locus-tag	class	description
DSM104440_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSM104440_00002	COG0592	DNA-directed DNA polymerase activity
DSM104440_00005	COG0758	DNA mediated transformation
DSM104440_00006	COG3942	CHAP domain
DSM104440_00006	COG1388	LysM domain
DSM104440_00007	COG0242	peptide deformylase activity
DSM104440_00008	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104440_00010	COG5000	phosphorelay sensor kinase activity
DSM104440_00011	COG2204	response regulator
DSM104440_00014	COG4608	Belongs to the ABC transporter superfamily
DSM104440_00015	COG0444	Belongs to the ABC transporter superfamily
DSM104440_00016	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104440_00017	COG0601	transmembrane transport
DSM104440_00018	COG0747	negative chemotaxis
DSM104440_00030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSM104440_00031	COG2863	cytochrome
DSM104440_00033	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSM104440_00034	COG0352	thiamine-phosphate diphosphorylase activity
DSM104440_00035	COG0351	phosphomethylpyrimidine kinase
DSM104440_00040	COG0840	transmembrane signaling receptor activity
DSM104440_00041	COG0784	Response regulator, receiver
DSM104440_00041	COG2198	Histidine kinase
DSM104440_00041	COG0643	Histidine kinase
DSM104440_00042	COG3507	Belongs to the glycosyl hydrolase 43 family
DSM104440_00044	COG0596	Alpha beta hydrolase
DSM104440_00046	COG1968	undecaprenyl-diphosphatase activity
DSM104440_00049	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSM104440_00052	COG1131	(ABC) transporter
DSM104440_00053	COG0842	Transport permease protein
DSM104440_00054	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104440_00057	COG0859	PFAM glycosyl transferase family 9
DSM104440_00067	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DSM104440_00070	COG1137	ATPase activity
DSM104440_00071	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DSM104440_00072	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSM104440_00073	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104440_00074	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DSM104440_00075	COG1660	Displays ATPase and GTPase activities
DSM104440_00079	COG3275	phosphorelay sensor kinase activity
DSM104440_00080	COG3279	Response regulator of the LytR AlgR family
DSM104440_00082	COG2022	thiamine diphosphate biosynthetic process
DSM104440_00084	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSM104440_00086	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM104440_00087	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSM104440_00088	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSM104440_00089	COG0631	protein serine/threonine phosphatase activity
DSM104440_00090	COG0515	serine threonine protein kinase
DSM104440_00090	COG2815	serine threonine protein kinase
DSM104440_00091	COG1561	YicC-like family, N-terminal region
DSM104440_00092	COG0194	GDP metabolic process
DSM104440_00093	COG1758	RNA polymerase activity
DSM104440_00094	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM104440_00096	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSM104440_00097	COG3161	chorismate lyase activity
DSM104440_00098	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSM104440_00099	COG2249	NAD(P)H dehydrogenase (quinone) activity
DSM104440_00101	COG0183	Belongs to the thiolase family
DSM104440_00105	COG0659	secondary active sulfate transmembrane transporter activity
DSM104440_00114	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
DSM104440_00129	COG4974	Belongs to the 'phage' integrase family
DSM104440_00135	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104440_00136	COG1960	acyl-CoA dehydrogenase activity
DSM104440_00138	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00139	COG0183	Belongs to the thiolase family
DSM104440_00140	COG1024	Enoyl-CoA hydratase
DSM104440_00140	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104440_00142	COG1137	ATPase activity
DSM104440_00144	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104440_00145	COG0683	leucine binding
DSM104440_00146	COG1960	acyl-CoA dehydrogenase activity
DSM104440_00147	COG1960	acyl-CoA dehydrogenase activity
DSM104440_00148	COG2045	Belongs to the ComB family
DSM104440_00149	COG0300	oxidoreductase activity
DSM104440_00151	COG1414	Transcriptional regulator
DSM104440_00156	COG1530	ribonuclease E activity
DSM104440_00157	COG0424	maF-like protein
DSM104440_00159	COG0799	negative regulation of ribosome biogenesis
DSM104440_00160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSM104440_00161	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSM104440_00164	COG0495	leucyl-tRNA aminoacylation
DSM104440_00170	COG0210	DNA helicase
DSM104440_00173	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSM104440_00176	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104440_00176	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104440_00177	COG0009	L-threonylcarbamoyladenylate synthase
DSM104440_00182	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSM104440_00182	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSM104440_00184	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104440_00191	COG0138	bifunctional purine biosynthesis protein purh
DSM104440_00192	COG0151	Belongs to the GarS family
DSM104440_00200	COG0515	serine threonine protein kinase
DSM104440_00200	COG2815	serine threonine protein kinase
DSM104440_00208	COG4654	Cytochrome c, class I
DSM104440_00209	COG1331	Highly conserved protein containing a thioredoxin domain
DSM104440_00212	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104440_00213	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DSM104440_00219	COG0667	Aldo Keto reductase
DSM104440_00225	COG0129	dihydroxy-acid dehydratase activity
DSM104440_00227	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSM104440_00232	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104440_00241	COG2197	response regulator
DSM104440_00243	COG4585	Histidine kinase
DSM104440_00245	COG5487	UPF0391 membrane protein
DSM104440_00248	COG4575	ribosome binding
DSM104440_00249	COG2823	Periplasmic or secreted lipoprotein
DSM104440_00252	COG3237	CsbD-like
DSM104440_00253	COG0628	permease
DSM104440_00256	COG0745	RESPONSE REGULATOR receiver
DSM104440_00257	COG2205	protein histidine kinase activity
DSM104440_00258	COG5001	Diguanylate cyclase
DSM104440_00261	COG0626	cystathionine gamma-synthase activity
DSM104440_00262	COG3001	Fructosamine kinase
DSM104440_00274	COG2251	uridine kinase activity
DSM104440_00274	COG0195	Participates in both transcription termination and antitermination
DSM104440_00305	COG1435	thymidine kinase activity
DSM104440_00307	COG0346	lactoylglutathione lyase activity
DSM104440_00315	COG0640	Transcriptional regulator
DSM104440_00350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DSM104440_00350	COG0456	acetyltransferase
DSM104440_00357	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSM104440_00358	COG0454	-acetyltransferase
DSM104440_00361	COG2203	Gaf domain
DSM104440_00361	COG5001	Diguanylate cyclase
DSM104440_00361	COG3706	GGDEF domain
DSM104440_00361	COG4251	negative regulation of phosphorylation
DSM104440_00362	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00374	COG0681	Belongs to the peptidase S26 family
DSM104440_00375	COG1120	ATPase activity
DSM104440_00376	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM104440_00377	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSM104440_00378	COG1305	Transglutaminase-like
DSM104440_00379	COG1910	domain protein
DSM104440_00384	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DSM104440_00385	COG4149	molybdate abc transporter
DSM104440_00386	COG0725	ABC transporter, periplasmic molybdate-binding protein
DSM104440_00388	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DSM104440_00391	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSM104440_00392	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DSM104440_00396	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DSM104440_00397	COG0237	dephospho-CoA kinase activity
DSM104440_00398	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DSM104440_00399	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DSM104440_00401	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DSM104440_00402	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSM104440_00404	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DSM104440_00406	COG1845	cytochrome c oxidase, subunit III
DSM104440_00410	COG0109	protoheme IX farnesyltransferase activity
DSM104440_00411	COG1999	signal sequence binding
DSM104440_00413	COG2177	Part of the ABC transporter FtsEX involved in
DSM104440_00414	COG2884	Cell division ATP-binding protein ftsE
DSM104440_00416	COG0742	ribosomal rna small subunit methyltransferase
DSM104440_00417	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DSM104440_00418	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM104440_00420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DSM104440_00422	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DSM104440_00423	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSM104440_00425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSM104440_00426	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DSM104440_00427	COG0193	aminoacyl-tRNA hydrolase activity
DSM104440_00428	COG0012	GTP binding
