locus-tag	class	description
MTP03_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MTP03_00040	COG0592	DNA-directed DNA polymerase activity
MTP03_00050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MTP03_00070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTP03_00120	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MTP03_00130	COG0187	DNA topoisomerase II activity
MTP03_00140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MTP03_00160	COG4974	Belongs to the 'phage' integrase family
MTP03_00270	COG3634	alkyl hydroperoxide reductase activity
MTP03_00350	COG2815	serine threonine protein kinase
MTP03_00350	COG0515	serine threonine protein kinase
MTP03_00360	COG0768	penicillin binding
MTP03_00410	COG1716	ATPase activity
MTP03_00460	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_00470	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_00520	COG1309	transcriptional regulator
MTP03_00530	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_00570	COG4221	oxidoreductase activity
MTP03_00610	COG1073	alpha beta
MTP03_00660	COG3336	cytochrome c oxidase
MTP03_00690	COG0657	acetylesterase activity
MTP03_00730	COG0778	Nitroreductase
MTP03_00740	COG1376	ErfK ybiS ycfS ynhG family protein
MTP03_00760	COG0640	Transcriptional regulator
MTP03_00800	COG0745	RESPONSE REGULATOR receiver
MTP03_00810	COG2205	protein histidine kinase activity
MTP03_00820	COG5002	protein histidine kinase activity
MTP03_00840	COG3559	Exporter of polyketide antibiotics
MTP03_00850	COG1131	(ABC) transporter
MTP03_00900	COG0667	Aldo Keto reductase
MTP03_00910	COG0667	Aldo Keto reductase
MTP03_00940	COG0067	glutamate synthase
MTP03_00940	COG0069	glutamate synthase activity
MTP03_00940	COG0070	glutamate synthase
MTP03_01000	COG2501	S4 domain
MTP03_01020	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_01290	COG1316	TRANSCRIPTIONal
MTP03_01310	COG2252	PERMEase
MTP03_01330	COG3226	Transcriptional regulator
MTP03_01440	COG0813	purine-nucleoside phosphorylase activity
MTP03_01480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MTP03_01510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MTP03_01510	COG2146	nitrite reductase [NAD(P)H] activity
MTP03_01540	COG0561	phosphatase activity
MTP03_01550	COG2385	sporulation resulting in formation of a cellular spore
MTP03_01570	COG1216	Glycosyl transferase, family 2
MTP03_01580	COG0671	phosphoesterase, PA-phosphatase related
MTP03_01590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MTP03_01600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MTP03_01660	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MTP03_01680	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MTP03_01690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_01700	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_01710	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_01720	COG3321	synthase
MTP03_01720	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MTP03_01720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTP03_01730	COG3321	synthase
MTP03_01730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTP03_01730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MTP03_01740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_01750	COG0277	FAD linked oxidase domain protein
MTP03_01800	COG1956	GAF domain-containing protein
MTP03_01860	COG2353	YceI-like domain
MTP03_01880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MTP03_01900	COG1349	DNA-binding transcription factor activity
MTP03_01910	COG1105	Belongs to the carbohydrate kinase PfkB family
MTP03_01920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTP03_01920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTP03_01980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTP03_02000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MTP03_02010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MTP03_02100	COG1846	Transcriptional regulator
MTP03_02210	COG1396	sequence-specific DNA binding
MTP03_02220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MTP03_02230	COG1760	l-serine dehydratase
MTP03_02260	COG3214	Protein conserved in bacteria
MTP03_02280	COG0659	secondary active sulfate transmembrane transporter activity
MTP03_02300	COG0488	(ABC) transporter
MTP03_02350	COG0778	Nitroreductase
MTP03_02370	COG0183	Belongs to the thiolase family
MTP03_02380	COG0183	Belongs to the thiolase family
MTP03_02400	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP03_02400	COG1024	Enoyl-CoA hydratase
MTP03_02540	COG1309	transcriptional regulator
MTP03_02590	COG2409	Drug exporters of the RND superfamily
MTP03_02610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MTP03_02680	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MTP03_02700	COG1476	TRANSCRIPTIONal
MTP03_02750	COG1454	alcohol dehydrogenase
MTP03_02770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MTP03_02850	COG0535	radical SAM domain protein
MTP03_02910	COG1136	(ABC) transporter
MTP03_02910	COG0577	efflux transmembrane transporter activity
MTP03_02990	COG0492	ferredoxin-NADP+ reductase activity
MTP03_03110	COG4981	capsule polysaccharide biosynthetic process
MTP03_03120	COG4981	capsule polysaccharide biosynthetic process
MTP03_03160	COG1472	Belongs to the glycosyl hydrolase 3 family
MTP03_03170	COG1309	transcriptional regulator
MTP03_03180	COG2030	dehydratase
MTP03_03190	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_03200	COG0183	Belongs to the thiolase family
MTP03_03210	COG1832	CoA-binding protein
MTP03_03270	COG1960	acyl-CoA dehydrogenase activity
MTP03_03310	COG0477	Major facilitator Superfamily
MTP03_03320	COG1115	amino acid carrier protein
MTP03_03340	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_03370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MTP03_03370	COG2066	Belongs to the glutaminase family
MTP03_03380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTP03_03400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MTP03_03550	COG0247	lactate metabolic process
MTP03_03550	COG2181	nitrate reductase activity
MTP03_03560	COG2181	nitrate reductase activity
MTP03_03560	COG0247	lactate metabolic process
MTP03_03600	COG0708	Exodeoxyribonuclease III
MTP03_03700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MTP03_03760	COG1454	alcohol dehydrogenase
MTP03_03790	COG0145	ligase activity
MTP03_03800	COG0145	ligase activity
MTP03_03830	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP03_03860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTP03_03900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MTP03_03910	COG0484	heat shock protein binding
MTP03_03920	COG0789	Transcriptional regulator
MTP03_03930	COG0789	Transcriptional regulator
MTP03_04040	COG0542	response to heat
MTP03_04050	COG0493	'glutamate synthase
MTP03_04050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MTP03_04070	COG2267	carboxylic ester hydrolase activity
MTP03_04100	COG2149	membrane
MTP03_04140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTP03_04160	COG0488	(ABC) transporter
MTP03_04170	COG0488	(ABC) transporter
MTP03_04180	COG0586	Pfam SNARE associated Golgi protein
MTP03_04210	COG0025	NhaP-type Na H and K H
MTP03_04270	COG4129	membrane
MTP03_04290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MTP03_04330	COG2814	Major facilitator Superfamily
MTP03_04340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MTP03_04380	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_04460	COG1690	Belongs to the RtcB family
MTP03_04470	COG3226	Transcriptional regulator
MTP03_04530	COG0442	prolyl-tRNA aminoacylation
MTP03_04550	COG0343	queuine tRNA-ribosyltransferase activity
MTP03_04580	COG2027	D-alanyl-D-alanine carboxypeptidase
MTP03_04610	COG0037	tRNA processing
MTP03_04620	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MTP03_04650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP03_04660	COG0302	gtp cyclohydrolase
MTP03_04670	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTP03_04680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MTP03_04730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MTP03_04740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MTP03_04750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MTP03_04770	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MTP03_04790	COG0542	response to heat
MTP03_04810	COG0542	response to heat
MTP03_04820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTP03_04850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP03_04970	COG1194	a g-specific adenine glycosylase
MTP03_04980	COG0288	reversible hydration of carbon dioxide
MTP03_05010	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MTP03_05020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MTP03_05050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MTP03_05090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTP03_05110	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MTP03_05120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MTP03_05130	COG1116	anion transmembrane transporter activity
MTP03_05190	COG0438	transferase activity, transferring glycosyl groups
MTP03_05220	COG0477	Major facilitator Superfamily
MTP03_05240	COG0363	glucosamine-6-phosphate deaminase activity
MTP03_05250	COG0363	glucosamine-6-phosphate deaminase activity
MTP03_05280	COG0477	Major facilitator Superfamily
MTP03_05300	COG0640	Transcriptional regulator
MTP03_05320	COG0667	Aldo Keto reductase
MTP03_05330	COG0789	Transcriptional regulator
MTP03_05370	COG4106	trans-aconitate 2-methyltransferase activity
MTP03_05380	COG0583	DNA-binding transcription factor activity
MTP03_05390	COG2814	Major facilitator Superfamily
MTP03_05400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_05430	COG0588	phosphoglycerate mutase activity
MTP03_05450	COG5002	protein histidine kinase activity
MTP03_05460	COG0745	RESPONSE REGULATOR receiver
MTP03_05530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTP03_05590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MTP03_05600	COG0181	hydroxymethylbilane synthase activity
MTP03_05680	COG2608	mercury ion transmembrane transporter activity
MTP03_05690	COG2954	triphosphatase activity
MTP03_05700	COG2409	Drug exporters of the RND superfamily
MTP03_05740	COG2337	Toxic component of a toxin-antitoxin (TA) module
MTP03_05760	COG3540	Alkaline phosphatase
MTP03_05770	COG2272	Belongs to the type-B carboxylesterase lipase family
MTP03_05810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MTP03_05820	COG0406	alpha-ribazole phosphatase activity
MTP03_05840	COG0785	Cytochrome C biogenesis protein
MTP03_05860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MTP03_05890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTP03_05910	COG1960	acyl-CoA dehydrogenase activity
MTP03_06040	COG4948	Mandelate Racemase Muconate Lactonizing
MTP03_06070	COG1309	transcriptional regulator
MTP03_06080	COG0154	amidase activity
MTP03_06110	COG1937	Protein conserved in bacteria
MTP03_06120	COG3268	Saccharopine dehydrogenase
MTP03_06150	COG3180	Ammonia monooxygenase
