism
Trad_1125	COG0667	Aldo Keto reductase
Trad_1132	COG1846	Transcriptional regulator
Trad_1133	COG2259	Doxx family
Trad_1134	COG2514	catechol 2,3-dioxygenase activity
Trad_1135	COG0123	including yeast histone deacetylase and acetoin utilization protein
Trad_1141	COG1172	Belongs to the binding-protein-dependent transport system permease family
Trad_1142	COG1172	Belongs to the binding-protein-dependent transport system permease family
Trad_1143	COG1129	ABC transporter
Trad_1145	COG3396	Phenylacetate-CoA oxygenase
Trad_1148	COG2151	metal-sulfur cluster biosynthetic enzyme
Trad_1150	COG0628	permease
Trad_1151	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Trad_1152	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Trad_1153	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Trad_1156	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Trad_1157	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Trad_1158	COG4558	Periplasmic binding protein
Trad_1162	COG0778	Nitroreductase
Trad_1163	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Trad_1165	COG0154	amidase activity
Trad_1168	COG1136	(ABC) transporter
Trad_1182	COG1752	Esterase of the alpha-beta hydrolase superfamily
Trad_1184	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Trad_1190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Trad_1191	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Trad_1198	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Trad_1200	COG0395	ABC-type sugar transport system, permease component
Trad_1201	COG1175	transmembrane transport
Trad_1202	COG2182	Extracellular solute-binding protein
Trad_1204	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_1205	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Trad_1207	COG2226	methyltransferase
Trad_1209	COG0445	tRNA wobble uridine modification
Trad_1214	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Trad_1215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Trad_1216	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Trad_1217	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Trad_1220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Trad_1223	COG0371	Dehydrogenase
Trad_1226	COG1234	tRNA 3'-trailer cleavage
Trad_1227	COG1012	belongs to the aldehyde dehydrogenase family
Trad_1228	COG3718	enzyme involved in inositol metabolism
Trad_1229	COG1082	Xylose isomerase domain protein TIM barrel
Trad_1231	COG0673	inositol 2-dehydrogenase activity
Trad_1232	COG3962	Belongs to the TPP enzyme family
Trad_1233	COG0673	inositol 2-dehydrogenase activity
Trad_1235	COG4214	carbohydrate transport
Trad_1237	COG1349	DNA-binding transcription factor activity
Trad_1242	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Trad_1243	COG0446	pyridine nucleotide-disulphide oxidoreductase
Trad_1248	COG4214	carbohydrate transport
Trad_1249	COG4213	ABC transporter substrate-binding protein
Trad_1258	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Trad_1259	COG0045	succinate-CoA ligase (ADP-forming) activity
Trad_1260	COG3119	arylsulfatase activity
Trad_1262	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Trad_1263	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Trad_1265	COG0505	Belongs to the CarA family
Trad_1266	COG0628	permease
Trad_1269	COG0628	permease
Trad_1270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Trad_1273	COG1490	D-aminoacyl-tRNA deacylase activity
Trad_1275	COG1573	uracil-dna glycosylase
Trad_1282	COG0552	protein localization to endoplasmic reticulum
Trad_1283	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Trad_1285	COG1968	undecaprenyl-diphosphatase activity
Trad_1286	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Trad_1287	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Trad_1290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_1291	COG1136	(ABC) transporter
Trad_1292	COG0747	negative chemotaxis
Trad_1293	COG0601	transmembrane transport
Trad_1295	COG0277	FAD linked oxidase domain protein
Trad_1296	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Trad_1299	COG0488	(ABC) transporter
Trad_1308	COG0481	GTPase activity
Trad_1313	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Trad_1315	COG1396	sequence-specific DNA binding
Trad_1317	COG0601	transmembrane transport
Trad_1318	COG0747	negative chemotaxis
Trad_1319	COG0006	proline dipeptidase activity
Trad_1322	COG0667	Aldo Keto reductase
Trad_1323	COG1131	(ABC) transporter
Trad_1326	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Trad_1327	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Trad_1328	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Trad_1329	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Trad_1330	COG1450	Type ii and iii secretion system protein
Trad_1336	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Trad_1337	COG0305	Participates in initiation and elongation during chromosome replication
Trad_1338	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Trad_1339	COG2264	protein methyltransferase activity
Trad_1343	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Trad_1343	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Trad_1345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Trad_1347	COG0195	Participates in both transcription termination and antitermination
Trad_1348	COG0779	Required for maturation of 30S ribosomal subunits
Trad_1349	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Trad_1352	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Trad_1353	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Trad_1353	COG0072	phenylalanine-tRNA ligase activity
Trad_1354	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Trad_1355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Trad_1359	COG0793	Belongs to the peptidase S41A family
Trad_1360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Trad_1364	COG1940	carbohydrate kinase activity
