locus-tag	class	description
Tpau_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Tpau_0003	COG0592	DNA-directed DNA polymerase activity
Tpau_0004	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Tpau_0005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Tpau_0007	COG0477	Major facilitator Superfamily
Tpau_0008	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Tpau_0009	COG0187	DNA topoisomerase II activity
Tpau_0010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Tpau_0015	COG1253	flavin adenine dinucleotide binding
Tpau_0016	COG1253	flavin adenine dinucleotide binding
Tpau_0027	COG0515	serine threonine protein kinase
Tpau_0027	COG2815	serine threonine protein kinase
Tpau_0028	COG0515	serine threonine protein kinase
Tpau_0029	COG0768	penicillin binding
Tpau_0032	COG1716	ATPase activity
Tpau_0033	COG1716	ATPase activity
Tpau_0036	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tpau_0037	COG2814	Major facilitator Superfamily
Tpau_0041	COG1063	alcohol dehydrogenase
Tpau_0045	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0048	COG1073	alpha beta
Tpau_0053	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Tpau_0055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Tpau_0060	COG0297	glycogen (starch) synthase activity
Tpau_0068	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Tpau_0071	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Tpau_0074	COG3336	cytochrome c oxidase
Tpau_0087	COG0778	Nitroreductase
Tpau_0093	COG0745	RESPONSE REGULATOR receiver
Tpau_0094	COG2205	protein histidine kinase activity
Tpau_0097	COG0745	RESPONSE REGULATOR receiver
Tpau_0098	COG5002	protein histidine kinase activity
Tpau_0100	COG3559	Exporter of polyketide antibiotics
Tpau_0101	COG1131	(ABC) transporter
Tpau_0105	COG1252	NADH dehydrogenase
Tpau_0107	COG0070	glutamate synthase
Tpau_0107	COG0069	glutamate synthase activity
Tpau_0107	COG0067	glutamate synthase
Tpau_0112	COG2501	S4 domain
Tpau_0115	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_0125	COG2119	membrane
Tpau_0136	COG1316	TRANSCRIPTIONal
Tpau_0138	COG2252	PERMEase
Tpau_0140	COG3226	Transcriptional regulator
Tpau_0158	COG0561	phosphatase activity
Tpau_0160	COG2385	sporulation resulting in formation of a cellular spore
Tpau_0162	COG1216	Glycosyl transferase, family 2
Tpau_0164	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Tpau_0165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Tpau_0167	COG5001	Diguanylate cyclase
Tpau_0173	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_0176	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tpau_0177	COG0277	FAD linked oxidase domain protein
Tpau_0178	COG1956	GAF domain-containing protein
Tpau_0183	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Tpau_0184	COG1349	DNA-binding transcription factor activity
Tpau_0185	COG1105	Belongs to the carbohydrate kinase PfkB family
Tpau_0186	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Tpau_0186	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Tpau_0186	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Tpau_0189	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Tpau_0191	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Tpau_0192	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Tpau_0195	COG0583	DNA-binding transcription factor activity
Tpau_0198	COG3191	aminopeptidase activity
Tpau_0200	COG1846	Transcriptional regulator
Tpau_0208	COG0583	DNA-binding transcription factor activity
Tpau_0211	COG1396	sequence-specific DNA binding
Tpau_0212	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Tpau_0213	COG1760	l-serine dehydratase
Tpau_0214	COG0494	nUDIX hydrolase
Tpau_0215	COG3214	Protein conserved in bacteria
Tpau_0216	COG2184	nucleotidyltransferase activity
Tpau_0217	COG0488	(ABC) transporter
Tpau_0224	COG3012	SEC-C Motif Domain Protein
Tpau_0229	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Tpau_0238	COG2161	toxin-antitoxin pair type II binding
Tpau_0239	COG2026	Addiction module toxin, RelE StbE family
Tpau_0246	COG0515	serine threonine protein kinase
Tpau_0253	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Tpau_0280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_0284	COG0028	Belongs to the TPP enzyme family
Tpau_0323	COG3328	transposase activity
Tpau_0333	COG1404	Belongs to the peptidase S8 family
Tpau_0340	COG1309	transcriptional regulator
Tpau_0341	COG0183	Belongs to the thiolase family
Tpau_0351	COG3706	GGDEF domain
Tpau_0354	COG2197	response regulator
Tpau_0355	COG2217	Heavy metal translocating P-type atpase
Tpau_0358	COG4290	ribonuclease
Tpau_0359	COG1309	transcriptional regulator
Tpau_0364	COG2409	Drug exporters of the RND superfamily
Tpau_0366	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Tpau_0372	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Tpau_0373	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Tpau_0382	COG0583	DNA-binding transcription factor activity
Tpau_0386	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_0387	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0389	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0396	COG0577	efflux transmembrane transporter activity
Tpau_0396	COG1136	(ABC) transporter
Tpau_0418	COG4981	capsule polysaccharide biosynthetic process
Tpau_0423	COG1472	Belongs to the glycosyl hydrolase 3 family
Tpau_0424	COG1309	transcriptional regulator
Tpau_0427	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0428	COG0183	Belongs to the thiolase family
Tpau_0429	COG1832	CoA-binding protein
Tpau_0434	COG1960	acyl-CoA dehydrogenase activity
Tpau_0438	COG0477	Major facilitator Superfamily
Tpau_0444	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_0446	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Tpau_0446	COG2066	Belongs to the glutaminase family
Tpau_0450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Tpau_0465	COG0247	lactate metabolic process
Tpau_0465	COG2181	nitrate reductase activity
Tpau_0470	COG0708	Exodeoxyribonuclease III
Tpau_0482	COG4106	trans-aconitate 2-methyltransferase activity
Tpau_0483	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Tpau_0486	COG0443	Heat shock 70 kDa protein
Tpau_0487	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tpau_0488	COG0484	heat shock protein binding
Tpau_0489	COG0789	Transcriptional regulator
Tpau_0494	COG0542	response to heat
Tpau_0495	COG2267	carboxylic ester hydrolase activity
Tpau_0498	COG0371	Dehydrogenase
Tpau_0500	COG2149	membrane
Tpau_0504	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tpau_0507	COG0488	(ABC) transporter
Tpau_0508	COG0586	Pfam SNARE associated Golgi protein
Tpau_0509	COG0586	Pfam SNARE associated Golgi protein
Tpau_0515	COG4129	membrane
Tpau_0517	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Tpau_0520	COG0745	RESPONSE REGULATOR receiver
Tpau_0521	COG2205	protein histidine kinase activity
Tpau_0522	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Tpau_0523	COG1181	Belongs to the D-alanine--D-alanine ligase family
Tpau_0526	COG2814	Major facilitator Superfamily
Tpau_0527	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Tpau_0543	COG1690	Belongs to the RtcB family
Tpau_0550	COG0477	Major facilitator Superfamily
Tpau_0553	COG2027	D-alanyl-D-alanine carboxypeptidase
Tpau_0555	COG0037	tRNA processing
Tpau_0559	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tpau_0560	COG0302	gtp cyclohydrolase
Tpau_0561	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Tpau_0567	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Tpau_0568	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Tpau_0569	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Tpau_0571	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Tpau_0573	COG0542	response to heat
Tpau_0576	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Tpau_0580	COG1902	pentaerythritol trinitrate reductase activity
Tpau_0580	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tpau_0582	COG4221	oxidoreductase activity
Tpau_0583	COG2072	flavoprotein involved in K transport
Tpau_0587	COG0596	Alpha beta hydrolase
Tpau_0588	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Tpau_0589	COG4221	oxidoreductase activity
Tpau_0590	COG1309	transcriptional regulator
Tpau_0593	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0596	COG0288	reversible hydration of carbon dioxide
Tpau_0598	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Tpau_0599	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Tpau_0602	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Tpau_0605	COG0215	cysteine-tRNA ligase activity
Tpau_0606	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Tpau_0608	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Tpau_0610	COG1121	(ABC) transporter
Tpau_0615	COG3485	protocatechuate 3,4-dioxygenase
Tpau_0616	COG3485	protocatechuate 3,4-dioxygenase
Tpau_0617	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Tpau_0618	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Tpau_0621	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Tpau_0622	COG1414	Transcriptional regulator
Tpau_0623	COG2814	Major facilitator Superfamily
Tpau_0626	COG2267	carboxylic ester hydrolase activity
Tpau_0627	COG0438	transferase activity, transferring glycosyl groups
Tpau_0629	COG0477	Major facilitator Superfamily
Tpau_0634	COG0477	Major facilitator Superfamily
Tpau_0635	COG0667	Aldo Keto reductase
Tpau_0637	COG2318	DinB family
Tpau_0639	COG1119	ATPase activity
Tpau_0640	COG4106	trans-aconitate 2-methyltransferase activity
Tpau_0641	COG0583	DNA-binding transcription factor activity
Tpau_0642	COG2814	Major facilitator Superfamily
