locus-tag	class	description
HLK68_00005	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_00015	ENOG41082AN	stage II sporulation protein
HLK68_00020	ENOG4105DZ1	carboxypeptidase
HLK68_00025	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HLK68_00045	ENOG4107RIS	Acyl-transferase
HLK68_00050	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HLK68_00055	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HLK68_00060	ENOG4107YX5	Pfam:DUF548
HLK68_00065	ENOG4105CT4	transporter
HLK68_00070	ENOG4105Z8H	single-stranded DNA-binding protein
HLK68_00085	ENOG4105K4I	Scp-like extracellular
HLK68_00090	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HLK68_00095	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HLK68_00100	ENOG4105C02	permease
HLK68_00115	ENOG4105CUZ	uba thif-type nad fad binding protein
HLK68_00130	ENOG4105F9F	transposase
HLK68_00145	ENOG4105E0M	Sulfatase
HLK68_00150	ENOG4105EJV	Membrane
HLK68_00170	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HLK68_00185	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLK68_00190	ENOG4105K64	Glycosyl transferase, family 2
HLK68_00200	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLK68_00225	ENOG4108KGH	TRANSCRIPTIONal
HLK68_00245	ENOG4105CUT	histidyl-tRNA synthetase
HLK68_00250	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HLK68_00255	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HLK68_00260	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HLK68_00265	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HLK68_00270	ENOG4105CKP	Polysaccharide Biosynthesis Protein
HLK68_00275	ENOG4108QG2	Membrane
HLK68_00285	ENOG4105VIE	preprotein translocase, subunit YajC
HLK68_00290	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HLK68_00295	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HLK68_00310	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HLK68_00315	ENOG4105TMB	Formate nitrite transporter
HLK68_00345	ENOG4105C8Y	Acetylornithine aminotransferase
HLK68_00350	ENOG4105CFP	Peptidase U32
HLK68_00355	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HLK68_00370	ENOG4107QM2	Aldo Keto reductase
HLK68_00415	ENOG4105C8J	)-transporter
HLK68_00720	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HLK68_00740	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HLK68_00765	ENOG4105NBR	Pectinesterase
HLK68_00775	ENOG4105F9F	transposase
HLK68_00795	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HLK68_00805	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HLK68_00810	ENOG4108JQ7	(ABC) transporter
HLK68_00815	ENOG4105C3U	ABC transporter
HLK68_00830	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLK68_00835	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HLK68_00840	ENOG4105DKQ	ROK family
HLK68_00855	ENOG4107SCR	N-acetylneuraminate lyase
HLK68_00865	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLK68_00870	ENOG4105K46	50S ribosomal protein l27
HLK68_00880	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HLK68_00885	ENOG4105BZU	Histidine kinase
HLK68_00890	ENOG4108Z4T	Peptidase M50
HLK68_00925	ENOG4105W5Q	DNA repair protein (RadC
HLK68_00935	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HLK68_00960	ENOG4105CN9	Peptidase m42 family protein
HLK68_00965	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HLK68_00970	ENOG4105VJV	50s ribosomal protein L35
HLK68_00975	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HLK68_00985	ENOG4105C22	threonyL-tRNA synthetase
HLK68_01005	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HLK68_01025	ENOG4105DPN	Oligoendopeptidase f
HLK68_01030	ENOG4108XXK	NUDIX hydrolase
HLK68_01035	ENOG4105KFN	sortase, SrtB family
HLK68_01045	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_01050	ENOG4105C2M	dna polymerase I
HLK68_01065	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLK68_01085	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HLK68_01105	ENOG4105EAH	synthase
HLK68_01110	ENOG4105CEP	NADH dehydrogenase
HLK68_01130	ENOG4108Z4K	mutator MutT protein
HLK68_01135	ENOG4105CA9	Pyruvate kinase
HLK68_01140	ENOG4105CTQ	phosphohexokinase
HLK68_01145	ENOG4105C0B	DNA polymerase III (alpha subunit)
HLK68_01150	ENOG4105SFS	phosphoesterase RecJ domain protein
HLK68_01155	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HLK68_01165	ENOG4105KBJ	sporulation protein ytfj
HLK68_01175	ENOG4105CAQ	asparagine synthetase
HLK68_01180	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HLK68_01185	ENOG4105EN6	Membrane
HLK68_01190	ENOG4105C5H	ABC transporter
HLK68_01195	ENOG4105DFM	M18 family aminopeptidase
HLK68_01265	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLK68_01270	ENOG4105D7W	serine acetyltransferase
HLK68_01290	ENOG4105CAY	ferredoxin--nadp reductase
HLK68_01300	ENOG4108W5N	phosphatidylglycerophosphatase a
HLK68_01310	ENOG41083MR	nifu domain-containing protein
HLK68_01315	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HLK68_01320	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HLK68_01325	ENOG4105MMD	transcriptional regulator
HLK68_01330	ENOG4108YTE	sporulation protein YunB
HLK68_01340	ENOG4105UQX	Mate efflux family protein
HLK68_01345	ENOG4105ETE	Transcriptional regulator (LacI family
HLK68_01355	ENOG4105CDA	abc transporter atp-binding protein
HLK68_01360	ENOG4105E5Q	amino acid AbC transporter
HLK68_01385	ENOG4105DQ6	Transposase
HLK68_01395	ENOG4105EMS	pseudouridine synthase
HLK68_01400	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HLK68_01410	ENOG4105MIX	Adenylate cyclase
HLK68_01425	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HLK68_01430	ENOG4108JQ7	(ABC) transporter
HLK68_01440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK68_01445	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK68_01460	ENOG4105BZ1	(ABC) transporter
HLK68_01465	ENOG4105BZ1	(ABC) transporter
HLK68_01475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLK68_01480	ENOG4108KP7	hydrolase
HLK68_01485	ENOG4105C8T	Leucyl-tRNA synthetase
HLK68_01490	ENOG4105N5T	Radical SAM Protein
HLK68_01520	ENOG4105CP7	Triose-phosphate isomerase
HLK68_01525	ENOG4105ESV	Glycosyl transferase, family 4
HLK68_01530	ENOG4105CQZ	Histidine kinase
HLK68_01535	ENOG4105E1K	spore germination protein
HLK68_01575	ENOG4105CJZ	response regulator
HLK68_01580	ENOG4105E5G	Alpha beta hydrolase fold
HLK68_01600	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK68_01615	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HLK68_01620	ENOG4107S6Z	Na H antiporter
HLK68_01655	ENOG4105E1K	spore germination protein
HLK68_01660	ENOG4105CMQ	Chloride channel
HLK68_01685	ENOG4105D3R	alkyl hydroperoxide reductase
HLK68_01730	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLK68_01795	ENOG4107T8Q	Glycosyl transferase (Group 1
HLK68_01815	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
HLK68_01835	ENOG4108KMV	Glycosyl transferase (Group 1
HLK68_01840	ENOG41068W6	Capsular polysaccharide biosynthesis protein
HLK68_01845	ENOG4107SJB	teichoic acid biosynthesis
HLK68_01850	ENOG4105CG5	Glycosyl transferase (Group 1
HLK68_01865	ENOG4105D3Q	Sugar transferase
HLK68_01870	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HLK68_01880	ENOG4107YJ4	chain length determinant protein
HLK68_01895	ENOG4105DIN	metallophosphoesterase
HLK68_01900	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLK68_01905	ENOG4108KGH	TRANSCRIPTIONal
HLK68_01935	ENOG4105D3Q	Sugar transferase
HLK68_01940	ENOG4107YJ4	chain length determinant protein
HLK68_01950	ENOG4105BZ1	(ABC) transporter
HLK68_02005	ENOG4105D3Q	Sugar transferase
HLK68_02010	ENOG4107YJ4	chain length determinant protein
HLK68_02035	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HLK68_02065	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLK68_02080	ENOG4105DY9	regulatoR
HLK68_02085	ENOG4105BZU	Histidine kinase
HLK68_02105	ENOG4105KIS	phospholipid-binding protein
HLK68_02115	ENOG4105DWF	phosphomethylpyrimidine kinase
HLK68_02120	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HLK68_02125	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HLK68_02135	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HLK68_02140	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HLK68_02145	ENOG4105DM4	PTS System
HLK68_02150	ENOG4105DM4	PTS System