MTP03_06190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MTP03_06220	COG0438	transferase activity, transferring glycosyl groups
MTP03_06230	COG2226	methyltransferase
MTP03_06240	COG0142	geranyltranstransferase activity
MTP03_06250	COG0501	Belongs to the peptidase M48B family
MTP03_06280	COG1666	GTP binding
MTP03_06300	COG2030	dehydratase
MTP03_06310	COG2030	dehydratase
MTP03_06320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTP03_06340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MTP03_06350	COG0081	regulation of translation
MTP03_06480	COG3304	Inner membrane component domain
MTP03_06550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP03_06640	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_06690	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_06720	COG2508	Transcriptional regulator
MTP03_06740	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_06760	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_06780	COG1073	alpha beta
MTP03_06790	COG0778	Nitroreductase
MTP03_06810	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MTP03_06840	COG2301	Belongs to the HpcH HpaI aldolase family
MTP03_06850	COG1960	acyl-CoA dehydrogenase activity
MTP03_06880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTP03_06890	COG1960	acyl-CoA dehydrogenase activity
MTP03_06900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_06960	COG1960	acyl-CoA dehydrogenase activity
MTP03_06980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MTP03_07000	COG2814	Major facilitator Superfamily
MTP03_07010	COG2814	Major facilitator Superfamily
MTP03_07040	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_07050	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_07060	COG1063	alcohol dehydrogenase
MTP03_07090	COG0145	ligase activity
MTP03_07140	COG1063	alcohol dehydrogenase
MTP03_07190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_07220	COG2376	Dihydroxyacetone kinase
MTP03_07290	COG2301	Belongs to the HpcH HpaI aldolase family
MTP03_07370	COG0765	amino acid transport
MTP03_07380	COG1126	abc transporter atp-binding protein
MTP03_07390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MTP03_07400	COG1263	PTS System
MTP03_07410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTP03_07420	COG2190	(PTS) system
MTP03_07420	COG1263	PTS System
MTP03_07420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTP03_07450	COG2188	Transcriptional regulator
MTP03_07480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_07580	COG1061	Type III restriction enzyme res subunit
MTP03_07630	COG4941	Belongs to the sigma-70 factor family
MTP03_07720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTP03_07760	COG2814	Major facilitator Superfamily
MTP03_07830	COG0671	phosphoesterase, PA-phosphatase related
MTP03_07850	COG1846	Transcriptional regulator
MTP03_07930	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MTP03_07950	COG0259	pyridoxamine-phosphate oxidase activity
MTP03_07980	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_08020	COG0545	Peptidyl-prolyl cis-trans isomerase
MTP03_08090	COG4249	Peptidase C14 caspase catalytic subunit p20
MTP03_08090	COG2319	Wd-40 repeat
MTP03_08120	COG0656	L-ascorbic acid biosynthetic process
MTP03_08130	COG0656	L-ascorbic acid biosynthetic process
MTP03_08200	COG1408	metallophosphoesterase
MTP03_08210	COG1408	metallophosphoesterase
MTP03_08230	COG0328	RNA-DNA hybrid ribonuclease activity
MTP03_08280	COG1218	3'(2'),5'-bisphosphate nucleotidase
MTP03_08290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP03_08300	COG2259	Doxx family
MTP03_08310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_08330	COG2364	Membrane
MTP03_08360	COG0166	Belongs to the GPI family
MTP03_08490	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_08500	COG0739	heme binding
MTP03_08530	COG1285	pathogenesis
MTP03_08550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_08570	COG1960	acyl-CoA dehydrogenase activity
MTP03_08600	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_08610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTP03_08710	COG0045	succinate-CoA ligase (ADP-forming) activity
MTP03_08780	COG0640	Transcriptional regulator
MTP03_08810	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
MTP03_08870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MTP03_08880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MTP03_08890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MTP03_08910	COG2860	membrane
MTP03_08940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTP03_08950	COG0521	Mo-molybdopterin cofactor biosynthetic process
MTP03_09050	COG1970	mechanosensitive ion channel activity
MTP03_09120	COG1309	transcriptional regulator
MTP03_09140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MTP03_09150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTP03_09170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTP03_09200	COG1733	regulation of RNA biosynthetic process
MTP03_09210	COG2259	Doxx family
MTP03_09240	COG5473	translation initiation factor activity
MTP03_09250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MTP03_09280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP03_09380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MTP03_09390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MTP03_09400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MTP03_09410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MTP03_09430	COG0477	Major facilitator Superfamily
MTP03_09530	COG0084	hydrolase, TatD family'
MTP03_09540	COG3583	domain protein
MTP03_09550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MTP03_09560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MTP03_09610	COG0488	(ABC) transporter
MTP03_09640	COG0574	Belongs to the PEP-utilizing enzyme family
MTP03_09640	COG3848	Pyruvate phosphate dikinase
MTP03_09650	COG3848	Pyruvate phosphate dikinase
MTP03_09650	COG0574	Belongs to the PEP-utilizing enzyme family
MTP03_09660	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_09670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTP03_09760	COG1280	lysine exporter protein (LysE YggA)
MTP03_09770	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_09830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MTP03_09840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MTP03_09850	COG0193	aminoacyl-tRNA hydrolase activity
MTP03_09930	COG2837	iron assimilation
MTP03_10000	COG1393	Belongs to the ArsC family
MTP03_10020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MTP03_10090	COG0789	Transcriptional regulator
MTP03_10110	COG3956	TIGRFAM MazG family protein
MTP03_10160	COG1073	alpha beta
MTP03_10240	COG0839	Belongs to the complex I subunit 6 family
MTP03_10250	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTP03_10280	COG1034	ATP synthesis coupled electron transport
MTP03_10320	COG0649	NAD binding
MTP03_10330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTP03_10340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTP03_10350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTP03_10390	COG0148	phosphopyruvate hydratase activity
MTP03_10470	COG0668	transmembrane transport
MTP03_10550	COG2755	lipolytic protein G-D-S-L family
MTP03_10610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MTP03_10640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTP03_10670	COG3177	Filamentation induced by cAMP protein fic
MTP03_10710	COG1331	Highly conserved protein containing a thioredoxin domain
MTP03_10740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MTP03_10750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MTP03_10780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP03_10790	COG4521	taurine ABC transporter
MTP03_10800	COG1116	anion transmembrane transporter activity
MTP03_10850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MTP03_10880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MTP03_10910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MTP03_10910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MTP03_10990	COG1570	exodeoxyribonuclease VII activity
MTP03_11050	COG1322	Protein conserved in bacteria
MTP03_11060	COG0628	permease
MTP03_11070	COG2169	Transcriptional regulator
MTP03_11070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTP03_11100	COG1966	Carbon starvation protein
MTP03_11110	COG0012	GTP binding
MTP03_11200	COG2824	Alkylphosphonate utilization operon protein PhnA
MTP03_11250	COG2814	Major facilitator Superfamily
MTP03_11310	COG0604	alcohol dehydrogenase
MTP03_11360	COG2832	Protein of unknown function (DUF454)
MTP03_11390	COG1846	Transcriptional regulator
MTP03_11560	COG0437	4 iron, 4 sulfur cluster binding
MTP03_11580	COG0709	Synthesizes selenophosphate from selenide and ATP
MTP03_11650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTP03_11670	COG1960	acyl-CoA dehydrogenase activity
MTP03_11680	COG1960	acyl-CoA dehydrogenase activity
MTP03_11720	COG0469	pyruvate kinase activity
MTP03_11730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTP03_11740	COG1940	carbohydrate kinase activity
MTP03_11760	COG1940	carbohydrate kinase activity
MTP03_11800	COG1609	Transcriptional regulator
MTP03_11820	COG0738	Major facilitator superfamily
MTP03_11840	COG1051	belongs to the nudix hydrolase family
MTP03_11870	COG3842	ATPase activity
MTP03_11880	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MTP03_11900	COG0667	Aldo Keto reductase
MTP03_11930	COG1252	NADH dehydrogenase
MTP03_11960	COG0747	negative chemotaxis
MTP03_11970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTP03_11980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTP03_12000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MTP03_12010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTP03_12040	COG3220	belongs to the UPF0276 family
MTP03_12070	COG2239	Acts as a magnesium transporter
MTP03_12080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP03_12090	COG1611	Belongs to the LOG family
MTP03_12100	COG1611	Belongs to the LOG family
MTP03_12110	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_12120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTP03_12130	COG0463	Glycosyl transferase, family 2
MTP03_12140	COG0463	Glycosyl transferase, family 2
MTP03_12230	COG0297	glycogen (starch) synthase activity
MTP03_12240	COG0297	glycogen (starch) synthase activity
MTP03_12250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MTP03_12280	COG2226	methyltransferase
MTP03_12280	COG1073	alpha beta
MTP03_12290	COG0300	oxidoreductase activity
MTP03_12320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MTP03_12370	COG1482	cell wall glycoprotein biosynthetic process
MTP03_12410	COG1132	(ABC) transporter
MTP03_12420	COG0531	amino acid
MTP03_12430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MTP03_12460	COG2239	Acts as a magnesium transporter
MTP03_12620	COG0598	Magnesium transport protein CorA
MTP03_12650	COG1309	transcriptional regulator
MTP03_12660	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP03_12660	COG0567	Dehydrogenase, E1 component
