locus-tag	class	description
J0J80_00010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J0J80_00015	COG2255	four-way junction helicase activity
J0J80_00025	COG0632	four-way junction helicase activity
J0J80_00030	COG2116	formate transmembrane transporter activity
J0J80_00050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_00055	COG1621	beta-fructofuranosidase activity
J0J80_00060	COG1263	PTS System
J0J80_00060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_00065	COG1609	Transcriptional regulator
J0J80_00075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J0J80_00080	COG0826	peptidase U32
J0J80_00085	COG0653	protein targeting
J0J80_00115	COG4989	oxidoreductase activity
J0J80_00145	COG0733	neurotransmitter:sodium symporter activity
J0J80_00155	COG3621	Patatin-like phospholipase
J0J80_00195	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
J0J80_00205	COG0446	pyridine nucleotide-disulphide oxidoreductase
J0J80_00355	COG3328	transposase activity
J0J80_00360	COG2826	transposase and inactivated derivatives, IS30 family
J0J80_00575	COG0671	phosphoesterase, PA-phosphatase related
J0J80_00585	COG3328	transposase activity
J0J80_00600	COG0116	Belongs to the methyltransferase superfamily
J0J80_00625	COG4677	pectinesterase activity
J0J80_00640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0J80_00650	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J0J80_00655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J0J80_00665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J0J80_00670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0J80_00670	COG0784	Response regulator, receiver
J0J80_00670	COG2198	Histidine kinase
J0J80_00670	COG2205	protein histidine kinase activity
J0J80_00675	COG1994	Peptidase M50
J0J80_00700	COG0367	asparagine synthase
J0J80_00710	COG2003	Belongs to the UPF0758 family
J0J80_00720	COG0285	dihydrofolate synthase activity
J0J80_00745	COG1363	Peptidase, m42
J0J80_00750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J0J80_00755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J0J80_00760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J0J80_00770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J0J80_00775	COG1484	DNA-dependent DNA replication
J0J80_00780	COG3611	Membrane attachment protein
J0J80_00790	COG0237	dephospho-CoA kinase activity
J0J80_00795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J0J80_00810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0J80_00810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J0J80_00815	COG1408	metallophosphoesterase
J0J80_00825	COG2084	Dehydrogenase
J0J80_00845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J0J80_00855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_00855	COG2190	(PTS) system
J0J80_00855	COG1263	PTS System
J0J80_00860	COG1263	PTS System
J0J80_00860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_00860	COG2190	(PTS) system
J0J80_00865	COG0142	geranyltranstransferase activity
J0J80_00870	COG1252	NADH dehydrogenase
J0J80_00900	COG1051	belongs to the nudix hydrolase family
J0J80_00910	COG0205	6-phosphofructokinase activity
J0J80_00915	COG0587	DNA-directed DNA polymerase activity
J0J80_00920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0J80_00925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J0J80_00930	COG0827	DNA restriction-modification system
J0J80_00935	COG3874	Sporulation protein YtfJ
J0J80_00945	COG0367	asparagine synthase
J0J80_00955	COG2860	membrane
J0J80_00960	COG0488	(ABC) transporter
J0J80_00965	COG1362	aminopeptidase activity
J0J80_01040	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_01040	COG1388	LysM domain
J0J80_01045	COG1045	serine acetyltransferase
J0J80_01065	COG1098	S1 RNA binding domain
J0J80_01070	COG0492	ferredoxin-NADP+ reductase activity
J0J80_01075	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J0J80_01080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J0J80_01090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J0J80_01100	COG0561	phosphatase activity
J0J80_01105	COG0647	UMP catabolic process
J0J80_01110	COG4470	Protein conserved in bacteria
J0J80_01125	COG0534	Mate efflux family protein
J0J80_01130	COG1609	Transcriptional regulator
J0J80_01135	COG3842	ATPase activity
J0J80_01140	COG2508	Transcriptional regulator
J0J80_01150	COG0564	pseudouridine synthase activity
J0J80_01155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J0J80_01160	COG2357	RelA SpoT domain protein
J0J80_01180	COG1393	Belongs to the ArsC family
J0J80_01185	COG3328	transposase activity
J0J80_01195	COG4608	Belongs to the ABC transporter superfamily
J0J80_01200	COG0444	Belongs to the ABC transporter superfamily
J0J80_01205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_01210	COG0601	transmembrane transport
J0J80_01215	COG4166	transmembrane transport
J0J80_01230	COG1132	(ABC) transporter
J0J80_01235	COG1132	(ABC) transporter
J0J80_01245	COG0542	response to heat
J0J80_01250	COG0561	phosphatase activity
J0J80_01260	COG0495	leucyl-tRNA aminoacylation
J0J80_01265	COG1242	4 iron, 4 sulfur cluster binding
J0J80_01270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J0J80_01295	COG0589	response to stress
J0J80_01300	COG0149	triose-phosphate isomerase activity
J0J80_01305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J0J80_01310	COG4191	Histidine kinase
J0J80_01310	COG0784	Response regulator, receiver
J0J80_01330	COG2267	carboxylic ester hydrolase activity
J0J80_01350	COG2814	Major facilitator Superfamily
J0J80_01355	COG1120	ATPase activity
J0J80_01360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_01365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_01390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J0J80_01395	COG1757	Na H antiporter
J0J80_01420	COG0531	amino acid
J0J80_01430	COG0697	spore germination
J0J80_01450	COG0463	Glycosyl transferase, family 2
J0J80_01485	COG3328	transposase activity
J0J80_01495	COG1408	metallophosphoesterase
J0J80_01515	COG0463	Glycosyl transferase, family 2
J0J80_01535	COG1216	Glycosyl transferase, family 2
J0J80_01540	COG1216	Glycosyl transferase, family 2
J0J80_01545	COG1216	Glycosyl transferase, family 2
J0J80_01550	COG0438	transferase activity, transferring glycosyl groups
J0J80_01555	COG1215	transferase activity, transferring glycosyl groups
J0J80_01565	COG1216	Glycosyl transferase, family 2
J0J80_01575	COG1216	Glycosyl transferase, family 2
J0J80_01580	COG1442	glycosyl transferase family 8
J0J80_01580	COG1216	Glycosyl transferase, family 2
J0J80_01585	COG0438	transferase activity, transferring glycosyl groups
J0J80_01595	COG0438	transferase activity, transferring glycosyl groups
J0J80_01600	COG0438	transferase activity, transferring glycosyl groups
J0J80_01605	COG0489	protein tyrosine kinase activity
J0J80_01615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J0J80_01620	COG0110	maltose O-acetyltransferase activity
J0J80_01625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_01655	COG1132	(ABC) transporter
J0J80_01660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J0J80_01705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0J80_01710	COG1316	TRANSCRIPTIONal
J0J80_01760	COG3475	LICD family
J0J80_01785	COG1216	Glycosyl transferase, family 2
J0J80_01815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J0J80_01820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_01825	COG0489	protein tyrosine kinase activity
J0J80_01845	COG4750	Nucleotidyl transferase
J0J80_01850	COG0697	spore germination
J0J80_01860	COG0463	Glycosyl transferase, family 2
J0J80_01880	COG2089	acid synthase
J0J80_01885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J0J80_01905	COG3475	LICD family
J0J80_01910	COG1216	Glycosyl transferase, family 2
J0J80_01920	COG1216	Glycosyl transferase, family 2
J0J80_01925	COG5263	repeat protein
J0J80_01925	COG4193	domain, Protein
J0J80_01955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J0J80_01965	COG1316	TRANSCRIPTIONal
J0J80_01980	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_02015	COG0602	queuosine metabolic process