HLK68_02175	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HLK68_02185	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HLK68_02195	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HLK68_02220	ENOG4105CC5	ABC transporter
HLK68_02225	ENOG4105DIK	(ABC) transporter
HLK68_02230	ENOG4105CC5	ABC transporter
HLK68_02235	ENOG4105DIK	(ABC) transporter
HLK68_02240	ENOG4105DSE	periplasmic solute binding protein
HLK68_02255	ENOG4108Q3X	Transcriptional regulator
HLK68_02260	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK68_02275	ENOG4105C0A	alcohol dehydrogenase
HLK68_02285	ENOG4107414	GntR family transcriptional regulator
HLK68_02290	ENOG4105CG3	alpha amylase, catalytic region
HLK68_02295	ENOG4105C5Y	PTS System
HLK68_02315	ENOG4105FTV	AraC Family Transcriptional Regulator
HLK68_02320	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HLK68_02340	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HLK68_02350	ENOG4105CIG	ABC transporter
HLK68_02375	ENOG4107RBB	ABC transporter, permease
HLK68_02380	ENOG4105C19	ABC transporter
HLK68_02390	ENOG4108X4Q	Hydrolase
HLK68_02395	ENOG4105E98	transcriptional regulator DeoR family
HLK68_02405	ENOG4105C2F	Histidine kinase
HLK68_02410	ENOG4105EQD	regulatoR
HLK68_02430	ENOG4105F9F	transposase
HLK68_02435	ENOG4105C4C	beta-galactosidase
HLK68_02440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HLK68_02450	ENOG4105C37	(CBS) domain
HLK68_02465	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HLK68_02470	ENOG4107R33	ppx gppa phosphatase
HLK68_02490	ENOG4105CV8	reductase
HLK68_02510	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HLK68_02515	ENOG4105CPN	adenine deaminase
HLK68_02520	ENOG4107RUE	extracellular solute-binding protein family 1
HLK68_02525	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK68_02530	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
HLK68_02535	ENOG4105F38	ABC transporter, permease
HLK68_02540	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLK68_02560	ENOG4107R4J	Chloride channel
HLK68_02565	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLK68_02575	ENOG4105DKQ	ROK family
HLK68_02580	ENOG41066F8	ROK family
HLK68_02600	ENOG4105C8I	hydrolase, family 38
HLK68_02610	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK68_02625	ENOG4105C2F	Histidine kinase
HLK68_02635	ENOG4105DG6	mannose-6-phosphate isomerase
HLK68_02640	ENOG4105CS2	ec 3.2.1.21
HLK68_02650	ENOG4105C19	ABC transporter
HLK68_02655	ENOG4105EWM	Histidine kinase
HLK68_02660	ENOG4105CJZ	response regulator
HLK68_02680	ENOG4105EPR	degv family
HLK68_02685	ENOG4108ZJ4	polysaccharide deacetylase
HLK68_02700	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HLK68_02705	ENOG4107YHD	transcriptional regulator
HLK68_02715	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HLK68_02735	ENOG4105CDA	abc transporter atp-binding protein
HLK68_02740	ENOG4105DSP	amino acid AbC transporter
HLK68_02745	ENOG4105E5Q	amino acid AbC transporter
HLK68_02765	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HLK68_02775	ENOG4105EJQ	L-serine dehydratase
HLK68_02780	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HLK68_02785	ENOG4105CN1	protease
HLK68_02795	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HLK68_02800	ENOG4105CAK	Cell division ATP-binding protein ftsE
HLK68_02805	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HLK68_02810	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HLK68_02820	ENOG4105MS2	ribosomal subunit Interface protein
HLK68_02835	ENOG4105DE4	1-phosphofructokinase
HLK68_02860	ENOG4105EPR	degv family
HLK68_02865	ENOG4105EPR	degv family
HLK68_02870	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HLK68_02875	ENOG4105D1H	recombination factor protein RarA
HLK68_02880	ENOG4105DFF	Rod shape-determining protein mreb
HLK68_02900	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HLK68_02905	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HLK68_02915	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HLK68_02925	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HLK68_02930	ENOG41085E0	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HLK68_02935	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
HLK68_02950	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HLK68_02955	ENOG4108YZG	isomerase
HLK68_02970	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLK68_02975	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HLK68_02980	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HLK68_02985	ENOG4105CDU	Replicative dna helicase
HLK68_02990	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HLK68_02995	ENOG4105BZR	domain protein
HLK68_03015	ENOG4108UUM	single-stranded DNA-binding protein
HLK68_03030	ENOG4105S7S	phosphonate abc transporter
HLK68_03035	ENOG4105D5T	phosphonate abc transporter
HLK68_03045	ENOG4105C3G	gtp-binding protein
HLK68_03055	ENOG4107QZ7	Cellulose synthase catalytic subunit
HLK68_03065	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLK68_03080	ENOG4106A3R	peptidase
HLK68_03085	ENOG4105CZX	twitching motility protein
HLK68_03130	ENOG4105D7Q	type ii secretion system
HLK68_03135	ENOG4107QHF	type ii secretion system protein e
HLK68_03145	ENOG4105BZ4	penicillin-binding protein
HLK68_03160	ENOG4105C0H	protease
HLK68_03165	ENOG4105F8V	Hydrolase, tatD family
HLK68_03170	ENOG4108JQ7	(ABC) transporter
HLK68_03180	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK68_03185	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK68_03190	ENOG4108J59	Extracellular solute-binding protein, family 5
HLK68_03210	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HLK68_03215	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HLK68_03225	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK68_03230	ENOG41060K3	Methyltransferase
HLK68_03235	ENOG4105MA4	psp1 domain protein
HLK68_03240	ENOG4105FA2	dna polymerase iii
HLK68_03245	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HLK68_03260	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HLK68_03265	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HLK68_03270	ENOG4108JJB	ABC transporter
HLK68_03275	ENOG4108JJB	ABC transporter
HLK68_03285	ENOG4105BZ1	(ABC) transporter
HLK68_03290	ENOG4105D3R	alkyl hydroperoxide reductase
HLK68_03420	ENOG4108UJD	30S ribosomal protein S9
HLK68_03435	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HLK68_03440	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HLK68_03445	ENOG4105C6E	dna polymerase iii
HLK68_03450	ENOG4107QJQ	Mate efflux family protein
HLK68_03460	ENOG4105VUF	Transcriptional regulator
HLK68_03465	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HLK68_03475	ENOG4105E2Z	phosphate ABC transporter (Permease
HLK68_03480	ENOG4105C8U	phosphate abc transporter
HLK68_03485	ENOG4107S17	Phosphate-binding protein
HLK68_03490	ENOG4105BZU	Histidine kinase
HLK68_03495	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK68_03505	ENOG4108Z6B	deaminase
HLK68_03520	ENOG4105ZMH	deoxynucleoside kinase
HLK68_03535	ENOG4105CE1	Ferrous iron transport protein b
HLK68_03550	ENOG4107104	thymidine kinase
HLK68_03555	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HLK68_03560	ENOG4105CH2	amidohydrolase
HLK68_03565	ENOG4105BZU	Histidine kinase
HLK68_03590	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HLK68_03595	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HLK68_03600	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HLK68_03605	ENOG4107TXC	Transcriptional regulator
HLK68_03610	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HLK68_03620	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HLK68_03625	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLK68_03640	ENOG4105C6K	Malic enzyme
HLK68_03650	ENOG4108RE9	Phosphodiesterase
HLK68_03670	ENOG4105C5F	glutamine synthetase
HLK68_03680	ENOG4105CHR	reductase
HLK68_03690	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HLK68_03695	ENOG4105KVH	Transcriptional regulator
HLK68_03730	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HLK68_03740	ENOG4105CD3	dihydroorotase
HLK68_03770	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLK68_03775	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLK68_03780	ENOG4105TMB	Formate nitrite transporter
HLK68_03790	ENOG4105CNW	domain protein
HLK68_03795	ENOG4105C0A	alcohol dehydrogenase