DSM104440_00436	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104440_00440	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104440_00444	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DSM104440_00446	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104440_00452	COG1702	phosphate starvation-inducible protein PhoH
DSM104440_00453	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DSM104440_00454	COG4535	Mg2 and Co2 transporter CorC
DSM104440_00455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSM104440_00459	COG0752	glycyl-tRNA synthetase alpha subunit
DSM104440_00460	COG0751	glycine-tRNA ligase activity
DSM104440_00461	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSM104440_00465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSM104440_00466	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DSM104440_00467	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104440_00468	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DSM104440_00471	COG0006	proline dipeptidase activity
DSM104440_00472	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104440_00473	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104440_00474	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSM104440_00475	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DSM104440_00476	COG2967	ApaG domain
DSM104440_00477	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM104440_00480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSM104440_00481	COG0134	indole-3-glycerol-phosphate synthase activity
DSM104440_00483	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DSM104440_00484	COG1765	OsmC-like protein
DSM104440_00485	COG0628	permease
DSM104440_00486	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSM104440_00487	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSM104440_00488	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DSM104440_00491	COG0316	Belongs to the HesB IscA family
DSM104440_00492	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DSM104440_00493	COG4942	peptidase
DSM104440_00494	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSM104440_00499	COG3795	YCII-related domain
DSM104440_00505	COG0308	aminopeptidase N
DSM104440_00506	COG0513	Belongs to the DEAD box helicase family
DSM104440_00509	COG1053	succinate dehydrogenase
DSM104440_00511	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104440_00516	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM104440_00517	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DSM104440_00518	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSM104440_00519	COG2224	Isocitrate lyase
DSM104440_00521	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM104440_00531	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104440_00531	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DSM104440_00532	COG3118	belongs to the thioredoxin family
DSM104440_00541	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104440_00546	COG2391	methyltransferase activity
DSM104440_00548	COG3447	MASE1 domain protein
DSM104440_00548	COG5002	protein histidine kinase activity
DSM104440_00548	COG5001	Diguanylate cyclase
DSM104440_00549	COG1127	ABC transporter
DSM104440_00551	COG1595	DNA-templated transcription, initiation
DSM104440_00557	COG3011	Protein conserved in bacteria
DSM104440_00559	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSM104440_00562	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00567	COG0129	dihydroxy-acid dehydratase activity
DSM104440_00569	COG0488	(ABC) transporter
DSM104440_00575	COG1408	metallophosphoesterase
DSM104440_00578	COG5487	UPF0391 membrane protein
DSM104440_00583	COG0747	negative chemotaxis
DSM104440_00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_00586	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSM104440_00588	COG0861	Integral membrane protein TerC family
DSM104440_00589	COG4452	Inner membrane protein CreD
DSM104440_00593	COG0745	RESPONSE REGULATOR receiver
DSM104440_00595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104440_00601	COG0484	heat shock protein binding
DSM104440_00604	COG3384	dioxygenase
DSM104440_00606	COG0793	Belongs to the peptidase S41A family
DSM104440_00606	COG3409	Peptidoglycan-binding domain 1 protein
DSM104440_00610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSM104440_00614	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DSM104440_00616	COG1376	ErfK ybiS ycfS ynhG family protein
DSM104440_00617	COG0277	FAD linked oxidase domain protein
DSM104440_00618	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DSM104440_00620	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSM104440_00621	COG0792	nuclease activity
DSM104440_00622	COG3107	peptidoglycan biosynthetic process
DSM104440_00624	COG0418	dihydroorotase activity
DSM104440_00634	COG2001	Belongs to the MraZ family
DSM104440_00635	COG0275	rRNA processing
DSM104440_00636	COG3116	cell division
DSM104440_00638	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSM104440_00639	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSM104440_00640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104440_00642	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSM104440_00643	COG0772	Belongs to the SEDS family
DSM104440_00644	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM104440_00645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104440_00646	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSM104440_00647	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM104440_00648	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DSM104440_00653	COG0739	heme binding
DSM104440_00654	COG0653	protein targeting
DSM104440_00655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSM104440_00656	COG2226	methyltransferase
DSM104440_00658	COG0494	nUDIX hydrolase
DSM104440_00659	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DSM104440_00660	COG1116	anion transmembrane transporter activity
DSM104440_00660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104440_00661	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104440_00662	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104440_00664	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DSM104440_00665	COG2226	methyltransferase
DSM104440_00666	COG2267	carboxylic ester hydrolase activity
DSM104440_00667	COG0156	8-amino-7-oxononanoate synthase activity
DSM104440_00668	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSM104440_00669	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DSM104440_00670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSM104440_00681	COG3188	usher protein
DSM104440_00683	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSM104440_00685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DSM104440_00690	COG0588	phosphoglycerate mutase activity
DSM104440_00691	COG4942	peptidase
DSM104440_00692	COG0793	Belongs to the peptidase S41A family
DSM104440_00693	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSM104440_00697	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSM104440_00698	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSM104440_00699	COG1610	YqeY-like protein
DSM104440_00702	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104440_00707	COG1832	CoA-binding protein
DSM104440_00709	COG0330	HflC and HflK could
DSM104440_00715	COG1960	acyl-CoA dehydrogenase activity
DSM104440_00716	COG0183	Belongs to the thiolase family
DSM104440_00722	COG1022	Amp-dependent synthetase and ligase
DSM104440_00723	COG1024	Enoyl-CoA hydratase
DSM104440_00724	COG2130	NADP-dependent
DSM104440_00726	COG1024	Enoyl-CoA hydratase
DSM104440_00726	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104440_00728	COG0183	Belongs to the thiolase family
DSM104440_00737	COG0678	peroxiredoxin activity
DSM104440_00738	COG1280	lysine exporter protein (LysE YggA)
DSM104440_00739	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSM104440_00742	COG1956	GAF domain-containing protein
DSM104440_00755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DSM104440_00756	COG2815	serine threonine protein kinase
DSM104440_00756	COG0515	serine threonine protein kinase
DSM104440_00759	COG5002	protein histidine kinase activity
DSM104440_00761	COG0784	Response regulator, receiver
DSM104440_00762	COG0277	FAD linked oxidase domain protein
DSM104440_00763	COG0277	FAD linked oxidase domain protein
DSM104440_00764	COG0277	FAD linked oxidase domain protein
DSM104440_00765	COG0247	lactate metabolic process
DSM104440_00767	COG0254	rRNA binding
DSM104440_00769	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSM104440_00771	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSM104440_00773	COG4251	negative regulation of phosphorylation
DSM104440_00774	COG0784	Response regulator, receiver
DSM104440_00776	COG1294	oxidase, subunit
DSM104440_00777	COG1271	oxidase subunit
DSM104440_00779	COG1074	ATP-dependent DNA helicase activity
DSM104440_00784	COG2267	carboxylic ester hydrolase activity
DSM104440_00785	COG3132	Protein of unknown function, DUF480
DSM104440_00790	COG0583	DNA-binding transcription factor activity
DSM104440_00791	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSM104440_00797	COG2186	Transcriptional regulator
DSM104440_00798	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104440_00802	COG0756	dUTP diphosphatase activity
DSM104440_00803	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSM104440_00804	COG2003	Belongs to the UPF0758 family
DSM104440_00805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSM104440_00806	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSM104440_00807	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSM104440_00808	COG0840	transmembrane signaling receptor activity