Trad_1369	COG1024	Enoyl-CoA hydratase
Trad_1371	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Trad_1373	COG0187	DNA topoisomerase II activity
Trad_1374	COG1515	deoxyribonuclease V activity
Trad_1376	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Trad_1377	COG0217	transcriptional regulatory protein
Trad_1380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Trad_1381	COG0516	GMP reductase activity
Trad_1381	COG0517	IMP dehydrogenase activity
Trad_1383	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Trad_1389	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Trad_1390	COG0066	3-isopropylmalate dehydratase activity
Trad_1392	COG0189	ligase activity
Trad_1395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Trad_1396	COG0402	S-adenosylhomocysteine deaminase activity
Trad_1399	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Trad_1400	COG0494	nUDIX hydrolase
Trad_1401	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Trad_1402	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
Trad_1404	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_1405	COG1597	lipid kinase activity
Trad_1406	COG1024	Enoyl-CoA hydratase
Trad_1406	COG1250	3-hydroxyacyl-CoA dehydrogenase
Trad_1407	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_1408	COG0484	heat shock protein binding
Trad_1409	COG0789	Transcriptional regulator
Trad_1410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_1414	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Trad_1416	COG3842	ATPase activity
Trad_1421	COG0366	Alpha amylase catalytic
Trad_1435	COG1187	pseudouridine synthase activity
Trad_1436	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Trad_1437	COG0739	heme binding
Trad_1441	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Trad_1441	COG5297	Belongs to the glycosyl hydrolase family 6
Trad_1442	COG0366	Alpha amylase catalytic
Trad_1444	COG1175	transmembrane transport
Trad_1445	COG0395	ABC-type sugar transport system, permease component
Trad_1453	COG0180	Tryptophanyl-tRNA synthetase
Trad_1456	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Trad_1458	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Trad_1459	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Trad_1462	COG0285	dihydrofolate synthase activity
Trad_1463	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Trad_1465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Trad_1468	COG3206	protein involved in exopolysaccharide biosynthesis
Trad_1470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Trad_1471	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Trad_1474	COG1940	carbohydrate kinase activity
Trad_1478	COG0154	amidase activity
Trad_1483	COG0647	UMP catabolic process
Trad_1486	COG4214	carbohydrate transport
Trad_1487	COG1609	Transcriptional regulator
Trad_1489	COG2160	L-arabinose isomerase activity
Trad_1491	COG4585	Histidine kinase
Trad_1492	COG2197	response regulator
Trad_1495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Trad_1496	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Trad_1498	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Trad_1499	COG1620	l-lactate permease
Trad_1500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Trad_1503	COG3195	allantoin biosynthetic process
Trad_1503	COG3648	Uricase
Trad_1504	COG2351	hydroxyisourate hydrolase activity
Trad_1505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Trad_1506	COG3257	ureidoglycine aminohydrolase activity
Trad_1511	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Trad_1513	COG2226	methyltransferase
Trad_1515	COG2815	serine threonine protein kinase
Trad_1515	COG0515	serine threonine protein kinase
Trad_1526	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Trad_1527	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Trad_1530	COG1175	transmembrane transport
Trad_1531	COG0395	ABC-type sugar transport system, permease component
Trad_1533	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Trad_1538	COG1012	belongs to the aldehyde dehydrogenase family
Trad_1540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Trad_1541	COG2224	Isocitrate lyase
Trad_1544	COG2197	response regulator
Trad_1546	COG1196	nuclear chromosome segregation
Trad_1553	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Trad_1554	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Trad_1555	COG0047	phosphoribosylformylglycinamidine synthase activity
Trad_1556	COG0156	8-amino-7-oxononanoate synthase activity
Trad_1559	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Trad_1560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Trad_1563	COG2197	response regulator
Trad_1566	COG0577	efflux transmembrane transporter activity
Trad_1566	COG1136	(ABC) transporter
Trad_1567	COG2409	Drug exporters of the RND superfamily
Trad_1568	COG0277	FAD linked oxidase domain protein
Trad_1569	COG0277	FAD linked oxidase domain protein
Trad_1570	COG0247	lactate metabolic process
Trad_1571	COG1174	glycine betaine transport
Trad_1572	COG0517	IMP dehydrogenase activity
Trad_1572	COG1125	glycine betaine transport
Trad_1573	COG1174	glycine betaine transport
Trad_1574	COG1732	Glycine betaine
Trad_1576	COG1181	Belongs to the D-alanine--D-alanine ligase family
Trad_1579	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Trad_1580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Trad_1583	COG0640	Transcriptional regulator
Trad_1586	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Trad_1587	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Trad_1588	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Trad_1589	COG3850	Histidine kinase
Trad_1589	COG5002	protein histidine kinase activity
Trad_1591	COG1854	S-ribosylhomocysteine lyase activity
Trad_1596	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Trad_1597	COG1744	ABC transporter substrate-binding protein PnrA-like