Tpau_0643	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_0646	COG1136	(ABC) transporter
Tpau_0646	COG0577	efflux transmembrane transporter activity
Tpau_0647	COG2197	response regulator
Tpau_0649	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Tpau_0651	COG0588	phosphoglycerate mutase activity
Tpau_0653	COG5002	protein histidine kinase activity
Tpau_0660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Tpau_0665	COG0560	Phosphoserine phosphatase
Tpau_0667	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Tpau_0668	COG0181	hydroxymethylbilane synthase activity
Tpau_0674	COG2608	mercury ion transmembrane transporter activity
Tpau_0676	COG2409	Drug exporters of the RND superfamily
Tpau_0680	COG0154	amidase activity
Tpau_0681	COG2957	Belongs to the agmatine deiminase family
Tpau_0684	COG2272	Belongs to the type-B carboxylesterase lipase family
Tpau_0685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Tpau_0687	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Tpau_0688	COG0406	alpha-ribazole phosphatase activity
Tpau_0690	COG0785	Cytochrome C biogenesis protein
Tpau_0692	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Tpau_0695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Tpau_0697	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Tpau_0702	COG1960	acyl-CoA dehydrogenase activity
Tpau_0709	COG3629	intracellular signal transduction
Tpau_0719	COG1250	3-hydroxyacyl-CoA dehydrogenase
Tpau_0720	COG4948	Mandelate Racemase Muconate Lactonizing
Tpau_0724	COG2409	Drug exporters of the RND superfamily
Tpau_0725	COG1937	Protein conserved in bacteria
Tpau_0726	COG3268	Saccharopine dehydrogenase
Tpau_0729	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Tpau_0731	COG0438	transferase activity, transferring glycosyl groups
Tpau_0732	COG2226	methyltransferase
Tpau_0734	COG0501	Belongs to the peptidase M48B family
Tpau_0736	COG1666	GTP binding
Tpau_0738	COG2030	dehydratase
Tpau_0739	COG2030	dehydratase
Tpau_0740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Tpau_0742	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Tpau_0743	COG0081	regulation of translation
Tpau_0753	COG0085	RNA polymerase activity
Tpau_0760	COG4948	Mandelate Racemase Muconate Lactonizing
Tpau_0761	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0763	COG2186	Transcriptional regulator
Tpau_0770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Tpau_0773	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_0775	COG0183	Belongs to the thiolase family
Tpau_0778	COG1073	alpha beta
Tpau_0779	COG2376	Dihydroxyacetone kinase
Tpau_0784	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tpau_0786	COG2972	Histidine kinase
Tpau_0786	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Tpau_0788	COG0640	Transcriptional regulator
Tpau_0790	COG0765	amino acid transport
Tpau_0791	COG1126	abc transporter atp-binding protein
Tpau_0794	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Tpau_0795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Tpau_0795	COG1263	PTS System
Tpau_0797	COG2190	(PTS) system
Tpau_0797	COG1263	PTS System
Tpau_0797	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Tpau_0809	COG1061	Type III restriction enzyme res subunit
Tpau_0814	COG4941	Belongs to the sigma-70 factor family
Tpau_0817	COG0315	cyclic pyranopterin monophosphate synthase activity
Tpau_0818	COG0521	Mo-molybdopterin cofactor biosynthetic process
Tpau_0818	COG0315	cyclic pyranopterin monophosphate synthase activity
Tpau_0820	COG1819	glycosyl
Tpau_0823	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Tpau_0825	COG1278	Cold shock
Tpau_0828	COG2814	Major facilitator Superfamily
Tpau_0839	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Tpau_0841	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Tpau_0843	COG1953	Uracil, thiamine, allantoin
Tpau_0844	COG2814	Major facilitator Superfamily
Tpau_0847	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Tpau_0851	COG4221	oxidoreductase activity
Tpau_0856	COG0545	Peptidyl-prolyl cis-trans isomerase
Tpau_0861	COG0656	L-ascorbic acid biosynthetic process
Tpau_0863	COG1404	Belongs to the peptidase S8 family
Tpau_0865	COG1674	ftsk spoiiie
Tpau_0869	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Tpau_0871	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tpau_0872	COG0546	phosphoglycolate phosphatase activity
Tpau_0878	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Tpau_0882	COG2154	pterin-4-alpha-carbinolamine dehydratase
Tpau_0883	COG1214	PFAM Peptidase M22, glycoprotease
Tpau_0883	COG0456	acetyltransferase
Tpau_0885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Tpau_0889	COG2207	Transcriptional regulator
Tpau_0898	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Tpau_0899	COG0459	protein refolding
Tpau_0900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_0907	COG0516	GMP reductase activity
Tpau_0910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Tpau_0910	COG0519	Catalyzes the synthesis of GMP from XMP
Tpau_0915	COG2197	response regulator
Tpau_0916	COG2815	serine threonine protein kinase
Tpau_0916	COG0515	serine threonine protein kinase
Tpau_0918	COG0833	amino acid
Tpau_0931	COG1742	UPF0060 membrane protein
Tpau_0937	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Tpau_0939	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Tpau_0941	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Tpau_0944	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Tpau_0945	COG2814	Major facilitator Superfamily
Tpau_0948	COG0708	Exodeoxyribonuclease III
Tpau_0949	COG0180	Tryptophanyl-tRNA synthetase
Tpau_0952	COG1686	Belongs to the peptidase S11 family
Tpau_0964	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Tpau_0967	COG2009	succinate dehydrogenase
Tpau_0970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tpau_0972	COG2197	response regulator
Tpau_0975	COG2207	Transcriptional regulator
Tpau_0982	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tpau_0986	COG1473	amidohydrolase
Tpau_0986	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Tpau_0990	COG1595	DNA-templated transcription, initiation
Tpau_0992	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Tpau_0995	COG1349	DNA-binding transcription factor activity
Tpau_0998	COG3250	beta-galactosidase activity
Tpau_1000	COG1175	transmembrane transport
Tpau_1002	COG3842	ATPase activity
Tpau_1005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Tpau_1006	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Tpau_1009	COG2197	response regulator
Tpau_1011	COG0477	Major facilitator Superfamily
Tpau_1014	COG1201	RNA secondary structure unwinding
Tpau_1015	COG2272	Belongs to the type-B carboxylesterase lipase family
Tpau_1017	COG1960	acyl-CoA dehydrogenase activity
Tpau_1020	COG0431	NADPH-dependent FMN reductase
Tpau_1021	COG1396	sequence-specific DNA binding
Tpau_1031	COG4770	biotin carboxylase activity
Tpau_1043	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tpau_1044	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Tpau_1044	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Tpau_1046	COG0745	RESPONSE REGULATOR receiver
Tpau_1047	COG2205	protein histidine kinase activity
Tpau_1049	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Tpau_1053	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tpau_1061	COG1316	TRANSCRIPTIONal
Tpau_1062	COG1091	dTDP-4-dehydrorhamnose reductase activity
Tpau_1064	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Tpau_1066	COG4122	O-methyltransferase activity
Tpau_1067	COG1595	DNA-templated transcription, initiation
Tpau_1068	COG5662	AntiSigma factor
Tpau_1070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tpau_1076	COG0745	RESPONSE REGULATOR receiver
Tpau_1077	COG5002	protein histidine kinase activity
Tpau_1078	COG5401	PFAM Sporulation and spore germination
Tpau_1080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Tpau_1081	COG0653	protein targeting
Tpau_1095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Tpau_1096	COG1162	GTPase activity
Tpau_1097	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Tpau_1100	COG2135	peptidase activity
Tpau_1103	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_1104	COG4221	oxidoreductase activity
Tpau_1105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Tpau_1107	COG1595	DNA-templated transcription, initiation
Tpau_1111	COG1597	lipid kinase activity
Tpau_1113	COG0406	alpha-ribazole phosphatase activity
Tpau_1114	COG1192	Involved in chromosome partitioning
Tpau_1118	COG0513	Belongs to the DEAD box helicase family
Tpau_1120	COG1309	transcriptional regulator
Tpau_1124	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_1130	COG0596	Alpha beta hydrolase
Tpau_1132	COG0210	DNA helicase
Tpau_1134	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_1138	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Tpau_1139	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_1142	COG1309	transcriptional regulator
Tpau_1145	COG0747	negative chemotaxis
Tpau_1146	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Tpau_1148	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Tpau_1150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Tpau_1153	COG3220	belongs to the UPF0276 family
Tpau_1159	COG2239	Acts as a magnesium transporter
Tpau_1160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tpau_1161	COG1611	Belongs to the LOG family
Tpau_1162	COG1611	Belongs to the LOG family
Tpau_1164	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Tpau_1165	COG0463	Glycosyl transferase, family 2
Tpau_1167	COG0789	Transcriptional regulator
Tpau_1174	COG0297	glycogen (starch) synthase activity
