locus-tag	class	description
ETAA1_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA1_00110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETAA1_00130	COG0475	glutathione-regulated potassium exporter activity
ETAA1_00140	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ETAA1_00150	COG1846	Transcriptional regulator
ETAA1_00210	COG1475	DNA binding
ETAA1_00230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETAA1_00230	COG1796	DNA polymerase
ETAA1_00240	COG0436	Aminotransferase
ETAA1_00290	COG0724	RNA recognition motif
ETAA1_00300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA1_00350	COG5487	UPF0391 membrane protein
ETAA1_00420	COG4912	Dna alkylation repair
ETAA1_00450	COG0745	RESPONSE REGULATOR receiver
ETAA1_00460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA1_00490	COG3485	protocatechuate 3,4-dioxygenase
ETAA1_00510	COG2816	NAD+ diphosphatase activity
ETAA1_00520	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA1_00570	COG0004	ammonium transporteR
ETAA1_00610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA1_00640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETAA1_00660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETAA1_00680	COG0515	serine threonine protein kinase
ETAA1_00680	COG2815	serine threonine protein kinase
ETAA1_00690	COG2271	Major facilitator Superfamily
ETAA1_00770	COG1196	nuclear chromosome segregation
ETAA1_00780	COG1706	bacterial-type flagellum-dependent cell motility
ETAA1_00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA1_00800	COG1459	type II secretion system
ETAA1_00890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETAA1_00930	COG0358	DNA primase activity
ETAA1_00940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA1_00980	COG1131	(ABC) transporter
ETAA1_01000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETAA1_01040	COG0640	Transcriptional regulator
ETAA1_01070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETAA1_01090	COG3069	C4-dicarboxylate transmembrane transporter activity
ETAA1_01120	COG0277	FAD linked oxidase domain protein
ETAA1_01130	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_01160	COG2832	Protein of unknown function (DUF454)
ETAA1_01180	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA1_01270	COG1404	Belongs to the peptidase S8 family
ETAA1_01300	COG4303	Ethanolamine ammonia lyase large subunit
ETAA1_01360	COG1132	(ABC) transporter
ETAA1_01370	COG4106	trans-aconitate 2-methyltransferase activity
ETAA1_01390	COG0688	phosphatidylethanolamine metabolic process
ETAA1_01420	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ETAA1_01430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA1_01480	COG5002	protein histidine kinase activity
ETAA1_01480	COG0784	Response regulator, receiver
ETAA1_01500	COG0745	RESPONSE REGULATOR receiver
ETAA1_01580	COG0628	permease
ETAA1_01590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETAA1_01640	COG0667	Aldo Keto reductase
ETAA1_01650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ETAA1_01720	COG2084	Dehydrogenase
ETAA1_01780	COG0594	ribonuclease P activity
ETAA1_01790	COG0484	heat shock protein binding
ETAA1_01840	COG0534	Mate efflux family protein
ETAA1_01860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_01900	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA1_01980	COG0045	succinate-CoA ligase (ADP-forming) activity
ETAA1_02040	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA1_02070	COG0006	proline dipeptidase activity
ETAA1_02210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_02220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETAA1_02230	COG3002	Belongs to the UPF0753 family
ETAA1_02240	COG4191	Histidine kinase
ETAA1_02260	COG0659	secondary active sulfate transmembrane transporter activity
ETAA1_02270	COG3876	Protein conserved in bacteria
ETAA1_02290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ETAA1_02320	COG1595	DNA-templated transcription, initiation
ETAA1_02330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA1_02380	COG0657	acetylesterase activity
ETAA1_02410	COG1674	ftsk spoiiie
ETAA1_02410	COG4980	gas vesicle protein
ETAA1_02420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETAA1_02450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_02480	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA1_02530	COG0295	cytidine deaminase activity
ETAA1_02540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA1_02590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_02630	COG4221	oxidoreductase activity
ETAA1_02650	COG1940	carbohydrate kinase activity
ETAA1_02690	COG0484	heat shock protein binding
ETAA1_02740	COG0443	Heat shock 70 kDa protein
ETAA1_02760	COG2373	Large extracellular alpha-helical protein
ETAA1_02780	COG0515	serine threonine protein kinase
ETAA1_02800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETAA1_02810	COG1082	Xylose isomerase domain protein TIM barrel
ETAA1_02820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETAA1_03000	COG0564	pseudouridine synthase activity
ETAA1_03030	COG1984	allophanate hydrolase subunit 2
ETAA1_03050	COG0436	Aminotransferase
ETAA1_03060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_03070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_03080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_03090	COG0649	NAD binding
ETAA1_03110	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ETAA1_03150	COG1034	ATP synthesis coupled electron transport
ETAA1_03160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA1_03170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_03180	COG0839	Belongs to the complex I subunit 6 family
ETAA1_03190	COG0713	ATP synthesis coupled electron transport
ETAA1_03200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETAA1_03220	COG1007	ATP synthesis coupled electron transport
ETAA1_03360	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA1_03370	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA1_03370	COG1013	pyruvate-flavodoxin oxidoreductase activity
ETAA1_03370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ETAA1_03370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_03650	COG1002	Type II restriction enzyme, methylase subunits
ETAA1_03760	COG0463	Glycosyl transferase, family 2
ETAA1_03770	COG0275	rRNA processing
ETAA1_03820	COG0714	Associated with various cellular activities
ETAA1_03840	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ETAA1_03870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETAA1_03900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA1_03960	COG2072	flavoprotein involved in K transport
ETAA1_04010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA1_04020	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ETAA1_04030	COG0702	epimerase
ETAA1_04040	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_04080	COG3046	protein related to deoxyribodipyrimidine photolyase
ETAA1_04090	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ETAA1_04110	COG0515	serine threonine protein kinase
ETAA1_04110	COG2815	serine threonine protein kinase
ETAA1_04120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETAA1_04150	COG4964	Belongs to the GSP D family
ETAA1_04220	COG0740	serine-type endopeptidase activity
ETAA1_04230	COG0740	serine-type endopeptidase activity
ETAA1_04240	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETAA1_04260	COG0776	regulation of translation
ETAA1_04340	COG2165	general secretion pathway protein
ETAA1_04420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_04440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETAA1_04540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_04550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETAA1_04640	COG4964	Belongs to the GSP D family
ETAA1_04720	COG0457	Tetratricopeptide repeat
ETAA1_04820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA1_04880	COG0438	transferase activity, transferring glycosyl groups
ETAA1_04890	COG0443	Heat shock 70 kDa protein
ETAA1_04960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA1_04970	COG0577	efflux transmembrane transporter activity
ETAA1_04970	COG1136	(ABC) transporter
ETAA1_04980	COG1136	(ABC) transporter
ETAA1_05000	COG0488	(ABC) transporter
ETAA1_05010	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ETAA1_05100	COG0022	dehydrogenase e1 component
ETAA1_05110	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETAA1_05130	COG1335	isochorismatase
ETAA1_05140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_05170	COG0359	binds to the 23S rRNA
ETAA1_05190	COG0360	Binds together with S18 to 16S ribosomal RNA
ETAA1_05220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETAA1_05250	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA1_05270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ETAA1_05280	COG3186	Phenylalanine-4-hydroxylase
ETAA1_05290	COG0604	alcohol dehydrogenase
ETAA1_05350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETAA1_05420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA1_05470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA1_05500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA1_05520	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA1_05530	COG2205	protein histidine kinase activity
ETAA1_05530	COG0784	Response regulator, receiver
ETAA1_05550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETAA1_05560	COG1137	ATPase activity
ETAA1_05580	COG2268	Band 7 protein
ETAA1_05720	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA1_05740	COG1215	transferase activity, transferring glycosyl groups
ETAA1_05840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETAA1_05880	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETAA1_05890	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ETAA1_06000	COG0673	inositol 2-dehydrogenase activity
ETAA1_06040	COG1760	l-serine dehydratase
ETAA1_06060	COG2204	response regulator
ETAA1_06140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA1_06150	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA1_06170	COG3383	formate dehydrogenase (NAD+) activity
ETAA1_06180	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ETAA1_06240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA1_06260	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA1_06280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA1_06290	COG0509	glycine decarboxylation via glycine cleavage system
ETAA1_06300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA1_06520	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA1_06560	COG0439	Biotin carboxylase
ETAA1_06570	COG0511	ligase activity, forming carbon-carbon bonds
ETAA1_06580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA1_06590	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETAA1_06600	COG1649	PFAM Uncharacterised BCR, COG1649
ETAA1_06740	COG0579	oxidoreductase
ETAA1_06750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ETAA1_06840	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA1_06860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA1_06870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETAA1_06880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETAA1_06970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETAA1_07000	COG1131	(ABC) transporter
ETAA1_07040	COG0181	hydroxymethylbilane synthase activity
ETAA1_07050	COG1119	ATPase activity
ETAA1_07060	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_07060	COG1506	peptidase
ETAA1_07110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_07120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_07140	COG0826	peptidase U32
ETAA1_07210	COG2815	serine threonine protein kinase
ETAA1_07210	COG0515	serine threonine protein kinase
ETAA1_07230	COG0438	transferase activity, transferring glycosyl groups
ETAA1_07320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETAA1_07330	COG0673	inositol 2-dehydrogenase activity
ETAA1_07350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETAA1_07370	COG2815	serine threonine protein kinase
ETAA1_07370	COG0515	serine threonine protein kinase
ETAA1_07460	COG1214	PFAM Peptidase M22, glycoprotease
ETAA1_07580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETAA1_07670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA1_07670	COG4797	methyltransferase
ETAA1_07680	COG0569	domain protein
ETAA1_07680	COG0475	glutathione-regulated potassium exporter activity