Trad_1598	COG2001	Belongs to the MraZ family
Trad_1599	COG0275	rRNA processing
Trad_1602	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Trad_1603	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Trad_1604	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Trad_1605	COG0772	Belongs to the SEDS family
Trad_1606	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Trad_1607	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Trad_1608	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Trad_1609	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Trad_1611	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Trad_1612	COG0494	nUDIX hydrolase
Trad_1613	COG0196	riboflavin kinase activity
Trad_1614	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Trad_1615	COG4946	Tricorn protease homolog
Trad_1615	COG0823	Involved in the tonB-independent uptake of proteins
Trad_1615	COG1506	peptidase
Trad_1618	COG0432	Pfam Uncharacterised protein family UPF0047
Trad_1619	COG1072	(Pantothenic acid kinase))
Trad_1621	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Trad_1622	COG1185	polyribonucleotide nucleotidyltransferase activity
Trad_1623	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Trad_1625	COG0667	Aldo Keto reductase
Trad_1626	COG0667	Aldo Keto reductase
Trad_1627	COG0656	L-ascorbic acid biosynthetic process
Trad_1630	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Trad_1633	COG0473	3-isopropylmalate dehydrogenase activity
Trad_1635	COG0534	Mate efflux family protein
Trad_1636	COG2321	neutral zinc metallopeptidase
Trad_1637	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Trad_1638	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Trad_1647	COG0215	cysteine-tRNA ligase activity
Trad_1648	COG0758	DNA mediated transformation
Trad_1649	COG0366	Alpha amylase catalytic
Trad_1650	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Trad_1653	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Trad_1672	COG1518	maintenance of DNA repeat elements
Trad_1673	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Trad_1675	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_1680	COG1320	monovalent cation:proton antiporter activity
Trad_1682	COG2111	Na H antiporter
Trad_1682	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Trad_1683	COG1006	Multisubunit Na H antiporter MnhC subunit
Trad_1684	COG1007	ATP synthesis coupled electron transport
Trad_1689	COG0813	purine-nucleoside phosphorylase activity
Trad_1690	COG1250	3-hydroxyacyl-CoA dehydrogenase
Trad_1691	COG1024	Enoyl-CoA hydratase
Trad_1694	COG2267	carboxylic ester hydrolase activity
Trad_1699	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Trad_1700	COG1160	GTP binding
Trad_1701	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Trad_1702	COG0242	peptide deformylase activity
Trad_1704	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Trad_1709	COG0354	folic acid binding
Trad_1711	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Trad_1713	COG1070	Carbohydrate kinase
Trad_1714	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Trad_1716	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Trad_1718	COG0747	negative chemotaxis
Trad_1720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_1721	COG0402	S-adenosylhomocysteine deaminase activity
Trad_1723	COG1960	acyl-CoA dehydrogenase activity
Trad_1729	COG1653	transport
Trad_1731	COG0395	ABC-type sugar transport system, permease component
Trad_1732	COG0179	Fumarylacetoacetate (FAA) hydrolase
Trad_1734	COG1175	transmembrane transport
Trad_1735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Trad_1737	COG4175	Glycine betaine
Trad_1737	COG3448	diguanylate cyclase activity
Trad_1738	COG4176	ABC-type proline glycine betaine transport system permease component
Trad_1745	COG0651	ATP synthesis coupled electron transport
Trad_1749	COG1320	monovalent cation:proton antiporter activity
Trad_1752	COG0137	argininosuccinate synthase activity
Trad_1756	COG0165	Argininosuccinate lyase
Trad_1757	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Trad_1758	COG3706	GGDEF domain
Trad_1758	COG0745	RESPONSE REGULATOR receiver
Trad_1759	COG0252	asparaginase activity
Trad_1764	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Trad_1766	COG0343	queuine tRNA-ribosyltransferase activity
Trad_1767	COG1484	DNA-dependent DNA replication
Trad_1769	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Trad_1771	COG0124	histidyl-tRNA synthetase
Trad_1772	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Trad_1774	COG0017	Asparaginyl-tRNA synthetase
Trad_1779	COG0488	(ABC) transporter
Trad_1783	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_1793	COG0517	IMP dehydrogenase activity
Trad_1799	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Trad_1799	COG0574	Belongs to the PEP-utilizing enzyme family
Trad_1800	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_1801	COG1653	transport
Trad_1802	COG1104	cysteine desulfurase activity
Trad_1803	COG1959	2 iron, 2 sulfur cluster binding
Trad_1811	COG4974	Belongs to the 'phage' integrase family
Trad_1817	COG0470	DNA polymerase III
Trad_1827	COG1609	Transcriptional regulator
Trad_1828	COG0395	ABC-type sugar transport system, permease component
Trad_1829	COG1175	transmembrane transport
Trad_1831	COG2081	HI0933 family
Trad_1832	COG0667	Aldo Keto reductase
Trad_1836	COG0673	inositol 2-dehydrogenase activity
Trad_1838	COG0747	negative chemotaxis
Trad_1841	COG0673	inositol 2-dehydrogenase activity
Trad_1842	COG0673	inositol 2-dehydrogenase activity
Trad_1843	COG0673	inositol 2-dehydrogenase activity
Trad_1846	COG0673	inositol 2-dehydrogenase activity
Trad_1849	COG4608	Belongs to the ABC transporter superfamily
Trad_1851	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_1852	COG4174	ABC transporter (Permease)