MTP03_12710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP03_12750	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_12770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MTP03_12820	COG0018	arginyl-trna synthetase
MTP03_12840	COG0460	homoserine dehydrogenase
MTP03_12850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MTP03_12860	COG0083	homoserine kinase activity
MTP03_12900	COG0254	rRNA binding
MTP03_12910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MTP03_12920	COG2890	protein-(glutamine-N5) methyltransferase activity
MTP03_13040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTP03_13050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTP03_13060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTP03_13080	COG0356	it plays a direct role in the translocation of protons across the membrane
MTP03_13090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MTP03_13120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MTP03_13130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MTP03_13140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MTP03_13150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MTP03_13190	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MTP03_13240	COG0183	Belongs to the thiolase family
MTP03_13250	COG0183	Belongs to the thiolase family
MTP03_13280	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_13320	COG0657	acetylesterase activity
MTP03_13330	COG1126	abc transporter atp-binding protein
MTP03_13340	COG0765	amino acid transport
MTP03_13350	COG0765	amino acid transport
MTP03_13370	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_13380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MTP03_13390	COG0657	acetylesterase activity
MTP03_13420	COG2072	flavoprotein involved in K transport
MTP03_13440	COG0579	oxidoreductase
MTP03_13470	COG1403	HNH endonuclease
MTP03_13480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTP03_13490	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MTP03_13500	COG0366	Alpha amylase catalytic
MTP03_13530	COG0477	Major facilitator Superfamily
MTP03_13540	COG0477	Major facilitator Superfamily
MTP03_13550	COG1929	Belongs to the glycerate kinase type-1 family
MTP03_13560	COG3960	tartronate-semialdehyde synthase activity
MTP03_13580	COG2084	Dehydrogenase
MTP03_13590	COG2084	Dehydrogenase
MTP03_13600	COG3622	Belongs to the hyi family
MTP03_13610	COG2233	PERMEase
MTP03_13630	COG2351	hydroxyisourate hydrolase activity
MTP03_13690	COG1335	isochorismatase
MTP03_13700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MTP03_13760	COG0705	Rhomboid family
MTP03_13770	COG1234	tRNA 3'-trailer cleavage
MTP03_13780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MTP03_13790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MTP03_13810	COG1316	TRANSCRIPTIONal
MTP03_13860	COG1022	Amp-dependent synthetase and ligase
MTP03_13950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MTP03_13980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MTP03_14000	COG0439	Biotin carboxylase
MTP03_14020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTP03_14050	COG1960	acyl-CoA dehydrogenase activity
MTP03_14080	COG0583	DNA-binding transcription factor activity
MTP03_14090	COG1252	NADH dehydrogenase
MTP03_14110	COG1376	ErfK ybiS ycfS ynhG family protein
MTP03_14130	COG1960	acyl-CoA dehydrogenase activity
MTP03_14270	COG3402	PFAM membrane-flanked domain
MTP03_14340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTP03_14380	COG4941	Belongs to the sigma-70 factor family
MTP03_14390	COG3795	YCII-related domain
MTP03_14400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MTP03_14420	COG0433	COG0433 Predicted ATPase
MTP03_14430	COG0300	oxidoreductase activity
MTP03_14500	COG0477	Major facilitator Superfamily
MTP03_14510	COG0477	Major facilitator Superfamily
MTP03_14520	COG3618	amidohydrolase
MTP03_14540	COG0667	Aldo Keto reductase
MTP03_14580	COG0657	acetylesterase activity
MTP03_14590	COG2084	Dehydrogenase
MTP03_14620	COG0667	Aldo Keto reductase
MTP03_14630	COG1960	acyl-CoA dehydrogenase activity
MTP03_14640	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_14650	COG0183	Belongs to the thiolase family
MTP03_14700	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_14710	COG1024	Enoyl-CoA hydratase
MTP03_14760	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP03_14770	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP03_14780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MTP03_14790	COG1960	acyl-CoA dehydrogenase activity
MTP03_14800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_14810	COG1024	Enoyl-CoA hydratase
MTP03_14840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_14920	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_14930	COG0477	Major facilitator Superfamily
MTP03_14960	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MTP03_14980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTP03_14980	COG1263	PTS System
MTP03_14980	COG2190	(PTS) system
MTP03_14990	COG2190	(PTS) system
MTP03_14990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTP03_14990	COG1263	PTS System
MTP03_15000	COG2723	6-phospho-beta-galactosidase activity
MTP03_15040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MTP03_15060	COG2226	methyltransferase
MTP03_15070	COG1252	NADH dehydrogenase
MTP03_15080	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTP03_15080	COG1902	pentaerythritol trinitrate reductase activity
MTP03_15090	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTP03_15090	COG1902	pentaerythritol trinitrate reductase activity
MTP03_15100	COG1695	Transcriptional regulator
MTP03_15340	COG2851	Citrate transporter
MTP03_15350	COG3290	protein histidine kinase activity
MTP03_15360	COG4565	transcriptional regulatory protein
MTP03_15390	COG3177	Filamentation induced by cAMP protein fic
MTP03_15410	COG1131	(ABC) transporter
MTP03_15420	COG1131	(ABC) transporter
MTP03_15470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_15610	COG2146	nitrite reductase [NAD(P)H] activity
MTP03_15610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP03_15620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP03_15630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP03_15660	COG0243	molybdopterin cofactor binding
MTP03_15700	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_15700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MTP03_15700	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_15700	COG0300	oxidoreductase activity
MTP03_15700	COG3321	synthase
MTP03_15730	COG2902	Dehydrogenase
MTP03_15740	COG2902	Dehydrogenase
MTP03_15750	COG2902	Dehydrogenase
MTP03_15760	COG0824	Thioesterase
MTP03_15840	COG0366	Alpha amylase catalytic
MTP03_15870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MTP03_15890	COG3012	SEC-C Motif Domain Protein
MTP03_15930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MTP03_15940	COG0501	Belongs to the peptidase M48B family
MTP03_15950	COG0698	ribose 5-phosphate isomerase
MTP03_16030	COG0477	Major facilitator Superfamily
MTP03_16100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTP03_16120	COG2267	carboxylic ester hydrolase activity
MTP03_16160	COG2197	response regulator
MTP03_16190	COG2124	cytochrome p450
MTP03_16230	COG0531	amino acid
MTP03_16270	COG1024	Enoyl-CoA hydratase
MTP03_16290	COG0477	Major facilitator Superfamily
MTP03_16450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_16460	COG1120	ATPase activity
MTP03_16480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP03_16530	COG3135	benzoate transporter
MTP03_16540	COG0515	serine threonine protein kinase
MTP03_16590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP03_16640	COG0544	peptidyl-prolyl cis-trans isomerase activity
MTP03_16660	COG0740	serine-type endopeptidase activity
MTP03_16680	COG0488	(ABC) transporter
MTP03_16710	COG0525	valine-tRNA ligase activity
MTP03_16720	COG0285	dihydrofolate synthase activity
MTP03_16750	COG1530	ribonuclease E activity
MTP03_16750	COG1530	ribonuclease E activity
MTP03_16770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MTP03_16780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MTP03_16790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MTP03_16800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MTP03_16830	COG0740	serine-type endopeptidase activity
MTP03_16840	COG0740	serine-type endopeptidase activity
MTP03_16880	COG1472	Belongs to the glycosyl hydrolase 3 family
MTP03_16900	COG0598	Magnesium transport protein CorA
MTP03_16920	COG1846	Transcriptional regulator
MTP03_16980	COG0028	Belongs to the TPP enzyme family
MTP03_16990	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_17050	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_17060	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_17080	COG0477	Major facilitator Superfamily
MTP03_17090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MTP03_17120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP03_17130	COG0456	acetyltransferase
MTP03_17150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTP03_17160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTP03_17200	COG0477	Major facilitator Superfamily
MTP03_17210	COG0742	ribosomal rna small subunit methyltransferase
MTP03_17230	COG3599	regulation of cell shape
MTP03_17250	COG0571	ribonuclease III activity
MTP03_17260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MTP03_17310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_17320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_17360	COG1254	Belongs to the acylphosphatase family
MTP03_17380	COG0754	glutathionylspermidine amidase activity
MTP03_17390	COG3766	membrane
MTP03_17430	COG1196	nuclear chromosome segregation
MTP03_17440	COG1196	nuclear chromosome segregation
MTP03_17460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MTP03_17510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MTP03_17560	COG0831	urea catabolic process
MTP03_17570	COG0832	Belongs to the urease beta subunit family
MTP03_17580	COG0804	urea catabolic process
MTP03_17590	COG0804	urea catabolic process
MTP03_17600	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MTP03_17610	COG0830	nickel cation binding
MTP03_17620	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MTP03_17630	COG0829	nickel cation binding
MTP03_17660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_17670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTP03_17720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MTP03_17730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MTP03_17790	COG0228	four-way junction DNA binding
MTP03_17810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MTP03_17820	COG0336	Belongs to the RNA methyltransferase TrmD family
MTP03_17910	COG0335	large ribosomal subunit rRNA binding
MTP03_17920	COG0681	Belongs to the peptidase S26 family
MTP03_17930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MTP03_18040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTP03_18050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTP03_18060	COG2011	ABC-type metal ion transport system permease component
