locus-tag	class	description
GMBLW1_00280	COG0746	molybdenum cofactor guanylyltransferase activity
GMBLW1_00290	COG0571	ribonuclease III activity
GMBLW1_00350	COG0793	Belongs to the peptidase S41A family
GMBLW1_00390	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_00430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GMBLW1_00450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GMBLW1_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GMBLW1_00470	COG0574	Belongs to the PEP-utilizing enzyme family
GMBLW1_00470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GMBLW1_00480	COG2721	sulfolactate sulfo-lyase activity
GMBLW1_00520	COG0805	protein transport
GMBLW1_00550	COG4260	virion core protein, lumpy skin disease virus
GMBLW1_00580	COG0557	exoribonuclease II activity
GMBLW1_00590	COG3481	metal-dependent phosphohydrolase, HD sub domain
GMBLW1_00610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GMBLW1_00640	COG0515	serine threonine protein kinase
GMBLW1_00640	COG2815	serine threonine protein kinase
GMBLW1_00710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_00730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_00820	COG0714	Associated with various cellular activities
GMBLW1_00880	COG1968	undecaprenyl-diphosphatase activity
GMBLW1_00940	COG0497	DNA recombination
GMBLW1_00980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GMBLW1_01000	COG1606	tRNA processing
GMBLW1_01010	COG1562	ergosterol biosynthetic process
GMBLW1_01020	COG1562	ergosterol biosynthetic process
GMBLW1_01030	COG1233	COG1233 Phytoene dehydrogenase and related
GMBLW1_01040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GMBLW1_01050	COG1597	lipid kinase activity
GMBLW1_01080	COG1309	transcriptional regulator
GMBLW1_01110	COG3119	arylsulfatase activity
GMBLW1_01140	COG2226	methyltransferase
GMBLW1_01150	COG3258	Cytochrome c
GMBLW1_01210	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_01280	COG2815	serine threonine protein kinase
GMBLW1_01280	COG0515	serine threonine protein kinase
GMBLW1_01330	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_01400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMBLW1_01420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_01460	COG0842	Transport permease protein
GMBLW1_01460	COG1129	ABC transporter
GMBLW1_01520	COG1760	l-serine dehydratase
GMBLW1_01590	COG2204	response regulator
GMBLW1_01600	COG3852	Histidine kinase
GMBLW1_01640	COG0235	Class ii aldolase
GMBLW1_01750	COG2766	serine protein kinase
GMBLW1_01760	COG2718	Belongs to the UPF0229 family
GMBLW1_01770	COG2719	SpoVR family
GMBLW1_01800	COG3848	Pyruvate phosphate dikinase
GMBLW1_01800	COG0574	Belongs to the PEP-utilizing enzyme family
GMBLW1_01820	COG4977	sequence-specific DNA binding
GMBLW1_02070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_02100	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_02210	COG2963	transposase activity
GMBLW1_02240	COG3293	Transposase
GMBLW1_02260	COG0666	response to abiotic stimulus
GMBLW1_02450	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_02490	COG2205	protein histidine kinase activity
GMBLW1_02500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GMBLW1_02510	COG0133	tryptophan synthase activity
GMBLW1_02520	COG0159	tryptophan synthase activity
GMBLW1_02540	COG3622	Belongs to the hyi family
GMBLW1_02660	COG1657	PFAM Prenyltransferase squalene oxidase
GMBLW1_02690	COG0495	leucyl-tRNA aminoacylation
GMBLW1_02740	COG0463	Glycosyl transferase, family 2
GMBLW1_02750	COG2030	dehydratase
GMBLW1_02760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMBLW1_02770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMBLW1_02790	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GMBLW1_02800	COG2815	serine threonine protein kinase
GMBLW1_02800	COG0515	serine threonine protein kinase
GMBLW1_02820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMBLW1_02830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_02850	COG1136	(ABC) transporter
GMBLW1_02850	COG0577	efflux transmembrane transporter activity
GMBLW1_02860	COG1136	(ABC) transporter
GMBLW1_02880	COG1408	metallophosphoesterase
GMBLW1_02920	COG0246	Mannitol dehydrogenase
GMBLW1_02940	COG3875	lactate racemase activity
GMBLW1_02960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GMBLW1_02960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GMBLW1_02990	COG2815	serine threonine protein kinase
GMBLW1_02990	COG0515	serine threonine protein kinase
GMBLW1_03030	COG0326	Molecular chaperone. Has ATPase activity
GMBLW1_03050	COG0052	Belongs to the universal ribosomal protein uS2 family
GMBLW1_03060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GMBLW1_03090	COG0174	glutamine synthetase
GMBLW1_03140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_03150	COG0706	membrane insertase activity
GMBLW1_03150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_03210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_03220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GMBLW1_03230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMBLW1_03250	COG0275	rRNA processing
GMBLW1_03280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMBLW1_03300	COG3119	arylsulfatase activity
GMBLW1_03420	COG0129	dihydroxy-acid dehydratase activity
GMBLW1_03460	COG0710	3-dehydroquinate dehydratase activity
GMBLW1_03470	COG0443	Heat shock 70 kDa protein
GMBLW1_03480	COG2975	iron-sulfur cluster assembly
GMBLW1_03490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GMBLW1_03500	COG0307	riboflavin synthase, alpha
GMBLW1_03510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GMBLW1_03520	COG0135	phosphoribosylanthranilate isomerase activity
GMBLW1_03530	COG4399	Belongs to the UPF0754 family
GMBLW1_03540	COG1940	carbohydrate kinase activity
GMBLW1_03560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GMBLW1_03580	COG1921	L-seryl-tRNASec selenium transferase activity
GMBLW1_03630	COG1297	OPT oligopeptide transporter protein
GMBLW1_03650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GMBLW1_03660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_03680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GMBLW1_03710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GMBLW1_03740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_03740	COG0116	Belongs to the methyltransferase superfamily
GMBLW1_03780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GMBLW1_03890	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_03920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GMBLW1_03960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_03970	COG1335	isochorismatase
GMBLW1_04010	COG3119	arylsulfatase activity
GMBLW1_04020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GMBLW1_04030	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GMBLW1_04200	COG2197	response regulator
GMBLW1_04210	COG4585	Histidine kinase
GMBLW1_04300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GMBLW1_04400	COG1305	Transglutaminase-like
GMBLW1_04410	COG2307	Protein conserved in bacteria
GMBLW1_04410	COG2308	Evidence 4 Homologs of previously reported genes of
GMBLW1_04500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMBLW1_04510	COG0622	Phosphoesterase
GMBLW1_04540	COG1733	regulation of RNA biosynthetic process
GMBLW1_04550	COG1335	isochorismatase
GMBLW1_04570	COG1741	Belongs to the pirin family
GMBLW1_04590	COG2706	6-phosphogluconolactonase activity
GMBLW1_04690	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_04750	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_04770	COG2608	mercury ion transmembrane transporter activity
GMBLW1_04770	COG2217	Heavy metal translocating P-type atpase
GMBLW1_04880	COG2183	response to ionizing radiation
GMBLW1_04890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GMBLW1_04900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GMBLW1_04910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GMBLW1_04920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GMBLW1_04930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMBLW1_04950	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMBLW1_04960	COG0356	it plays a direct role in the translocation of protons across the membrane
GMBLW1_05000	COG1477	protein flavinylation
GMBLW1_05020	COG0673	inositol 2-dehydrogenase activity
GMBLW1_05070	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_05080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GMBLW1_05100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GMBLW1_05110	COG1482	cell wall glycoprotein biosynthetic process
GMBLW1_05150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GMBLW1_05160	COG0573	inorganic phosphate transmembrane transporter activity
GMBLW1_05170	COG5002	protein histidine kinase activity
GMBLW1_05180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GMBLW1_05190	COG0704	Plays a role in the regulation of phosphate uptake
GMBLW1_05200	COG0745	RESPONSE REGULATOR receiver
GMBLW1_05240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GMBLW1_05250	COG0673	inositol 2-dehydrogenase activity
GMBLW1_05260	COG4712	double-strand break repair protein
GMBLW1_05310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_05380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_05420	COG3119	arylsulfatase activity
GMBLW1_05450	COG2204	response regulator
GMBLW1_05460	COG4191	Histidine kinase
GMBLW1_05500	COG0366	Alpha amylase catalytic
GMBLW1_05530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMBLW1_05550	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GMBLW1_05580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GMBLW1_05600	COG0066	3-isopropylmalate dehydratase activity
GMBLW1_05610	COG1090	epimerase
GMBLW1_05650	COG3693	PFAM glycoside hydrolase, family 10
GMBLW1_05650	COG3507	Belongs to the glycosyl hydrolase 43 family
GMBLW1_05650	COG2382	esterase
GMBLW1_05680	COG2135	peptidase activity
GMBLW1_05720	COG2815	serine threonine protein kinase
GMBLW1_05720	COG0515	serine threonine protein kinase
GMBLW1_05740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GMBLW1_05850	COG0189	ligase activity
GMBLW1_05880	COG0564	pseudouridine synthase activity
GMBLW1_05920	COG0585	pseudouridine synthase activity
GMBLW1_05990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GMBLW1_06010	COG0714	Associated with various cellular activities
GMBLW1_06020	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GMBLW1_06090	COG0442	prolyl-tRNA aminoacylation
GMBLW1_06110	COG1051	belongs to the nudix hydrolase family
GMBLW1_06120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GMBLW1_06130	COG0540	Belongs to the ATCase OTCase family
GMBLW1_06140	COG0646	methionine synthase
GMBLW1_06140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GMBLW1_06160	COG0405	Gamma-glutamyltransferase
GMBLW1_06190	COG0531	amino acid
GMBLW1_06200	COG4302	ethanolamine ammonia-lyase activity
GMBLW1_06210	COG4303	Ethanolamine ammonia lyase large subunit
