locus-tag	class	description
LPB138_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
LPB138_00025	ENOG4105HHA	aminodeoxychorismate lyase
LPB138_00030	ENOG4105KNA	-acetyltransferase
LPB138_00035	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
LPB138_00040	ENOG4105C0H	protease
LPB138_00055	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
LPB138_00095	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
LPB138_00125	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LPB138_00150	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
LPB138_00155	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
LPB138_00175	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPB138_00180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
LPB138_00185	ENOG4105C1J	atp-dependent rna helicase
LPB138_00195	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
LPB138_00200	ENOG4105VG0	50S ribosomal protein l34
LPB138_00220	ENOG4105FE1	phytoene synthase
LPB138_00240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
LPB138_00280	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
LPB138_00310	ENOG4105DXN	mazG family
LPB138_00320	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
LPB138_00335	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
LPB138_00340	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
LPB138_00350	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
LPB138_00360	ENOG4105BZ1	(ABC) transporter
LPB138_00370	ENOG4105CKK	Glycosyl transferase, family 2
LPB138_00385	ENOG4105E1F	short-chain dehydrogenase reductase
LPB138_00390	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
LPB138_00400	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
LPB138_00430	ENOG4107MM9	BNR Asp-box repeat-containing protein
LPB138_00445	ENOG4105CJ1	ABC, transporter
LPB138_00455	ENOG4105KA0	thioesterase Superfamily protein
LPB138_00475	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
LPB138_00480	ENOG4105QNR	S1 RNA binding domain protein
LPB138_00500	ENOG4105CIY	formyltetrahydrofolate deformylase
LPB138_00510	ENOG4105CUY	Mechanosensitive ion channel
LPB138_00525	ENOG4105CEV	competence damage-inducible protein
LPB138_00530	ENOG4105KDC	50s ribosomal protein l28
LPB138_00535	ENOG41083ND	50S ribosomal protein L33
LPB138_00545	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LPB138_00575	ENOG4107QN1	sodium solute
LPB138_00610	ENOG41081VB	Hydrolase
LPB138_00660	ENOG4105CAT	Cytidine monophosphate kinase
LPB138_00665	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
LPB138_00670	ENOG4105D7A	ATP-binding protein
LPB138_00700	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
LPB138_00710	ENOG4105C1J	atp-dependent rna helicase
LPB138_00715	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
LPB138_00720	ENOG4105BZU	Histidine kinase
LPB138_00730	ENOG4105C5H	ABC transporter
LPB138_00755	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
LPB138_00805	ENOG4108RMU	ferritin dps family protein
LPB138_00815	ENOG4105VN1	Heat shock protein
LPB138_00855	ENOG4107R3N	Filamentation induced by cAMP protein fic
LPB138_00975	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
LPB138_01005	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
LPB138_01095	ENOG4108V1T	peptidylprolyl cis-trans isomerase
LPB138_01145	ENOG4105X54	addiction module antidote protein
LPB138_01255	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_01265	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
LPB138_01315	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
LPB138_01330	ENOG4105BZ1	(ABC) transporter
LPB138_01335	ENOG4107R6T	Involved in the transcription termination process (By similarity)
LPB138_01345	ENOG4105VIE	preprotein translocase, subunit YajC
LPB138_01355	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
LPB138_01370	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
LPB138_01380	ENOG4105VEQ	Cold shock protein
LPB138_01395	ENOG4107VAM	peptidase, m28
LPB138_01400	ENOG4105E0A	ABC, transporter
LPB138_01405	ENOG4105EHG	Permease protein
LPB138_01410	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
LPB138_01415	ENOG4108XM1	transcriptional regulator AsnC family
LPB138_01420	ENOG4105C28	cystathionine
LPB138_01425	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
LPB138_01440	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
LPB138_01445	ENOG4107U9T	Pfam:Ribonuclease_BN
LPB138_01450	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
LPB138_01460	ENOG4105CUT	histidyl-tRNA synthetase
LPB138_01465	ENOG4105EUJ	GTP cyclohydrolase i
LPB138_01495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
LPB138_01510	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
LPB138_01520	ENOG4108WBT	adenosyltransferase
LPB138_01535	ENOG4105D75	Capsular exopolysaccharide family
LPB138_01545	ENOG4105D3Q	Sugar transferase
LPB138_01550	ENOG4105C9Q	fumarate hydratase class II
LPB138_01555	ENOG4107RNH	Outer membrane receptor FepA
LPB138_01560	ENOG4105K89	arsenate reductase
LPB138_01575	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
LPB138_01585	ENOG4107VAM	peptidase, m28
LPB138_01590	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
LPB138_01610	ENOG4105CK2	sodium dicarboxylate symporter
LPB138_01620	ENOG4105D7Z	glutathione synthase
LPB138_01625	ENOG4105KHC	sulfurtransferase
LPB138_01645	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
LPB138_01650	ENOG4105C19	ABC transporter
LPB138_01655	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
LPB138_01660	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
LPB138_01665	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
LPB138_01670	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
LPB138_01680	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
LPB138_01685	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
LPB138_01705	ENOG4108V06	Glutathione peroxidase
LPB138_01715	ENOG4105FJR	Lmbe family
LPB138_01725	ENOG4105C26	Dehydrogenase
LPB138_01740	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
LPB138_01750	ENOG4105CSM	endonuclease III
LPB138_01755	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_01765	ENOG4107ZT5	Thiol disulfide interchange protein
LPB138_01800	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
LPB138_01805	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_01810	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
LPB138_01820	ENOG4105CCS	Glutamate formiminotransferase
LPB138_01825	ENOG4107QQG	Dehydrogenase
LPB138_01855	ENOG4106WTF	Glycosyl transferase, family 2
LPB138_01875	ENOG4105K64	Glycosyl transferase, family 2
LPB138_01915	ENOG4105D2T	synthase
LPB138_01920	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
LPB138_01930	ENOG4108JQ1	Dehydrogenase
LPB138_01940	ENOG4107T8Q	Glycosyl transferase (Group 1
LPB138_01960	ENOG4107T8Q	Glycosyl transferase (Group 1
LPB138_01990	ENOG4105DNZ	Alpha Beta Hydrolase
LPB138_01995	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
LPB138_02000	ENOG4108IUZ	ABC transporter
LPB138_02010	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
LPB138_02015	ENOG4105C2X	Arabinose 5-phosphate isomerase
LPB138_02020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LPB138_02040	ENOG4105WH1	Two component transcriptional regulator luxr family
LPB138_02045	ENOG4105WH1	Two component transcriptional regulator luxr family
LPB138_02090	ENOG4105C25	Primosomal protein n'
LPB138_02100	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
LPB138_02140	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
LPB138_02145	ENOG4108UJU	UPF0301 protein
LPB138_02150	ENOG4105K70	DNA-binding protein
LPB138_02155	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
LPB138_02160	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LPB138_02175	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
LPB138_02185	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
LPB138_02190	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
LPB138_02210	ENOG4105C7H	Helicase, RecD TraA family
LPB138_02230	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
LPB138_02235	ENOG4105CUG	Oligopeptidase b
LPB138_02250	ENOG4105CSR	polyphosphate kinase 2
LPB138_02255	ENOG4105CSR	polyphosphate kinase 2
LPB138_02300	ENOG4105DY9	regulatoR
LPB138_02310	ENOG4107T94	Endo-14-beta-xylanase
LPB138_02315	ENOG4108HKT	sucrose-6-phosphate hydrolase
LPB138_02320	ENOG4108UAJ	Transcriptional regulator