MTP03_18090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MTP03_18110	COG0501	Belongs to the peptidase M48B family
MTP03_18120	COG2814	Major facilitator Superfamily
MTP03_18150	COG0443	Heat shock 70 kDa protein
MTP03_18170	COG1823	symporter activity
MTP03_18200	COG1115	amino acid carrier protein
MTP03_18210	COG0052	Belongs to the universal ribosomal protein uS2 family
MTP03_18220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MTP03_18290	COG0233	cytoplasmic translational termination
MTP03_18340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MTP03_18390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MTP03_18480	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_18490	COG0768	penicillin binding
MTP03_18550	COG1492	cobalamin metabolic process
MTP03_18590	COG0579	oxidoreductase
MTP03_18600	COG0579	oxidoreductase
MTP03_18670	COG1554	hydrolase, family 65, central catalytic
MTP03_18710	COG0477	Major facilitator Superfamily
MTP03_18720	COG1940	carbohydrate kinase activity
MTP03_18740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MTP03_18740	COG1648	precorrin-2 dehydrogenase activity
MTP03_18790	COG3022	response to hydroperoxide
MTP03_18800	COG0442	prolyl-tRNA aminoacylation
MTP03_18850	COG0779	Required for maturation of 30S ribosomal subunits
MTP03_18890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MTP03_18890	COG0481	GTPase activity
MTP03_18910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MTP03_18920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MTP03_18990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTP03_19010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MTP03_19020	COG2977	Belongs to the P-Pant transferase superfamily
MTP03_19030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MTP03_19040	COG0372	Belongs to the citrate synthase family
MTP03_19080	COG1321	iron dependent repressor
MTP03_19100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MTP03_19130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MTP03_19130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MTP03_19140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MTP03_19140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MTP03_19160	COG1185	polyribonucleotide nucleotidyltransferase activity
MTP03_19170	COG0612	Peptidase, M16
MTP03_19190	COG0584	glycerophosphoryl diester phosphodiesterase
MTP03_19220	COG0686	Belongs to the AlaDH PNT family
MTP03_19230	COG1522	sequence-specific DNA binding
MTP03_19240	COG1063	alcohol dehydrogenase
MTP03_19250	COG1741	Belongs to the pirin family
MTP03_19320	COG2409	Drug exporters of the RND superfamily
MTP03_19330	COG2409	Drug exporters of the RND superfamily
MTP03_19360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MTP03_19430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MTP03_19450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTP03_19460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MTP03_19550	COG2890	protein-(glutamine-N5) methyltransferase activity
MTP03_19590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MTP03_19610	COG1058	Belongs to the CinA family
MTP03_19610	COG1546	Belongs to the CinA family
MTP03_19620	COG1396	sequence-specific DNA binding
MTP03_19630	COG1842	Phage shock protein A
MTP03_19770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MTP03_19780	COG2137	regulation of response to DNA damage stimulus
MTP03_19800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP03_19810	COG0765	amino acid transport
MTP03_19820	COG0765	amino acid transport
MTP03_19830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP03_19840	COG1126	abc transporter atp-binding protein
MTP03_19850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MTP03_19870	COG1196	nuclear chromosome segregation
MTP03_19890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MTP03_19910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTP03_19940	COG1960	acyl-CoA dehydrogenase activity
MTP03_19950	COG1960	acyl-CoA dehydrogenase activity
MTP03_19990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTP03_20010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MTP03_20020	COG1643	Atp-dependent helicase
MTP03_20040	COG1643	Atp-dependent helicase
MTP03_20070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTP03_20080	COG1595	DNA-templated transcription, initiation
MTP03_20110	COG0450	alkyl hydroperoxide reductase
MTP03_20310	COG1321	iron dependent repressor
MTP03_20320	COG0123	including yeast histone deacetylase and acetoin utilization protein
MTP03_20330	COG0123	including yeast histone deacetylase and acetoin utilization protein
MTP03_20360	COG2890	protein-(glutamine-N5) methyltransferase activity
MTP03_20400	COG1061	Type III restriction enzyme res subunit
MTP03_20420	COG5006	permease, DMT superfamily
MTP03_20440	COG3590	peptidase
MTP03_20460	COG1960	acyl-CoA dehydrogenase activity
MTP03_20480	COG0183	Belongs to the thiolase family
MTP03_20490	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_20500	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_20520	COG1011	Hydrolase
MTP03_20570	COG1960	acyl-CoA dehydrogenase activity
MTP03_20580	COG1960	acyl-CoA dehydrogenase activity
MTP03_20600	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_20610	COG2267	carboxylic ester hydrolase activity
MTP03_20650	COG4770	biotin carboxylase activity
MTP03_20690	COG2197	response regulator
MTP03_20700	COG2197	response regulator
MTP03_20760	COG1940	carbohydrate kinase activity
MTP03_20820	COG0756	dUTP diphosphatase activity
MTP03_20860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MTP03_20910	COG3253	May function as heme-dependent peroxidase
MTP03_20970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MTP03_20980	COG1937	Protein conserved in bacteria
MTP03_21010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_21050	COG0346	lactoylglutathione lyase activity
MTP03_21150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MTP03_21180	COG1560	Kdo2-lipid A biosynthetic process
MTP03_21190	COG0438	transferase activity, transferring glycosyl groups
MTP03_21230	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MTP03_21260	COG1946	Acyl-CoA thioesterase
MTP03_21270	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MTP03_21320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MTP03_21330	COG0632	four-way junction helicase activity
MTP03_21340	COG2255	four-way junction helicase activity
MTP03_21350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MTP03_21410	COG2175	clavaminate synthase activity
MTP03_21420	COG3246	L-lysine catabolic process to acetate
MTP03_21480	COG0514	ATP-dependent DNA helicase (RecQ)
MTP03_21530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTP03_21540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTP03_21560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTP03_21590	COG0124	histidyl-tRNA synthetase
MTP03_21620	COG0640	Transcriptional regulator
MTP03_21640	COG0523	cobalamin synthesis protein
MTP03_21680	COG0277	FAD linked oxidase domain protein
MTP03_21730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MTP03_21790	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MTP03_21800	COG0444	Belongs to the ABC transporter superfamily
MTP03_21810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP03_21910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MTP03_21940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MTP03_21990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_22010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_22030	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_22050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP03_22060	COG1126	abc transporter atp-binding protein
MTP03_22070	COG0765	amino acid transport
MTP03_22080	COG2197	response regulator
MTP03_22140	COG4115	mRNA cleavage
MTP03_22180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_22190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_22290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MTP03_22300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MTP03_22310	COG0671	phosphoesterase, PA-phosphatase related
MTP03_22340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MTP03_22370	COG0431	NADPH-dependent FMN reductase
MTP03_22410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MTP03_22430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MTP03_22520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MTP03_22530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MTP03_22540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MTP03_22550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MTP03_22560	COG1953	Uracil, thiamine, allantoin
MTP03_22580	COG1301	dicarboxylic acid transport
MTP03_22590	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MTP03_22600	COG3257	ureidoglycine aminohydrolase activity
MTP03_22630	COG0402	S-adenosylhomocysteine deaminase activity
MTP03_22650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MTP03_22670	COG2252	PERMEase
MTP03_22710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MTP03_22730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MTP03_22740	COG0483	inositol monophosphate 1-phosphatase activity
MTP03_22750	COG0107	imidazoleglycerol-phosphate synthase activity
MTP03_22760	COG0107	imidazoleglycerol-phosphate synthase activity
MTP03_22770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MTP03_22790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MTP03_22810	COG0134	indole-3-glycerol-phosphate synthase activity
MTP03_22820	COG2971	BadF BadG BcrA BcrD
MTP03_22830	COG2814	Major facilitator Superfamily
MTP03_22840	COG2188	Transcriptional regulator
MTP03_22890	COG0159	tryptophan synthase activity
MTP03_22900	COG0488	(ABC) transporter
MTP03_22910	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_22940	COG1819	glycosyl
MTP03_22950	COG1309	transcriptional regulator
MTP03_22960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTP03_23010	COG3550	peptidyl-serine autophosphorylation
MTP03_23030	COG1396	sequence-specific DNA binding
MTP03_23140	COG0584	glycerophosphoryl diester phosphodiesterase
MTP03_23170	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MTP03_23200	COG0714	Associated with various cellular activities
MTP03_23270	COG1309	transcriptional regulator
MTP03_23280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTP03_23290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTP03_23300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTP03_23310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTP03_23330	COG0791	NLP P60 protein
MTP03_23330	COG3883	PFAM NLP P60 protein
MTP03_23340	COG0714	Associated with various cellular activities
MTP03_23360	COG2304	oxidoreductase activity
MTP03_23390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MTP03_23400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MTP03_23520	COG2267	carboxylic ester hydrolase activity