GMBLW1_06250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GMBLW1_06290	COG0640	Transcriptional regulator
GMBLW1_06300	COG0084	hydrolase, TatD family'
GMBLW1_06320	COG1007	ATP synthesis coupled electron transport
GMBLW1_06330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMBLW1_06360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GMBLW1_06390	COG4191	Histidine kinase
GMBLW1_06410	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GMBLW1_06450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GMBLW1_06470	COG0505	Belongs to the CarA family
GMBLW1_06480	COG0640	Transcriptional regulator
GMBLW1_06510	COG0372	Belongs to the citrate synthase family
GMBLW1_06530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GMBLW1_06550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMBLW1_06560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMBLW1_06570	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMBLW1_06620	COG0714	Associated with various cellular activities
GMBLW1_06700	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GMBLW1_06750	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_06760	COG1160	GTP binding
GMBLW1_06790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GMBLW1_06800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GMBLW1_06810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GMBLW1_06850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GMBLW1_06870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GMBLW1_06880	COG0484	heat shock protein binding
GMBLW1_06890	COG0459	protein refolding
GMBLW1_06900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_06910	COG0459	protein refolding
GMBLW1_06920	COG0142	geranyltranstransferase activity
GMBLW1_06950	COG0740	serine-type endopeptidase activity
GMBLW1_06960	COG0740	serine-type endopeptidase activity
GMBLW1_06970	COG0544	peptidyl-prolyl cis-trans isomerase activity
GMBLW1_06990	COG2962	Rard protein
GMBLW1_07030	COG0705	Rhomboid family
GMBLW1_07030	COG0457	Tetratricopeptide repeat
GMBLW1_07040	COG2313	pseudouridylate synthase activity
GMBLW1_07050	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GMBLW1_07060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GMBLW1_07080	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GMBLW1_07100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GMBLW1_07100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GMBLW1_07140	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_07210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_07250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GMBLW1_07260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GMBLW1_07290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_07300	COG0552	protein localization to endoplasmic reticulum
GMBLW1_07320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GMBLW1_07340	COG1216	Glycosyl transferase, family 2
GMBLW1_07340	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_07380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GMBLW1_07390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GMBLW1_07400	COG0237	dephospho-CoA kinase activity
GMBLW1_07410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMBLW1_07410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMBLW1_07450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMBLW1_07520	COG0489	protein tyrosine kinase activity
GMBLW1_07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_07540	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_07550	COG0596	Alpha beta hydrolase
GMBLW1_07560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_07570	COG3321	synthase
GMBLW1_07570	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_07570	COG4221	oxidoreductase activity
GMBLW1_07570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GMBLW1_07580	COG0604	alcohol dehydrogenase
GMBLW1_07580	COG0604	alcohol dehydrogenase
GMBLW1_07580	COG3321	synthase
GMBLW1_07580	COG3321	synthase
GMBLW1_07590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMBLW1_07590	COG2070	2-Nitropropane dioxygenase
GMBLW1_07600	COG0720	synthase
GMBLW1_07610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GMBLW1_07640	COG0783	Belongs to the Dps family
GMBLW1_07650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GMBLW1_07660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_07680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_07710	COG0415	Belongs to the DNA photolyase family
GMBLW1_07740	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMBLW1_07750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GMBLW1_07760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GMBLW1_07770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GMBLW1_07780	COG0839	Belongs to the complex I subunit 6 family
GMBLW1_07790	COG0713	ATP synthesis coupled electron transport
GMBLW1_07800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_07840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMBLW1_07850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GMBLW1_07940	COG0811	peptide transport
GMBLW1_07950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_07980	COG1846	Transcriptional regulator
GMBLW1_08000	COG0587	DNA-directed DNA polymerase activity
GMBLW1_08010	COG0028	Belongs to the TPP enzyme family
GMBLW1_08090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GMBLW1_08100	COG0314	molybdopterin synthase activity
GMBLW1_08120	COG0277	FAD linked oxidase domain protein
GMBLW1_08120	COG0247	lactate metabolic process
GMBLW1_08130	COG0302	gtp cyclohydrolase
GMBLW1_08150	COG0330	HflC and HflK could
GMBLW1_08190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GMBLW1_08200	COG0799	negative regulation of ribosome biogenesis
GMBLW1_08210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_08220	COG4993	Dehydrogenase
GMBLW1_08260	COG1073	alpha beta
GMBLW1_08280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GMBLW1_08290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GMBLW1_08330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMBLW1_08350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_08360	COG1193	negative regulation of DNA recombination
GMBLW1_08370	COG0310	cobalt ion transport
GMBLW1_08400	COG0701	Predicted permease
GMBLW1_08410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_08470	COG0825	malonyl-CoA metabolic process
GMBLW1_08480	COG2815	serine threonine protein kinase
GMBLW1_08480	COG0515	serine threonine protein kinase
GMBLW1_08490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GMBLW1_08550	COG2272	Belongs to the type-B carboxylesterase lipase family
GMBLW1_08740	COG1061	Type III restriction enzyme res subunit
GMBLW1_09120	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_09160	COG0577	efflux transmembrane transporter activity
GMBLW1_09160	COG1136	(ABC) transporter
GMBLW1_09200	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_09210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMBLW1_09220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GMBLW1_09230	COG1716	ATPase activity
GMBLW1_09240	COG1595	DNA-templated transcription, initiation
GMBLW1_09280	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GMBLW1_09280	COG1918	ferrous iron import across plasma membrane
GMBLW1_09310	COG1091	dTDP-4-dehydrorhamnose reductase activity
GMBLW1_09350	COG0577	efflux transmembrane transporter activity
GMBLW1_09360	COG0577	efflux transmembrane transporter activity
GMBLW1_09360	COG1136	(ABC) transporter
GMBLW1_09370	COG0488	(ABC) transporter
GMBLW1_09410	COG0714	Associated with various cellular activities
GMBLW1_09520	COG0148	phosphopyruvate hydratase activity
GMBLW1_09540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GMBLW1_09630	COG5002	protein histidine kinase activity
GMBLW1_09650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_09730	COG4712	double-strand break repair protein
GMBLW1_09840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_09900	COG1104	cysteine desulfurase activity
GMBLW1_09920	COG0617	tRNA 3'-terminal CCA addition
GMBLW1_09930	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GMBLW1_09960	COG2912	Transglutaminase-like superfamily
GMBLW1_09970	COG0673	inositol 2-dehydrogenase activity
GMBLW1_09990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_10010	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GMBLW1_10030	COG0443	Heat shock 70 kDa protein
GMBLW1_10050	COG0484	heat shock protein binding
GMBLW1_10080	COG0107	imidazoleglycerol-phosphate synthase activity
GMBLW1_10140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_10150	COG1530	ribonuclease E activity
GMBLW1_10150	COG1530	ribonuclease E activity
GMBLW1_10210	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_10230	COG1560	Kdo2-lipid A biosynthetic process
GMBLW1_10240	COG0673	inositol 2-dehydrogenase activity
GMBLW1_10260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMBLW1_10260	COG0758	DNA mediated transformation
GMBLW1_10280	COG2827	Endonuclease containing a URI domain
GMBLW1_10400	COG4152	abc transporter atp-binding protein
GMBLW1_10440	COG0012	GTP binding
GMBLW1_10470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMBLW1_10530	COG1368	sulfuric ester hydrolase activity
GMBLW1_10550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GMBLW1_10560	COG2815	serine threonine protein kinase
GMBLW1_10560	COG0515	serine threonine protein kinase
GMBLW1_10590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GMBLW1_10610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GMBLW1_10620	COG5002	protein histidine kinase activity
GMBLW1_10630	COG2204	response regulator
GMBLW1_10670	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GMBLW1_10680	COG0714	Associated with various cellular activities
GMBLW1_10720	COG1408	metallophosphoesterase
GMBLW1_10780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GMBLW1_10800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GMBLW1_10970	COG3119	arylsulfatase activity
GMBLW1_11040	COG1959	2 iron, 2 sulfur cluster binding
GMBLW1_11110	COG3604	Transcriptional regulator
GMBLW1_11170	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GMBLW1_11210	COG1229	Formylmethanofuran dehydrogenase subunit A
GMBLW1_11220	COG0347	Belongs to the P(II) protein family
GMBLW1_11270	COG1132	(ABC) transporter
GMBLW1_11280	COG0189	ligase activity
GMBLW1_11280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMBLW1_11290	COG0189	ligase activity
GMBLW1_11290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMBLW1_11320	COG0515	serine threonine protein kinase
GMBLW1_11320	COG2815	serine threonine protein kinase
GMBLW1_11400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GMBLW1_11480	COG0297	glycogen (starch) synthase activity
GMBLW1_11490	COG0673	inositol 2-dehydrogenase activity
GMBLW1_11530	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMBLW1_11530	COG1024	Enoyl-CoA hydratase
GMBLW1_11550	COG0730	response to heat
GMBLW1_11580	COG1131	(ABC) transporter
GMBLW1_11610	COG2217	Heavy metal translocating P-type atpase