LPB138_02335	ENOG4105DWT	malate dehydrogenase (quinone)
LPB138_02340	ENOG4105DZR	Type I site-specific deoxyribonuclease
LPB138_02370	ENOG4106UW1	Major Facilitator superfamily
LPB138_02375	ENOG4105K5B	UPF0225 protein
LPB138_02405	ENOG4107J0C	type IIi
LPB138_02415	ENOG4107QMH	DNA methylase
LPB138_02445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_02455	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
LPB138_02480	ENOG4105CHH	sulfate transporter
LPB138_02490	ENOG4105C6E	dna polymerase iii
LPB138_02500	ENOG4108ETH	Formylglycinamide ribotide synthetase
LPB138_02510	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
LPB138_02520	ENOG4105C5E	polysaccharide biosynthesis protein
LPB138_02530	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
LPB138_02560	ENOG4108MR6	WD40-like Beta Propeller Repeat
LPB138_02575	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
LPB138_02580	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
LPB138_02585	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
LPB138_02590	ENOG4108KPZ	tonB-dependent Receptor
LPB138_02600	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
LPB138_02605	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
LPB138_02615	ENOG4105DCF	alanine dehydrogenase
LPB138_02620	ENOG4105K8N	protein family UPF0079, ATPase
LPB138_02625	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LPB138_02630	ENOG4105DCI	Phosphohydrolase
LPB138_02635	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB138_02640	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB138_02645	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB138_02650	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
LPB138_02655	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB138_02670	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
LPB138_02695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
LPB138_02705	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
LPB138_02715	ENOG4105ENX	hydrolase
LPB138_02730	ENOG41090A1	ferritin
LPB138_02750	ENOG4108NEV	two component transcriptional regulator, LytTR family
LPB138_02765	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
LPB138_02770	ENOG4105EYW	Ion transport protein
LPB138_02785	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
LPB138_02790	ENOG4105DFA	alanine racemase domain protein
LPB138_02800	ENOG4108JQ1	Dehydrogenase
LPB138_02805	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
LPB138_02815	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
LPB138_02820	ENOG4105E9M	CRISPR-associated protein, Csn1 family
LPB138_02830	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
LPB138_02840	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
LPB138_02845	ENOG4105C3G	gtp-binding protein
LPB138_02860	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
LPB138_02865	ENOG4105DF5	DNA topoisomerase IV, subunit A
LPB138_02875	ENOG4105D64	Mechanosensitive ion channel
LPB138_02890	ENOG4107QWR	cellulase (EC 3.2.1.4)
LPB138_02900	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
LPB138_02905	ENOG4105D05	Receptor
LPB138_02920	ENOG4105C4R	Atp-dependent dna helicase
LPB138_02930	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
LPB138_02935	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPB138_02940	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LPB138_02965	ENOG4107QX9	Thiol disulfide interChange protein
LPB138_02970	ENOG4105C8Y	Acetylornithine aminotransferase
LPB138_02980	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
LPB138_02985	ENOG41090R7	Ferric uptake
LPB138_02990	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
LPB138_02995	ENOG4105D0M	Protease HtpX homolog
LPB138_03000	ENOG4107TT5	NLP P60 protein
LPB138_03005	ENOG4108RWN	rrna methyltransferase
LPB138_03015	ENOG4105CD3	dihydroorotase
LPB138_03025	ENOG4105CDU	Replicative dna helicase
LPB138_03035	ENOG4105CV1	Transketolase (EC 2.2.1.1)
LPB138_03040	ENOG4105CPK	Glycosyl transferase (Group 1
LPB138_03045	ENOG4105D49	3-dehydroquinate synthase
LPB138_03070	ENOG4105CI3	gtp-binding protein typa
LPB138_03100	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
LPB138_03115	ENOG4105DT9	hydrolase family 43
LPB138_03120	ENOG4105CT4	transporter
LPB138_03125	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
LPB138_03130	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
LPB138_03140	ENOG4107QNK	)-transporter
LPB138_03165	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LPB138_03170	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LPB138_03175	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
LPB138_03200	ENOG4105ETE	Transcriptional regulator (LacI family
LPB138_03225	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
LPB138_03240	ENOG4105R8C	Transcriptional regulator
LPB138_03255	ENOG4105BZS	acriflavin resistance protein
LPB138_03260	ENOG410624X	efflux transporter, rnd family, mfp subunit
LPB138_03275	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
LPB138_03300	ENOG4105VEQ	Cold shock protein
LPB138_03305	ENOG4105DQ4	alcohol dehydrogenase
LPB138_03310	ENOG4108Z9K	Osmotically inducible protein
LPB138_03320	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
LPB138_03340	ENOG4105NPQ	Pfam:DUF403
LPB138_03360	ENOG4105VEQ	Cold shock protein
LPB138_03390	ENOG4105C1J	atp-dependent rna helicase
LPB138_03410	ENOG4108NEV	two component transcriptional regulator, LytTR family
LPB138_03420	ENOG4105BZU	Histidine kinase
LPB138_03450	ENOG4105KVH	Transcriptional regulator
LPB138_03460	ENOG4105CEP	NADH dehydrogenase
LPB138_03495	ENOG41088SP	formiminoglutamate hydrolase
LPB138_03500	ENOG4105CI2	imidazolone-5-propionate hydrolase
LPB138_03505	ENOG4105CGP	Urocanate hydratase
LPB138_03510	ENOG4105C84	Histidine ammonia-lyase
LPB138_03525	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
LPB138_03555	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LPB138_03560	ENOG4108R99	pseudouridine synthase
LPB138_03575	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
LPB138_03605	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
LPB138_03620	ENOG4105C1J	atp-dependent rna helicase
LPB138_03650	ENOG4105EN6	Membrane
LPB138_03655	ENOG4105CPP	Dehydrogenase, E1 component
LPB138_03660	ENOG4108VVK	transcriptional Regulator, AsnC
LPB138_03675	ENOG4105CD8	aminopeptidase N
LPB138_03695	ENOG4105GFR	rna polymerase sigma factor
LPB138_03715	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
LPB138_03720	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
LPB138_03725	ENOG4105CFH	Aspartokinase
LPB138_03730	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
LPB138_03735	ENOG4105D98	threonine synthase
LPB138_03740	ENOG4105C6K	Malic enzyme
LPB138_03745	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
LPB138_03755	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
LPB138_03760	ENOG4107RAQ	aminopeptidase
LPB138_03765	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
LPB138_03780	ENOG4105CGY	Dna recombination protein
LPB138_03785	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
LPB138_03800	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
LPB138_03820	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
LPB138_03830	ENOG4108Z03	MAF-like protein
LPB138_03835	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
LPB138_03850	ENOG4105VEJ	Heat shock protein
LPB138_03855	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
LPB138_03860	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
LPB138_03905	ENOG4105CHR	reductase
LPB138_03910	ENOG4105BZU	Histidine kinase
LPB138_03925	ENOG4105C19	ABC transporter
LPB138_03935	ENOG4107RBB	ABC transporter, permease
LPB138_03940	ENOG4105C19	ABC transporter
LPB138_03985	ENOG4107QKV	phosphomannomutase
LPB138_03990	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
LPB138_03995	ENOG4105DY9	regulatoR
LPB138_04010	ENOG4108HRK	Histidine kinase
LPB138_04040	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
LPB138_04050	ENOG4108YYS	metal-dependent hydrolase (By similarity)
LPB138_04055	ENOG4108Z7F	N-acetyltransferase
LPB138_04075	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
LPB138_04080	ENOG4108Z7R	Chaperone CsaA
LPB138_04090	ENOG4105CQB	FAD linked oxidase domain protein
LPB138_04100	ENOG4107R7I	amino acid
LPB138_04130	ENOG4108RMU	ferritin dps family protein
LPB138_04135	ENOG4105C5Q	Transcriptional regulator
LPB138_04160	ENOG4105DG6	mannose-6-phosphate isomerase