J0J80_02025	COG1328	CTP reductase activity
J0J80_02030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J0J80_02030	COG1328	CTP reductase activity
J0J80_02045	COG3344	reverse transcriptase
J0J80_02070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J0J80_02075	COG1121	(ABC) transporter
J0J80_02080	COG0803	Belongs to the bacterial solute-binding protein 9 family
J0J80_02100	COG1737	Transcriptional regulator
J0J80_02105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_02125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J0J80_02130	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_02165	COG1874	Beta-galactosidase
J0J80_02170	COG3328	transposase activity
J0J80_02185	COG5632	N-Acetylmuramoyl-L-alanine amidase
J0J80_02185	COG3409	Peptidoglycan-binding domain 1 protein
J0J80_02190	COG1253	flavin adenine dinucleotide binding
J0J80_02205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J0J80_02230	COG0402	S-adenosylhomocysteine deaminase activity
J0J80_02235	COG2985	domain, Protein
J0J80_02240	COG0584	glycerophosphoryl diester phosphodiesterase
J0J80_02245	COG1959	2 iron, 2 sulfur cluster binding
J0J80_02270	COG1307	EDD domain protein, DegV family
J0J80_02285	COG1126	abc transporter atp-binding protein
J0J80_02290	COG4215	(ABC) transporter
J0J80_02295	COG0765	amino acid transport
J0J80_02300	COG1131	(ABC) transporter
J0J80_02315	COG2205	protein histidine kinase activity
J0J80_02320	COG0745	RESPONSE REGULATOR receiver
J0J80_02350	COG0488	(ABC) transporter
J0J80_02375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_02385	COG2226	methyltransferase
J0J80_02405	COG1760	l-serine dehydratase
J0J80_02410	COG0556	nucleotide-excision repair
J0J80_02415	COG3409	Peptidoglycan-binding domain 1 protein
J0J80_02415	COG0793	Belongs to the peptidase S41A family
J0J80_02425	COG2177	Part of the ABC transporter FtsEX involved in
J0J80_02430	COG2884	Cell division ATP-binding protein ftsE
J0J80_02435	COG1854	S-ribosylhomocysteine lyase activity
J0J80_02440	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J0J80_02465	COG1105	Belongs to the carbohydrate kinase PfkB family
J0J80_02490	COG1739	Uncharacterized protein family UPF0029
J0J80_02495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J0J80_02500	COG1077	Cell shape determining protein MreB Mrl
J0J80_02510	COG2385	sporulation resulting in formation of a cellular spore
J0J80_02520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J0J80_02525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J0J80_02535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J0J80_02545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J0J80_02550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J0J80_02570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J0J80_02575	COG0698	ribose 5-phosphate isomerase
J0J80_02590	COG0009	L-threonylcarbamoyladenylate synthase
J0J80_02595	COG2890	protein-(glutamine-N5) methyltransferase activity
J0J80_02600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J0J80_02605	COG0305	Participates in initiation and elongation during chromosome replication
J0J80_02610	COG0359	binds to the 23S rRNA
J0J80_02615	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J0J80_02630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J0J80_02635	COG0629	single-stranded DNA binding
J0J80_02640	COG0360	Binds together with S18 to 16S ribosomal RNA
J0J80_02645	COG0012	GTP binding
J0J80_02655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J0J80_02660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0J80_02665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J0J80_02670	COG0084	hydrolase, TatD family'
J0J80_02675	COG4608	Belongs to the ABC transporter superfamily
J0J80_02680	COG0444	Belongs to the ABC transporter superfamily
J0J80_02685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_02690	COG0601	transmembrane transport
J0J80_02695	COG4166	transmembrane transport
J0J80_02705	COG3328	transposase activity
J0J80_02735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J0J80_02745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_02750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J0J80_02755	COG1774	PSP1 C-terminal conserved region
J0J80_02760	COG0470	DNA polymerase III
J0J80_02765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J0J80_02780	COG0101	tRNA pseudouridine synthase activity
J0J80_02785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J0J80_02790	COG1122	ATPase activity
J0J80_02795	COG1122	ATPase activity
J0J80_02805	COG1132	(ABC) transporter
J0J80_02945	COG3328	transposase activity
J0J80_02960	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J0J80_02970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J0J80_02975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J0J80_02980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J0J80_02995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J0J80_03000	COG0581	inorganic phosphate transmembrane transporter activity
J0J80_03005	COG0573	inorganic phosphate transmembrane transporter activity
J0J80_03015	COG5002	protein histidine kinase activity
J0J80_03020	COG0745	RESPONSE REGULATOR receiver
J0J80_03030	COG0590	tRNA wobble adenosine to inosine editing
J0J80_03065	COG1435	thymidine kinase activity
J0J80_03070	COG1619	proteins homologs of microcin C7 resistance protein MccF
J0J80_03075	COG1473	amidohydrolase
J0J80_03080	COG3300	MHYT domain
J0J80_03080	COG5001	Diguanylate cyclase
J0J80_03085	COG0789	Transcriptional regulator
J0J80_03105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0J80_03110	COG0163	prenyltransferase activity
J0J80_03115	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J0J80_03120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J0J80_03135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J0J80_03150	COG0281	malic enzyme
J0J80_03165	COG0622	Phosphoesterase
J0J80_03170	COG0174	glutamine synthetase
J0J80_03185	COG0284	orotidine-5'-phosphate decarboxylase activity
J0J80_03200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J0J80_03210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J0J80_03215	COG0540	Belongs to the ATCase OTCase family
J0J80_03225	COG1418	mRNA catabolic process
J0J80_03245	COG0706	membrane insertase activity
J0J80_03250	COG0706	membrane insertase activity
J0J80_03260	COG0426	domain, Protein
J0J80_03280	COG1454	alcohol dehydrogenase
J0J80_03280	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_03290	COG2252	PERMEase
J0J80_03305	COG1363	Peptidase, m42
J0J80_03310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J0J80_03330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J0J80_03335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J0J80_03340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J0J80_03360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J0J80_03395	COG4464	protein tyrosine phosphatase activity
J0J80_03420	COG4607	ABC-type enterochelin transport system periplasmic component
J0J80_03425	COG4604	ABC transporter, ATP-binding protein
J0J80_03430	COG4605	iron ion homeostasis
J0J80_03435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J0J80_03440	COG4977	sequence-specific DNA binding
J0J80_03440	COG1917	Cupin 2, conserved barrel domain protein
J0J80_03460	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J0J80_03465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J0J80_03470	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J0J80_03485	COG0534	Mate efflux family protein
J0J80_03490	COG1098	S1 RNA binding domain
J0J80_03520	COG1575	Belongs to the MenA family. Type 1 subfamily
J0J80_03525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J0J80_03530	COG3956	TIGRFAM MazG family protein
J0J80_03535	COG2244	polysaccharide biosynthetic process
J0J80_03540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J0J80_03570	COG1846	Transcriptional regulator
J0J80_03575	COG3314	Sporulation integral membrane protein YlbJ
J0J80_03605	COG5002	protein histidine kinase activity
J0J80_03605	COG3850	Histidine kinase
J0J80_03675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J0J80_03680	COG0151	Belongs to the GarS family