GMBLW1_11700	COG0437	4 iron, 4 sulfur cluster binding
GMBLW1_11740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GMBLW1_11760	COG0322	excinuclease ABC activity
GMBLW1_11770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMBLW1_11800	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMBLW1_11810	COG1129	ABC transporter
GMBLW1_11850	COG2271	Major facilitator Superfamily
GMBLW1_11860	COG1136	(ABC) transporter
GMBLW1_11890	COG0824	Thioesterase
GMBLW1_11900	COG2814	Major facilitator Superfamily
GMBLW1_11930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GMBLW1_11940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_11970	COG1846	Transcriptional regulator
GMBLW1_12000	COG0673	inositol 2-dehydrogenase activity
GMBLW1_12010	COG0277	FAD linked oxidase domain protein
GMBLW1_12020	COG0277	FAD linked oxidase domain protein
GMBLW1_12030	COG0247	lactate metabolic process
GMBLW1_12040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_12070	COG0429	hydrolase of the alpha beta-hydrolase fold
GMBLW1_12080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GMBLW1_12090	COG0515	serine threonine protein kinase
GMBLW1_12100	COG0515	serine threonine protein kinase
GMBLW1_12130	COG5492	domain, Protein
GMBLW1_12130	COG4932	domain protein
GMBLW1_12250	COG1562	ergosterol biosynthetic process
GMBLW1_12350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_12470	COG0203	ribosomal protein L17
GMBLW1_12480	COG0202	RNA polymerase activity
GMBLW1_12490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GMBLW1_12500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GMBLW1_12510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GMBLW1_12520	COG0024	Methionine aminopeptidase
GMBLW1_12530	COG0563	adenylate kinase activity
GMBLW1_12540	COG0201	protein transport
GMBLW1_12550	COG0200	Binds to the 23S rRNA
GMBLW1_12560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GMBLW1_12570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GMBLW1_12580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GMBLW1_12590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GMBLW1_12600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMBLW1_12610	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GMBLW1_12620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GMBLW1_12630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GMBLW1_12640	COG0255	Belongs to the universal ribosomal protein uL29 family
GMBLW1_12650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GMBLW1_12660	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GMBLW1_12670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GMBLW1_12680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GMBLW1_12690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GMBLW1_12700	COG0089	rRNA binding
GMBLW1_12710	COG0088	Forms part of the polypeptide exit tunnel
GMBLW1_12720	COG0051	transcription antitermination factor activity, RNA binding
GMBLW1_12730	COG0667	Aldo Keto reductase
GMBLW1_12740	COG0686	Belongs to the AlaDH PNT family
GMBLW1_12760	COG1570	exodeoxyribonuclease VII activity
GMBLW1_12770	COG1722	exodeoxyribonuclease VII activity
GMBLW1_12780	COG0142	geranyltranstransferase activity
GMBLW1_12790	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GMBLW1_12800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GMBLW1_12820	COG1132	(ABC) transporter
GMBLW1_12830	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_12850	COG4974	Belongs to the 'phage' integrase family
GMBLW1_12980	COG0420	3'-5' exonuclease activity
GMBLW1_12990	COG0419	ATPase involved in DNA repair
GMBLW1_13000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_13010	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_13070	COG1309	transcriptional regulator
GMBLW1_13080	COG1819	glycosyl
GMBLW1_13100	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_13110	COG1595	DNA-templated transcription, initiation
GMBLW1_13180	COG2165	general secretion pathway protein
GMBLW1_13200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GMBLW1_13230	COG0655	NAD(P)H dehydrogenase (quinone) activity
GMBLW1_13270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMBLW1_13290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GMBLW1_13300	COG2264	protein methyltransferase activity
GMBLW1_13310	COG3494	Protein of unknown function (DUF1009)
GMBLW1_13320	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_13360	COG0151	Belongs to the GarS family
GMBLW1_13370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GMBLW1_13390	COG0543	2 iron, 2 sulfur cluster binding
GMBLW1_13400	COG1187	pseudouridine synthase activity
GMBLW1_13450	COG2373	Large extracellular alpha-helical protein
GMBLW1_13500	COG1970	mechanosensitive ion channel activity
GMBLW1_13530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GMBLW1_13540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GMBLW1_13540	COG0519	Catalyzes the synthesis of GMP from XMP
GMBLW1_13550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMBLW1_13560	COG2814	Major facilitator Superfamily
GMBLW1_13580	COG3622	Belongs to the hyi family
GMBLW1_13630	COG0673	inositol 2-dehydrogenase activity
GMBLW1_13650	COG0134	indole-3-glycerol-phosphate synthase activity
GMBLW1_13670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GMBLW1_13680	COG0594	ribonuclease P activity
GMBLW1_13690	COG0484	heat shock protein binding
GMBLW1_13710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMBLW1_13740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_13760	COG1191	sigma factor activity
GMBLW1_13790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_13800	COG1136	(ABC) transporter
GMBLW1_13810	COG0577	efflux transmembrane transporter activity
GMBLW1_13810	COG1136	(ABC) transporter
GMBLW1_13830	COG0275	rRNA processing
GMBLW1_13850	COG1363	Peptidase, m42
GMBLW1_13860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMBLW1_13890	COG0384	phenazine biosynthesis protein PhzF
GMBLW1_13940	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_13950	COG2755	lipolytic protein G-D-S-L family
GMBLW1_13950	COG0657	acetylesterase activity
GMBLW1_13970	COG1819	glycosyl
GMBLW1_14080	COG0714	Associated with various cellular activities
GMBLW1_14160	COG0254	rRNA binding
GMBLW1_14200	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_14240	COG0640	Transcriptional regulator
GMBLW1_14320	COG0714	Associated with various cellular activities
GMBLW1_14380	COG0402	S-adenosylhomocysteine deaminase activity
GMBLW1_14410	COG1543	Belongs to the glycosyl hydrolase 57 family
GMBLW1_14440	COG1515	deoxyribonuclease V activity
GMBLW1_14480	COG0673	inositol 2-dehydrogenase activity
GMBLW1_14490	COG1074	ATP-dependent DNA helicase activity
GMBLW1_14500	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GMBLW1_14530	COG3321	synthase
GMBLW1_14530	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_14530	COG0604	alcohol dehydrogenase
GMBLW1_14560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GMBLW1_14570	COG0049	tRNA binding
GMBLW1_14590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GMBLW1_14600	COG0085	RNA polymerase activity
GMBLW1_14610	COG0222	ribosome binding
GMBLW1_14620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GMBLW1_14630	COG0081	regulation of translation
GMBLW1_14640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GMBLW1_14650	COG0250	Participates in transcription elongation, termination and antitermination
GMBLW1_14670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GMBLW1_14710	COG1774	PSP1 C-terminal conserved region
GMBLW1_14720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMBLW1_14740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMBLW1_14760	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_14800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GMBLW1_14810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_14830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_14870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GMBLW1_14900	COG5002	protein histidine kinase activity
GMBLW1_14930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GMBLW1_14950	COG5002	protein histidine kinase activity
GMBLW1_14990	COG1127	ABC transporter
GMBLW1_15000	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GMBLW1_15010	COG2239	Acts as a magnesium transporter
GMBLW1_15020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GMBLW1_15120	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_15120	COG1506	peptidase
GMBLW1_15120	COG4946	Tricorn protease homolog
GMBLW1_15160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GMBLW1_15170	COG0745	RESPONSE REGULATOR receiver
GMBLW1_15180	COG5002	protein histidine kinase activity
GMBLW1_15200	COG0165	Argininosuccinate lyase
GMBLW1_15210	COG0019	diaminopimelate decarboxylase activity
GMBLW1_15240	COG3684	Belongs to the aldolase LacD family
GMBLW1_15260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GMBLW1_15280	COG1131	(ABC) transporter
GMBLW1_15310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GMBLW1_15340	COG1061	Type III restriction enzyme res subunit
GMBLW1_15510	COG2271	Major facilitator Superfamily
GMBLW1_15570	COG0824	Thioesterase
GMBLW1_15580	COG0681	Belongs to the peptidase S26 family
GMBLW1_15590	COG0681	Belongs to the peptidase S26 family
GMBLW1_15600	COG0481	GTPase activity
GMBLW1_15620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_15690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GMBLW1_15720	COG0517	IMP dehydrogenase activity
GMBLW1_15720	COG0516	GMP reductase activity
GMBLW1_15770	COG0736	holo-[acyl-carrier-protein] synthase activity
GMBLW1_15790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMBLW1_15810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMBLW1_15850	COG0612	Peptidase, M16
GMBLW1_15950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_15960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMBLW1_15960	COG1321	iron dependent repressor
GMBLW1_15970	COG1121	(ABC) transporter
GMBLW1_15980	COG0803	Belongs to the bacterial solute-binding protein 9 family
GMBLW1_15990	COG1132	(ABC) transporter
GMBLW1_16000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_16030	COG0095	Lipoate-protein ligase
GMBLW1_16040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GMBLW1_16060	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMBLW1_16080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMBLW1_16090	COG0509	glycine decarboxylation via glycine cleavage system
GMBLW1_16100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMBLW1_16110	COG3119	arylsulfatase activity
GMBLW1_16120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMBLW1_16210	COG2890	protein-(glutamine-N5) methyltransferase activity
GMBLW1_16220	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMBLW1_16240	COG4221	oxidoreductase activity
GMBLW1_16350	COG1013	pyruvate-flavodoxin oxidoreductase activity
GMBLW1_16360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GMBLW1_16360	COG0674	pyruvate-flavodoxin oxidoreductase activity