Trad_1853	COG2813	Specifically methylates the guanine in position
Trad_1854	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Trad_1855	COG0438	transferase activity, transferring glycosyl groups
Trad_1866	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Trad_1867	COG1573	uracil-dna glycosylase
Trad_1868	COG1045	serine acetyltransferase
Trad_1870	COG2267	carboxylic ester hydrolase activity
Trad_1872	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_1873	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Trad_1878	COG2226	methyltransferase
Trad_1879	COG2261	transglycosylase associated protein
Trad_1880	COG0506	proline dehydrogenase activity
Trad_1881	COG1012	belongs to the aldehyde dehydrogenase family
Trad_1888	COG2368	4-hydroxyphenylacetate
Trad_1890	COG1012	belongs to the aldehyde dehydrogenase family
Trad_1893	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Trad_1894	COG2050	protein possibly involved in aromatic compounds catabolism
Trad_1895	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Trad_1898	COG1012	belongs to the aldehyde dehydrogenase family
Trad_1898	COG2030	dehydratase
Trad_1900	COG2010	Cytochrome c
Trad_1901	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Trad_1902	COG0581	inorganic phosphate transmembrane transporter activity
Trad_1903	COG0573	inorganic phosphate transmembrane transporter activity
Trad_1904	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Trad_1907	COG3639	organic phosphonate transmembrane transporter activity
Trad_1908	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Trad_1911	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Trad_1912	COG3639	organic phosphonate transmembrane transporter activity
Trad_1916	COG1733	regulation of RNA biosynthetic process
Trad_1920	COG0534	Mate efflux family protein
Trad_1922	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Trad_1924	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Trad_1925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Trad_1926	COG4591	ABC-type transport system involved in lipoprotein release permease component
Trad_1930	COG2050	protein possibly involved in aromatic compounds catabolism
Trad_1931	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Trad_1934	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Trad_1935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Trad_1936	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Trad_1937	COG0805	protein transport
Trad_1938	COG1605	Chorismate mutase
Trad_1938	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Trad_1944	COG0673	inositol 2-dehydrogenase activity
Trad_1945	COG1205	dead DEAH box helicase
Trad_1945	COG1111	helicase
Trad_1946	COG0463	Glycosyl transferase, family 2
Trad_1953	COG0628	permease
Trad_1954	COG0504	CTP synthase activity
Trad_1959	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_1960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Trad_1961	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Trad_1962	COG0667	Aldo Keto reductase
Trad_1963	COG0205	6-phosphofructokinase activity
Trad_1968	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Trad_1969	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Trad_1970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Trad_1972	COG0586	Pfam SNARE associated Golgi protein
Trad_1974	COG0322	excinuclease ABC activity
Trad_1977	COG0395	ABC-type sugar transport system, permease component
Trad_1979	COG1486	melibiose metabolic process
Trad_1981	COG0339	signal peptide processing
Trad_1982	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Trad_1982	COG2199	diguanylate cyclase activity
Trad_1984	COG0183	Belongs to the thiolase family
Trad_1985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Trad_1986	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Trad_1987	COG2313	pseudouridylate synthase activity
Trad_1991	COG1136	(ABC) transporter
Trad_1991	COG0577	efflux transmembrane transporter activity
Trad_1992	COG2363	Small membrane protein
Trad_1993	COG3685	Protein conserved in bacteria
Trad_1995	COG1305	Transglutaminase-like
Trad_1998	COG2308	Evidence 4 Homologs of previously reported genes of
Trad_1999	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Trad_2000	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2004	COG0514	ATP-dependent DNA helicase (RecQ)
Trad_2008	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Trad_2009	COG3132	Protein of unknown function, DUF480
Trad_2010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Trad_2012	COG1126	abc transporter atp-binding protein
Trad_2013	COG0765	amino acid transport
Trad_2014	COG4597	amino acid ABC transporter
Trad_2015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Trad_2016	COG1394	ATPase activity, coupled to movement of substances
Trad_2017	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Trad_2018	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Trad_2020	COG1527	subunit (C
Trad_2023	COG1269	ATP hydrolysis coupled proton transport
Trad_2025	COG0515	serine threonine protein kinase
Trad_2025	COG2815	serine threonine protein kinase
Trad_2029	COG0494	nUDIX hydrolase
Trad_2030	COG3956	TIGRFAM MazG family protein
Trad_2035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Trad_2036	COG1609	Transcriptional regulator
Trad_2037	COG1874	Beta-galactosidase
Trad_2040	COG1175	transmembrane transport
Trad_2041	COG0395	ABC-type sugar transport system, permease component
Trad_2051	COG0668	transmembrane transport
Trad_2052	COG0416	fatty acid biosynthetic process
Trad_2053	COG0564	pseudouridine synthase activity
Trad_2055	COG0438	transferase activity, transferring glycosyl groups
Trad_2061	COG1846	Transcriptional regulator
Trad_2065	COG2205	protein histidine kinase activity
Trad_2067	COG2045	Belongs to the ComB family
Trad_2069	COG0393	Putative heavy-metal-binding