MTP03_23650	COG1233	COG1233 Phytoene dehydrogenase and related
MTP03_23660	COG2186	Transcriptional regulator
MTP03_23770	COG0028	Belongs to the TPP enzyme family
MTP03_23810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MTP03_23820	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_23850	COG3243	poly(R)-hydroxyalkanoic acid synthase
MTP03_23860	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MTP03_23880	COG0531	amino acid
MTP03_24000	COG3265	gluconokinase activity
MTP03_24010	COG3265	gluconokinase activity
MTP03_24140	COG1968	undecaprenyl-diphosphatase activity
MTP03_24150	COG1968	undecaprenyl-diphosphatase activity
MTP03_24160	COG0583	DNA-binding transcription factor activity
MTP03_24170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTP03_24220	COG3220	belongs to the UPF0276 family
MTP03_24260	COG0215	cysteine-tRNA ligase activity
MTP03_24300	COG1410	methionine synthase
MTP03_24300	COG0646	methionine synthase
MTP03_24310	COG0646	methionine synthase
MTP03_24310	COG1410	methionine synthase
MTP03_24320	COG0646	methionine synthase
MTP03_24320	COG1410	methionine synthase
MTP03_24340	COG0737	Belongs to the 5'-nucleotidase family
MTP03_24350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTP03_24370	COG0140	phosphoribosyl-ATP diphosphatase activity
MTP03_24380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MTP03_24420	COG0842	Transport permease protein
MTP03_24420	COG1131	(ABC) transporter
MTP03_24420	COG1716	ATPase activity
MTP03_24510	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MTP03_24540	COG0733	neurotransmitter:sodium symporter activity
MTP03_24610	COG2378	regulation of single-species biofilm formation
MTP03_24620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTP03_24680	COG0477	Major facilitator Superfamily
MTP03_24710	COG0300	oxidoreductase activity
MTP03_24770	COG3467	pyridoxamine 5'-phosphate
MTP03_24780	COG2814	Major facilitator Superfamily
MTP03_24790	COG1396	sequence-specific DNA binding
MTP03_24850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MTP03_24880	COG2826	transposase and inactivated derivatives, IS30 family
MTP03_24940	COG0463	Glycosyl transferase, family 2
MTP03_25000	COG1376	ErfK ybiS ycfS ynhG family protein
MTP03_25010	COG2072	flavoprotein involved in K transport
MTP03_25070	COG1454	alcohol dehydrogenase
MTP03_25130	COG2807	transmembrane transport
MTP03_25150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MTP03_25170	COG4974	Belongs to the 'phage' integrase family
MTP03_25240	COG0798	PFAM Bile acid sodium symporter
MTP03_25250	COG0640	Transcriptional regulator
MTP03_25280	COG1984	allophanate hydrolase subunit 2
MTP03_25290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MTP03_25340	COG2354	Protein conserved in bacteria
MTP03_25450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MTP03_25480	COG1063	alcohol dehydrogenase
MTP03_25530	COG2267	carboxylic ester hydrolase activity
MTP03_25570	COG2268	Band 7 protein
MTP03_25640	COG1074	ATP-dependent DNA helicase activity
MTP03_25650	COG1074	ATP-dependent DNA helicase activity
MTP03_25670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MTP03_25910	COG1253	flavin adenine dinucleotide binding
MTP03_25940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_25950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_25970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MTP03_26170	COG3795	YCII-related domain
MTP03_26210	COG1716	ATPase activity
MTP03_26240	COG0653	protein targeting
MTP03_26250	COG2234	aminopeptidase activity
MTP03_26260	COG0247	lactate metabolic process
MTP03_26260	COG0277	FAD linked oxidase domain protein
MTP03_26270	COG0247	lactate metabolic process
MTP03_26270	COG0277	FAD linked oxidase domain protein
MTP03_26280	COG0596	Alpha beta hydrolase
MTP03_26320	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTP03_26350	COG2365	Tyrosine phosphatase family
MTP03_26380	COG5650	phosphatidylinositol metabolic process
MTP03_26420	COG1160	GTP binding
MTP03_26430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MTP03_26480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MTP03_26520	COG0494	nUDIX hydrolase
MTP03_26600	COG0647	UMP catabolic process
MTP03_26630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MTP03_26640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MTP03_26650	COG2094	Belongs to the DNA glycosylase MPG family
MTP03_26660	COG2835	tetraacyldisaccharide 4'-kinase activity
MTP03_26690	COG1131	(ABC) transporter
MTP03_26720	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_26730	COG0165	Argininosuccinate lyase
MTP03_26740	COG0137	argininosuccinate synthase activity
MTP03_26750	COG1438	arginine binding
MTP03_26770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MTP03_26810	COG3284	Transcriptional regulator
MTP03_26830	COG3284	Transcriptional regulator
MTP03_26850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTP03_26850	COG0072	phenylalanine-tRNA ligase activity
MTP03_26860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MTP03_26910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MTP03_26980	COG3973	AAA domain
MTP03_27040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP03_27050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP03_27060	COG0237	dephospho-CoA kinase activity
MTP03_27060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTP03_27090	COG1070	Carbohydrate kinase
MTP03_27110	COG0246	Mannitol dehydrogenase
MTP03_27120	COG1063	alcohol dehydrogenase
MTP03_27170	COG0395	ABC-type sugar transport system, permease component
MTP03_27180	COG3842	ATPase activity
MTP03_27190	COG0539	negative regulation of cytoplasmic translation
MTP03_27210	COG4715	Zinc finger, swim domain protein
MTP03_27220	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MTP03_27250	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MTP03_27260	COG0714	Associated with various cellular activities
MTP03_27270	COG0714	Associated with various cellular activities
MTP03_27290	COG3831	ATPase activity
MTP03_27320	COG2226	methyltransferase
MTP03_27370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTP03_27530	COG4260	virion core protein, lumpy skin disease virus
MTP03_27540	COG3422	double-strand break repair
MTP03_27580	COG0477	Major facilitator Superfamily
MTP03_27600	COG0435	Glutathione S-transferase
MTP03_27630	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_27700	COG4303	Ethanolamine ammonia lyase large subunit
MTP03_27710	COG0531	amino acid
MTP03_27780	COG2124	cytochrome p450
MTP03_27780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MTP03_27880	COG1946	Acyl-CoA thioesterase
MTP03_27900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MTP03_27960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTP03_27980	COG1960	acyl-CoA dehydrogenase activity
MTP03_28030	COG2188	Transcriptional regulator
MTP03_28060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTP03_28160	COG1846	Transcriptional regulator
MTP03_28220	COG2151	metal-sulfur cluster biosynthetic enzyme
MTP03_28250	COG0396	ATPase activity
MTP03_28320	COG1131	(ABC) transporter
MTP03_28410	COG1902	pentaerythritol trinitrate reductase activity
MTP03_28410	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTP03_28420	COG0109	protoheme IX farnesyltransferase activity
MTP03_28440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MTP03_28530	COG1960	acyl-CoA dehydrogenase activity
MTP03_28540	COG1960	acyl-CoA dehydrogenase activity
MTP03_28570	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
MTP03_28580	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MTP03_28590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTP03_28600	COG0149	triose-phosphate isomerase activity
MTP03_28610	COG0126	phosphoglycerate kinase activity
MTP03_28620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTP03_28640	COG1481	regulation of sporulation
MTP03_28660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MTP03_28680	COG1660	Displays ATPase and GTPase activities
MTP03_28700	COG0405	Gamma-glutamyltransferase
MTP03_28720	COG3842	ATPase activity
MTP03_28770	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_28980	COG3104	oligopeptide transport
MTP03_29000	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_29040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTP03_29040	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTP03_29140	COG2826	transposase and inactivated derivatives, IS30 family
MTP03_29160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MTP03_29170	COG0242	peptide deformylase activity
MTP03_29180	COG0242	peptide deformylase activity
MTP03_29200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTP03_29290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MTP03_29310	COG1758	RNA polymerase activity
MTP03_29320	COG0194	GDP metabolic process
MTP03_29330	COG0284	orotidine-5'-phosphate decarboxylase activity
MTP03_29350	COG0505	Belongs to the CarA family
MTP03_29420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MTP03_29430	COG0006	proline dipeptidase activity
MTP03_29490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MTP03_29500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MTP03_29510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MTP03_29560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MTP03_29570	COG1193	negative regulation of DNA recombination
MTP03_29640	COG1090	epimerase
MTP03_29670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MTP03_29700	COG0252	asparaginase activity
MTP03_29710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTP03_29790	COG1024	Enoyl-CoA hydratase
MTP03_29800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MTP03_29860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MTP03_29870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MTP03_29880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MTP03_29900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MTP03_29910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTP03_29920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MTP03_29950	COG0768	penicillin binding
MTP03_29970	COG0275	rRNA processing
MTP03_29980	COG2001	Belongs to the MraZ family
MTP03_30050	COG0142	geranyltranstransferase activity
MTP03_30060	COG4607	ABC-type enterochelin transport system periplasmic component
MTP03_30090	COG4604	ABC transporter, ATP-binding protein
MTP03_30140	COG0515	serine threonine protein kinase
MTP03_30140	COG2815	serine threonine protein kinase
MTP03_30180	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MTP03_30210	COG1940	carbohydrate kinase activity
MTP03_30220	COG1940	carbohydrate kinase activity
MTP03_30280	COG1022	Amp-dependent synthetase and ligase
MTP03_30290	COG0438	transferase activity, transferring glycosyl groups
MTP03_30360	COG2301	Belongs to the HpcH HpaI aldolase family
MTP03_30370	COG0442	prolyl-tRNA aminoacylation
MTP03_30380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MTP03_30410	COG1845	cytochrome c oxidase, subunit III
MTP03_30480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MTP03_30500	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_30500	COG0604	alcohol dehydrogenase