GMBLW1_16410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMBLW1_16410	COG0426	domain, Protein
GMBLW1_16420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GMBLW1_16480	COG0423	glycine-tRNA ligase activity
GMBLW1_16490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GMBLW1_16520	COG0564	pseudouridine synthase activity
GMBLW1_16530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GMBLW1_16540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GMBLW1_16560	COG0187	DNA topoisomerase II activity
GMBLW1_16570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GMBLW1_16600	COG0352	thiamine-phosphate diphosphorylase activity
GMBLW1_16610	COG0514	ATP-dependent DNA helicase (RecQ)
GMBLW1_16670	COG2815	serine threonine protein kinase
GMBLW1_16670	COG0515	serine threonine protein kinase
GMBLW1_16790	COG1053	succinate dehydrogenase
GMBLW1_16800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GMBLW1_16810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GMBLW1_16830	COG0071	Belongs to the small heat shock protein (HSP20) family
GMBLW1_16860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_16870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_16890	COG0297	glycogen (starch) synthase activity
GMBLW1_16920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GMBLW1_16950	COG0793	Belongs to the peptidase S41A family
GMBLW1_16960	COG1162	GTPase activity
GMBLW1_16980	COG0443	Heat shock 70 kDa protein
GMBLW1_16990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GMBLW1_17010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_17040	COG0784	Response regulator, receiver
GMBLW1_17040	COG2198	Histidine kinase
GMBLW1_17040	COG0643	Histidine kinase
GMBLW1_17070	COG2201	protein-glutamate methylesterase activity
GMBLW1_17080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GMBLW1_17090	COG2815	serine threonine protein kinase
GMBLW1_17090	COG0515	serine threonine protein kinase
GMBLW1_17120	COG0113	porphobilinogen synthase activity
GMBLW1_17140	COG1937	Protein conserved in bacteria
GMBLW1_17150	COG2217	Heavy metal translocating P-type atpase
GMBLW1_17270	COG2814	Major facilitator Superfamily
GMBLW1_17340	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_17380	COG0515	serine threonine protein kinase
GMBLW1_17380	COG2815	serine threonine protein kinase
GMBLW1_17410	COG3505	Type IV secretory pathway VirD4
GMBLW1_17490	COG1668	transmembrane transport
GMBLW1_17520	COG2755	lipolytic protein G-D-S-L family
GMBLW1_17520	COG0657	acetylesterase activity
GMBLW1_17540	COG0698	ribose 5-phosphate isomerase
GMBLW1_17550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMBLW1_17570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GMBLW1_17570	COG0037	tRNA processing
GMBLW1_17580	COG1546	Belongs to the CinA family
GMBLW1_17580	COG1058	Belongs to the CinA family
GMBLW1_17590	COG2271	Major facilitator Superfamily
GMBLW1_17600	COG1331	Highly conserved protein containing a thioredoxin domain
GMBLW1_18060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_18220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_18280	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GMBLW1_18290	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_18330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GMBLW1_18330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GMBLW1_18340	COG1663	tetraacyldisaccharide 4'-kinase activity
GMBLW1_18400	COG0022	dehydrogenase e1 component
GMBLW1_18440	COG0459	protein refolding
GMBLW1_18450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_18470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GMBLW1_18530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GMBLW1_18550	COG0343	queuine tRNA-ribosyltransferase activity
GMBLW1_18560	COG0202	RNA polymerase activity
GMBLW1_18600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GMBLW1_18610	COG0564	pseudouridine synthase activity
GMBLW1_18700	COG2963	transposase activity
GMBLW1_18750	COG1401	restriction endodeoxyribonuclease activity
GMBLW1_18760	COG4935	Belongs to the peptidase S8 family
GMBLW1_18760	COG1404	Belongs to the peptidase S8 family
GMBLW1_18780	COG0717	Belongs to the dCTP deaminase family
GMBLW1_18850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GMBLW1_18850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GMBLW1_18900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMBLW1_18960	COG2271	Major facilitator Superfamily
GMBLW1_19000	COG1942	4-Oxalocrotonate Tautomerase
GMBLW1_19060	COG0649	NAD binding
GMBLW1_19070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_19080	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_19100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_19230	COG0018	arginyl-trna synthetase
GMBLW1_19300	COG1611	Belongs to the LOG family
GMBLW1_19320	COG1252	NADH dehydrogenase
GMBLW1_19340	COG0521	Mo-molybdopterin cofactor biosynthetic process
GMBLW1_19380	COG0646	methionine synthase
GMBLW1_19380	COG1410	methionine synthase
GMBLW1_19400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GMBLW1_19410	COG0515	serine threonine protein kinase
GMBLW1_19410	COG2815	serine threonine protein kinase
GMBLW1_19480	COG2815	serine threonine protein kinase
GMBLW1_19480	COG0515	serine threonine protein kinase
GMBLW1_19510	COG1506	peptidase
GMBLW1_19510	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_19510	COG4946	Tricorn protease homolog
GMBLW1_19520	COG0667	Aldo Keto reductase
GMBLW1_19530	COG0539	negative regulation of cytoplasmic translation
GMBLW1_19550	COG0463	Glycosyl transferase, family 2
GMBLW1_19600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_19600	COG0515	serine threonine protein kinase
GMBLW1_19610	COG1872	DUF167
GMBLW1_19620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GMBLW1_19640	COG0726	polysaccharide deacetylase
GMBLW1_19660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMBLW1_19670	COG0430	RNA-3'-phosphate cyclase activity
GMBLW1_19770	COG0328	RNA-DNA hybrid ribonuclease activity
GMBLW1_19780	COG1214	PFAM Peptidase M22, glycoprotease
GMBLW1_19830	COG3069	C4-dicarboxylate transmembrane transporter activity
GMBLW1_19890	COG0126	phosphoglycerate kinase activity
GMBLW1_20030	COG4191	Histidine kinase
GMBLW1_20040	COG1185	polyribonucleotide nucleotidyltransferase activity
GMBLW1_20050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GMBLW1_20060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_20130	COG0515	serine threonine protein kinase
GMBLW1_20130	COG2815	serine threonine protein kinase
GMBLW1_20240	COG3059	membrane
GMBLW1_20290	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_20330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_20350	COG0436	Aminotransferase
GMBLW1_20380	COG0798	PFAM Bile acid sodium symporter
GMBLW1_20390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GMBLW1_20440	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
GMBLW1_20510	COG0515	serine threonine protein kinase
GMBLW1_20590	COG0352	thiamine-phosphate diphosphorylase activity
GMBLW1_20590	COG0351	phosphomethylpyrimidine kinase
GMBLW1_20600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GMBLW1_20630	COG0456	acetyltransferase
GMBLW1_20670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_20730	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_20840	COG0584	glycerophosphoryl diester phosphodiesterase
GMBLW1_20870	COG1595	DNA-templated transcription, initiation
GMBLW1_20910	COG0515	serine threonine protein kinase
GMBLW1_20910	COG2815	serine threonine protein kinase
GMBLW1_20920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMBLW1_20970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GMBLW1_21020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMBLW1_21090	COG0714	Associated with various cellular activities
GMBLW1_21130	COG2084	Dehydrogenase
GMBLW1_21160	COG0745	RESPONSE REGULATOR receiver
GMBLW1_21170	COG5002	protein histidine kinase activity
GMBLW1_21450	COG0436	Aminotransferase
GMBLW1_21460	COG0488	(ABC) transporter
GMBLW1_21540	COG0537	adenosine 5'-monophosphoramidase activity
GMBLW1_21620	COG0515	serine threonine protein kinase
GMBLW1_21620	COG2815	serine threonine protein kinase
GMBLW1_21640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GMBLW1_21690	COG0515	serine threonine protein kinase
GMBLW1_21690	COG2815	serine threonine protein kinase
GMBLW1_21720	COG0504	CTP synthase activity
GMBLW1_21730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GMBLW1_22060	COG3781	membrane
GMBLW1_22070	COG1361	Conserved repeat domain
GMBLW1_22080	COG0483	inositol monophosphate 1-phosphatase activity
GMBLW1_22100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GMBLW1_22110	COG2204	response regulator
GMBLW1_22230	COG0181	hydroxymethylbilane synthase activity
GMBLW1_22250	COG0515	serine threonine protein kinase
GMBLW1_22260	COG0515	serine threonine protein kinase
GMBLW1_22290	COG0750	zinc metalloprotease
GMBLW1_22300	COG0750	zinc metalloprotease
GMBLW1_22390	COG1793	dna ligase
GMBLW1_22440	COG4537	Required for transformation and DNA binding
GMBLW1_22490	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_22510	COG0564	pseudouridine synthase activity
GMBLW1_22530	COG4336	lyase activity
GMBLW1_22550	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GMBLW1_22560	COG1468	defense response to virus
GMBLW1_22560	COG1518	maintenance of DNA repeat elements
GMBLW1_22650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMBLW1_22650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMBLW1_22660	COG0586	Pfam SNARE associated Golgi protein
GMBLW1_22680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_22710	COG0204	Acyl-transferase
GMBLW1_22710	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_22800	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GMBLW1_22820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GMBLW1_22830	COG0287	Prephenate dehydrogenase
GMBLW1_22840	COG2124	cytochrome p450
GMBLW1_22870	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_22880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_22920	COG4555	ABC transporter
GMBLW1_22990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GMBLW1_23010	COG5002	protein histidine kinase activity
GMBLW1_23310	COG0420	3'-5' exonuclease activity
GMBLW1_23320	COG0419	ATPase involved in DNA repair
GMBLW1_23420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GMBLW1_23430	COG1846	Transcriptional regulator
GMBLW1_23440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GMBLW1_23600	COG2832	Protein of unknown function (DUF454)
GMBLW1_23610	COG0166	Belongs to the GPI family
GMBLW1_23620	COG0646	methionine synthase
GMBLW1_23620	COG1410	methionine synthase
GMBLW1_23630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GMBLW1_23660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GMBLW1_23690	COG2815	serine threonine protein kinase
GMBLW1_23690	COG0515	serine threonine protein kinase
GMBLW1_23700	COG0004	ammonium transporteR