ETAA1_07720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA1_07730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETAA1_07850	COG3224	Antibiotic biosynthesis monooxygenase
ETAA1_07890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETAA1_07920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA1_07970	COG0411	ABC transporter
ETAA1_07990	COG0559	Belongs to the binding-protein-dependent transport system permease family
ETAA1_08010	COG1490	D-aminoacyl-tRNA deacylase activity
ETAA1_08060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETAA1_08070	COG1082	Xylose isomerase domain protein TIM barrel
ETAA1_08100	COG0673	inositol 2-dehydrogenase activity
ETAA1_08110	COG0284	orotidine-5'-phosphate decarboxylase activity
ETAA1_08130	COG1073	alpha beta
ETAA1_08160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA1_08180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA1_08180	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ETAA1_08190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA1_08200	COG0515	serine threonine protein kinase
ETAA1_08200	COG2815	serine threonine protein kinase
ETAA1_08290	COG3344	reverse transcriptase
ETAA1_08430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_08550	COG4372	Transposase
ETAA1_08570	COG2815	serine threonine protein kinase
ETAA1_08570	COG0515	serine threonine protein kinase
ETAA1_08760	COG0714	Associated with various cellular activities
ETAA1_08840	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ETAA1_09340	COG0217	transcriptional regulatory protein
ETAA1_09350	COG3119	arylsulfatase activity
ETAA1_09360	COG3119	arylsulfatase activity
ETAA1_09380	COG0017	Asparaginyl-tRNA synthetase
ETAA1_09430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA1_09470	COG0585	pseudouridine synthase activity
ETAA1_09590	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ETAA1_09610	COG0463	Glycosyl transferase, family 2
ETAA1_09650	COG0167	dihydroorotate dehydrogenase activity
ETAA1_09660	COG1131	(ABC) transporter
ETAA1_09680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETAA1_09690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA1_09700	COG0793	Belongs to the peptidase S41A family
ETAA1_09720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA1_09730	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA1_09840	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_09840	COG1506	peptidase
ETAA1_09850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ETAA1_09880	COG2610	gluconate transmembrane transporter activity
ETAA1_09940	COG4946	Tricorn protease homolog
ETAA1_09940	COG1506	peptidase
ETAA1_09940	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_09950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETAA1_09990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA1_10070	COG0463	Glycosyl transferase, family 2
ETAA1_10110	COG0514	ATP-dependent DNA helicase (RecQ)
ETAA1_10130	COG2271	Major facilitator Superfamily
ETAA1_10150	COG1401	restriction endodeoxyribonuclease activity
ETAA1_10180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA1_10210	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ETAA1_10220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA1_10370	COG0163	prenyltransferase activity
ETAA1_10410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETAA1_10430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETAA1_10450	COG0653	protein targeting
ETAA1_10460	COG0423	glycine-tRNA ligase activity
ETAA1_10480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ETAA1_10560	COG1166	arginine decarboxylase activity
ETAA1_10620	COG0515	serine threonine protein kinase
ETAA1_10620	COG2815	serine threonine protein kinase
ETAA1_10660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETAA1_10670	COG2226	methyltransferase
ETAA1_10690	COG0006	proline dipeptidase activity
ETAA1_10760	COG2096	Adenosyltransferase
ETAA1_10790	COG0012	GTP binding
ETAA1_10810	COG4636	protein conserved in cyanobacteria
ETAA1_10870	COG3540	Alkaline phosphatase
ETAA1_10890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_10900	COG1304	FMN binding
ETAA1_10940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETAA1_10970	COG0673	inositol 2-dehydrogenase activity
ETAA1_11010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ETAA1_11060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA1_11070	COG0583	DNA-binding transcription factor activity
ETAA1_11110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETAA1_11140	COG4974	Belongs to the 'phage' integrase family
ETAA1_11160	COG0363	glucosamine-6-phosphate deaminase activity
ETAA1_11180	COG0515	serine threonine protein kinase
ETAA1_11180	COG2815	serine threonine protein kinase
ETAA1_11240	COG1312	Catalyzes the dehydration of D-mannonate
ETAA1_11270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA1_11340	COG0673	inositol 2-dehydrogenase activity
ETAA1_11350	COG2271	Major facilitator Superfamily
ETAA1_11400	COG3059	membrane
ETAA1_11480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETAA1_11480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETAA1_11540	COG5002	protein histidine kinase activity
ETAA1_11570	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_11600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA1_11680	COG1477	protein flavinylation
ETAA1_11810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETAA1_11820	COG0799	negative regulation of ribosome biogenesis
ETAA1_11830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA1_11850	COG0305	Participates in initiation and elongation during chromosome replication
ETAA1_11890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETAA1_11900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_11940	COG0528	UMP kinase activity
ETAA1_11950	COG0233	cytoplasmic translational termination
ETAA1_11960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA1_12100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETAA1_12130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETAA1_12180	COG0673	inositol 2-dehydrogenase activity
ETAA1_12200	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETAA1_12240	COG3781	membrane
ETAA1_12290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETAA1_12320	COG0322	excinuclease ABC activity
ETAA1_12480	COG0515	serine threonine protein kinase
ETAA1_12480	COG2815	serine threonine protein kinase
ETAA1_12490	COG0095	Lipoate-protein ligase
ETAA1_12510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA1_12510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA1_12580	COG3386	PFAM SMP-30 Gluconolaconase
ETAA1_12650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETAA1_12670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETAA1_12690	COG0724	RNA recognition motif
ETAA1_12700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETAA1_12720	COG3228	Belongs to the MtfA family
ETAA1_12740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA1_12930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETAA1_12950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA1_13020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ETAA1_13140	COG2815	serine threonine protein kinase
ETAA1_13140	COG0515	serine threonine protein kinase
ETAA1_13150	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
ETAA1_13170	COG0515	serine threonine protein kinase
ETAA1_13180	COG0457	Tetratricopeptide repeat
ETAA1_13180	COG0515	serine threonine protein kinase
ETAA1_13190	COG0667	Aldo Keto reductase
ETAA1_13230	COG1668	transmembrane transport
ETAA1_13250	COG0277	FAD linked oxidase domain protein
ETAA1_13300	COG4191	Histidine kinase
ETAA1_13310	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ETAA1_13390	COG2204	response regulator
ETAA1_13400	COG4191	Histidine kinase
ETAA1_13480	COG3119	arylsulfatase activity
ETAA1_13490	COG3119	arylsulfatase activity
ETAA1_13620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_13620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_13760	COG4232	protein-disulfide reductase activity
ETAA1_13780	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETAA1_13830	COG1185	polyribonucleotide nucleotidyltransferase activity
ETAA1_13880	COG1358	cellular component organization or biogenesis
ETAA1_13980	COG0673	inositol 2-dehydrogenase activity
ETAA1_14000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETAA1_14110	COG0582	viral genome integration into host DNA
ETAA1_14230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ETAA1_14270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA1_14290	COG0463	Glycosyl transferase, family 2
ETAA1_14380	COG0714	Associated with various cellular activities
ETAA1_14460	COG0737	Belongs to the 5'-nucleotidase family
ETAA1_14510	COG1295	ribonuclease BN
ETAA1_14530	COG5487	UPF0391 membrane protein
ETAA1_14550	COG2205	protein histidine kinase activity
ETAA1_14590	COG0515	serine threonine protein kinase
ETAA1_14690	COG2226	methyltransferase
ETAA1_14810	COG1741	Belongs to the pirin family
ETAA1_14900	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA1_14900	COG0204	Acyl-transferase
ETAA1_14950	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ETAA1_14980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETAA1_14990	COG0484	heat shock protein binding
ETAA1_15000	COG0459	protein refolding
ETAA1_15010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA1_15020	COG0459	protein refolding
ETAA1_15040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETAA1_15080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETAA1_15160	COG1519	Transferase
ETAA1_15180	COG4191	Histidine kinase
ETAA1_15260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_15270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETAA1_15280	COG0022	dehydrogenase e1 component
ETAA1_15330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA1_15350	COG2258	MOSC domain
ETAA1_15420	COG1595	DNA-templated transcription, initiation
ETAA1_15430	COG3481	metal-dependent phosphohydrolase, HD sub domain
ETAA1_15460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ETAA1_15470	COG0398	Pfam SNARE associated Golgi protein
ETAA1_15500	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA1_15570	COG0745	RESPONSE REGULATOR receiver
ETAA1_15600	COG3119	arylsulfatase activity
ETAA1_15780	COG0861	Integral membrane protein TerC family
ETAA1_15800	COG0800	Aldolase
ETAA1_15820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA1_15830	COG0154	amidase activity
ETAA1_15870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETAA1_15890	COG0653	protein targeting
ETAA1_15900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA1_15900	COG2755	lipolytic protein G-D-S-L family
ETAA1_15970	COG2135	peptidase activity
ETAA1_16070	COG0724	RNA recognition motif
ETAA1_16150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETAA1_16160	COG2226	methyltransferase
ETAA1_16170	COG1555	photosystem II stabilization
ETAA1_16280	COG1560	Kdo2-lipid A biosynthetic process
ETAA1_16290	COG0730	response to heat
ETAA1_16300	COG2827	Endonuclease containing a URI domain
ETAA1_16340	COG1073	alpha beta
ETAA1_16390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETAA1_16460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA1_16520	COG2304	oxidoreductase activity
ETAA1_16630	COG0724	RNA recognition motif
ETAA1_16650	COG0724	RNA recognition motif
ETAA1_16770	COG2176	DNA-directed DNA polymerase activity
ETAA1_16770	COG5002	protein histidine kinase activity
ETAA1_16870	COG3344	reverse transcriptase
ETAA1_16880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETAA1_16960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_16960	COG0515	serine threonine protein kinase
ETAA1_17360	COG2801	Transposase and inactivated derivatives
ETAA1_17460	COG0217	transcriptional regulatory protein
ETAA1_17550	COG4372	Transposase
ETAA1_17600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_18240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA1_18250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ETAA1_18280	COG1088	dTDP-glucose 4,6-dehydratase activity
ETAA1_18310	COG2226	methyltransferase
ETAA1_18320	COG3958	Transketolase
ETAA1_18330	COG3959	Transketolase, thiamine diphosphate binding domain
ETAA1_18340	COG1215	transferase activity, transferring glycosyl groups
ETAA1_18350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA1_18360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETAA1_18360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ETAA1_18390	COG0189	ligase activity
ETAA1_18410	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