J0J80_03690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J0J80_03695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J0J80_03700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J0J80_03705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J0J80_03715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J0J80_03720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J0J80_03730	COG0516	GMP reductase activity
J0J80_03730	COG0517	IMP dehydrogenase activity
J0J80_03735	COG2002	toxin-antitoxin pair type II binding
J0J80_03740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J0J80_03745	COG0193	aminoacyl-tRNA hydrolase activity
J0J80_03750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J0J80_03755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J0J80_03760	COG2088	sporulation resulting in formation of a cellular spore
J0J80_03765	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J0J80_03770	COG4466	Protein conserved in bacteria
J0J80_03780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J0J80_03785	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J0J80_03790	COG1078	dGTPase activity
J0J80_03800	COG4844	belongs to the
J0J80_03805	COG0280	phosphate acetyltransferase
J0J80_03810	COG3773	Cell wall hydrolase
J0J80_03820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J0J80_03835	COG0537	adenosine 5'-monophosphoramidase activity
J0J80_03845	COG0142	geranyltranstransferase activity
J0J80_03850	COG0561	phosphatase activity
J0J80_03855	COG1592	Rubrerythrin
J0J80_03860	COG1592	Rubrerythrin
J0J80_03865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0J80_03870	COG1882	Formate acetyltransferase
J0J80_03880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0J80_03885	COG2011	ABC-type metal ion transport system permease component
J0J80_03890	COG1464	Belongs to the NlpA lipoprotein family
J0J80_03900	COG1115	amino acid carrier protein
J0J80_03925	COG3546	catalase activity
J0J80_03940	COG3546	catalase activity
J0J80_03945	COG0659	secondary active sulfate transmembrane transporter activity
J0J80_03950	COG0513	Belongs to the DEAD box helicase family
J0J80_03955	COG0488	(ABC) transporter
J0J80_03975	COG1266	CAAX protease self-immunity
J0J80_03985	COG0393	Putative heavy-metal-binding
J0J80_03995	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
J0J80_04000	COG0217	transcriptional regulatory protein
J0J80_04015	COG1131	(ABC) transporter
J0J80_04030	COG1979	alcohol dehydrogenase
J0J80_04040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J0J80_04055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J0J80_04065	COG1408	metallophosphoesterase
J0J80_04075	COG1397	ADP-ribosylglycohydrolase
J0J80_04080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_04090	COG1876	peptidase activity
J0J80_04100	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_04100	COG2247	cell wall binding repeat
J0J80_04105	COG1741	Belongs to the pirin family
J0J80_04115	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J0J80_04120	COG2610	gluconate transmembrane transporter activity
J0J80_04125	COG3620	sequence-specific DNA binding
J0J80_04145	COG1408	metallophosphoesterase
J0J80_04150	COG1114	Component of the transport system for branched-chain amino acids
J0J80_04160	COG0789	Transcriptional regulator
J0J80_04160	COG4978	Transcriptional regulator
J0J80_04205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J0J80_04210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_04220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0J80_04220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J0J80_04225	COG2824	Alkylphosphonate utilization operon protein PhnA
J0J80_04250	COG1357	PFAM Pentapeptide repeats (8 copies)
J0J80_04255	COG0786	glutamate:sodium symporter activity
J0J80_04285	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J0J80_04290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J0J80_04295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J0J80_04300	COG0187	DNA topoisomerase II activity
J0J80_04305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J0J80_04310	COG2501	S4 domain
J0J80_04315	COG4481	Protein conserved in bacteria
J0J80_04320	COG0668	transmembrane transport
J0J80_04325	COG1475	DNA binding
J0J80_04330	COG1192	Involved in chromosome partitioning
J0J80_04350	COG0445	tRNA wobble uridine modification
J0J80_04355	COG4152	abc transporter atp-binding protein
J0J80_04360	COG1668	transmembrane transport
J0J80_04365	COG0592	DNA-directed DNA polymerase activity
J0J80_04370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J0J80_04390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J0J80_04400	COG0017	Asparaginyl-tRNA synthetase
J0J80_04410	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_04420	COG0018	arginyl-trna synthetase
J0J80_04480	COG0504	CTP synthase activity
J0J80_04485	COG3706	GGDEF domain
J0J80_04490	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J0J80_04515	COG0745	RESPONSE REGULATOR receiver
J0J80_04520	COG2770	Histidine kinase
J0J80_04520	COG2205	protein histidine kinase activity
J0J80_04525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J0J80_04530	COG1592	Rubrerythrin
J0J80_04540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J0J80_04545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J0J80_04560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J0J80_04575	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
J0J80_04590	COG0366	Alpha amylase catalytic
J0J80_04595	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J0J80_04610	COG2203	Gaf domain
J0J80_04610	COG3706	GGDEF domain
J0J80_04610	COG4251	negative regulation of phosphorylation
J0J80_04610	COG5001	Diguanylate cyclase
J0J80_04620	COG1595	DNA-templated transcription, initiation
J0J80_04630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0J80_04635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J0J80_04650	COG0475	glutathione-regulated potassium exporter activity
J0J80_04660	COG1494	fructose-1,6-bisphosphatase
J0J80_04690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J0J80_04710	COG0251	oxidation-reduction process
J0J80_04715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J0J80_04720	COG0215	cysteine-tRNA ligase activity
J0J80_04725	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J0J80_04730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0J80_04740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J0J80_04745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J0J80_04755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J0J80_04760	COG0081	regulation of translation
J0J80_04765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J0J80_04770	COG0222	ribosome binding
J0J80_04775	COG2813	Specifically methylates the guanine in position
J0J80_04780	COG0085	RNA polymerase activity
J0J80_04785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J0J80_04790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J0J80_04795	COG0049	tRNA binding
J0J80_04800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J0J80_04805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J0J80_04810	COG0051	transcription antitermination factor activity, RNA binding
J0J80_04820	COG0088	Forms part of the polypeptide exit tunnel
J0J80_04825	COG0089	rRNA binding
J0J80_04830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J0J80_04835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J0J80_04840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J0J80_04845	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J0J80_04850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J0J80_04880	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J0J80_04885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J0J80_04895	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J0J80_04900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J0J80_04915	COG0201	protein transport
J0J80_04920	COG0563	adenylate kinase activity
J0J80_04925	COG0024	Methionine aminopeptidase
