locus-tag	class	description
M5C92_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M5C92_00010	COG0592	DNA-directed DNA polymerase activity
M5C92_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M5C92_00025	COG0187	DNA topoisomerase II activity
M5C92_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M5C92_00075	COG0457	Tetratricopeptide repeat
M5C92_00075	COG0705	Rhomboid family
M5C92_00085	COG3764	Sortase (surface protein transpeptidase)
M5C92_00115	COG1716	ATPase activity
M5C92_00120	COG1716	ATPase activity
M5C92_00120	COG1131	(ABC) transporter
M5C92_00120	COG0842	Transport permease protein
M5C92_00150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M5C92_00155	COG1854	S-ribosylhomocysteine lyase activity
M5C92_00170	COG1780	Probably involved in ribonucleotide reductase function
M5C92_00175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M5C92_00180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M5C92_00190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M5C92_00195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M5C92_00210	COG0395	ABC-type sugar transport system, permease component
M5C92_00215	COG1175	transmembrane transport
M5C92_00235	COG2072	flavoprotein involved in K transport
M5C92_00245	COG1643	Atp-dependent helicase
M5C92_00250	COG2197	response regulator
M5C92_00255	COG4585	Histidine kinase
M5C92_00265	COG1131	(ABC) transporter
M5C92_00275	COG1136	(ABC) transporter
M5C92_00285	COG2197	response regulator
M5C92_00295	COG1328	CTP reductase activity
M5C92_00315	COG1136	(ABC) transporter
M5C92_00315	COG0577	efflux transmembrane transporter activity
M5C92_00320	COG1414	Transcriptional regulator
M5C92_00325	COG0246	Mannitol dehydrogenase
M5C92_00330	COG1312	Catalyzes the dehydration of D-mannonate
M5C92_00335	COG0800	Aldolase
M5C92_00340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M5C92_00345	COG2226	methyltransferase
M5C92_00355	COG1120	ATPase activity
M5C92_00365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_00380	COG1132	(ABC) transporter
M5C92_00385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M5C92_00390	COG1609	Transcriptional regulator
M5C92_00405	COG1175	transmembrane transport
M5C92_00410	COG0395	ABC-type sugar transport system, permease component
M5C92_00435	COG1487	ribonuclease activity
M5C92_00450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M5C92_00480	COG1172	Belongs to the binding-protein-dependent transport system permease family
M5C92_00485	COG1879	ABC-type sugar transport system periplasmic component
M5C92_00490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
M5C92_00490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
M5C92_00495	COG1486	melibiose metabolic process
M5C92_00520	COG0561	phosphatase activity
M5C92_00525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
M5C92_00540	COG0077	Prephenate dehydratase
M5C92_00565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
M5C92_00585	COG4868	Belongs to the UPF0371 family
M5C92_00590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M5C92_00640	COG0521	Mo-molybdopterin cofactor biosynthetic process
M5C92_00650	COG0315	cyclic pyranopterin monophosphate synthase activity
M5C92_00660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M5C92_00685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M5C92_00720	COG2267	carboxylic ester hydrolase activity
M5C92_00770	COG3655	Transcriptional regulator
M5C92_00780	COG2890	protein-(glutamine-N5) methyltransferase activity
M5C92_00780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M5C92_00785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M5C92_00785	COG1754	DNA topoisomerase type I activity
M5C92_00790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M5C92_00795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M5C92_00890	COG2184	nucleotidyltransferase activity
M5C92_00915	COG1192	Involved in chromosome partitioning
M5C92_00925	COG4974	Belongs to the 'phage' integrase family
M5C92_00975	COG0717	Belongs to the dCTP deaminase family
M5C92_00980	COG2111	Na H antiporter
M5C92_00980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M5C92_00985	COG1006	Multisubunit Na H antiporter MnhC subunit
M5C92_00990	COG0651	ATP synthesis coupled electron transport
M5C92_01020	COG4149	molybdate abc transporter
M5C92_01025	COG3842	ATPase activity
M5C92_01040	COG0662	Cupin 2, conserved barrel domain protein
M5C92_01080	COG1940	carbohydrate kinase activity
M5C92_01085	COG0390	transport system, permease component
M5C92_01095	COG1505	serine-type exopeptidase activity
M5C92_01105	COG0437	4 iron, 4 sulfur cluster binding
M5C92_01110	COG0243	molybdopterin cofactor binding
M5C92_01115	COG1937	Protein conserved in bacteria
M5C92_01120	COG0446	pyridine nucleotide-disulphide oxidoreductase
M5C92_01130	COG0437	4 iron, 4 sulfur cluster binding
M5C92_01135	COG0243	molybdopterin cofactor binding
M5C92_01145	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
M5C92_01150	COG0540	Belongs to the ATCase OTCase family
M5C92_01155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M5C92_01160	COG0284	orotidine-5'-phosphate decarboxylase activity
M5C92_01165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M5C92_01170	COG0167	dihydroorotate dehydrogenase activity
M5C92_01175	COG0443	Heat shock 70 kDa protein
M5C92_01180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M5C92_01185	COG0484	heat shock protein binding
M5C92_01210	COG0584	glycerophosphoryl diester phosphodiesterase
M5C92_01220	COG0823	Involved in the tonB-independent uptake of proteins
M5C92_01220	COG1506	peptidase
M5C92_01230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M5C92_01260	COG1028	Short-chain dehydrogenase reductase Sdr
M5C92_01275	COG0494	nUDIX hydrolase
M5C92_01290	COG0191	fructose-bisphosphate aldolase activity
M5C92_01300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M5C92_01305	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
M5C92_01310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M5C92_01315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M5C92_01345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M5C92_01375	COG0039	L-malate dehydrogenase activity
M5C92_01380	COG0728	peptidoglycan biosynthetic process
M5C92_01405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M5C92_01430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M5C92_01435	COG0406	alpha-ribazole phosphatase activity
M5C92_01435	COG0494	nUDIX hydrolase
M5C92_01455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M5C92_01460	COG0306	phosphate transporter