ETAA1_18450	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_18470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETAA1_18500	COG0577	efflux transmembrane transporter activity
ETAA1_18540	COG2271	Major facilitator Superfamily
ETAA1_18570	COG1122	ATPase activity
ETAA1_18590	COG1410	methionine synthase
ETAA1_18590	COG0646	methionine synthase
ETAA1_18610	COG1121	(ABC) transporter
ETAA1_18620	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETAA1_18650	COG0515	serine threonine protein kinase
ETAA1_18650	COG2815	serine threonine protein kinase
ETAA1_18660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA1_18670	COG1640	4-alpha-glucanotransferase
ETAA1_18720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETAA1_18860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ETAA1_18900	COG1136	(ABC) transporter
ETAA1_18900	COG0577	efflux transmembrane transporter activity
ETAA1_19000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA1_19030	COG2819	hydrolase of the alpha beta superfamily
ETAA1_19070	COG2154	pterin-4-alpha-carbinolamine dehydratase
ETAA1_19080	COG2308	Evidence 4 Homologs of previously reported genes of
ETAA1_19170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETAA1_19180	COG0148	phosphopyruvate hydratase activity
ETAA1_19200	COG1247	-acetyltransferase
ETAA1_19220	COG0300	oxidoreductase activity
ETAA1_19230	COG0497	DNA recombination
ETAA1_19390	COG0515	serine threonine protein kinase
ETAA1_19390	COG2815	serine threonine protein kinase
ETAA1_19400	COG2770	Histidine kinase
ETAA1_19400	COG2208	phosphoserine phosphatase activity
ETAA1_19440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA1_19500	COG1454	alcohol dehydrogenase
ETAA1_19560	COG1012	belongs to the aldehyde dehydrogenase family
ETAA1_19570	COG0515	serine threonine protein kinase
ETAA1_19570	COG2815	serine threonine protein kinase
ETAA1_19610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA1_19640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETAA1_19660	COG0612	Peptidase, M16
ETAA1_19760	COG2234	aminopeptidase activity
ETAA1_19800	COG2319	Wd-40 repeat
ETAA1_19810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETAA1_19840	COG1199	ATP-dependent helicase activity
ETAA1_19860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETAA1_19880	COG1215	transferase activity, transferring glycosyl groups
ETAA1_19900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_19910	COG1858	cytochrome C peroxidase
ETAA1_19940	COG0277	FAD linked oxidase domain protein
ETAA1_19950	COG0247	lactate metabolic process
ETAA1_20020	COG0545	Peptidyl-prolyl cis-trans isomerase
ETAA1_20030	COG0545	Peptidyl-prolyl cis-trans isomerase
ETAA1_20040	COG1253	flavin adenine dinucleotide binding
ETAA1_20070	COG0438	transferase activity, transferring glycosyl groups
ETAA1_20110	COG0489	protein tyrosine kinase activity
ETAA1_20150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_20160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETAA1_20220	COG0137	argininosuccinate synthase activity
ETAA1_20230	COG0424	maF-like protein
ETAA1_20260	COG0742	ribosomal rna small subunit methyltransferase
ETAA1_20320	COG4762	Protein conserved in bacteria
ETAA1_20390	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETAA1_20450	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_20630	COG2204	response regulator
ETAA1_20640	COG2205	protein histidine kinase activity
ETAA1_20690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA1_20710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETAA1_20720	COG0022	dehydrogenase e1 component
ETAA1_20780	COG0473	3-isopropylmalate dehydrogenase activity
ETAA1_20810	COG0028	Belongs to the TPP enzyme family
ETAA1_20830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETAA1_20890	COG1606	tRNA processing
ETAA1_20900	COG0589	response to stress
ETAA1_20940	COG0037	tRNA processing
ETAA1_20950	COG0138	bifunctional purine biosynthesis protein purh
ETAA1_20960	COG1363	Peptidase, m42
ETAA1_21000	COG0463	Glycosyl transferase, family 2
ETAA1_21020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA1_21050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_21060	COG0443	Heat shock 70 kDa protein
ETAA1_21090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ETAA1_21120	COG1104	cysteine desulfurase activity
ETAA1_21150	COG0617	tRNA 3'-terminal CCA addition
ETAA1_21160	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ETAA1_21190	COG0131	Imidazoleglycerol-phosphate dehydratase
ETAA1_21200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETAA1_21210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETAA1_21240	COG1858	cytochrome C peroxidase
ETAA1_21280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETAA1_21400	COG0203	ribosomal protein L17
ETAA1_21410	COG0202	RNA polymerase activity
ETAA1_21420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETAA1_21430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETAA1_21440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETAA1_21460	COG0024	Methionine aminopeptidase
ETAA1_21470	COG0201	protein transport
ETAA1_21490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETAA1_21500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETAA1_21510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETAA1_21520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETAA1_21530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETAA1_21540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETAA1_21550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ETAA1_21560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETAA1_21570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETAA1_21580	COG0255	Belongs to the universal ribosomal protein uL29 family
ETAA1_21590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETAA1_21600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETAA1_21610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETAA1_21620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETAA1_21630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETAA1_21640	COG0089	rRNA binding
ETAA1_21650	COG0088	Forms part of the polypeptide exit tunnel
ETAA1_21660	COG0051	transcription antitermination factor activity, RNA binding
ETAA1_21670	COG0072	phenylalanine-tRNA ligase activity
ETAA1_21670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA1_21680	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA1_21680	COG3848	Pyruvate phosphate dikinase
ETAA1_21710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA1_21720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETAA1_21780	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ETAA1_21790	COG0673	inositol 2-dehydrogenase activity
ETAA1_21800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETAA1_21850	COG0622	Phosphoesterase
ETAA1_21910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA1_21970	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA1_21970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA1_22030	COG2319	Wd-40 repeat
ETAA1_22040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETAA1_22080	COG0084	hydrolase, TatD family'
ETAA1_22120	COG0443	Heat shock 70 kDa protein
ETAA1_22130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA1_22130	COG0758	DNA mediated transformation
ETAA1_22200	COG2815	serine threonine protein kinase
ETAA1_22200	COG0515	serine threonine protein kinase
ETAA1_22210	COG2124	cytochrome p450
ETAA1_22240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ETAA1_22330	COG1968	undecaprenyl-diphosphatase activity
ETAA1_22360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ETAA1_22370	COG2205	protein histidine kinase activity
ETAA1_22390	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_22410	COG3608	succinylglutamate desuccinylase aspartoacylase
ETAA1_22440	COG1686	Belongs to the peptidase S11 family
ETAA1_22460	COG2313	pseudouridylate synthase activity
ETAA1_22470	COG0473	3-isopropylmalate dehydrogenase activity
ETAA1_22480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ETAA1_22530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETAA1_22550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA1_22560	COG1774	PSP1 C-terminal conserved region
ETAA1_22630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETAA1_22670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETAA1_22680	COG0081	regulation of translation
ETAA1_22690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETAA1_22700	COG0222	ribosome binding
ETAA1_22710	COG0085	RNA polymerase activity
ETAA1_22720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETAA1_22740	COG0049	tRNA binding
ETAA1_22750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA1_22760	COG3437	response regulator, receiver
ETAA1_22760	COG2770	Histidine kinase
ETAA1_22780	COG1012	belongs to the aldehyde dehydrogenase family
ETAA1_22840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETAA1_22870	COG3119	arylsulfatase activity
ETAA1_22880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETAA1_22910	COG0070	glutamate synthase
ETAA1_22910	COG0069	glutamate synthase activity
ETAA1_22910	COG0067	glutamate synthase
ETAA1_22930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_22940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETAA1_22950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETAA1_22970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETAA1_22990	COG0372	Belongs to the citrate synthase family
ETAA1_23030	COG0515	serine threonine protein kinase
ETAA1_23030	COG2815	serine threonine protein kinase
ETAA1_23100	COG0673	inositol 2-dehydrogenase activity
ETAA1_23130	COG0515	serine threonine protein kinase
ETAA1_23130	COG2815	serine threonine protein kinase
ETAA1_23150	COG0571	ribonuclease III activity
ETAA1_23180	COG0745	RESPONSE REGULATOR receiver
ETAA1_23200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_23240	COG1216	Glycosyl transferase, family 2
ETAA1_23240	COG0438	transferase activity, transferring glycosyl groups
ETAA1_23260	COG3119	arylsulfatase activity
ETAA1_23270	COG0347	Belongs to the P(II) protein family
ETAA1_23280	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_23370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETAA1_23370	COG0512	Glutamine amidotransferase of anthranilate synthase
ETAA1_23410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ETAA1_23410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETAA1_23420	COG0492	ferredoxin-NADP+ reductase activity
ETAA1_23430	COG4638	Rieske (2fe-2S)
ETAA1_23440	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_23470	COG1408	metallophosphoesterase
ETAA1_23500	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_23540	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_23550	COG0724	RNA recognition motif
ETAA1_23570	COG0113	porphobilinogen synthase activity
ETAA1_23640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETAA1_23710	COG2814	Major facilitator Superfamily
ETAA1_23730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_23750	COG1215	transferase activity, transferring glycosyl groups
ETAA1_23770	COG0012	GTP binding
ETAA1_23780	COG1063	alcohol dehydrogenase
ETAA1_23790	COG0515	serine threonine protein kinase
ETAA1_23790	COG2815	serine threonine protein kinase
ETAA1_23830	COG0174	glutamine synthetase
ETAA1_23850	COG0489	protein tyrosine kinase activity
ETAA1_23880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETAA1_23900	COG2204	response regulator
ETAA1_23910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETAA1_23950	COG0436	Aminotransferase
ETAA1_23970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETAA1_24000	COG4636	protein conserved in cyanobacteria
ETAA1_24010	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETAA1_24050	COG0673	inositol 2-dehydrogenase activity
ETAA1_24060	COG0596	Alpha beta hydrolase
ETAA1_24070	COG0402	S-adenosylhomocysteine deaminase activity
ETAA1_24090	COG0640	Transcriptional regulator
ETAA1_24130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETAA1_24140	COG0604	alcohol dehydrogenase
ETAA1_24140	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_24140	COG3321	synthase
ETAA1_24210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ETAA1_24230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETAA1_24240	COG1846	Transcriptional regulator
ETAA1_24390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETAA1_24430	COG0116	Belongs to the methyltransferase superfamily