Trad_2070	COG0017	Asparaginyl-tRNA synthetase
Trad_2071	COG1435	thymidine kinase activity
Trad_2073	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Trad_2074	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Trad_2078	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Trad_2085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Trad_2086	COG0321	lipoyl(octanoyl) transferase activity
Trad_2088	COG1278	Cold shock
Trad_2091	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Trad_2096	COG3507	Belongs to the glycosyl hydrolase 43 family
Trad_2097	COG3693	PFAM glycoside hydrolase, family 10
Trad_2100	COG0395	ABC-type sugar transport system, permease component
Trad_2101	COG1175	transmembrane transport
Trad_2103	COG3693	PFAM glycoside hydrolase, family 10
Trad_2105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Trad_2106	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Trad_2107	COG3191	aminopeptidase activity
Trad_2108	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Trad_2112	COG4154	Belongs to the RbsD FucU family
Trad_2115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Trad_2117	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2117	COG0604	alcohol dehydrogenase
Trad_2117	COG3321	synthase
Trad_2118	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Trad_2119	COG4762	Protein conserved in bacteria
Trad_2121	COG0495	leucyl-tRNA aminoacylation
Trad_2125	COG1278	Cold shock
Trad_2126	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Trad_2129	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Trad_2130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Trad_2135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Trad_2138	COG1902	pentaerythritol trinitrate reductase activity
Trad_2139	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Trad_2142	COG3254	rhamnose metabolic process
Trad_2148	COG1546	Belongs to the CinA family
Trad_2148	COG1058	Belongs to the CinA family
Trad_2149	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Trad_2150	COG1418	mRNA catabolic process
Trad_2150	COG2433	Pfam Transposase IS66
Trad_2151	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Trad_2152	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Trad_2153	COG0193	aminoacyl-tRNA hydrolase activity
Trad_2154	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Trad_2155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Trad_2156	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Trad_2161	COG0596	Alpha beta hydrolase
Trad_2165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Trad_2168	COG1304	FMN binding
Trad_2173	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Trad_2173	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Trad_2181	COG1063	alcohol dehydrogenase
Trad_2182	COG2182	Extracellular solute-binding protein
Trad_2183	COG1175	transmembrane transport
Trad_2184	COG0395	ABC-type sugar transport system, permease component
Trad_2185	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2186	COG1063	alcohol dehydrogenase
Trad_2188	COG0508	dehydrogenase complex catalyzes the overall conversion of
Trad_2192	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2194	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Trad_2195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Trad_2198	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Trad_2205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Trad_2206	COG0066	3-isopropylmalate dehydratase activity
Trad_2210	COG0521	Mo-molybdopterin cofactor biosynthetic process
Trad_2213	COG4948	Mandelate Racemase Muconate Lactonizing
Trad_2214	COG0751	glycine-tRNA ligase activity
Trad_2215	COG0752	glycyl-tRNA synthetase alpha subunit
Trad_2216	COG0542	response to heat
Trad_2217	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Trad_2218	COG4956	integral membrane protein (PIN domain superfamily)
Trad_2223	COG0166	Belongs to the GPI family
Trad_2224	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Trad_2225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Trad_2225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Trad_2230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Trad_2232	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Trad_2236	COG2311	Membrane
Trad_2238	COG2311	Membrane
Trad_2242	COG1215	transferase activity, transferring glycosyl groups
Trad_2246	COG0393	Putative heavy-metal-binding
Trad_2248	COG1562	ergosterol biosynthetic process
Trad_2249	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Trad_2250	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2251	COG0693	protein deglycase activity
Trad_2254	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Trad_2255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Trad_2256	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Trad_2256	COG1116	anion transmembrane transporter activity
Trad_2260	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Trad_2261	COG0489	protein tyrosine kinase activity
Trad_2263	COG0519	Catalyzes the synthesis of GMP from XMP
Trad_2263	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Trad_2266	COG1473	amidohydrolase
Trad_2267	COG1420	regulation of RNA biosynthetic process
Trad_2268	COG0314	molybdopterin synthase activity
Trad_2270	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2274	COG3387	PFAM Glycoside hydrolase 15-related
Trad_2275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Trad_2277	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Trad_2278	COG2873	o-acetylhomoserine
Trad_2279	COG2873	o-acetylhomoserine
Trad_2280	COG1175	transmembrane transport
Trad_2281	COG0395	ABC-type sugar transport system, permease component
Trad_2287	COG0747	negative chemotaxis
Trad_2288	COG0601	transmembrane transport
Trad_2289	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_2290	COG0444	Belongs to the ABC transporter superfamily