DSM104440_00811	COG3264	Mechanosensitive ion channel
DSM104440_00811	COG1511	domain protein
DSM104440_00812	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM104440_00812	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSM104440_00814	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSM104440_00815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSM104440_00816	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSM104440_00817	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSM104440_00819	COG0617	tRNA 3'-terminal CCA addition
DSM104440_00821	COG1428	Deoxynucleoside kinase
DSM104440_00822	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSM104440_00823	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSM104440_00824	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DSM104440_00826	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104440_00832	COG0662	Cupin 2, conserved barrel domain protein
DSM104440_00833	COG1850	ribulose-bisphosphate carboxylase activity
DSM104440_00837	COG0243	molybdopterin cofactor binding
DSM104440_00838	COG2146	nitrite reductase [NAD(P)H] activity
DSM104440_00839	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSM104440_00840	COG1116	anion transmembrane transporter activity
DSM104440_00841	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104440_00842	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104440_00843	COG3707	response regulator
DSM104440_00845	COG2274	protein secretion by the type I secretion system
DSM104440_00846	COG2274	protein secretion by the type I secretion system
DSM104440_00853	COG4771	TonB-dependent receptor
DSM104440_00854	COG1609	Transcriptional regulator
DSM104440_00857	COG0395	ABC-type sugar transport system, permease component
DSM104440_00858	COG2723	6-phospho-beta-galactosidase activity
DSM104440_00862	COG0583	DNA-binding transcription factor activity
DSM104440_00865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DSM104440_00867	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSM104440_00870	COG0577	efflux transmembrane transporter activity
DSM104440_00870	COG1136	(ABC) transporter
DSM104440_00874	COG3655	Transcriptional regulator
DSM104440_00877	COG0697	spore germination
DSM104440_00880	COG0354	folic acid binding
DSM104440_00882	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSM104440_00882	COG0047	phosphoribosylformylglycinamidine synthase activity
DSM104440_00890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104440_00891	COG0271	Belongs to the BolA IbaG family
DSM104440_00892	COG2917	probably involved in intracellular septation
DSM104440_00894	COG0613	PHP domain protein
DSM104440_00895	COG0009	L-threonylcarbamoyladenylate synthase
DSM104440_00896	COG1994	Peptidase M50
DSM104440_00897	COG0180	Tryptophanyl-tRNA synthetase
DSM104440_00899	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DSM104440_00900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSM104440_00903	COG0583	DNA-binding transcription factor activity
DSM104440_00906	COG1335	isochorismatase
DSM104440_00908	COG3795	YCII-related domain
DSM104440_00910	COG0259	pyridoxamine-phosphate oxidase activity
DSM104440_00916	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104440_00920	COG2171	N-acyltransferase activity
DSM104440_00921	COG0436	Aminotransferase
DSM104440_00922	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104440_00923	COG0463	Glycosyl transferase, family 2
DSM104440_00925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSM104440_00929	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSM104440_00930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSM104440_00931	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSM104440_00933	COG0242	peptide deformylase activity
DSM104440_00938	COG0024	Methionine aminopeptidase
DSM104440_00939	COG0052	Belongs to the universal ribosomal protein uS2 family
DSM104440_00940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DSM104440_00941	COG0528	UMP kinase activity
DSM104440_00942	COG0233	cytoplasmic translational termination
DSM104440_00943	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSM104440_00944	COG0575	Belongs to the CDS family
DSM104440_00949	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104440_00950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM104440_00951	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104440_00952	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104440_00953	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSM104440_00954	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104440_00957	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSM104440_00958	COG3240	lipase activity
DSM104440_00958	COG4625	pathogenesis
DSM104440_00959	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DSM104440_00961	COG2153	protein acetylation
DSM104440_00963	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_00964	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DSM104440_00965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104440_00966	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM104440_00968	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSM104440_00982	COG3706	GGDEF domain
DSM104440_00987	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DSM104440_00988	COG1053	succinate dehydrogenase
DSM104440_00991	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM104440_00992	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSM104440_00993	COG0493	'glutamate synthase
DSM104440_00994	COG0281	malic enzyme
DSM104440_01000	COG1007	ATP synthesis coupled electron transport
DSM104440_01002	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DSM104440_01003	COG0713	ATP synthesis coupled electron transport
DSM104440_01005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_01006	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSM104440_01007	COG1034	ATP synthesis coupled electron transport
DSM104440_01010	COG0649	NAD binding
DSM104440_01011	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_01012	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_01015	COG2267	carboxylic ester hydrolase activity
DSM104440_01016	COG3278	Belongs to the heme-copper respiratory oxidase family
DSM104440_01024	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM104440_01024	COG0045	succinate-CoA ligase (ADP-forming) activity
DSM104440_01024	COG1042	CoA-binding domain protein
DSM104440_01028	COG0589	response to stress
DSM104440_01030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104440_01031	COG2201	protein-glutamate methylesterase activity
DSM104440_01034	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM104440_01041	COG2070	2-Nitropropane dioxygenase
DSM104440_01045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSM104440_01050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSM104440_01056	COG4654	Cytochrome c, class I
DSM104440_01057	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104440_01060	COG1272	protein, Hemolysin III
DSM104440_01062	COG3154	lipid carrier protein
DSM104440_01063	COG0826	peptidase U32
DSM104440_01064	COG0826	peptidase U32
DSM104440_01065	COG2832	Protein of unknown function (DUF454)
DSM104440_01066	COG1959	2 iron, 2 sulfur cluster binding
DSM104440_01067	COG3256	nitric oxide reductase
DSM104440_01069	COG2151	metal-sulfur cluster biosynthetic enzyme
DSM104440_01070	COG3005	denitrification pathway
DSM104440_01071	COG3043	anaerobic respiration
DSM104440_01072	COG0243	molybdopterin cofactor binding
DSM104440_01073	COG3062	negative regulation of establishment of protein localization
DSM104440_01078	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104440_01088	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSM104440_01089	COG0670	Belongs to the BI1 family
DSM104440_01094	COG5001	Diguanylate cyclase
DSM104440_01096	COG1505	serine-type exopeptidase activity
DSM104440_01101	COG0784	Response regulator, receiver
DSM104440_01101	COG4191	Histidine kinase
DSM104440_01110	COG0069	glutamate synthase activity
DSM104440_01113	COG0786	glutamate:sodium symporter activity
DSM104440_01119	COG1612	heme a metabolic process
DSM104440_01123	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_01124	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104440_01127	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104440_01130	COG1137	ATPase activity
DSM104440_01132	COG0488	(ABC) transporter
DSM104440_01137	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104440_01141	COG1012	belongs to the aldehyde dehydrogenase family
DSM104440_01142	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM104440_01145	COG2267	carboxylic ester hydrolase activity
DSM104440_01146	COG2066	Belongs to the glutaminase family
DSM104440_01149	COG1228	amidohydrolase
DSM104440_01152	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSM104440_01154	COG1129	ABC transporter
DSM104440_01156	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104440_01158	COG3800	Transcriptional regulator
DSM104440_01158	COG1396	sequence-specific DNA binding
DSM104440_01161	COG5002	protein histidine kinase activity
DSM104440_01163	COG1283	sodium-dependent phosphate transmembrane transporter activity
DSM104440_01164	COG1012	belongs to the aldehyde dehydrogenase family
DSM104440_01171	COG0583	DNA-binding transcription factor activity
DSM104440_01172	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM104440_01173	COG3842	ATPase activity