LPB138_04165	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_04175	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
LPB138_04190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
LPB138_04210	ENOG4105VEQ	Cold shock protein
LPB138_04215	ENOG4105VEQ	Cold shock protein
LPB138_04220	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
LPB138_04225	ENOG4105C98	muts2 protein
LPB138_04230	ENOG4105ER2	Ompa motb domain protein
LPB138_04235	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
LPB138_04245	ENOG4107QI1	Mate efflux family protein
LPB138_04250	ENOG4105D3R	alkyl hydroperoxide reductase
LPB138_04255	ENOG41080RH	Thioredoxin
LPB138_04270	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
LPB138_04275	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
LPB138_04285	ENOG4105CNU	cell division protein FtsK
LPB138_04300	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
LPB138_04310	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
LPB138_04325	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
LPB138_04330	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
LPB138_04340	ENOG4105C8N	cysteinyl-tRNA synthetase
LPB138_04350	ENOG4105CKK	Glycosyl transferase, family 2
LPB138_04380	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
LPB138_04385	ENOG4108V1T	peptidylprolyl cis-trans isomerase
LPB138_04395	ENOG4105SFS	phosphoesterase RecJ domain protein
LPB138_04400	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
LPB138_04420	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
LPB138_04430	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
LPB138_04440	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
LPB138_04445	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
LPB138_04470	ENOG4105DEF	Extracellular solute-binding protein, family 5
LPB138_04480	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
LPB138_04490	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
LPB138_04505	ENOG4105E9H	Lytic Murein transglycosylase
LPB138_04520	ENOG4105EA8	2-Nitropropane dioxygenase
LPB138_04525	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
LPB138_04530	ENOG4105E2D	ec 3.2.1.52
LPB138_04570	ENOG4107QTF	adenylosuccinate lyase
LPB138_04580	ENOG4105EE5	Membrane protein terC
LPB138_04590	ENOG4105D05	Receptor
LPB138_04595	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
LPB138_04600	ENOG4105D5U	fad dependent oxidoreductase
LPB138_04605	ENOG4105DEU	major facilitator superfamily
LPB138_04615	ENOG4105E0X	reductase
LPB138_04625	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
LPB138_04630	ENOG4105C8Y	Acetylornithine aminotransferase
LPB138_04645	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
LPB138_04675	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
LPB138_04685	ENOG4107YZX	Universal stress protein
LPB138_04690	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
LPB138_04705	ENOG4105CHM	Aminotransferase
LPB138_04710	ENOG4107R0I	Cell wall formation (By similarity)
LPB138_04725	ENOG4107S6X	Glycosyl transferase, family 2
LPB138_04735	ENOG4105K3M	)-transporter
LPB138_04740	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
LPB138_04750	ENOG4105EHZ	conserved protein UCP016719
LPB138_04775	ENOG4105C75	arginyL-tRNA synthetase
LPB138_04785	ENOG4107QN2	dihydrolipoyl dehydrogenase
LPB138_04790	ENOG41074B2	UPF0747 protein
LPB138_04800	ENOG4105CA0	peroxidase
LPB138_04815	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
LPB138_04825	ENOG4105FE9	pseudouridine synthase
LPB138_04830	ENOG410667J	hydrolase
LPB138_04835	ENOG4105DZ0	fad dependent oxidoreductase
LPB138_04845	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LPB138_04850	ENOG4107QWK	SAICAR synthetase
LPB138_04855	ENOG4105C9A	Phoh family
LPB138_04900	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
LPB138_04910	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
LPB138_04915	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
LPB138_04920	ENOG4105DR9	pseudouridine synthase
LPB138_04975	ENOG4105CTJ	Metal Dependent Phosphohydrolase
LPB138_04980	ENOG4105CHU	acetyl-coa acetyltransferase
LPB138_04985	ENOG4107SN7	NLP P60 protein
LPB138_05020	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_05025	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_05030	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
LPB138_05035	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
LPB138_05050	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
LPB138_05075	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LPB138_05085	ENOG4105CYP	glycoside hydrolase, family
LPB138_05110	ENOG4105D3Q	Sugar transferase
LPB138_05130	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
LPB138_05145	ENOG4107S6X	Glycosyl transferase, family 2
LPB138_05150	ENOG4108KMV	Glycosyl transferase (Group 1
LPB138_05175	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
LPB138_05180	ENOG4107TPS	domain protein
LPB138_05185	ENOG4107TPS	domain protein
LPB138_05190	ENOG4108VCT	Sulfite exporter TauE/SafE
LPB138_05260	ENOG41075H3	AraC family transcriptional regulator
LPB138_05265	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
LPB138_05270	ENOG4105C4M	(Ubiquinol oxidase) subunit I
LPB138_05290	ENOG4105CNT	hydrolase family 2
LPB138_05295	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
LPB138_05310	ENOG4105C27	TonB-dependent Receptor Plug
LPB138_05325	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
LPB138_05330	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
LPB138_05340	ENOG4105CYP	glycoside hydrolase, family
LPB138_05365	ENOG4105ECR	NmrA family
LPB138_05375	ENOG4105KVH	Transcriptional regulator
LPB138_05450	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
LPB138_05460	ENOG4105C59	p-type ATPase
LPB138_05475	ENOG4108IJF	Heavy metal efflux pump, CzcA
LPB138_05520	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_05530	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
LPB138_05535	ENOG4108JYZ	YitT family
LPB138_05595	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
LPB138_05615	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB138_05620	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB138_05625	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
LPB138_05630	ENOG4107VNI	ribosomal protein l10
LPB138_05635	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
LPB138_05640	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
LPB138_05660	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
LPB138_05695	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_05700	ENOG41083X6	30S ribosomal protein S21
LPB138_05705	ENOG4105C1G	acyl-Coa dehydrogenase
LPB138_05715	ENOG4105BZG	amino acid carrier protein
LPB138_05720	ENOG4107SVH	Potassium channel protein
LPB138_05735	ENOG4108URH	decarboxylase
LPB138_05750	ENOG4105CPP	Dehydrogenase, E1 component
LPB138_05765	ENOG4108RCM	Nitroreductase
LPB138_05770	ENOG4105CIN	aminoacyl-histidine dipeptidase
LPB138_05775	ENOG4105ECP	epimerase
LPB138_05780	ENOG4107QJE	Chromosome Partitioning Protein
LPB138_05785	ENOG4105FA0	parb-like partition protein
LPB138_05795	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
LPB138_05800	ENOG4105C3F	Signal peptidase i
LPB138_05825	ENOG4105C5H	ABC transporter
LPB138_05830	ENOG4105C2I	pirin domain protein
LPB138_05835	ENOG41067TZ	transcriptional regulator, MarR family
LPB138_05840	ENOG4105Q8W	reductase
LPB138_05845	ENOG4107QX3	carboxylase
LPB138_05860	ENOG4105CDY	transcriptional regulatory protein
LPB138_05870	ENOG4105CP2	von willebrand factor, type a
LPB138_05890	ENOG4107FCW	Abortive infection protein
LPB138_05895	ENOG4105DTQ	mandelate racemase muconate lactonizing
LPB138_05915	ENOG4107W2A	UPF0173 metal-dependent hydrolase
LPB138_05930	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
LPB138_05940	ENOG4105DF6	Fe-S oxidoreductase
LPB138_05950	ENOG4105DF6	Fe-S oxidoreductase
LPB138_05955	ENOG4107KIA	Virulence factor Mce family protein
LPB138_05960	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
LPB138_05975	ENOG4105CK7	Sodium proline symporter
LPB138_05985	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
LPB138_06000	ENOG4105EMN	RNA polymerase sigma factor
LPB138_06005	ENOG4105C7S	Dehydrogenase
LPB138_06015	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
LPB138_06020	ENOG4108Z9I	-acetyltransferase
LPB138_06025	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