GMBLW1_23760	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMBLW1_23770	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMBLW1_23790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GMBLW1_23810	COG3119	arylsulfatase activity
GMBLW1_23830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GMBLW1_23850	COG0577	efflux transmembrane transporter activity
GMBLW1_23850	COG1136	(ABC) transporter
GMBLW1_23880	COG0347	Belongs to the P(II) protein family
GMBLW1_23920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GMBLW1_23930	COG1966	Carbon starvation protein
GMBLW1_23940	COG0515	serine threonine protein kinase
GMBLW1_23940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_24070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMBLW1_24100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMBLW1_24140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GMBLW1_24210	COG2350	Protein conserved in bacteria
GMBLW1_24240	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_24270	COG2081	HI0933 family
GMBLW1_24280	COG2226	methyltransferase
GMBLW1_24390	COG0542	response to heat
GMBLW1_24410	COG0515	serine threonine protein kinase
GMBLW1_24410	COG2815	serine threonine protein kinase
GMBLW1_24420	COG0515	serine threonine protein kinase
GMBLW1_24420	COG2815	serine threonine protein kinase
GMBLW1_24430	COG0243	molybdopterin cofactor binding
GMBLW1_24460	COG0720	synthase
GMBLW1_24470	COG0616	signal peptide processing
GMBLW1_24510	COG2268	Band 7 protein
GMBLW1_24560	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_24560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GMBLW1_24610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GMBLW1_24650	COG0671	phosphoesterase, PA-phosphatase related
GMBLW1_24650	COG2453	phosphatase
GMBLW1_24680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMBLW1_24700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GMBLW1_24870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_24910	COG4864	UPF0365 protein
GMBLW1_24940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_24970	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GMBLW1_25020	COG4974	Belongs to the 'phage' integrase family
GMBLW1_25030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GMBLW1_25110	COG3119	arylsulfatase activity
GMBLW1_25120	COG0515	serine threonine protein kinase
GMBLW1_25120	COG2815	serine threonine protein kinase
GMBLW1_25130	COG1473	amidohydrolase
GMBLW1_25140	COG4948	Mandelate Racemase Muconate Lactonizing
GMBLW1_25180	COG2815	serine threonine protein kinase
GMBLW1_25180	COG0515	serine threonine protein kinase
GMBLW1_25190	COG2815	serine threonine protein kinase
GMBLW1_25190	COG0515	serine threonine protein kinase
GMBLW1_25210	COG0633	Ferredoxin
GMBLW1_25320	COG2815	serine threonine protein kinase
GMBLW1_25320	COG0515	serine threonine protein kinase
GMBLW1_25340	COG0714	Associated with various cellular activities
GMBLW1_25360	COG1696	Membrane protein involved in D-alanine export
GMBLW1_25420	COG0124	histidyl-tRNA synthetase
GMBLW1_25440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMBLW1_25450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GMBLW1_25570	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_25610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_25610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_25630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMBLW1_25640	COG1643	Atp-dependent helicase
GMBLW1_25650	COG0515	serine threonine protein kinase
GMBLW1_25660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GMBLW1_25760	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GMBLW1_25790	COG0105	UTP biosynthetic process
GMBLW1_25890	COG2815	serine threonine protein kinase
GMBLW1_25890	COG0515	serine threonine protein kinase
GMBLW1_25920	COG1253	flavin adenine dinucleotide binding
GMBLW1_25930	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_25930	COG1506	peptidase
GMBLW1_25940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GMBLW1_26000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_26010	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_26110	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_26130	COG0457	Tetratricopeptide repeat
GMBLW1_26130	COG3118	belongs to the thioredoxin family
GMBLW1_26140	COG0693	protein deglycase activity
GMBLW1_26280	COG2046	Belongs to the sulfate adenylyltransferase family
GMBLW1_26300	COG0175	sulfate reduction
GMBLW1_26410	COG0023	Translation Initiation Factor
GMBLW1_26760	COG2815	serine threonine protein kinase
GMBLW1_26760	COG0515	serine threonine protein kinase
GMBLW1_26780	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMBLW1_26840	COG0095	Lipoate-protein ligase
GMBLW1_26860	COG2860	membrane
GMBLW1_26920	COG0424	maF-like protein
GMBLW1_26940	COG2318	DinB family
GMBLW1_26950	COG0515	serine threonine protein kinase
GMBLW1_26950	COG2815	serine threonine protein kinase
GMBLW1_27010	COG0515	serine threonine protein kinase
GMBLW1_27020	COG0515	serine threonine protein kinase
GMBLW1_27020	COG2815	serine threonine protein kinase
GMBLW1_27040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GMBLW1_27080	COG0542	response to heat
GMBLW1_27160	COG0529	Catalyzes the synthesis of activated sulfate
GMBLW1_27180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GMBLW1_27260	COG0156	8-amino-7-oxononanoate synthase activity
GMBLW1_27270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GMBLW1_27290	COG2211	Major facilitator Superfamily
GMBLW1_27300	COG2815	serine threonine protein kinase
GMBLW1_27300	COG0515	serine threonine protein kinase
GMBLW1_27320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GMBLW1_27340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GMBLW1_27350	COG0195	Participates in both transcription termination and antitermination
GMBLW1_27350	COG2251	uridine kinase activity
GMBLW1_27360	COG3842	ATPase activity
GMBLW1_27520	COG2204	response regulator
GMBLW1_27550	COG0501	Belongs to the peptidase M48B family
GMBLW1_27720	COG1506	peptidase
GMBLW1_27720	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_27810	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_27910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_27920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_27930	COG3002	Belongs to the UPF0753 family
GMBLW1_27980	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_27990	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_28150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_28250	COG0667	Aldo Keto reductase
GMBLW1_28260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_28320	COG2095	MarC family integral membrane protein
GMBLW1_28340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GMBLW1_28340	COG2199	diguanylate cyclase activity
GMBLW1_28440	COG1216	Glycosyl transferase, family 2
GMBLW1_28440	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_28450	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
GMBLW1_28490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_28520	COG0515	serine threonine protein kinase
GMBLW1_28520	COG2815	serine threonine protein kinase
GMBLW1_28530	COG0515	serine threonine protein kinase
GMBLW1_28530	COG2815	serine threonine protein kinase
GMBLW1_28630	COG0303	'Molybdopterin
GMBLW1_28640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GMBLW1_28650	COG1073	alpha beta
GMBLW1_28660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GMBLW1_28660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GMBLW1_28670	COG0492	ferredoxin-NADP+ reductase activity
GMBLW1_28730	COG1199	ATP-dependent helicase activity
GMBLW1_28750	COG4974	Belongs to the 'phage' integrase family
GMBLW1_28880	COG3621	Patatin-like phospholipase
GMBLW1_29020	COG1166	arginine decarboxylase activity
GMBLW1_29070	COG0515	serine threonine protein kinase
GMBLW1_29070	COG2815	serine threonine protein kinase
GMBLW1_29090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMBLW1_29100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GMBLW1_29130	COG0515	serine threonine protein kinase
GMBLW1_29130	COG2815	serine threonine protein kinase
GMBLW1_29150	COG1045	serine acetyltransferase
GMBLW1_29200	COG0673	inositol 2-dehydrogenase activity
GMBLW1_29210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GMBLW1_29220	COG1984	allophanate hydrolase subunit 2
GMBLW1_29280	COG0714	Associated with various cellular activities
GMBLW1_29300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMBLW1_29310	COG1573	uracil-dna glycosylase
GMBLW1_29350	COG1674	ftsk spoiiie
GMBLW1_29350	COG4980	gas vesicle protein
GMBLW1_29360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GMBLW1_29380	COG1979	alcohol dehydrogenase
GMBLW1_29390	COG1620	l-lactate permease
GMBLW1_29400	COG0515	serine threonine protein kinase
GMBLW1_29400	COG2815	serine threonine protein kinase
GMBLW1_29430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GMBLW1_29460	COG1131	(ABC) transporter
GMBLW1_29500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GMBLW1_29510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GMBLW1_29530	COG0189	ligase activity
GMBLW1_29530	COG4067	protein conserved in archaea
GMBLW1_29620	COG1131	(ABC) transporter
GMBLW1_29700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMBLW1_29720	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GMBLW1_29770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_29780	COG0243	molybdopterin cofactor binding
GMBLW1_29790	COG2146	nitrite reductase [NAD(P)H] activity
GMBLW1_29800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMBLW1_29810	COG1648	precorrin-2 dehydrogenase activity
GMBLW1_29810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GMBLW1_29820	COG4191	Histidine kinase
GMBLW1_29840	COG2319	Wd-40 repeat
GMBLW1_29840	COG4249	Peptidase C14 caspase catalytic subunit p20
GMBLW1_29900	COG0523	cobalamin synthesis protein
GMBLW1_29940	COG2814	Major facilitator Superfamily
GMBLW1_30010	COG3963	phosphatidate phosphatase activity
GMBLW1_30100	COG3401	FG-GAP repeat protein
GMBLW1_30150	COG1902	pentaerythritol trinitrate reductase activity
GMBLW1_30180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMBLW1_30220	COG3540	Alkaline phosphatase
GMBLW1_30240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMBLW1_30250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMBLW1_30370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GMBLW1_30380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GMBLW1_30390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GMBLW1_30510	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_30560	COG1007	ATP synthesis coupled electron transport
GMBLW1_30580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMBLW1_30590	COG0713	ATP synthesis coupled electron transport
GMBLW1_30600	COG0839	Belongs to the complex I subunit 6 family
GMBLW1_30610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_30620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GMBLW1_30630	COG1034	ATP synthesis coupled electron transport