HLK68_03800	ENOG4107RVG	penicillin-binding protein
HLK68_03810	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HLK68_03825	ENOG4105C7N	Xanthine uracil vitamin C permease
HLK68_03840	ENOG4105DER	m42 family
HLK68_03845	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLK68_03880	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLK68_03890	ENOG4105EEI	dihydropteroate synthase
HLK68_03895	ENOG4108RAC	Rubrerythrin
HLK68_03905	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLK68_03940	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HLK68_03970	ENOG4108IPW	abc transporter atp-binding protein
HLK68_03975	ENOG4105CM4	permease protein
HLK68_03980	ENOG4105DHS	permease protein
HLK68_03985	ENOG4105ID8	Transcriptional regulator, ARAC family
HLK68_04005	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HLK68_04010	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HLK68_04015	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HLK68_04025	ENOG4105G3A	stage ii sporulation protein e
HLK68_04030	ENOG4105UQX	Mate efflux family protein
HLK68_04035	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HLK68_04040	ENOG4105DA5	(ABC) transporter
HLK68_04050	ENOG41060GV	RNA binding s1 domain protein
HLK68_04065	ENOG4105VYY	sporulation protein yabp
HLK68_04080	ENOG41082I2	s4 domain protein
HLK68_04085	ENOG4108IY2	MazG family
HLK68_04105	ENOG4105KNA	-acetyltransferase
HLK68_04115	ENOG4105BZ1	(ABC) transporter
HLK68_04125	ENOG4105K56	Transcriptional regulator
HLK68_04130	ENOG4105DWD	nucleoside recognition domain protein
HLK68_04135	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLK68_04160	ENOG4108VXD	carboxy-peptidase
HLK68_04185	ENOG4105DQ6	Transposase
HLK68_04240	ENOG4105C5R	Aminotransferase
HLK68_04245	ENOG4105C12	Phosphoribosylglycinamide synthetase
HLK68_04250	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HLK68_04255	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HLK68_04260	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HLK68_04270	ENOG4105C8V	SAICAR synthetase
HLK68_04280	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HLK68_04285	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HLK68_04295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLK68_04300	ENOG4108M14	stage v sporulation protein t
HLK68_04305	ENOG4108JA2	transcriptioN-repair coupling factor
HLK68_04310	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HLK68_04315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLK68_04320	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HLK68_04325	ENOG4105K4W	Could be involved in septation (By similarity)
HLK68_04330	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HLK68_04335	ENOG4105W42	Veg protein
HLK68_04340	ENOG4105XFA	sporulation peptidase YabG
HLK68_04345	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HLK68_04355	ENOG4105DCI	Phosphohydrolase
HLK68_04370	ENOG4108IJ2	phosphate acetyltransferase
HLK68_04375	ENOG4108VKI	Cell wall hydrolase
HLK68_04385	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HLK68_04400	ENOG4105K59	histidine triad (HIT) protein
HLK68_04410	ENOG4105EAH	synthase
HLK68_04415	ENOG410667J	hydrolase
HLK68_04420	ENOG4108RAC	Rubrerythrin
HLK68_04425	ENOG4108RAC	Rubrerythrin
HLK68_04430	ENOG4105F1A	Pyruvate formate-lyase
HLK68_04445	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK68_04450	ENOG4108UMI	ABC transporter, permease
HLK68_04455	ENOG4105D01	(LipO)protein
HLK68_04460	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HLK68_04480	ENOG4107QI1	Mate efflux family protein
HLK68_04495	ENOG4105WEF	catalase
HLK68_04500	ENOG4105CHH	sulfate transporter
HLK68_04505	ENOG4105C1J	atp-dependent rna helicase
HLK68_04510	ENOG4105C5H	ABC transporter
HLK68_04545	ENOG4108115	UPF0145 protein
HLK68_04560	ENOG4105KVH	Transcriptional regulator
HLK68_04585	ENOG4108AEY	RNA polymerase sigma factor
HLK68_04595	ENOG4105CDY	transcriptional regulatory protein
HLK68_04640	ENOG4108KD5	ADP-ribosylation crystallin J1
HLK68_04645	ENOG4108TFM	Kinase, PfkB family
HLK68_04650	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
HLK68_04655	ENOG4105DG6	mannose-6-phosphate isomerase
HLK68_04660	ENOG4105VCP	PTS System
HLK68_04665	ENOG41066F8	ROK family
HLK68_04670	ENOG4105CS2	ec 3.2.1.21
HLK68_04675	ENOG4105CK1	PTS System
HLK68_04680	ENOG4105VZJ	PTS System
HLK68_04685	ENOG4105DKQ	ROK family
HLK68_04690	ENOG4108S3Y	transcriptional regulator
HLK68_04695	ENOG4108VXD	carboxy-peptidase
HLK68_04700	ENOG4105EMN	RNA polymerase sigma factor
HLK68_04725	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLK68_04740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK68_04745	ENOG4105C2I	pirin domain protein
HLK68_04750	ENOG4105CFC	Transporter
HLK68_04765	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLK68_04785	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HLK68_04790	ENOG4105CGH	5'-nucleotidase
HLK68_04810	ENOG41090E6	transcriptional regulator MERR family
HLK68_04830	ENOG4107UWA	esterase
HLK68_04855	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLK68_04875	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLK68_04885	ENOG4105BZU	Histidine kinase
HLK68_04890	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HLK68_04910	ENOG4105FCD	Major Facilitator
HLK68_04935	ENOG4105DDN	Pentapeptide repeat-containing protein
HLK68_04950	ENOG4105D6U	Sodium Glutamate Symporter
HLK68_04955	ENOG4108X4Q	Hydrolase
HLK68_04975	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK68_04990	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HLK68_05015	ENOG4105Q2H	domain protein
HLK68_05020	ENOG4105DR5	peptidase
HLK68_05025	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HLK68_05030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLK68_05035	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLK68_05040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLK68_05045	ENOG410848D	S4 domain protein YaaA
HLK68_05050	ENOG4105VDK	protein, conserved in bacteria
HLK68_05055	ENOG4105D8X	mechanosensitive ion channel
HLK68_05060	ENOG4105FA0	parb-like partition protein
HLK68_05065	ENOG4107QJE	Chromosome Partitioning Protein
HLK68_05070	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HLK68_05075	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HLK68_05085	ENOG4108IUX	(ABC) transporter
HLK68_05090	ENOG4105RHA	ABC transporter, permease
HLK68_05095	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLK68_05105	ENOG4105VG0	50S ribosomal protein l34
HLK68_05120	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HLK68_05130	ENOG4105CU9	asparagine synthetase A
HLK68_05135	ENOG4105C5S	asparaginyl-tRNA synthetase
HLK68_05160	ENOG4108IUM	Glycogen debranching enzyme
HLK68_05165	ENOG4105BZU	Histidine kinase
HLK68_05175	ENOG4105C75	arginyL-tRNA synthetase
HLK68_05205	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HLK68_05215	ENOG4105BZU	Histidine kinase
HLK68_05220	ENOG4105DZ0	fad dependent oxidoreductase
HLK68_05245	ENOG4105F3H	Histidine kinase
HLK68_05250	ENOG4105C83	adenylosuccinate lyase
HLK68_05255	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HLK68_05260	ENOG41067QW	Transcriptional regulator
HLK68_05265	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HLK68_05270	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HLK68_05310	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HLK68_05320	ENOG4105CG3	alpha amylase, catalytic region
HLK68_05330	ENOG41081HM	2'-5' rna ligase
HLK68_05355	ENOG4105BZU	Histidine kinase
HLK68_05365	ENOG4105EMN	RNA polymerase sigma factor
HLK68_05375	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLK68_05380	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HLK68_05395	ENOG4107RWR	Sodium hydrogen exchanger
HLK68_05405	ENOG4105CBT	Fructose-1,6-bisphosphatase
HLK68_05410	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HLK68_05420	ENOG4105K7K	Transcriptional regulator
HLK68_05435	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HLK68_05440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HLK68_05455	ENOG4105KME	endoribonuclease L-psp
HLK68_05460	ENOG4105C7B	Threonine dehydratase
HLK68_05465	ENOG4105C8N	cysteinyl-tRNA synthetase
HLK68_05470	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLK68_05475	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HLK68_05485	ENOG4107FGU	50S ribosomal protein L33