DSM104440_01175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104440_01178	COG2226	methyltransferase
DSM104440_01179	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104440_01180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DSM104440_01181	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104440_01184	COG2850	peptidyl-arginine hydroxylation
DSM104440_01185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104440_01186	COG1047	Peptidyl-prolyl cis-trans
DSM104440_01188	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSM104440_01190	COG1652	LysM domain
DSM104440_01192	COG1252	NADH dehydrogenase
DSM104440_01193	COG0483	inositol monophosphate 1-phosphatase activity
DSM104440_01194	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DSM104440_01196	COG1045	serine acetyltransferase
DSM104440_01198	COG1104	cysteine desulfurase activity
DSM104440_01199	COG0822	iron-sulfur transferase activity
DSM104440_01200	COG0316	Belongs to the HesB IscA family
DSM104440_01201	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSM104440_01202	COG0443	Heat shock 70 kDa protein
DSM104440_01205	COG0683	leucine binding
DSM104440_01207	COG2204	response regulator
DSM104440_01209	COG2205	protein histidine kinase activity
DSM104440_01211	COG0560	Phosphoserine phosphatase
DSM104440_01212	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSM104440_01213	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DSM104440_01213	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DSM104440_01218	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104440_01220	COG5002	protein histidine kinase activity
DSM104440_01221	COG4566	intracellular signal transduction
DSM104440_01225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSM104440_01228	COG0745	RESPONSE REGULATOR receiver
DSM104440_01234	COG0028	Belongs to the TPP enzyme family
DSM104440_01236	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSM104440_01237	COG0688	phosphatidylethanolamine metabolic process
DSM104440_01238	COG1183	phosphatidylcholine synthase activity
DSM104440_01239	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104440_01241	COG0656	L-ascorbic acid biosynthetic process
DSM104440_01244	COG0625	glutathione transferase activity
DSM104440_01245	COG0482	sulfurtransferase activity
DSM104440_01248	COG0538	isocitrate dehydrogenase activity
DSM104440_01249	COG1278	Cold shock
DSM104440_01250	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DSM104440_01251	COG0542	response to heat
DSM104440_01253	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSM104440_01254	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM104440_01255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM104440_01257	COG0433	COG0433 Predicted ATPase
DSM104440_01258	COG0217	transcriptional regulatory protein
DSM104440_01260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSM104440_01261	COG0632	four-way junction helicase activity
DSM104440_01262	COG2255	four-way junction helicase activity
DSM104440_01263	COG0824	Thioesterase
DSM104440_01265	COG0848	biopolymer transport protein
DSM104440_01267	COG0823	Involved in the tonB-independent uptake of proteins
DSM104440_01270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DSM104440_01277	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DSM104440_01282	COG0195	Participates in both transcription termination and antitermination
DSM104440_01282	COG2251	uridine kinase activity
DSM104440_01283	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSM104440_01284	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DSM104440_01285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSM104440_01286	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSM104440_01287	COG1185	polyribonucleotide nucleotidyltransferase activity
DSM104440_01291	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSM104440_01293	COG2914	Belongs to the UPF0125 (RnfH) family
DSM104440_01299	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104440_01299	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSM104440_01300	COG4677	pectinesterase activity
DSM104440_01301	COG3618	amidohydrolase
DSM104440_01303	COG1393	Belongs to the ArsC family
DSM104440_01304	COG3706	GGDEF domain
DSM104440_01304	COG4251	negative regulation of phosphorylation
DSM104440_01304	COG5001	Diguanylate cyclase
DSM104440_01304	COG2203	Gaf domain
DSM104440_01305	COG2205	protein histidine kinase activity
DSM104440_01305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104440_01311	COG1254	Belongs to the acylphosphatase family
DSM104440_01314	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104440_01314	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104440_01315	COG0489	protein tyrosine kinase activity
DSM104440_01316	COG0717	Belongs to the dCTP deaminase family
DSM104440_01317	COG0019	diaminopimelate decarboxylase activity
DSM104440_01324	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DSM104440_01329	COG1355	regulation of microtubule-based process
DSM104440_01330	COG3885	ferrous iron binding
DSM104440_01330	COG2078	PFAM AMMECR1 domain protein
DSM104440_01332	COG1162	GTPase activity
DSM104440_01333	COG2154	pterin-4-alpha-carbinolamine dehydratase
DSM104440_01334	COG0501	Belongs to the peptidase M48B family
DSM104440_01335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DSM104440_01337	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DSM104440_01341	COG1653	transport
DSM104440_01342	COG1175	transmembrane transport
DSM104440_01343	COG0395	ABC-type sugar transport system, permease component
DSM104440_01346	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
DSM104440_01348	COG1546	Belongs to the CinA family
DSM104440_01349	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSM104440_01350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSM104440_01351	COG2137	regulation of response to DNA damage stimulus
DSM104440_01353	COG1335	isochorismatase
DSM104440_01357	COG1872	DUF167
DSM104440_01359	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSM104440_01360	COG2816	NAD+ diphosphatase activity
DSM104440_01364	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104440_01365	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104440_01366	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DSM104440_01370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104440_01371	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSM104440_01372	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSM104440_01377	COG0577	efflux transmembrane transporter activity
DSM104440_01377	COG1136	(ABC) transporter
DSM104440_01378	COG1136	(ABC) transporter
DSM104440_01378	COG0577	efflux transmembrane transporter activity
DSM104440_01379	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_01382	COG4783	chaperone-mediated protein folding
DSM104440_01383	COG0315	cyclic pyranopterin monophosphate synthase activity
DSM104440_01386	COG0425	Belongs to the sulfur carrier protein TusA family
DSM104440_01387	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_01389	COG0525	valine-tRNA ligase activity
DSM104440_01392	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104440_01400	COG0543	2 iron, 2 sulfur cluster binding
DSM104440_01400	COG0493	'glutamate synthase
DSM104440_01401	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DSM104440_01403	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSM104440_01406	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSM104440_01407	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DSM104440_01408	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DSM104440_01409	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSM104440_01417	COG2205	protein histidine kinase activity
DSM104440_01421	COG1585	Membrane protein implicated in regulation of membrane protease activity
DSM104440_01422	COG2268	Band 7 protein
DSM104440_01424	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104440_01427	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104440_01430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104440_01432	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104440_01433	COG1609	Transcriptional regulator
DSM104440_01435	COG2755	lipolytic protein G-D-S-L family
DSM104440_01440	COG0673	inositol 2-dehydrogenase activity
DSM104440_01443	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSM104440_01445	COG3023	N-Acetylmuramoyl-L-alanine amidase
DSM104440_01446	COG4166	transmembrane transport
DSM104440_01447	COG2715	membrane protein required for spore maturation
DSM104440_01451	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104440_01451	COG1672	PFAM Archaeal ATPase
DSM104440_01453	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSM104440_01454	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSM104440_01455	COG0346	lactoylglutathione lyase activity
DSM104440_01456	COG0281	malic enzyme
DSM104440_01456	COG0280	phosphate acetyltransferase
DSM104440_01467	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSM104440_01468	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSM104440_01470	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DSM104440_01478	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104440_01480	COG1278	Cold shock
DSM104440_01482	COG0066	3-isopropylmalate dehydratase activity
DSM104440_01483	COG0473	3-isopropylmalate dehydrogenase activity
DSM104440_01487	COG0135	phosphoribosylanthranilate isomerase activity
DSM104440_01488	COG0133	tryptophan synthase activity
DSM104440_01489	COG0159	tryptophan synthase activity