M5C92_01470	COG1115	amino acid carrier protein
M5C92_01480	COG0737	Belongs to the 5'-nucleotidase family
M5C92_01490	COG3485	protocatechuate 3,4-dioxygenase
M5C92_01495	COG0354	folic acid binding
M5C92_01505	COG1490	D-aminoacyl-tRNA deacylase activity
M5C92_01525	COG0738	Major facilitator superfamily
M5C92_01530	COG2390	Transcriptional regulator
M5C92_01550	COG1349	DNA-binding transcription factor activity
M5C92_01570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M5C92_01575	COG2376	Dihydroxyacetone kinase
M5C92_01585	COG0698	ribose 5-phosphate isomerase
M5C92_01590	COG0730	response to heat
M5C92_01595	COG0641	radical SAM
M5C92_01600	COG2814	Major facilitator Superfamily
M5C92_01605	COG1609	Transcriptional regulator
M5C92_01610	COG3119	arylsulfatase activity
M5C92_01620	COG0395	ABC-type sugar transport system, permease component
M5C92_01635	COG1501	Belongs to the glycosyl hydrolase 31 family
M5C92_01645	COG1349	DNA-binding transcription factor activity
M5C92_01655	COG1175	transmembrane transport
M5C92_01660	COG0395	ABC-type sugar transport system, permease component
M5C92_01685	COG2115	Belongs to the xylose isomerase family
M5C92_01690	COG1070	Carbohydrate kinase
M5C92_01695	COG4213	ABC transporter substrate-binding protein
M5C92_01705	COG4214	carbohydrate transport
M5C92_01710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M5C92_01715	COG1757	Na H antiporter
M5C92_01725	COG3250	beta-galactosidase activity
M5C92_01735	COG0395	ABC-type sugar transport system, permease component
M5C92_01745	COG1609	Transcriptional regulator
M5C92_01755	COG0395	ABC-type sugar transport system, permease component
M5C92_01760	COG1175	transmembrane transport
M5C92_01775	COG3250	beta-galactosidase activity
M5C92_01785	COG1609	Transcriptional regulator
M5C92_01795	COG2610	gluconate transmembrane transporter activity
M5C92_01815	COG3525	Glycosyl hydrolase, family 20, catalytic domain
M5C92_01820	COG3250	beta-galactosidase activity
M5C92_01825	COG1869	D-ribose catabolic process
M5C92_01835	COG1879	ABC-type sugar transport system periplasmic component
M5C92_01840	COG1172	Belongs to the binding-protein-dependent transport system permease family
M5C92_01845	COG1129	ABC transporter
M5C92_01850	COG1609	Transcriptional regulator
M5C92_01855	COG2226	methyltransferase
M5C92_01860	COG1116	anion transmembrane transporter activity
M5C92_01860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M5C92_01880	COG0737	Belongs to the 5'-nucleotidase family
M5C92_01890	COG1609	Transcriptional regulator
M5C92_01895	COG2271	Major facilitator Superfamily
M5C92_01900	COG1285	pathogenesis
M5C92_01920	COG3177	Filamentation induced by cAMP protein fic
M5C92_01925	COG1715	Restriction endonuclease
M5C92_01930	COG5290	Psort location Cytoplasmic, score
M5C92_01950	COG0366	Alpha amylase catalytic
M5C92_01955	COG0395	ABC-type sugar transport system, permease component
M5C92_01960	COG1175	transmembrane transport
M5C92_01975	COG0574	Belongs to the PEP-utilizing enzyme family
M5C92_01975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M5C92_01980	COG0277	FAD linked oxidase domain protein
M5C92_01980	COG0247	lactate metabolic process
M5C92_01990	COG2267	carboxylic ester hydrolase activity
M5C92_01995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M5C92_02000	COG0791	NLP P60 protein
M5C92_02005	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M5C92_02020	COG0037	tRNA processing
M5C92_02030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M5C92_02035	COG0302	gtp cyclohydrolase
M5C92_02045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M5C92_02065	COG1609	Transcriptional regulator
M5C92_02085	COG3250	beta-galactosidase activity
M5C92_02095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M5C92_02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M5C92_02100	COG1461	Dihydroxyacetone kinase
M5C92_02105	COG2376	Dihydroxyacetone kinase
M5C92_02115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
M5C92_02120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
M5C92_02130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M5C92_02135	COG2409	Drug exporters of the RND superfamily
M5C92_02140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M5C92_02145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M5C92_02155	COG3386	PFAM SMP-30 Gluconolaconase
M5C92_02160	COG0247	lactate metabolic process
M5C92_02165	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
M5C92_02170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M5C92_02185	COG1194	a g-specific adenine glycosylase
M5C92_02195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M5C92_02200	COG0569	domain protein
M5C92_02205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M5C92_02220	COG1846	Transcriptional regulator
M5C92_02225	COG0406	alpha-ribazole phosphatase activity
M5C92_02250	COG0395	ABC-type sugar transport system, permease component
M5C92_02255	COG1175	transmembrane transport
M5C92_02265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M5C92_02270	COG4948	Mandelate Racemase Muconate Lactonizing
M5C92_02275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M5C92_02280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M5C92_02285	COG1169	isochorismate synthase
M5C92_02290	COG2226	methyltransferase
M5C92_02295	COG0644	oxidoreductase
M5C92_02305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M5C92_02310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M5C92_02315	COG0649	NAD binding
M5C92_02325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M5C92_02330	COG1034	ATP synthesis coupled electron transport
M5C92_02335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
M5C92_02340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M5C92_02345	COG0839	Belongs to the complex I subunit 6 family
M5C92_02350	COG0713	ATP synthesis coupled electron transport
M5C92_02365	COG1007	ATP synthesis coupled electron transport
M5C92_02370	COG0142	geranyltranstransferase activity
M5C92_02375	COG0653	protein targeting
M5C92_02415	COG0419	ATPase involved in DNA repair
M5C92_02420	COG0420	3'-5' exonuclease activity
M5C92_02425	COG0483	inositol monophosphate 1-phosphatase activity
M5C92_02430	COG1162	GTPase activity
M5C92_02435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M5C92_02460	COG0657	acetylesterase activity
M5C92_02475	COG0601	transmembrane transport
M5C92_02480	COG0444	Belongs to the ABC transporter superfamily
M5C92_02485	COG4608	Belongs to the ABC transporter superfamily