J0J80_04935	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J0J80_04945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J0J80_04950	COG0202	RNA polymerase activity
J0J80_04960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J0J80_04970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0J80_04975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J0J80_04980	COG1846	Transcriptional regulator
J0J80_04985	COG0534	Mate efflux family protein
J0J80_04990	COG2608	mercury ion transmembrane transporter activity
J0J80_04995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J0J80_05020	COG2267	carboxylic ester hydrolase activity
J0J80_05025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0J80_05035	COG1181	Belongs to the D-alanine--D-alanine ligase family
J0J80_05045	COG0740	serine-type endopeptidase activity
J0J80_05055	COG1546	Belongs to the CinA family
J0J80_05055	COG1058	Belongs to the CinA family
J0J80_05065	COG0149	triose-phosphate isomerase activity
J0J80_05080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_05085	COG2188	Transcriptional regulator
J0J80_05090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J0J80_05110	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J0J80_05125	COG3859	Proton-coupled thiamine transporter YuaJ
J0J80_05140	COG0561	phosphatase activity
J0J80_05145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J0J80_05150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J0J80_05155	COG2183	response to ionizing radiation
J0J80_05175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0J80_05180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J0J80_05185	COG1846	Transcriptional regulator
J0J80_05190	COG1686	Belongs to the peptidase S11 family
J0J80_05200	COG4106	trans-aconitate 2-methyltransferase activity
J0J80_05210	COG1752	Esterase of the alpha-beta hydrolase superfamily
J0J80_05215	COG1525	nuclease
J0J80_05240	COG0778	Nitroreductase
J0J80_05245	COG4894	glucomannan catabolic process
J0J80_05255	COG1472	Belongs to the glycosyl hydrolase 3 family
J0J80_05270	COG4604	ABC transporter, ATP-binding protein
J0J80_05280	COG1881	PFAM PEBP family protein
J0J80_05285	COG1428	Deoxynucleoside kinase
J0J80_05300	COG1396	sequence-specific DNA binding
J0J80_05310	COG2207	Transcriptional regulator
J0J80_05320	COG0351	phosphomethylpyrimidine kinase
J0J80_05325	COG0351	phosphomethylpyrimidine kinase
J0J80_05335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J0J80_05340	COG1328	CTP reductase activity
J0J80_05345	COG1114	Component of the transport system for branched-chain amino acids
J0J80_05370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J0J80_05385	COG3328	transposase activity
J0J80_05390	COG1288	antiporter activity
J0J80_05400	COG0628	permease
J0J80_05405	COG0110	maltose O-acetyltransferase activity
J0J80_05425	COG3328	transposase activity
J0J80_05445	COG1819	glycosyl
J0J80_05455	COG2070	2-Nitropropane dioxygenase
J0J80_05465	COG0439	Biotin carboxylase
J0J80_05470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J0J80_05475	COG0825	malonyl-CoA metabolic process
J0J80_05490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J0J80_05500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J0J80_05505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J0J80_05510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J0J80_05515	COG0739	heme binding
J0J80_05590	COG0802	atpase or kinase
J0J80_05595	COG1214	PFAM Peptidase M22, glycoprotease
J0J80_05615	COG0488	(ABC) transporter
J0J80_05620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
J0J80_05630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J0J80_05645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J0J80_05650	COG0459	protein refolding
J0J80_05655	COG0736	holo-[acyl-carrier-protein] synthase activity
J0J80_05660	COG2155	Conserved Protein
J0J80_05665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J0J80_05670	COG0745	RESPONSE REGULATOR receiver
J0J80_05675	COG5002	protein histidine kinase activity
J0J80_05680	COG0436	Aminotransferase
J0J80_05685	COG4991	sh3 domain protein
J0J80_05685	COG0860	N-Acetylmuramoyl-L-alanine amidase
J0J80_05685	COG3103	Sh3 type 3 domain protein
J0J80_05690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_05695	COG2137	regulation of response to DNA damage stimulus
J0J80_05700	COG2188	Transcriptional regulator
J0J80_05715	COG0366	Alpha amylase catalytic
J0J80_05720	COG0739	heme binding
J0J80_05725	COG4536	flavin adenine dinucleotide binding
J0J80_05735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0J80_05740	COG1597	lipid kinase activity
J0J80_05750	COG4193	domain, Protein
J0J80_05750	COG5263	repeat protein
J0J80_05765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J0J80_05770	COG0210	DNA helicase
J0J80_05775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J0J80_05785	COG0784	Response regulator, receiver
J0J80_05785	COG2205	protein histidine kinase activity
J0J80_05790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J0J80_05795	COG3583	domain protein
J0J80_05800	COG1950	PFAM Membrane protein of
J0J80_05815	COG0546	phosphoglycolate phosphatase activity
J0J80_05840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J0J80_05845	COG1481	regulation of sporulation
J0J80_05860	COG0148	phosphopyruvate hydratase activity
J0J80_05865	COG0628	permease
J0J80_05870	COG0530	calcium, potassium:sodium antiporter activity
J0J80_05880	COG0557	exoribonuclease II activity
J0J80_05885	COG2843	Capsule synthesis protein
J0J80_05890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J0J80_05910	COG1696	Membrane protein involved in D-alanine export
J0J80_05920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J0J80_05925	COG1116	anion transmembrane transporter activity
J0J80_05930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J0J80_05940	COG1175	transmembrane transport
J0J80_05945	COG0395	ABC-type sugar transport system, permease component
J0J80_05950	COG1653	transport
J0J80_05955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J0J80_05960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J0J80_05965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J0J80_05970	COG3328	transposase activity
J0J80_05975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J0J80_05985	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J0J80_05990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J0J80_06005	COG1272	protein, Hemolysin III
J0J80_06010	COG3681	Belongs to the UPF0597 family
J0J80_06015	COG2268	Band 7 protein
J0J80_06020	COG1876	peptidase activity
J0J80_06035	COG0628	permease
J0J80_06045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0J80_06050	COG2217	Heavy metal translocating P-type atpase
J0J80_06060	COG5002	protein histidine kinase activity
J0J80_06065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_06085	COG5001	Diguanylate cyclase
J0J80_06090	COG3300	MHYT domain
J0J80_06090	COG5001	Diguanylate cyclase
J0J80_06100	COG1937	Protein conserved in bacteria
J0J80_06105	COG2217	Heavy metal translocating P-type atpase
J0J80_06110	COG2217	Heavy metal translocating P-type atpase
J0J80_06120	COG1131	(ABC) transporter
J0J80_06140	COG5002	protein histidine kinase activity
J0J80_06165	COG0534	Mate efflux family protein
J0J80_06175	COG0590	tRNA wobble adenosine to inosine editing
J0J80_06205	COG1234	tRNA 3'-trailer cleavage
J0J80_06210	COG0346	lactoylglutathione lyase activity
J0J80_06225	COG1501	Belongs to the glycosyl hydrolase 31 family
J0J80_06230	COG0561	phosphatase activity
J0J80_06240	COG2207	Transcriptional regulator
J0J80_06245	COG0277	FAD linked oxidase domain protein
J0J80_06250	COG0534	Mate efflux family protein
J0J80_06255	COG2033	superoxide reductase activity
J0J80_06270	COG0748	coenzyme F420 binding
J0J80_06280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J0J80_06290	COG3344	reverse transcriptase
J0J80_06300	COG2364	Membrane
J0J80_06305	COG2207	Transcriptional regulator
J0J80_06310	COG2818	Glycosylase
J0J80_06330	COG1136	(ABC) transporter
J0J80_06375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J0J80_06390	COG1187	pseudouridine synthase activity
J0J80_06400	COG4807	Protein conserved in bacteria