HLK68_05490	ENOG410683Z	Preprotein translocase SecE subunit
HLK68_05495	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HLK68_05500	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HLK68_05505	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HLK68_05510	ENOG4108VZM	50s ribosomal protein L10
HLK68_05515	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HLK68_05520	ENOG4107Y49	methyltransferase
HLK68_05525	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK68_05530	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK68_05535	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HLK68_05540	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HLK68_05550	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HLK68_05560	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HLK68_05565	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HLK68_05570	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HLK68_05575	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLK68_05580	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HLK68_05585	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HLK68_05590	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HLK68_05595	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HLK68_05600	ENOG41082SA	50s ribosomal protein l29
HLK68_05610	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HLK68_05620	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLK68_05625	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HLK68_05630	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HLK68_05640	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HLK68_05645	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HLK68_05650	ENOG4105VPB	50S ribosomal protein L30
HLK68_05660	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HLK68_05665	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HLK68_05670	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLK68_05680	ENOG41067V7	50S ribosomal protein L36
HLK68_05685	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLK68_05690	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HLK68_05695	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK68_05705	ENOG4105C8B	TIGR00159 family
HLK68_05715	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HLK68_05720	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLK68_05725	ENOG41067TZ	transcriptional regulator, MarR family
HLK68_05750	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_05765	ENOG4105EJV	Membrane
HLK68_05775	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HLK68_05790	ENOG4105CPF	Cell wall formation (By similarity)
HLK68_05795	ENOG4108X4Q	Hydrolase
HLK68_05800	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLK68_05810	ENOG4105CEV	competence damage-inducible protein
HLK68_05820	ENOG4105CP7	Triose-phosphate isomerase
HLK68_05830	ENOG4105CN5	Metallo-Beta-Lactamase
HLK68_05835	ENOG4106AKJ	
HLK68_05870	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HLK68_05875	ENOG4105F9F	transposase
HLK68_05885	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
HLK68_05890	ENOG4105VEQ	Cold shock protein
HLK68_05920	ENOG4108X4Q	Hydrolase
HLK68_05935	ENOG4105C5Y	PTS System
HLK68_05945	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HLK68_05950	ENOG4105CJW	magnesium transporter
HLK68_05955	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HLK68_05960	ENOG4105GR3	Histidine kinase
HLK68_05980	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HLK68_05985	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HLK68_05995	ENOG4105DZ1	carboxypeptidase
HLK68_06005	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HLK68_06025	ENOG4105DU0	nucleoside hydrolase
HLK68_06040	ENOG4105ST3	Transcriptional regulator
HLK68_06045	ENOG4108RCM	Nitroreductase
HLK68_06070	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_06085	ENOG4105F44	Two component transcriptional regulator, winged helix family
HLK68_06090	ENOG4106F60	Histidine kinase
HLK68_06095	ENOG4108RAC	Rubrerythrin
HLK68_06120	ENOG41076HS	cation diffusion facilitator family transporter
HLK68_06130	ENOG4105E66	phosphoriboisomerase A
HLK68_06140	ENOG4106KNT	transcriptional regulator
HLK68_06165	ENOG4105CZV	ABC transporter
HLK68_06170	ENOG4105ZMH	deoxynucleoside kinase
HLK68_06175	ENOG4105EKQ	RNA-directed DNA polymerase
HLK68_06195	ENOG4105VMP	Transcriptional regulator
HLK68_06205	ENOG4105K63	Thioredoxin
HLK68_06230	ENOG41067QW	Transcriptional regulator
HLK68_06240	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HLK68_06255	ENOG4105CPC	Aldo Keto reductase
HLK68_06265	ENOG4105F44	Two component transcriptional regulator, winged helix family
HLK68_06270	ENOG4105GR3	Histidine kinase
HLK68_06280	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_06290	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_06300	ENOG41076CZ	activating enzyme
HLK68_06305	ENOG4105G0K	glycine radical enzyme YjjI family
HLK68_06315	ENOG4105C8J	)-transporter
HLK68_06350	ENOG4105CE4	GlcNAc 6-P deacetylase
HLK68_06370	ENOG4106N3A	copper homeostasis protein cutc
HLK68_06385	ENOG4105II7	pyrroline-5-carboxylate reductase
HLK68_06390	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HLK68_06395	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HLK68_06400	ENOG4105C02	permease
HLK68_06410	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HLK68_06420	ENOG4108UB7	
HLK68_06430	ENOG4108QCI	YvbH-like oligomerisation region
HLK68_06450	ENOG4105EA8	2-Nitropropane dioxygenase
HLK68_06455	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HLK68_06460	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLK68_06465	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HLK68_06470	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HLK68_06480	ENOG4105EA8	2-Nitropropane dioxygenase
HLK68_06485	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLK68_06490	ENOG4105CHR	reductase
HLK68_06495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLK68_06510	ENOG4108W76	histidinol phosphate phosphatase hisj family
HLK68_06515	ENOG4105FAA	peptidase M23
HLK68_06585	ENOG4105K8N	protein family UPF0079, ATPase
HLK68_06590	ENOG41072GX	Peptidase M22 Glycoprotease
HLK68_06600	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLK68_06610	ENOG4105C5H	ABC transporter
HLK68_06615	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HLK68_06625	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HLK68_06635	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HLK68_06640	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HLK68_06645	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HLK68_06650	ENOG4105WG9	Conserved Protein
HLK68_06655	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
HLK68_06665	ENOG4108STX	response regulator
HLK68_06670	ENOG4105BZU	Histidine kinase
HLK68_06675	ENOG4105CHM	Aminotransferase
HLK68_06680	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HLK68_06690	ENOG410691R	Modulates RecA activity (By similarity)
HLK68_06695	ENOG4105FDP	GntR family transcriptional regulator
HLK68_06710	ENOG4105CG3	alpha amylase, catalytic region
HLK68_06715	ENOG4105DR5	peptidase
HLK68_06720	ENOG4108JU6	CBS domain protein
HLK68_06730	ENOG4105CKK	Glycosyl transferase, family 2
HLK68_06740	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HLK68_06745	ENOG4105CBD	Diacylglycerol kinase
HLK68_06750	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
HLK68_06775	ENOG4105F9F	transposase
HLK68_06790	ENOG4105TWJ	Domain of unknown function (DUF1919)
HLK68_06795	ENOG4105CND	Glycosyl transferase, family 2
HLK68_06805	ENOG4105CMR	udp-glucose 4-epimerase
HLK68_06875	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
HLK68_06890	ENOG4105CX6	glutaminyL-tRNA synthetase
HLK68_06895	ENOG4105C4R	Atp-dependent dna helicase
HLK68_06900	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HLK68_06915	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLK68_06925	ENOG41086DT	Membrane protein of unknown function
HLK68_06935	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HLK68_06940	ENOG4107XGZ	Hydrolase
HLK68_06945	ENOG4105C3M	thioredoxin reductase
HLK68_06965	ENOG4105CHW	UPF0052 protein
HLK68_06970	ENOG4105CIE	May be required for sporulation (By similarity)