M5C92_02490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M5C92_02500	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
M5C92_02505	COG0363	glucosamine-6-phosphate deaminase activity
M5C92_02515	COG1595	DNA-templated transcription, initiation
M5C92_02530	COG0791	NLP P60 protein
M5C92_02530	COG1388	LysM domain
M5C92_02530	COG3103	Sh3 type 3 domain protein
M5C92_02540	COG0508	dehydrogenase complex catalyzes the overall conversion of
M5C92_02540	COG0567	Dehydrogenase, E1 component
M5C92_02545	COG1253	flavin adenine dinucleotide binding
M5C92_02555	COG0739	heme binding
M5C92_02560	COG0584	glycerophosphoryl diester phosphodiesterase
M5C92_02600	COG0018	arginyl-trna synthetase
M5C92_02610	COG0460	homoserine dehydrogenase
M5C92_02615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M5C92_02620	COG0083	homoserine kinase activity
M5C92_02635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M5C92_02660	COG0356	it plays a direct role in the translocation of protons across the membrane
M5C92_02665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M5C92_02670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M5C92_02675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M5C92_02680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
M5C92_02685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
M5C92_02690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
M5C92_02695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
M5C92_02705	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
M5C92_02750	COG1609	Transcriptional regulator
M5C92_02760	COG1175	transmembrane transport
M5C92_02765	COG3833	ABC-type maltose transport systems, permease component
M5C92_02775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
M5C92_02780	COG3281	Trehalose synthase
M5C92_02785	COG0366	Alpha amylase catalytic
M5C92_02790	COG0366	Alpha amylase catalytic
M5C92_02815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M5C92_02820	COG0058	SHG alpha-glucan phosphorylase activity
M5C92_02825	COG0180	Tryptophanyl-tRNA synthetase
M5C92_02855	COG3480	Lon protease (S16) C-terminal proteolytic domain
M5C92_02865	COG1615	UPF0182 protein
M5C92_02870	COG0366	Alpha amylase catalytic
M5C92_02870	COG1470	cell adhesion involved in biofilm formation
M5C92_02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M5C92_02895	COG1131	(ABC) transporter
M5C92_02905	COG0387	Pfam Sodium calcium exchanger
M5C92_02915	COG1053	succinate dehydrogenase
M5C92_02940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
M5C92_02975	COG4585	Histidine kinase
M5C92_02980	COG2135	peptidase activity
M5C92_02985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M5C92_03000	COG1397	ADP-ribosylglycohydrolase
M5C92_03010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M5C92_03015	COG3177	Filamentation induced by cAMP protein fic
M5C92_03025	COG1404	Belongs to the peptidase S8 family
M5C92_03035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M5C92_03040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M5C92_03045	COG0154	amidase activity
M5C92_03050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M5C92_03100	COG0129	dihydroxy-acid dehydratase activity
M5C92_03105	COG2985	domain, Protein
M5C92_03105	COG0569	domain protein
M5C92_03115	COG0440	acetolactate synthase activity
M5C92_03120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M5C92_03140	COG0473	3-isopropylmalate dehydrogenase activity
M5C92_03145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M5C92_03175	COG0438	transferase activity, transferring glycosyl groups
M5C92_03180	COG4750	Nucleotidyl transferase
M5C92_03185	COG3475	LICD family
M5C92_03190	COG1215	transferase activity, transferring glycosyl groups
M5C92_03215	COG2244	polysaccharide biosynthetic process
M5C92_03220	COG0463	Glycosyl transferase, family 2
M5C92_03250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M5C92_03280	COG1946	Acyl-CoA thioesterase
M5C92_03295	COG0519	Catalyzes the synthesis of GMP from XMP
M5C92_03305	COG2354	Protein conserved in bacteria
M5C92_03310	COG3590	peptidase
M5C92_03320	COG1045	serine acetyltransferase
M5C92_03330	COG1739	Uncharacterized protein family UPF0029
M5C92_03345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M5C92_03375	COG1609	Transcriptional regulator
M5C92_03380	COG3250	beta-galactosidase activity
M5C92_03400	COG0667	Aldo Keto reductase
M5C92_03405	COG0544	peptidyl-prolyl cis-trans isomerase activity
M5C92_03410	COG0740	serine-type endopeptidase activity
M5C92_03415	COG0740	serine-type endopeptidase activity
M5C92_03420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
M5C92_03425	COG1605	Chorismate mutase
M5C92_03425	COG0287	Prephenate dehydrogenase
M5C92_03445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M5C92_03460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M5C92_03465	COG0285	dihydrofolate synthase activity
M5C92_03470	COG0105	UTP biosynthetic process
M5C92_03515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M5C92_03520	COG0228	four-way junction DNA binding
M5C92_03525	COG1837	Belongs to the UPF0109 family
M5C92_03530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M5C92_03540	COG0335	large ribosomal subunit rRNA binding
M5C92_03545	COG0681	Belongs to the peptidase S26 family
M5C92_03550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M5C92_03575	COG4974	Belongs to the 'phage' integrase family
M5C92_03580	COG1388	LysM domain
M5C92_03580	COG4942	peptidase
M5C92_03585	COG2860	membrane
M5C92_03590	COG0052	Belongs to the universal ribosomal protein uS2 family
M5C92_03595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M5C92_03605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M5C92_03610	COG0644	oxidoreductase
M5C92_03635	COG0233	cytoplasmic translational termination
M5C92_03640	COG0575	Belongs to the CDS family
M5C92_03645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M5C92_03655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M5C92_03660	COG0750	zinc metalloprotease
M5C92_03665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
M5C92_03675	COG0442	prolyl-tRNA aminoacylation
M5C92_03685	COG0779	Required for maturation of 30S ribosomal subunits
M5C92_03700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
M5C92_03705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
M5C92_03710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M5C92_03715	COG3852	Histidine kinase
M5C92_03720	COG0745	RESPONSE REGULATOR receiver