Tpau_1175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Tpau_1177	COG1280	lysine exporter protein (LysE YggA)
Tpau_1180	COG0300	oxidoreductase activity
Tpau_1187	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tpau_1189	COG1482	cell wall glycoprotein biosynthetic process
Tpau_1191	COG0531	amino acid
Tpau_1192	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Tpau_1195	COG2239	Acts as a magnesium transporter
Tpau_1207	COG0598	Magnesium transport protein CorA
Tpau_1211	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tpau_1211	COG0567	Dehydrogenase, E1 component
Tpau_1213	COG0824	Thioesterase
Tpau_1215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Tpau_1220	COG2814	Major facilitator Superfamily
Tpau_1222	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Tpau_1228	COG0018	arginyl-trna synthetase
Tpau_1230	COG0460	homoserine dehydrogenase
Tpau_1231	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Tpau_1232	COG0083	homoserine kinase activity
Tpau_1235	COG0254	rRNA binding
Tpau_1236	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Tpau_1237	COG2890	protein-(glutamine-N5) methyltransferase activity
Tpau_1245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_1246	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_1247	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Tpau_1249	COG0356	it plays a direct role in the translocation of protons across the membrane
Tpau_1250	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Tpau_1253	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Tpau_1254	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Tpau_1255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Tpau_1261	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Tpau_1265	COG0183	Belongs to the thiolase family
Tpau_1271	COG0395	ABC-type sugar transport system, permease component
Tpau_1273	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_1277	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tpau_1278	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Tpau_1279	COG0366	Alpha amylase catalytic
Tpau_1281	COG0583	DNA-binding transcription factor activity
Tpau_1285	COG1335	isochorismatase
Tpau_1286	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Tpau_1294	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Tpau_1295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Tpau_1296	COG1316	TRANSCRIPTIONal
Tpau_1310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Tpau_1315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Tpau_1317	COG0439	Biotin carboxylase
Tpau_1321	COG1960	acyl-CoA dehydrogenase activity
Tpau_1324	COG0583	DNA-binding transcription factor activity
Tpau_1329	COG1960	acyl-CoA dehydrogenase activity
Tpau_1330	COG3402	PFAM membrane-flanked domain
Tpau_1331	COG3428	Bacterial PH domain
Tpau_1334	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Tpau_1336	COG1131	(ABC) transporter
Tpau_1339	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Tpau_1340	COG0433	COG0433 Predicted ATPase
Tpau_1341	COG0300	oxidoreductase activity
Tpau_1342	COG2259	Doxx family
Tpau_1344	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tpau_1344	COG1902	pentaerythritol trinitrate reductase activity
Tpau_1349	COG2851	Citrate transporter
Tpau_1350	COG3290	protein histidine kinase activity
Tpau_1351	COG4565	transcriptional regulatory protein
Tpau_1357	COG0673	inositol 2-dehydrogenase activity
Tpau_1359	COG1172	Belongs to the binding-protein-dependent transport system permease family
Tpau_1361	COG0673	inositol 2-dehydrogenase activity
Tpau_1362	COG1082	Xylose isomerase domain protein TIM barrel
Tpau_1365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tpau_1368	COG3718	enzyme involved in inositol metabolism
Tpau_1369	COG3962	Belongs to the TPP enzyme family
Tpau_1379	COG2146	nitrite reductase [NAD(P)H] activity
Tpau_1379	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Tpau_1380	COG2146	nitrite reductase [NAD(P)H] activity
Tpau_1380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Tpau_1381	COG0243	molybdopterin cofactor binding
Tpau_1382	COG0604	alcohol dehydrogenase
Tpau_1382	COG3321	synthase
Tpau_1385	COG2902	Dehydrogenase
Tpau_1386	COG0824	Thioesterase
Tpau_1392	COG5001	Diguanylate cyclase
Tpau_1395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Tpau_1396	COG3012	SEC-C Motif Domain Protein
Tpau_1399	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Tpau_1400	COG0501	Belongs to the peptidase M48B family
Tpau_1410	COG2197	response regulator
Tpau_1415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tpau_1416	COG0531	amino acid
Tpau_1418	COG1396	sequence-specific DNA binding
Tpau_1419	COG1024	Enoyl-CoA hydratase
Tpau_1423	COG4974	Belongs to the 'phage' integrase family
Tpau_1424	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Tpau_1441	COG2259	Doxx family
Tpau_1443	COG0531	amino acid
Tpau_1447	COG2224	Isocitrate lyase
Tpau_1448	COG3340	Belongs to the peptidase S51 family
Tpau_1450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_1451	COG1120	ATPase activity
Tpau_1453	COG1396	sequence-specific DNA binding
Tpau_1454	COG3135	benzoate transporter
Tpau_1460	COG0544	peptidyl-prolyl cis-trans isomerase activity
Tpau_1461	COG0740	serine-type endopeptidase activity
Tpau_1462	COG0740	serine-type endopeptidase activity
Tpau_1465	COG0488	(ABC) transporter
Tpau_1468	COG0525	valine-tRNA ligase activity
Tpau_1469	COG0285	dihydrofolate synthase activity
Tpau_1472	COG1530	ribonuclease E activity
Tpau_1474	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Tpau_1475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tpau_1477	COG3396	Phenylacetate-CoA oxygenase
Tpau_1478	COG0740	serine-type endopeptidase activity
Tpau_1479	COG0740	serine-type endopeptidase activity
Tpau_1483	COG0477	Major facilitator Superfamily
Tpau_1483	COG2814	Major facilitator Superfamily
Tpau_1489	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Tpau_1493	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Tpau_1494	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Tpau_1494	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tpau_1497	COG0174	glutamine synthetase
Tpau_1498	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Tpau_1501	COG0545	Peptidyl-prolyl cis-trans isomerase
Tpau_1510	COG0174	glutamine synthetase
Tpau_1513	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Tpau_1514	COG2814	Major facilitator Superfamily
Tpau_1515	COG0321	lipoyl(octanoyl) transferase activity
Tpau_1523	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Tpau_1524	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Tpau_1526	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Tpau_1534	COG0789	Transcriptional regulator
Tpau_1537	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Tpau_1540	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_1544	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tpau_1545	COG0066	3-isopropylmalate dehydratase activity
Tpau_1546	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Tpau_1547	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_1555	COG1917	Cupin 2, conserved barrel domain protein
Tpau_1557	COG0456	acetyltransferase
Tpau_1559	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Tpau_1562	COG0477	Major facilitator Superfamily
Tpau_1563	COG0742	ribosomal rna small subunit methyltransferase
Tpau_1564	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Tpau_1565	COG3599	regulation of cell shape
Tpau_1567	COG0571	ribonuclease III activity
Tpau_1571	COG1254	Belongs to the acylphosphatase family
Tpau_1573	COG0754	glutathionylspermidine amidase activity
Tpau_1574	COG3766	membrane
Tpau_1575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Tpau_1576	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Tpau_1577	COG0438	transferase activity, transferring glycosyl groups
Tpau_1579	COG0438	transferase activity, transferring glycosyl groups
Tpau_1580	COG0438	transferase activity, transferring glycosyl groups
Tpau_1587	COG1196	nuclear chromosome segregation
Tpau_1589	COG0326	Molecular chaperone. Has ATPase activity
Tpau_1593	COG3665	Urea carboxylase-associated protein
Tpau_1594	COG1984	allophanate hydrolase subunit 2
Tpau_1598	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_1600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tpau_1610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Tpau_1616	COG0076	glutamate decarboxylase activity
Tpau_1617	COG0228	four-way junction DNA binding
Tpau_1619	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Tpau_1620	COG0336	Belongs to the RNA methyltransferase TrmD family
Tpau_1622	COG0745	RESPONSE REGULATOR receiver
Tpau_1630	COG0335	large ribosomal subunit rRNA binding
Tpau_1632	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Tpau_1636	COG3842	ATPase activity
Tpau_1638	COG0395	ABC-type sugar transport system, permease component
Tpau_1641	COG0792	nuclease activity
Tpau_1642	COG0606	chelatase, subunit chli
Tpau_1649	COG0477	Major facilitator Superfamily
Tpau_1652	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Tpau_1653	COG2011	ABC-type metal ion transport system permease component
Tpau_1654	COG4974	Belongs to the 'phage' integrase family
Tpau_1658	COG0501	Belongs to the peptidase M48B family
Tpau_1659	COG2814	Major facilitator Superfamily
Tpau_1660	COG1823	symporter activity
Tpau_1663	COG2272	Belongs to the type-B carboxylesterase lipase family
Tpau_1668	COG0052	Belongs to the universal ribosomal protein uS2 family
Tpau_1669	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Tpau_1674	COG0233	cytoplasmic translational termination