LPB138_06035	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
LPB138_06040	ENOG4105D52	delta-aminolevulinic acid dehydratase
LPB138_06045	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
LPB138_06050	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
LPB138_06060	ENOG4107SF0	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
LPB138_06075	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
LPB138_06085	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
LPB138_06100	ENOG4105UYK	outer membrane protein a
LPB138_06110	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
LPB138_06115	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
LPB138_06120	ENOG4105EGD	dinuclear metal center protein, YbgI family
LPB138_06145	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
LPB138_06155	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPB138_06160	ENOG4107VIJ	nudix hydrolase
LPB138_06205	ENOG41081WG	50s ribosomal protein l31
LPB138_06220	ENOG4105CD3	dihydroorotase
LPB138_06230	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
LPB138_06240	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
LPB138_06250	ENOG4105D05	Receptor
LPB138_06255	ENOG4105D8V	Glucose sorbosone dehydrogenase
LPB138_06265	ENOG4105DHJ	ABC, transporter
LPB138_06270	ENOG4105CY3	ABC transporter, permease
LPB138_06280	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
LPB138_06285	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LPB138_06290	ENOG4105KG3	cytidine deaminase
LPB138_06305	ENOG4105E6M	Sulphatase-modifying factor protein
LPB138_06310	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
LPB138_06325	ENOG4105CTQ	phosphohexokinase
LPB138_06330	ENOG4107T9C	Alpha amylase catalytic region
LPB138_06340	ENOG4108IUK	alpha amylase, catalytic
LPB138_06350	ENOG4107URF	beta-phospho-glucomutase
LPB138_06355	ENOG4105CT4	transporter
LPB138_06360	ENOG4105ETE	Transcriptional regulator (LacI family
LPB138_06365	ENOG4105C27	TonB-dependent Receptor Plug
LPB138_06440	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
LPB138_06450	ENOG4109015	Biopolymer transport protein exbD tolR
LPB138_06460	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
LPB138_06465	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
LPB138_06470	ENOG4105C1G	acyl-Coa dehydrogenase
LPB138_06480	ENOG4108YZA	Nitrogen regulatory protein pii
LPB138_06540	ENOG4105WH1	Two component transcriptional regulator luxr family
LPB138_06555	ENOG4105D7T	ABC transporter
LPB138_06560	ENOG4105DG7	nitrate ABC transporter
LPB138_06575	ENOG4107RNU	major facilitator superfamily MFS_1
LPB138_06580	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
LPB138_06585	ENOG4107QZF	nitrite reductase NADPH large subunit
LPB138_06605	ENOG4105C22	threonyL-tRNA synthetase
LPB138_06610	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
LPB138_06615	ENOG4105VJV	50s ribosomal protein L35
LPB138_06620	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
LPB138_06625	ENOG4107T8T	UPF0173 metal-dependent hydrolase
LPB138_06630	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
LPB138_06635	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
LPB138_06645	ENOG4107R5B	glutamine synthetase
LPB138_06675	ENOG4105CGD	Nad-dependent epimerase dehydratase
LPB138_06700	ENOG4105EUJ	GTP cyclohydrolase i
LPB138_06705	ENOG4105CHR	reductase
LPB138_06710	ENOG4108V06	Glutathione peroxidase
LPB138_06735	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
LPB138_06740	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
LPB138_06745	ENOG4105CP7	Triose-phosphate isomerase
LPB138_06755	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
LPB138_06780	ENOG410904A	RNA polymerase
LPB138_06810	ENOG4108URH	decarboxylase
LPB138_06815	ENOG4105EEI	dihydropteroate synthase
LPB138_06820	ENOG4105C8B	TIGR00159 family
LPB138_06825	ENOG4105BZ1	(ABC) transporter
LPB138_06830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
LPB138_06865	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
LPB138_06880	ENOG4108JU5	Magnesium and cobalt efflux protein
LPB138_06905	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
LPB138_06915	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
LPB138_06935	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
LPB138_06940	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
LPB138_06945	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
LPB138_06955	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
LPB138_06960	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LPB138_06965	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
LPB138_06970	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
LPB138_06980	ENOG4105CDH	Citrulline--aspartate ligase
LPB138_06985	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
LPB138_06990	ENOG4105II7	pyrroline-5-carboxylate reductase
LPB138_06995	ENOG4105C8Y	Acetylornithine aminotransferase
LPB138_07020	ENOG4107T6X	nag kinase
LPB138_07030	ENOG4105CH7	arginosuccinase
LPB138_07035	ENOG4105FE9	pseudouridine synthase
LPB138_07050	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
LPB138_07085	ENOG4105CBX	hi0933 family
LPB138_07100	ENOG4105DUX	Transporter
LPB138_07105	ENOG4105DUX	Transporter
LPB138_07115	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
LPB138_07120	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB138_07130	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
LPB138_07140	ENOG4105CN1	protease
LPB138_07145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LPB138_07190	ENOG4108S2Y	peptide Chain Release factor
LPB138_07195	ENOG4105E0Y	RtcB Protein
LPB138_07240	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
LPB138_07245	ENOG4105NAU	thioesterase Superfamily protein
LPB138_07275	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LPB138_07315	ENOG4105DY9	regulatoR
LPB138_07325	ENOG4105BZU	Histidine kinase
LPB138_07335	ENOG4105BZU	Histidine kinase
LPB138_07350	ENOG4105MSB	protein, conserved in bacteria
LPB138_07370	ENOG4105CSA	Coproporphyrinogen iii oxidase
LPB138_07380	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
LPB138_07390	ENOG4107R8N	Glycosyl transferase, family 2
LPB138_07410	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
LPB138_07425	ENOG4105CM2	brancheD-chain amino acid aminotransferase
LPB138_07445	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LPB138_07455	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
LPB138_07460	ENOG4105M08	Membrane
LPB138_07480	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
LPB138_07485	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
LPB138_07490	ENOG4105K5M	30s ribosomal protein S16
LPB138_07500	ENOG4105C0B	DNA polymerase III (alpha subunit)
LPB138_07520	ENOG4105CJ1	ABC, transporter
LPB138_07555	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
LPB138_07575	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
LPB138_07585	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
LPB138_07595	ENOG4105DFD	Na H antiporter
LPB138_07615	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
LPB138_07620	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
LPB138_07630	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
LPB138_07635	ENOG4105EVN	Prephenate dehydrogenase
LPB138_07640	ENOG4105CHM	Aminotransferase
LPB138_07645	ENOG4105CQC	Prephenate dehydratase
LPB138_07685	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
LPB138_07690	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
LPB138_07700	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
LPB138_07705	ENOG4105D2H	Uronic isomerase
LPB138_07720	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LPB138_07730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB138_07735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB138_07740	ENOG4105ETE	Transcriptional regulator (LacI family
LPB138_07750	ENOG4105CMG	Carbohydrate kinase
LPB138_07755	ENOG4105C93	Xylose Isomerase
LPB138_07765	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
LPB138_07805	ENOG4105DZR	Type I site-specific deoxyribonuclease
LPB138_07815	ENOG4107XZC	Restriction modification system DNA (Specificity
LPB138_07825	ENOG4105CVR	type I restriction-modification system
LPB138_07875	ENOG4105SYT	Methylenetetrahydrofolate reductase
LPB138_07895	ENOG41061CK	Antibiotic biosynthesis monooxygenase
LPB138_07900	ENOG4105C3R	Methionine synthase
LPB138_07905	ENOG4108ZIT	Ferredoxin, 2FE-2S