M5C92_03725	COG2271	Major facilitator Superfamily
M5C92_03735	COG3842	ATPase activity
M5C92_03765	COG0842	Transport permease protein
M5C92_03765	COG1129	ABC transporter
M5C92_03780	COG1185	polyribonucleotide nucleotidyltransferase activity
M5C92_03790	COG0612	Peptidase, M16
M5C92_03795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
M5C92_03800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M5C92_03815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M5C92_03820	COG1674	ftsk spoiiie
M5C92_03835	COG1546	Belongs to the CinA family
M5C92_03835	COG1058	Belongs to the CinA family
M5C92_03840	COG1396	sequence-specific DNA binding
M5C92_03850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M5C92_03855	COG2137	regulation of response to DNA damage stimulus
M5C92_03860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M5C92_03865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
M5C92_03875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M5C92_03885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M5C92_03895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M5C92_03900	COG0318	PFAM AMP-dependent synthetase and ligase
M5C92_03905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M5C92_03925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M5C92_03935	COG2001	Belongs to the MraZ family
M5C92_03940	COG0275	rRNA processing
M5C92_03950	COG0768	penicillin binding
M5C92_03955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M5C92_03960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M5C92_03965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M5C92_03970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M5C92_03975	COG0772	Belongs to the SEDS family
M5C92_03980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M5C92_03985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M5C92_03995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M5C92_04005	COG1799	cell septum assembly
M5C92_04020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
M5C92_04035	COG0587	DNA-directed DNA polymerase activity
M5C92_04050	COG0735	belongs to the Fur family
M5C92_04055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M5C92_04060	COG1121	(ABC) transporter
M5C92_04070	COG0423	glycine-tRNA ligase activity
M5C92_04095	COG0358	DNA primase activity
M5C92_04105	COG0805	protein transport
M5C92_04110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M5C92_04145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_04150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M5C92_04190	COG1090	epimerase
M5C92_04210	COG0009	L-threonylcarbamoyladenylate synthase
M5C92_04230	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M5C92_04255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M5C92_04260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M5C92_04265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M5C92_04285	COG1940	carbohydrate kinase activity
M5C92_04300	COG0174	glutamine synthetase
M5C92_04305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M5C92_04315	COG0174	glutamine synthetase
M5C92_04335	COG0508	dehydrogenase complex catalyzes the overall conversion of
M5C92_04340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M5C92_04350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M5C92_04365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M5C92_04405	COG0205	6-phosphofructokinase activity
M5C92_04410	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
M5C92_04415	COG2815	serine threonine protein kinase
M5C92_04415	COG0515	serine threonine protein kinase
M5C92_04430	COG0142	geranyltranstransferase activity
M5C92_04445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M5C92_04450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M5C92_04450	COG1199	ATP-dependent helicase activity
M5C92_04460	COG0187	DNA topoisomerase II activity
M5C92_04475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M5C92_04515	COG0569	domain protein
M5C92_04530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M5C92_04540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
M5C92_04605	COG2197	response regulator
M5C92_04610	COG1760	l-serine dehydratase
M5C92_04615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M5C92_04620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M5C92_04630	COG0438	transferase activity, transferring glycosyl groups
M5C92_04640	COG1051	belongs to the nudix hydrolase family
M5C92_04645	COG0217	transcriptional regulatory protein
M5C92_04650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
M5C92_04655	COG0632	four-way junction helicase activity
M5C92_04660	COG2255	four-way junction helicase activity
M5C92_04670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M5C92_04675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M5C92_04680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M5C92_04685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M5C92_04695	COG1196	nuclear chromosome segregation
M5C92_04700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M5C92_04705	COG0124	histidyl-tRNA synthetase
M5C92_04710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M5C92_04715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M5C92_04735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
M5C92_04750	COG2409	Drug exporters of the RND superfamily
M5C92_04760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M5C92_04770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M5C92_04775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M5C92_04795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M5C92_04805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M5C92_04810	COG2217	Heavy metal translocating P-type atpase
M5C92_04815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
M5C92_04820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M5C92_04825	COG0505	Belongs to the CarA family
M5C92_04830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M5C92_04840	COG0194	GDP metabolic process
M5C92_04845	COG1758	RNA polymerase activity
M5C92_04855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
M5C92_04860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M5C92_04865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M5C92_04875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M5C92_04880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M5C92_04885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M5C92_04890	COG0140	phosphoribosyl-ATP diphosphatase activity