J0J80_06425	COG0019	diaminopimelate decarboxylase activity
J0J80_06435	COG1473	amidohydrolase
J0J80_06440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J0J80_06455	COG2171	N-acyltransferase activity
J0J80_06460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J0J80_06475	COG0640	Transcriptional regulator
J0J80_06480	COG0730	response to heat
J0J80_06485	COG2378	regulation of single-species biofilm formation
J0J80_06490	COG1473	amidohydrolase
J0J80_06495	COG2723	6-phospho-beta-galactosidase activity
J0J80_06500	COG0768	penicillin binding
J0J80_06540	COG0732	type I restriction modification DNA specificity domain
J0J80_06545	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J0J80_06560	COG2003	Belongs to the UPF0758 family
J0J80_06620	COG1136	(ABC) transporter
J0J80_06625	COG2003	Belongs to the UPF0758 family
J0J80_06770	COG0583	DNA-binding transcription factor activity
J0J80_06790	COG0067	glutamate synthase
J0J80_06790	COG0069	glutamate synthase activity
J0J80_06790	COG0070	glutamate synthase
J0J80_06810	COG1533	DNA photolyase activity
J0J80_06815	COG3711	transcriptional antiterminator
J0J80_06820	COG1263	PTS System
J0J80_06820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_06820	COG2190	(PTS) system
J0J80_06825	COG2723	6-phospho-beta-galactosidase activity
J0J80_06830	COG1316	TRANSCRIPTIONal
J0J80_06835	COG0826	peptidase U32
J0J80_06840	COG2323	membrane
J0J80_06845	COG0037	tRNA processing
J0J80_06865	COG1393	Belongs to the ArsC family
J0J80_06870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0J80_06875	COG3557	Belongs to the UPF0374 family
J0J80_06880	COG2309	aminopeptidase activity
J0J80_06975	COG1175	transmembrane transport
J0J80_06980	COG3833	ABC-type maltose transport systems, permease component
J0J80_06985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J0J80_07020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J0J80_07105	COG3263	regulation of cellular component size
J0J80_07110	COG1192	Involved in chromosome partitioning
J0J80_07130	COG1011	Hydrolase
J0J80_07140	COG0577	efflux transmembrane transporter activity
J0J80_07145	COG1136	(ABC) transporter
J0J80_07150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J0J80_07155	COG0583	DNA-binding transcription factor activity
J0J80_07160	COG3620	sequence-specific DNA binding
J0J80_07165	COG0393	Putative heavy-metal-binding
J0J80_07185	COG2207	Transcriptional regulator
J0J80_07190	COG0534	Mate efflux family protein
J0J80_07205	COG2211	Major facilitator Superfamily
J0J80_07210	COG0297	glycogen (starch) synthase activity
J0J80_07215	COG0024	Methionine aminopeptidase
J0J80_07220	COG3250	beta-galactosidase activity
J0J80_07225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0J80_07235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J0J80_07250	COG1609	Transcriptional regulator
J0J80_07255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J0J80_07260	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J0J80_07265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0J80_07270	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J0J80_07290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J0J80_07295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J0J80_07305	COG1811	Na channel or pump
J0J80_07320	COG0006	proline dipeptidase activity
J0J80_07335	COG1283	sodium-dependent phosphate transmembrane transporter activity
J0J80_07340	COG0396	ATPase activity
J0J80_07345	COG0719	Fe-S assembly protein
J0J80_07350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J0J80_07355	COG0822	iron-sulfur transferase activity
J0J80_07360	COG0719	Fe-S assembly protein
J0J80_07375	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J0J80_07380	COG3377	Domain of unknown function (DUF1805)
J0J80_07400	COG0297	glycogen (starch) synthase activity
J0J80_07405	COG0058	SHG alpha-glucan phosphorylase activity
J0J80_07430	COG1595	DNA-templated transcription, initiation
J0J80_07435	COG1403	HNH endonuclease
J0J80_07440	COG3328	transposase activity
J0J80_07455	COG0659	secondary active sulfate transmembrane transporter activity
J0J80_07460	COG1061	Type III restriction enzyme res subunit
J0J80_07480	COG0613	PHP domain protein
J0J80_07490	COG1592	Rubrerythrin
J0J80_07500	COG3328	transposase activity
J0J80_07505	COG1823	symporter activity
J0J80_07510	COG2340	Cysteine-rich secretory protein family
J0J80_07515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J0J80_07520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J0J80_07540	COG4667	esterase of the alpha-beta hydrolase superfamily
J0J80_07545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J0J80_07550	COG0242	peptide deformylase activity
J0J80_07590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J0J80_07595	COG2011	ABC-type metal ion transport system permease component
J0J80_07600	COG1464	Belongs to the NlpA lipoprotein family
J0J80_07605	COG1473	amidohydrolase
J0J80_07620	COG2985	domain, Protein
J0J80_07625	COG2078	PFAM AMMECR1 domain protein
J0J80_07625	COG3885	ferrous iron binding
J0J80_07650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_07670	COG1609	Transcriptional regulator
J0J80_07680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_07685	COG1621	beta-fructofuranosidase activity
J0J80_07700	COG3328	transposase activity
J0J80_07710	COG0513	Belongs to the DEAD box helicase family
J0J80_07715	COG2364	Membrane
J0J80_07720	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_07725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0J80_07730	COG3481	metal-dependent phosphohydrolase, HD sub domain
J0J80_07735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J0J80_07765	COG3290	protein histidine kinase activity
J0J80_07800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J0J80_07805	COG0297	glycogen (starch) synthase activity
J0J80_07810	COG0302	gtp cyclohydrolase
J0J80_07820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J0J80_07825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J0J80_07830	COG0457	Tetratricopeptide repeat
J0J80_07835	COG2738	Putative neutral zinc metallopeptidase
J0J80_07840	COG1595	DNA-templated transcription, initiation
J0J80_07850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_07855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J0J80_07860	COG0617	tRNA 3'-terminal CCA addition
J0J80_07870	COG3935	DnaD domain protein
J0J80_07875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J0J80_07880	COG4499	WXG100 protein secretion system (Wss), protein YukC
J0J80_07880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J0J80_07885	COG3331	DNA recombination
J0J80_07900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J0J80_07915	COG1692	metallophosphoesterase
J0J80_07920	COG2359	stage V sporulation protein S
J0J80_07925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0J80_07930	COG4550	Control of competence regulator ComK, YlbF/YmcA
J0J80_07940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J0J80_07945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J0J80_07950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J0J80_07955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0J80_07975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J0J80_07985	COG3763	UPF0154 protein
J0J80_07995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J0J80_08000	COG0187	DNA topoisomerase II activity
J0J80_08005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J0J80_08020	COG1702	phosphate starvation-inducible protein PhoH
J0J80_08025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J0J80_08030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J0J80_08035	COG0295	cytidine deaminase activity
J0J80_08050	COG1381	Involved in DNA repair and RecF pathway recombination
J0J80_08055	COG0423	glycine-tRNA ligase activity
J0J80_08060	COG0358	DNA primase activity
J0J80_08065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0J80_08070	COG2384	SAM-dependent methyltransferase
J0J80_08075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J0J80_08080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J0J80_08085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J0J80_08085	COG0072	phenylalanine-tRNA ligase activity
