locus-tag	class	description
TPB0596_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TPB0596_00030	COG0592	DNA-directed DNA polymerase activity
TPB0596_00040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TPB0596_00050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TPB0596_00060	COG1819	glycosyl
TPB0596_00070	COG0477	Major facilitator Superfamily
TPB0596_00100	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
TPB0596_00120	COG0187	DNA topoisomerase II activity
TPB0596_00130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TPB0596_00150	COG1253	flavin adenine dinucleotide binding
TPB0596_00170	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
TPB0596_00190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TPB0596_00320	COG2815	serine threonine protein kinase
TPB0596_00320	COG0515	serine threonine protein kinase
TPB0596_00330	COG0515	serine threonine protein kinase
TPB0596_00340	COG0768	penicillin binding
TPB0596_00370	COG1716	ATPase activity
TPB0596_00380	COG1716	ATPase activity
TPB0596_00750	COG2963	transposase activity
TPB0596_00810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TPB0596_00880	COG1120	ATPase activity
TPB0596_00930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TPB0596_00940	COG2079	MmgE PrpD family protein
TPB0596_00950	COG3800	Transcriptional regulator
TPB0596_00950	COG1396	sequence-specific DNA binding
TPB0596_01050	COG0415	Belongs to the DNA photolyase family
TPB0596_01140	COG0438	transferase activity, transferring glycosyl groups
TPB0596_01200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TPB0596_01240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TPB0596_01260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TPB0596_01380	COG2957	Belongs to the agmatine deiminase family
TPB0596_01400	COG2015	COG2015, Alkyl sulfatase and related hydrolases
TPB0596_01460	COG1073	alpha beta
TPB0596_01500	COG3336	cytochrome c oxidase
TPB0596_01550	COG0657	acetylesterase activity
TPB0596_01590	COG0778	Nitroreductase
TPB0596_01600	COG1376	ErfK ybiS ycfS ynhG family protein
TPB0596_01640	COG0745	RESPONSE REGULATOR receiver
TPB0596_01650	COG2205	protein histidine kinase activity
TPB0596_01680	COG0745	RESPONSE REGULATOR receiver
TPB0596_01690	COG2205	protein histidine kinase activity
TPB0596_01740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TPB0596_01750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TPB0596_01760	COG3559	Exporter of polyketide antibiotics
TPB0596_01770	COG1131	(ABC) transporter
TPB0596_01820	COG0667	Aldo Keto reductase
TPB0596_01840	COG0067	glutamate synthase
TPB0596_01840	COG0069	glutamate synthase activity
TPB0596_01840	COG0070	glutamate synthase
TPB0596_01890	COG2501	S4 domain
TPB0596_01930	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_02030	COG2119	membrane
TPB0596_02150	COG1316	TRANSCRIPTIONal
TPB0596_02170	COG2252	PERMEase
TPB0596_02280	COG0813	purine-nucleoside phosphorylase activity
TPB0596_02310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TPB0596_02330	COG2146	nitrite reductase [NAD(P)H] activity
TPB0596_02330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TPB0596_02350	COG0561	phosphatase activity
TPB0596_02360	COG2385	sporulation resulting in formation of a cellular spore
TPB0596_02380	COG1216	Glycosyl transferase, family 2
TPB0596_02390	COG0671	phosphoesterase, PA-phosphatase related
TPB0596_02400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TPB0596_02410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TPB0596_02440	COG5001	Diguanylate cyclase
TPB0596_02440	COG5002	protein histidine kinase activity
TPB0596_02480	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
TPB0596_02490	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
TPB0596_02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_02530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TPB0596_02530	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TPB0596_02530	COG3321	synthase
TPB0596_02540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TPB0596_02550	COG0277	FAD linked oxidase domain protein
TPB0596_02560	COG1956	GAF domain-containing protein
TPB0596_02620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TPB0596_02630	COG1349	DNA-binding transcription factor activity
TPB0596_02650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TPB0596_02650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TPB0596_02650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TPB0596_02680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TPB0596_02700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TPB0596_02710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
TPB0596_02780	COG3191	aminopeptidase activity
TPB0596_02800	COG1846	Transcriptional regulator
TPB0596_02870	COG0477	Major facilitator Superfamily
TPB0596_02890	COG1396	sequence-specific DNA binding
TPB0596_02900	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TPB0596_02910	COG1760	l-serine dehydratase
TPB0596_02930	COG1051	belongs to the nudix hydrolase family
TPB0596_02940	COG3214	Protein conserved in bacteria
TPB0596_02960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TPB0596_02970	COG3559	Exporter of polyketide antibiotics
TPB0596_02980	COG1131	(ABC) transporter
TPB0596_02990	COG1309	transcriptional regulator
TPB0596_03010	COG0488	(ABC) transporter
TPB0596_03110	COG1674	ftsk spoiiie
TPB0596_03190	COG1404	Belongs to the peptidase S8 family
TPB0596_03270	COG1309	transcriptional regulator
TPB0596_03280	COG0183	Belongs to the thiolase family
TPB0596_03290	COG1024	Enoyl-CoA hydratase
TPB0596_03290	COG1250	3-hydroxyacyl-CoA dehydrogenase
TPB0596_03430	COG1309	transcriptional regulator
TPB0596_03520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TPB0596_03520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TPB0596_03530	COG2409	Drug exporters of the RND superfamily
TPB0596_03550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TPB0596_03630	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TPB0596_03660	COG0464	growth
TPB0596_03680	COG1136	(ABC) transporter
TPB0596_03680	COG0577	efflux transmembrane transporter activity
TPB0596_03700	COG1252	NADH dehydrogenase
TPB0596_03770	COG0492	ferredoxin-NADP+ reductase activity
TPB0596_03880	COG4981	capsule polysaccharide biosynthetic process
TPB0596_03920	COG1472	Belongs to the glycosyl hydrolase 3 family
TPB0596_03930	COG1309	transcriptional regulator
TPB0596_03950	COG2030	dehydratase
TPB0596_03960	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_03970	COG0183	Belongs to the thiolase family
TPB0596_03980	COG1832	CoA-binding protein
TPB0596_04030	COG1960	acyl-CoA dehydrogenase activity
TPB0596_04060	COG1309	transcriptional regulator
TPB0596_04070	COG0300	oxidoreductase activity
TPB0596_04100	COG0477	Major facilitator Superfamily
TPB0596_04140	COG1115	amino acid carrier protein
TPB0596_04160	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_04170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TPB0596_04180	COG2066	Belongs to the glutaminase family
TPB0596_04180	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
TPB0596_04190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TPB0596_04210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TPB0596_04380	COG3655	Transcriptional regulator
TPB0596_04600	COG2963	transposase activity
TPB0596_04770	COG0582	viral genome integration into host DNA
TPB0596_04850	COG2181	nitrate reductase activity
TPB0596_04850	COG0247	lactate metabolic process
TPB0596_04940	COG0708	Exodeoxyribonuclease III
TPB0596_05090	COG0443	Heat shock 70 kDa protein
TPB0596_05100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TPB0596_05110	COG0484	heat shock protein binding
TPB0596_05120	COG0789	Transcriptional regulator
TPB0596_05160	COG0154	amidase activity
TPB0596_05190	COG2267	carboxylic ester hydrolase activity
TPB0596_05230	COG2149	membrane
TPB0596_05270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TPB0596_05330	COG3609	addiction module antidote protein, CC2985 family
TPB0596_05350	COG0488	(ABC) transporter
TPB0596_05360	COG0586	Pfam SNARE associated Golgi protein
TPB0596_05370	COG0586	Pfam SNARE associated Golgi protein
TPB0596_05430	COG4129	membrane
TPB0596_05450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TPB0596_05480	COG2814	Major facilitator Superfamily
TPB0596_05490	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
TPB0596_05510	COG1695	Transcriptional regulator
TPB0596_05540	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_05610	COG3142	Participates in the control of copper homeostasis
TPB0596_05640	COG1690	Belongs to the RtcB family
TPB0596_05700	COG0442	prolyl-tRNA aminoacylation
TPB0596_05720	COG0477	Major facilitator Superfamily
TPB0596_05740	COG2027	D-alanyl-D-alanine carboxypeptidase
TPB0596_05760	COG0037	tRNA processing
TPB0596_05770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TPB0596_05800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TPB0596_05820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TPB0596_05880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TPB0596_05890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TPB0596_05900	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TPB0596_05920	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TPB0596_05960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TPB0596_05990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TPB0596_06040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TPB0596_06050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TPB0596_06060	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_06080	COG1194	a g-specific adenine glycosylase
TPB0596_06090	COG0288	reversible hydration of carbon dioxide
TPB0596_06120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TPB0596_06150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TPB0596_06180	COG0215	cysteine-tRNA ligase activity
TPB0596_06190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TPB0596_06210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TPB0596_06220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TPB0596_06230	COG1116	anion transmembrane transporter activity
TPB0596_06270	COG1741	Belongs to the pirin family
TPB0596_06280	COG2267	carboxylic ester hydrolase activity
TPB0596_06290	COG0438	transferase activity, transferring glycosyl groups
TPB0596_06370	COG1309	transcriptional regulator
TPB0596_06390	COG0477	Major facilitator Superfamily
TPB0596_06410	COG0640	Transcriptional regulator
TPB0596_06440	COG0667	Aldo Keto reductase
TPB0596_06460	COG2318	DinB family
TPB0596_06480	COG1119	ATPase activity