MTP03_30500	COG3321	synthase
MTP03_30540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MTP03_30570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTP03_30600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MTP03_30660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTP03_30670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MTP03_30680	COG2233	PERMEase
MTP03_30720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MTP03_30730	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTP03_30760	COG0321	lipoyl(octanoyl) transferase activity
MTP03_30810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MTP03_30840	COG0174	glutamine synthetase
MTP03_30900	COG1136	(ABC) transporter
MTP03_30910	COG0515	serine threonine protein kinase
MTP03_30950	COG0545	Peptidyl-prolyl cis-trans isomerase
MTP03_30970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MTP03_30980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MTP03_30990	COG0174	glutamine synthetase
MTP03_31020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MTP03_31020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTP03_31030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MTP03_31040	COG0596	Alpha beta hydrolase
MTP03_31080	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
MTP03_31130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MTP03_31130	COG3323	Protein of unknown function (DUF1653)
MTP03_31180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MTP03_31240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MTP03_31270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTP03_31560	COG2226	methyltransferase
MTP03_31590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MTP03_31640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MTP03_31650	COG1278	Cold shock
MTP03_31670	COG0423	glycine-tRNA ligase activity
MTP03_31710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTP03_31740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTP03_31750	COG1846	Transcriptional regulator
MTP03_31770	COG1381	Involved in DNA repair and RecF pathway recombination
MTP03_31820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MTP03_31890	COG0484	heat shock protein binding
MTP03_31900	COG1420	regulation of RNA biosynthetic process
MTP03_31930	COG2968	Membrane
MTP03_31960	COG0175	sulfate reduction
MTP03_32010	COG0531	amino acid
MTP03_32010	COG1674	ftsk spoiiie
MTP03_32040	COG4552	Acetyltransferase involved in intracellular survival and related
MTP03_32070	COG3842	ATPase activity
MTP03_32080	COG4208	sulfate ABC transporter
MTP03_32140	COG3387	PFAM Glycoside hydrolase 15-related
MTP03_32180	COG0339	signal peptide processing
MTP03_32210	COG2070	2-Nitropropane dioxygenase
MTP03_32240	COG0481	GTPase activity
MTP03_32270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTP03_32280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTP03_32290	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_32360	COG1305	Transglutaminase-like
MTP03_32390	COG0268	Binds directly to 16S ribosomal RNA
MTP03_32420	COG1596	polysaccharide export
MTP03_32420	COG1555	photosystem II stabilization
MTP03_32450	COG2755	lipolytic protein G-D-S-L family
MTP03_32460	COG0406	alpha-ribazole phosphatase activity
MTP03_32480	COG0799	negative regulation of ribosome biogenesis
MTP03_32490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MTP03_32510	COG0542	response to heat
MTP03_32530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MTP03_32600	COG1960	acyl-CoA dehydrogenase activity
MTP03_32610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_32640	COG1024	Enoyl-CoA hydratase
MTP03_32660	COG1309	transcriptional regulator
MTP03_32680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MTP03_32700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MTP03_32740	COG1181	Belongs to the D-alanine--D-alanine ligase family
MTP03_32750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MTP03_32760	COG1920	GTP binding
MTP03_32770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MTP03_32790	COG0066	3-isopropylmalate dehydratase activity
MTP03_32800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MTP03_32830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTP03_32850	COG1846	Transcriptional regulator
MTP03_32920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MTP03_32930	COG1082	Xylose isomerase domain protein TIM barrel
MTP03_32940	COG0673	inositol 2-dehydrogenase activity
MTP03_32960	COG3962	Belongs to the TPP enzyme family
MTP03_32970	COG3718	enzyme involved in inositol metabolism
MTP03_33010	COG2188	Transcriptional regulator
MTP03_33040	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_33070	COG0673	inositol 2-dehydrogenase activity
MTP03_33080	COG1082	Xylose isomerase domain protein TIM barrel
MTP03_33100	COG0673	inositol 2-dehydrogenase activity
MTP03_33120	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTP03_33180	COG0673	inositol 2-dehydrogenase activity
MTP03_33190	COG2814	Major facilitator Superfamily
MTP03_33200	COG0589	response to stress
MTP03_33210	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP03_33230	COG2271	Major facilitator Superfamily
MTP03_33240	COG0473	3-isopropylmalate dehydrogenase activity
MTP03_33270	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_33330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MTP03_33340	COG0440	acetolactate synthase activity
MTP03_33350	COG0028	Belongs to the TPP enzyme family
MTP03_33380	COG0129	dihydroxy-acid dehydratase activity
MTP03_33420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTP03_33440	COG0205	6-phosphofructokinase activity
MTP03_33450	COG2197	response regulator
MTP03_33460	COG4585	Histidine kinase
MTP03_33530	COG1959	2 iron, 2 sulfur cluster binding
MTP03_33540	COG0154	amidase activity
MTP03_33550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MTP03_33570	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_33630	COG2072	flavoprotein involved in K transport
MTP03_33640	COG2072	flavoprotein involved in K transport
MTP03_33650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MTP03_33720	COG1024	Enoyl-CoA hydratase
MTP03_33740	COG1607	acyl-coa hydrolase
MTP03_33840	COG2986	histidine ammonia-lyase
MTP03_33870	COG1228	amidohydrolase
MTP03_33880	COG1228	amidohydrolase
MTP03_33890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MTP03_33900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MTP03_33930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MTP03_33950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MTP03_34140	COG2132	Multicopper oxidase
MTP03_34150	COG4585	Histidine kinase
MTP03_34160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MTP03_34180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MTP03_34250	COG0110	maltose O-acetyltransferase activity
MTP03_34290	COG0024	Methionine aminopeptidase
MTP03_34330	COG0436	Aminotransferase
MTP03_34350	COG2226	methyltransferase
MTP03_34380	COG1119	ATPase activity
MTP03_34390	COG1523	belongs to the glycosyl hydrolase 13 family
MTP03_34410	COG0560	Phosphoserine phosphatase
MTP03_34410	COG3830	Belongs to the UPF0237 family
MTP03_34470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTP03_34500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MTP03_34540	COG2146	nitrite reductase [NAD(P)H] activity
MTP03_34590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTP03_34640	COG0300	oxidoreductase activity
MTP03_34680	COG0523	cobalamin synthesis protein
MTP03_34700	COG1054	Belongs to the UPF0176 family
MTP03_34730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MTP03_34750	COG0640	Transcriptional regulator
MTP03_34860	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MTP03_34900	COG1309	transcriptional regulator
MTP03_34920	COG1024	Enoyl-CoA hydratase
MTP03_34930	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_34950	COG2030	dehydratase
MTP03_34990	COG2801	Transposase and inactivated derivatives
MTP03_35030	COG0033	Phosphoglucomutase
MTP03_35040	COG2610	gluconate transmembrane transporter activity
MTP03_35050	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MTP03_35120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MTP03_35170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MTP03_35180	COG2177	Part of the ABC transporter FtsEX involved in
MTP03_35190	COG2884	Cell division ATP-binding protein ftsE
MTP03_35210	COG0668	transmembrane transport
MTP03_35220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MTP03_35250	COG0483	inositol monophosphate 1-phosphatase activity
MTP03_35260	COG1960	acyl-CoA dehydrogenase activity
MTP03_35270	COG1960	acyl-CoA dehydrogenase activity
MTP03_35280	COG1960	acyl-CoA dehydrogenase activity
MTP03_35290	COG1388	LysM domain
MTP03_35300	COG2814	Major facilitator Superfamily
MTP03_35330	COG0730	response to heat
MTP03_35380	COG1615	UPF0182 protein
MTP03_35400	COG3480	Lon protease (S16) C-terminal proteolytic domain
MTP03_35460	COG1960	acyl-CoA dehydrogenase activity
MTP03_35560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTP03_35590	COG0210	DNA helicase
MTP03_35600	COG0210	DNA helicase
MTP03_35620	COG0596	Alpha beta hydrolase
MTP03_35710	COG0596	Alpha beta hydrolase
MTP03_35710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTP03_35720	COG1309	transcriptional regulator
MTP03_35740	COG0513	Belongs to the DEAD box helicase family
MTP03_35790	COG1192	Involved in chromosome partitioning
MTP03_35800	COG0406	alpha-ribazole phosphatase activity
MTP03_35880	COG1595	DNA-templated transcription, initiation
MTP03_35900	COG2337	Toxic component of a toxin-antitoxin (TA) module
MTP03_35920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MTP03_35930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTP03_35940	COG4221	oxidoreductase activity
MTP03_35970	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_36000	COG2135	peptidase activity
MTP03_36030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MTP03_36050	COG1162	GTPase activity
MTP03_36060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTP03_36120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTP03_36130	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MTP03_36140	COG1113	amino acid transport
MTP03_36280	COG0653	protein targeting
MTP03_36290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MTP03_36330	COG5401	PFAM Sporulation and spore germination
MTP03_36350	COG5401	PFAM Sporulation and spore germination
MTP03_36360	COG5002	protein histidine kinase activity
MTP03_36370	COG0745	RESPONSE REGULATOR receiver
MTP03_36420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MTP03_36430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTP03_36440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTP03_36450	COG5662	AntiSigma factor
MTP03_36460	COG1595	DNA-templated transcription, initiation
MTP03_36470	COG4122	O-methyltransferase activity
MTP03_36490	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
MTP03_36500	COG2755	lipolytic protein G-D-S-L family