M5C92_04895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M5C92_04925	COG4581	dead DEAH box helicase
M5C92_04935	COG1216	Glycosyl transferase, family 2
M5C92_04975	COG0205	6-phosphofructokinase activity
M5C92_04980	COG1160	GTP binding
M5C92_04985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
M5C92_05000	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M5C92_05025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M5C92_05040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M5C92_05045	COG0149	triose-phosphate isomerase activity
M5C92_05050	COG0126	phosphoglycerate kinase activity
M5C92_05055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M5C92_05060	COG1481	regulation of sporulation
M5C92_05075	COG0322	excinuclease ABC activity
M5C92_05080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M5C92_05100	COG0556	nucleotide-excision repair
M5C92_05105	COG0237	dephospho-CoA kinase activity
M5C92_05110	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
M5C92_05115	COG1136	(ABC) transporter
M5C92_05150	COG0469	pyruvate kinase activity
M5C92_05155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M5C92_05160	COG0134	indole-3-glycerol-phosphate synthase activity
M5C92_05170	COG0107	imidazoleglycerol-phosphate synthase activity
M5C92_05185	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
M5C92_05195	COG4122	O-methyltransferase activity
M5C92_05200	COG1222	aaa ATPase
M5C92_05220	COG1968	undecaprenyl-diphosphatase activity
M5C92_05235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M5C92_05245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M5C92_05245	COG0519	Catalyzes the synthesis of GMP from XMP
M5C92_05270	COG0587	DNA-directed DNA polymerase activity
M5C92_05285	COG1881	PFAM PEBP family protein
M5C92_05320	COG1119	ATPase activity
M5C92_05325	COG0297	glycogen (starch) synthase activity
M5C92_05335	COG1136	(ABC) transporter
M5C92_05345	COG0560	Phosphoserine phosphatase
M5C92_05345	COG3830	Belongs to the UPF0237 family
M5C92_05355	COG0488	(ABC) transporter
M5C92_05360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M5C92_05365	COG2151	metal-sulfur cluster biosynthetic enzyme
M5C92_05380	COG0396	ATPase activity
M5C92_05410	COG0728	peptidoglycan biosynthetic process
M5C92_05430	COG0497	DNA recombination
M5C92_05435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M5C92_05450	COG0647	UMP catabolic process
M5C92_05480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M5C92_05485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M5C92_05490	COG1121	(ABC) transporter
M5C92_05495	COG0803	Belongs to the bacterial solute-binding protein 9 family
M5C92_05500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M5C92_05515	COG1476	TRANSCRIPTIONal
M5C92_05525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M5C92_05530	COG1438	arginine binding
M5C92_05545	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
M5C92_05550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M5C92_05565	COG1902	pentaerythritol trinitrate reductase activity
M5C92_05570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M5C92_05585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
M5C92_05590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M5C92_05600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
M5C92_05605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M5C92_05615	COG0131	Imidazoleglycerol-phosphate dehydratase
M5C92_05625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M5C92_05630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M5C92_05635	COG1381	Involved in DNA repair and RecF pathway recombination
M5C92_05640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M5C92_05675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
M5C92_05685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M5C92_05690	COG0484	heat shock protein binding
M5C92_05695	COG1420	regulation of RNA biosynthetic process
M5C92_05715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M5C92_05720	COG0481	GTPase activity
M5C92_05745	COG0268	Binds directly to 16S ribosomal RNA
M5C92_05755	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M5C92_05760	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M5C92_05780	COG0433	COG0433 Predicted ATPase
M5C92_05795	COG0495	leucyl-tRNA aminoacylation
M5C92_05820	COG0813	purine-nucleoside phosphorylase activity
M5C92_05830	COG1435	thymidine kinase activity
M5C92_05850	COG0803	Belongs to the bacterial solute-binding protein 9 family
M5C92_05860	COG1121	(ABC) transporter
M5C92_05865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M5C92_05885	COG0671	phosphoesterase, PA-phosphatase related
M5C92_05905	COG1113	amino acid transport
M5C92_05910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M5C92_05910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M5C92_05920	COG2011	ABC-type metal ion transport system permease component
M5C92_05925	COG1464	Belongs to the NlpA lipoprotein family
M5C92_05930	COG1113	amino acid transport
M5C92_05940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M5C92_05945	COG2186	Transcriptional regulator
M5C92_05950	COG0477	Major facilitator Superfamily
M5C92_05960	COG0826	peptidase U32
M5C92_05965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
M5C92_05975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M5C92_06015	COG0726	polysaccharide deacetylase
M5C92_06020	COG0133	tryptophan synthase activity
M5C92_06025	COG1609	Transcriptional regulator
M5C92_06035	COG0738	Major facilitator superfamily
M5C92_06040	COG0235	Class ii aldolase
M5C92_06075	COG0270	DNA (cytosine-5-)-methyltransferase activity
M5C92_06095	COG0406	alpha-ribazole phosphatase activity
M5C92_06100	COG0799	negative regulation of ribosome biogenesis
M5C92_06110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
M5C92_06115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M5C92_06125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M5C92_06135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
M5C92_06140	COG1530	ribonuclease E activity
M5C92_06145	COG1271	oxidase subunit
M5C92_06150	COG1294	oxidase, subunit
M5C92_06155	COG4988	ABC transporter
M5C92_06160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M5C92_06170	COG1132	(ABC) transporter
M5C92_06175	COG1132	(ABC) transporter
M5C92_06195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M5C92_06200	COG0571	ribonuclease III activity
M5C92_06215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