TPB0596_06490	COG4106	trans-aconitate 2-methyltransferase activity
TPB0596_06500	COG0583	DNA-binding transcription factor activity
TPB0596_06510	COG2814	Major facilitator Superfamily
TPB0596_06520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_06550	COG1136	(ABC) transporter
TPB0596_06560	COG2197	response regulator
TPB0596_06580	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
TPB0596_06600	COG0588	phosphoglycerate mutase activity
TPB0596_06620	COG5002	protein histidine kinase activity
TPB0596_06630	COG0745	RESPONSE REGULATOR receiver
TPB0596_06700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TPB0596_06770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TPB0596_06780	COG0181	hydroxymethylbilane synthase activity
TPB0596_06790	COG1648	precorrin-2 dehydrogenase activity
TPB0596_06790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TPB0596_06850	COG2608	mercury ion transmembrane transporter activity
TPB0596_06860	COG2954	triphosphatase activity
TPB0596_06870	COG2409	Drug exporters of the RND superfamily
TPB0596_06920	COG2272	Belongs to the type-B carboxylesterase lipase family
TPB0596_06930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TPB0596_06940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TPB0596_06950	COG0406	alpha-ribazole phosphatase activity
TPB0596_06960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TPB0596_06970	COG0785	Cytochrome C biogenesis protein
TPB0596_06990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TPB0596_07020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TPB0596_07050	COG1960	acyl-CoA dehydrogenase activity
TPB0596_07120	COG3629	intracellular signal transduction
TPB0596_07240	COG4948	Mandelate Racemase Muconate Lactonizing
TPB0596_07290	COG0154	amidase activity
TPB0596_07310	COG2409	Drug exporters of the RND superfamily
TPB0596_07330	COG1937	Protein conserved in bacteria
TPB0596_07340	COG3268	Saccharopine dehydrogenase
TPB0596_07350	COG3180	Ammonia monooxygenase
TPB0596_07370	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TPB0596_07390	COG0438	transferase activity, transferring glycosyl groups
TPB0596_07400	COG2226	methyltransferase
TPB0596_07410	COG0142	geranyltranstransferase activity
TPB0596_07420	COG0501	Belongs to the peptidase M48B family
TPB0596_07430	COG1666	GTP binding
TPB0596_07440	COG2030	dehydratase
TPB0596_07450	COG2030	dehydratase
TPB0596_07480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TPB0596_07490	COG0081	regulation of translation
TPB0596_07550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TPB0596_07580	COG0085	RNA polymerase activity
TPB0596_07650	COG2814	Major facilitator Superfamily
TPB0596_07660	COG0179	Fumarylacetoacetate (FAA) hydrolase
TPB0596_07670	COG4948	Mandelate Racemase Muconate Lactonizing
TPB0596_07680	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_07700	COG2186	Transcriptional regulator
TPB0596_07710	COG3304	Inner membrane component domain
TPB0596_07770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TPB0596_07800	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_07820	COG2376	Dihydroxyacetone kinase
TPB0596_07910	COG0640	Transcriptional regulator
TPB0596_07920	COG0765	amino acid transport
TPB0596_07930	COG1126	abc transporter atp-binding protein
TPB0596_07950	COG0384	phenazine biosynthesis protein PhzF
TPB0596_07960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TPB0596_07970	COG1263	PTS System
TPB0596_07980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TPB0596_08030	COG2311	Membrane
TPB0596_08040	COG2188	Transcriptional regulator
TPB0596_08060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_08200	COG1061	Type III restriction enzyme res subunit
TPB0596_08420	COG2814	Major facilitator Superfamily
TPB0596_08510	COG2814	Major facilitator Superfamily
TPB0596_08570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TPB0596_08590	COG0259	pyridoxamine-phosphate oxidase activity
TPB0596_08600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TPB0596_08670	COG0545	Peptidyl-prolyl cis-trans isomerase
TPB0596_08730	COG0656	L-ascorbic acid biosynthetic process
TPB0596_08790	COG1408	metallophosphoesterase
TPB0596_08800	COG0328	RNA-DNA hybrid ribonuclease activity
TPB0596_08880	COG1218	3'(2'),5'-bisphosphate nucleotidase
TPB0596_08890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TPB0596_08950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_08960	COG2364	Membrane
TPB0596_08990	COG2084	Dehydrogenase
TPB0596_09110	COG0739	heme binding
TPB0596_09120	COG1116	anion transmembrane transporter activity
TPB0596_09130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TPB0596_09140	COG1285	pathogenesis
TPB0596_09160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TPB0596_09180	COG1960	acyl-CoA dehydrogenase activity
TPB0596_09210	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_09220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TPB0596_09330	COG2814	Major facilitator Superfamily
TPB0596_09400	COG0640	Transcriptional regulator
TPB0596_09430	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TPB0596_09480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TPB0596_09490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TPB0596_09510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TPB0596_09530	COG0254	rRNA binding
TPB0596_09550	COG2860	membrane
TPB0596_09590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TPB0596_09600	COG0521	Mo-molybdopterin cofactor biosynthetic process
TPB0596_09670	COG1970	mechanosensitive ion channel activity
TPB0596_09750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TPB0596_09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TPB0596_09780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TPB0596_09800	COG4974	Belongs to the 'phage' integrase family
TPB0596_10160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TPB0596_10280	COG2801	Transposase and inactivated derivatives
TPB0596_10350	COG1733	regulation of RNA biosynthetic process
TPB0596_10400	COG5473	translation initiation factor activity
TPB0596_10410	COG2267	carboxylic ester hydrolase activity
TPB0596_10430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
TPB0596_10460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TPB0596_10510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
TPB0596_10520	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
TPB0596_10530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
TPB0596_10540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
TPB0596_10560	COG0477	Major facilitator Superfamily
TPB0596_10650	COG0084	hydrolase, TatD family'
TPB0596_10660	COG3583	domain protein
TPB0596_10670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TPB0596_10680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TPB0596_10710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TPB0596_10720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TPB0596_10730	COG0488	(ABC) transporter
TPB0596_10790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TPB0596_10810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TPB0596_10820	COG0546	phosphoglycolate phosphatase activity
TPB0596_10880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TPB0596_10910	COG2154	pterin-4-alpha-carbinolamine dehydratase
TPB0596_10970	COG0456	acetyltransferase
TPB0596_10980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TPB0596_11100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TPB0596_11110	COG0459	protein refolding
TPB0596_11180	COG0516	GMP reductase activity
TPB0596_11220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TPB0596_11220	COG0519	Catalyzes the synthesis of GMP from XMP
TPB0596_11230	COG0702	epimerase
TPB0596_11280	COG2197	response regulator
TPB0596_11290	COG0515	serine threonine protein kinase
TPB0596_11290	COG2815	serine threonine protein kinase
TPB0596_11340	COG0833	amino acid
TPB0596_11430	COG0587	DNA-directed DNA polymerase activity
TPB0596_11470	COG1872	DUF167
TPB0596_11500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TPB0596_11520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TPB0596_11560	COG2814	Major facilitator Superfamily
TPB0596_11590	COG0708	Exodeoxyribonuclease III
TPB0596_11600	COG0180	Tryptophanyl-tRNA synthetase
TPB0596_11610	COG1295	ribonuclease BN
TPB0596_11630	COG1686	Belongs to the peptidase S11 family
TPB0596_11730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TPB0596_11760	COG2009	succinate dehydrogenase
TPB0596_11790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TPB0596_11810	COG2197	response regulator
TPB0596_12620	COG3179	chitinase
TPB0596_12720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TPB0596_12760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
TPB0596_12760	COG1473	amidohydrolase
TPB0596_12820	COG1595	DNA-templated transcription, initiation
TPB0596_12900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_12910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TPB0596_12940	COG2197	response regulator
TPB0596_12960	COG0477	Major facilitator Superfamily
TPB0596_12980	COG3360	Dodecin
TPB0596_13010	COG1201	RNA secondary structure unwinding
TPB0596_13020	COG2272	Belongs to the type-B carboxylesterase lipase family
TPB0596_13040	COG0431	NADPH-dependent FMN reductase
TPB0596_13060	COG1396	sequence-specific DNA binding
TPB0596_13090	COG4770	biotin carboxylase activity
TPB0596_13160	COG2755	lipolytic protein G-D-S-L family
TPB0596_13200	COG0424	maF-like protein
TPB0596_13220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TPB0596_13250	COG0745	RESPONSE REGULATOR receiver
TPB0596_13270	COG2205	protein histidine kinase activity
TPB0596_13290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TPB0596_13320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPB0596_13360	COG1316	TRANSCRIPTIONal
TPB0596_13390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TPB0596_13400	COG2755	lipolytic protein G-D-S-L family
TPB0596_13410	COG4122	O-methyltransferase activity
TPB0596_13420	COG1595	DNA-templated transcription, initiation
TPB0596_13430	COG5662	AntiSigma factor
TPB0596_13440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TPB0596_13450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TPB0596_13500	COG0745	RESPONSE REGULATOR receiver
TPB0596_13510	COG5002	protein histidine kinase activity
TPB0596_13520	COG5401	PFAM Sporulation and spore germination
TPB0596_13540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TPB0596_13550	COG0653	protein targeting
TPB0596_13680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TPB0596_13700	COG1162	GTPase activity