J0J80_08090	COG1605	Chorismate mutase
J0J80_08090	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J0J80_08095	COG1609	Transcriptional regulator
J0J80_08110	COG0583	DNA-binding transcription factor activity
J0J80_08120	COG1956	GAF domain-containing protein
J0J80_08130	COG1104	cysteine desulfurase activity
J0J80_08140	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_08140	COG1454	alcohol dehydrogenase
J0J80_08170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J0J80_08175	COG0779	Required for maturation of 30S ribosomal subunits
J0J80_08180	COG0195	Participates in both transcription termination and antitermination
J0J80_08185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J0J80_08200	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J0J80_08205	COG1368	sulfuric ester hydrolase activity
J0J80_08215	COG0322	excinuclease ABC activity
J0J80_08220	COG2197	response regulator
J0J80_08240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J0J80_08250	COG0622	Phosphoesterase
J0J80_08280	COG1496	oxidoreductase activity
J0J80_08285	COG0569	domain protein
J0J80_08290	COG0569	domain protein
J0J80_08300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_08305	COG0561	phosphatase activity
J0J80_08315	COG0242	peptide deformylase activity
J0J80_08345	COG0772	Belongs to the SEDS family
J0J80_08365	COG4471	UPF0298 protein
J0J80_08370	COG0228	four-way junction DNA binding
J0J80_08375	COG1837	Belongs to the UPF0109 family
J0J80_08415	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J0J80_08420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J0J80_08435	COG0181	hydroxymethylbilane synthase activity
J0J80_08445	COG0113	porphobilinogen synthase activity
J0J80_08450	COG1648	precorrin-2 dehydrogenase activity
J0J80_08450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J0J80_08455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J0J80_08460	COG0765	amino acid transport
J0J80_08465	COG1126	abc transporter atp-binding protein
J0J80_08480	COG2207	Transcriptional regulator
J0J80_08480	COG4753	response regulator
J0J80_08500	COG0110	maltose O-acetyltransferase activity
J0J80_08510	COG1846	Transcriptional regulator
J0J80_08515	COG0386	Belongs to the glutathione peroxidase family
J0J80_08530	COG0596	Alpha beta hydrolase
J0J80_08550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J0J80_08575	COG2723	6-phospho-beta-galactosidase activity
J0J80_08580	COG1447	Phosphotransferase system cellobiose-specific component IIA
J0J80_08590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J0J80_08595	COG2723	6-phospho-beta-galactosidase activity
J0J80_08600	COG1486	melibiose metabolic process
J0J80_08605	COG4086	secreted protein
J0J80_08625	COG2720	vancomycin resistance protein
J0J80_08635	COG1929	Belongs to the glycerate kinase type-1 family
J0J80_08645	COG4260	virion core protein, lumpy skin disease virus
J0J80_08655	COG1842	Phage shock protein A
J0J80_08670	COG2244	polysaccharide biosynthetic process
J0J80_08685	COG1187	pseudouridine synthase activity
J0J80_08690	COG0613	PHP domain protein
J0J80_08700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J0J80_08710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J0J80_08715	COG1674	ftsk spoiiie
J0J80_08720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J0J80_08745	COG0489	protein tyrosine kinase activity
J0J80_08750	COG1323	Belongs to the UPF0348 family
J0J80_08755	COG1399	metal-binding, possibly nucleic acid-binding protein
J0J80_08760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J0J80_08805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J0J80_08810	COG0513	Belongs to the DEAD box helicase family
J0J80_08815	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J0J80_08825	COG0543	2 iron, 2 sulfur cluster binding
J0J80_08830	COG0493	'glutamate synthase
J0J80_08830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J0J80_08840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J0J80_08845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J0J80_08850	COG0768	penicillin binding
J0J80_08855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J0J80_08865	COG1940	carbohydrate kinase activity
J0J80_08870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J0J80_08875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J0J80_08900	COG4537	Required for transformation and DNA binding
J0J80_08905	COG1459	type II secretion system
J0J80_08910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J0J80_08925	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J0J80_08945	COG0640	Transcriptional regulator
J0J80_08965	COG0004	ammonium transporteR
J0J80_08970	COG0658	competence protein
J0J80_08970	COG2333	competence protein COMEC
J0J80_08975	COG4166	transmembrane transport
J0J80_08980	COG0488	(ABC) transporter
J0J80_08995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J0J80_08995	COG1199	ATP-dependent helicase activity
J0J80_09005	COG1132	(ABC) transporter
J0J80_09010	COG1132	(ABC) transporter
J0J80_09015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J0J80_09020	COG2195	Cleaves the N-terminal amino acid of tripeptides
J0J80_09030	COG0564	pseudouridine synthase activity
J0J80_09060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J0J80_09080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J0J80_09130	COG0312	modulator of DNA gyrase
J0J80_09145	COG4988	ABC transporter
J0J80_09150	COG1132	(ABC) transporter
J0J80_09160	COG2832	Protein of unknown function (DUF454)
J0J80_09185	COG4372	Transposase
J0J80_09210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J0J80_09215	COG3022	response to hydroperoxide
J0J80_09240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_09240	COG2190	(PTS) system
J0J80_09240	COG1263	PTS System
J0J80_09265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J0J80_09295	COG1619	proteins homologs of microcin C7 resistance protein MccF
J0J80_09315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J0J80_09315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J0J80_09320	COG1268	BioY protein
J0J80_09345	COG1705	Flagellar rod assembly protein muramidase FlgJ
J0J80_09380	COG1061	Type III restriction enzyme res subunit
J0J80_09385	COG0494	nUDIX hydrolase
J0J80_09400	COG0584	glycerophosphoryl diester phosphodiesterase
J0J80_09420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J0J80_09435	COG1349	DNA-binding transcription factor activity
J0J80_09440	COG1105	Belongs to the carbohydrate kinase PfkB family
J0J80_09445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0J80_09445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J0J80_09445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J0J80_09480	COG0708	Exodeoxyribonuclease III
J0J80_09485	COG5002	protein histidine kinase activity
J0J80_09490	COG0745	RESPONSE REGULATOR receiver
J0J80_09530	COG0640	Transcriptional regulator
J0J80_09535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J0J80_09540	COG0534	Mate efflux family protein
J0J80_09570	COG0720	synthase
J0J80_09575	COG0602	queuosine metabolic process
J0J80_09580	COG0302	gtp cyclohydrolase
J0J80_09585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J0J80_09590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J0J80_09595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J0J80_09605	COG1621	beta-fructofuranosidase activity
J0J80_09610	COG1803	Methylglyoxal synthase
J0J80_09620	COG0671	phosphoesterase, PA-phosphatase related
J0J80_09635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J0J80_09650	COG4166	transmembrane transport
J0J80_09655	COG0601	transmembrane transport
J0J80_09660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J0J80_09665	COG0444	Belongs to the ABC transporter superfamily
J0J80_09695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J0J80_09710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0J80_09715	COG1570	exodeoxyribonuclease VII activity
J0J80_09725	COG0142	geranyltranstransferase activity