HLK68_06975	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLK68_06985	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HLK68_06990	ENOG4105C02	permease
HLK68_06995	ENOG4105FEU	K -dependent Na -Ca exchanger
HLK68_07005	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HLK68_07010	ENOG4105PNM	synthesis protein
HLK68_07015	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HLK68_07020	ENOG4105EWK	phytoene
HLK68_07035	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLK68_07050	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HLK68_07060	ENOG4105D2X	ABC transporter substrate-binding protein
HLK68_07065	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK68_07070	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK68_07075	ENOG4105DRS	transport system, permease
HLK68_07080	ENOG4108IJG	ABC transporter substrate-binding protein
HLK68_07085	ENOG4105SFS	phosphoesterase RecJ domain protein
HLK68_07090	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HLK68_07095	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLK68_07105	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK68_07110	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HLK68_07120	ENOG4105WZW	rhodanese family
HLK68_07140	ENOG4108UT2	hemolysin iii
HLK68_07150	ENOG4105CEM	UPF0597 protein
HLK68_07155	ENOG4105DZ6	Band 7 protein
HLK68_07170	ENOG4105C02	permease
HLK68_07185	ENOG4105C59	p-type ATPase
HLK68_07195	ENOG4105BZU	Histidine kinase
HLK68_07205	ENOG4108RVA	ribokinase
HLK68_07215	ENOG4105DND	Transcriptional regulator
HLK68_07220	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HLK68_07235	ENOG4105EWK	phytoene
HLK68_07245	ENOG4107QMU	Mate efflux family protein
HLK68_07255	ENOG4105BZU	Histidine kinase
HLK68_07275	ENOG410681U	heavy metal transport detoxification protein
HLK68_07290	ENOG4105C19	ABC transporter
HLK68_07305	ENOG4105CJ1	ABC, transporter
HLK68_07325	ENOG4105BZU	Histidine kinase
HLK68_07330	ENOG4105CID	antiterminator
HLK68_07340	ENOG4105C5Y	PTS System
HLK68_07345	ENOG4105CS2	ec 3.2.1.21
HLK68_07370	ENOG4107R73	Mate efflux family protein
HLK68_07375	ENOG4105VEQ	Cold shock protein
HLK68_07380	ENOG4107Y2X	deaminase
HLK68_07400	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HLK68_07405	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLK68_07425	ENOG4105DNP	FAD linked oxidase domain protein
HLK68_07435	ENOG4105MAX	Superoxide reductase
HLK68_07450	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HLK68_07465	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
HLK68_07475	ENOG4105DQ5	transport system permease protein
HLK68_07480	ENOG4105E0A	ABC, transporter
HLK68_07505	ENOG4108R6W	Transcriptional regulator, ARAC family
HLK68_07525	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_07545	ENOG4108YYD	acetyltransferase
HLK68_07560	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HLK68_07580	ENOG4107EFR	Flavocytochrome c
HLK68_07595	ENOG4105D9P	serine threonine protein kinase
HLK68_07605	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HLK68_07610	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HLK68_07620	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HLK68_07640	ENOG4107QZB	decarboxylase
HLK68_07660	ENOG4105EHG	Permease protein
HLK68_07665	ENOG4105E0A	ABC, transporter
HLK68_07690	ENOG4105KT7	mgtC SapB transporter
HLK68_07700	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HLK68_07705	ENOG4105CFI	type iii restriction protein res subunit
HLK68_07710	ENOG4105M6F	mutator MutT protein
HLK68_07755	ENOG4105D0C	transport protein
HLK68_07760	ENOG4107QIV	Cytochrome c biogenesis protein
HLK68_07775	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HLK68_07780	ENOG4105DQ5	transport system permease protein
HLK68_07785	ENOG4105EHG	Permease protein
HLK68_07790	ENOG4105E0A	ABC, transporter
HLK68_07795	ENOG4107Y80	Major Facilitator superfamily
HLK68_07810	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HLK68_07815	ENOG4105CFH	Aspartokinase
HLK68_07820	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HLK68_07825	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK68_07830	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HLK68_07835	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HLK68_07840	ENOG4105VUF	Transcriptional regulator
HLK68_07850	ENOG4105C2X	Arabinose 5-phosphate isomerase
HLK68_07860	ENOG4105CS2	ec 3.2.1.21
HLK68_07880	ENOG4105HMI	Membrane
HLK68_07890	ENOG4105BZU	Histidine kinase
HLK68_07910	ENOG4105W5Q	DNA repair protein (RadC
HLK68_07915	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
HLK68_07940	ENOG410826E	Dna repair protein radc
HLK68_07970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_07995	ENOG4105W5Q	DNA repair protein (RadC
HLK68_08080	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HLK68_08090	ENOG4108F3G	Type I restriction-modification system, R subunit
HLK68_08095	ENOG4105W5Q	DNA repair protein (RadC
HLK68_08125	ENOG4105DZR	Type I site-specific deoxyribonuclease
HLK68_08140	ENOG4105W5Q	DNA repair protein (RadC
HLK68_08230	ENOG4105C5Q	Transcriptional regulator
HLK68_08245	ENOG4105CBC	glutamate synthase
HLK68_08265	ENOG4105F6S	Spore photoproduct lyase
HLK68_08275	ENOG4108KGH	TRANSCRIPTIONal
HLK68_08280	ENOG4105CFP	Peptidase U32
HLK68_08285	ENOG4108QG2	Membrane
HLK68_08290	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HLK68_08300	ENOG4105YWU	small acid-soluble spore protein
HLK68_08305	ENOG4105YWU	small acid-soluble spore protein
HLK68_08310	ENOG4105YWU	small acid-soluble spore protein
HLK68_08315	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HLK68_08325	ENOG4105EVI	UPF0374 protein
HLK68_08420	ENOG4105CG3	alpha amylase, catalytic region
HLK68_08435	ENOG4105F9F	transposase
HLK68_08445	ENOG4105EG2	ABC transporter, permease
HLK68_08450	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HLK68_08460	ENOG41067QW	Transcriptional regulator
HLK68_08540	ENOG4107QJE	Chromosome Partitioning Protein
HLK68_08555	ENOG4108UW5	maltose o-acetyltransferase
HLK68_08575	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK68_08590	ENOG41067QW	Transcriptional regulator
HLK68_08595	ENOG41069JR	
HLK68_08600	ENOG4105DA5	(ABC) transporter
HLK68_08615	ENOG4105ETE	Transcriptional regulator (LacI family
HLK68_08620	ENOG4105C5Y	PTS System
HLK68_08660	ENOG4108R6W	Transcriptional regulator, ARAC family
HLK68_08670	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK68_08675	ENOG4105DRS	transport system, permease
HLK68_08695	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLK68_08710	ENOG4105CNT	hydrolase family 2
HLK68_08715	ENOG4105CNT	hydrolase family 2
HLK68_08720	ENOG4105KRI	phosphocarrier protein (HPr
HLK68_08735	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HLK68_08745	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HLK68_08750	ENOG4105CQ4	Transcriptional regulator
HLK68_08755	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HLK68_08760	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HLK68_08765	ENOG4105CMR	udp-glucose 4-epimerase
HLK68_08780	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HLK68_08820	ENOG4107RAQ	aminopeptidase
HLK68_08840	ENOG4105EAM	Na Pi-cotransporter
HLK68_08845	ENOG4105C3K	feS assembly ATPase SufC
HLK68_08850	ENOG4105JRK	feS assembly protein SufD
HLK68_08855	ENOG4105C9B	Cysteine desulfurase
HLK68_08860	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HLK68_08865	ENOG4105DIW	FeS assembly protein SUFB
HLK68_08875	ENOG41080XQ	Signal transduction protein with cbs domains
HLK68_08880	ENOG4105KZD	Domain of unknown function (DUF1805)
HLK68_08890	ENOG4105C19	ABC transporter
HLK68_08895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK68_08910	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HLK68_08915	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLK68_08940	ENOG4108P49	AntiSigma factor
HLK68_08945	ENOG4105JVQ	RNA Polymerase
HLK68_08950	ENOG4108P49	AntiSigma factor
HLK68_08960	ENOG4105C4X	radical SAM domain protein
HLK68_08975	ENOG4105CFI	type iii restriction protein res subunit
HLK68_09000	ENOG4105DB7	PHP domain protein
HLK68_09010	ENOG4108RAC	Rubrerythrin
HLK68_09025	ENOG4108ETY	sodium dicarboxylate symporter
HLK68_09035	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HLK68_09065	ENOG4108NRW	Phospholipase, patatin family
HLK68_09075	ENOG4107YDN	peptide deformylase