Tpau_1678	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Tpau_1682	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Tpau_1683	COG0750	zinc metalloprotease
Tpau_1684	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Tpau_1690	COG0768	penicillin binding
Tpau_1693	COG1492	cobalamin metabolic process
Tpau_1694	COG2267	carboxylic ester hydrolase activity
Tpau_1698	COG0579	oxidoreductase
Tpau_1703	COG1648	precorrin-2 dehydrogenase activity
Tpau_1703	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Tpau_1706	COG3022	response to hydroperoxide
Tpau_1707	COG0442	prolyl-tRNA aminoacylation
Tpau_1708	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
Tpau_1715	COG0481	GTPase activity
Tpau_1715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Tpau_1717	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Tpau_1718	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Tpau_1727	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Tpau_1729	COG0372	Belongs to the citrate synthase family
Tpau_1732	COG1321	iron dependent repressor
Tpau_1735	COG3540	Alkaline phosphatase
Tpau_1737	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Tpau_1737	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Tpau_1738	COG1185	polyribonucleotide nucleotidyltransferase activity
Tpau_1739	COG0612	Peptidase, M16
Tpau_1743	COG0686	Belongs to the AlaDH PNT family
Tpau_1744	COG1522	sequence-specific DNA binding
Tpau_1746	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Tpau_1747	COG1741	Belongs to the pirin family
Tpau_1751	COG2409	Drug exporters of the RND superfamily
Tpau_1752	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tpau_1760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Tpau_1762	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Tpau_1763	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Tpau_1772	COG0861	Integral membrane protein TerC family
Tpau_1773	COG2890	protein-(glutamine-N5) methyltransferase activity
Tpau_1774	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Tpau_1776	COG1546	Belongs to the CinA family
Tpau_1776	COG1058	Belongs to the CinA family
Tpau_1777	COG1396	sequence-specific DNA binding
Tpau_1785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Tpau_1786	COG2137	regulation of response to DNA damage stimulus
Tpau_1788	COG0765	amino acid transport
Tpau_1789	COG0765	amino acid transport
Tpau_1790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Tpau_1791	COG1126	abc transporter atp-binding protein
Tpau_1793	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Tpau_1796	COG1196	nuclear chromosome segregation
Tpau_1798	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Tpau_1799	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Tpau_1800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Tpau_1806	COG1960	acyl-CoA dehydrogenase activity
Tpau_1807	COG1960	acyl-CoA dehydrogenase activity
Tpau_1808	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Tpau_1810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Tpau_1811	COG1643	Atp-dependent helicase
Tpau_1814	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Tpau_1832	COG0123	including yeast histone deacetylase and acetoin utilization protein
Tpau_1833	COG0045	succinate-CoA ligase (ADP-forming) activity
Tpau_1842	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_1845	COG3590	peptidase
Tpau_1847	COG4303	Ethanolamine ammonia lyase large subunit
Tpau_1848	COG0531	amino acid
Tpau_1853	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_1856	COG1011	Hydrolase
Tpau_1857	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_1861	COG1960	acyl-CoA dehydrogenase activity
Tpau_1862	COG1960	acyl-CoA dehydrogenase activity
Tpau_1864	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_1865	COG0477	Major facilitator Superfamily
Tpau_1868	COG3012	SEC-C Motif Domain Protein
Tpau_1872	COG4770	biotin carboxylase activity
Tpau_1875	COG4585	Histidine kinase
Tpau_1884	COG0756	dUTP diphosphatase activity
Tpau_1888	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Tpau_1889	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Tpau_1895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Tpau_1898	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tpau_1898	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tpau_1900	COG1937	Protein conserved in bacteria
Tpau_1906	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tpau_1907	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Tpau_1908	COG0706	membrane insertase activity
Tpau_1910	COG0346	lactoylglutathione lyase activity
Tpau_1913	COG1216	Glycosyl transferase, family 2
Tpau_1914	COG1309	transcriptional regulator
Tpau_1919	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Tpau_1922	COG1560	Kdo2-lipid A biosynthetic process
Tpau_1923	COG0438	transferase activity, transferring glycosyl groups
Tpau_1924	COG0494	nUDIX hydrolase
Tpau_1926	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Tpau_1929	COG1946	Acyl-CoA thioesterase
Tpau_1930	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Tpau_1934	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Tpau_1936	COG2255	four-way junction helicase activity
Tpau_1938	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Tpau_1940	COG0514	ATP-dependent DNA helicase (RecQ)
Tpau_1943	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Tpau_1945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Tpau_1947	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_1950	COG0124	histidyl-tRNA synthetase
Tpau_1953	COG0640	Transcriptional regulator
Tpau_1955	COG0523	cobalamin synthesis protein
Tpau_1963	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Tpau_1967	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Tpau_1968	COG0444	Belongs to the ABC transporter superfamily
Tpau_1969	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tpau_1975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Tpau_1976	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Tpau_1977	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Tpau_1978	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Tpau_1982	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_1988	COG0765	amino acid transport
Tpau_1989	COG2197	response regulator
Tpau_1990	COG4585	Histidine kinase
Tpau_1994	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_1995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_1999	COG0156	8-amino-7-oxononanoate synthase activity
Tpau_2000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Tpau_2001	COG0671	phosphoesterase, PA-phosphatase related
Tpau_2002	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Tpau_2006	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_2007	COG1752	Esterase of the alpha-beta hydrolase superfamily
Tpau_2010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Tpau_2015	COG0745	RESPONSE REGULATOR receiver
Tpau_2016	COG5002	protein histidine kinase activity
Tpau_2023	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Tpau_2024	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Tpau_2025	COG0131	Imidazoleglycerol-phosphate dehydratase
Tpau_2026	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Tpau_2027	COG1953	Uracil, thiamine, allantoin
Tpau_2030	COG3257	ureidoglycine aminohydrolase activity
Tpau_2032	COG1414	Transcriptional regulator
Tpau_2034	COG1024	Enoyl-CoA hydratase
Tpau_2035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Tpau_2035	COG0045	succinate-CoA ligase (ADP-forming) activity
Tpau_2035	COG1042	CoA-binding domain protein
Tpau_2036	COG1024	Enoyl-CoA hydratase
Tpau_2037	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Tpau_2040	COG0483	inositol monophosphate 1-phosphatase activity
Tpau_2041	COG0107	imidazoleglycerol-phosphate synthase activity
Tpau_2042	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Tpau_2044	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Tpau_2047	COG2971	BadF BadG BcrA BcrD
Tpau_2048	COG2814	Major facilitator Superfamily
Tpau_2049	COG2188	Transcriptional regulator
Tpau_2052	COG0765	amino acid transport
Tpau_2055	COG0159	tryptophan synthase activity
Tpau_2056	COG5002	protein histidine kinase activity
Tpau_2056	COG5001	Diguanylate cyclase
Tpau_2056	COG3447	MASE1 domain protein
Tpau_2057	COG5001	Diguanylate cyclase
Tpau_2059	COG0488	(ABC) transporter
Tpau_2060	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_2063	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Tpau_2067	COG0584	glycerophosphoryl diester phosphodiesterase
Tpau_2072	COG3842	ATPase activity
Tpau_2074	COG1309	transcriptional regulator
Tpau_2075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Tpau_2077	COG0791	NLP P60 protein
Tpau_2077	COG3883	PFAM NLP P60 protein
Tpau_2078	COG0714	Associated with various cellular activities
Tpau_2082	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Tpau_2095	COG0583	DNA-binding transcription factor activity
Tpau_2100	COG3573	Dehydrogenase
Tpau_2102	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tpau_2109	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Tpau_2112	COG5001	Diguanylate cyclase
Tpau_2114	COG0531	amino acid
Tpau_2116	COG1960	acyl-CoA dehydrogenase activity
Tpau_2124	COG3265	gluconokinase activity
Tpau_2128	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tpau_2133	COG1968	undecaprenyl-diphosphatase activity
Tpau_2134	COG0583	DNA-binding transcription factor activity
Tpau_2140	COG0215	cysteine-tRNA ligase activity
Tpau_2144	COG1410	methionine synthase
Tpau_2144	COG0646	methionine synthase
Tpau_2145	COG0737	Belongs to the 5'-nucleotidase family
Tpau_2146	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tpau_2149	COG0140	phosphoribosyl-ATP diphosphatase activity