J0J80_09730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J0J80_09735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J0J80_09740	COG0497	DNA recombination
J0J80_09745	COG0750	zinc metalloprotease
J0J80_09750	COG0745	RESPONSE REGULATOR receiver
J0J80_09755	COG1649	PFAM Uncharacterised BCR, COG1649
J0J80_09765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J0J80_09780	COG0735	belongs to the Fur family
J0J80_09785	COG4974	Belongs to the 'phage' integrase family
J0J80_09795	COG1827	regulation of RNA biosynthetic process
J0J80_09835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J0J80_09840	COG0366	Alpha amylase catalytic
J0J80_09845	COG1263	PTS System
J0J80_09845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_09845	COG2190	(PTS) system
J0J80_09880	COG0366	Alpha amylase catalytic
J0J80_09910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J0J80_09915	COG3326	Membrane
J0J80_09925	COG2827	Endonuclease containing a URI domain
J0J80_09935	COG0534	Mate efflux family protein
J0J80_09945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J0J80_09955	COG0737	Belongs to the 5'-nucleotidase family
J0J80_09980	COG1757	Na H antiporter
J0J80_10040	COG1115	amino acid carrier protein
J0J80_10050	COG1307	EDD domain protein, DegV family
J0J80_10055	COG1671	Belongs to the UPF0178 family
J0J80_10060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_10065	COG4129	membrane
J0J80_10080	COG1550	Protein conserved in bacteria
J0J80_10085	COG0628	permease
J0J80_10095	COG0534	Mate efflux family protein
J0J80_10100	COG1522	sequence-specific DNA binding
J0J80_10105	COG0436	Aminotransferase
J0J80_10115	COG0596	Alpha beta hydrolase
J0J80_10120	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_10125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J0J80_10135	COG4377	Putative membrane peptidase family (DUF2324)
J0J80_10140	COG0640	Transcriptional regulator
J0J80_10150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J0J80_10185	COG0180	Tryptophanyl-tRNA synthetase
J0J80_10210	COG0473	3-isopropylmalate dehydrogenase activity
J0J80_10285	COG4824	toxin secretion phage lysis holin
J0J80_10290	COG1388	LysM domain
J0J80_10290	COG3409	Peptidoglycan-binding domain 1 protein
J0J80_10290	COG5632	N-Acetylmuramoyl-L-alanine amidase
J0J80_10325	COG3328	transposase activity
J0J80_10340	COG3328	transposase activity
J0J80_10355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J0J80_10380	COG2826	transposase and inactivated derivatives, IS30 family
J0J80_10410	COG5002	protein histidine kinase activity
J0J80_10445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J0J80_10450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J0J80_10505	COG1388	LysM domain
J0J80_10505	COG3409	Peptidoglycan-binding domain 1 protein
J0J80_10505	COG5632	N-Acetylmuramoyl-L-alanine amidase
J0J80_10530	COG1196	nuclear chromosome segregation
J0J80_10560	COG3597	protein domain associated with
J0J80_10565	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J0J80_10605	COG1401	restriction endodeoxyribonuclease activity
J0J80_10620	COG1061	Type III restriction enzyme res subunit
J0J80_10650	COG0534	Mate efflux family protein
J0J80_10675	COG1331	Highly conserved protein containing a thioredoxin domain
J0J80_10690	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_10695	COG0367	asparagine synthase
J0J80_10700	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J0J80_10710	COG0252	asparaginase activity
J0J80_10720	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J0J80_10725	COG4120	Belongs to the binding-protein-dependent transport system permease family
J0J80_10740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J0J80_10740	COG0723	plastoquinol--plastocyanin reductase activity
J0J80_10760	COG0733	neurotransmitter:sodium symporter activity
J0J80_10785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J0J80_10790	COG0010	Belongs to the arginase family
J0J80_10795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J0J80_10800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J0J80_10805	COG1982	Orn Lys Arg decarboxylase major
J0J80_10810	COG3706	GGDEF domain
J0J80_10830	COG4974	Belongs to the 'phage' integrase family
J0J80_10845	COG1523	belongs to the glycosyl hydrolase 13 family
J0J80_10865	COG0438	transferase activity, transferring glycosyl groups
J0J80_10870	COG0463	Glycosyl transferase, family 2
J0J80_10885	COG1028	Short-chain dehydrogenase reductase Sdr
J0J80_10895	COG0800	Aldolase
J0J80_10920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J0J80_10930	COG4720	Psort location CytoplasmicMembrane, score
J0J80_10935	COG2081	HI0933 family
J0J80_10970	COG0463	Glycosyl transferase, family 2
J0J80_10970	COG0457	Tetratricopeptide repeat
J0J80_11000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J0J80_11005	COG1177	transmembrane transport
J0J80_11010	COG1176	ABC-type spermidine putrescine transport system, permease component I
J0J80_11015	COG3842	ATPase activity
J0J80_11025	COG1217	gtp-binding protein TYPA
J0J80_11030	COG1466	dna polymerase III delta subunit
J0J80_11035	COG0658	competence protein
J0J80_11035	COG2333	competence protein COMEC
J0J80_11040	COG1596	polysaccharide export
J0J80_11040	COG1555	photosystem II stabilization
J0J80_11050	COG2226	methyltransferase
J0J80_11055	COG0799	negative regulation of ribosome biogenesis
J0J80_11060	COG1713	HD superfamily hydrolase involved in NAD metabolism
J0J80_11065	COG1534	Rna-binding protein
J0J80_11070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J0J80_11075	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J0J80_11085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J0J80_11085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J0J80_11090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J0J80_11095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J0J80_11100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J0J80_11105	COG0572	uridine kinase
J0J80_11110	COG0826	peptidase U32
J0J80_11115	COG0826	peptidase U32
J0J80_11120	COG4122	O-methyltransferase activity
J0J80_11125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J0J80_11130	COG3906	Belongs to the UPF0473 family
J0J80_11145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J0J80_11155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J0J80_11160	COG0482	sulfurtransferase activity
J0J80_11165	COG1079	Belongs to the binding-protein-dependent transport system permease family
J0J80_11170	COG4603	Belongs to the binding-protein-dependent transport system permease family
J0J80_11175	COG3845	ABC transporter
J0J80_11180	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_11185	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_11190	COG1744	ABC transporter substrate-binding protein PnrA-like
J0J80_11195	COG1674	ftsk spoiiie
J0J80_11195	COG1280	lysine exporter protein (LysE YggA)
J0J80_11200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J0J80_11210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J0J80_11215	COG0527	aspartate kinase activity
J0J80_11220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J0J80_11225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J0J80_11235	COG0726	polysaccharide deacetylase
J0J80_11245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J0J80_11250	COG0196	riboflavin kinase activity
J0J80_11260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J0J80_11270	COG0481	GTPase activity
J0J80_11285	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J0J80_11295	COG2195	Cleaves the N-terminal amino acid of tripeptides
J0J80_11300	COG1983	PspC domain protein
J0J80_11310	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J0J80_11315	COG0268	Binds directly to 16S ribosomal RNA
J0J80_11350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J0J80_11355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J0J80_11360	COG1610	YqeY-like protein
J0J80_11370	COG2348	transferase activity, transferring amino-acyl groups
J0J80_11375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J0J80_11380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J0J80_11385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J0J80_11390	COG2264	protein methyltransferase activity