GMBLW1_30670	COG0649	NAD binding
GMBLW1_30680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_30690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_30700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GMBLW1_30720	COG0166	Belongs to the GPI family
GMBLW1_30730	COG0656	L-ascorbic acid biosynthetic process
GMBLW1_30740	COG1063	alcohol dehydrogenase
GMBLW1_30760	COG0673	inositol 2-dehydrogenase activity
GMBLW1_30780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMBLW1_30810	COG0515	serine threonine protein kinase
GMBLW1_30810	COG2815	serine threonine protein kinase
GMBLW1_31080	COG1022	Amp-dependent synthetase and ligase
GMBLW1_31090	COG2211	Major facilitator Superfamily
GMBLW1_31100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GMBLW1_31110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GMBLW1_31120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GMBLW1_31640	COG3210	domain, Protein
GMBLW1_32110	COG0443	Heat shock 70 kDa protein
GMBLW1_32130	COG1691	(AIR) carboxylase
GMBLW1_32140	COG3321	synthase
GMBLW1_32140	COG0604	alcohol dehydrogenase
GMBLW1_32140	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_32150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMBLW1_32160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GMBLW1_32220	COG3201	nicotinamide mononucleotide transporter
GMBLW1_32230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GMBLW1_32230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GMBLW1_32260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GMBLW1_32310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMBLW1_32330	COG3437	response regulator, receiver
GMBLW1_32350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_32360	COG0539	negative regulation of cytoplasmic translation
GMBLW1_32380	COG2815	serine threonine protein kinase
GMBLW1_32380	COG0515	serine threonine protein kinase
GMBLW1_32430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GMBLW1_32480	COG0515	serine threonine protein kinase
GMBLW1_32480	COG2815	serine threonine protein kinase
GMBLW1_32550	COG0028	Belongs to the TPP enzyme family
GMBLW1_32570	COG1218	3'(2'),5'-bisphosphate nucleotidase
GMBLW1_32620	COG0673	inositol 2-dehydrogenase activity
GMBLW1_32640	COG0131	Imidazoleglycerol-phosphate dehydratase
GMBLW1_32820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GMBLW1_32840	COG0515	serine threonine protein kinase
GMBLW1_32840	COG2815	serine threonine protein kinase
GMBLW1_32890	COG1215	transferase activity, transferring glycosyl groups
GMBLW1_32910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_32920	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_32970	COG1674	ftsk spoiiie
GMBLW1_33120	COG3118	belongs to the thioredoxin family
GMBLW1_33140	COG0167	dihydroorotate dehydrogenase activity
GMBLW1_33150	COG0515	serine threonine protein kinase
GMBLW1_33150	COG2815	serine threonine protein kinase
GMBLW1_33160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_33160	COG0072	phenylalanine-tRNA ligase activity
GMBLW1_33200	COG1506	peptidase
GMBLW1_33200	COG4946	Tricorn protease homolog
GMBLW1_33200	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_33320	COG1459	type II secretion system
GMBLW1_33380	COG1132	(ABC) transporter
GMBLW1_33450	COG2264	protein methyltransferase activity
GMBLW1_33480	COG1304	FMN binding
GMBLW1_33510	COG1475	DNA binding
GMBLW1_33540	COG1796	DNA polymerase
GMBLW1_33540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMBLW1_33550	COG0542	response to heat
GMBLW1_33560	COG0542	response to heat
GMBLW1_33600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_33610	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_33620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMBLW1_33630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMBLW1_33640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_33650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_33690	COG0745	RESPONSE REGULATOR receiver
GMBLW1_33700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMBLW1_33720	COG0724	RNA recognition motif
GMBLW1_33740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GMBLW1_33770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMBLW1_33790	COG0784	Response regulator, receiver
GMBLW1_33790	COG4191	Histidine kinase
GMBLW1_33830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_33840	COG3938	Belongs to the proline racemase family
GMBLW1_33850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMBLW1_33930	COG0592	DNA-directed DNA polymerase activity
GMBLW1_33940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMBLW1_33950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GMBLW1_34010	COG0123	including yeast histone deacetylase and acetoin utilization protein
GMBLW1_34120	COG0673	inositol 2-dehydrogenase activity
GMBLW1_34130	COG0673	inositol 2-dehydrogenase activity
GMBLW1_34170	COG1136	(ABC) transporter
GMBLW1_34180	COG2226	methyltransferase
GMBLW1_34190	COG3795	YCII-related domain
GMBLW1_34230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GMBLW1_34240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GMBLW1_34270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GMBLW1_34370	COG0714	Associated with various cellular activities
GMBLW1_34430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_34460	COG0406	alpha-ribazole phosphatase activity
GMBLW1_34490	COG0546	phosphoglycolate phosphatase activity
GMBLW1_34500	COG2198	Histidine kinase
GMBLW1_34500	COG0784	Response regulator, receiver
GMBLW1_34500	COG5002	protein histidine kinase activity
GMBLW1_34530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GMBLW1_34540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GMBLW1_34550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GMBLW1_34560	COG0233	cytoplasmic translational termination
GMBLW1_34570	COG0528	UMP kinase activity
GMBLW1_34660	COG0754	glutathionylspermidine amidase activity
GMBLW1_34710	COG2258	MOSC domain
GMBLW1_34740	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMBLW1_34770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GMBLW1_34770	COG0321	lipoyl(octanoyl) transferase activity
GMBLW1_34780	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GMBLW1_34800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GMBLW1_34940	COG4964	Belongs to the GSP D family
GMBLW1_35000	COG4106	trans-aconitate 2-methyltransferase activity
GMBLW1_35020	COG0473	3-isopropylmalate dehydrogenase activity
GMBLW1_35080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMBLW1_35080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GMBLW1_35150	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_35190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GMBLW1_35200	COG0673	inositol 2-dehydrogenase activity
GMBLW1_35230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMBLW1_35290	COG0842	Transport permease protein
GMBLW1_35290	COG1129	ABC transporter
GMBLW1_35360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GMBLW1_35370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GMBLW1_35430	COG0861	Integral membrane protein TerC family
GMBLW1_35460	COG0673	inositol 2-dehydrogenase activity
GMBLW1_35480	COG0583	DNA-binding transcription factor activity
GMBLW1_35490	COG0318	PFAM AMP-dependent synthetase and ligase
GMBLW1_35550	COG3132	Protein of unknown function, DUF480
GMBLW1_35560	COG1858	cytochrome C peroxidase
GMBLW1_35600	COG5564	TIM-barrel signal transduction protein
GMBLW1_35620	COG2815	serine threonine protein kinase
GMBLW1_35620	COG0515	serine threonine protein kinase
GMBLW1_35630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GMBLW1_35670	COG1136	(ABC) transporter
GMBLW1_35680	COG4591	ABC-type transport system involved in lipoprotein release permease component
GMBLW1_35690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GMBLW1_35730	COG0482	sulfurtransferase activity
GMBLW1_35760	COG0515	serine threonine protein kinase
GMBLW1_35760	COG2815	serine threonine protein kinase
GMBLW1_35800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMBLW1_36070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_36170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_36230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMBLW1_36320	COG3119	arylsulfatase activity
GMBLW1_36340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMBLW1_36400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMBLW1_36410	COG2815	serine threonine protein kinase
GMBLW1_36410	COG0515	serine threonine protein kinase
GMBLW1_36440	COG0440	acetolactate synthase activity
GMBLW1_36480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GMBLW1_36500	COG2271	Major facilitator Superfamily
GMBLW1_36570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GMBLW1_36590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GMBLW1_36650	COG0515	serine threonine protein kinase
GMBLW1_36650	COG2815	serine threonine protein kinase
GMBLW1_36680	COG2226	methyltransferase
GMBLW1_36690	COG2815	serine threonine protein kinase
GMBLW1_36690	COG0515	serine threonine protein kinase
GMBLW1_36720	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMBLW1_36750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GMBLW1_36760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GMBLW1_36790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GMBLW1_36820	COG0515	serine threonine protein kinase
GMBLW1_36820	COG2815	serine threonine protein kinase
GMBLW1_36830	COG1132	(ABC) transporter
GMBLW1_36850	COG0556	nucleotide-excision repair
GMBLW1_36880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_36890	COG3119	arylsulfatase activity
GMBLW1_36920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GMBLW1_36960	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GMBLW1_36980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GMBLW1_36990	COG0515	serine threonine protein kinase
GMBLW1_36990	COG2815	serine threonine protein kinase
GMBLW1_37060	COG1595	DNA-templated transcription, initiation
GMBLW1_37130	COG1505	serine-type exopeptidase activity
GMBLW1_37170	COG0515	serine threonine protein kinase
GMBLW1_37170	COG2815	serine threonine protein kinase
GMBLW1_37200	COG0516	GMP reductase activity
GMBLW1_37200	COG0517	IMP dehydrogenase activity
GMBLW1_37220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GMBLW1_37240	COG1073	alpha beta
GMBLW1_37270	COG3119	arylsulfatase activity
GMBLW1_37350	COG2264	protein methyltransferase activity
GMBLW1_37360	COG0515	serine threonine protein kinase
GMBLW1_37360	COG2815	serine threonine protein kinase
GMBLW1_37370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GMBLW1_37390	COG0346	lactoylglutathione lyase activity
GMBLW1_37440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GMBLW1_37490	COG1136	(ABC) transporter
GMBLW1_37510	COG0367	asparagine synthase
GMBLW1_37520	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_37610	COG4145	pantothenate transmembrane transporter activity
GMBLW1_37620	COG1064	alcohol dehydrogenase