HLK68_09080	ENOG4108KYE	ABC-2 type transporter
HLK68_09090	ENOG4105CJ1	ABC, transporter
HLK68_09095	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK68_09100	ENOG4105BZU	Histidine kinase
HLK68_09125	ENOG4105C4R	Atp-dependent dna helicase
HLK68_09145	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK68_09150	ENOG4108UMI	ABC transporter, permease
HLK68_09155	ENOG4105D01	(LipO)protein
HLK68_09175	ENOG4105D0C	transport protein
HLK68_09180	ENOG4105NBF	ammecr1 domain protein
HLK68_09205	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
HLK68_09210	ENOG4105CH2	amidohydrolase
HLK68_09230	ENOG4105C5Y	PTS System
HLK68_09250	ENOG4105CAH	Chromate
HLK68_09255	ENOG4105F9F	transposase
HLK68_09260	ENOG4105C1J	atp-dependent rna helicase
HLK68_09265	ENOG4105BZU	Histidine kinase
HLK68_09270	ENOG4105C1J	atp-dependent rna helicase
HLK68_09275	ENOG4108VW9	Membrane
HLK68_09280	ENOG4108IUM	Glycogen debranching enzyme
HLK68_09290	ENOG4105D4P	Coproporphyrinogen iii oxidase
HLK68_09295	ENOG4105EQI	Metal Dependent Phosphohydrolase
HLK68_09300	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HLK68_09320	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
HLK68_09335	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
HLK68_09360	ENOG4107QIZ	NADH dehydrogenase
HLK68_09365	ENOG4107QHI	-hydrogenase
HLK68_09375	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HLK68_09380	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLK68_09385	ENOG4105EUJ	GTP cyclohydrolase i
HLK68_09390	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HLK68_09395	ENOG4105D49	3-dehydroquinate synthase
HLK68_09400	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HLK68_09405	ENOG41068YB	TPR repeat-containing protein
HLK68_09415	ENOG4108JYZ	YitT family
HLK68_09425	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLK68_09440	ENOG4105CSM	endonuclease III
HLK68_09445	ENOG4105BZ4	penicillin-binding protein
HLK68_09465	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HLK68_09475	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HLK68_09480	ENOG4105D48	metallophosphoesterase
HLK68_09485	ENOG4105MCT	stage V sporulation protein S
HLK68_09490	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLK68_09510	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HLK68_09515	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HLK68_09520	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLK68_09530	ENOG4105VPS	UPF0291 protein
HLK68_09550	ENOG4105VXM	UPF0154 protein
HLK68_09560	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLK68_09565	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLK68_09585	ENOG4105C9A	Phoh family
HLK68_09590	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HLK68_09595	ENOG4107YR5	Diacylglycerol kinase
HLK68_09600	ENOG4105KG3	cytidine deaminase
HLK68_09605	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HLK68_09615	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
HLK68_09620	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HLK68_09625	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HLK68_09630	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_09640	ENOG4105EGD	dinuclear metal center protein, YbgI family
HLK68_09645	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HLK68_09650	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HLK68_09655	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HLK68_09660	ENOG4105ETE	Transcriptional regulator (LacI family
HLK68_09670	ENOG4105ID8	Transcriptional regulator, ARAC family
HLK68_09685	ENOG4105DUM	transcriptional regulator, lysR family
HLK68_09710	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HLK68_09715	ENOG4105C0A	alcohol dehydrogenase
HLK68_09725	ENOG4107WD8	ABC transporter, permease
HLK68_09730	ENOG4105YWU	small acid-soluble spore protein
HLK68_09750	ENOG4108RWN	rrna methyltransferase
HLK68_09755	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HLK68_09760	ENOG4105CHV	Transcription elongation factor NusA
HLK68_09765	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HLK68_09770	ENOG4105VHM	ribosomal protein
HLK68_09775	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HLK68_09780	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HLK68_09790	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HLK68_09795	ENOG4105PFC	Transcriptional regulator
HLK68_09810	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HLK68_09820	ENOG4105M59	Phosphodiesterase, mj0936 family
HLK68_09850	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLK68_09860	ENOG4105DUM	transcriptional regulator, lysR family
HLK68_09885	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HLK68_09890	ENOG4107ZYR	domain protein
HLK68_09930	ENOG4105PTM	secreted protein
HLK68_09970	ENOG4108X4Q	Hydrolase
HLK68_09980	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HLK68_10015	ENOG4105CNI	cell division protein FtsW
HLK68_10035	ENOG4105WUC	UPF0298 protein
HLK68_10040	ENOG4105K5M	30s ribosomal protein S16
HLK68_10045	ENOG4105VB6	UPF0109 protein
HLK68_10080	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HLK68_10085	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HLK68_10090	ENOG4107PPM	cobalt chelatase
HLK68_10105	ENOG4105D52	delta-aminolevulinic acid dehydratase
HLK68_10110	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLK68_10115	ENOG4105EAB	amino acid AbC transporter
HLK68_10120	ENOG4105E5Q	amino acid AbC transporter
HLK68_10125	ENOG4105CDA	abc transporter atp-binding protein
HLK68_10135	ENOG4105E70	isomerase
HLK68_10140	ENOG4105D2N	Aldolase
HLK68_10145	ENOG4105C2F	Histidine kinase
HLK68_10150	ENOG4105EQD	regulatoR
HLK68_10205	ENOG4105CT8	Phosphorylase
HLK68_10230	ENOG4105K56	Transcriptional regulator
HLK68_10235	ENOG4108V06	Glutathione peroxidase
HLK68_10265	ENOG4105BZ1	(ABC) transporter
HLK68_10285	ENOG4105J7I	hydrolase
HLK68_10335	ENOG4107QW3	Sucrose phosphorylase
HLK68_10350	ENOG4105BZW	Glycerate kinase
HLK68_10355	ENOG4107QQ0	gntp family
HLK68_10360	ENOG41087YS	Phage shock protein A
HLK68_10380	ENOG4106D6I	small acid-soluble spore protein
HLK68_10385	ENOG4108Z0R	Transferase
HLK68_10410	ENOG4105DB7	PHP domain protein
HLK68_10415	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HLK68_10420	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HLK68_10440	ENOG4105DFU	Cell wall formation (By similarity)
HLK68_10465	ENOG4105D1F	ATP-binding protein
HLK68_10470	ENOG4105CDE	UPF0348 protein
HLK68_10475	ENOG4105KNH	Nucleic acid-binding protein
HLK68_10480	ENOG41067VY	50S ribosomal protein L32
HLK68_10495	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HLK68_10500	ENOG4105C1J	atp-dependent rna helicase
HLK68_10505	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HLK68_10525	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HLK68_10535	ENOG4107RF6	penicillin-binding protein
HLK68_10550	ENOG4105DKQ	ROK family
HLK68_10555	ENOG4105C5X	domain protein
HLK68_10565	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HLK68_10625	ENOG4105DZ0	fad dependent oxidoreductase
HLK68_10630	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HLK68_10670	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLK68_10680	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLK68_10705	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HLK68_10710	ENOG4105DIB	Oligopeptide-binding protein
HLK68_10715	ENOG4105C5H	ABC transporter
HLK68_10730	ENOG4105DVT	helicase
HLK68_10735	ENOG41067TZ	transcriptional regulator, MarR family
HLK68_10740	ENOG4105BZ1	(ABC) transporter
HLK68_10745	ENOG4105BZ1	(ABC) transporter
HLK68_10750	ENOG4105D3Q	Sugar transferase
HLK68_10755	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HLK68_10765	ENOG4108YBP	pseudouridine synthase
HLK68_10805	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_10815	ENOG4105C2I	pirin domain protein
HLK68_10820	ENOG4105CMR	udp-glucose 4-epimerase
HLK68_10860	ENOG4107SC7	Inner membrane transporter yjeM
HLK68_10865	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HLK68_10870	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HLK68_10880	ENOG4108JJ9	ABC, transporter
HLK68_10885	ENOG4105BZ1	(ABC) transporter
HLK68_10890	ENOG4105VXR	cytoplasmic protein
HLK68_10895	ENOG4105WD1	Membrane
HLK68_10915	ENOG4105D5B	Sulfite reductase, subunit A