DSM104440_01490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DSM104440_01491	COG0285	dihydrofolate synthase activity
DSM104440_01502	COG0215	cysteine-tRNA ligase activity
DSM104440_01504	COG0683	leucine binding
DSM104440_01506	COG0443	Heat shock 70 kDa protein
DSM104440_01507	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSM104440_01508	COG1950	PFAM Membrane protein of
DSM104440_01509	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DSM104440_01510	COG1420	regulation of RNA biosynthetic process
DSM104440_01511	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSM104440_01512	COG0497	DNA recombination
DSM104440_01516	COG0400	carboxylic ester hydrolase activity
DSM104440_01517	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSM104440_01518	COG3028	Belongs to the UPF0307 family
DSM104440_01519	COG0312	modulator of DNA gyrase
DSM104440_01520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104440_01522	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSM104440_01524	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104440_01528	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM104440_01529	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM104440_01530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104440_01530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104440_01533	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DSM104440_01534	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM104440_01535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DSM104440_01536	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DSM104440_01537	COG0584	glycerophosphoryl diester phosphodiesterase
DSM104440_01542	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DSM104440_01542	COG0678	peroxiredoxin activity
DSM104440_01543	COG0583	DNA-binding transcription factor activity
DSM104440_01544	COG1309	transcriptional regulator
DSM104440_01550	COG1592	Rubrerythrin
DSM104440_01554	COG1228	amidohydrolase
DSM104440_01557	COG2264	protein methyltransferase activity
DSM104440_01559	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DSM104440_01570	COG0393	Putative heavy-metal-binding
DSM104440_01578	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DSM104440_01579	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DSM104440_01580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSM104440_01580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DSM104440_01581	COG0666	response to abiotic stimulus
DSM104440_01582	COG1174	glycine betaine transport
DSM104440_01585	COG2986	histidine ammonia-lyase
DSM104440_01594	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_01595	COG0129	dihydroxy-acid dehydratase activity
DSM104440_01596	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104440_01597	COG3842	ATPase activity
DSM104440_01599	COG1175	transmembrane transport
DSM104440_01601	COG3833	ABC-type maltose transport systems, permease component
DSM104440_01603	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DSM104440_01604	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM104440_01606	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104440_01607	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104440_01608	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSM104440_01609	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_01612	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSM104440_01613	COG2721	sulfolactate sulfo-lyase activity
DSM104440_01614	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104440_01615	COG0589	response to stress
DSM104440_01617	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM104440_01619	COG1320	monovalent cation:proton antiporter activity
DSM104440_01620	COG2212	antiporter activity
DSM104440_01621	COG1863	multisubunit Na H antiporter MnhE subunit
DSM104440_01622	COG0651	ATP synthesis coupled electron transport
DSM104440_01623	COG1006	Multisubunit Na H antiporter MnhC subunit
DSM104440_01624	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DSM104440_01624	COG2111	Na H antiporter
DSM104440_01625	COG1253	flavin adenine dinucleotide binding
DSM104440_01631	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104440_01635	COG4771	TonB-dependent receptor
DSM104440_01639	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104440_01651	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSM104440_01653	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DSM104440_01659	COG2358	TRAP transporter, solute receptor (TAXI family
DSM104440_01660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSM104440_01679	COG0697	spore germination
DSM104440_01680	COG0039	L-malate dehydrogenase activity
DSM104440_01686	COG1392	Phosphate transport regulator
DSM104440_01687	COG0306	phosphate transporter
DSM104440_01691	COG4106	trans-aconitate 2-methyltransferase activity
DSM104440_01692	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSM104440_01697	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DSM104440_01699	COG2079	MmgE PrpD family protein
DSM104440_01704	COG2030	dehydratase
DSM104440_01705	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104440_01708	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DSM104440_01709	COG1053	succinate dehydrogenase
DSM104440_01710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DSM104440_01711	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DSM104440_01712	COG0372	Belongs to the citrate synthase family
DSM104440_01713	COG0567	Dehydrogenase, E1 component
DSM104440_01714	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104440_01717	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104440_01718	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DSM104440_01722	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSM104440_01723	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104440_01727	COG1024	Enoyl-CoA hydratase
DSM104440_01736	COG0488	(ABC) transporter
DSM104440_01738	COG2086	electron transfer activity
DSM104440_01740	COG1960	acyl-CoA dehydrogenase activity
DSM104440_01741	COG1971	Probably functions as a manganese efflux pump
DSM104440_01746	COG2133	pyrroloquinoline quinone binding
DSM104440_01748	COG3228	Belongs to the MtfA family
DSM104440_01752	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSM104440_01753	COG1024	Enoyl-CoA hydratase
DSM104440_01754	COG1024	Enoyl-CoA hydratase
DSM104440_01759	COG4191	Histidine kinase
DSM104440_01765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104440_01771	COG4770	biotin carboxylase activity
DSM104440_01775	COG1024	Enoyl-CoA hydratase
DSM104440_01776	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104440_01778	COG1960	acyl-CoA dehydrogenase activity
DSM104440_01781	COG0183	Belongs to the thiolase family
DSM104440_01784	COG1960	acyl-CoA dehydrogenase activity
DSM104440_01787	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104440_01790	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104440_01795	COG3842	ATPase activity
DSM104440_01796	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM104440_01804	COG4555	ABC transporter
DSM104440_01806	COG1199	ATP-dependent helicase activity
DSM104440_01816	COG1214	PFAM Peptidase M22, glycoprotease
DSM104440_01818	COG1573	uracil-dna glycosylase
DSM104440_01820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DSM104440_01822	COG1414	Transcriptional regulator
DSM104440_01824	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104440_01826	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DSM104440_01830	COG4133	protoheme IX ABC transporter activity
DSM104440_01841	COG0477	Major facilitator Superfamily
DSM104440_01849	COG0745	RESPONSE REGULATOR receiver
DSM104440_01852	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSM104440_01853	COG2201	protein-glutamate methylesterase activity
DSM104440_01854	COG0835	chemotaxis
DSM104440_01855	COG2815	serine threonine protein kinase
DSM104440_01855	COG0515	serine threonine protein kinase
DSM104440_01857	COG0835	chemotaxis
DSM104440_01859	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM104440_01859	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSM104440_01860	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSM104440_01862	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DSM104440_01869	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DSM104440_01870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104440_01871	COG0726	polysaccharide deacetylase
DSM104440_01873	COG4772	TonB-dependent receptor
DSM104440_01875	COG2346	COG2346, Truncated hemoglobins
DSM104440_01881	COG1322	Protein conserved in bacteria
DSM104440_01883	COG0473	3-isopropylmalate dehydrogenase activity
DSM104440_01884	COG1763	Mo-molybdopterin cofactor biosynthetic process
DSM104440_01885	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DSM104440_01886	COG0314	molybdopterin synthase activity
DSM104440_01890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSM104440_01891	COG4654	Cytochrome c, class I
DSM104440_01896	COG2010	Cytochrome c
DSM104440_01902	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSM104440_01924	COG0640	Transcriptional regulator
DSM104440_01929	COG0587	DNA-directed DNA polymerase activity
DSM104440_01937	COG0784	Response regulator, receiver
DSM104440_01937	COG4191	Histidine kinase
DSM104440_01947	COG2985	domain, Protein
DSM104440_01948	COG2721	sulfolactate sulfo-lyase activity
DSM104440_01950	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104440_01951	COG3391	amine dehydrogenase activity
DSM104440_01954	COG2204	response regulator