Tpau_2150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Tpau_2153	COG1222	aaa ATPase
Tpau_2154	COG1131	(ABC) transporter
Tpau_2154	COG0842	Transport permease protein
Tpau_2154	COG1716	ATPase activity
Tpau_2160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Tpau_2162	COG0733	neurotransmitter:sodium symporter activity
Tpau_2167	COG2378	regulation of single-species biofilm formation
Tpau_2168	COG2378	regulation of single-species biofilm formation
Tpau_2169	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tpau_2175	COG0477	Major facilitator Superfamily
Tpau_2177	COG0300	oxidoreductase activity
Tpau_2183	COG0596	Alpha beta hydrolase
Tpau_2186	COG2814	Major facilitator Superfamily
Tpau_2188	COG1396	sequence-specific DNA binding
Tpau_2193	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Tpau_2198	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Tpau_2200	COG0463	Glycosyl transferase, family 2
Tpau_2206	COG2072	flavoprotein involved in K transport
Tpau_2211	COG1454	alcohol dehydrogenase
Tpau_2216	COG2186	Transcriptional regulator
Tpau_2217	COG2807	transmembrane transport
Tpau_2219	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Tpau_2225	COG1250	3-hydroxyacyl-CoA dehydrogenase
Tpau_2227	COG2124	cytochrome p450
Tpau_2228	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Tpau_2230	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_2231	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Tpau_2233	COG0798	PFAM Bile acid sodium symporter
Tpau_2249	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_2250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_2262	COG2354	Protein conserved in bacteria
Tpau_2267	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Tpau_2270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Tpau_2271	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Tpau_2272	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Tpau_2276	COG1063	alcohol dehydrogenase
Tpau_2287	COG2268	Band 7 protein
Tpau_2290	COG1309	transcriptional regulator
Tpau_2291	COG1819	glycosyl
Tpau_2294	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Tpau_2295	COG1074	ATP-dependent DNA helicase activity
Tpau_2300	COG4762	Protein conserved in bacteria
Tpau_2305	COG1695	Transcriptional regulator
Tpau_2317	COG1253	flavin adenine dinucleotide binding
Tpau_2320	COG0739	heme binding
Tpau_2321	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_2322	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Tpau_2334	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tpau_2334	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tpau_2342	COG0653	protein targeting
Tpau_2343	COG2234	aminopeptidase activity
Tpau_2346	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Tpau_2348	COG0746	molybdenum cofactor guanylyltransferase activity
Tpau_2349	COG0596	Alpha beta hydrolase
Tpau_2353	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Tpau_2354	COG1309	transcriptional regulator
Tpau_2355	COG0300	oxidoreductase activity
Tpau_2362	COG2365	Tyrosine phosphatase family
Tpau_2369	COG1160	GTP binding
Tpau_2370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Tpau_2372	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Tpau_2373	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Tpau_2376	COG0494	nUDIX hydrolase
Tpau_2382	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Tpau_2385	COG0647	UMP catabolic process
Tpau_2388	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Tpau_2390	COG2835	tetraacyldisaccharide 4'-kinase activity
Tpau_2393	COG1131	(ABC) transporter
Tpau_2395	COG1309	transcriptional regulator
Tpau_2396	COG0165	Argininosuccinate lyase
Tpau_2397	COG0137	argininosuccinate synthase activity
Tpau_2398	COG1438	arginine binding
Tpau_2399	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Tpau_2400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Tpau_2401	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Tpau_2402	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Tpau_2408	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tpau_2408	COG0072	phenylalanine-tRNA ligase activity
Tpau_2409	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Tpau_2414	COG2197	response regulator
Tpau_2417	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Tpau_2423	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tpau_2425	COG3973	AAA domain
Tpau_2433	COG0237	dephospho-CoA kinase activity
Tpau_2433	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Tpau_2435	COG0539	negative regulation of cytoplasmic translation
Tpau_2436	COG2226	methyltransferase
Tpau_2448	COG4260	virion core protein, lumpy skin disease virus
Tpau_2449	COG3422	double-strand break repair
Tpau_2454	COG0477	Major facilitator Superfamily
Tpau_2459	COG1902	pentaerythritol trinitrate reductase activity
Tpau_2460	COG0435	Glutathione S-transferase
Tpau_2471	COG3328	transposase activity
Tpau_2482	COG3243	poly(R)-hydroxyalkanoic acid synthase
Tpau_2486	COG0705	Rhomboid family
Tpau_2489	COG1946	Acyl-CoA thioesterase
Tpau_2491	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Tpau_2496	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tpau_2499	COG1960	acyl-CoA dehydrogenase activity
Tpau_2501	COG1846	Transcriptional regulator
Tpau_2502	COG4977	sequence-specific DNA binding
Tpau_2504	COG2151	metal-sulfur cluster biosynthetic enzyme
Tpau_2507	COG0396	ATPase activity
Tpau_2512	COG1131	(ABC) transporter
Tpau_2518	COG1309	transcriptional regulator
Tpau_2521	COG0109	protoheme IX farnesyltransferase activity
Tpau_2523	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Tpau_2526	COG0363	glucosamine-6-phosphate deaminase activity
Tpau_2533	COG1960	acyl-CoA dehydrogenase activity
Tpau_2535	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
Tpau_2536	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Tpau_2537	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Tpau_2538	COG0149	triose-phosphate isomerase activity
Tpau_2539	COG0126	phosphoglycerate kinase activity
Tpau_2540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Tpau_2542	COG1481	regulation of sporulation
Tpau_2544	COG1660	Displays ATPase and GTPase activities
Tpau_2546	COG0405	Gamma-glutamyltransferase
Tpau_2550	COG0322	excinuclease ABC activity
Tpau_2552	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_2556	COG3104	oligopeptide transport
Tpau_2558	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_2560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Tpau_2561	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Tpau_2561	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Tpau_2567	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Tpau_2568	COG0242	peptide deformylase activity
Tpau_2573	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Tpau_2575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Tpau_2577	COG1758	RNA polymerase activity
Tpau_2580	COG0284	orotidine-5'-phosphate decarboxylase activity
Tpau_2582	COG0505	Belongs to the CarA family
Tpau_2590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Tpau_2591	COG0006	proline dipeptidase activity
Tpau_2612	COG0297	glycogen (starch) synthase activity
Tpau_2613	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tpau_2614	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Tpau_2615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Tpau_2617	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Tpau_2628	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Tpau_2631	COG0252	asparaginase activity
Tpau_2636	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Tpau_2640	COG1799	cell septum assembly
Tpau_2641	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Tpau_2644	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Tpau_2645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Tpau_2646	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Tpau_2648	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Tpau_2649	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Tpau_2650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Tpau_2652	COG0768	penicillin binding
Tpau_2654	COG0275	rRNA processing
Tpau_2655	COG2001	Belongs to the MraZ family
Tpau_2662	COG0142	geranyltranstransferase activity
Tpau_2663	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Tpau_2666	COG4604	ABC transporter, ATP-binding protein
Tpau_2670	COG2357	RelA SpoT domain protein
Tpau_2672	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Tpau_2675	COG1940	carbohydrate kinase activity
Tpau_2681	COG0438	transferase activity, transferring glycosyl groups
Tpau_2689	COG0442	prolyl-tRNA aminoacylation
Tpau_2690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Tpau_2697	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_2700	COG4948	Mandelate Racemase Muconate Lactonizing
Tpau_2702	COG1053	succinate dehydrogenase
Tpau_2704	COG0179	Fumarylacetoacetate (FAA) hydrolase
Tpau_2710	COG0328	RNA-DNA hybrid ribonuclease activity
Tpau_2710	COG0406	alpha-ribazole phosphatase activity
Tpau_2712	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Tpau_2712	COG3323	Protein of unknown function (DUF1653)
Tpau_2722	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Tpau_2725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Tpau_2737	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Tpau_2739	COG0358	DNA primase activity
Tpau_2740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Tpau_2741	COG1278	Cold shock
Tpau_2743	COG0423	glycine-tRNA ligase activity
Tpau_2750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Tpau_2751	COG1846	Transcriptional regulator
Tpau_2752	COG1764	response to oxidative stress