LPB138_07910	ENOG4105CAY	ferredoxin--nadp reductase
LPB138_07915	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
LPB138_07920	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
LPB138_07925	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
LPB138_07930	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
LPB138_07935	ENOG4105C28	cystathionine
LPB138_07950	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
LPB138_07960	ENOG4105ZMH	deoxynucleoside kinase
LPB138_07970	ENOG4105F0N	pyrophosphate phospho-hydrolase
LPB138_07980	ENOG4105CPP	Dehydrogenase, E1 component
LPB138_07985	ENOG4105BZJ	Electron transfer flavoprotein
LPB138_07990	ENOG4105C10	Electron transfer flavoprotein
LPB138_08000	ENOG4105D9N	nucleoside
LPB138_08005	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
LPB138_08010	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
LPB138_08050	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
LPB138_08055	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
LPB138_08060	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
LPB138_08075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
LPB138_08080	ENOG41086DT	Membrane protein of unknown function
LPB138_08085	ENOG4105EV9	Alpha Beta Hydrolase
LPB138_08090	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
LPB138_08100	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
LPB138_08110	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
LPB138_08115	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPB138_08130	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
LPB138_08135	ENOG4105DY9	regulatoR
LPB138_08140	ENOG4108HRK	Histidine kinase
LPB138_08155	ENOG4105DGW	oligopeptidase A
LPB138_08195	ENOG4105C58	cytochrome c oxidase accessory protein ccog
LPB138_08210	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
LPB138_08230	ENOG4105C59	p-type ATPase
LPB138_08250	ENOG4105CY0	Metallo-Beta-Lactamase
LPB138_08270	ENOG4107YZX	Universal stress protein
LPB138_08290	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LPB138_08310	ENOG4105K63	Thioredoxin
LPB138_08320	ENOG4105DZP	Membrane-associated zinc metalloprotease
LPB138_08360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LPB138_08385	ENOG4105DKQ	ROK family
LPB138_08395	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
LPB138_08530	ENOG4105X54	addiction module antidote protein
LPB138_08605	ENOG4108V5Q	transglutaminase-like protein
LPB138_08610	ENOG4108YYH	Nadph-dependent fmn reductase
LPB138_08635	ENOG4107SET	aldo keto reductase
LPB138_08670	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB138_08705	ENOG4105C0B	DNA polymerase III (alpha subunit)
LPB138_08710	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
LPB138_08715	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
LPB138_08730	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
LPB138_08740	ENOG4105EKX	Restriction modification system DNA (Specificity
LPB138_08785	ENOG4107QHF	type ii secretion system protein e
LPB138_08905	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
LPB138_08915	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
LPB138_08970	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
LPB138_08985	ENOG4105MIR	Phenylalanine 4-monooxygenase
LPB138_09000	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
LPB138_09010	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LPB138_09020	ENOG4105CJ2	(LipO)protein
LPB138_09035	ENOG4105C1J	atp-dependent rna helicase
LPB138_09050	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
LPB138_09055	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
LPB138_09060	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
LPB138_09065	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
LPB138_09070	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
LPB138_09080	ENOG4105NWN	ApaG protein
LPB138_09095	ENOG4105C26	Dehydrogenase
LPB138_09105	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
LPB138_09125	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LPB138_09130	ENOG4105C7Z	Conserved Protein
LPB138_09140	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_09205	ENOG4105BZ1	(ABC) transporter
LPB138_09215	ENOG41072GX	Peptidase M22 Glycoprotease
LPB138_09220	ENOG4105DFG	type I secretion outer membrane protein
LPB138_09230	ENOG4108SJC	Membrane
LPB138_09235	ENOG4108KF3	Electron transport protein SCO1 SenC
LPB138_09255	ENOG4105CCU	oxidase (Subunit III)
LPB138_09260	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
LPB138_09275	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
LPB138_09285	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
LPB138_09295	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
LPB138_09300	ENOG4105D78	K07001 NTE family protein
LPB138_09305	ENOG4105C03	ribonuclease
LPB138_09310	ENOG4105K70	DNA-binding protein
LPB138_09320	ENOG4108UUM	single-stranded DNA-binding protein
LPB138_09325	ENOG4108JU5	Magnesium and cobalt efflux protein
LPB138_09360	ENOG4108594	Permease of the drug metabolite transporter
LPB138_09375	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
LPB138_09380	ENOG4105K46	50S ribosomal protein l27
LPB138_09385	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
LPB138_09390	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
LPB138_09395	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LPB138_09410	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
LPB138_09420	ENOG4105D06	uba thif-type nad fad binding protein
LPB138_09430	ENOG4108ZAF	Molybdopterin
LPB138_09445	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
LPB138_09450	ENOG4105C6K	Malic enzyme
LPB138_09455	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
LPB138_09465	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
LPB138_09485	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
LPB138_09490	ENOG4105J5G	Transferase hexapeptide repeat containing protein
LPB138_09505	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
LPB138_09525	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
LPB138_09530	ENOG4108Y6J	UPF0403 protein
LPB138_09540	ENOG4105E39	Enoyl-CoA hydratase
LPB138_09550	ENOG4105W3H	MtN3 and saliva related transmembrane protein
LPB138_09555	ENOG4105DCF	alanine dehydrogenase
LPB138_09560	ENOG4105W3H	MtN3 and saliva related transmembrane protein
LPB138_09565	ENOG4105C8T	Leucyl-tRNA synthetase
LPB138_09575	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
LPB138_09580	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
LPB138_09585	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
LPB138_09590	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
LPB138_09600	ENOG4107RPQ	ABC transporter
LPB138_09605	ENOG4105DSE	periplasmic solute binding protein
LPB138_09610	ENOG4105DIK	(ABC) transporter
LPB138_09620	ENOG4107RPQ	ABC transporter
LPB138_09625	ENOG4107RBD	ABC, transporter
LPB138_09635	ENOG4105CE1	Ferrous iron transport protein b
LPB138_09645	ENOG4108KF3	Electron transport protein SCO1 SenC
LPB138_09650	ENOG4105DZP	Membrane-associated zinc metalloprotease
LPB138_09655	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
LPB138_09675	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LPB138_09680	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
LPB138_09690	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
LPB138_09700	ENOG4108UB4	uncharacterized protein ygjQ
LPB138_09705	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
LPB138_09710	ENOG4105KT5	UmuD protein
LPB138_09715	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
LPB138_09720	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
LPB138_09750	ENOG4105DTN	riboflavin biosynthesis protein ribF
LPB138_09760	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
LPB138_09775	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
LPB138_09780	ENOG4105CJW	magnesium transporter
LPB138_09785	ENOG4105C2N	RNA methyltransferase TrmH family group 3
LPB138_09800	ENOG4107SH3	glycosyl transferase, family 39
LPB138_09805	ENOG4105CKK	Glycosyl transferase, family 2
LPB138_09815	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
LPB138_09830	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
LPB138_09855	ENOG4105BZU	Histidine kinase
LPB138_09860	ENOG4105BZU	Histidine kinase
LPB138_09865	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
LPB138_09870	ENOG4105C5I	Dehydrogenase