ETAA1_24430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA1_24450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETAA1_24470	COG2319	Wd-40 repeat
ETAA1_24510	COG0673	inositol 2-dehydrogenase activity
ETAA1_24520	COG1312	Catalyzes the dehydration of D-mannonate
ETAA1_24530	COG0673	inositol 2-dehydrogenase activity
ETAA1_24540	COG0515	serine threonine protein kinase
ETAA1_24540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_24590	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
ETAA1_24600	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_24600	COG1506	peptidase
ETAA1_24610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETAA1_24670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ETAA1_24730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA1_24750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETAA1_24810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA1_24820	COG0052	Belongs to the universal ribosomal protein uS2 family
ETAA1_24830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETAA1_24840	COG0268	Binds directly to 16S ribosomal RNA
ETAA1_24850	COG0047	phosphoribosylformylglycinamidine synthase activity
ETAA1_24870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA1_24890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA1_24940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETAA1_24950	COG2226	methyltransferase
ETAA1_24950	COG2867	negative regulation of translational initiation
ETAA1_25600	COG0673	inositol 2-dehydrogenase activity
ETAA1_25650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETAA1_25680	COG0473	3-isopropylmalate dehydrogenase activity
ETAA1_25730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETAA1_25740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETAA1_25760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETAA1_25770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_25780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETAA1_25810	COG3119	arylsulfatase activity
ETAA1_25820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETAA1_25950	COG0673	inositol 2-dehydrogenase activity
ETAA1_26070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETAA1_26100	COG2223	nitrite transmembrane transporter activity
ETAA1_26110	COG2814	Major facilitator Superfamily
ETAA1_26210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA1_26250	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA1_26280	COG1073	alpha beta
ETAA1_26300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETAA1_26350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ETAA1_26360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETAA1_26370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETAA1_26380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETAA1_26400	COG0180	Tryptophanyl-tRNA synthetase
ETAA1_26410	COG0515	serine threonine protein kinase
ETAA1_26410	COG2815	serine threonine protein kinase
ETAA1_26430	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETAA1_26460	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA1_26580	COG0430	RNA-3'-phosphate cyclase activity
ETAA1_26650	COG1940	carbohydrate kinase activity
ETAA1_26690	COG2814	Major facilitator Superfamily
ETAA1_26710	COG2945	thiolester hydrolase activity
ETAA1_26710	COG0596	Alpha beta hydrolase
ETAA1_26760	COG1216	Glycosyl transferase, family 2
ETAA1_26760	COG0438	transferase activity, transferring glycosyl groups
ETAA1_26770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_26850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA1_26860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA1_26900	COG0515	serine threonine protein kinase
ETAA1_26900	COG2815	serine threonine protein kinase
ETAA1_26920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETAA1_27070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETAA1_27080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETAA1_27120	COG1595	DNA-templated transcription, initiation
ETAA1_27130	COG1530	ribonuclease E activity
ETAA1_27130	COG1530	ribonuclease E activity
ETAA1_27150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA1_27200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETAA1_27250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETAA1_27280	COG0107	imidazoleglycerol-phosphate synthase activity
ETAA1_27300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETAA1_27310	COG0792	nuclease activity
ETAA1_27330	COG0336	Belongs to the RNA methyltransferase TrmD family
ETAA1_27340	COG0228	four-way junction DNA binding
ETAA1_27400	COG1408	metallophosphoesterase
ETAA1_27450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ETAA1_27470	COG2239	Acts as a magnesium transporter
ETAA1_27480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETAA1_27520	COG1381	Involved in DNA repair and RecF pathway recombination
ETAA1_27570	COG0598	Magnesium transport protein CorA
ETAA1_27620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETAA1_27630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA1_27640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETAA1_27660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ETAA1_27680	COG0745	RESPONSE REGULATOR receiver
ETAA1_27720	COG1127	ABC transporter
ETAA1_27730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ETAA1_27740	COG1994	Peptidase M50
ETAA1_27750	COG0151	Belongs to the GarS family
ETAA1_27760	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETAA1_27770	COG1121	(ABC) transporter
ETAA1_27800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA1_27810	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_27820	COG0586	Pfam SNARE associated Golgi protein
ETAA1_27830	COG1802	Transcriptional regulator
ETAA1_27880	COG4191	Histidine kinase
ETAA1_27970	COG2814	Major facilitator Superfamily
ETAA1_28080	COG4589	Belongs to the CDS family
ETAA1_28120	COG0667	Aldo Keto reductase
ETAA1_28150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA1_28160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA1_28170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETAA1_28190	COG4956	integral membrane protein (PIN domain superfamily)
ETAA1_28200	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ETAA1_28240	COG0589	response to stress
ETAA1_28250	COG2264	protein methyltransferase activity
ETAA1_28270	COG2319	Wd-40 repeat
ETAA1_28330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETAA1_28370	COG0515	serine threonine protein kinase
ETAA1_28370	COG2815	serine threonine protein kinase
ETAA1_28400	COG2971	BadF BadG BcrA BcrD
ETAA1_28410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA1_28460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_28470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ETAA1_28490	COG0463	Glycosyl transferase, family 2
ETAA1_28510	COG3958	Transketolase
ETAA1_28520	COG3959	Transketolase, thiamine diphosphate binding domain
ETAA1_28540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETAA1_28570	COG0673	inositol 2-dehydrogenase activity
ETAA1_28580	COG0347	Belongs to the P(II) protein family
ETAA1_28600	COG1229	Formylmethanofuran dehydrogenase subunit A
ETAA1_28610	COG3142	Participates in the control of copper homeostasis
ETAA1_28620	COG0704	Plays a role in the regulation of phosphate uptake
ETAA1_28630	COG2815	serine threonine protein kinase
ETAA1_28630	COG0515	serine threonine protein kinase
ETAA1_28640	COG0456	acetyltransferase
ETAA1_28680	COG0612	Peptidase, M16
ETAA1_28700	COG0612	Peptidase, M16
ETAA1_28710	COG0483	inositol monophosphate 1-phosphatase activity
ETAA1_28720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETAA1_28750	COG2815	serine threonine protein kinase
ETAA1_28750	COG0515	serine threonine protein kinase
ETAA1_28760	COG2815	serine threonine protein kinase
ETAA1_28760	COG0515	serine threonine protein kinase
ETAA1_28770	COG0243	molybdopterin cofactor binding
ETAA1_28800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETAA1_28810	COG0575	Belongs to the CDS family
ETAA1_28820	COG1702	phosphate starvation-inducible protein PhoH
ETAA1_28830	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA1_28850	COG0488	(ABC) transporter
ETAA1_28890	COG1355	regulation of microtubule-based process
ETAA1_28920	COG4941	Belongs to the sigma-70 factor family
ETAA1_28950	COG0285	dihydrofolate synthase activity
ETAA1_29080	COG0306	phosphate transporter
ETAA1_29100	COG0673	inositol 2-dehydrogenase activity
ETAA1_29120	COG1477	protein flavinylation
ETAA1_29130	COG2207	Transcriptional regulator
ETAA1_29150	COG3119	arylsulfatase activity
ETAA1_29190	COG3119	arylsulfatase activity
ETAA1_29300	COG2801	Transposase and inactivated derivatives
ETAA1_29310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETAA1_29360	COG4804	nuclease activity
ETAA1_29370	COG4804	nuclease activity
ETAA1_29520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETAA1_29610	COG2226	methyltransferase
ETAA1_29830	COG0596	Alpha beta hydrolase
ETAA1_29950	COG3119	arylsulfatase activity
ETAA1_29960	COG3119	arylsulfatase activity
ETAA1_30070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETAA1_30090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA1_30120	COG0322	excinuclease ABC activity
ETAA1_30150	COG1136	(ABC) transporter
ETAA1_30160	COG0577	efflux transmembrane transporter activity
ETAA1_30160	COG1136	(ABC) transporter
ETAA1_30200	COG0604	alcohol dehydrogenase
ETAA1_30200	COG3321	synthase
ETAA1_30210	COG0616	signal peptide processing
ETAA1_30230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ETAA1_30260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_30290	COG2226	methyltransferase
ETAA1_30300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ETAA1_30310	COG3119	arylsulfatase activity
ETAA1_30320	COG0202	RNA polymerase activity
ETAA1_30330	COG0343	queuine tRNA-ribosyltransferase activity
ETAA1_30370	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA1_30410	COG3119	arylsulfatase activity
ETAA1_30420	COG3119	arylsulfatase activity
ETAA1_30450	COG3119	arylsulfatase activity
ETAA1_30500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETAA1_30510	COG0746	molybdenum cofactor guanylyltransferase activity
ETAA1_30520	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ETAA1_30550	COG1131	(ABC) transporter
ETAA1_30580	COG2718	Belongs to the UPF0229 family
ETAA1_30600	COG2719	SpoVR family
ETAA1_30630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETAA1_30640	COG0156	8-amino-7-oxononanoate synthase activity
ETAA1_30650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETAA1_30670	COG2264	protein methyltransferase activity
ETAA1_30710	COG1331	Highly conserved protein containing a thioredoxin domain
ETAA1_30750	COG0552	protein localization to endoplasmic reticulum
ETAA1_30760	COG1418	mRNA catabolic process
ETAA1_30820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA1_30830	COG3494	Protein of unknown function (DUF1009)
ETAA1_30890	COG0701	Predicted permease
ETAA1_30900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA1_30920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETAA1_30930	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
ETAA1_30950	COG0825	malonyl-CoA metabolic process
ETAA1_30960	COG0515	serine threonine protein kinase
ETAA1_30960	COG2815	serine threonine protein kinase
ETAA1_31020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA1_31100	COG0515	serine threonine protein kinase
ETAA1_31100	COG0457	Tetratricopeptide repeat
ETAA1_31160	COG0217	transcriptional regulatory protein
ETAA1_31180	COG2766	serine protein kinase
ETAA1_31220	COG3663	DNA glycosylase
ETAA1_31250	COG0438	transferase activity, transferring glycosyl groups
ETAA1_31260	COG0673	inositol 2-dehydrogenase activity
ETAA1_31280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA1_31290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETAA1_31300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETAA1_31320	COG1657	PFAM Prenyltransferase squalene oxidase
ETAA1_31340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETAA1_31360	COG0495	leucyl-tRNA aminoacylation
ETAA1_31410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETAA1_31430	COG2204	response regulator
ETAA1_31440	COG4191	Histidine kinase
ETAA1_31470	COG2321	neutral zinc metallopeptidase
ETAA1_31510	COG1215	transferase activity, transferring glycosyl groups
ETAA1_31550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ETAA1_31560	COG3706	GGDEF domain
ETAA1_31580	COG1691	(AIR) carboxylase
ETAA1_31660	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETAA1_31700	COG1404	Belongs to the peptidase S8 family