MTP03_36560	COG1316	TRANSCRIPTIONal
MTP03_36650	COG2205	protein histidine kinase activity
MTP03_36660	COG0745	RESPONSE REGULATOR receiver
MTP03_36700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_36710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_36730	COG0424	maF-like protein
MTP03_36770	COG2755	lipolytic protein G-D-S-L family
MTP03_36780	COG0477	Major facilitator Superfamily
MTP03_36840	COG4770	biotin carboxylase activity
MTP03_36880	COG1201	RNA secondary structure unwinding
MTP03_36890	COG1201	RNA secondary structure unwinding
MTP03_36900	COG1201	RNA secondary structure unwinding
MTP03_36920	COG3360	Dodecin
MTP03_36930	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_36980	COG0477	Major facilitator Superfamily
MTP03_37000	COG2197	response regulator
MTP03_37030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MTP03_37040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_37050	COG0148	phosphopyruvate hydratase activity
MTP03_37060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTP03_37080	COG2390	Transcriptional regulator
MTP03_37090	COG0205	6-phosphofructokinase activity
MTP03_37120	COG1349	DNA-binding transcription factor activity
MTP03_37170	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_37190	COG2271	Major facilitator Superfamily
MTP03_37210	COG2175	clavaminate synthase activity
MTP03_37280	COG1473	amidohydrolase
MTP03_37280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MTP03_37330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTP03_37400	COG2197	response regulator
MTP03_37410	COG4585	Histidine kinase
MTP03_37460	COG2009	succinate dehydrogenase
MTP03_37490	COG1053	succinate dehydrogenase
MTP03_37500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MTP03_37610	COG1686	Belongs to the peptidase S11 family
MTP03_37640	COG0180	Tryptophanyl-tRNA synthetase
MTP03_37650	COG0708	Exodeoxyribonuclease III
MTP03_37680	COG2814	Major facilitator Superfamily
MTP03_37720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MTP03_37740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MTP03_37760	COG1396	sequence-specific DNA binding
MTP03_37760	COG3800	Transcriptional regulator
MTP03_37770	COG2079	MmgE PrpD family protein
MTP03_37780	COG2079	MmgE PrpD family protein
MTP03_37790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MTP03_37890	COG1872	DUF167
MTP03_37950	COG0587	DNA-directed DNA polymerase activity
MTP03_37960	COG1742	UPF0060 membrane protein
MTP03_38140	COG0833	amino acid
MTP03_38160	COG0515	serine threonine protein kinase
MTP03_38170	COG2197	response regulator
MTP03_38230	COG0702	epimerase
MTP03_38240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MTP03_38240	COG0519	Catalyzes the synthesis of GMP from XMP
MTP03_38280	COG0516	GMP reductase activity
MTP03_38350	COG0459	protein refolding
MTP03_38360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MTP03_38430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MTP03_38440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MTP03_38450	COG0456	acetyltransferase
MTP03_38500	COG2154	pterin-4-alpha-carbinolamine dehydratase
MTP03_38530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTP03_38600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTP03_38620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MTP03_38680	COG1674	ftsk spoiiie
MTP03_38700	COG1404	Belongs to the peptidase S8 family
MTP03_38840	COG0101	tRNA pseudouridine synthase activity
MTP03_38850	COG0101	tRNA pseudouridine synthase activity
MTP03_38880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_38910	COG0203	ribosomal protein L17
MTP03_38920	COG0202	RNA polymerase activity
MTP03_38930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MTP03_38940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MTP03_38950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MTP03_38970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MTP03_38980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MTP03_38990	COG2873	o-acetylhomoserine
MTP03_39010	COG0789	Transcriptional regulator
MTP03_39030	COG0563	adenylate kinase activity
MTP03_39080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MTP03_39090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MTP03_39100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MTP03_39170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MTP03_39180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MTP03_39190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MTP03_39270	COG0513	Belongs to the DEAD box helicase family
MTP03_39310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MTP03_39320	COG0255	Belongs to the universal ribosomal protein uL29 family
MTP03_39330	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MTP03_39340	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MTP03_39360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MTP03_39370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MTP03_39380	COG0089	rRNA binding
MTP03_39390	COG0088	Forms part of the polypeptide exit tunnel
MTP03_39400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MTP03_39410	COG0051	transcription antitermination factor activity, RNA binding
MTP03_39460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_39470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_39490	COG2072	flavoprotein involved in K transport
MTP03_39500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MTP03_39570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MTP03_39580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MTP03_39590	COG0049	tRNA binding
MTP03_39600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MTP03_39640	COG1131	(ABC) transporter
MTP03_39690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MTP03_39740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MTP03_39750	COG1595	DNA-templated transcription, initiation
MTP03_39770	COG0640	Transcriptional regulator
MTP03_39830	COG3842	ATPase activity
MTP03_39840	COG1653	transport
MTP03_39910	COG2197	response regulator
MTP03_39960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MTP03_40000	COG0456	acetyltransferase
MTP03_40010	COG0456	acetyltransferase
MTP03_40020	COG0745	RESPONSE REGULATOR receiver
MTP03_40040	COG2897	thiosulfate sulfurtransferase activity
MTP03_40060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTP03_40080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTP03_40110	COG4044	May play a role in the intracellular transport of hydrophobic ligands
MTP03_40130	COG1309	transcriptional regulator
MTP03_40140	COG1131	(ABC) transporter
MTP03_40150	COG1131	(ABC) transporter
MTP03_40210	COG4988	ABC transporter
MTP03_40220	COG4988	ABC transporter
MTP03_40230	COG1294	oxidase, subunit
MTP03_40240	COG1271	oxidase subunit
MTP03_40250	COG1271	oxidase subunit
MTP03_40260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTP03_40270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MTP03_40300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MTP03_40410	COG1113	amino acid transport
MTP03_40420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTP03_40500	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_40520	COG1301	dicarboxylic acid transport
MTP03_40540	COG4565	transcriptional regulatory protein
MTP03_40560	COG3938	Belongs to the proline racemase family
MTP03_40570	COG0604	alcohol dehydrogenase
MTP03_40610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTP03_40620	COG1113	amino acid transport
MTP03_40630	COG2084	Dehydrogenase
MTP03_40650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MTP03_40670	COG0477	Major facilitator Superfamily
MTP03_40680	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_40690	COG1063	alcohol dehydrogenase
MTP03_40700	COG1362	aminopeptidase activity
MTP03_40710	COG0047	phosphoribosylformylglycinamidine synthase activity
MTP03_40720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTP03_40760	COG0386	Belongs to the glutathione peroxidase family
MTP03_40780	COG0477	Major facilitator Superfamily
MTP03_40800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MTP03_40820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MTP03_40860	COG2205	protein histidine kinase activity
MTP03_40870	COG0745	RESPONSE REGULATOR receiver
MTP03_40900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MTP03_40930	COG1024	Enoyl-CoA hydratase
MTP03_41010	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MTP03_41030	COG1305	Transglutaminase-like
MTP03_41050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MTP03_41130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MTP03_41140	COG0788	formyltetrahydrofolate deformylase activity
MTP03_41210	COG2733	membrane
MTP03_41220	COG2326	polyphosphate kinase activity
MTP03_41240	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_41250	COG0583	DNA-binding transcription factor activity
MTP03_41260	COG2226	methyltransferase
MTP03_41280	COG2224	Isocitrate lyase
MTP03_41310	COG5285	phytanoyl-CoA dioxygenase
MTP03_41350	COG1505	serine-type exopeptidase activity
MTP03_41360	COG1505	serine-type exopeptidase activity
MTP03_41420	COG2326	polyphosphate kinase activity
MTP03_41440	COG1132	(ABC) transporter
MTP03_41460	COG3433	isochorismatase activity
MTP03_41460	COG1535	isochorismatase
MTP03_41470	COG1021	2,3-dihydroxybenzoate-AMP ligase
MTP03_41480	COG1021	2,3-dihydroxybenzoate-AMP ligase
MTP03_41580	COG1535	isochorismatase
MTP03_41580	COG3433	isochorismatase activity
MTP03_41600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MTP03_41620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTP03_41640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_41710	COG0326	Molecular chaperone. Has ATPase activity
MTP03_41810	COG0688	phosphatidylethanolamine metabolic process
MTP03_41830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP03_41840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTP03_41860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTP03_41860	COG2111	Na H antiporter
MTP03_41870	COG2111	Na H antiporter
MTP03_41870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTP03_41880	COG1006	Multisubunit Na H antiporter MnhC subunit
MTP03_41890	COG0651	ATP synthesis coupled electron transport
MTP03_41910	COG1320	monovalent cation:proton antiporter activity
MTP03_41920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTP03_41970	COG1120	ATPase activity
MTP03_41980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_41990	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MTP03_42070	COG4555	ABC transporter
MTP03_42090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MTP03_42110	COG0351	phosphomethylpyrimidine kinase
MTP03_42130	COG0351	phosphomethylpyrimidine kinase
MTP03_42180	COG2197	response regulator
MTP03_42190	COG0477	Major facilitator Superfamily
MTP03_42200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MTP03_42220	COG2022	thiamine diphosphate biosynthetic process
MTP03_42240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP03_42260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTP03_42270	COG0352	thiamine-phosphate diphosphorylase activity