J0J80_11395	COG0484	heat shock protein binding
J0J80_11400	COG0443	Heat shock 70 kDa protein
J0J80_11405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J0J80_11410	COG1420	regulation of RNA biosynthetic process
J0J80_11420	COG1126	abc transporter atp-binding protein
J0J80_11425	COG0765	amino acid transport
J0J80_11435	COG1193	negative regulation of DNA recombination
J0J80_11445	COG0457	Tetratricopeptide repeat
J0J80_11445	COG0705	Rhomboid family
J0J80_11450	COG0564	pseudouridine synthase activity
J0J80_11455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J0J80_11490	COG0762	integral membrane protein
J0J80_11495	COG1799	cell septum assembly
J0J80_11500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J0J80_11505	COG1873	PFAM PRC-barrel domain
J0J80_11510	COG1191	sigma factor activity
J0J80_11515	COG1191	sigma factor activity
J0J80_11525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J0J80_11545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J0J80_11550	COG0772	Belongs to the SEDS family
J0J80_11555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J0J80_11560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J0J80_11565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J0J80_11570	COG0768	penicillin binding
J0J80_11575	COG0768	penicillin binding
J0J80_11585	COG0275	rRNA processing
J0J80_11590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J0J80_11600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J0J80_11605	COG0544	peptidyl-prolyl cis-trans isomerase activity
J0J80_11640	COG1247	-acetyltransferase
J0J80_11675	COG0210	DNA helicase
J0J80_11695	COG0673	inositol 2-dehydrogenase activity
J0J80_11700	COG1114	Component of the transport system for branched-chain amino acids
J0J80_11715	COG0475	glutathione-regulated potassium exporter activity
J0J80_11735	COG1227	inorganic diphosphatase activity
J0J80_11740	COG1164	Oligoendopeptidase f
J0J80_11745	COG2271	Major facilitator Superfamily
J0J80_11750	COG2267	carboxylic ester hydrolase activity
J0J80_11760	COG2176	DNA-directed DNA polymerase activity
J0J80_11765	COG0442	prolyl-tRNA aminoacylation
J0J80_11770	COG0750	zinc metalloprotease
J0J80_11780	COG4589	Belongs to the CDS family
J0J80_11785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J0J80_11810	COG0233	cytoplasmic translational termination
J0J80_11815	COG0528	UMP kinase activity
J0J80_11820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J0J80_11825	COG0052	Belongs to the universal ribosomal protein uS2 family
J0J80_11835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0J80_11840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J0J80_11855	COG4974	Belongs to the 'phage' integrase family
J0J80_11860	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J0J80_11865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J0J80_11870	COG0758	DNA mediated transformation
J0J80_11875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J0J80_11895	COG0335	large ribosomal subunit rRNA binding
J0J80_11905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J0J80_11935	COG0742	ribosomal rna small subunit methyltransferase
J0J80_11950	COG1785	Belongs to the alkaline phosphatase family
J0J80_11955	COG3328	transposase activity
J0J80_11965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J0J80_11970	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
J0J80_11975	COG0552	protein localization to endoplasmic reticulum
J0J80_11980	COG1196	nuclear chromosome segregation
J0J80_11985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J0J80_12005	COG1012	belongs to the aldehyde dehydrogenase family
J0J80_12020	COG0577	efflux transmembrane transporter activity
J0J80_12030	COG1136	(ABC) transporter
J0J80_12070	COG1115	amino acid carrier protein
J0J80_12100	COG1285	pathogenesis
J0J80_12120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J0J80_12125	COG0732	type I restriction modification DNA specificity domain
J0J80_12130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J0J80_12155	COG1263	PTS System
J0J80_12155	COG2190	(PTS) system
J0J80_12155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J0J80_12255	COG1595	DNA-templated transcription, initiation
J0J80_12275	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J0J80_12290	COG0419	ATPase involved in DNA repair
J0J80_12295	COG0420	3'-5' exonuclease activity
J0J80_12300	COG1609	Transcriptional regulator
J0J80_12315	COG0406	alpha-ribazole phosphatase activity
J0J80_12335	COG4221	oxidoreductase activity
J0J80_12350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J0J80_12355	COG1461	Dihydroxyacetone kinase
J0J80_12360	COG1302	Protein conserved in bacteria
J0J80_12365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J0J80_12395	COG1564	THIamine pyrophosphokinase
J0J80_12400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J0J80_12405	COG1162	GTPase activity
J0J80_12410	COG0515	serine threonine protein kinase
J0J80_12410	COG2815	serine threonine protein kinase
J0J80_12415	COG0631	protein serine/threonine phosphatase activity
J0J80_12425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J0J80_12425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J0J80_12430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_12440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J0J80_12445	COG2996	Protein conserved in bacteria
J0J80_12460	COG0426	domain, Protein
J0J80_12465	COG0346	lactoylglutathione lyase activity
J0J80_12475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J0J80_12485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J0J80_12490	COG1758	RNA polymerase activity
J0J80_12495	COG0194	GDP metabolic process
J0J80_12500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
J0J80_12505	COG2720	vancomycin resistance protein
J0J80_12515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J0J80_12530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J0J80_12535	COG1876	peptidase activity
J0J80_12555	COG0772	Belongs to the SEDS family
J0J80_12560	COG1074	ATP-dependent DNA helicase activity
J0J80_12575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J0J80_12590	COG1160	GTP binding
J0J80_12595	COG0539	negative regulation of cytoplasmic translation
J0J80_12595	COG2183	response to ionizing radiation
J0J80_12610	COG1141	Ferredoxin
J0J80_12615	COG1187	pseudouridine synthase activity
J0J80_12620	COG0700	Nucleoside recognition
J0J80_12625	COG2715	membrane protein required for spore maturation
J0J80_12630	COG1686	Belongs to the peptidase S11 family
J0J80_12640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J0J80_12650	COG0697	spore germination
J0J80_12660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J0J80_12675	COG2172	sigma factor antagonist activity
J0J80_12685	COG1686	Belongs to the peptidase S11 family
J0J80_12720	COG2521	methyltransferase
J0J80_12720	COG2136	Putative SAM-dependent methyltransferase
J0J80_12725	COG0629	single-stranded DNA binding
J0J80_12730	COG0612	Peptidase, M16
J0J80_12735	COG0612	Peptidase, M16
J0J80_12745	COG0813	purine-nucleoside phosphorylase activity
J0J80_12750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J0J80_12755	COG0628	permease
J0J80_12770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J0J80_12825	COG1216	Glycosyl transferase, family 2
J0J80_12835	COG0438	transferase activity, transferring glycosyl groups
J0J80_12840	COG1216	Glycosyl transferase, family 2
J0J80_12840	COG1442	glycosyl transferase family 8
J0J80_12845	COG1216	Glycosyl transferase, family 2
J0J80_12845	COG1442	glycosyl transferase family 8
J0J80_12855	COG1316	TRANSCRIPTIONal
J0J80_12865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J0J80_12870	COG0124	histidyl-tRNA synthetase
J0J80_12880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J0J80_12885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J0J80_12890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J0J80_12890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J0J80_12895	COG2244	polysaccharide biosynthetic process
J0J80_12900	COG2323	membrane
J0J80_12910	COG1862	Preprotein translocase