ETAA1_31730	COG0745	RESPONSE REGULATOR receiver
ETAA1_31780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ETAA1_31800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETAA1_31870	COG0436	Aminotransferase
ETAA1_31880	COG0386	Belongs to the glutathione peroxidase family
ETAA1_31910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETAA1_31930	COG0583	DNA-binding transcription factor activity
ETAA1_31940	COG1921	L-seryl-tRNASec selenium transferase activity
ETAA1_31990	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ETAA1_32000	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA1_32020	COG4555	ABC transporter
ETAA1_32030	COG2204	response regulator
ETAA1_32060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETAA1_32100	COG0628	permease
ETAA1_32110	COG2205	protein histidine kinase activity
ETAA1_32120	COG0784	Response regulator, receiver
ETAA1_32130	COG4251	negative regulation of phosphorylation
ETAA1_32140	COG2204	response regulator
ETAA1_32190	COG1295	ribonuclease BN
ETAA1_32200	COG5487	UPF0391 membrane protein
ETAA1_32290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_32290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_32360	COG1484	DNA-dependent DNA replication
ETAA1_32580	COG2815	serine threonine protein kinase
ETAA1_32580	COG0515	serine threonine protein kinase
ETAA1_32730	COG2815	serine threonine protein kinase
ETAA1_32730	COG0515	serine threonine protein kinase
ETAA1_32760	COG0515	serine threonine protein kinase
ETAA1_32760	COG2815	serine threonine protein kinase
ETAA1_32850	COG0784	Response regulator, receiver
ETAA1_32850	COG2205	protein histidine kinase activity
ETAA1_32850	COG5002	protein histidine kinase activity
ETAA1_32870	COG0745	RESPONSE REGULATOR receiver
ETAA1_33000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETAA1_33200	COG2801	Transposase and inactivated derivatives
ETAA1_33250	COG0577	efflux transmembrane transporter activity
ETAA1_33250	COG1136	(ABC) transporter
ETAA1_33510	COG1607	acyl-coa hydrolase
ETAA1_33560	COG0310	cobalt ion transport
ETAA1_33570	COG1193	negative regulation of DNA recombination
ETAA1_33690	COG1879	ABC-type sugar transport system periplasmic component
ETAA1_33700	COG1129	ABC transporter
ETAA1_33730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA1_33740	COG1321	iron dependent repressor
ETAA1_33800	COG0442	prolyl-tRNA aminoacylation
ETAA1_33830	COG1131	(ABC) transporter
ETAA1_33830	COG0842	Transport permease protein
ETAA1_33830	COG1716	ATPase activity
ETAA1_33840	COG0205	6-phosphofructokinase activity
ETAA1_33850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETAA1_33880	COG0009	L-threonylcarbamoyladenylate synthase
ETAA1_33940	COG0673	inositol 2-dehydrogenase activity
ETAA1_33960	COG4581	dead DEAH box helicase
ETAA1_33970	COG0788	formyltetrahydrofolate deformylase activity
ETAA1_33980	COG0531	amino acid
ETAA1_34010	COG0352	thiamine-phosphate diphosphorylase activity
ETAA1_34040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETAA1_34050	COG0187	DNA topoisomerase II activity
ETAA1_34060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETAA1_34070	COG0126	phosphoglycerate kinase activity
ETAA1_34080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETAA1_34110	COG0736	holo-[acyl-carrier-protein] synthase activity
ETAA1_34130	COG0405	Gamma-glutamyltransferase
ETAA1_34160	COG0023	Translation Initiation Factor
ETAA1_34170	COG3852	Histidine kinase
ETAA1_34180	COG2204	response regulator
ETAA1_34190	COG2319	Wd-40 repeat
ETAA1_34280	COG0656	L-ascorbic acid biosynthetic process
ETAA1_34290	COG1233	COG1233 Phytoene dehydrogenase and related
ETAA1_34320	COG1940	carbohydrate kinase activity
ETAA1_34340	COG0135	phosphoribosylanthranilate isomerase activity
ETAA1_34350	COG1940	carbohydrate kinase activity
ETAA1_34360	COG0483	inositol monophosphate 1-phosphatase activity
ETAA1_34380	COG0515	serine threonine protein kinase
ETAA1_34390	COG0504	CTP synthase activity
ETAA1_34400	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ETAA1_34490	COG1309	transcriptional regulator
ETAA1_34510	COG1136	(ABC) transporter
ETAA1_34540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETAA1_34650	COG2353	YceI-like domain
ETAA1_34690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ETAA1_34700	COG0714	Associated with various cellular activities
ETAA1_34760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA1_34790	COG1595	DNA-templated transcription, initiation
ETAA1_34830	COG4191	Histidine kinase
ETAA1_34890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETAA1_34920	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ETAA1_34930	COG3684	Belongs to the aldolase LacD family
ETAA1_34970	COG4221	oxidoreductase activity
ETAA1_35010	COG0714	Associated with various cellular activities
ETAA1_35080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA1_35160	COG0673	inositol 2-dehydrogenase activity
ETAA1_35190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ETAA1_35220	COG4208	sulfate ABC transporter
ETAA1_35270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_35320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_35340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_35350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETAA1_35380	COG0793	Belongs to the peptidase S41A family
ETAA1_35410	COG0463	Glycosyl transferase, family 2
ETAA1_35440	COG0714	Associated with various cellular activities
ETAA1_35480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETAA1_35520	COG1132	(ABC) transporter
ETAA1_35530	COG0483	inositol monophosphate 1-phosphatase activity
ETAA1_35550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA1_35580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETAA1_35610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA1_35620	COG0525	valine-tRNA ligase activity
ETAA1_35640	COG1597	lipid kinase activity
ETAA1_35650	COG0640	Transcriptional regulator
ETAA1_35680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA1_35690	COG4191	Histidine kinase
ETAA1_35710	COG0793	Belongs to the peptidase S41A family
ETAA1_35750	COG0463	Glycosyl transferase, family 2
ETAA1_35780	COG0134	indole-3-glycerol-phosphate synthase activity
ETAA1_35810	COG0124	histidyl-tRNA synthetase
ETAA1_35820	COG0517	IMP dehydrogenase activity
ETAA1_35820	COG1994	Peptidase M50
ETAA1_35840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA1_35860	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETAA1_35920	COG0515	serine threonine protein kinase
ETAA1_35920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA1_36040	COG0613	PHP domain protein
ETAA1_36060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA1_36150	COG0523	cobalamin synthesis protein
ETAA1_36210	COG1007	ATP synthesis coupled electron transport
ETAA1_36250	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ETAA1_36320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETAA1_36330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA1_36360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_36440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_36470	COG5433	transposase activity
ETAA1_36550	COG0673	inositol 2-dehydrogenase activity
ETAA1_36560	COG0505	Belongs to the CarA family
ETAA1_36590	COG0493	'glutamate synthase
ETAA1_36590	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ETAA1_36600	COG0297	glycogen (starch) synthase activity
ETAA1_36770	COG1902	pentaerythritol trinitrate reductase activity
ETAA1_36830	COG2135	peptidase activity
ETAA1_36870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETAA1_36880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_36910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETAA1_37080	COG0515	serine threonine protein kinase
ETAA1_37150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA1_37150	COG0515	serine threonine protein kinase
ETAA1_37270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_37350	COG2226	methyltransferase
ETAA1_37380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA1_37400	COG0577	efflux transmembrane transporter activity
ETAA1_37400	COG1136	(ABC) transporter
ETAA1_37450	COG0346	lactoylglutathione lyase activity
ETAA1_37470	COG0604	alcohol dehydrogenase
ETAA1_37530	COG0657	acetylesterase activity
ETAA1_37530	COG2755	lipolytic protein G-D-S-L family
ETAA1_37540	COG0667	Aldo Keto reductase
ETAA1_37600	COG3059	membrane
ETAA1_37610	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETAA1_37780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ETAA1_38280	COG0515	serine threonine protein kinase
ETAA1_38280	COG2815	serine threonine protein kinase
ETAA1_38290	COG2815	serine threonine protein kinase
ETAA1_38290	COG0515	serine threonine protein kinase
ETAA1_38310	COG2815	serine threonine protein kinase
ETAA1_38310	COG0515	serine threonine protein kinase
ETAA1_38320	COG0515	serine threonine protein kinase
ETAA1_38320	COG2815	serine threonine protein kinase
ETAA1_38330	COG2815	serine threonine protein kinase
ETAA1_38330	COG0515	serine threonine protein kinase
ETAA1_38510	COG5433	transposase activity
ETAA1_38620	COG1793	dna ligase
ETAA1_38630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA1_38740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_38770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_38870	COG0653	protein targeting
ETAA1_38970	COG2267	carboxylic ester hydrolase activity
ETAA1_39000	COG2815	serine threonine protein kinase
ETAA1_39000	COG0515	serine threonine protein kinase
ETAA1_39020	COG3344	reverse transcriptase
ETAA1_39050	COG2815	serine threonine protein kinase
ETAA1_39050	COG0515	serine threonine protein kinase
ETAA1_39090	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_39230	COG0515	serine threonine protein kinase
ETAA1_39230	COG2815	serine threonine protein kinase
ETAA1_39270	COG0515	serine threonine protein kinase
ETAA1_39270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_39280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ETAA1_39300	COG5433	transposase activity
ETAA1_39330	COG2815	serine threonine protein kinase
ETAA1_39330	COG0515	serine threonine protein kinase
ETAA1_39420	COG2433	Pfam Transposase IS66
ETAA1_39430	COG0643	Histidine kinase
ETAA1_39430	COG0784	Response regulator, receiver
ETAA1_39430	COG2198	Histidine kinase
ETAA1_39460	COG0745	RESPONSE REGULATOR receiver
ETAA1_39470	COG2201	protein-glutamate methylesterase activity
ETAA1_39520	COG0589	response to stress
ETAA1_39520	COG0475	glutathione-regulated potassium exporter activity
ETAA1_39530	COG1566	PFAM secretion protein HlyD family protein
ETAA1_39620	COG2326	polyphosphate kinase activity
ETAA1_39670	COG0058	SHG alpha-glucan phosphorylase activity
ETAA1_39690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETAA1_39700	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ETAA1_39720	COG0039	L-malate dehydrogenase activity
ETAA1_39750	COG0386	Belongs to the glutathione peroxidase family
ETAA1_39830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETAA1_39840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETAA1_39870	COG1573	uracil-dna glycosylase
ETAA1_39880	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA1_39900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_39910	COG3385	transposase activity
ETAA1_39940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETAA1_40000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETAA1_40000	COG1648	precorrin-2 dehydrogenase activity
ETAA1_40010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA1_40020	COG2146	nitrite reductase [NAD(P)H] activity
ETAA1_40030	COG0243	molybdopterin cofactor binding
ETAA1_40040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA1_40070	COG2183	response to ionizing radiation
ETAA1_40080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA1_40210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA1_40230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA1_40240	COG1459	type II secretion system
ETAA1_40310	COG1446	asparaginase
ETAA1_40360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA1_40370	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETAA1_40390	COG0515	serine threonine protein kinase
ETAA1_40410	COG1131	(ABC) transporter
ETAA1_40430	COG0765	amino acid transport
ETAA1_40440	COG1126	abc transporter atp-binding protein
ETAA1_40450	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ETAA1_40460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ETAA1_40470	COG1131	(ABC) transporter