LPB138_09905	ENOG4105KAF	membrAne
LPB138_09910	ENOG41082BM	Transcriptional regulator, arsr family
LPB138_09925	ENOG4108EV3	Bifunctional aspartate kinase II homoserine dehydrogenase II
LPB138_09935	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LPB138_09940	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
LPB138_09945	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
LPB138_09955	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
LPB138_09960	ENOG4105VG1	fes assembly suf system protein
LPB138_09985	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
LPB138_10015	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
LPB138_10030	ENOG4105CPN	adenine deaminase
LPB138_10065	ENOG4105C9M	aspartyl-trna synthetase
LPB138_10075	ENOG4105EYW	Ion transport protein
LPB138_10085	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
LPB138_10095	ENOG4108Z6B	deaminase
LPB138_10100	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
LPB138_10105	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
LPB138_10140	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LPB138_10155	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
LPB138_10165	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
LPB138_10180	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
LPB138_10185	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
LPB138_10195	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
LPB138_10210	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
LPB138_10215	ENOG4105CD3	dihydroorotase
LPB138_10230	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
LPB138_10270	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
LPB138_10280	ENOG4105D8V	Glucose sorbosone dehydrogenase
LPB138_10305	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
LPB138_10310	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
LPB138_10315	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LPB138_10320	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
LPB138_10325	ENOG410842R	atp synthase
LPB138_10330	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
LPB138_10365	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
LPB138_10380	ENOG4105C8F	Beta-lactamase domain protein
LPB138_10390	ENOG4105KRF	dihydroneopterin aldolase
LPB138_10395	ENOG4105CBC	glutamate synthase
LPB138_10400	ENOG4105CX6	glutaminyL-tRNA synthetase
LPB138_10410	ENOG4106678	morphogenetic protein associated with SpoVID
LPB138_10415	ENOG4105CGK	Exodeoxyribonuclease III
LPB138_10420	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
LPB138_10425	ENOG4108JQC	penicillin-binding protein 1A
LPB138_10430	ENOG410647Z	gliding motility-associated lipoprotein GldH
LPB138_10435	ENOG4105MA4	psp1 domain protein
LPB138_10440	ENOG4105C72	UPF0176 protein
LPB138_10445	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
LPB138_10450	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
LPB138_10455	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
LPB138_10465	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
LPB138_10470	ENOG4105CCT	upf0313 protein
LPB138_10485	ENOG4105NGQ	Thioredoxin
LPB138_10490	ENOG4107R6D	beta-lactam binding protein AmpH
LPB138_10515	ENOG4107R37	Glutamate dehydrogenase
LPB138_10520	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
LPB138_10530	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
LPB138_10540	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
LPB138_10545	ENOG4105KBX	Transcriptional regulator, TetR family
LPB138_10555	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
LPB138_10565	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
LPB138_10575	ENOG4108SA1	esterase
LPB138_10580	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
LPB138_10590	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LPB138_10595	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
LPB138_10600	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
LPB138_10630	ENOG4105PGM	cation diffusion facilitator family transporter
LPB138_10635	ENOG4108YZG	isomerase
LPB138_10645	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
LPB138_10655	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
LPB138_10670	ENOG4108S4H	thioesterase Superfamily protein
LPB138_10675	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
LPB138_10695	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
LPB138_10700	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
LPB138_10710	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
LPB138_10725	ENOG4107QRG	dna polymerase iii
LPB138_10730	ENOG4105BZA	Phosphoglycerate kinase
LPB138_10740	ENOG4105C6Z	Gluconate
LPB138_10745	ENOG4105CPC	Aldo Keto reductase
LPB138_10770	ENOG4108UT2	hemolysin iii
LPB138_10780	ENOG4105DN3	alpha-2-macroglobulin domain protein
LPB138_10785	ENOG4108JQB	penicillin-binding protein 1C
LPB138_10790	ENOG4105DY9	regulatoR
LPB138_10795	ENOG4108HRK	Histidine kinase
LPB138_10800	ENOG4108HRK	Histidine kinase
LPB138_10825	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
LPB138_10830	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
LPB138_10850	ENOG4105D8V	Glucose sorbosone dehydrogenase
LPB138_10860	ENOG4105D8V	Glucose sorbosone dehydrogenase
LPB138_10865	ENOG4105C1G	acyl-Coa dehydrogenase
LPB138_10885	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
LPB138_10895	ENOG4105CN1	protease
LPB138_10910	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
LPB138_10915	ENOG4105C30	Nad-dependent epimerase dehydratase
LPB138_10920	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
LPB138_10930	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
LPB138_10935	ENOG4105C11	sulfate adenylyltransferase), subunit 2
LPB138_10940	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LPB138_10990	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
LPB138_10995	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB138_11005	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB138_11020	ENOG4105C12	Phosphoribosylglycinamide synthetase
LPB138_11025	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
LPB138_11030	ENOG4105BZU	Histidine kinase
LPB138_11035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB138_11055	ENOG4105C5H	ABC transporter
LPB138_11090	ENOG4108S4H	thioesterase Superfamily protein
LPB138_11110	ENOG4107VXZ	Hydrolase
LPB138_11125	ENOG4108JA2	transcriptioN-repair coupling factor
LPB138_11145	ENOG4107QKA	exodeoxyribonuclease V beta
LPB138_11170	ENOG4108IPT	Naphthoate synthase
LPB138_11175	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
LPB138_11180	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
LPB138_11185	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
LPB138_11190	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
LPB138_11200	ENOG4105FA0	parb-like partition protein
LPB138_11235	ENOG4108UUM	single-stranded DNA-binding protein
LPB138_11325	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
LPB138_11340	ENOG4105JD4	ATPase yjob
LPB138_11375	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
LPB138_11385	ENOG4105CY0	Metallo-Beta-Lactamase
LPB138_11410	ENOG4105C5I	Dehydrogenase
LPB138_11415	ENOG4107PU6	Membrane
LPB138_11420	ENOG4105CTQ	phosphohexokinase
LPB138_11430	ENOG4105CK2	sodium dicarboxylate symporter
LPB138_11435	ENOG4105EIE	fructose-bisphosphate aldolase
LPB138_11515	ENOG4108IJF	Heavy metal efflux pump, CzcA
LPB138_11525	ENOG4105E3B	Multicopper oxidase
LPB138_11560	ENOG4108M4U	conserved membrane protein
LPB138_11575	ENOG410624X	efflux transporter, rnd family, mfp subunit
LPB138_11605	ENOG4107QN2	dihydrolipoyl dehydrogenase
LPB138_11610	ENOG4105DC8	reductase
LPB138_11625	ENOG4105C59	p-type ATPase
LPB138_11670	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
LPB138_11685	ENOG4107QVM	von Willebrand factor, type A
LPB138_11690	ENOG4107QVM	von Willebrand factor, type A
LPB138_11725	ENOG4108V9Q	carbonic anhydrase
LPB138_11735	ENOG4105CHH	sulfate transporter
LPB138_11755	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
LPB138_11770	ENOG41080R2	UPF0102 protein
LPB138_11775	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
LPB138_11780	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
LPB138_11820	ENOG4105D3R	alkyl hydroperoxide reductase
LPB138_11840	ENOG4108UUM	single-stranded DNA-binding protein
LPB138_11865	ENOG4105CA9	Pyruvate kinase
LPB138_11875	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