GMBLW1_37650	COG2226	methyltransferase
GMBLW1_37690	COG0415	Belongs to the DNA photolyase family
GMBLW1_37760	COG1073	alpha beta
GMBLW1_38290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GMBLW1_38320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GMBLW1_38330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GMBLW1_38340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GMBLW1_38390	COG0408	coproporphyrinogen oxidase activity
GMBLW1_38560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMBLW1_38570	COG0514	ATP-dependent DNA helicase (RecQ)
GMBLW1_38610	COG1201	RNA secondary structure unwinding
GMBLW1_38710	COG0602	queuosine metabolic process
GMBLW1_38730	COG2963	transposase activity
GMBLW1_38770	COG1192	Involved in chromosome partitioning
GMBLW1_38880	COG1215	transferase activity, transferring glycosyl groups
GMBLW1_38890	COG0629	single-stranded DNA binding
GMBLW1_39000	COG0673	inositol 2-dehydrogenase activity
GMBLW1_39110	COG0358	DNA primase activity
GMBLW1_39120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMBLW1_39190	COG0443	Heat shock 70 kDa protein
GMBLW1_39200	COG0698	ribose 5-phosphate isomerase
GMBLW1_39320	COG0347	Belongs to the P(II) protein family
GMBLW1_39400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMBLW1_39460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMBLW1_39510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GMBLW1_39630	COG0842	Transport permease protein
GMBLW1_39630	COG1131	(ABC) transporter
GMBLW1_39630	COG1716	ATPase activity
GMBLW1_39640	COG3361	conserved protein (COG2071)
GMBLW1_39690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_40230	COG2815	serine threonine protein kinase
GMBLW1_40230	COG0515	serine threonine protein kinase
GMBLW1_40290	COG1196	nuclear chromosome segregation
GMBLW1_40320	COG1196	nuclear chromosome segregation
GMBLW1_40360	COG1196	nuclear chromosome segregation
GMBLW1_40370	COG1706	bacterial-type flagellum-dependent cell motility
GMBLW1_40380	COG3104	oligopeptide transport
GMBLW1_40450	COG1408	metallophosphoesterase
GMBLW1_40600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GMBLW1_40690	COG2304	oxidoreductase activity
GMBLW1_40980	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GMBLW1_41020	COG1131	(ABC) transporter
GMBLW1_41030	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GMBLW1_41040	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GMBLW1_41050	COG1126	abc transporter atp-binding protein
GMBLW1_41060	COG0765	amino acid transport
GMBLW1_41080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GMBLW1_41090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GMBLW1_41100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GMBLW1_41190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_41200	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_41220	COG0138	bifunctional purine biosynthesis protein purh
GMBLW1_41230	COG4245	von Willebrand factor, type A
GMBLW1_41250	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
GMBLW1_41300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMBLW1_41330	COG0753	catalase activity
GMBLW1_41350	COG0714	Associated with various cellular activities
GMBLW1_41370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMBLW1_41390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GMBLW1_41400	COG0242	peptide deformylase activity
GMBLW1_41450	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GMBLW1_41460	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GMBLW1_41530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GMBLW1_41540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GMBLW1_41550	COG0205	6-phosphofructokinase activity
GMBLW1_41590	COG1648	precorrin-2 dehydrogenase activity
GMBLW1_41590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GMBLW1_41630	COG3293	Transposase
GMBLW1_41710	COG2855	membrane
GMBLW1_41730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GMBLW1_41840	COG4651	solute:proton antiporter activity
GMBLW1_41840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GMBLW1_41850	COG1119	ATPase activity
GMBLW1_41890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GMBLW1_41920	COG1201	RNA secondary structure unwinding
GMBLW1_41930	COG1793	dna ligase
GMBLW1_41950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMBLW1_41960	COG0275	rRNA processing
GMBLW1_42060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GMBLW1_42070	COG0228	four-way junction DNA binding
GMBLW1_42080	COG0336	Belongs to the RNA methyltransferase TrmD family
GMBLW1_42090	COG0335	large ribosomal subunit rRNA binding
GMBLW1_42100	COG0792	nuclease activity
GMBLW1_42110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GMBLW1_42130	COG5002	protein histidine kinase activity
GMBLW1_42160	COG1104	cysteine desulfurase activity
GMBLW1_42170	COG0154	amidase activity
GMBLW1_42180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GMBLW1_42350	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_42390	COG1404	Belongs to the peptidase S8 family
GMBLW1_42400	COG0284	orotidine-5'-phosphate decarboxylase activity
GMBLW1_42430	COG0515	serine threonine protein kinase
GMBLW1_42450	COG0511	ligase activity, forming carbon-carbon bonds
GMBLW1_42460	COG0439	Biotin carboxylase
GMBLW1_42540	COG0626	cystathionine gamma-synthase activity
GMBLW1_42580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_42620	COG1131	(ABC) transporter
GMBLW1_42690	COG0069	glutamate synthase activity
GMBLW1_42690	COG0070	glutamate synthase
GMBLW1_42690	COG0067	glutamate synthase
GMBLW1_42720	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_42820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GMBLW1_42830	COG0193	aminoacyl-tRNA hydrolase activity
GMBLW1_42840	COG0360	Binds together with S18 to 16S ribosomal RNA
GMBLW1_42860	COG0359	binds to the 23S rRNA
GMBLW1_42870	COG0305	Participates in initiation and elongation during chromosome replication
GMBLW1_42880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GMBLW1_42890	COG0215	cysteine-tRNA ligase activity
GMBLW1_42900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GMBLW1_42910	COG0632	four-way junction helicase activity
GMBLW1_42920	COG2255	four-way junction helicase activity
GMBLW1_42930	COG0640	Transcriptional regulator
GMBLW1_42970	COG3831	ATPase activity
GMBLW1_42970	COG4884	unkown
GMBLW1_42980	COG2271	Major facilitator Superfamily
GMBLW1_42990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GMBLW1_43010	COG2165	general secretion pathway protein
GMBLW1_43180	COG1051	belongs to the nudix hydrolase family
GMBLW1_43220	COG0598	Magnesium transport protein CorA
GMBLW1_43260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GMBLW1_43280	COG3046	protein related to deoxyribodipyrimidine photolyase
GMBLW1_43320	COG0322	excinuclease ABC activity
GMBLW1_43330	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GMBLW1_43340	COG1480	7TM receptor with intracellular HD hydrolase
GMBLW1_43350	COG1702	phosphate starvation-inducible protein PhoH
GMBLW1_43360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMBLW1_43360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMBLW1_43360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMBLW1_43380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GMBLW1_43410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GMBLW1_43510	COG0300	oxidoreductase activity
GMBLW1_43520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GMBLW1_43550	COG3119	arylsulfatase activity
GMBLW1_43560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GMBLW1_43580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GMBLW1_43630	COG0196	riboflavin kinase activity
GMBLW1_43810	COG1959	2 iron, 2 sulfur cluster binding
GMBLW1_43830	COG0045	succinate-CoA ligase (ADP-forming) activity
GMBLW1_43850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GMBLW1_43930	COG1063	alcohol dehydrogenase
GMBLW1_43950	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GMBLW1_43980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_44070	COG0612	Peptidase, M16
GMBLW1_44080	COG0612	Peptidase, M16
GMBLW1_44530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_44550	COG0515	serine threonine protein kinase
GMBLW1_44550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMBLW1_44760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GMBLW1_44800	COG0515	serine threonine protein kinase
GMBLW1_44800	COG2815	serine threonine protein kinase
GMBLW1_44820	COG3842	ATPase activity
GMBLW1_44830	COG0285	dihydrofolate synthase activity
GMBLW1_44870	COG2815	serine threonine protein kinase
GMBLW1_44870	COG0515	serine threonine protein kinase
GMBLW1_44880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMBLW1_44890	COG2815	serine threonine protein kinase
GMBLW1_44890	COG0515	serine threonine protein kinase
GMBLW1_44910	COG2204	response regulator
GMBLW1_44920	COG0653	protein targeting
GMBLW1_44940	COG0180	Tryptophanyl-tRNA synthetase
GMBLW1_44950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMBLW1_44960	COG0047	phosphoribosylformylglycinamidine synthase activity
GMBLW1_45010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMBLW1_45040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_45070	COG0653	protein targeting
GMBLW1_45080	COG1519	Transferase
GMBLW1_45100	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMBLW1_45130	COG0673	inositol 2-dehydrogenase activity
GMBLW1_45170	COG0142	geranyltranstransferase activity
GMBLW1_45240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_45450	COG0517	IMP dehydrogenase activity
GMBLW1_45480	COG0823	Involved in the tonB-independent uptake of proteins
GMBLW1_45500	COG4969	Belongs to the N-Me-Phe pilin family
GMBLW1_45510	COG0259	pyridoxamine-phosphate oxidase activity
GMBLW1_45530	COG2308	Evidence 4 Homologs of previously reported genes of
GMBLW1_45540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GMBLW1_45560	COG1131	(ABC) transporter
GMBLW1_45680	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GMBLW1_45690	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GMBLW1_45700	COG0515	serine threonine protein kinase
GMBLW1_45700	COG2815	serine threonine protein kinase
GMBLW1_45730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GMBLW1_45760	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GMBLW1_45810	COG0842	Transport permease protein
GMBLW1_45810	COG1716	ATPase activity
GMBLW1_45810	COG1131	(ABC) transporter
GMBLW1_45890	COG1192	Involved in chromosome partitioning
GMBLW1_45900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GMBLW1_45920	COG0515	serine threonine protein kinase
GMBLW1_45950	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GMBLW1_45970	COG0602	queuosine metabolic process
GMBLW1_45980	COG0673	inositol 2-dehydrogenase activity
GMBLW1_45990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GMBLW1_46070	COG0009	L-threonylcarbamoyladenylate synthase
GMBLW1_46080	COG0531	amino acid