Tpau_2756	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Tpau_2757	COG1381	Involved in DNA repair and RecF pathway recombination
Tpau_2761	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Tpau_2765	COG0484	heat shock protein binding
Tpau_2766	COG1420	regulation of RNA biosynthetic process
Tpau_2772	COG0175	sulfate reduction
Tpau_2776	COG4552	Acetyltransferase involved in intracellular survival and related
Tpau_2777	COG3842	ATPase activity
Tpau_2778	COG4208	sulfate ABC transporter
Tpau_2780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Tpau_2783	COG3387	PFAM Glycoside hydrolase 15-related
Tpau_2787	COG2070	2-Nitropropane dioxygenase
Tpau_2790	COG0481	GTPase activity
Tpau_2792	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Tpau_2797	COG1305	Transglutaminase-like
Tpau_2799	COG2308	Evidence 4 Homologs of previously reported genes of
Tpau_2800	COG0268	Binds directly to 16S ribosomal RNA
Tpau_2803	COG1555	photosystem II stabilization
Tpau_2803	COG1596	polysaccharide export
Tpau_2804	COG1307	EDD domain protein, DegV family
Tpau_2805	COG2755	lipolytic protein G-D-S-L family
Tpau_2806	COG0406	alpha-ribazole phosphatase activity
Tpau_2807	COG0799	negative regulation of ribosome biogenesis
Tpau_2808	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Tpau_2810	COG0542	response to heat
Tpau_2813	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Tpau_2827	COG1960	acyl-CoA dehydrogenase activity
Tpau_2828	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tpau_2831	COG1024	Enoyl-CoA hydratase
Tpau_2832	COG1309	transcriptional regulator
Tpau_2834	COG1461	Dihydroxyacetone kinase
Tpau_2835	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Tpau_2841	COG1181	Belongs to the D-alanine--D-alanine ligase family
Tpau_2842	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Tpau_2844	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Tpau_2847	COG0066	3-isopropylmalate dehydratase activity
Tpau_2848	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Tpau_2851	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Tpau_2853	COG0179	Fumarylacetoacetate (FAA) hydrolase
Tpau_2854	COG2271	Major facilitator Superfamily
Tpau_2855	COG0473	3-isopropylmalate dehydrogenase activity
Tpau_2858	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_2861	COG3396	Phenylacetate-CoA oxygenase
Tpau_2862	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Tpau_2863	COG0440	acetolactate synthase activity
Tpau_2866	COG0129	dihydroxy-acid dehydratase activity
Tpau_2867	COG2259	Doxx family
Tpau_2869	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tpau_2871	COG0205	6-phosphofructokinase activity
Tpau_2872	COG2197	response regulator
Tpau_2873	COG4585	Histidine kinase
Tpau_2876	COG1959	2 iron, 2 sulfur cluster binding
Tpau_2877	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Tpau_2880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tpau_2882	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_2884	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_2887	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Tpau_2891	COG2072	flavoprotein involved in K transport
Tpau_2892	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Tpau_2895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Tpau_2895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Tpau_2900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Tpau_2909	COG0482	sulfurtransferase activity
Tpau_2915	COG3590	peptidase
Tpau_2916	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Tpau_2918	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Tpau_2926	COG0110	maltose O-acetyltransferase activity
Tpau_2929	COG0024	Methionine aminopeptidase
Tpau_2932	COG0436	Aminotransferase
Tpau_2938	COG1119	ATPase activity
Tpau_2939	COG1523	belongs to the glycosyl hydrolase 13 family
Tpau_2940	COG0560	Phosphoserine phosphatase
Tpau_2940	COG3830	Belongs to the UPF0237 family
Tpau_2944	COG3396	Phenylacetate-CoA oxygenase
Tpau_2955	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_2958	COG1309	transcriptional regulator
Tpau_2961	COG2351	hydroxyisourate hydrolase activity
Tpau_2962	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Tpau_2965	COG2233	PERMEase
Tpau_2966	COG0402	S-adenosylhomocysteine deaminase activity
Tpau_2967	COG3835	regulator
Tpau_2968	COG2080	2 iron, 2 sulfur cluster binding
Tpau_2968	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Tpau_2969	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Tpau_2970	COG1780	Probably involved in ribonucleotide reductase function
Tpau_2972	COG0431	NADPH-dependent FMN reductase
Tpau_2979	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tpau_2984	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Tpau_2986	COG3708	Transcriptional regulator
Tpau_2986	COG2207	Transcriptional regulator
Tpau_2988	COG0640	Transcriptional regulator
Tpau_2998	COG4249	Peptidase C14 caspase catalytic subunit p20
Tpau_2999	COG3634	alkyl hydroperoxide reductase activity
Tpau_3000	COG0450	alkyl hydroperoxide reductase
Tpau_3004	COG2610	gluconate transmembrane transporter activity
Tpau_3005	COG0800	Aldolase
Tpau_3006	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Tpau_3009	COG1414	Transcriptional regulator
Tpau_3012	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Tpau_3014	COG3012	SEC-C Motif Domain Protein
Tpau_3020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Tpau_3021	COG2177	Part of the ABC transporter FtsEX involved in
Tpau_3022	COG2884	Cell division ATP-binding protein ftsE
Tpau_3024	COG0668	transmembrane transport
Tpau_3025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Tpau_3027	COG0483	inositol monophosphate 1-phosphatase activity
Tpau_3028	COG1960	acyl-CoA dehydrogenase activity
Tpau_3029	COG1960	acyl-CoA dehydrogenase activity
Tpau_3031	COG1388	LysM domain
Tpau_3032	COG2814	Major facilitator Superfamily
Tpau_3033	COG0730	response to heat
Tpau_3034	COG0110	maltose O-acetyltransferase activity
Tpau_3036	COG0584	glycerophosphoryl diester phosphodiesterase
Tpau_3037	COG1615	UPF0182 protein
Tpau_3039	COG3480	Lon protease (S16) C-terminal proteolytic domain
Tpau_3043	COG1960	acyl-CoA dehydrogenase activity
Tpau_3054	COG3842	ATPase activity
Tpau_3060	COG0738	Major facilitator superfamily
Tpau_3061	COG1609	Transcriptional regulator
Tpau_3064	COG0058	SHG alpha-glucan phosphorylase activity
Tpau_3069	COG1960	acyl-CoA dehydrogenase activity
Tpau_3071	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Tpau_3072	COG1131	(ABC) transporter
Tpau_3077	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tpau_3083	COG2249	NAD(P)H dehydrogenase (quinone) activity
Tpau_3099	COG2814	Major facilitator Superfamily
Tpau_3101	COG0012	GTP binding
Tpau_3105	COG1966	Carbon starvation protein
Tpau_3109	COG2169	Transcriptional regulator
Tpau_3109	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Tpau_3111	COG1322	Protein conserved in bacteria
Tpau_3116	COG1570	exodeoxyribonuclease VII activity
Tpau_3117	COG1722	exodeoxyribonuclease VII activity
Tpau_3124	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Tpau_3124	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Tpau_3128	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Tpau_3130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Tpau_3136	COG1116	anion transmembrane transporter activity
Tpau_3137	COG4521	taurine ABC transporter
Tpau_3138	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tpau_3141	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Tpau_3142	COG1331	Highly conserved protein containing a thioredoxin domain
Tpau_3143	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Tpau_3145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Tpau_3148	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Tpau_3158	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Tpau_3160	COG2076	Multidrug Resistance protein
Tpau_3165	COG0148	phosphopyruvate hydratase activity
Tpau_3169	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tpau_3170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tpau_3173	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Tpau_3174	COG1034	ATP synthesis coupled electron transport
Tpau_3175	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Tpau_3176	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tpau_3177	COG0839	Belongs to the complex I subunit 6 family
Tpau_3178	COG0713	ATP synthesis coupled electron transport
Tpau_3183	COG1309	transcriptional regulator
Tpau_3188	COG1073	alpha beta
Tpau_3190	COG3956	TIGRFAM MazG family protein
Tpau_3194	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Tpau_3196	COG1393	Belongs to the ArsC family
Tpau_3201	COG2837	iron assimilation
Tpau_3203	COG0542	response to heat
Tpau_3208	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
Tpau_3210	COG0193	aminoacyl-tRNA hydrolase activity
Tpau_3212	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Tpau_3214	COG1280	lysine exporter protein (LysE YggA)
Tpau_3225	COG0488	(ABC) transporter
Tpau_3229	COG3012	SEC-C Motif Domain Protein
Tpau_3230	COG0488	(ABC) transporter
Tpau_3231	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Tpau_3232	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Tpau_3233	COG3583	domain protein
Tpau_3234	COG0084	hydrolase, TatD family'
Tpau_3244	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Tpau_3245	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Tpau_3246	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Tpau_3251	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Tpau_3255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Tpau_3257	COG0596	Alpha beta hydrolase
Tpau_3258	COG5473	translation initiation factor activity