M5C92_06230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M5C92_06240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M5C92_06250	COG1181	Belongs to the D-alanine--D-alanine ligase family
M5C92_06255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M5C92_06275	COG0438	transferase activity, transferring glycosyl groups
M5C92_06290	COG4975	Glucose uptake
M5C92_06295	COG0339	signal peptide processing
M5C92_06350	COG0179	Fumarylacetoacetate (FAA) hydrolase
M5C92_06355	COG1022	Amp-dependent synthetase and ligase
M5C92_06380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M5C92_06385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
M5C92_06395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M5C92_06405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M5C92_06430	COG2985	domain, Protein
M5C92_06430	COG0569	domain protein
M5C92_06445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M5C92_06520	COG1846	Transcriptional regulator
M5C92_06525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M5C92_06565	COG2801	Transposase and inactivated derivatives
M5C92_06590	COG1122	ATPase activity
M5C92_06615	COG1619	proteins homologs of microcin C7 resistance protein MccF
M5C92_06635	COG2177	Part of the ABC transporter FtsEX involved in
M5C92_06640	COG2884	Cell division ATP-binding protein ftsE
M5C92_06645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
M5C92_06705	COG0513	Belongs to the DEAD box helicase family
M5C92_06710	COG2095	MarC family integral membrane protein
M5C92_06720	COG0006	proline dipeptidase activity
M5C92_06725	COG2239	Acts as a magnesium transporter
M5C92_06750	COG1611	Belongs to the LOG family
M5C92_06760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M5C92_06765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M5C92_06785	COG1079	Belongs to the binding-protein-dependent transport system permease family
M5C92_06790	COG4603	Belongs to the binding-protein-dependent transport system permease family
M5C92_06795	COG3845	ABC transporter
M5C92_06800	COG1744	ABC transporter substrate-binding protein PnrA-like
M5C92_06805	COG0662	Cupin 2, conserved barrel domain protein
M5C92_06805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
M5C92_06820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M5C92_06825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
M5C92_06835	COG1268	BioY protein
M5C92_06845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M5C92_06850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M5C92_06855	COG4770	biotin carboxylase activity
M5C92_06875	COG0644	oxidoreductase
M5C92_06880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M5C92_06895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M5C92_06900	COG2271	Major facilitator Superfamily
M5C92_06905	COG2030	dehydratase
M5C92_06945	COG0039	L-malate dehydrogenase activity
M5C92_06955	COG0166	Belongs to the GPI family
M5C92_06960	COG0205	6-phosphofructokinase activity
M5C92_06990	COG0045	succinate-CoA ligase (ADP-forming) activity
M5C92_06995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M5C92_06995	COG2755	lipolytic protein G-D-S-L family
M5C92_07010	COG0653	protein targeting
M5C92_07040	COG0542	response to heat
M5C92_07095	COG4974	Belongs to the 'phage' integrase family
M5C92_07120	COG0857	belongs to the CobB CobQ family
M5C92_07120	COG0280	phosphate acetyltransferase
M5C92_07125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M5C92_07140	COG1136	(ABC) transporter
M5C92_07150	COG0114	fumarate hydratase activity
M5C92_07155	COG0516	GMP reductase activity
M5C92_07180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M5C92_07185	COG0151	Belongs to the GarS family
M5C92_07190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M5C92_07195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
M5C92_07200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M5C92_07205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M5C92_07210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M5C92_07225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
M5C92_07235	COG0428	transporter
M5C92_07240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M5C92_07245	COG0733	neurotransmitter:sodium symporter activity
M5C92_07255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M5C92_07260	COG1053	succinate dehydrogenase
M5C92_07285	COG0802	atpase or kinase
M5C92_07290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M5C92_07300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M5C92_07305	COG1072	(Pantothenic acid kinase))
M5C92_07315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M5C92_07320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M5C92_07330	COG4720	Psort location CytoplasmicMembrane, score
M5C92_07335	COG1122	ATPase activity
M5C92_07355	COG0101	tRNA pseudouridine synthase activity
M5C92_07360	COG1940	carbohydrate kinase activity
M5C92_07370	COG0765	amino acid transport
M5C92_07380	COG0789	Transcriptional regulator
M5C92_07390	COG0203	ribosomal protein L17
M5C92_07395	COG0202	RNA polymerase activity
M5C92_07405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
M5C92_07410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M5C92_07415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M5C92_07425	COG0563	adenylate kinase activity
M5C92_07435	COG0200	Binds to the 23S rRNA
M5C92_07440	COG1841	ribosomal large subunit assembly
M5C92_07445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
M5C92_07455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
M5C92_07460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
M5C92_07465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M5C92_07470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M5C92_07475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
M5C92_07480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M5C92_07495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M5C92_07500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M5C92_07505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
M5C92_07510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M5C92_07515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M5C92_07520	COG0089	rRNA binding
M5C92_07525	COG0088	Forms part of the polypeptide exit tunnel
M5C92_07530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
M5C92_07535	COG0051	transcription antitermination factor activity, RNA binding
M5C92_07540	COG0546	phosphoglycolate phosphatase activity
M5C92_07550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M5C92_07555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