DSM104440_01955	COG2204	response regulator
DSM104440_01960	COG2823	Periplasmic or secreted lipoprotein
DSM104440_01962	COG0114	fumarate hydratase activity
DSM104440_01963	COG3038	cytochrome b561
DSM104440_01964	COG2353	YceI-like domain
DSM104440_01965	COG2353	YceI-like domain
DSM104440_01968	COG0823	Involved in the tonB-independent uptake of proteins
DSM104440_01968	COG1506	peptidase
DSM104440_01973	COG0672	)-iron permease
DSM104440_01974	COG4774	siderophore transport
DSM104440_01979	COG1960	acyl-CoA dehydrogenase activity
DSM104440_01983	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104440_01984	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104440_01985	COG0277	FAD linked oxidase domain protein
DSM104440_01985	COG0247	lactate metabolic process
DSM104440_01986	COG2186	Transcriptional regulator
DSM104440_01987	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104440_01988	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104440_01997	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM104440_01998	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104440_02010	COG4221	oxidoreductase activity
DSM104440_02011	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104440_02012	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DSM104440_02014	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104440_02015	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DSM104440_02016	COG0084	hydrolase, TatD family'
DSM104440_02017	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM104440_02020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSM104440_02021	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSM104440_02022	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104440_02023	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM104440_02024	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM104440_02027	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM104440_02028	COG0416	fatty acid biosynthetic process
DSM104440_02029	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSM104440_02030	COG1399	metal-binding, possibly nucleic acid-binding protein
DSM104440_02031	COG0424	maF-like protein
DSM104440_02032	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSM104440_02036	COG0546	phosphoglycolate phosphatase activity
DSM104440_02037	COG0564	pseudouridine synthase activity
DSM104440_02038	COG1530	ribonuclease E activity
DSM104440_02041	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSM104440_02042	COG0556	nucleotide-excision repair
DSM104440_02043	COG0436	Aminotransferase
DSM104440_02044	COG3459	Glycosyltransferase 36 associated
DSM104440_02047	COG0667	Aldo Keto reductase
DSM104440_02049	COG4214	carbohydrate transport
DSM104440_02050	COG4213	ABC transporter substrate-binding protein
DSM104440_02051	COG2115	Belongs to the xylose isomerase family
DSM104440_02052	COG2115	Belongs to the xylose isomerase family
DSM104440_02053	COG1070	Carbohydrate kinase
DSM104440_02055	COG0395	ABC-type sugar transport system, permease component
DSM104440_02056	COG1175	transmembrane transport
DSM104440_02058	COG1609	Transcriptional regulator
DSM104440_02059	COG4771	TonB-dependent receptor
DSM104440_02060	COG3661	Belongs to the glycosyl hydrolase 67 family
DSM104440_02061	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104440_02062	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104440_02064	COG0840	transmembrane signaling receptor activity
DSM104440_02068	COG3507	Belongs to the glycosyl hydrolase 43 family
DSM104440_02073	COG1566	PFAM secretion protein HlyD family protein
DSM104440_02079	COG1187	pseudouridine synthase activity
DSM104440_02081	COG2264	protein methyltransferase activity
DSM104440_02084	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104440_02086	COG3195	allantoin biosynthetic process
DSM104440_02086	COG3648	Uricase
DSM104440_02090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM104440_02093	COG0402	S-adenosylhomocysteine deaminase activity
DSM104440_02094	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DSM104440_02095	COG1744	ABC transporter substrate-binding protein PnrA-like
DSM104440_02096	COG1609	Transcriptional regulator
DSM104440_02097	COG3845	ABC transporter
DSM104440_02098	COG4603	Belongs to the binding-protein-dependent transport system permease family
DSM104440_02099	COG1079	Belongs to the binding-protein-dependent transport system permease family
DSM104440_02103	COG1012	belongs to the aldehyde dehydrogenase family
DSM104440_02106	COG0737	Belongs to the 5'-nucleotidase family
DSM104440_02106	COG1525	nuclease
DSM104440_02106	COG4085	toxin activity
DSM104440_02107	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM104440_02109	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DSM104440_02116	COG0322	excinuclease ABC activity
DSM104440_02117	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104440_02118	COG0736	holo-[acyl-carrier-protein] synthase activity
DSM104440_02119	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSM104440_02120	COG1381	Involved in DNA repair and RecF pathway recombination
DSM104440_02121	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSM104440_02122	COG0571	ribonuclease III activity
DSM104440_02124	COG0681	Belongs to the peptidase S26 family
DSM104440_02125	COG0481	GTPase activity
DSM104440_02127	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104440_02131	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSM104440_02132	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSM104440_02132	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSM104440_02134	COG0516	GMP reductase activity
DSM104440_02134	COG0517	IMP dehydrogenase activity
DSM104440_02135	COG1136	(ABC) transporter
DSM104440_02136	COG0577	efflux transmembrane transporter activity
DSM104440_02138	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DSM104440_02138	COG2755	lipolytic protein G-D-S-L family
DSM104440_02139	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104440_02142	COG1024	Enoyl-CoA hydratase
DSM104440_02143	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104440_02148	COG5001	Diguanylate cyclase
DSM104440_02148	COG3300	MHYT domain
DSM104440_02149	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104440_02152	COG2050	protein possibly involved in aromatic compounds catabolism
DSM104440_02155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSM104440_02156	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DSM104440_02159	COG0243	molybdopterin cofactor binding
DSM104440_02162	COG0006	proline dipeptidase activity
DSM104440_02163	COG1802	Transcriptional regulator
DSM104440_02164	COG3938	Belongs to the proline racemase family
DSM104440_02165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104440_02168	COG1506	peptidase
DSM104440_02168	COG0823	Involved in the tonB-independent uptake of proteins
DSM104440_02170	COG1917	Cupin 2, conserved barrel domain protein
DSM104440_02170	COG2169	Transcriptional regulator
DSM104440_02171	COG0346	lactoylglutathione lyase activity
DSM104440_02173	COG0596	Alpha beta hydrolase
DSM104440_02184	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104440_02187	COG0300	oxidoreductase activity
DSM104440_02192	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DSM104440_02196	COG0732	type I restriction modification DNA specificity domain
DSM104440_02197	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DSM104440_02199	COG0542	response to heat
DSM104440_02200	COG1215	transferase activity, transferring glycosyl groups
DSM104440_02207	COG0436	Aminotransferase
DSM104440_02209	COG0484	heat shock protein binding
DSM104440_02210	COG0484	heat shock protein binding
DSM104440_02211	COG2902	Dehydrogenase
DSM104440_02212	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104440_02213	COG0765	amino acid transport
DSM104440_02214	COG0765	amino acid transport
DSM104440_02215	COG1126	abc transporter atp-binding protein
DSM104440_02219	COG0714	Associated with various cellular activities
DSM104440_02224	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104440_02225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DSM104440_02226	COG3590	peptidase
DSM104440_02227	COG3964	amidohydrolase
DSM104440_02229	COG0509	glycine decarboxylation via glycine cleavage system
DSM104440_02230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSM104440_02231	COG0156	8-amino-7-oxononanoate synthase activity
DSM104440_02232	COG1063	alcohol dehydrogenase
DSM104440_02236	COG3842	ATPase activity
DSM104440_02239	COG0546	phosphoglycolate phosphatase activity
DSM104440_02243	COG0776	regulation of translation
DSM104440_02244	COG0072	phenylalanine-tRNA ligase activity
DSM104440_02244	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104440_02245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSM104440_02246	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSM104440_02247	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSM104440_02248	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DSM104440_02249	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSM104440_02250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DSM104440_02251	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSM104440_02257	COG0829	nickel cation binding
DSM104440_02258	COG0831	urea catabolic process
DSM104440_02259	COG0832	Belongs to the urease beta subunit family
DSM104440_02260	COG0804	urea catabolic process
DSM104440_02261	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DSM104440_02262	COG0830	nickel cation binding