TPB0596_13710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TPB0596_13740	COG2135	peptidase activity
TPB0596_13750	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_13770	COG4221	oxidoreductase activity
TPB0596_13780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TPB0596_13790	COG1595	DNA-templated transcription, initiation
TPB0596_13850	COG0406	alpha-ribazole phosphatase activity
TPB0596_13900	COG1090	epimerase
TPB0596_13930	COG0513	Belongs to the DEAD box helicase family
TPB0596_13950	COG1309	transcriptional regulator
TPB0596_13960	COG0596	Alpha beta hydrolase
TPB0596_14050	COG0596	Alpha beta hydrolase
TPB0596_14090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TPB0596_14190	COG1960	acyl-CoA dehydrogenase activity
TPB0596_14240	COG3480	Lon protease (S16) C-terminal proteolytic domain
TPB0596_14260	COG1615	UPF0182 protein
TPB0596_14270	COG0110	maltose O-acetyltransferase activity
TPB0596_14290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_14310	COG0730	response to heat
TPB0596_14320	COG0456	acetyltransferase
TPB0596_14330	COG2814	Major facilitator Superfamily
TPB0596_14340	COG1388	LysM domain
TPB0596_14350	COG2409	Drug exporters of the RND superfamily
TPB0596_14360	COG2197	response regulator
TPB0596_14380	COG1960	acyl-CoA dehydrogenase activity
TPB0596_14390	COG1960	acyl-CoA dehydrogenase activity
TPB0596_14400	COG0483	inositol monophosphate 1-phosphatase activity
TPB0596_14420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TPB0596_14430	COG0668	transmembrane transport
TPB0596_14450	COG2884	Cell division ATP-binding protein ftsE
TPB0596_14460	COG2177	Part of the ABC transporter FtsEX involved in
TPB0596_14470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TPB0596_14540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
TPB0596_14570	COG1414	Transcriptional regulator
TPB0596_14600	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
TPB0596_14610	COG0800	Aldolase
TPB0596_14620	COG2610	gluconate transmembrane transporter activity
TPB0596_14660	COG3634	alkyl hydroperoxide reductase activity
TPB0596_14730	COG0640	Transcriptional regulator
TPB0596_14750	COG2084	Dehydrogenase
TPB0596_14770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TPB0596_14780	COG2267	carboxylic ester hydrolase activity
TPB0596_14810	COG1116	anion transmembrane transporter activity
TPB0596_14820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TPB0596_14840	COG1054	Belongs to the UPF0176 family
TPB0596_14920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TPB0596_15020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_15030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_15040	COG0655	NAD(P)H dehydrogenase (quinone) activity
TPB0596_15050	COG0783	Belongs to the Dps family
TPB0596_15060	COG2264	protein methyltransferase activity
TPB0596_15100	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_15170	COG0753	catalase activity
TPB0596_15200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TPB0596_15290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TPB0596_15310	COG3813	Protein conserved in bacteria
TPB0596_15380	COG0560	Phosphoserine phosphatase
TPB0596_15380	COG3830	Belongs to the UPF0237 family
TPB0596_15390	COG1523	belongs to the glycosyl hydrolase 13 family
TPB0596_15400	COG1119	ATPase activity
TPB0596_15430	COG2226	methyltransferase
TPB0596_15450	COG0436	Aminotransferase
TPB0596_15480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TPB0596_15490	COG0024	Methionine aminopeptidase
TPB0596_15510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TPB0596_15520	COG0110	maltose O-acetyltransferase activity
TPB0596_15570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TPB0596_15590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TPB0596_15610	COG2197	response regulator
TPB0596_15620	COG4585	Histidine kinase
TPB0596_15630	COG2132	Multicopper oxidase
TPB0596_15760	COG0482	sulfurtransferase activity
TPB0596_15830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TPB0596_15890	COG0154	amidase activity
TPB0596_15930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TPB0596_15940	COG1959	2 iron, 2 sulfur cluster binding
TPB0596_15970	COG4585	Histidine kinase
TPB0596_15980	COG2197	response regulator
TPB0596_15990	COG0205	6-phosphofructokinase activity
TPB0596_16010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TPB0596_16040	COG0129	dihydroxy-acid dehydratase activity
TPB0596_16080	COG0440	acetolactate synthase activity
TPB0596_16090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TPB0596_16170	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_16200	COG0473	3-isopropylmalate dehydrogenase activity
TPB0596_16210	COG2271	Major facilitator Superfamily
TPB0596_16220	COG0179	Fumarylacetoacetate (FAA) hydrolase
TPB0596_16240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TPB0596_16280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TPB0596_16310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TPB0596_16320	COG0066	3-isopropylmalate dehydratase activity
TPB0596_16350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TPB0596_16360	COG1920	GTP binding
TPB0596_16370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TPB0596_16420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TPB0596_16430	COG1461	Dihydroxyacetone kinase
TPB0596_16440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TPB0596_16450	COG1309	transcriptional regulator
TPB0596_16460	COG1024	Enoyl-CoA hydratase
TPB0596_16490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TPB0596_16500	COG1960	acyl-CoA dehydrogenase activity
TPB0596_16540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TPB0596_16590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TPB0596_16600	COG0799	negative regulation of ribosome biogenesis
TPB0596_16610	COG0406	alpha-ribazole phosphatase activity
TPB0596_16620	COG2755	lipolytic protein G-D-S-L family
TPB0596_16630	COG1307	EDD domain protein, DegV family
TPB0596_16640	COG1555	photosystem II stabilization
TPB0596_16640	COG1596	polysaccharide export
TPB0596_16680	COG0268	Binds directly to 16S ribosomal RNA
TPB0596_16710	COG1305	Transglutaminase-like
TPB0596_16750	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_16760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TPB0596_16790	COG0481	GTPase activity
TPB0596_16800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TPB0596_16810	COG0656	L-ascorbic acid biosynthetic process
TPB0596_16820	COG2814	Major facilitator Superfamily
TPB0596_16830	COG1846	Transcriptional regulator
TPB0596_16870	COG2070	2-Nitropropane dioxygenase
TPB0596_16890	COG0339	signal peptide processing
TPB0596_16920	COG3387	PFAM Glycoside hydrolase 15-related
TPB0596_16960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
TPB0596_16970	COG4208	sulfate ABC transporter
TPB0596_16980	COG3842	ATPase activity
TPB0596_16990	COG4552	Acetyltransferase involved in intracellular survival and related
TPB0596_17020	COG0175	sulfate reduction
TPB0596_17080	COG1420	regulation of RNA biosynthetic process
TPB0596_17090	COG0484	heat shock protein binding
TPB0596_17130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TPB0596_17170	COG1381	Involved in DNA repair and RecF pathway recombination
TPB0596_17180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TPB0596_17210	COG1764	response to oxidative stress
TPB0596_17220	COG1846	Transcriptional regulator
TPB0596_17230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TPB0596_17300	COG0423	glycine-tRNA ligase activity
TPB0596_17320	COG1278	Cold shock
TPB0596_17330	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TPB0596_17340	COG0358	DNA primase activity
TPB0596_17390	COG0488	(ABC) transporter
TPB0596_17520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TPB0596_17550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TPB0596_17600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TPB0596_17630	COG2409	Drug exporters of the RND superfamily
TPB0596_17740	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
TPB0596_17780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TPB0596_17790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TPB0596_17790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TPB0596_17820	COG0174	glutamine synthetase
TPB0596_17830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
TPB0596_17900	COG0174	glutamine synthetase
TPB0596_17930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TPB0596_17970	COG0321	lipoyl(octanoyl) transferase activity
TPB0596_18040	COG2233	PERMEase
TPB0596_18050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TPB0596_18060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TPB0596_18090	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TPB0596_18140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TPB0596_18170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TPB0596_18230	COG2010	Cytochrome c
TPB0596_18240	COG1845	cytochrome c oxidase, subunit III
TPB0596_18260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TPB0596_18270	COG0442	prolyl-tRNA aminoacylation
TPB0596_18340	COG0438	transferase activity, transferring glycosyl groups
TPB0596_18400	COG1940	carbohydrate kinase activity
TPB0596_18410	COG0765	amino acid transport
TPB0596_18450	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
TPB0596_18490	COG2357	RelA SpoT domain protein
TPB0596_18500	COG2815	serine threonine protein kinase
TPB0596_18500	COG0515	serine threonine protein kinase
TPB0596_18540	COG4604	ABC transporter, ATP-binding protein
TPB0596_18570	COG4607	ABC-type enterochelin transport system periplasmic component
TPB0596_18580	COG0142	geranyltranstransferase activity
TPB0596_18650	COG2001	Belongs to the MraZ family
TPB0596_18660	COG0275	rRNA processing
TPB0596_18680	COG0768	penicillin binding
TPB0596_18710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TPB0596_18720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TPB0596_18750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TPB0596_18760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TPB0596_18770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TPB0596_18790	COG1799	cell septum assembly
TPB0596_18830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TPB0596_18900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TPB0596_18910	COG0252	asparaginase activity
TPB0596_18940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TPB0596_18980	COG1090	epimerase
TPB0596_19050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TPB0596_19060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TPB0596_19110	COG0006	proline dipeptidase activity