ETAA1_40580	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETAA1_40610	COG1918	ferrous iron import across plasma membrane
ETAA1_40610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETAA1_40650	COG1595	DNA-templated transcription, initiation
ETAA1_40670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA1_40680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA1_40710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETAA1_40760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA1_40820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_40820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA1_40900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_40910	COG0457	Tetratricopeptide repeat
ETAA1_40910	COG0515	serine threonine protein kinase
ETAA1_40920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ETAA1_40940	COG0420	3'-5' exonuclease activity
ETAA1_40950	COG0419	ATPase involved in DNA repair
ETAA1_41010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETAA1_41030	COG0436	Aminotransferase
ETAA1_41040	COG2423	ornithine cyclodeaminase activity
ETAA1_41050	COG1546	Belongs to the CinA family
ETAA1_41050	COG1058	Belongs to the CinA family
ETAA1_41100	COG0596	Alpha beta hydrolase
ETAA1_41110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA1_41120	COG3321	synthase
ETAA1_41120	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_41120	COG0604	alcohol dehydrogenase
ETAA1_41130	COG3321	synthase
ETAA1_41130	COG0604	alcohol dehydrogenase
ETAA1_41140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETAA1_41140	COG2070	2-Nitropropane dioxygenase
ETAA1_41150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETAA1_41150	COG0316	Belongs to the HesB IscA family
ETAA1_41190	COG0673	inositol 2-dehydrogenase activity
ETAA1_41200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETAA1_41250	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_41260	COG1834	amidinotransferase
ETAA1_41470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETAA1_41480	COG1333	cytochrome c biogenesis protein
ETAA1_41510	COG0489	protein tyrosine kinase activity
ETAA1_41540	COG3119	arylsulfatase activity
ETAA1_41600	COG0714	Associated with various cellular activities
ETAA1_41640	COG0564	pseudouridine synthase activity
ETAA1_41660	COG0432	Pfam Uncharacterised protein family UPF0047
ETAA1_41750	COG3132	Protein of unknown function, DUF480
ETAA1_41760	COG0542	response to heat
ETAA1_41800	COG1671	Belongs to the UPF0178 family
ETAA1_41840	COG0129	dihydroxy-acid dehydratase activity
ETAA1_41890	COG0714	Associated with various cellular activities
ETAA1_41900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETAA1_41960	COG0750	zinc metalloprotease
ETAA1_41990	COG5564	TIM-barrel signal transduction protein
ETAA1_42060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETAA1_42090	COG1473	amidohydrolase
ETAA1_42100	COG0436	Aminotransferase
ETAA1_42110	COG2815	serine threonine protein kinase
ETAA1_42110	COG0515	serine threonine protein kinase
ETAA1_42120	COG4191	Histidine kinase
ETAA1_42160	COG1966	Carbon starvation protein
ETAA1_42170	COG0783	Belongs to the Dps family
ETAA1_42180	COG0596	Alpha beta hydrolase
ETAA1_42210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_42210	COG0706	membrane insertase activity
ETAA1_42230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETAA1_42300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETAA1_42320	COG1722	exodeoxyribonuclease VII activity
ETAA1_42330	COG1570	exodeoxyribonuclease VII activity
ETAA1_42360	COG0686	Belongs to the AlaDH PNT family
ETAA1_42380	COG2211	Major facilitator Superfamily
ETAA1_42410	COG2199	diguanylate cyclase activity
ETAA1_42450	COG0641	radical SAM
ETAA1_42530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETAA1_42540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETAA1_42550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETAA1_42580	COG0824	Thioesterase
ETAA1_42600	COG1136	(ABC) transporter
ETAA1_42640	COG0165	Argininosuccinate lyase
ETAA1_42780	COG0720	synthase
ETAA1_42790	COG1301	dicarboxylic acid transport
ETAA1_42800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA1_42810	COG0540	Belongs to the ATCase OTCase family
ETAA1_42830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA1_42900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETAA1_42900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA1_42950	COG0573	inorganic phosphate transmembrane transporter activity
ETAA1_42960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_42970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_42980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_43010	COG0556	nucleotide-excision repair
ETAA1_43090	COG2815	serine threonine protein kinase
ETAA1_43090	COG0515	serine threonine protein kinase
ETAA1_43120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA1_43130	COG0602	queuosine metabolic process
ETAA1_43190	COG2975	iron-sulfur cluster assembly
ETAA1_43240	COG0254	rRNA binding
ETAA1_43250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA1_43320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETAA1_43350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ETAA1_43370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA1_43380	COG1053	succinate dehydrogenase
ETAA1_43410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_43420	COG0586	Pfam SNARE associated Golgi protein
ETAA1_43430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ETAA1_43440	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ETAA1_43450	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETAA1_43480	COG1136	(ABC) transporter
ETAA1_43480	COG0577	efflux transmembrane transporter activity
ETAA1_43510	COG1136	(ABC) transporter
ETAA1_43520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA1_43540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETAA1_43540	COG0426	domain, Protein
ETAA1_43550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETAA1_43590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ETAA1_43600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ETAA1_43610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ETAA1_43620	COG2205	protein histidine kinase activity
ETAA1_43630	COG0745	RESPONSE REGULATOR receiver
ETAA1_43640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETAA1_43670	COG0793	Belongs to the peptidase S41A family
ETAA1_43690	COG0596	Alpha beta hydrolase
ETAA1_43690	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETAA1_43740	COG0438	transferase activity, transferring glycosyl groups
ETAA1_43780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETAA1_43810	COG2721	sulfolactate sulfo-lyase activity
ETAA1_43840	COG0805	protein transport
ETAA1_43870	COG4260	virion core protein, lumpy skin disease virus
ETAA1_43890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETAA1_43890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETAA1_43910	COG1758	RNA polymerase activity
ETAA1_43920	COG0194	GDP metabolic process
ETAA1_43930	COG1561	YicC-like family, N-terminal region
ETAA1_43950	COG0149	triose-phosphate isomerase activity
ETAA1_43960	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA1_43970	COG0077	Prephenate dehydratase
ETAA1_43970	COG1605	Chorismate mutase
ETAA1_43980	COG0443	Heat shock 70 kDa protein
ETAA1_44010	COG2208	phosphoserine phosphatase activity
ETAA1_44010	COG2770	Histidine kinase
ETAA1_44020	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETAA1_44020	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETAA1_44060	COG0482	sulfurtransferase activity
ETAA1_44070	COG0667	Aldo Keto reductase
ETAA1_44130	COG3618	amidohydrolase
ETAA1_44200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_44320	COG1663	tetraacyldisaccharide 4'-kinase activity
ETAA1_44330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ETAA1_44330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETAA1_44340	COG0859	PFAM glycosyl transferase family 9
ETAA1_44370	COG0438	transferase activity, transferring glycosyl groups
ETAA1_44410	COG2957	Belongs to the agmatine deiminase family
ETAA1_44420	COG0745	RESPONSE REGULATOR receiver
ETAA1_44450	COG0326	Molecular chaperone. Has ATPase activity
ETAA1_44460	COG2205	protein histidine kinase activity
ETAA1_44470	COG3119	arylsulfatase activity
ETAA1_44520	COG3118	belongs to the thioredoxin family
ETAA1_44530	COG1595	DNA-templated transcription, initiation
ETAA1_44540	COG0673	inositol 2-dehydrogenase activity
ETAA1_44570	COG0183	Belongs to the thiolase family
ETAA1_44630	COG2304	oxidoreductase activity
ETAA1_44640	COG2211	Major facilitator Superfamily
ETAA1_44670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA1_44680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA1_44700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETAA1_44710	COG1482	cell wall glycoprotein biosynthetic process
ETAA1_44720	COG2226	methyltransferase
ETAA1_44780	COG0515	serine threonine protein kinase
ETAA1_44790	COG2095	MarC family integral membrane protein
ETAA1_44830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETAA1_44840	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_44860	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_44940	COG1063	alcohol dehydrogenase
ETAA1_44960	COG2755	lipolytic protein G-D-S-L family
ETAA1_44960	COG0657	acetylesterase activity
ETAA1_44990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA1_45050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_45060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_45090	COG3118	belongs to the thioredoxin family
ETAA1_45100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA1_45110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETAA1_45110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETAA1_45120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETAA1_45130	COG0242	peptide deformylase activity
ETAA1_45150	COG5487	UPF0391 membrane protein
ETAA1_45190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETAA1_45230	COG0714	Associated with various cellular activities
ETAA1_45250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_45270	COG0531	amino acid
ETAA1_45410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA1_45450	COG1408	metallophosphoesterase
ETAA1_45510	COG2304	oxidoreductase activity
ETAA1_45540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETAA1_45570	COG2706	6-phosphogluconolactonase activity
ETAA1_45580	COG0277	FAD linked oxidase domain protein
ETAA1_45590	COG0302	gtp cyclohydrolase
ETAA1_45610	COG3119	arylsulfatase activity
ETAA1_45640	COG1404	Belongs to the peptidase S8 family
ETAA1_45770	COG0527	aspartate kinase activity
ETAA1_45780	COG0156	8-amino-7-oxononanoate synthase activity
ETAA1_45800	COG1191	sigma factor activity
ETAA1_45840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETAA1_45850	COG4974	Belongs to the 'phage' integrase family
ETAA1_45860	COG1609	Transcriptional regulator
ETAA1_45890	COG1160	GTP binding
ETAA1_45910	COG2267	carboxylic ester hydrolase activity
ETAA1_45920	COG3963	phosphatidate phosphatase activity
ETAA1_45990	COG0450	alkyl hydroperoxide reductase
ETAA1_46020	COG1136	(ABC) transporter
ETAA1_46050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETAA1_46060	COG0300	oxidoreductase activity
ETAA1_46150	COG0537	adenosine 5'-monophosphoramidase activity
ETAA1_46160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETAA1_46170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETAA1_46220	COG0564	pseudouridine synthase activity
ETAA1_46270	COG0546	phosphoglycolate phosphatase activity
ETAA1_46280	COG0783	Belongs to the Dps family
ETAA1_46340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA1_46350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA1_46380	COG0714	Associated with various cellular activities
ETAA1_46440	COG0247	lactate metabolic process
ETAA1_46440	COG0277	FAD linked oxidase domain protein
ETAA1_46460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ETAA1_46520	COG0028	Belongs to the TPP enzyme family
ETAA1_46630	COG2226	methyltransferase
ETAA1_46650	COG0116	Belongs to the methyltransferase superfamily
ETAA1_46670	COG1253	flavin adenine dinucleotide binding
ETAA1_46680	COG0659	secondary active sulfate transmembrane transporter activity
ETAA1_46690	COG4651	solute:proton antiporter activity
ETAA1_46690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETAA1_46730	COG0835	chemotaxis
ETAA1_46760	COG0643	Histidine kinase
ETAA1_46760	COG0784	Response regulator, receiver