DSM104440_02263	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DSM104440_02269	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM104440_02271	COG2308	Evidence 4 Homologs of previously reported genes of
DSM104440_02279	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DSM104440_02287	COG1136	(ABC) transporter
DSM104440_02290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSM104440_02292	COG4771	TonB-dependent receptor
DSM104440_02293	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DSM104440_02295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSM104440_02297	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM104440_02298	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DSM104440_02300	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_02301	COG1505	serine-type exopeptidase activity
DSM104440_02302	COG2197	response regulator
DSM104440_02303	COG4585	Histidine kinase
DSM104440_02306	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_02307	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSM104440_02310	COG0564	pseudouridine synthase activity
DSM104440_02312	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DSM104440_02313	COG0248	Ppx GppA phosphatase
DSM104440_02314	COG2062	phosphohistidine phosphatase, SixA
DSM104440_02317	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DSM104440_02318	COG4181	ATPase activity
DSM104440_02320	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DSM104440_02321	COG2815	serine threonine protein kinase
DSM104440_02321	COG0515	serine threonine protein kinase
DSM104440_02322	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DSM104440_02323	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSM104440_02324	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSM104440_02325	COG0406	alpha-ribazole phosphatase activity
DSM104440_02326	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSM104440_02327	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSM104440_02330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104440_02331	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM104440_02332	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104440_02333	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DSM104440_02334	COG1674	ftsk spoiiie
DSM104440_02336	COG0492	ferredoxin-NADP+ reductase activity
DSM104440_02338	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSM104440_02339	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DSM104440_02349	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104440_02351	COG1024	Enoyl-CoA hydratase
DSM104440_02352	COG1596	polysaccharide export
DSM104440_02352	COG1555	photosystem II stabilization
DSM104440_02354	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104440_02355	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DSM104440_02357	COG0284	orotidine-5'-phosphate decarboxylase activity
DSM104440_02358	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DSM104440_02363	COG0776	regulation of translation
DSM104440_02365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSM104440_02366	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSM104440_02367	COG0287	Prephenate dehydrogenase
DSM104440_02368	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM104440_02370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104440_02371	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSM104440_02374	COG0402	S-adenosylhomocysteine deaminase activity
DSM104440_02375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104440_02380	COG0438	transferase activity, transferring glycosyl groups
DSM104440_02380	COG1216	Glycosyl transferase, family 2
DSM104440_02383	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104440_02385	COG3629	intracellular signal transduction
DSM104440_02385	COG3903	Transcriptional regulator
DSM104440_02389	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104440_02392	COG2032	superoxide dismutase activity
DSM104440_02394	COG2864	formate dehydrogenase
DSM104440_02396	COG0437	4 iron, 4 sulfur cluster binding
DSM104440_02397	COG0243	molybdopterin cofactor binding
DSM104440_02397	COG3383	formate dehydrogenase (NAD+) activity
DSM104440_02403	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSM104440_02404	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSM104440_02406	COG0746	molybdenum cofactor guanylyltransferase activity
DSM104440_02410	COG1309	transcriptional regulator
DSM104440_02415	COG0583	DNA-binding transcription factor activity
DSM104440_02416	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSM104440_02418	COG0175	sulfate reduction
DSM104440_02419	COG0175	sulfate reduction
DSM104440_02420	COG2895	sulfate adenylyltransferase (ATP) activity
DSM104440_02422	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DSM104440_02424	COG4208	sulfate ABC transporter
DSM104440_02425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSM104440_02430	COG4654	Cytochrome c, class I
DSM104440_02431	COG3005	denitrification pathway
DSM104440_02436	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSM104440_02438	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DSM104440_02439	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DSM104440_02440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DSM104440_02441	COG0167	dihydroorotate dehydrogenase activity
DSM104440_02442	COG0686	Belongs to the AlaDH PNT family
DSM104440_02443	COG2878	Part of a membrane complex involved in electron transport
DSM104440_02444	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSM104440_02450	COG1595	DNA-templated transcription, initiation
DSM104440_02451	COG5002	protein histidine kinase activity
DSM104440_02451	COG5001	Diguanylate cyclase
DSM104440_02452	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DSM104440_02453	COG0328	RNA-DNA hybrid ribonuclease activity
DSM104440_02455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104440_02461	COG0741	lytic transglycosylase activity
DSM104440_02461	COG1388	LysM domain
DSM104440_02462	COG0339	signal peptide processing
DSM104440_02465	COG0601	transmembrane transport
DSM104440_02466	COG0747	negative chemotaxis
DSM104440_02467	COG4166	transmembrane transport
DSM104440_02470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104440_02473	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSM104440_02474	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSM104440_02475	COG0740	serine-type endopeptidase activity
DSM104440_02476	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSM104440_02479	COG1562	ergosterol biosynthetic process
DSM104440_02480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DSM104440_02481	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_02484	COG0515	serine threonine protein kinase
DSM104440_02484	COG2815	serine threonine protein kinase
DSM104440_02486	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSM104440_02488	COG0359	binds to the 23S rRNA
DSM104440_02489	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSM104440_02491	COG0360	Binds together with S18 to 16S ribosomal RNA
DSM104440_02502	COG0297	glycogen (starch) synthase activity
DSM104440_02503	COG1091	dTDP-4-dehydrorhamnose reductase activity
DSM104440_02506	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104440_02513	COG0612	Peptidase, M16
DSM104440_02514	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104440_02515	COG0557	exoribonuclease II activity
DSM104440_02518	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSM104440_02519	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DSM104440_02521	COG0330	HflC and HflK could
DSM104440_02522	COG0330	HflC and HflK could
DSM104440_02523	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSM104440_02524	COG1923	regulation of RNA biosynthetic process
DSM104440_02525	COG1160	GTP binding
DSM104440_02527	COG2976	Protein conserved in bacteria
DSM104440_02528	COG0124	histidyl-tRNA synthetase
DSM104440_02529	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSM104440_02532	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSM104440_02533	COG0105	UTP biosynthetic process
DSM104440_02534	COG0037	tRNA processing
DSM104440_02535	COG0825	malonyl-CoA metabolic process
DSM104440_02536	COG2096	Adenosyltransferase
DSM104440_02540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSM104440_02541	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSM104440_02542	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSM104440_02543	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSM104440_02547	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM104440_02551	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM104440_02558	COG0312	modulator of DNA gyrase
DSM104440_02561	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSM104440_02576	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DSM104440_02576	COG1073	alpha beta
DSM104440_02576	COG3064	Membrane
DSM104440_02595	COG0429	hydrolase of the alpha beta-hydrolase fold
DSM104440_02607	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_02610	COG0625	glutathione transferase activity
DSM104440_02615	COG0625	glutathione transferase activity
DSM104440_02622	COG2217	Heavy metal translocating P-type atpase
DSM104440_02623	COG1505	serine-type exopeptidase activity
DSM104440_02624	COG1132	(ABC) transporter
DSM104440_02630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DSM104440_02634	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104440_02635	COG3647	Membrane
DSM104440_02636	COG1940	carbohydrate kinase activity