TPB0596_19120	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TPB0596_19150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TPB0596_19190	COG0505	Belongs to the CarA family
TPB0596_19200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TPB0596_19210	COG0284	orotidine-5'-phosphate decarboxylase activity
TPB0596_19230	COG0475	glutathione-regulated potassium exporter activity
TPB0596_19260	COG1758	RNA polymerase activity
TPB0596_19280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TPB0596_19340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TPB0596_19360	COG0242	peptide deformylase activity
TPB0596_19370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TPB0596_19430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TPB0596_19430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TPB0596_19440	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TPB0596_19490	COG3104	oligopeptide transport
TPB0596_19570	COG0322	excinuclease ABC activity
TPB0596_19610	COG3842	ATPase activity
TPB0596_19630	COG0405	Gamma-glutamyltransferase
TPB0596_19660	COG1660	Displays ATPase and GTPase activities
TPB0596_19670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TPB0596_19680	COG1481	regulation of sporulation
TPB0596_19700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TPB0596_19710	COG0126	phosphoglycerate kinase activity
TPB0596_19730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TPB0596_19740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TPB0596_19750	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
TPB0596_19760	COG1960	acyl-CoA dehydrogenase activity
TPB0596_19870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TPB0596_19890	COG0109	protoheme IX farnesyltransferase activity
TPB0596_19910	COG1309	transcriptional regulator
TPB0596_19970	COG1131	(ABC) transporter
TPB0596_20020	COG0396	ATPase activity
TPB0596_20050	COG2151	metal-sulfur cluster biosynthetic enzyme
TPB0596_20140	COG1960	acyl-CoA dehydrogenase activity
TPB0596_20170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TPB0596_20220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TPB0596_20240	COG1946	Acyl-CoA thioesterase
TPB0596_20260	COG0457	Tetratricopeptide repeat
TPB0596_20260	COG0705	Rhomboid family
TPB0596_20310	COG3243	poly(R)-hydroxyalkanoic acid synthase
TPB0596_20360	COG1278	Cold shock
TPB0596_20490	COG2963	transposase activity
TPB0596_20500	COG1733	regulation of RNA biosynthetic process
TPB0596_20530	COG3634	alkyl hydroperoxide reductase activity
TPB0596_20540	COG0477	Major facilitator Superfamily
TPB0596_20560	COG2409	Drug exporters of the RND superfamily
TPB0596_20590	COG0596	Alpha beta hydrolase
TPB0596_20630	COG0583	DNA-binding transcription factor activity
TPB0596_20640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TPB0596_20660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TPB0596_20670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TPB0596_20680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
TPB0596_20910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TPB0596_20960	COG1024	Enoyl-CoA hydratase
TPB0596_21020	COG1285	pathogenesis
TPB0596_21060	COG0531	amino acid
TPB0596_21080	COG4303	Ethanolamine ammonia lyase large subunit
TPB0596_21140	COG0435	Glutathione S-transferase
TPB0596_21150	COG1902	pentaerythritol trinitrate reductase activity
TPB0596_21160	COG0789	Transcriptional regulator
TPB0596_21190	COG0596	Alpha beta hydrolase
TPB0596_21210	COG0477	Major facilitator Superfamily
TPB0596_21240	COG0789	Transcriptional regulator
TPB0596_21260	COG3422	double-strand break repair
TPB0596_21270	COG4260	virion core protein, lumpy skin disease virus
TPB0596_21380	COG2226	methyltransferase
TPB0596_21390	COG0539	negative regulation of cytoplasmic translation
TPB0596_21400	COG3842	ATPase activity
TPB0596_21410	COG0395	ABC-type sugar transport system, permease component
TPB0596_21420	COG1175	transmembrane transport
TPB0596_21450	COG1063	alcohol dehydrogenase
TPB0596_21460	COG0246	Mannitol dehydrogenase
TPB0596_21470	COG1070	Carbohydrate kinase
TPB0596_21500	COG0237	dephospho-CoA kinase activity
TPB0596_21500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TPB0596_21520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TPB0596_21580	COG3973	AAA domain
TPB0596_21600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPB0596_21620	COG0405	Gamma-glutamyltransferase
TPB0596_21670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TPB0596_21680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TPB0596_21710	COG2233	PERMEase
TPB0596_21730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TPB0596_21740	COG0072	phenylalanine-tRNA ligase activity
TPB0596_21740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TPB0596_21750	COG2072	flavoprotein involved in K transport
TPB0596_21800	COG1024	Enoyl-CoA hydratase
TPB0596_21830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TPB0596_21840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TPB0596_21860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TPB0596_21870	COG1438	arginine binding
TPB0596_21880	COG0137	argininosuccinate synthase activity
TPB0596_21890	COG0165	Argininosuccinate lyase
TPB0596_21920	COG1131	(ABC) transporter
TPB0596_21930	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_21980	COG2835	tetraacyldisaccharide 4'-kinase activity
TPB0596_22000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TPB0596_22020	COG0647	UMP catabolic process
TPB0596_22090	COG0504	CTP synthase activity
TPB0596_22100	COG0494	nUDIX hydrolase
TPB0596_22130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TPB0596_22140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TPB0596_22170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TPB0596_22180	COG1160	GTP binding
TPB0596_22240	COG2365	Tyrosine phosphatase family
TPB0596_22280	COG2249	NAD(P)H dehydrogenase (quinone) activity
TPB0596_22330	COG0596	Alpha beta hydrolase
TPB0596_22350	COG2234	aminopeptidase activity
TPB0596_22380	COG0509	glycine decarboxylation via glycine cleavage system
TPB0596_22390	COG1716	ATPase activity
TPB0596_22430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TPB0596_22430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TPB0596_22460	COG1309	transcriptional regulator
TPB0596_22470	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_22490	COG1403	HNH endonuclease
TPB0596_22590	COG0739	heme binding
TPB0596_22610	COG1120	ATPase activity
TPB0596_22620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPB0596_22650	COG1253	flavin adenine dinucleotide binding
TPB0596_22830	COG4762	Protein conserved in bacteria
TPB0596_22880	COG1074	ATP-dependent DNA helicase activity
TPB0596_22890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TPB0596_22910	COG1063	alcohol dehydrogenase
TPB0596_22980	COG2268	Band 7 protein
TPB0596_23140	COG2963	transposase activity
TPB0596_23220	COG0297	glycogen (starch) synthase activity
TPB0596_23230	COG0438	transferase activity, transferring glycosyl groups
TPB0596_23240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TPB0596_23270	COG0736	holo-[acyl-carrier-protein] synthase activity
TPB0596_23300	COG4106	trans-aconitate 2-methyltransferase activity
TPB0596_23370	COG2354	Protein conserved in bacteria
TPB0596_23420	COG1280	lysine exporter protein (LysE YggA)
TPB0596_23430	COG1250	3-hydroxyacyl-CoA dehydrogenase
TPB0596_23460	COG0477	Major facilitator Superfamily
TPB0596_23470	COG1984	allophanate hydrolase subunit 2
TPB0596_23530	COG2072	flavoprotein involved in K transport
TPB0596_23580	COG0798	PFAM Bile acid sodium symporter
TPB0596_23590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TPB0596_23640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TPB0596_23660	COG2807	transmembrane transport
TPB0596_23670	COG2186	Transcriptional regulator
TPB0596_23710	COG1454	alcohol dehydrogenase
TPB0596_23760	COG2072	flavoprotein involved in K transport
TPB0596_23770	COG1376	ErfK ybiS ycfS ynhG family protein
TPB0596_23820	COG0463	Glycosyl transferase, family 2
TPB0596_23840	COG1228	amidohydrolase
TPB0596_23900	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TPB0596_23940	COG3467	pyridoxamine 5'-phosphate
TPB0596_24030	COG0300	oxidoreductase activity
TPB0596_24050	COG0477	Major facilitator Superfamily
TPB0596_24110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TPB0596_24120	COG2378	regulation of single-species biofilm formation
TPB0596_24160	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_24170	COG0733	neurotransmitter:sodium symporter activity
TPB0596_24190	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TPB0596_24200	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TPB0596_24280	COG1716	ATPase activity
TPB0596_24280	COG1131	(ABC) transporter
TPB0596_24280	COG0842	Transport permease protein
TPB0596_24290	COG1222	aaa ATPase
TPB0596_24330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TPB0596_24340	COG0140	phosphoribosyl-ATP diphosphatase activity
TPB0596_24370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TPB0596_24390	COG5504	Zn-dependent protease
TPB0596_24410	COG1410	methionine synthase
TPB0596_24410	COG0646	methionine synthase
TPB0596_24440	COG0215	cysteine-tRNA ligase activity
TPB0596_24460	COG3220	belongs to the UPF0276 family
TPB0596_24510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TPB0596_24520	COG0583	DNA-binding transcription factor activity
TPB0596_24530	COG1968	undecaprenyl-diphosphatase activity
TPB0596_24560	COG0167	dihydroorotate dehydrogenase activity
TPB0596_24580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TPB0596_24740	COG0531	amino acid
TPB0596_24760	COG5001	Diguanylate cyclase
TPB0596_24780	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TPB0596_24790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TPB0596_24810	COG0028	Belongs to the TPP enzyme family
TPB0596_24830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
TPB0596_24880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TPB0596_24890	COG2186	Transcriptional regulator
TPB0596_25090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TPB0596_25100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TPB0596_25140	COG0714	Associated with various cellular activities
TPB0596_25150	COG0791	NLP P60 protein
TPB0596_25150	COG3883	PFAM NLP P60 protein
TPB0596_25170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TPB0596_25180	COG1309	transcriptional regulator
TPB0596_25220	COG0584	glycerophosphoryl diester phosphodiesterase
TPB0596_25280	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_25290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TPB0596_25300	COG1309	transcriptional regulator