ETAA1_46760	COG2198	Histidine kinase
ETAA1_46790	COG0864	Transcriptional regulator
ETAA1_46830	COG3119	arylsulfatase activity
ETAA1_46860	COG0366	Alpha amylase catalytic
ETAA1_46890	COG0196	riboflavin kinase activity
ETAA1_47150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA1_47180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA1_47200	COG4712	double-strand break repair protein
ETAA1_47210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA1_47230	COG2815	serine threonine protein kinase
ETAA1_47230	COG0515	serine threonine protein kinase
ETAA1_47240	COG0445	tRNA wobble uridine modification
ETAA1_47250	COG0745	RESPONSE REGULATOR receiver
ETAA1_47300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETAA1_47340	COG0275	rRNA processing
ETAA1_47510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA1_47530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETAA1_47550	COG0459	protein refolding
ETAA1_47560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA1_47620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETAA1_47630	COG0523	cobalamin synthesis protein
ETAA1_47660	COG1253	flavin adenine dinucleotide binding
ETAA1_47720	COG0671	phosphoesterase, PA-phosphatase related
ETAA1_47780	COG0195	Participates in both transcription termination and antitermination
ETAA1_47810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETAA1_47830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETAA1_47870	COG1872	DUF167
ETAA1_47920	COG0649	NAD binding
ETAA1_47940	COG0066	3-isopropylmalate dehydratase activity
ETAA1_47960	COG1131	(ABC) transporter
ETAA1_47980	COG3265	gluconokinase activity
ETAA1_48070	COG0515	serine threonine protein kinase
ETAA1_48070	COG2815	serine threonine protein kinase
ETAA1_48090	COG0848	biopolymer transport protein
ETAA1_48190	COG1073	alpha beta
ETAA1_48210	COG2814	Major facilitator Superfamily
ETAA1_48220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETAA1_48230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETAA1_48230	COG0519	Catalyzes the synthesis of GMP from XMP
ETAA1_48310	COG3119	arylsulfatase activity
ETAA1_48380	COG0515	serine threonine protein kinase
ETAA1_48380	COG2815	serine threonine protein kinase
ETAA1_48410	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ETAA1_48450	COG1229	Formylmethanofuran dehydrogenase subunit A
ETAA1_48460	COG2218	PFAM glutamate synthase alpha subunit domain protein
ETAA1_48510	COG2020	methyltransferase activity
ETAA1_48540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA1_48540	COG0515	serine threonine protein kinase
ETAA1_48580	COG0714	Associated with various cellular activities
ETAA1_48620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_48630	COG1960	acyl-CoA dehydrogenase activity
ETAA1_48690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETAA1_48720	COG0321	lipoyl(octanoyl) transferase activity
ETAA1_48730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETAA1_48750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETAA1_48760	COG0778	Nitroreductase
ETAA1_48770	COG1064	alcohol dehydrogenase
ETAA1_48800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA1_48810	COG0673	inositol 2-dehydrogenase activity
ETAA1_48900	COG3279	Response regulator of the LytR AlgR family
ETAA1_48910	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_48950	COG4969	Belongs to the N-Me-Phe pilin family
ETAA1_48990	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA1_49010	COG1013	pyruvate-flavodoxin oxidoreductase activity
ETAA1_49020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ETAA1_49020	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA1_49030	COG2706	6-phosphogluconolactonase activity
ETAA1_49050	COG1595	DNA-templated transcription, initiation
ETAA1_49060	COG1595	DNA-templated transcription, initiation
ETAA1_49080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETAA1_49090	COG0154	amidase activity
ETAA1_49120	COG4336	lyase activity
ETAA1_49130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA1_49140	COG2081	HI0933 family
ETAA1_49160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETAA1_49310	COG0713	ATP synthesis coupled electron transport
ETAA1_49410	COG0463	Glycosyl transferase, family 2
ETAA1_49440	COG0314	molybdopterin synthase activity
ETAA1_49450	COG0406	alpha-ribazole phosphatase activity
ETAA1_49460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETAA1_49470	COG1215	transferase activity, transferring glycosyl groups
ETAA1_49520	COG0307	riboflavin synthase, alpha
ETAA1_49530	COG0018	arginyl-trna synthetase
ETAA1_49540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA1_49550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETAA1_49570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA1_49620	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA1_49630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_49640	COG1131	(ABC) transporter
ETAA1_49660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA1_49760	COG2815	serine threonine protein kinase
ETAA1_49760	COG0515	serine threonine protein kinase
ETAA1_49780	COG2115	Belongs to the xylose isomerase family
ETAA1_49790	COG0693	protein deglycase activity
ETAA1_49800	COG0567	Dehydrogenase, E1 component
ETAA1_49810	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETAA1_49910	COG2815	serine threonine protein kinase
ETAA1_49910	COG0515	serine threonine protein kinase
ETAA1_49940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA1_50000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA1_50020	COG0405	Gamma-glutamyltransferase
ETAA1_50030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETAA1_50080	COG0824	Thioesterase
ETAA1_50090	COG0681	Belongs to the peptidase S26 family
ETAA1_50100	COG0681	Belongs to the peptidase S26 family
ETAA1_50110	COG0481	GTPase activity
ETAA1_50200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETAA1_50250	COG2815	serine threonine protein kinase
ETAA1_50250	COG0515	serine threonine protein kinase
ETAA1_50280	COG0563	adenylate kinase activity
ETAA1_50290	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_50340	COG1131	(ABC) transporter
ETAA1_50370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETAA1_50370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETAA1_50380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETAA1_50450	COG0463	Glycosyl transferase, family 2
ETAA1_50710	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETAA1_50720	COG0071	Belongs to the small heat shock protein (HSP20) family
ETAA1_50740	COG0515	serine threonine protein kinase
ETAA1_50740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA1_50810	COG0673	inositol 2-dehydrogenase activity
ETAA1_50860	COG1247	-acetyltransferase
ETAA1_50880	COG0745	RESPONSE REGULATOR receiver
ETAA1_50900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETAA1_50970	COG1459	type II secretion system
ETAA1_51030	COG0408	coproporphyrinogen oxidase activity
ETAA1_51090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETAA1_51140	COG0440	acetolactate synthase activity
ETAA1_51170	COG0515	serine threonine protein kinase
ETAA1_51190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ETAA1_51200	COG1595	DNA-templated transcription, initiation
ETAA1_51210	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA1_51220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETAA1_51240	COG0557	exoribonuclease II activity
ETAA1_51290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETAA1_51360	COG0842	Transport permease protein
ETAA1_51360	COG1129	ABC transporter
ETAA1_51400	COG2022	thiamine diphosphate biosynthetic process
ETAA1_51410	COG0515	serine threonine protein kinase
ETAA1_51410	COG2815	serine threonine protein kinase
ETAA1_51450	COG3938	Belongs to the proline racemase family
ETAA1_51470	COG0784	Response regulator, receiver
ETAA1_51470	COG5002	protein histidine kinase activity
ETAA1_51480	COG0745	RESPONSE REGULATOR receiver
ETAA1_51510	COG0673	inositol 2-dehydrogenase activity
ETAA1_51520	COG2890	protein-(glutamine-N5) methyltransferase activity
ETAA1_51570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETAA1_51630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETAA1_51760	COG0159	tryptophan synthase activity
ETAA1_51820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA1_51860	COG1131	(ABC) transporter
ETAA1_51880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA1_51900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA1_51910	COG1643	Atp-dependent helicase
ETAA1_52020	COG1012	belongs to the aldehyde dehydrogenase family
ETAA1_52060	COG0133	tryptophan synthase activity
ETAA1_52080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETAA1_52090	COG2205	protein histidine kinase activity
ETAA1_52090	COG5002	protein histidine kinase activity
ETAA1_52090	COG0784	Response regulator, receiver
ETAA1_52100	COG2154	pterin-4-alpha-carbinolamine dehydratase
ETAA1_52110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETAA1_52170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETAA1_52220	COG0488	(ABC) transporter
ETAA1_52240	COG5487	UPF0391 membrane protein
ETAA1_52270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETAA1_52280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA1_52290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETAA1_52300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA1_52310	COG0154	amidase activity
ETAA1_52350	COG0702	epimerase
ETAA1_52360	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ETAA1_52370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETAA1_52400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETAA1_52410	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ETAA1_52410	COG0662	Cupin 2, conserved barrel domain protein
ETAA1_52430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETAA1_52430	COG0321	lipoyl(octanoyl) transferase activity
ETAA1_52540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA1_52640	COG0673	inositol 2-dehydrogenase activity
ETAA1_52650	COG0142	geranyltranstransferase activity
ETAA1_52680	COG1272	protein, Hemolysin III
ETAA1_52730	COG1215	transferase activity, transferring glycosyl groups
ETAA1_52780	COG4249	Peptidase C14 caspase catalytic subunit p20
ETAA1_52780	COG2319	Wd-40 repeat
ETAA1_52840	COG1045	serine acetyltransferase
ETAA1_52890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETAA1_53160	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ETAA1_53250	COG0109	protoheme IX farnesyltransferase activity
ETAA1_53290	COG1845	cytochrome c oxidase, subunit III
ETAA1_53300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETAA1_53310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETAA1_53380	COG0437	4 iron, 4 sulfur cluster binding
ETAA1_53410	COG4251	negative regulation of phosphorylation
ETAA1_53430	COG5487	UPF0391 membrane protein
ETAA1_53510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETAA1_53520	COG0545	Peptidyl-prolyl cis-trans isomerase
ETAA1_53530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETAA1_53550	COG0515	serine threonine protein kinase
ETAA1_53580	COG0667	Aldo Keto reductase
ETAA1_53630	COG0542	response to heat
ETAA1_53650	COG1082	Xylose isomerase domain protein TIM barrel
ETAA1_53850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETAA1_53860	COG0215	cysteine-tRNA ligase activity
ETAA1_53870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ETAA1_53880	COG0632	four-way junction helicase activity
ETAA1_53920	COG2255	four-way junction helicase activity
ETAA1_53960	COG0577	efflux transmembrane transporter activity
ETAA1_53960	COG0577	efflux transmembrane transporter activity
ETAA1_53970	COG0539	negative regulation of cytoplasmic translation
ETAA1_53980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA1_54000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETAA1_54010	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETAA1_54110	COG1595	DNA-templated transcription, initiation
ETAA1_54170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA1_54200	COG4302	ethanolamine ammonia-lyase activity
ETAA1_54290	COG4122	O-methyltransferase activity
ETAA1_54350	COG0105	UTP biosynthetic process
ETAA1_54470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETAA1_54480	COG0443	Heat shock 70 kDa protein
ETAA1_54490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETAA1_54520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA1_54580	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA1_54650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA1_54660	COG0509	glycine decarboxylation via glycine cleavage system