LPB138_11880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
LPB138_11885	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
LPB138_11890	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
LPB138_11895	ENOG4108B1Q	Ribonuclease
LPB138_11925	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
LPB138_11950	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
LPB138_11960	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
LPB138_11970	ENOG4105CFH	Aspartokinase
LPB138_11975	ENOG4107T6F	Xaa-Pro aminopeptidase
LPB138_11990	ENOG4105E33	succinate dehydrogenase
LPB138_12040	ENOG4107QP8	phosphohexose isomerase
LPB138_12055	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
LPB138_12060	ENOG41083MR	nifu domain-containing protein
LPB138_12075	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
LPB138_12090	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
LPB138_12095	ENOG4109066	lysm domain bon superfamily protein
LPB138_12110	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
LPB138_12115	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
LPB138_12120	ENOG4105DR5	peptidase
LPB138_12135	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
LPB138_12140	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
LPB138_12145	ENOG4107T8J	thymidine kinase
LPB138_12170	ENOG4105EEQ	Na H antiporter
LPB138_12185	ENOG4105MJ2	Competence protein
LPB138_12200	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
LPB138_12220	ENOG4105C59	p-type ATPase
LPB138_12250	ENOG4105F8V	Hydrolase, tatD family
LPB138_12260	ENOG4105EMN	RNA polymerase sigma factor
LPB138_12285	ENOG4105C7S	Dehydrogenase
LPB138_12290	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
LPB138_12310	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
LPB138_12320	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
LPB138_12325	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
LPB138_12330	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
LPB138_12345	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
LPB138_12355	ENOG4105BZU	Histidine kinase
LPB138_12370	ENOG4108ZVT	methylmalonyl-coA epimerase
LPB138_12375	ENOG4107RJ9	Cell division protein FtsX
LPB138_12385	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
LPB138_12390	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
LPB138_12410	ENOG4105C9K	Endothelin-converting enzyme 1
LPB138_12415	ENOG4107QP8	phosphohexose isomerase
LPB138_12420	ENOG4105Y3E	Modulates RecA activity (By similarity)
LPB138_12465	ENOG4108R6K	riboflavin synthase, subunit alpha
LPB138_12470	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
LPB138_12480	ENOG4105WXV	50S ribosomal protein L32
LPB138_12485	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LPB138_12490	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
LPB138_12495	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
LPB138_12505	ENOG4105HDK	L-asparaginase
LPB138_12545	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LPB138_12550	ENOG4105C5S	asparaginyl-tRNA synthetase
LPB138_12565	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
LPB138_12570	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
LPB138_12580	ENOG4105E2D	ec 3.2.1.52
LPB138_12585	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
LPB138_12590	ENOG4108NEV	two component transcriptional regulator, LytTR family
LPB138_12600	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
LPB138_12605	ENOG4105CE9	30S ribosomal protein S2
LPB138_12610	ENOG4108UJD	30S ribosomal protein S9
LPB138_12615	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
LPB138_12625	ENOG4105K64	Glycosyl transferase, family 2
LPB138_12635	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
LPB138_12650	ENOG4105C2M	dna polymerase I
LPB138_12660	ENOG4105K63	Thioredoxin
LPB138_12680	ENOG4107YZX	Universal stress protein
LPB138_12685	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
LPB138_12690	ENOG4105CHV	Transcription elongation factor NusA
LPB138_12695	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
LPB138_12710	ENOG4107SFQ	iron-sulfur binding
LPB138_12735	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
LPB138_12740	ENOG4105BZ9	Cytochrome C oxidase, subunit I
LPB138_12745	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
LPB138_12750	ENOG4105C72	UPF0176 protein
LPB138_12780	ENOG4105C1J	atp-dependent rna helicase
LPB138_12790	ENOG4105CN1	protease
LPB138_12795	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
LPB138_12815	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
LPB138_12825	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
LPB138_12850	ENOG4107XVH	Transcriptional regulator
LPB138_12870	ENOG4105C0P	Mg chelatase subunit ChlI
LPB138_12875	ENOG4105KVH	Transcriptional regulator
LPB138_12880	ENOG4105CIS	alcohol dehydrogenase
LPB138_12910	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
LPB138_12925	ENOG4105EX0	alpha-galactosidase
LPB138_12945	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
LPB138_12965	ENOG4105CF7	AraC family transcriptional regulator
LPB138_12975	ENOG4108SC4	)-transporter
LPB138_12980	ENOG4105DDC	Oxidoreductase domain protein
LPB138_12985	ENOG4105CIB	oxidoreductase Domain protein
LPB138_13015	ENOG4107VXZ	Hydrolase
LPB138_13020	ENOG4105EE0	oxidoreductase
LPB138_13025	ENOG4107RUZ	Sss sodium solute transporter superfamily
LPB138_13085	ENOG4105CUJ	penicillin amidase
LPB138_13100	ENOG4105HY2	Glycosidase related protein
LPB138_13105	ENOG4105DFY	n-acylglucosamine 2-epimerase
LPB138_13115	ENOG4105TT1	Ragb susd domain-containing protein
LPB138_13135	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
LPB138_13145	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
LPB138_13150	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
LPB138_13155	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
LPB138_13165	ENOG4105CRQ	synthase (Component I)
LPB138_13175	ENOG4107QN2	dihydrolipoyl dehydrogenase
LPB138_13185	ENOG4105DGW	oligopeptidase A
LPB138_13190	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
LPB138_13195	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
LPB138_13205	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
LPB138_13215	ENOG4105BZU	Histidine kinase
LPB138_13230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
LPB138_13250	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
LPB138_13255	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
LPB138_13265	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LPB138_13290	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
LPB138_13300	ENOG4105CMR	udp-glucose 4-epimerase
LPB138_13310	ENOG4105C6T	cysteine synthase
LPB138_13315	ENOG4105D7W	serine acetyltransferase
LPB138_13320	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
LPB138_13330	ENOG4105C01	Dihydroxy-acid dehydratase
LPB138_13335	ENOG4105C7K	acetolactate synthase
LPB138_13340	ENOG4108ZP8	Acetolactate synthase small subunit
LPB138_13345	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
LPB138_13355	ENOG4105C7B	Threonine dehydratase
LPB138_13360	ENOG4105C26	Dehydrogenase
LPB138_13375	ENOG4108YBP	pseudouridine synthase
LPB138_13380	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
LPB138_13390	ENOG4107YM1	mraZ protein
LPB138_13395	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
LPB138_13405	ENOG4105CJN	penicillin-binding protein
LPB138_13410	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
LPB138_13415	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
LPB138_13420	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
LPB138_13425	ENOG4105CNI	cell division protein FtsW
LPB138_13430	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
LPB138_13435	ENOG4105DFU	Cell wall formation (By similarity)
LPB138_13445	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
LPB138_13450	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
LPB138_13455	ENOG4105KTH	gatB Yqey
LPB138_13500	ENOG4105DJV	ribulose-phosphate 3-epimerase
LPB138_13505	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LPB138_13535	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
LPB138_13540	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
LPB138_13550	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
LPB138_13555	ENOG4105D2N	Aldolase
LPB138_13565	ENOG4108RWN	rrna methyltransferase
LPB138_13575	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LPB138_13580	ENOG41083MR	nifu domain-containing protein