TPB0596_25310	COG1819	glycosyl
TPB0596_25350	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_25360	COG0488	(ABC) transporter
TPB0596_25380	COG0159	tryptophan synthase activity
TPB0596_25410	COG0765	amino acid transport
TPB0596_25420	COG1126	abc transporter atp-binding protein
TPB0596_25440	COG2188	Transcriptional regulator
TPB0596_25450	COG2814	Major facilitator Superfamily
TPB0596_25460	COG2971	BadF BadG BcrA BcrD
TPB0596_25470	COG0134	indole-3-glycerol-phosphate synthase activity
TPB0596_25490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TPB0596_25510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TPB0596_25520	COG0107	imidazoleglycerol-phosphate synthase activity
TPB0596_25530	COG0483	inositol monophosphate 1-phosphatase activity
TPB0596_25540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TPB0596_25560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TPB0596_25610	COG1414	Transcriptional regulator
TPB0596_25620	COG2252	PERMEase
TPB0596_25640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TPB0596_25660	COG0402	S-adenosylhomocysteine deaminase activity
TPB0596_25680	COG3257	ureidoglycine aminohydrolase activity
TPB0596_25700	COG1953	Uracil, thiamine, allantoin
TPB0596_25710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TPB0596_25740	COG0131	Imidazoleglycerol-phosphate dehydratase
TPB0596_25750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TPB0596_25760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TPB0596_25770	COG1535	isochorismatase
TPB0596_25770	COG3433	isochorismatase activity
TPB0596_25850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TPB0596_25880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_25900	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TPB0596_25930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TPB0596_25950	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TPB0596_25960	COG0156	8-amino-7-oxononanoate synthase activity
TPB0596_25970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TPB0596_26010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_26020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_26070	COG4585	Histidine kinase
TPB0596_26080	COG2197	response regulator
TPB0596_26100	COG1126	abc transporter atp-binding protein
TPB0596_26130	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_26140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_26150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_26160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_26170	COG1846	Transcriptional regulator
TPB0596_26200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TPB0596_26210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TPB0596_26230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TPB0596_26290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPB0596_26300	COG0444	Belongs to the ABC transporter superfamily
TPB0596_26340	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TPB0596_26380	COG0277	FAD linked oxidase domain protein
TPB0596_26410	COG0523	cobalamin synthesis protein
TPB0596_26450	COG0124	histidyl-tRNA synthetase
TPB0596_26480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TPB0596_26500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TPB0596_26520	COG1862	Preprotein translocase
TPB0596_26530	COG0514	ATP-dependent DNA helicase (RecQ)
TPB0596_26560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TPB0596_26570	COG2255	four-way junction helicase activity
TPB0596_26590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TPB0596_26610	COG0217	transcriptional regulatory protein
TPB0596_26630	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TPB0596_26640	COG1946	Acyl-CoA thioesterase
TPB0596_26670	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TPB0596_26710	COG0438	transferase activity, transferring glycosyl groups
TPB0596_26720	COG1560	Kdo2-lipid A biosynthetic process
TPB0596_26750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TPB0596_26850	COG3321	synthase
TPB0596_26850	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_26850	COG0604	alcohol dehydrogenase
TPB0596_26870	COG0706	membrane insertase activity
TPB0596_26930	COG1937	Protein conserved in bacteria
TPB0596_26980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TPB0596_26990	COG3253	May function as heme-dependent peroxidase
TPB0596_27010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TPB0596_27040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TPB0596_27050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TPB0596_27090	COG0756	dUTP diphosphatase activity
TPB0596_27200	COG4770	biotin carboxylase activity
TPB0596_27210	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_27250	COG2267	carboxylic ester hydrolase activity
TPB0596_27260	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_27280	COG1960	acyl-CoA dehydrogenase activity
TPB0596_27290	COG1960	acyl-CoA dehydrogenase activity
TPB0596_27330	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_27340	COG1011	Hydrolase
TPB0596_27360	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_27370	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_27380	COG0183	Belongs to the thiolase family
TPB0596_27420	COG3590	peptidase
TPB0596_27490	COG2890	protein-(glutamine-N5) methyltransferase activity
TPB0596_27520	COG0123	including yeast histone deacetylase and acetoin utilization protein
TPB0596_27620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TPB0596_27660	COG0583	DNA-binding transcription factor activity
TPB0596_27700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TPB0596_27730	COG1643	Atp-dependent helicase
TPB0596_27740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TPB0596_27760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TPB0596_27810	COG1960	acyl-CoA dehydrogenase activity
TPB0596_27820	COG1960	acyl-CoA dehydrogenase activity
TPB0596_27850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TPB0596_27860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TPB0596_27870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TPB0596_27890	COG1196	nuclear chromosome segregation
TPB0596_27920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPB0596_27930	COG1126	abc transporter atp-binding protein
TPB0596_27940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TPB0596_27950	COG0765	amino acid transport
TPB0596_27960	COG0765	amino acid transport
TPB0596_27970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TPB0596_27990	COG2137	regulation of response to DNA damage stimulus
TPB0596_28000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TPB0596_28100	COG1842	Phage shock protein A
TPB0596_28110	COG1396	sequence-specific DNA binding
TPB0596_28120	COG1058	Belongs to the CinA family
TPB0596_28120	COG1546	Belongs to the CinA family
TPB0596_28140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TPB0596_28250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TPB0596_28260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TPB0596_28280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
TPB0596_28360	COG2409	Drug exporters of the RND superfamily
TPB0596_28380	COG3486	L-lysine 6-monooxygenase (NADPH) activity
TPB0596_28420	COG1063	alcohol dehydrogenase
TPB0596_28430	COG1522	sequence-specific DNA binding
TPB0596_28440	COG0686	Belongs to the AlaDH PNT family
TPB0596_28470	COG0584	glycerophosphoryl diester phosphodiesterase
TPB0596_28520	COG1185	polyribonucleotide nucleotidyltransferase activity
TPB0596_28530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TPB0596_28530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TPB0596_28540	COG3540	Alkaline phosphatase
TPB0596_28580	COG1321	iron dependent repressor
TPB0596_28600	COG4607	ABC-type enterochelin transport system periplasmic component
TPB0596_28620	COG0372	Belongs to the citrate synthase family
TPB0596_28640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TPB0596_28660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TPB0596_28670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TPB0596_28760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TPB0596_28770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TPB0596_28790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TPB0596_28790	COG0481	GTPase activity
TPB0596_28820	COG0779	Required for maturation of 30S ribosomal subunits
TPB0596_28890	COG0442	prolyl-tRNA aminoacylation
TPB0596_28900	COG3022	response to hydroperoxide
TPB0596_28940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TPB0596_28940	COG1648	precorrin-2 dehydrogenase activity
TPB0596_29000	COG0579	oxidoreductase
TPB0596_29040	COG1492	cobalamin metabolic process
TPB0596_29090	COG0768	penicillin binding
TPB0596_29150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TPB0596_29160	COG0750	zinc metalloprotease
TPB0596_29170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TPB0596_29200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TPB0596_29210	COG5416	Lipopolysaccharide assembly protein A domain
TPB0596_29230	COG0575	Belongs to the CDS family
TPB0596_29240	COG0233	cytoplasmic translational termination
TPB0596_29250	COG0528	UMP kinase activity
TPB0596_29290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TPB0596_29300	COG0052	Belongs to the universal ribosomal protein uS2 family
TPB0596_29310	COG1115	amino acid carrier protein
TPB0596_29320	COG3226	Transcriptional regulator
TPB0596_29360	COG1823	symporter activity
TPB0596_29380	COG0443	Heat shock 70 kDa protein
TPB0596_29400	COG2814	Major facilitator Superfamily
TPB0596_29410	COG0501	Belongs to the peptidase M48B family
TPB0596_29450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TPB0596_29470	COG4974	Belongs to the 'phage' integrase family
TPB0596_29480	COG0477	Major facilitator Superfamily
TPB0596_29490	COG2011	ABC-type metal ion transport system permease component
TPB0596_29500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TPB0596_29560	COG0792	nuclease activity
TPB0596_29600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TPB0596_29610	COG0681	Belongs to the peptidase S26 family
TPB0596_29620	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_29630	COG0335	large ribosomal subunit rRNA binding
TPB0596_29720	COG0336	Belongs to the RNA methyltransferase TrmD family
TPB0596_29730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TPB0596_29750	COG0228	four-way junction DNA binding
TPB0596_29760	COG0076	glutamate decarboxylase activity
TPB0596_29810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
TPB0596_29920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_29950	COG0829	nickel cation binding