M5C92_07560	COG0049	tRNA binding
M5C92_07565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
M5C92_07570	COG0833	amino acid
M5C92_07575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M5C92_07580	COG0085	RNA polymerase activity
M5C92_07585	COG0222	ribosome binding
M5C92_07590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M5C92_07600	COG0081	regulation of translation
M5C92_07605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M5C92_07610	COG0250	Participates in transcription elongation, termination and antitermination
M5C92_07625	COG0436	Aminotransferase
M5C92_07635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M5C92_07650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M5C92_07660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M5C92_07680	COG1666	GTP binding
M5C92_07690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M5C92_07695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M5C92_07700	COG5401	PFAM Sporulation and spore germination
M5C92_07705	COG5000	phosphorelay sensor kinase activity
M5C92_07705	COG5002	protein histidine kinase activity
M5C92_07710	COG0745	RESPONSE REGULATOR receiver
M5C92_07730	COG0714	Associated with various cellular activities
M5C92_07775	COG0483	inositol monophosphate 1-phosphatase activity
M5C92_07790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M5C92_07815	COG0438	transferase activity, transferring glycosyl groups
M5C92_07815	COG1216	Glycosyl transferase, family 2
M5C92_07885	COG0673	inositol 2-dehydrogenase activity
M5C92_07910	COG1088	dTDP-glucose 4,6-dehydratase activity
M5C92_07925	COG1316	TRANSCRIPTIONal
M5C92_07930	COG1316	TRANSCRIPTIONal
M5C92_07940	COG0642	Histidine kinase
M5C92_07945	COG0745	RESPONSE REGULATOR receiver
M5C92_07960	COG0424	maF-like protein
M5C92_07995	COG1217	gtp-binding protein TYPA
M5C92_08005	COG1132	(ABC) transporter
M5C92_08035	COG0321	lipoyl(octanoyl) transferase activity
M5C92_08040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M5C92_08050	COG1362	aminopeptidase activity
M5C92_08065	COG2838	Isocitrate dehydrogenase
M5C92_08070	COG2391	methyltransferase activity
M5C92_08075	COG0425	Belongs to the sulfur carrier protein TusA family
M5C92_08080	COG0366	Alpha amylase catalytic
M5C92_08085	COG1501	Belongs to the glycosyl hydrolase 31 family
M5C92_08095	COG0395	ABC-type sugar transport system, permease component
M5C92_08100	COG1175	transmembrane transport
M5C92_08105	COG1846	Transcriptional regulator
M5C92_08105	COG1940	carbohydrate kinase activity
M5C92_08130	COG1178	ABC-type Fe3 transport system permease component
M5C92_08135	COG3842	ATPase activity
M5C92_08140	COG1840	ABC-type Fe3 transport system, periplasmic component
M5C92_08160	COG4608	Belongs to the ABC transporter superfamily
M5C92_08165	COG0444	Belongs to the ABC transporter superfamily
M5C92_08170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M5C92_08185	COG2116	formate transmembrane transporter activity
M5C92_08195	COG0242	peptide deformylase activity
M5C92_08200	COG1970	mechanosensitive ion channel activity
M5C92_08225	COG0456	acetyltransferase
M5C92_08225	COG1846	Transcriptional regulator
M5C92_08230	COG1780	Probably involved in ribonucleotide reductase function
M5C92_08240	COG0431	NADPH-dependent FMN reductase
M5C92_08245	COG3226	Transcriptional regulator
M5C92_08250	COG0477	Major facilitator Superfamily
M5C92_08260	COG1834	amidinotransferase
M5C92_08265	COG0549	Belongs to the carbamate kinase family
M5C92_08270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M5C92_08290	COG0395	ABC-type sugar transport system, permease component
M5C92_08305	COG0366	Alpha amylase catalytic
M5C92_08320	COG0477	Major facilitator Superfamily
M5C92_08375	COG0012	GTP binding
M5C92_08380	COG1322	Protein conserved in bacteria
M5C92_08385	COG1162	GTPase activity
M5C92_08400	COG4555	ABC transporter
M5C92_08415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
M5C92_08425	COG1722	exodeoxyribonuclease VII activity
M5C92_08430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M5C92_08435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M5C92_08445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M5C92_08450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M5C92_08455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M5C92_08470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M5C92_08475	COG1012	belongs to the aldehyde dehydrogenase family
M5C92_08490	COG1131	(ABC) transporter
M5C92_08495	COG1725	Transcriptional regulator
M5C92_08520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M5C92_08540	COG0148	phosphopyruvate hydratase activity
M5C92_08555	COG0193	aminoacyl-tRNA hydrolase activity
M5C92_08560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
M5C92_08570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M5C92_08580	COG1309	transcriptional regulator
M5C92_08595	COG4152	abc transporter atp-binding protein
M5C92_08600	COG1668	transmembrane transport
M5C92_08610	COG0488	(ABC) transporter
M5C92_08615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
M5C92_08620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M5C92_08630	COG0084	hydrolase, TatD family'
M5C92_08635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M5C92_08640	COG1335	isochorismatase
M5C92_08660	COG2873	o-acetylhomoserine
M5C92_08680	COG1131	(ABC) transporter
M5C92_08695	COG2813	Specifically methylates the guanine in position
M5C92_08725	COG1620	l-lactate permease
M5C92_08730	COG0247	lactate metabolic process
M5C92_08740	COG1556	Lactate utilization protein
M5C92_08760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M5C92_08765	COG2190	(PTS) system
M5C92_08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5C92_08770	COG1263	PTS System
M5C92_08785	COG1051	belongs to the nudix hydrolase family
M5C92_08795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M5C92_08805	COG3711	transcriptional antiterminator
M5C92_08815	COG1511	domain protein
M5C92_08825	COG2848	UPF0210 protein
M5C92_08830	COG3830	Belongs to the UPF0237 family
M5C92_08845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M5C92_08850	COG0254	rRNA binding
M5C92_08855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M5C92_08860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M5C92_08865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M5C92_08880	COG0477	Major facilitator Superfamily
M5C92_08885	COG0657	acetylesterase activity
M5C92_08890	COG2188	Transcriptional regulator
M5C92_08895	COG1120	ATPase activity