LPB138_13605	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
LPB138_13615	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
LPB138_13620	ENOG4105CNI	cell division protein FtsW
LPB138_13625	ENOG4105CJN	penicillin-binding protein
LPB138_13640	ENOG4105DFF	Rod shape-determining protein mreb
LPB138_13645	ENOG4105DC1	bifunctional purine biosynthesis protein purh
LPB138_13685	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
LPB138_13700	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
LPB138_13705	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
LPB138_13725	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LPB138_13730	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
LPB138_13750	ENOG4105E6M	Sulphatase-modifying factor protein
LPB138_13780	ENOG4105C5H	ABC transporter
LPB138_13785	ENOG4105K6H	D-cysteine desulfhydrase
LPB138_13790	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
LPB138_13815	ENOG4105CRK	lysyL-tRNA synthetase
LPB138_13845	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPB138_13850	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
LPB138_13855	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LPB138_13865	ENOG4105EEF	Alkane 1-monooxygenase
LPB138_13875	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LPB138_13880	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LPB138_13885	ENOG4105VRS	hydrolase family 18
LPB138_13900	ENOG4105CRE	cytochrome C
LPB138_13905	ENOG4105CPC	Aldo Keto reductase
LPB138_13920	ENOG4105D5P	Methylmalonyl-coA mutase
LPB138_13925	ENOG4105CMN	Methylmalonyl-coA mutase
LPB138_13935	ENOG4105DBI	uridine monophosphokinase
LPB138_13955	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LPB138_13960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB138_13970	ENOG4105C3M	thioredoxin reductase
LPB138_13990	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LPB138_13995	ENOG4105C9M	aspartyl-trna synthetase
LPB138_14010	ENOG4105CRQ	synthase (Component I)
LPB138_14015	ENOG4105DDQ	anthranilate synthase
LPB138_14020	ENOG4107RI6	Anthranilate phosphoribosyltransferase
LPB138_14025	ENOG4105DK0	Indole-3-glycerol phosphate synthase
LPB138_14030	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
LPB138_14035	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
LPB138_14040	ENOG4105CB5	ATP-dependent DNA helicase recG
LPB138_14075	ENOG4105CAK	Cell division ATP-binding protein ftsE
LPB138_14090	ENOG4106CC8	Bacterial inner membrane protein
LPB138_14095	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB138_14125	ENOG4105VRT	cytoplasmic protein
LPB138_14190	ENOG4105D05	Receptor
LPB138_14200	ENOG4105D3R	alkyl hydroperoxide reductase
LPB138_14205	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
LPB138_14215	ENOG4105NBK	UPF0345 protein
LPB138_14225	ENOG4108ZJ4	polysaccharide deacetylase
LPB138_14235	ENOG4108HRK	Histidine kinase
LPB138_14240	ENOG4108NEV	two component transcriptional regulator, LytTR family
LPB138_14250	ENOG4105KCK	Peptidoglycan-associated lipoprotein
LPB138_14265	ENOG4105DFU	Cell wall formation (By similarity)
LPB138_14270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
LPB138_14275	ENOG4105C1A	potassium transporter peripheral membrane
LPB138_14280	ENOG4105W5Q	DNA repair protein (RadC
LPB138_14300	ENOG4105CAQ	asparagine synthetase
LPB138_14330	ENOG4105D1H	recombination factor protein RarA
LPB138_14340	ENOG4105C2N	RNA methyltransferase TrmH family group 3
LPB138_14380	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
LPB138_14385	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
LPB138_14390	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
LPB138_14395	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
LPB138_14400	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
LPB138_14405	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
LPB138_14410	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
LPB138_14415	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPB138_14420	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
LPB138_14425	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
LPB138_14430	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
LPB138_14435	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
LPB138_14440	ENOG4105WNB	50s ribosomal protein l29
LPB138_14445	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
LPB138_14450	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
LPB138_14455	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
LPB138_14460	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPB138_14465	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
LPB138_14470	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
LPB138_14475	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
LPB138_14480	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
LPB138_14485	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
LPB138_14490	ENOG41084HK	50S ribosomal protein L30
LPB138_14495	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
LPB138_14500	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
LPB138_14505	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
LPB138_14510	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPB138_14515	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
LPB138_14520	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
LPB138_14525	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB138_14530	ENOG4108ZT0	50S ribosomal protein l17
LPB138_14540	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
LPB138_14545	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
LPB138_14565	ENOG4105D7N	magnesium and cobalt transport protein CorA
LPB138_14630	ENOG4105C01	Dihydroxy-acid dehydratase
LPB138_14635	ENOG4105C6Z	Gluconate
LPB138_14640	ENOG4105ERH	Fumarylacetoacetate hydrolase
LPB138_14680	ENOG4105EMN	RNA polymerase sigma factor
LPB138_14700	ENOG4105E2D	ec 3.2.1.52
LPB138_14705	ENOG4105DHF	Membrane
LPB138_14720	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LPB138_14730	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
LPB138_14745	ENOG4105CXT	aspartate transcarbamylase
LPB138_14750	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
LPB138_14770	ENOG4105E2X	shikimate dehydrogenase
LPB138_14790	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
LPB138_14795	ENOG4105KNE	Phosphatidate cytidylyltransferase
LPB138_14805	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
LPB138_14810	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
LPB138_14825	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
LPB138_14835	ENOG4105CHH	sulfate transporter
LPB138_14840	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
LPB138_14845	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
LPB138_14865	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
LPB138_14870	ENOG4105CPF	Cell wall formation (By similarity)
LPB138_14880	ENOG4105C34	Pseudouridine synthase
LPB138_14910	ENOG4105D1Q	UPF0246 protein
LPB138_14920	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
LPB138_14930	ENOG4105E0R	Deoxyhypusine synthase
LPB138_14945	ENOG4105CFG	Acts as a chaperone (By similarity)
LPB138_14950	ENOG4105EA8	2-Nitropropane dioxygenase
LPB138_14975	ENOG4105C1G	acyl-Coa dehydrogenase
LPB138_14980	ENOG4105CHU	acetyl-coa acetyltransferase
LPB138_14995	ENOG4108IUX	(ABC) transporter
LPB138_15000	ENOG4105RHA	ABC transporter, permease
LPB138_15005	ENOG4105EGS	Mechanosensitive ion channel
LPB138_15015	ENOG4105CSR	polyphosphate kinase 2
LPB138_15020	ENOG4105UMD	exodeoxyribonuclease X
LPB138_15030	ENOG4105D17	glycoside hydrolase, family 3 domain protein
LPB138_15035	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
LPB138_15040	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
LPB138_15045	ENOG4105II7	pyrroline-5-carboxylate reductase
LPB138_15065	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
LPB138_15100	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
LPB138_15135	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPB138_15145	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
LPB138_15150	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
LPB138_15170	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
LPB138_15185	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
LPB138_15195	ENOG4108TGP	Thioesterase superfamily protein