TPB0596_29960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TPB0596_29970	COG0830	nickel cation binding
TPB0596_29980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
TPB0596_29990	COG0804	urea catabolic process
TPB0596_30000	COG0832	Belongs to the urease beta subunit family
TPB0596_30010	COG0831	urea catabolic process
TPB0596_30140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TPB0596_30180	COG1196	nuclear chromosome segregation
TPB0596_30190	COG3766	membrane
TPB0596_30200	COG0754	glutathionylspermidine amidase activity
TPB0596_30220	COG1254	Belongs to the acylphosphatase family
TPB0596_30280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_30330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TPB0596_30340	COG0571	ribonuclease III activity
TPB0596_30360	COG3599	regulation of cell shape
TPB0596_30370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TPB0596_30380	COG0742	ribosomal rna small subunit methyltransferase
TPB0596_30390	COG0477	Major facilitator Superfamily
TPB0596_30430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TPB0596_30440	COG4257	antibiotic catabolic process
TPB0596_30450	COG0456	acetyltransferase
TPB0596_30470	COG1917	Cupin 2, conserved barrel domain protein
TPB0596_30500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TPB0596_30530	COG0477	Major facilitator Superfamily
TPB0596_30540	COG2814	Major facilitator Superfamily
TPB0596_30540	COG0477	Major facilitator Superfamily
TPB0596_30550	COG0598	Magnesium transport protein CorA
TPB0596_30600	COG0740	serine-type endopeptidase activity
TPB0596_30610	COG0740	serine-type endopeptidase activity
TPB0596_30660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_30670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TPB0596_30680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TPB0596_30690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TPB0596_30710	COG1530	ribonuclease E activity
TPB0596_30720	COG0105	UTP biosynthetic process
TPB0596_30740	COG0285	dihydrofolate synthase activity
TPB0596_30750	COG0525	valine-tRNA ligase activity
TPB0596_30760	COG2321	neutral zinc metallopeptidase
TPB0596_30780	COG0488	(ABC) transporter
TPB0596_30800	COG0740	serine-type endopeptidase activity
TPB0596_30810	COG0740	serine-type endopeptidase activity
TPB0596_30820	COG0544	peptidyl-prolyl cis-trans isomerase activity
TPB0596_30840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TPB0596_30920	COG0515	serine threonine protein kinase
TPB0596_30930	COG3135	benzoate transporter
TPB0596_30940	COG1396	sequence-specific DNA binding
TPB0596_30960	COG1120	ATPase activity
TPB0596_30970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPB0596_30990	COG3340	Belongs to the peptidase S51 family
TPB0596_31040	COG2963	transposase activity
TPB0596_31190	COG1024	Enoyl-CoA hydratase
TPB0596_31200	COG1396	sequence-specific DNA binding
TPB0596_31220	COG0531	amino acid
TPB0596_31230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TPB0596_31280	COG2197	response regulator
TPB0596_31370	COG0698	ribose 5-phosphate isomerase
TPB0596_31380	COG0501	Belongs to the peptidase M48B family
TPB0596_31390	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TPB0596_31420	COG3012	SEC-C Motif Domain Protein
TPB0596_31430	COG0477	Major facilitator Superfamily
TPB0596_31440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TPB0596_31470	COG2203	Gaf domain
TPB0596_31470	COG2199	diguanylate cyclase activity
TPB0596_31490	COG0366	Alpha amylase catalytic
TPB0596_31530	COG0824	Thioesterase
TPB0596_31540	COG2902	Dehydrogenase
TPB0596_31610	COG0243	molybdopterin cofactor binding
TPB0596_31630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TPB0596_31630	COG2146	nitrite reductase [NAD(P)H] activity
TPB0596_31640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TPB0596_31640	COG2146	nitrite reductase [NAD(P)H] activity
TPB0596_31730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_31780	COG1131	(ABC) transporter
TPB0596_31820	COG4565	transcriptional regulatory protein
TPB0596_31830	COG3290	protein histidine kinase activity
TPB0596_31840	COG2851	Citrate transporter
TPB0596_31860	COG1695	Transcriptional regulator
TPB0596_31870	COG0446	pyridine nucleotide-disulphide oxidoreductase
TPB0596_31870	COG1902	pentaerythritol trinitrate reductase activity
TPB0596_31880	COG2259	Doxx family
TPB0596_31890	COG0300	oxidoreductase activity
TPB0596_31910	COG0433	COG0433 Predicted ATPase
TPB0596_31930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
TPB0596_32140	COG2963	transposase activity
TPB0596_32210	COG0067	glutamate synthase
TPB0596_32210	COG0069	glutamate synthase activity
TPB0596_32210	COG0070	glutamate synthase
TPB0596_32220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TPB0596_32250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TPB0596_32280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TPB0596_32320	COG3402	PFAM membrane-flanked domain
TPB0596_32330	COG1960	acyl-CoA dehydrogenase activity
TPB0596_32460	COG1846	Transcriptional regulator
TPB0596_32480	COG2963	transposase activity
TPB0596_32600	COG1376	ErfK ybiS ycfS ynhG family protein
TPB0596_32610	COG1252	NADH dehydrogenase
TPB0596_32620	COG0583	DNA-binding transcription factor activity
TPB0596_32650	COG1960	acyl-CoA dehydrogenase activity
TPB0596_32680	COG0439	Biotin carboxylase
TPB0596_32700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TPB0596_32710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TPB0596_32750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TPB0596_32870	COG1316	TRANSCRIPTIONal
TPB0596_32880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TPB0596_32890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TPB0596_32900	COG1234	tRNA 3'-trailer cleavage
TPB0596_32970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TPB0596_32980	COG1335	isochorismatase
TPB0596_32990	COG2267	carboxylic ester hydrolase activity
TPB0596_33040	COG2351	hydroxyisourate hydrolase activity
TPB0596_33060	COG2233	PERMEase
TPB0596_33070	COG3622	Belongs to the hyi family
TPB0596_33080	COG2084	Dehydrogenase
TPB0596_33090	COG3960	tartronate-semialdehyde synthase activity
TPB0596_33100	COG1929	Belongs to the glycerate kinase type-1 family
TPB0596_33140	COG0583	DNA-binding transcription factor activity
TPB0596_33150	COG0477	Major facilitator Superfamily
TPB0596_33180	COG0366	Alpha amylase catalytic
TPB0596_33190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TPB0596_33200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPB0596_33220	COG0579	oxidoreductase
TPB0596_33240	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_33250	COG0657	acetylesterase activity
TPB0596_33260	COG0395	ABC-type sugar transport system, permease component
TPB0596_33270	COG1175	transmembrane transport
TPB0596_33320	COG0183	Belongs to the thiolase family
TPB0596_33360	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TPB0596_33420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TPB0596_33430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TPB0596_33440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TPB0596_33470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TPB0596_33480	COG0356	it plays a direct role in the translocation of protons across the membrane
TPB0596_33500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TPB0596_33510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_33520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_33610	COG2890	protein-(glutamine-N5) methyltransferase activity
TPB0596_33620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TPB0596_33630	COG0254	rRNA binding
TPB0596_33660	COG0083	homoserine kinase activity
TPB0596_33670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TPB0596_33680	COG0460	homoserine dehydrogenase
TPB0596_33940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TPB0596_33950	COG2814	Major facilitator Superfamily
TPB0596_33960	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_34010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TPB0596_34050	COG0567	Dehydrogenase, E1 component
TPB0596_34050	COG0508	dehydrogenase complex catalyzes the overall conversion of
TPB0596_34060	COG1309	transcriptional regulator
TPB0596_34090	COG0598	Magnesium transport protein CorA
TPB0596_34230	COG2239	Acts as a magnesium transporter
TPB0596_34260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TPB0596_34280	COG0531	amino acid
TPB0596_34320	COG1250	3-hydroxyacyl-CoA dehydrogenase
TPB0596_34330	COG1482	cell wall glycoprotein biosynthetic process
TPB0596_34390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TPB0596_34420	COG0300	oxidoreductase activity
TPB0596_34430	COG2226	methyltransferase
TPB0596_34430	COG1073	alpha beta
TPB0596_34440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TPB0596_34450	COG0297	glycogen (starch) synthase activity
TPB0596_34500	COG0789	Transcriptional regulator
TPB0596_34530	COG0463	Glycosyl transferase, family 2
TPB0596_34540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TPB0596_34550	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_34560	COG1611	Belongs to the LOG family
TPB0596_34570	COG1611	Belongs to the LOG family
TPB0596_34580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TPB0596_34590	COG2239	Acts as a magnesium transporter
TPB0596_34650	COG3220	belongs to the UPF0276 family
TPB0596_34680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TPB0596_34700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TPB0596_34720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TPB0596_34730	COG0747	negative chemotaxis
TPB0596_34760	COG0667	Aldo Keto reductase
TPB0596_34780	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TPB0596_34790	COG3842	ATPase activity
TPB0596_34860	COG0738	Major facilitator superfamily
TPB0596_34870	COG1609	Transcriptional regulator
TPB0596_34890	COG1940	carbohydrate kinase activity
TPB0596_34900	COG0058	SHG alpha-glucan phosphorylase activity
TPB0596_34910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TPB0596_34970	COG1960	acyl-CoA dehydrogenase activity
TPB0596_34990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TPB0596_35040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TPB0596_35090	COG0709	Synthesizes selenophosphate from selenide and ATP
TPB0596_35110	COG0437	4 iron, 4 sulfur cluster binding
TPB0596_35120	COG3383	formate dehydrogenase (NAD+) activity
TPB0596_35120	COG0243	molybdopterin cofactor binding
TPB0596_35130	COG3383	formate dehydrogenase (NAD+) activity
TPB0596_35130	COG0243	molybdopterin cofactor binding
TPB0596_35150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TPB0596_35200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TPB0596_35300	COG0456	acetyltransferase