MTP03_42300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTP03_42330	COG1120	ATPase activity
MTP03_42340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_42350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_42360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTP03_42390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MTP03_42420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_42450	COG1132	(ABC) transporter
MTP03_42460	COG1132	(ABC) transporter
MTP03_42460	COG2375	cellular response to nickel ion
MTP03_42470	COG1132	(ABC) transporter
MTP03_42470	COG2375	cellular response to nickel ion
MTP03_42480	COG1132	(ABC) transporter
MTP03_42540	COG0657	acetylesterase activity
MTP03_42620	COG4941	Belongs to the sigma-70 factor family
MTP03_42640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MTP03_42650	COG1088	dTDP-glucose 4,6-dehydratase activity
MTP03_42660	COG1309	transcriptional regulator
MTP03_42670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTP03_42680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTP03_42740	COG1960	acyl-CoA dehydrogenase activity
MTP03_42750	COG3971	2-oxopent-4-enoate hydratase activity
MTP03_42810	COG1414	Transcriptional regulator
MTP03_42850	COG1960	acyl-CoA dehydrogenase activity
MTP03_42860	COG1960	acyl-CoA dehydrogenase activity
MTP03_42870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MTP03_42890	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_42900	COG1793	dna ligase
MTP03_42910	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_42920	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_42930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTP03_42960	COG2070	2-Nitropropane dioxygenase
MTP03_42980	COG2826	transposase and inactivated derivatives, IS30 family
MTP03_42990	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_43000	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_43050	COG2124	cytochrome p450
MTP03_43060	COG0183	Belongs to the thiolase family
MTP03_43070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTP03_43080	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_43100	COG1024	Enoyl-CoA hydratase
MTP03_43140	COG0183	Belongs to the thiolase family
MTP03_43150	COG1309	transcriptional regulator
MTP03_43160	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_43170	COG1960	acyl-CoA dehydrogenase activity
MTP03_43180	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_43190	COG1024	Enoyl-CoA hydratase
MTP03_43200	COG1024	Enoyl-CoA hydratase
MTP03_43210	COG1960	acyl-CoA dehydrogenase activity
MTP03_43220	COG1960	acyl-CoA dehydrogenase activity
MTP03_43240	COG1960	acyl-CoA dehydrogenase activity
MTP03_43270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTP03_43280	COG0346	lactoylglutathione lyase activity
MTP03_43290	COG2267	carboxylic ester hydrolase activity
MTP03_43300	COG1960	acyl-CoA dehydrogenase activity
MTP03_43310	COG1053	succinate dehydrogenase
MTP03_43330	COG1053	succinate dehydrogenase
MTP03_43380	COG2030	dehydratase
MTP03_43440	COG1960	acyl-CoA dehydrogenase activity
MTP03_43450	COG2030	dehydratase
MTP03_43630	COG3328	transposase activity
MTP03_43640	COG3328	transposase activity
MTP03_43660	COG2801	Transposase and inactivated derivatives
MTP03_43670	COG0243	molybdopterin cofactor binding
MTP03_43690	COG2508	Transcriptional regulator
MTP03_43700	COG2072	flavoprotein involved in K transport
MTP03_43730	COG0470	DNA polymerase III
MTP03_43750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTP03_43750	COG1754	DNA topoisomerase type I activity
MTP03_43760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTP03_43760	COG1754	DNA topoisomerase type I activity
MTP03_43780	COG1278	Cold shock
MTP03_43790	COG1205	dead DEAH box helicase
MTP03_43790	COG1111	helicase
MTP03_43800	COG1111	helicase
MTP03_43800	COG1205	dead DEAH box helicase
MTP03_43910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTP03_43920	COG0601	transmembrane transport
MTP03_43950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTP03_43980	COG1131	(ABC) transporter
MTP03_44010	COG0477	Major facilitator Superfamily
MTP03_44020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MTP03_44040	COG2226	methyltransferase
MTP03_44040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTP03_44040	COG0596	Alpha beta hydrolase
MTP03_44070	COG0494	nUDIX hydrolase
MTP03_44120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTP03_44160	COG0003	Pfam Anion-transporting ATPase
MTP03_44190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MTP03_44200	COG1960	acyl-CoA dehydrogenase activity
MTP03_44250	COG1024	Enoyl-CoA hydratase
MTP03_44290	COG2814	Major facilitator Superfamily
MTP03_44310	COG2801	Transposase and inactivated derivatives
MTP03_44320	COG0477	Major facilitator Superfamily
MTP03_44360	COG2124	cytochrome p450
MTP03_44420	COG1021	2,3-dihydroxybenzoate-AMP ligase
MTP03_44440	COG3473	Maleate cis-trans isomerase
MTP03_44490	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_44500	COG1408	metallophosphoesterase
MTP03_44530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MTP03_44540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MTP03_44550	COG1764	response to oxidative stress
MTP03_44600	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_44610	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_44630	COG0583	DNA-binding transcription factor activity
MTP03_44660	COG0135	phosphoribosylanthranilate isomerase activity
MTP03_44700	COG1309	transcriptional regulator
MTP03_44750	COG3473	Maleate cis-trans isomerase
MTP03_44760	COG1309	transcriptional regulator
MTP03_44770	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_44780	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_44810	COG1021	2,3-dihydroxybenzoate-AMP ligase
MTP03_44820	COG2814	Major facilitator Superfamily
MTP03_44830	COG2814	Major facilitator Superfamily
MTP03_44900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTP03_44930	COG1959	2 iron, 2 sulfur cluster binding
MTP03_44940	COG0300	oxidoreductase activity
MTP03_44990	COG2807	transmembrane transport
MTP03_45000	COG1802	Transcriptional regulator
MTP03_45010	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTP03_45060	COG0697	spore germination
MTP03_45150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTP03_45200	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTP03_45210	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTP03_45220	COG0564	pseudouridine synthase activity
MTP03_45260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MTP03_45340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTP03_45410	COG0640	Transcriptional regulator
MTP03_45440	COG1793	dna ligase
MTP03_45450	COG2318	DinB family
MTP03_45470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MTP03_45480	COG4977	sequence-specific DNA binding
MTP03_45490	COG0343	queuine tRNA-ribosyltransferase activity
MTP03_45570	COG0287	Prephenate dehydrogenase
MTP03_45670	COG0739	heme binding
MTP03_45780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MTP03_45860	COG2030	dehydratase
MTP03_45870	COG0477	Major facilitator Superfamily
MTP03_45890	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_45900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTP03_45910	COG1024	Enoyl-CoA hydratase
MTP03_45960	COG1960	acyl-CoA dehydrogenase activity
MTP03_45970	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_45990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MTP03_46010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MTP03_46020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MTP03_46090	COG3321	synthase
MTP03_46090	COG0604	alcohol dehydrogenase
MTP03_46090	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_46170	COG1216	Glycosyl transferase, family 2
MTP03_46180	COG0318	PFAM AMP-dependent synthetase and ligase
MTP03_46190	COG2814	Major facilitator Superfamily
MTP03_46250	COG1476	TRANSCRIPTIONal
MTP03_46270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MTP03_46280	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_46290	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_46300	COG0006	proline dipeptidase activity
MTP03_46310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTP03_46320	COG1473	amidohydrolase
MTP03_46350	COG1028	Short-chain dehydrogenase reductase Sdr
MTP03_46370	COG4221	oxidoreductase activity
MTP03_46380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTP03_46410	COG1122	ATPase activity
MTP03_46420	COG1268	BioY protein
MTP03_46440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MTP03_46510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MTP03_46550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTP03_46600	COG1174	glycine betaine transport
MTP03_46630	COG3973	AAA domain
MTP03_46710	COG1376	ErfK ybiS ycfS ynhG family protein
MTP03_46720	COG0659	secondary active sulfate transmembrane transporter activity
MTP03_46730	COG2205	protein histidine kinase activity
MTP03_46740	COG0745	RESPONSE REGULATOR receiver
MTP03_46820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTP03_46830	COG0785	Cytochrome C biogenesis protein
MTP03_46910	COG0758	DNA mediated transformation
MTP03_46980	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MTP03_47000	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MTP03_47130	COG0359	binds to the 23S rRNA
MTP03_47160	COG0360	Binds together with S18 to 16S ribosomal RNA
MTP03_47180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MTP03_47330	COG0183	Belongs to the thiolase family
MTP03_47340	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP03_47340	COG1024	Enoyl-CoA hydratase
MTP03_47350	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTP03_47350	COG1024	Enoyl-CoA hydratase
MTP03_47360	COG3547	Transposase (IS116 IS110 IS902 family)
MTP03_47370	COG1024	Enoyl-CoA hydratase
MTP03_47440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTP03_47470	COG1260	myo-inositol-1-phosphate synthase
MTP03_47610	COG1358	cellular component organization or biogenesis
MTP03_47640	COG1297	OPT oligopeptide transporter protein
MTP03_47680	COG2814	Major facilitator Superfamily
MTP03_47690	COG4221	oxidoreductase activity
MTP03_47700	COG4122	O-methyltransferase activity
MTP03_47740	COG0495	leucyl-tRNA aminoacylation
MTP03_47750	COG0495	leucyl-tRNA aminoacylation
MTP03_47800	COG1678	Uncharacterized ACR, COG1678
MTP03_47840	COG0617	tRNA 3'-terminal CCA addition
MTP03_47920	COG0519	Catalyzes the synthesis of GMP from XMP
MTP03_47930	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_47940	COG1012	belongs to the aldehyde dehydrogenase family
MTP03_48000	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTP03_48000	COG3409	Peptidoglycan-binding domain 1 protein
MTP03_48030	COG0357	Ribosomal RNA small subunit methyltransferase G
MTP03_48040	COG0357	Ribosomal RNA small subunit methyltransferase G
MTP03_48060	COG0706	membrane insertase activity
MTP03_48070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MTP03_48080	COG0594	ribonuclease P activity