Trad_2293	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Trad_2294	COG1172	Belongs to the binding-protein-dependent transport system permease family
Trad_2295	COG1129	ABC transporter
Trad_2297	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Trad_2298	COG1653	transport
Trad_2299	COG0395	ABC-type sugar transport system, permease component
Trad_2300	COG4209	transmembrane transport
Trad_2304	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Trad_2308	COG1857	crispr-associated protein
Trad_2314	COG0739	heme binding
Trad_2315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Trad_2316	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Trad_2317	COG1295	ribonuclease BN
Trad_2319	COG0126	phosphoglycerate kinase activity
Trad_2322	COG1960	acyl-CoA dehydrogenase activity
Trad_2324	COG1960	acyl-CoA dehydrogenase activity
Trad_2329	COG0133	tryptophan synthase activity
Trad_2330	COG0159	tryptophan synthase activity
Trad_2331	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Trad_2333	COG0084	hydrolase, TatD family'
Trad_2338	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Trad_2342	COG1304	FMN binding
Trad_2343	COG4555	ABC transporter
Trad_2344	COG1668	transmembrane transport
Trad_2345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Trad_2349	COG1132	(ABC) transporter
Trad_2350	COG1132	(ABC) transporter
Trad_2351	COG3842	ATPase activity
Trad_2355	COG0484	heat shock protein binding
Trad_2357	COG0683	leucine binding
Trad_2359	COG0559	Belongs to the binding-protein-dependent transport system permease family
Trad_2360	COG1022	Amp-dependent synthetase and ligase
Trad_2365	COG3844	kynureninase activity
Trad_2366	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Trad_2367	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Trad_2368	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Trad_2368	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Trad_2369	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Trad_2369	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Trad_2370	COG0083	homoserine kinase activity
Trad_2373	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Trad_2375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Trad_2376	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Trad_2377	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Trad_2377	COG1754	DNA topoisomerase type I activity
Trad_2379	COG2884	Cell division ATP-binding protein ftsE
Trad_2380	COG1404	Belongs to the peptidase S8 family
Trad_2381	COG1470	cell adhesion involved in biofilm formation
Trad_2382	COG0848	biopolymer transport protein
Trad_2383	COG0811	peptide transport
Trad_2384	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Trad_2385	COG1692	metallophosphoesterase
Trad_2387	COG3706	GGDEF domain
Trad_2387	COG0745	RESPONSE REGULATOR receiver
Trad_2388	COG1522	sequence-specific DNA binding
Trad_2393	COG2094	Belongs to the DNA glycosylase MPG family
Trad_2395	COG0655	NAD(P)H dehydrogenase (quinone) activity
Trad_2397	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Trad_2399	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_2402	COG1597	lipid kinase activity
Trad_2405	COG0004	ammonium transporteR
Trad_2407	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Trad_2409	COG0243	molybdopterin cofactor binding
Trad_2413	COG0667	Aldo Keto reductase
Trad_2417	COG0601	transmembrane transport
Trad_2419	COG2059	Chromate
Trad_2421	COG0531	amino acid
Trad_2422	COG1047	Peptidyl-prolyl cis-trans
Trad_2428	COG0644	oxidoreductase
Trad_2430	COG2271	Major facilitator Superfamily
Trad_2433	COG0438	transferase activity, transferring glycosyl groups
Trad_2436	COG0765	amino acid transport
Trad_2439	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Trad_2442	COG1175	transmembrane transport
Trad_2443	COG0395	ABC-type sugar transport system, permease component
Trad_2449	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Trad_2450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Trad_2452	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Trad_2455	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Trad_2455	COG2199	diguanylate cyclase activity
Trad_2463	COG2326	polyphosphate kinase activity
Trad_2467	COG1177	transmembrane transport
Trad_2468	COG1176	ABC-type spermidine putrescine transport system, permease component I
Trad_2475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Trad_2476	COG0085	RNA polymerase activity
Trad_2477	COG0222	ribosome binding
Trad_2478	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Trad_2479	COG0081	regulation of translation
Trad_2480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Trad_2481	COG0250	Participates in transcription elongation, termination and antitermination
Trad_2482	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Trad_2483	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Trad_2484	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Trad_2485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Trad_2485	COG1796	DNA polymerase
Trad_2487	COG0717	Belongs to the dCTP deaminase family
Trad_2488	COG2205	protein histidine kinase activity
Trad_2489	COG0745	RESPONSE REGULATOR receiver
Trad_2493	COG1215	transferase activity, transferring glycosyl groups
Trad_2498	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Trad_2499	COG0686	Belongs to the AlaDH PNT family
Trad_2501	COG0632	four-way junction helicase activity
Trad_2502	COG1193	negative regulation of DNA recombination
Trad_2507	COG1611	Belongs to the LOG family
Trad_2509	COG4585	Histidine kinase
Trad_2512	COG1404	Belongs to the peptidase S8 family
Trad_2516	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Trad_2528	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Trad_2531	COG0667	Aldo Keto reductase
Trad_2540	COG1132	(ABC) transporter