Tpau_3259	COG5473	translation initiation factor activity
Tpau_3263	COG1733	regulation of RNA biosynthetic process
Tpau_3264	COG3384	dioxygenase
Tpau_3266	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Tpau_3268	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Tpau_3269	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Tpau_3277	COG1970	mechanosensitive ion channel activity
Tpau_3283	COG0521	Mo-molybdopterin cofactor biosynthetic process
Tpau_3284	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tpau_3287	COG2860	membrane
Tpau_3289	COG0254	rRNA binding
Tpau_3291	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Tpau_3293	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Tpau_3294	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Tpau_3298	COG4867	von Willebrand factor, type A
Tpau_3302	COG0640	Transcriptional regulator
Tpau_3309	COG2814	Major facilitator Superfamily
Tpau_3315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Tpau_3316	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_3319	COG1960	acyl-CoA dehydrogenase activity
Tpau_3321	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Tpau_3323	COG1285	pathogenesis
Tpau_3324	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Tpau_3325	COG1116	anion transmembrane transporter activity
Tpau_3326	COG0739	heme binding
Tpau_3332	COG4424	Sulfotransferase
Tpau_3335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Tpau_3336	COG3119	arylsulfatase activity
Tpau_3338	COG0166	Belongs to the GPI family
Tpau_3343	COG2364	Membrane
Tpau_3344	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Tpau_3349	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Tpau_3350	COG1218	3'(2'),5'-bisphosphate nucleotidase
Tpau_3357	COG0328	RNA-DNA hybrid ribonuclease activity
Tpau_3359	COG1408	metallophosphoesterase
Tpau_3364	COG2072	flavoprotein involved in K transport
Tpau_3380	COG0101	tRNA pseudouridine synthase activity
Tpau_3382	COG0202	RNA polymerase activity
Tpau_3383	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Tpau_3384	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Tpau_3385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tpau_3386	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Tpau_3388	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Tpau_3389	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Tpau_3393	COG0789	Transcriptional regulator
Tpau_3394	COG1301	dicarboxylic acid transport
Tpau_3396	COG0563	adenylate kinase activity
Tpau_3398	COG0200	Binds to the 23S rRNA
Tpau_3399	COG1841	ribosomal large subunit assembly
Tpau_3400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Tpau_3401	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Tpau_3402	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Tpau_3406	COG0829	nickel cation binding
Tpau_3407	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Tpau_3408	COG0830	nickel cation binding
Tpau_3410	COG0832	Belongs to the urease beta subunit family
Tpau_3411	COG0831	urea catabolic process
Tpau_3418	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Tpau_3419	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tpau_3420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Tpau_3421	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Tpau_3424	COG0513	Belongs to the DEAD box helicase family
Tpau_3426	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Tpau_3427	COG0255	Belongs to the universal ribosomal protein uL29 family
Tpau_3428	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Tpau_3429	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Tpau_3431	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Tpau_3432	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tpau_3433	COG0089	rRNA binding
Tpau_3434	COG0088	Forms part of the polypeptide exit tunnel
Tpau_3435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Tpau_3436	COG0051	transcription antitermination factor activity, RNA binding
Tpau_3445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Tpau_3459	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_3466	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Tpau_3468	COG0049	tRNA binding
Tpau_3469	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Tpau_3472	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Tpau_3497	COG1131	(ABC) transporter
Tpau_3507	COG2197	response regulator
Tpau_3509	COG2132	Multicopper oxidase
Tpau_3513	COG2072	flavoprotein involved in K transport
Tpau_3516	COG0657	acetylesterase activity
Tpau_3517	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Tpau_3519	COG0477	Major facilitator Superfamily
Tpau_3520	COG1984	allophanate hydrolase subunit 2
Tpau_3522	COG1595	DNA-templated transcription, initiation
Tpau_3525	COG0438	transferase activity, transferring glycosyl groups
Tpau_3526	COG3842	ATPase activity
Tpau_3527	COG1653	transport
Tpau_3534	COG2197	response regulator
Tpau_3540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Tpau_3544	COG0456	acetyltransferase
Tpau_3545	COG0745	RESPONSE REGULATOR receiver
Tpau_3547	COG2897	thiosulfate sulfurtransferase activity
Tpau_3550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Tpau_3551	COG3145	DNA-N1-methyladenine dioxygenase activity
Tpau_3553	COG0745	RESPONSE REGULATOR receiver
Tpau_3554	COG0572	uridine kinase
Tpau_3561	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Tpau_3566	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Tpau_3567	COG4988	ABC transporter
Tpau_3568	COG1294	oxidase, subunit
Tpau_3572	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Tpau_3575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Tpau_3582	COG1090	epimerase
Tpau_3585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tpau_3588	COG5343	regulation of RNA biosynthetic process
Tpau_3591	COG1113	amino acid transport
Tpau_3595	COG1301	dicarboxylic acid transport
Tpau_3596	COG3290	protein histidine kinase activity
Tpau_3597	COG4565	transcriptional regulatory protein
Tpau_3602	COG0747	negative chemotaxis
Tpau_3605	COG0601	transmembrane transport
Tpau_3606	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3609	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Tpau_3610	COG3383	formate dehydrogenase (NAD+) activity
Tpau_3611	COG1113	amino acid transport
Tpau_3612	COG1362	aminopeptidase activity
Tpau_3613	COG0047	phosphoribosylformylglycinamidine synthase activity
Tpau_3614	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Tpau_3617	COG0386	Belongs to the glutathione peroxidase family
Tpau_3619	COG0477	Major facilitator Superfamily
Tpau_3622	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Tpau_3624	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Tpau_3630	COG5002	protein histidine kinase activity
Tpau_3631	COG0745	RESPONSE REGULATOR receiver
Tpau_3634	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Tpau_3638	COG1024	Enoyl-CoA hydratase
Tpau_3642	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Tpau_3644	COG1305	Transglutaminase-like
Tpau_3646	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Tpau_3653	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Tpau_3654	COG0788	formyltetrahydrofolate deformylase activity
Tpau_3655	COG0406	alpha-ribazole phosphatase activity
Tpau_3656	COG0596	Alpha beta hydrolase
Tpau_3660	COG2733	membrane
Tpau_3661	COG2326	polyphosphate kinase activity
Tpau_3663	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3664	COG0583	DNA-binding transcription factor activity
Tpau_3665	COG2226	methyltransferase
Tpau_3666	COG0492	ferredoxin-NADP+ reductase activity
Tpau_3668	COG2224	Isocitrate lyase
Tpau_3672	COG5285	phytanoyl-CoA dioxygenase
Tpau_3675	COG1505	serine-type exopeptidase activity
Tpau_3681	COG2326	polyphosphate kinase activity
Tpau_3684	COG1535	isochorismatase
Tpau_3684	COG3433	isochorismatase activity
Tpau_3685	COG1021	2,3-dihydroxybenzoate-AMP ligase
Tpau_3686	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3687	COG2375	cellular response to nickel ion
Tpau_3688	COG1132	(ABC) transporter
Tpau_3689	COG1132	(ABC) transporter
Tpau_3691	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Tpau_3692	COG1535	isochorismatase
Tpau_3692	COG3433	isochorismatase activity
Tpau_3693	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Tpau_3696	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tpau_3697	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_3701	COG0326	Molecular chaperone. Has ATPase activity
Tpau_3706	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tpau_3708	COG2261	transglycosylase associated protein
Tpau_3709	COG0688	phosphatidylethanolamine metabolic process
Tpau_3711	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tpau_3714	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Tpau_3714	COG2111	Na H antiporter
Tpau_3719	COG1320	monovalent cation:proton antiporter activity
Tpau_3720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Tpau_3725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Tpau_3726	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_3732	COG0456	acetyltransferase
Tpau_3735	COG4555	ABC transporter
Tpau_3737	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Tpau_3739	COG0351	phosphomethylpyrimidine kinase
Tpau_3743	COG2197	response regulator
Tpau_3744	COG0477	Major facilitator Superfamily
Tpau_3745	COG1403	HNH endonuclease
Tpau_3746	COG2022	thiamine diphosphate biosynthetic process
Tpau_3748	COG2022	thiamine diphosphate biosynthetic process
Tpau_3748	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Tpau_3749	COG0352	thiamine-phosphate diphosphorylase activity
Tpau_3750	COG1733	regulation of RNA biosynthetic process