ETAA1_54700	COG0193	aminoacyl-tRNA hydrolase activity
ETAA1_54710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETAA1_54760	COG4941	Belongs to the sigma-70 factor family
ETAA1_54770	COG3386	PFAM SMP-30 Gluconolaconase
ETAA1_54800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA1_54810	COG3118	belongs to the thioredoxin family
ETAA1_54890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ETAA1_54920	COG0657	acetylesterase activity
ETAA1_54990	COG2271	Major facilitator Superfamily
ETAA1_55000	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA1_55130	COG0515	serine threonine protein kinase
ETAA1_55130	COG2815	serine threonine protein kinase
ETAA1_55140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETAA1_55150	COG0667	Aldo Keto reductase
ETAA1_55160	COG0657	acetylesterase activity
ETAA1_55160	COG2755	lipolytic protein G-D-S-L family
ETAA1_55190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETAA1_55250	COG3104	oligopeptide transport
ETAA1_55260	COG0793	Belongs to the peptidase S41A family
ETAA1_55260	COG4946	Tricorn protease homolog
ETAA1_55600	COG3119	arylsulfatase activity
ETAA1_55630	COG1073	alpha beta
ETAA1_55910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETAA1_55970	COG0515	serine threonine protein kinase
ETAA1_56000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_56020	COG0515	serine threonine protein kinase
ETAA1_56020	COG2815	serine threonine protein kinase
ETAA1_56040	COG2815	serine threonine protein kinase
ETAA1_56040	COG0515	serine threonine protein kinase
ETAA1_56180	COG3119	arylsulfatase activity
ETAA1_56190	COG3119	arylsulfatase activity
ETAA1_56200	COG0457	Tetratricopeptide repeat
ETAA1_56200	COG0515	serine threonine protein kinase
ETAA1_56280	COG4585	Histidine kinase
ETAA1_56290	COG2197	response regulator
ETAA1_56300	COG1187	pseudouridine synthase activity
ETAA1_56310	COG0543	2 iron, 2 sulfur cluster binding
ETAA1_56340	COG2894	cell division
ETAA1_56360	COG1450	Type ii and iii secretion system protein
ETAA1_56390	COG3119	arylsulfatase activity
ETAA1_56410	COG1309	transcriptional regulator
ETAA1_56440	COG1695	Transcriptional regulator
ETAA1_56470	COG0438	transferase activity, transferring glycosyl groups
ETAA1_56480	COG0631	protein serine/threonine phosphatase activity
ETAA1_56500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ETAA1_56510	COG0802	atpase or kinase
ETAA1_56520	COG0529	Catalyzes the synthesis of activated sulfate
ETAA1_56590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETAA1_56590	COG2169	Transcriptional regulator
ETAA1_56610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA1_56670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETAA1_56720	COG2706	6-phosphogluconolactonase activity
ETAA1_56740	COG0515	serine threonine protein kinase
ETAA1_56740	COG2815	serine threonine protein kinase
ETAA1_56760	COG2226	methyltransferase
ETAA1_56780	COG1595	DNA-templated transcription, initiation
ETAA1_56840	COG3852	Histidine kinase
ETAA1_56900	COG0596	Alpha beta hydrolase
ETAA1_56980	COG2382	esterase
ETAA1_56980	COG3693	PFAM glycoside hydrolase, family 10
ETAA1_56980	COG3507	Belongs to the glycosyl hydrolase 43 family
ETAA1_56990	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETAA1_57020	COG1132	(ABC) transporter
ETAA1_57040	COG5609	conserved protein (DUF2294)
ETAA1_57230	COG1506	peptidase
ETAA1_57230	COG0823	Involved in the tonB-independent uptake of proteins
ETAA1_57290	COG4106	trans-aconitate 2-methyltransferase activity
ETAA1_57310	COG1063	alcohol dehydrogenase
ETAA1_57330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA1_57430	COG0515	serine threonine protein kinase
ETAA1_57430	COG2815	serine threonine protein kinase
ETAA1_57550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETAA1_57650	COG1475	DNA binding
ETAA1_57930	COG0513	Belongs to the DEAD box helicase family
ETAA1_57980	COG1136	(ABC) transporter
ETAA1_57990	COG1090	epimerase
ETAA1_58000	COG0542	response to heat
ETAA1_58010	COG0542	response to heat
ETAA1_58030	COG0697	spore germination
ETAA1_58080	COG0516	GMP reductase activity
ETAA1_58080	COG0517	IMP dehydrogenase activity
ETAA1_58130	COG0175	sulfate reduction
ETAA1_58140	COG1959	2 iron, 2 sulfur cluster binding
ETAA1_58150	COG0175	sulfate reduction
ETAA1_58160	COG0529	Catalyzes the synthesis of activated sulfate
ETAA1_58160	COG2895	sulfate adenylyltransferase (ATP) activity
ETAA1_58170	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETAA1_58200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETAA1_58210	COG1131	(ABC) transporter
ETAA1_58310	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_58330	COG1598	PFAM Uncharacterised protein family UPF0150
ETAA1_58340	COG0367	asparagine synthase
ETAA1_58360	COG1136	(ABC) transporter
ETAA1_58360	COG0577	efflux transmembrane transporter activity
ETAA1_58380	COG1562	ergosterol biosynthetic process
ETAA1_58390	COG4106	trans-aconitate 2-methyltransferase activity
ETAA1_58430	COG3119	arylsulfatase activity
ETAA1_58460	COG0612	Peptidase, M16
ETAA1_58520	COG2217	Heavy metal translocating P-type atpase
ETAA1_58560	COG2813	Specifically methylates the guanine in position
ETAA1_58580	COG2815	serine threonine protein kinase
ETAA1_58580	COG0515	serine threonine protein kinase
ETAA1_58630	COG1136	(ABC) transporter
ETAA1_58630	COG0577	efflux transmembrane transporter activity
ETAA1_58700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA1_58720	COG2205	protein histidine kinase activity
ETAA1_58760	COG4249	Peptidase C14 caspase catalytic subunit p20
ETAA1_58760	COG2319	Wd-40 repeat
ETAA1_58810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA1_58820	COG2815	serine threonine protein kinase
ETAA1_58820	COG0515	serine threonine protein kinase
ETAA1_58830	COG2815	serine threonine protein kinase
ETAA1_58830	COG0515	serine threonine protein kinase
ETAA1_58950	COG0631	protein serine/threonine phosphatase activity
ETAA1_59030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETAA1_59070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETAA1_59120	COG0673	inositol 2-dehydrogenase activity
ETAA1_59170	COG3119	arylsulfatase activity
ETAA1_59190	COG3119	arylsulfatase activity
ETAA1_59210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA1_59250	COG5433	transposase activity
ETAA1_59330	COG0438	transferase activity, transferring glycosyl groups
ETAA1_59420	COG0166	Belongs to the GPI family
ETAA1_59440	COG3119	arylsulfatase activity
ETAA1_59480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA1_59600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETAA1_59610	COG3119	arylsulfatase activity
ETAA1_59680	COG1505	serine-type exopeptidase activity
ETAA1_59710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETAA1_59780	COG1192	Involved in chromosome partitioning
ETAA1_59820	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_59930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETAA1_59950	COG0586	Pfam SNARE associated Golgi protein
ETAA1_60040	COG0709	Synthesizes selenophosphate from selenide and ATP
ETAA1_60100	COG0356	it plays a direct role in the translocation of protons across the membrane
ETAA1_60110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA1_60120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ETAA1_60130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA1_60140	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETAA1_60150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETAA1_60170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETAA1_60180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETAA1_60300	COG3119	arylsulfatase activity
ETAA1_60620	COG2318	DinB family
ETAA1_60650	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_60670	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA1_60740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA1_60820	COG0753	catalase activity
ETAA1_60920	COG0457	Tetratricopeptide repeat
ETAA1_60920	COG0515	serine threonine protein kinase
ETAA1_60930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA1_60940	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_60950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA1_60960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA1_60980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA1_61030	COG0275	rRNA processing
ETAA1_61040	COG2217	Heavy metal translocating P-type atpase
ETAA1_61050	COG2815	serine threonine protein kinase
ETAA1_61050	COG0515	serine threonine protein kinase
ETAA1_61120	COG2165	general secretion pathway protein
ETAA1_61190	COG0698	ribose 5-phosphate isomerase
ETAA1_61250	COG1620	l-lactate permease
ETAA1_61380	COG1151	hydroxylamine reductase activity
ETAA1_61470	COG0243	molybdopterin cofactor binding
ETAA1_61560	COG0515	serine threonine protein kinase
ETAA1_61560	COG2815	serine threonine protein kinase
ETAA1_61600	COG3206	protein involved in exopolysaccharide biosynthesis
ETAA1_61600	COG0489	protein tyrosine kinase activity
ETAA1_61640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA1_61640	COG2755	lipolytic protein G-D-S-L family
ETAA1_61650	COG0438	transferase activity, transferring glycosyl groups
ETAA1_61670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA1_61680	COG0438	transferase activity, transferring glycosyl groups
ETAA1_61690	COG0438	transferase activity, transferring glycosyl groups
ETAA1_61770	COG1045	serine acetyltransferase
ETAA1_61780	COG1215	transferase activity, transferring glycosyl groups
ETAA1_61830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETAA1_61880	COG1595	DNA-templated transcription, initiation
ETAA1_61890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETAA1_61920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETAA1_61940	COG0726	polysaccharide deacetylase
ETAA1_61990	COG1476	TRANSCRIPTIONal
ETAA1_62010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA1_62020	COG0367	asparagine synthase
ETAA1_62040	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA1_62060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETAA1_62210	COG1595	DNA-templated transcription, initiation
ETAA1_62220	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA1_62260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA1_62280	COG4279	zinc finger
ETAA1_62290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA1_62320	COG0427	acetyl-CoA hydrolase
ETAA1_62340	COG3259	Nickel-dependent hydrogenase
ETAA1_62390	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA1_62390	COG1013	pyruvate-flavodoxin oxidoreductase activity
ETAA1_62390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ETAA1_62390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA1_62400	COG0167	dihydroorotate dehydrogenase activity
ETAA1_62410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ETAA1_62420	COG0375	protein maturation
ETAA1_62440	COG0298	carbon dioxide binding
ETAA1_62500	COG4935	Belongs to the peptidase S8 family
ETAA1_62500	COG1404	Belongs to the peptidase S8 family
ETAA1_62670	COG1032	radical SAM domain protein
ETAA1_62720	COG0516	GMP reductase activity
ETAA1_62720	COG0517	IMP dehydrogenase activity
ETAA1_62740	COG0714	Associated with various cellular activities
ETAA1_62780	COG0488	(ABC) transporter
ETAA1_62820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETAA1_62840	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETAA1_62860	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA1_62870	COG0166	Belongs to the GPI family
ETAA1_62930	COG3119	arylsulfatase activity
ETAA1_62970	COG4864	UPF0365 protein
ETAA1_62980	COG1030	water channel activity
ETAA1_63000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA1_63040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA1_63190	COG1216	Glycosyl transferase, family 2
ETAA1_63210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ETAA1_63230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETAA1_63240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETAA1_63240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETAA1_63260	COG3250	beta-galactosidase activity
ETAA1_63320	COG1297	OPT oligopeptide transporter protein
ETAA1_63420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETAA1_63460	COG1162	GTPase activity
ETAA1_63550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETAA1_63640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETAA1_63690	COG1104	cysteine desulfurase activity