HLK68_10920	ENOG4107SHJ	sulfite reductase subunit b
HLK68_10925	ENOG410810Y	Sulfite reductase
HLK68_10930	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HLK68_10955	ENOG4107QW4	alcohol dehydrogenase
HLK68_10970	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLK68_10975	ENOG4105D1Q	UPF0246 protein
HLK68_11040	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HLK68_11055	ENOG4105C5H	ABC transporter
HLK68_11065	ENOG4108UW5	maltose o-acetyltransferase
HLK68_11080	ENOG4105VKD	bioY protein
HLK68_11105	ENOG4105C1J	atp-dependent rna helicase
HLK68_11115	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HLK68_11125	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HLK68_11130	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HLK68_11135	ENOG4105E0C	molybdate abc transporter
HLK68_11145	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLK68_11165	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HLK68_11180	ENOG4105FE9	pseudouridine synthase
HLK68_11200	ENOG4108W15	Protein of unknown function (DUF1456)
HLK68_11210	ENOG4105E0M	Sulfatase
HLK68_11250	ENOG4108UW5	maltose o-acetyltransferase
HLK68_11270	ENOG4108UW5	maltose o-acetyltransferase
HLK68_11275	ENOG410667J	hydrolase
HLK68_11280	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLK68_11285	ENOG4105C5W	Aldolase
HLK68_11300	ENOG4105HDK	L-asparaginase
HLK68_11320	ENOG4105BZ1	(ABC) transporter
HLK68_11325	ENOG4105D29	Helix-turn-helix type 11 domain protein
HLK68_11375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK68_11380	ENOG4105BZU	Histidine kinase
HLK68_11395	ENOG4105D44	asparaginase
HLK68_11425	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HLK68_11435	ENOG4105E98	transcriptional regulator DeoR family
HLK68_11440	ENOG4105DE4	1-phosphofructokinase
HLK68_11445	ENOG4105DM4	PTS System
HLK68_11470	ENOG4107R4J	Chloride channel
HLK68_11475	ENOG4105CGK	Exodeoxyribonuclease III
HLK68_11480	ENOG4105US7	Histidine kinase
HLK68_11485	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HLK68_11505	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
HLK68_11565	ENOG41082YX	Transcriptional regulator, arsr family
HLK68_11575	ENOG4105UQX	Mate efflux family protein
HLK68_11600	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HLK68_11605	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HLK68_11610	ENOG4105EUJ	GTP cyclohydrolase i
HLK68_11615	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HLK68_11620	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HLK68_11625	ENOG4105CTD	carboxy-peptidase
HLK68_11635	ENOG4108HCJ	Hydrolase
HLK68_11650	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HLK68_11675	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLK68_11690	ENOG4105DIB	Oligopeptide-binding protein
HLK68_11695	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK68_11700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK68_11705	ENOG4105C3U	ABC transporter
HLK68_11710	ENOG4108JQ7	(ABC) transporter
HLK68_11740	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HLK68_11745	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HLK68_11750	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HLK68_11755	ENOG4105CTB	Polyprenyl synthetase
HLK68_11760	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HLK68_11765	ENOG4105DX0	Hemolysin A
HLK68_11770	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HLK68_11775	ENOG4105S1Z	Stage IV sporulation protein B
HLK68_11780	ENOG4107QQR	Sporulation
HLK68_11785	ENOG4105F32	YngK protein
HLK68_11795	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLK68_11810	ENOG4105I3K	Ferric uptake regulator, Fur family
HLK68_11815	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK68_11825	ENOG4108Z3G	3H domain protein
HLK68_11835	ENOG4105DD7	kinase (PfkB family
HLK68_11845	ENOG4105CI1	PTS System
HLK68_11910	ENOG4108Z66	YbaK ebsC protein
HLK68_11915	ENOG410696E	Membrane
HLK68_11925	ENOG4107STQ	Multicopper oxidase
HLK68_11930	ENOG41082IR	Excinuclease ABC C subunit domain protein
HLK68_11940	ENOG4105QEK	Transcriptional regulator
HLK68_11950	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLK68_11955	ENOG4105DRS	transport system, permease
HLK68_11960	ENOG4105UQX	Mate efflux family protein
HLK68_11970	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HLK68_11985	ENOG4105CGH	5'-nucleotidase
HLK68_12010	ENOG4105DFD	Na H antiporter
HLK68_12015	ENOG4105VEQ	Cold shock protein
HLK68_12055	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLK68_12070	ENOG4105EPR	degv family
HLK68_12075	ENOG4107XJU	UPF0178 protein
HLK68_12080	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK68_12085	ENOG4108QEG	Membrane
HLK68_12100	ENOG4105W7A	Protein of unknown function (DUF503)
HLK68_12105	ENOG4105C02	permease
HLK68_12115	ENOG4105UQX	Mate efflux family protein
HLK68_12120	ENOG4108ZB6	transcriptional regulator AsnC family
HLK68_12125	ENOG4105CHM	Aminotransferase
HLK68_12140	ENOG4105EYW	Ion transport protein
HLK68_12150	ENOG41090T1	Membrane
HLK68_12155	ENOG41082BM	Transcriptional regulator, arsr family
HLK68_12170	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK68_12205	ENOG4105C31	Tryptophanyl-tRNA synthetase
HLK68_12220	ENOG4107SDT	Homocitrate synthase
HLK68_12230	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLK68_12235	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLK68_12270	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HLK68_12275	ENOG4105ETZ	PTS System
HLK68_12280	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK68_12295	ENOG4105WEF	catalase
HLK68_12300	ENOG4105WEF	catalase
HLK68_12330	ENOG4105BZ1	(ABC) transporter
HLK68_12340	ENOG4105BZU	Histidine kinase
HLK68_12345	ENOG4105C7Z	Conserved Protein
HLK68_12395	ENOG4105CFI	type iii restriction protein res subunit
HLK68_12410	ENOG4105ENX	hydrolase
HLK68_12435	ENOG4105CPC	Aldo Keto reductase
HLK68_12470	ENOG4105C5I	Dehydrogenase
HLK68_12480	ENOG4108MRH	transcriptional regulatory protein
HLK68_12490	ENOG4105CPC	Aldo Keto reductase
HLK68_12510	ENOG4105CN9	Peptidase m42 family protein
HLK68_12515	ENOG4105FQP	Beta-lactamase
HLK68_12540	ENOG4107QI1	Mate efflux family protein
HLK68_12565	ENOG410667J	hydrolase
HLK68_12585	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLK68_12590	ENOG4105CAQ	asparagine synthetase
HLK68_12605	ENOG4107RB3	L-asparaginase
HLK68_12615	ENOG4108JJB	ABC transporter
HLK68_12620	ENOG4105C7J	ABC transporter, permease
HLK68_12655	ENOG4105C8J	)-transporter
HLK68_12675	ENOG4105ED2	Beta-lactamase
HLK68_12685	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HLK68_12690	ENOG4105CYW	agmatinase
HLK68_12700	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HLK68_12705	ENOG4105CXN	decarboxylase
HLK68_12735	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK68_12755	ENOG4108IUM	Glycogen debranching enzyme
HLK68_12765	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HLK68_12770	ENOG4105UQX	Mate efflux family protein
HLK68_12775	ENOG4105CHR	reductase
HLK68_12785	ENOG4108RTU	Aldolase
HLK68_12790	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HLK68_12805	ENOG4105CTX	dehydratase
HLK68_12810	ENOG4107QZW	Altronate oxidoreductase
HLK68_12815	ENOG4105D2H	Uronic isomerase
HLK68_12830	ENOG4105F5H	Glycosyl Hydrolase Family 88
HLK68_12835	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HLK68_12840	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK68_12875	ENOG4108V7D	UPF0397 protein
HLK68_12880	ENOG4105CBX	hi0933 family
HLK68_12900	ENOG4108HM4	ABC transporter
HLK68_12905	ENOG4105D38	putrescine abc transporter
HLK68_12910	ENOG4105F38	ABC transporter, permease
HLK68_12915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK68_12930	ENOG4105CI3	gtp-binding protein typa
HLK68_12935	ENOG4105TQK	DNA polymerase iii, delta' subunit
HLK68_12940	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HLK68_12945	ENOG4105KQC	Competence protein
HLK68_12955	ENOG4105DXX	methyltransferase
HLK68_12965	ENOG4108WF2	Metal Dependent Phosphohydrolase
HLK68_12970	ENOG410812S	Rna-binding protein
HLK68_12980	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HLK68_12985	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HLK68_12990	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_12995	ENOG4108DWA	Nad synthetase