Tpau_3754	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Tpau_3756	COG1120	ATPase activity
Tpau_3757	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_3758	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_3761	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Tpau_3763	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_3765	COG1132	(ABC) transporter
Tpau_3769	COG0657	acetylesterase activity
Tpau_3774	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Tpau_3775	COG1120	ATPase activity
Tpau_3776	COG2124	cytochrome p450
Tpau_3786	COG4941	Belongs to the sigma-70 factor family
Tpau_3787	COG1088	dTDP-glucose 4,6-dehydratase activity
Tpau_3788	COG1309	transcriptional regulator
Tpau_3789	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_3790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_3797	COG1960	acyl-CoA dehydrogenase activity
Tpau_3802	COG1414	Transcriptional regulator
Tpau_3805	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3806	COG1960	acyl-CoA dehydrogenase activity
Tpau_3807	COG1960	acyl-CoA dehydrogenase activity
Tpau_3808	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Tpau_3810	COG1793	dna ligase
Tpau_3812	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_3815	COG2070	2-Nitropropane dioxygenase
Tpau_3821	COG2124	cytochrome p450
Tpau_3822	COG0183	Belongs to the thiolase family
Tpau_3823	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tpau_3824	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3825	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3826	COG1250	3-hydroxyacyl-CoA dehydrogenase
Tpau_3826	COG1024	Enoyl-CoA hydratase
Tpau_3831	COG0745	RESPONSE REGULATOR receiver
Tpau_3832	COG0183	Belongs to the thiolase family
Tpau_3833	COG1309	transcriptional regulator
Tpau_3834	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_3835	COG1960	acyl-CoA dehydrogenase activity
Tpau_3836	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_3837	COG1024	Enoyl-CoA hydratase
Tpau_3838	COG1960	acyl-CoA dehydrogenase activity
Tpau_3840	COG1960	acyl-CoA dehydrogenase activity
Tpau_3842	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Tpau_3843	COG0346	lactoylglutathione lyase activity
Tpau_3844	COG2267	carboxylic ester hydrolase activity
Tpau_3845	COG1960	acyl-CoA dehydrogenase activity
Tpau_3846	COG1053	succinate dehydrogenase
Tpau_3848	COG1053	succinate dehydrogenase
Tpau_3849	COG4638	Rieske (2fe-2S)
Tpau_3855	COG1960	acyl-CoA dehydrogenase activity
Tpau_3856	COG2030	dehydratase
Tpau_3869	COG2508	Transcriptional regulator
Tpau_3870	COG2072	flavoprotein involved in K transport
Tpau_3874	COG0470	DNA polymerase III
Tpau_3876	COG1754	DNA topoisomerase type I activity
Tpau_3876	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Tpau_3879	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_3880	COG1278	Cold shock
Tpau_3881	COG1205	dead DEAH box helicase
Tpau_3881	COG1111	helicase
Tpau_3904	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Tpau_3913	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tpau_3914	COG0601	transmembrane transport
Tpau_3915	COG4166	transmembrane transport
Tpau_3916	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Tpau_3919	COG1131	(ABC) transporter
Tpau_3923	COG0477	Major facilitator Superfamily
Tpau_3924	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Tpau_3926	COG2267	carboxylic ester hydrolase activity
Tpau_3928	COG0494	nUDIX hydrolase
Tpau_3933	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tpau_3941	COG1024	Enoyl-CoA hydratase
Tpau_3943	COG1309	transcriptional regulator
Tpau_3944	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Tpau_3945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Tpau_3949	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Tpau_3950	COG3959	Transketolase, thiamine diphosphate binding domain
Tpau_3952	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_3959	COG1408	metallophosphoesterase
Tpau_3960	COG1610	YqeY-like protein
Tpau_3962	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Tpau_3963	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Tpau_3964	COG1764	response to oxidative stress
Tpau_3969	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_3971	COG0583	DNA-binding transcription factor activity
Tpau_3973	COG0768	penicillin binding
Tpau_3975	COG0135	phosphoribosylanthranilate isomerase activity
Tpau_3978	COG1528	Iron-storage protein
Tpau_3979	COG1309	transcriptional regulator
Tpau_3985	COG3251	PFAM MbtH domain protein
Tpau_3988	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Tpau_3989	COG0697	spore germination
Tpau_3990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Tpau_3991	COG1017	nitric oxide dioxygenase activity
Tpau_3991	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Tpau_3998	COG0477	Major facilitator Superfamily
Tpau_4000	COG0697	spore germination
Tpau_4002	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Tpau_4004	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Tpau_4010	COG0860	N-Acetylmuramoyl-L-alanine amidase
Tpau_4011	COG0564	pseudouridine synthase activity
Tpau_4014	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tpau_4018	COG1785	Belongs to the alkaline phosphatase family
Tpau_4021	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Tpau_4026	COG0596	Alpha beta hydrolase
Tpau_4032	COG0640	Transcriptional regulator
Tpau_4035	COG1228	amidohydrolase
Tpau_4036	COG0477	Major facilitator Superfamily
Tpau_4037	COG1522	sequence-specific DNA binding
Tpau_4039	COG1793	dna ligase
Tpau_4040	COG2318	DinB family
Tpau_4042	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Tpau_4044	COG2409	Drug exporters of the RND superfamily
Tpau_4050	COG0287	Prephenate dehydrogenase
Tpau_4055	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_4071	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Tpau_4075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Tpau_4079	COG4977	sequence-specific DNA binding
Tpau_4088	COG2826	transposase and inactivated derivatives, IS30 family
Tpau_4102	COG1216	Glycosyl transferase, family 2
Tpau_4103	COG0318	PFAM AMP-dependent synthetase and ligase
Tpau_4108	COG1476	TRANSCRIPTIONal
Tpau_4110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Tpau_4111	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_4112	COG0006	proline dipeptidase activity
Tpau_4113	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Tpau_4114	COG1473	amidohydrolase
Tpau_4118	COG1309	transcriptional regulator
Tpau_4119	COG0277	FAD linked oxidase domain protein
Tpau_4120	COG1028	Short-chain dehydrogenase reductase Sdr
Tpau_4122	COG4221	oxidoreductase activity
Tpau_4123	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tpau_4130	COG1122	ATPase activity
Tpau_4131	COG1268	BioY protein
Tpau_4133	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Tpau_4142	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Tpau_4150	COG1174	glycine betaine transport
Tpau_4155	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Tpau_4161	COG0300	oxidoreductase activity
Tpau_4166	COG0359	binds to the 23S rRNA
Tpau_4167	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Tpau_4169	COG0360	Binds together with S18 to 16S ribosomal RNA
Tpau_4171	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tpau_4182	COG0183	Belongs to the thiolase family
Tpau_4183	COG1250	3-hydroxyacyl-CoA dehydrogenase
Tpau_4183	COG1024	Enoyl-CoA hydratase
Tpau_4185	COG1024	Enoyl-CoA hydratase
Tpau_4192	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Tpau_4195	COG1260	myo-inositol-1-phosphate synthase
Tpau_4197	COG1297	OPT oligopeptide transporter protein
Tpau_4198	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Tpau_4203	COG1846	Transcriptional regulator
Tpau_4204	COG2814	Major facilitator Superfamily
Tpau_4205	COG4221	oxidoreductase activity
Tpau_4206	COG1940	carbohydrate kinase activity
Tpau_4206	COG1846	Transcriptional regulator
Tpau_4207	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Tpau_4209	COG0800	Aldolase
Tpau_4210	COG4214	carbohydrate transport
Tpau_4212	COG4213	ABC transporter substrate-binding protein
Tpau_4214	COG0495	leucyl-tRNA aminoacylation
Tpau_4219	COG1678	Uncharacterized ACR, COG1678
Tpau_4223	COG0617	tRNA 3'-terminal CCA addition
Tpau_4228	COG0519	Catalyzes the synthesis of GMP from XMP
Tpau_4229	COG1012	belongs to the aldehyde dehydrogenase family
Tpau_4230	COG1595	DNA-templated transcription, initiation
Tpau_4234	COG3409	Peptidoglycan-binding domain 1 protein
Tpau_4234	COG0860	N-Acetylmuramoyl-L-alanine amidase
Tpau_4237	COG1192	Involved in chromosome partitioning
Tpau_4238	COG0357	Ribosomal RNA small subunit methyltransferase G
Tpau_4241	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Tpau_4242	COG0594	ribonuclease P activity
Tpau_4253	COG0701	Predicted permease
Tpau_4256	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Tpau_4268	COG3328	transposase activity
Tpau_4284	COG3328	transposase activity
Tpau_4287	COG3328	transposase activity
Tpau_4290	COG0019	diaminopimelate decarboxylase activity
Tpau_4292	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Tpau_4295	COG1192	Involved in chromosome partitioning
Tpau_4300	COG3654	unkown
Tpau_4306	COG0659	secondary active sulfate transmembrane transporter activity
Tpau_4320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Tpau_4322	COG3321	synthase
Tpau_4325	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Tpau_4326	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Tpau_4326	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Tpau_4330	COG1169	isochorismate synthase
Tpau_4331	COG1021	2,3-dihydroxybenzoate-AMP ligase
Tpau_4335	COG3591	Belongs to the peptidase S1B family