Trad_2541	COG1764	response to oxidative stress
Trad_2543	COG0556	nucleotide-excision repair
Trad_2546	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Trad_2548	COG0793	Belongs to the peptidase S41A family
Trad_2548	COG3409	Peptidoglycan-binding domain 1 protein
Trad_2550	COG3263	regulation of cellular component size
Trad_2551	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Trad_2553	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Trad_2555	COG0012	GTP binding
Trad_2556	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_2557	COG1268	BioY protein
Trad_2560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Trad_2562	COG0237	dephospho-CoA kinase activity
Trad_2563	COG0617	tRNA 3'-terminal CCA addition
Trad_2564	COG0628	permease
Trad_2567	COG0436	Aminotransferase
Trad_2573	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Trad_2575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Trad_2582	COG0442	prolyl-tRNA aminoacylation
Trad_2584	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_2586	COG0747	negative chemotaxis
Trad_2591	COG0539	negative regulation of cytoplasmic translation
Trad_2592	COG1704	LemA family
Trad_2593	COG0482	sulfurtransferase activity
Trad_2595	COG1494	fructose-1,6-bisphosphatase
Trad_2596	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Trad_2596	COG0140	phosphoribosyl-ATP diphosphatase activity
Trad_2597	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Trad_2598	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Trad_2599	COG0151	Belongs to the GarS family
Trad_2602	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Trad_2603	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Trad_2604	COG0585	pseudouridine synthase activity
Trad_2606	COG5002	protein histidine kinase activity
Trad_2607	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Trad_2608	COG1774	PSP1 C-terminal conserved region
Trad_2611	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Trad_2614	COG3842	ATPase activity
Trad_2619	COG0395	ABC-type sugar transport system, permease component
Trad_2621	COG0316	Belongs to the HesB IscA family
Trad_2621	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Trad_2622	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Trad_2629	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Trad_2634	COG0702	epimerase
Trad_2635	COG0142	geranyltranstransferase activity
Trad_2646	COG4948	Mandelate Racemase Muconate Lactonizing
Trad_2649	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Trad_2651	COG0346	lactoylglutathione lyase activity
Trad_2652	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Trad_2658	COG1840	ABC-type Fe3 transport system, periplasmic component
Trad_2660	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Trad_2661	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Trad_2663	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_2665	COG0328	RNA-DNA hybrid ribonuclease activity
Trad_2668	COG2197	response regulator
Trad_2669	COG0641	radical SAM
Trad_2672	COG0475	glutathione-regulated potassium exporter activity
Trad_2672	COG0589	response to stress
Trad_2673	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Trad_2674	COG1320	monovalent cation:proton antiporter activity
Trad_2675	COG2212	antiporter activity
Trad_2678	COG1006	Multisubunit Na H antiporter MnhC subunit
Trad_2679	COG2111	Na H antiporter
Trad_2682	COG1160	GTP binding
Trad_2687	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Trad_2694	COG0747	negative chemotaxis
Trad_2695	COG0667	Aldo Keto reductase
Trad_2696	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Trad_2697	COG0525	valine-tRNA ligase activity
Trad_2698	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Trad_2699	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Trad_2700	COG0300	oxidoreductase activity
Trad_2702	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Trad_2703	COG0167	dihydroorotate dehydrogenase activity
Trad_2704	COG1321	iron dependent repressor
Trad_2705	COG0546	phosphoglycolate phosphatase activity
Trad_2705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Trad_2707	COG4221	oxidoreductase activity
Trad_2711	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Trad_2718	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Trad_2720	COG2211	Major facilitator Superfamily
Trad_2730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Trad_2732	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Trad_2735	COG0537	adenosine 5'-monophosphoramidase activity
Trad_2736	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Trad_2737	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Trad_2741	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Trad_2752	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Trad_2754	COG0204	Acyl-transferase
Trad_2755	COG0776	regulation of translation
Trad_2756	COG1760	l-serine dehydratase
Trad_2757	COG1760	l-serine dehydratase
Trad_2758	COG1252	NADH dehydrogenase
Trad_2759	COG0483	inositol monophosphate 1-phosphatase activity
Trad_2762	COG1959	2 iron, 2 sulfur cluster binding
Trad_2763	COG0604	alcohol dehydrogenase
Trad_2763	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2763	COG3321	synthase
Trad_2764	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Trad_2766	COG0287	Prephenate dehydrogenase
Trad_2768	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Trad_2769	COG1408	metallophosphoesterase
Trad_2771	COG0183	Belongs to the thiolase family
Trad_2773	COG2202	Pas domain
Trad_2773	COG1366	Belongs to the anti-sigma-factor antagonist family
Trad_2774	COG4572	Cation transport regulator
Trad_2775	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2777	COG1845	cytochrome c oxidase, subunit III
Trad_2777	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Trad_2778	COG2010	Cytochrome c
Trad_2778	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Trad_2779	COG0109	protoheme IX farnesyltransferase activity