HLK68_13000	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HLK68_13010	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HLK68_13015	ENOG4105DBI	uridine monophosphokinase
HLK68_13020	ENOG4105CFP	Peptidase U32
HLK68_13025	ENOG4105XYU	peptidase (U32 family)
HLK68_13040	ENOG4105VPH	UPF0473 protein
HLK68_13045	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HLK68_13055	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HLK68_13065	ENOG4105C7H	Helicase, RecD TraA family
HLK68_13070	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HLK68_13080	ENOG4105UIB	(ABC) transporter
HLK68_13085	ENOG4108JQ9	ABC transporter
HLK68_13090	ENOG4107TFB	basic membrane
HLK68_13095	ENOG4105DIH	basic membrane
HLK68_13105	ENOG4105CNU	cell division protein FtsK
HLK68_13115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK68_13125	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HLK68_13130	ENOG4105E35	Dipicolinate synthase subunit A
HLK68_13140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HLK68_13145	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HLK68_13150	ENOG4105DTN	riboflavin biosynthesis protein ribF
HLK68_13155	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HLK68_13160	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLK68_13170	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HLK68_13195	ENOG4105CIN	aminoacyl-histidine dipeptidase
HLK68_13210	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HLK68_13215	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HLK68_13255	ENOG4105F9F	transposase
HLK68_13260	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HLK68_13265	ENOG4105WZW	rhodanese family
HLK68_13270	ENOG4105KTH	gatB Yqey
HLK68_13290	ENOG4105DQ6	Transposase
HLK68_13295	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HLK68_13300	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLK68_13305	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HLK68_13310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HLK68_13315	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HLK68_13320	ENOG4105CFG	Acts as a chaperone (By similarity)
HLK68_13325	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLK68_13330	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HLK68_13335	ENOG4105K63	Thioredoxin
HLK68_13345	ENOG4108HW4	amino acid AbC transporter
HLK68_13350	ENOG4107RP9	extracellular solute-binding protein, family 3
HLK68_13355	ENOG4105C98	muts2 protein
HLK68_13365	ENOG4107ZXI	Rhomboid family
HLK68_13370	ENOG4105C34	Pseudouridine synthase
HLK68_13380	ENOG4107YWA	deoxycytidylate deaminase
HLK68_13395	ENOG4105K7K	Transcriptional regulator
HLK68_13400	ENOG4105CE4	GlcNAc 6-P deacetylase
HLK68_13405	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HLK68_13415	ENOG4105DBK	s4 domain protein
HLK68_13420	ENOG41067XK	integral membrane protein
HLK68_13425	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HLK68_13430	ENOG4105DFA	alanine racemase domain protein
HLK68_13435	ENOG4105WR5	sporulation protein, YlmC YmxH family
HLK68_13445	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK68_13460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HLK68_13465	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLK68_13475	ENOG4105D4A	Cell wall formation (By similarity)
HLK68_13480	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HLK68_13485	ENOG4105CNI	cell division protein FtsW
HLK68_13490	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HLK68_13500	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HLK68_13505	ENOG4105CJN	penicillin-binding protein
HLK68_13510	ENOG4105CJN	penicillin-binding protein
HLK68_13520	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HLK68_13525	ENOG4108V6E	Cell division protein mraZ
HLK68_13530	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HLK68_13535	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLK68_13540	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HLK68_13545	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HLK68_13595	ENOG4105CEE	C4-dicarboxylate transporter
HLK68_13605	ENOG4105ENA	helicase
HLK68_13625	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HLK68_13630	ENOG4105EE0	oxidoreductase
HLK68_13650	ENOG4107RWR	Sodium hydrogen exchanger
HLK68_13670	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HLK68_13685	ENOG4105E5G	Alpha beta hydrolase fold
HLK68_13695	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HLK68_13705	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLK68_13715	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HLK68_13735	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HLK68_13740	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HLK68_13745	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HLK68_13755	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLK68_13760	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLK68_13775	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK68_13785	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HLK68_13795	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HLK68_13800	ENOG4107VMI	polysaccharide deacetylase
HLK68_13805	ENOG4105C79	DNA protecting protein DprA
HLK68_13825	ENOG4105C3F	Signal peptidase i
HLK68_13830	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HLK68_13840	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HLK68_13845	ENOG4108R3D	Electron transport complex
HLK68_13855	ENOG4105DGN	Electron transport complex
HLK68_13860	ENOG4105DZB	Electron transport complex
HLK68_13870	ENOG4105D6A	Electron transport complex
HLK68_13875	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HLK68_13905	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HLK68_13910	ENOG4106H78	methyltransferase
HLK68_13930	ENOG4105G6Z	alkaline phosphatase
HLK68_13940	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
HLK68_13945	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLK68_13950	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HLK68_13975	ENOG4105C26	Dehydrogenase
HLK68_14030	ENOG4105BZG	amino acid carrier protein
HLK68_14075	ENOG41076QQ	Glycosyl transferase, family 2
HLK68_14120	ENOG4105JVQ	RNA Polymerase
HLK68_14145	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HLK68_14160	ENOG4105EYH	Exonuclease
HLK68_14165	ENOG4107RFY	SbcCD D subunit
HLK68_14170	ENOG4105CMD	Transcriptional regulator, GntR family
HLK68_14205	ENOG4108IXY	short-chain dehydrogenase reductase
HLK68_14220	ENOG4105CB5	ATP-dependent DNA helicase recG
HLK68_14225	ENOG4105DP4	dak2 domain fusion protein ylov
HLK68_14230	ENOG4108ZAA	Alkaline-shock protein
HLK68_14235	ENOG4105VB9	50S ribosomal protein l28
HLK68_14260	ENOG4105FJ0	thiamine
HLK68_14265	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLK68_14270	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HLK68_14275	ENOG4105D9P	serine threonine protein kinase
HLK68_14280	ENOG4108ZF3	Phosphatase
HLK68_14290	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLK68_14295	ENOG4107AYK	membrAne
HLK68_14300	ENOG4107AYK	membrAne
HLK68_14305	ENOG4105QNR	S1 RNA binding domain protein
HLK68_14320	ENOG4105CNW	domain protein
HLK68_14325	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HLK68_14335	ENOG4105C25	Primosomal protein n'
HLK68_14340	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HLK68_14345	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HLK68_14355	ENOG41073R8	VanW family
HLK68_14365	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HLK68_14380	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
HLK68_14385	ENOG4108VXD	carboxy-peptidase
HLK68_14405	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HLK68_14410	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HLK68_14420	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
HLK68_14430	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HLK68_14435	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HLK68_14440	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HLK68_14445	ENOG4105CAT	Cytidine monophosphate kinase
HLK68_14460	ENOG4105FE9	pseudouridine synthase
HLK68_14470	ENOG4108JIC	nucleoside recognition domain protein
HLK68_14475	ENOG4105DZ1	carboxypeptidase
HLK68_14485	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HLK68_14505	ENOG4105CZ3	stage V sporulation protein ad
HLK68_14510	ENOG41090VF	Stage v sporulation protein ac