M5C92_08900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_08905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_08910	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M5C92_08925	COG0596	Alpha beta hydrolase
M5C92_08945	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M5C92_09005	COG0791	NLP P60 protein
M5C92_09005	COG1388	LysM domain
M5C92_09015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M5C92_09020	COG2252	PERMEase
M5C92_09035	COG1278	Cold shock
M5C92_09045	COG1842	Phage shock protein A
M5C92_09055	COG0745	RESPONSE REGULATOR receiver
M5C92_09060	COG2205	protein histidine kinase activity
M5C92_09070	COG0300	oxidoreductase activity
M5C92_09085	COG0459	protein refolding
M5C92_09100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
M5C92_09145	COG0673	inositol 2-dehydrogenase activity
M5C92_09155	COG1653	transport
M5C92_09160	COG1175	transmembrane transport
M5C92_09190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M5C92_09205	COG1966	Carbon starvation protein
M5C92_09230	COG2233	PERMEase
M5C92_09245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M5C92_09250	COG0215	cysteine-tRNA ligase activity
M5C92_09275	COG2376	Dihydroxyacetone kinase
M5C92_09290	COG3775	system Galactitol-specific IIC component
M5C92_09310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
M5C92_09315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M5C92_09330	COG5002	protein histidine kinase activity
M5C92_09345	COG0588	phosphoglycerate mutase activity
M5C92_09390	COG1120	ATPase activity
M5C92_09395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_09425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M5C92_09430	COG0667	Aldo Keto reductase
M5C92_09440	COG0710	3-dehydroquinate dehydratase activity
M5C92_09470	COG0714	Associated with various cellular activities
M5C92_09485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M5C92_09490	COG1950	PFAM Membrane protein of
M5C92_09495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M5C92_09500	COG0586	Pfam SNARE associated Golgi protein
M5C92_09535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M5C92_09540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_09545	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_09550	COG1120	ATPase activity
M5C92_09570	COG1063	alcohol dehydrogenase
M5C92_09575	COG1609	Transcriptional regulator
M5C92_09580	COG2271	Major facilitator Superfamily
M5C92_09585	COG0483	inositol monophosphate 1-phosphatase activity
M5C92_09590	COG1879	ABC-type sugar transport system periplasmic component
M5C92_09595	COG1172	Belongs to the binding-protein-dependent transport system permease family
M5C92_09605	COG0673	inositol 2-dehydrogenase activity
M5C92_09615	COG0673	inositol 2-dehydrogenase activity
M5C92_09620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M5C92_09640	COG3718	enzyme involved in inositol metabolism
M5C92_09645	COG3962	Belongs to the TPP enzyme family
M5C92_09655	COG4604	ABC transporter, ATP-binding protein
M5C92_09660	COG4605	iron ion homeostasis
M5C92_09665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5C92_09670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M5C92_09675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M5C92_09685	COG0673	inositol 2-dehydrogenase activity
M5C92_09695	COG1175	transmembrane transport
M5C92_09700	COG0395	ABC-type sugar transport system, permease component
M5C92_09705	COG1063	alcohol dehydrogenase
M5C92_09710	COG0156	8-amino-7-oxononanoate synthase activity
M5C92_09720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
M5C92_09720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M5C92_09725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M5C92_09730	COG1904	glucuronate isomerase
M5C92_09755	COG3142	Participates in the control of copper homeostasis
M5C92_09770	COG1940	carbohydrate kinase activity
M5C92_09780	COG0601	transmembrane transport
M5C92_09785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M5C92_09795	COG1940	carbohydrate kinase activity
M5C92_09800	COG1940	carbohydrate kinase activity
M5C92_09800	COG1846	Transcriptional regulator
M5C92_09810	COG1175	transmembrane transport
M5C92_09840	COG2801	Transposase and inactivated derivatives
M5C92_09880	COG2801	Transposase and inactivated derivatives
M5C92_09885	COG1132	(ABC) transporter
M5C92_09890	COG2375	cellular response to nickel ion
M5C92_09890	COG1132	(ABC) transporter
M5C92_09895	COG1129	ABC transporter
M5C92_09900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M5C92_09915	COG0471	metal ion transport
M5C92_09945	COG1129	ABC transporter
M5C92_09950	COG1172	Belongs to the binding-protein-dependent transport system permease family
M5C92_09960	COG1879	ABC-type sugar transport system periplasmic component
M5C92_09970	COG1070	Carbohydrate kinase
M5C92_09995	COG1252	NADH dehydrogenase
M5C92_10005	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
M5C92_10040	COG1518	maintenance of DNA repeat elements
M5C92_10095	COG1643	Atp-dependent helicase
M5C92_10110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M5C92_10140	COG1136	(ABC) transporter
M5C92_10140	COG0577	efflux transmembrane transporter activity
M5C92_10145	COG1136	(ABC) transporter
M5C92_10160	COG0745	RESPONSE REGULATOR receiver
M5C92_10165	COG2205	protein histidine kinase activity
M5C92_10170	COG0343	queuine tRNA-ribosyltransferase activity
M5C92_10180	COG1428	Deoxynucleoside kinase
M5C92_10225	COG0351	phosphomethylpyrimidine kinase
M5C92_10235	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M5C92_10245	COG2814	Major facilitator Superfamily
M5C92_10250	COG0305	Participates in initiation and elongation during chromosome replication
M5C92_10270	COG0359	binds to the 23S rRNA
M5C92_10275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M5C92_10285	COG0360	Binds together with S18 to 16S ribosomal RNA
M5C92_10290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M5C92_10295	COG0628	permease
M5C92_10305	COG0617	tRNA 3'-terminal CCA addition
M5C92_10325	COG0492	ferredoxin-NADP+ reductase activity
M5C92_10330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M5C92_10335	COG1181	Belongs to the D-alanine--D-alanine ligase family
M5C92_10345	COG1192	Involved in chromosome partitioning
M5C92_10350	COG0357	Ribosomal RNA small subunit methyltransferase G
M5C92_10360	COG0706	membrane insertase activity
M5C92_10365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
M5C92_10370	COG0594	ribonuclease P activity
M5C92_10375	COG0230	Belongs to the bacterial ribosomal protein bL34 family