TPB0596_35330	COG2832	Protein of unknown function (DUF454)
TPB0596_35380	COG0604	alcohol dehydrogenase
TPB0596_35410	COG2814	Major facilitator Superfamily
TPB0596_35440	COG1063	alcohol dehydrogenase
TPB0596_35510	COG0012	GTP binding
TPB0596_35530	COG1172	Belongs to the binding-protein-dependent transport system permease family
TPB0596_35550	COG1966	Carbon starvation protein
TPB0596_35580	COG2169	Transcriptional regulator
TPB0596_35580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TPB0596_35590	COG0628	permease
TPB0596_35600	COG1322	Protein conserved in bacteria
TPB0596_35620	COG3599	regulation of cell shape
TPB0596_35650	COG1570	exodeoxyribonuclease VII activity
TPB0596_35720	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TPB0596_35720	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TPB0596_35770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TPB0596_35790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TPB0596_35850	COG1116	anion transmembrane transporter activity
TPB0596_35860	COG4521	taurine ABC transporter
TPB0596_35870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TPB0596_35900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TPB0596_35910	COG1331	Highly conserved protein containing a thioredoxin domain
TPB0596_35930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TPB0596_35950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TPB0596_35980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TPB0596_36030	COG2755	lipolytic protein G-D-S-L family
TPB0596_36110	COG0668	transmembrane transport
TPB0596_36180	COG0148	phosphopyruvate hydratase activity
TPB0596_36220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TPB0596_36230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TPB0596_36270	COG1034	ATP synthesis coupled electron transport
TPB0596_36280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TPB0596_36290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TPB0596_36300	COG0839	Belongs to the complex I subunit 6 family
TPB0596_36320	COG0713	ATP synthesis coupled electron transport
TPB0596_36410	COG3956	TIGRFAM MazG family protein
TPB0596_36430	COG0789	Transcriptional regulator
TPB0596_36490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TPB0596_36520	COG1393	Belongs to the ArsC family
TPB0596_36570	COG2837	iron assimilation
TPB0596_36590	COG0542	response to heat
TPB0596_36650	COG0193	aminoacyl-tRNA hydrolase activity
TPB0596_36660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
TPB0596_36670	COG1250	3-hydroxyacyl-CoA dehydrogenase
TPB0596_36710	COG1280	lysine exporter protein (LysE YggA)
TPB0596_36720	COG1674	ftsk spoiiie
TPB0596_36730	COG1674	ftsk spoiiie
TPB0596_36740	COG1674	ftsk spoiiie
TPB0596_36760	COG1404	Belongs to the peptidase S8 family
TPB0596_36770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TPB0596_36810	COG2963	transposase activity
TPB0596_36830	COG1404	Belongs to the peptidase S8 family
TPB0596_36970	COG0101	tRNA pseudouridine synthase activity
TPB0596_37020	COG0203	ribosomal protein L17
TPB0596_37030	COG0202	RNA polymerase activity
TPB0596_37040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TPB0596_37050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TPB0596_37060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TPB0596_37080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TPB0596_37090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TPB0596_37120	COG0789	Transcriptional regulator
TPB0596_37140	COG0563	adenylate kinase activity
TPB0596_37160	COG0200	Binds to the 23S rRNA
TPB0596_37170	COG1841	ribosomal large subunit assembly
TPB0596_37190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TPB0596_37200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TPB0596_37210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TPB0596_37280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TPB0596_37290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TPB0596_37300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TPB0596_37310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TPB0596_37350	COG0513	Belongs to the DEAD box helicase family
TPB0596_37400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TPB0596_37410	COG0255	Belongs to the universal ribosomal protein uL29 family
TPB0596_37420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TPB0596_37430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TPB0596_37450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TPB0596_37460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TPB0596_37470	COG0089	rRNA binding
TPB0596_37480	COG0088	Forms part of the polypeptide exit tunnel
TPB0596_37490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TPB0596_37500	COG0051	transcription antitermination factor activity, RNA binding
TPB0596_37550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TPB0596_37680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TPB0596_37690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TPB0596_37700	COG0049	tRNA binding
TPB0596_37710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TPB0596_37770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TPB0596_37800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TPB0596_37810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TPB0596_37840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TPB0596_37860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_37910	COG2197	response regulator
TPB0596_37930	COG1131	(ABC) transporter
TPB0596_38030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TPB0596_38140	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_38150	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
TPB0596_38200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TPB0596_38220	COG2072	flavoprotein involved in K transport
TPB0596_38250	COG0657	acetylesterase activity
TPB0596_38260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TPB0596_38270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TPB0596_38310	COG2072	flavoprotein involved in K transport
TPB0596_38330	COG1595	DNA-templated transcription, initiation
TPB0596_38390	COG0438	transferase activity, transferring glycosyl groups
TPB0596_38400	COG3842	ATPase activity
TPB0596_38410	COG1653	transport
TPB0596_38430	COG1175	transmembrane transport
TPB0596_38480	COG2197	response regulator
TPB0596_38530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TPB0596_38570	COG0456	acetyltransferase
TPB0596_38580	COG0745	RESPONSE REGULATOR receiver
TPB0596_38600	COG2897	thiosulfate sulfurtransferase activity
TPB0596_38620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TPB0596_38640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TPB0596_38680	COG0477	Major facilitator Superfamily
TPB0596_38700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TPB0596_38750	COG4044	May play a role in the intracellular transport of hydrophobic ligands
TPB0596_38800	COG0300	oxidoreductase activity
TPB0596_38810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TPB0596_38820	COG4988	ABC transporter
TPB0596_38830	COG1294	oxidase, subunit
TPB0596_38840	COG1271	oxidase subunit
TPB0596_38860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TPB0596_38870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TPB0596_38900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TPB0596_38990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TPB0596_39030	COG5343	regulation of RNA biosynthetic process
TPB0596_39070	COG3706	GGDEF domain
TPB0596_39080	COG1113	amino acid transport
TPB0596_39160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TPB0596_39170	COG1301	dicarboxylic acid transport
TPB0596_39190	COG4565	transcriptional regulatory protein
TPB0596_39200	COG0300	oxidoreductase activity
TPB0596_39220	COG3938	Belongs to the proline racemase family
TPB0596_39230	COG1063	alcohol dehydrogenase
TPB0596_39240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TPB0596_39250	COG1113	amino acid transport
TPB0596_39260	COG1362	aminopeptidase activity
TPB0596_39270	COG0047	phosphoribosylformylglycinamidine synthase activity
TPB0596_39280	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TPB0596_39310	COG0386	Belongs to the glutathione peroxidase family
TPB0596_39330	COG0477	Major facilitator Superfamily
TPB0596_39360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TPB0596_39380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TPB0596_39440	COG2205	protein histidine kinase activity
TPB0596_39450	COG0745	RESPONSE REGULATOR receiver
TPB0596_39480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TPB0596_39550	COG5002	protein histidine kinase activity
TPB0596_39560	COG0745	RESPONSE REGULATOR receiver
TPB0596_39650	COG1024	Enoyl-CoA hydratase
TPB0596_39700	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TPB0596_39720	COG1305	Transglutaminase-like
TPB0596_39740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TPB0596_39810	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TPB0596_39820	COG0788	formyltetrahydrofolate deformylase activity
TPB0596_39870	COG2733	membrane
TPB0596_39880	COG2326	polyphosphate kinase activity
TPB0596_39900	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_39910	COG0583	DNA-binding transcription factor activity
TPB0596_39980	COG2226	methyltransferase
TPB0596_39990	COG0492	ferredoxin-NADP+ reductase activity
TPB0596_40010	COG2224	Isocitrate lyase
TPB0596_40050	COG5285	phytanoyl-CoA dioxygenase
TPB0596_40070	COG1505	serine-type exopeptidase activity
TPB0596_40150	COG2326	polyphosphate kinase activity
TPB0596_40180	COG1535	isochorismatase
TPB0596_40180	COG3433	isochorismatase activity
TPB0596_40190	COG1021	2,3-dihydroxybenzoate-AMP ligase
TPB0596_40200	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_40220	COG1132	(ABC) transporter
TPB0596_40230	COG1132	(ABC) transporter
TPB0596_40240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TPB0596_40250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
TPB0596_40260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TPB0596_40270	COG4607	ABC-type enterochelin transport system periplasmic component
TPB0596_40290	COG1535	isochorismatase
TPB0596_40290	COG3433	isochorismatase activity
TPB0596_40390	COG0326	Molecular chaperone. Has ATPase activity
TPB0596_40450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TPB0596_40500	COG0688	phosphatidylethanolamine metabolic process
TPB0596_40520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TPB0596_40550	COG2111	Na H antiporter