Trad_2779	COG1612	heme a metabolic process
Trad_2780	COG0109	protoheme IX farnesyltransferase activity
Trad_2780	COG1612	heme a metabolic process
Trad_2784	COG0052	Belongs to the universal ribosomal protein uS2 family
Trad_2785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Trad_2786	COG0528	UMP kinase activity
Trad_2787	COG0233	cytoplasmic translational termination
Trad_2788	COG0575	Belongs to the CDS family
Trad_2790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Trad_2791	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Trad_2792	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Trad_2794	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Trad_2795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Trad_2797	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Trad_2799	COG1307	EDD domain protein, DegV family
Trad_2802	COG2010	Cytochrome c
Trad_2802	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Trad_2803	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Trad_2804	COG1845	cytochrome c oxidase, subunit III
Trad_2805	COG2010	Cytochrome c
Trad_2812	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Trad_2814	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Trad_2816	COG0512	Glutamine amidotransferase of anthranilate synthase
Trad_2818	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Trad_2824	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Trad_2826	COG1428	Deoxynucleoside kinase
Trad_2827	COG1428	Deoxynucleoside kinase
Trad_2828	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Trad_2840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Trad_2841	COG0473	3-isopropylmalate dehydrogenase activity
Trad_2844	COG2177	Part of the ABC transporter FtsEX involved in
Trad_2848	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Trad_2850	COG0402	S-adenosylhomocysteine deaminase activity
Trad_2851	COG0860	N-Acetylmuramoyl-L-alanine amidase
Trad_2852	COG0494	nUDIX hydrolase
Trad_2856	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Trad_2862	COG0438	transferase activity, transferring glycosyl groups
Trad_2867	COG1091	dTDP-4-dehydrorhamnose reductase activity
Trad_2868	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Trad_2870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Trad_2874	COG1674	ftsk spoiiie
Trad_2875	COG0628	permease
Trad_2877	COG3833	ABC-type maltose transport systems, permease component
Trad_2878	COG1175	transmembrane transport
Trad_2880	COG1609	Transcriptional regulator
Trad_2884	COG0123	including yeast histone deacetylase and acetoin utilization protein
Trad_2887	COG1063	alcohol dehydrogenase
Trad_2888	COG1063	alcohol dehydrogenase
Trad_2889	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2890	COG1609	Transcriptional regulator
Trad_2893	COG0395	ABC-type sugar transport system, permease component
Trad_2894	COG1063	alcohol dehydrogenase
Trad_2895	COG1063	alcohol dehydrogenase
Trad_2896	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Trad_2905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Trad_2910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Trad_2911	COG0601	transmembrane transport
Trad_2917	COG2084	Dehydrogenase
Trad_2918	COG0071	Belongs to the small heat shock protein (HSP20) family
Trad_2920	COG4106	trans-aconitate 2-methyltransferase activity
Trad_2928	COG0459	protein refolding
Trad_2929	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Trad_2932	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Trad_2932	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Trad_2933	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Trad_2934	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Trad_2935	COG2205	protein histidine kinase activity
Trad_2936	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Trad_2937	COG0497	DNA recombination
Trad_2938	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Trad_2940	COG0656	L-ascorbic acid biosynthetic process
Trad_2949	COG1022	Amp-dependent synthetase and ligase
Trad_2950	COG1960	acyl-CoA dehydrogenase activity
Trad_2952	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Trad_2960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Trad_2962	COG0728	peptidoglycan biosynthetic process
Trad_2963	COG3347	Dehydrogenase
Trad_2963	COG1028	Short-chain dehydrogenase reductase Sdr
Trad_2964	COG1556	Lactate utilization protein
Trad_2965	COG1139	Iron-sulfur cluster binding protein
Trad_2966	COG0247	lactate metabolic process
Trad_2969	COG3118	belongs to the thioredoxin family
Trad_2970	COG0534	Mate efflux family protein
Trad_2972	COG0105	UTP biosynthetic process
Trad_2974	COG1007	ATP synthesis coupled electron transport
Trad_2975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Trad_2976	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Trad_2977	COG0713	ATP synthesis coupled electron transport
Trad_2978	COG0839	Belongs to the complex I subunit 6 family
Trad_2979	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Trad_2980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Trad_2981	COG1034	ATP synthesis coupled electron transport
Trad_2982	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Trad_2983	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Trad_2985	COG0649	NAD binding
Trad_2986	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Trad_2987	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Trad_2988	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Trad_2989	COG0735	belongs to the Fur family
Trad_2990	COG0039	L-malate dehydrogenase activity
Trad_2991	COG1475	DNA binding
Trad_2992	COG1192	Involved in chromosome partitioning
Trad_2993	COG0357	Ribosomal RNA small subunit methyltransferase G
Trad_2994	COG0445	tRNA wobble uridine modification
Trad_R0039	COG0415	Belongs to the DNA photolyase family