GMBLW1_46100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_46140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GMBLW1_46300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GMBLW1_46330	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_46370	COG1333	cytochrome c biogenesis protein
GMBLW1_46370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GMBLW1_46430	COG0714	Associated with various cellular activities
GMBLW1_46440	COG0673	inositol 2-dehydrogenase activity
GMBLW1_46450	COG2226	methyltransferase
GMBLW1_46470	COG1012	belongs to the aldehyde dehydrogenase family
GMBLW1_46510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GMBLW1_46520	COG0527	aspartate kinase activity
GMBLW1_46540	COG0116	Belongs to the methyltransferase superfamily
GMBLW1_46540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMBLW1_46560	COG1902	pentaerythritol trinitrate reductase activity
GMBLW1_46640	COG0386	Belongs to the glutathione peroxidase family
GMBLW1_46650	COG1595	DNA-templated transcription, initiation
GMBLW1_46710	COG1595	DNA-templated transcription, initiation
GMBLW1_46740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMBLW1_46810	COG1028	Short-chain dehydrogenase reductase Sdr
GMBLW1_46830	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GMBLW1_46840	COG2207	Transcriptional regulator
GMBLW1_46850	COG1064	alcohol dehydrogenase
GMBLW1_46870	COG3541	Predicted nucleotidyltransferase
GMBLW1_46880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GMBLW1_46900	COG0793	Belongs to the peptidase S41A family
GMBLW1_46920	COG2409	Drug exporters of the RND superfamily
GMBLW1_47020	COG1819	glycosyl
GMBLW1_47040	COG0709	Synthesizes selenophosphate from selenide and ATP
GMBLW1_47050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GMBLW1_47060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GMBLW1_47070	COG0154	amidase activity
GMBLW1_47080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GMBLW1_47110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GMBLW1_47110	COG4797	methyltransferase
GMBLW1_47130	COG1595	DNA-templated transcription, initiation
GMBLW1_47140	COG0724	RNA recognition motif
GMBLW1_47150	COG2096	Adenosyltransferase
GMBLW1_47170	COG2226	methyltransferase
GMBLW1_47250	COG0793	Belongs to the peptidase S41A family
GMBLW1_47270	COG1082	Xylose isomerase domain protein TIM barrel
GMBLW1_47290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GMBLW1_47300	COG2226	methyltransferase
GMBLW1_47320	COG0006	proline dipeptidase activity
GMBLW1_47350	COG0438	transferase activity, transferring glycosyl groups
GMBLW1_47380	COG0475	glutathione-regulated potassium exporter activity
GMBLW1_47420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMBLW1_47450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMBLW1_47460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMBLW1_47500	COG0515	serine threonine protein kinase
GMBLW1_47520	COG2738	Putative neutral zinc metallopeptidase
GMBLW1_47530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMBLW1_47530	COG0515	serine threonine protein kinase
GMBLW1_47570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMBLW1_47600	COG1940	carbohydrate kinase activity
GMBLW1_47610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMBLW1_47630	COG0612	Peptidase, M16
GMBLW1_47770	COG0217	transcriptional regulatory protein
GMBLW1_47800	COG1032	radical SAM domain protein
GMBLW1_47820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMBLW1_47950	COG1331	Highly conserved protein containing a thioredoxin domain
GMBLW1_47960	COG0515	serine threonine protein kinase
GMBLW1_47960	COG2815	serine threonine protein kinase
GMBLW1_48030	COG4208	sulfate ABC transporter
GMBLW1_48040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GMBLW1_48060	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GMBLW1_48070	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GMBLW1_48090	COG1122	ATPase activity
GMBLW1_48120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMBLW1_48150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GMBLW1_48170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GMBLW1_48200	COG0588	phosphoglycerate mutase activity
GMBLW1_48230	COG3119	arylsulfatase activity
GMBLW1_48260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GMBLW1_48270	COG1233	COG1233 Phytoene dehydrogenase and related
GMBLW1_48360	COG0515	serine threonine protein kinase
GMBLW1_48360	COG2815	serine threonine protein kinase
GMBLW1_48390	COG1216	Glycosyl transferase, family 2
GMBLW1_48410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_48470	COG0750	zinc metalloprotease
GMBLW1_48480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GMBLW1_48540	COG1121	(ABC) transporter
GMBLW1_48570	COG1473	amidohydrolase
GMBLW1_48580	COG0463	Glycosyl transferase, family 2
GMBLW1_48600	COG0515	serine threonine protein kinase
GMBLW1_48640	COG2815	serine threonine protein kinase
GMBLW1_48640	COG0515	serine threonine protein kinase
GMBLW1_48670	COG1192	Involved in chromosome partitioning
GMBLW1_48740	COG2205	protein histidine kinase activity
GMBLW1_48740	COG3437	response regulator, receiver
GMBLW1_48740	COG3850	Histidine kinase
GMBLW1_48740	COG4999	Histidine kinase
GMBLW1_48880	COG4956	integral membrane protein (PIN domain superfamily)
GMBLW1_48890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GMBLW1_48910	COG0416	fatty acid biosynthetic process
GMBLW1_48920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMBLW1_48930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMBLW1_48940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMBLW1_48980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_48990	COG1136	(ABC) transporter
GMBLW1_49070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GMBLW1_49110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMBLW1_49190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMBLW1_49210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMBLW1_49230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMBLW1_49280	COG2154	pterin-4-alpha-carbinolamine dehydratase
GMBLW1_49310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GMBLW1_49370	COG5002	protein histidine kinase activity
GMBLW1_49380	COG2205	protein histidine kinase activity
GMBLW1_49630	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GMBLW1_49650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMBLW1_49680	COG1040	competence protein
GMBLW1_49720	COG0445	tRNA wobble uridine modification
GMBLW1_49730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMBLW1_49740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GMBLW1_49830	COG0515	serine threonine protein kinase
GMBLW1_49830	COG2815	serine threonine protein kinase
GMBLW1_49840	COG3179	chitinase
GMBLW1_49870	COG1088	dTDP-glucose 4,6-dehydratase activity
GMBLW1_49900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GMBLW1_49910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMBLW1_49990	COG1216	Glycosyl transferase, family 2
GMBLW1_50000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GMBLW1_50010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GMBLW1_50030	COG1418	mRNA catabolic process
GMBLW1_50040	COG1692	metallophosphoesterase
GMBLW1_50050	COG0405	Gamma-glutamyltransferase
GMBLW1_50070	COG0205	6-phosphofructokinase activity
GMBLW1_50090	COG0443	Heat shock 70 kDa protein
GMBLW1_50100	COG1605	Chorismate mutase
GMBLW1_50100	COG0077	Prephenate dehydratase
GMBLW1_50110	COG0149	triose-phosphate isomerase activity
GMBLW1_50130	COG1561	YicC-like family, N-terminal region
GMBLW1_50150	COG1758	RNA polymerase activity
GMBLW1_50180	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GMBLW1_50230	COG4946	Tricorn protease homolog
GMBLW1_50230	COG0793	Belongs to the peptidase S41A family
GMBLW1_50250	COG2115	Belongs to the xylose isomerase family
GMBLW1_50260	COG0693	protein deglycase activity
GMBLW1_50270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMBLW1_50280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMBLW1_50300	COG1137	ATPase activity
GMBLW1_50380	COG4968	Prepilin-type N-terminal cleavage methylation domain
GMBLW1_50420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GMBLW1_50430	COG1131	(ABC) transporter
GMBLW1_50480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMBLW1_50540	COG0714	Associated with various cellular activities
GMBLW1_50610	COG0300	oxidoreductase activity
GMBLW1_50650	COG2815	serine threonine protein kinase
GMBLW1_50650	COG0515	serine threonine protein kinase
GMBLW1_50680	COG0154	amidase activity
GMBLW1_50750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMBLW1_50810	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GMBLW1_50830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMBLW1_50840	COG0525	valine-tRNA ligase activity
GMBLW1_50850	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GMBLW1_50860	COG0583	DNA-binding transcription factor activity
GMBLW1_50890	COG1446	asparaginase
GMBLW1_50920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GMBLW1_51030	COG0523	cobalamin synthesis protein
GMBLW1_51040	COG2319	Wd-40 repeat
GMBLW1_51040	COG5635	Nacht domain
GMBLW1_51050	COG0564	pseudouridine synthase activity
GMBLW1_51070	COG1301	dicarboxylic acid transport
GMBLW1_51080	COG1858	cytochrome C peroxidase
GMBLW1_51100	COG2076	Multidrug Resistance protein
GMBLW1_51140	COG0714	Associated with various cellular activities
GMBLW1_51220	COG2201	protein-glutamate methylesterase activity
GMBLW1_51240	COG4251	negative regulation of phosphorylation
GMBLW1_51250	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GMBLW1_51260	COG2205	protein histidine kinase activity
GMBLW1_51280	COG0450	alkyl hydroperoxide reductase
GMBLW1_51290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GMBLW1_51370	COG0488	(ABC) transporter
GMBLW1_51430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GMBLW1_51480	COG2815	serine threonine protein kinase
GMBLW1_51480	COG0515	serine threonine protein kinase
GMBLW1_51510	COG0579	oxidoreductase
GMBLW1_51520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMBLW1_51520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMBLW1_51590	COG0363	glucosamine-6-phosphate deaminase activity
GMBLW1_51600	COG2022	thiamine diphosphate biosynthetic process
GMBLW1_51640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMBLW1_51680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GMBLW1_51730	COG2815	serine threonine protein kinase
GMBLW1_51730	COG0515	serine threonine protein kinase
GMBLW1_51740	COG3386	PFAM SMP-30 Gluconolaconase
GMBLW1_51800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GMBLW1_51840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMBLW1_51860	COG0585	pseudouridine synthase activity
GMBLW1_51900	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GMBLW1_51910	COG1518	maintenance of DNA repeat elements
GMBLW1_51960	COG3119	arylsulfatase activity
GMBLW1_52390	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GMBLW1_52500	COG4712	double-strand break repair protein
GMBLW1__T560	COG0544	peptidyl-prolyl cis-trans isomerase activity