TPB0596_40550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TPB0596_40560	COG0651	ATP synthesis coupled electron transport
TPB0596_40590	COG1320	monovalent cation:proton antiporter activity
TPB0596_40650	COG1120	ATPase activity
TPB0596_40660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPB0596_40750	COG4555	ABC transporter
TPB0596_40770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TPB0596_40780	COG0351	phosphomethylpyrimidine kinase
TPB0596_40800	COG0351	phosphomethylpyrimidine kinase
TPB0596_40870	COG0477	Major facilitator Superfamily
TPB0596_40890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TPB0596_40900	COG2022	thiamine diphosphate biosynthetic process
TPB0596_40920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TPB0596_40920	COG2022	thiamine diphosphate biosynthetic process
TPB0596_40930	COG0352	thiamine-phosphate diphosphorylase activity
TPB0596_40960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TPB0596_40970	COG0515	serine threonine protein kinase
TPB0596_40980	COG1120	ATPase activity
TPB0596_40990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPB0596_41000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPB0596_41030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TPB0596_41050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_41070	COG1132	(ABC) transporter
TPB0596_41130	COG0657	acetylesterase activity
TPB0596_41160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_41200	COG4941	Belongs to the sigma-70 factor family
TPB0596_41220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TPB0596_41240	COG1309	transcriptional regulator
TPB0596_41250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_41260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_41330	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41340	COG3971	2-oxopent-4-enoate hydratase activity
TPB0596_41380	COG1414	Transcriptional regulator
TPB0596_41420	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41430	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TPB0596_41450	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_41500	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_41510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TPB0596_41540	COG2070	2-Nitropropane dioxygenase
TPB0596_41560	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_41620	COG2124	cytochrome p450
TPB0596_41630	COG0183	Belongs to the thiolase family
TPB0596_41640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TPB0596_41650	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_41670	COG1024	Enoyl-CoA hydratase
TPB0596_41720	COG0183	Belongs to the thiolase family
TPB0596_41730	COG1309	transcriptional regulator
TPB0596_41750	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41760	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_41770	COG1024	Enoyl-CoA hydratase
TPB0596_41780	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41790	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41800	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TPB0596_41840	COG0346	lactoylglutathione lyase activity
TPB0596_41850	COG2267	carboxylic ester hydrolase activity
TPB0596_41860	COG1960	acyl-CoA dehydrogenase activity
TPB0596_41870	COG3976	FMN-binding domain protein
TPB0596_41870	COG1053	succinate dehydrogenase
TPB0596_41890	COG1053	succinate dehydrogenase
TPB0596_41900	COG4638	Rieske (2fe-2S)
TPB0596_41930	COG2030	dehydratase
TPB0596_41960	COG1960	acyl-CoA dehydrogenase activity
TPB0596_42050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TPB0596_42320	COG2963	transposase activity
TPB0596_42360	COG2508	Transcriptional regulator
TPB0596_42370	COG2072	flavoprotein involved in K transport
TPB0596_42390	COG0470	DNA polymerase III
TPB0596_42410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TPB0596_42410	COG1754	DNA topoisomerase type I activity
TPB0596_42430	COG1278	Cold shock
TPB0596_42440	COG1205	dead DEAH box helicase
TPB0596_42440	COG1111	helicase
TPB0596_42710	COG4172	Belongs to the ABC transporter superfamily
TPB0596_42720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPB0596_42730	COG0601	transmembrane transport
TPB0596_42750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TPB0596_42760	COG0583	DNA-binding transcription factor activity
TPB0596_42780	COG0156	8-amino-7-oxononanoate synthase activity
TPB0596_42790	COG2814	Major facilitator Superfamily
TPB0596_42800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TPB0596_42870	COG0477	Major facilitator Superfamily
TPB0596_42880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TPB0596_42900	COG0596	Alpha beta hydrolase
TPB0596_42920	COG0494	nUDIX hydrolase
TPB0596_42970	COG2828	Protein conserved in bacteria
TPB0596_42980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPB0596_43040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TPB0596_43060	COG1960	acyl-CoA dehydrogenase activity
TPB0596_43140	COG1396	sequence-specific DNA binding
TPB0596_43160	COG2814	Major facilitator Superfamily
TPB0596_43190	COG2963	transposase activity
TPB0596_43230	COG1408	metallophosphoesterase
TPB0596_43260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TPB0596_43270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TPB0596_43280	COG1764	response to oxidative stress
TPB0596_43330	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_43350	COG0583	DNA-binding transcription factor activity
TPB0596_43370	COG0768	penicillin binding
TPB0596_43400	COG0135	phosphoribosylanthranilate isomerase activity
TPB0596_43430	COG1528	Iron-storage protein
TPB0596_43440	COG1309	transcriptional regulator
TPB0596_43500	COG3251	PFAM MbtH domain protein
TPB0596_43520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TPB0596_43530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TPB0596_43540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TPB0596_43550	COG1017	nitric oxide dioxygenase activity
TPB0596_43550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TPB0596_43560	COG1959	2 iron, 2 sulfur cluster binding
TPB0596_43580	COG4221	oxidoreductase activity
TPB0596_43600	COG2807	transmembrane transport
TPB0596_43640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TPB0596_43710	COG0860	N-Acetylmuramoyl-L-alanine amidase
TPB0596_43720	COG0564	pseudouridine synthase activity
TPB0596_43750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TPB0596_43790	COG1785	Belongs to the alkaline phosphatase family
TPB0596_43820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPB0596_43900	COG0596	Alpha beta hydrolase
TPB0596_43940	COG3391	amine dehydrogenase activity
TPB0596_43940	COG5651	PPE family
TPB0596_43960	COG0640	Transcriptional regulator
TPB0596_43990	COG1793	dna ligase
TPB0596_44000	COG2318	DinB family
TPB0596_44020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TPB0596_44050	COG2409	Drug exporters of the RND superfamily
TPB0596_44110	COG0287	Prephenate dehydrogenase
TPB0596_44210	COG0739	heme binding
TPB0596_44230	COG2197	response regulator
TPB0596_44290	COG2963	transposase activity
TPB0596_44410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TPB0596_44450	COG4977	sequence-specific DNA binding
TPB0596_44490	COG2030	dehydratase
TPB0596_44530	COG0385	Bile acid
TPB0596_44570	COG1024	Enoyl-CoA hydratase
TPB0596_44580	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_44600	COG1309	transcriptional regulator
TPB0596_44630	COG0596	Alpha beta hydrolase
TPB0596_44710	COG0183	Belongs to the thiolase family
TPB0596_44720	COG3321	synthase
TPB0596_44720	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_44720	COG0604	alcohol dehydrogenase
TPB0596_44790	COG1216	Glycosyl transferase, family 2
TPB0596_44800	COG0318	PFAM AMP-dependent synthetase and ligase
TPB0596_44860	COG1476	TRANSCRIPTIONal
TPB0596_44880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TPB0596_44890	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_44900	COG0006	proline dipeptidase activity
TPB0596_44910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TPB0596_44920	COG1473	amidohydrolase
TPB0596_44940	COG1960	acyl-CoA dehydrogenase activity
TPB0596_44950	COG1309	transcriptional regulator
TPB0596_44970	COG1028	Short-chain dehydrogenase reductase Sdr
TPB0596_45020	COG4221	oxidoreductase activity
TPB0596_45030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TPB0596_45060	COG1122	ATPase activity
TPB0596_45070	COG1268	BioY protein
TPB0596_45090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TPB0596_45170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TPB0596_45220	COG1174	glycine betaine transport
TPB0596_45240	COG1174	glycine betaine transport
TPB0596_45250	COG3973	AAA domain
TPB0596_45360	COG0477	Major facilitator Superfamily
TPB0596_45370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TPB0596_45410	COG2267	carboxylic ester hydrolase activity
TPB0596_45420	COG2508	Transcriptional regulator
TPB0596_45460	COG3971	2-oxopent-4-enoate hydratase activity
TPB0596_45470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TPB0596_45480	COG0346	lactoylglutathione lyase activity
TPB0596_45510	COG0305	Participates in initiation and elongation during chromosome replication
TPB0596_45570	COG0360	Binds together with S18 to 16S ribosomal RNA
TPB0596_45590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TPB0596_45700	COG1309	transcriptional regulator
TPB0596_45740	COG0183	Belongs to the thiolase family
TPB0596_45750	COG1024	Enoyl-CoA hydratase
TPB0596_45750	COG1250	3-hydroxyacyl-CoA dehydrogenase
TPB0596_45790	COG1024	Enoyl-CoA hydratase
TPB0596_45850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TPB0596_45880	COG1260	myo-inositol-1-phosphate synthase
TPB0596_46000	COG1358	cellular component organization or biogenesis
TPB0596_46030	COG1297	OPT oligopeptide transporter protein
TPB0596_46080	COG2814	Major facilitator Superfamily
TPB0596_46090	COG0569	domain protein
TPB0596_46100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TPB0596_46110	COG4221	oxidoreductase activity
TPB0596_46120	COG4122	O-methyltransferase activity
TPB0596_46170	COG0495	leucyl-tRNA aminoacylation
TPB0596_46270	COG0617	tRNA 3'-terminal CCA addition
TPB0596_46320	COG0519	Catalyzes the synthesis of GMP from XMP
TPB0596_46330	COG1012	belongs to the aldehyde dehydrogenase family
TPB0596_46580	COG0860	N-Acetylmuramoyl-L-alanine amidase
TPB0596_46580	COG3409	Peptidoglycan-binding domain 1 protein
TPB0596_46610	COG1192	Involved in chromosome partitioning
TPB0596_46620	COG0357	Ribosomal RNA small subunit methyltransferase G
TPB0596_46640	COG0706	membrane insertase activity
TPB0596_46650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TPB0596_46660	COG0594	ribonuclease P activity