DSM104440_02640	COG0438	transferase activity, transferring glycosyl groups
DSM104440_02644	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSM104440_02645	COG3540	Alkaline phosphatase
DSM104440_02648	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_02656	COG3158	transport of potassium into the cell
DSM104440_02660	COG2135	peptidase activity
DSM104440_02662	COG0322	excinuclease ABC activity
DSM104440_02663	COG0583	DNA-binding transcription factor activity
DSM104440_02668	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104440_02668	COG4651	solute:proton antiporter activity
DSM104440_02669	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSM104440_02674	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_02676	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104440_02680	COG1278	Cold shock
DSM104440_02684	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104440_02687	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM104440_02688	COG2755	lipolytic protein G-D-S-L family
DSM104440_02696	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DSM104440_02697	COG0583	DNA-binding transcription factor activity
DSM104440_02698	COG1678	Uncharacterized ACR, COG1678
DSM104440_02699	COG2972	Histidine kinase
DSM104440_02702	COG1733	regulation of RNA biosynthetic process
DSM104440_02704	COG2124	cytochrome p450
DSM104440_02704	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DSM104440_02707	COG0457	Tetratricopeptide repeat
DSM104440_02707	COG3710	Transcriptional regulator
DSM104440_02709	COG0431	NADPH-dependent FMN reductase
DSM104440_02716	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104440_02717	COG0765	amino acid transport
DSM104440_02718	COG0765	amino acid transport
DSM104440_02721	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104440_02724	COG0513	Belongs to the DEAD box helicase family
DSM104440_02726	COG0534	Mate efflux family protein
DSM104440_02728	COG0222	ribosome binding
DSM104440_02734	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104440_02736	COG1690	Belongs to the RtcB family
DSM104440_02738	COG3795	YCII-related domain
DSM104440_02741	COG1309	transcriptional regulator
DSM104440_02745	COG0625	glutathione transferase activity
DSM104440_02746	COG0165	Argininosuccinate lyase
DSM104440_02748	COG0583	DNA-binding transcription factor activity
DSM104440_02757	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM104440_02757	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM104440_02766	COG1538	Outer membrane efflux protein
DSM104440_02768	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_02773	COG2205	protein histidine kinase activity
DSM104440_02774	COG0745	RESPONSE REGULATOR receiver
DSM104440_02777	COG0142	geranyltranstransferase activity
DSM104440_02778	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSM104440_02779	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSM104440_02780	COG1280	lysine exporter protein (LysE YggA)
DSM104440_02781	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSM104440_02787	COG0494	nUDIX hydrolase
DSM104440_02788	COG0442	prolyl-tRNA aminoacylation
DSM104440_02789	COG0741	lytic transglycosylase activity
DSM104440_02791	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104440_02793	COG1959	2 iron, 2 sulfur cluster binding
DSM104440_02793	COG1295	ribonuclease BN
DSM104440_02796	COG0586	Pfam SNARE associated Golgi protein
DSM104440_02797	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104440_02798	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104440_02799	COG1862	Preprotein translocase
DSM104440_02800	COG0343	queuine tRNA-ribosyltransferase activity
DSM104440_02802	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSM104440_02803	COG0205	6-phosphofructokinase activity
DSM104440_02804	COG0563	adenylate kinase activity
DSM104440_02805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DSM104440_02806	COG2835	tetraacyldisaccharide 4'-kinase activity
DSM104440_02807	COG1663	tetraacyldisaccharide 4'-kinase activity
DSM104440_02810	COG1570	exodeoxyribonuclease VII activity
DSM104440_02811	COG3360	Dodecin
DSM104440_02812	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSM104440_02813	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSM104440_02815	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM104440_02816	COG0802	atpase or kinase
DSM104440_02817	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSM104440_02823	COG0277	FAD linked oxidase domain protein
DSM104440_02826	COG3735	TraB family
DSM104440_02828	COG2095	MarC family integral membrane protein
DSM104440_02829	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104440_02831	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DSM104440_02832	COG0148	phosphopyruvate hydratase activity
DSM104440_02839	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104440_02848	COG3201	nicotinamide mononucleotide transporter
DSM104440_02856	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DSM104440_02859	COG0004	ammonium transporteR
DSM104440_02862	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DSM104440_02863	COG0504	CTP synthase activity
DSM104440_02866	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSM104440_02867	COG0235	Class ii aldolase
DSM104440_02871	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSM104440_02878	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104440_02881	COG0251	oxidation-reduction process
DSM104440_02883	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM104440_02884	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104440_02887	COG0166	Belongs to the GPI family
DSM104440_02897	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSM104440_02899	COG1007	ATP synthesis coupled electron transport
DSM104440_02902	COG0713	ATP synthesis coupled electron transport
DSM104440_02903	COG0839	Belongs to the complex I subunit 6 family
DSM104440_02904	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_02905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSM104440_02906	COG1034	ATP synthesis coupled electron transport
DSM104440_02907	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSM104440_02910	COG0649	NAD binding
DSM104440_02911	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_02912	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_02913	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104440_02916	COG0149	triose-phosphate isomerase activity
DSM104440_02920	COG0798	PFAM Bile acid sodium symporter
DSM104440_02922	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSM104440_02923	COG0581	inorganic phosphate transmembrane transporter activity
DSM104440_02924	COG0573	inorganic phosphate transmembrane transporter activity
DSM104440_02925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSM104440_02926	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM104440_02927	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSM104440_02928	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104440_02929	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSM104440_02931	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM104440_02932	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM104440_02933	COG0505	Belongs to the CarA family
DSM104440_02934	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DSM104440_02935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSM104440_02936	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104440_02937	COG0735	belongs to the Fur family
DSM104440_02940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DSM104440_02940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DSM104440_02940	COG0506	proline dehydrogenase activity
DSM104440_02941	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104440_02942	COG0783	Belongs to the Dps family
DSM104440_02946	COG1741	Belongs to the pirin family
DSM104440_02947	COG0583	DNA-binding transcription factor activity
DSM104440_02948	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104440_02958	COG0515	serine threonine protein kinase
DSM104440_02963	COG0473	3-isopropylmalate dehydrogenase activity
DSM104440_02964	COG0596	Alpha beta hydrolase
DSM104440_02967	COG0515	serine threonine protein kinase
DSM104440_02969	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DSM104440_02975	COG1881	PFAM PEBP family protein
DSM104440_02976	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSM104440_02977	COG0405	Gamma-glutamyltransferase
DSM104440_02981	COG5001	Diguanylate cyclase
DSM104440_02981	COG3300	MHYT domain
DSM104440_02983	COG0747	negative chemotaxis
DSM104440_02989	COG1733	regulation of RNA biosynthetic process
DSM104440_02990	COG3186	Phenylalanine-4-hydroxylase
DSM104440_02992	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DSM104440_02997	COG0747	negative chemotaxis
DSM104440_02998	COG4166	transmembrane transport
DSM104440_02999	COG0601	transmembrane transport
DSM104440_03000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104440_03003	COG0444	Belongs to the ABC transporter superfamily
DSM104440_03004	COG4608	Belongs to the ABC transporter superfamily
DSM104440_03007	COG1696	Membrane protein involved in D-alanine export
DSM104440_03010	COG0436	Aminotransferase
DSM104440_03011	COG1643	Atp-dependent helicase
DSM104440_03017	COG0625	glutathione transferase activity
DSM104440_03018	COG2084	Dehydrogenase
DSM104440_03020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSM104440_03022	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104440_03024	COG1556	Lactate utilization protein
DSM104440_03026	COG0247	lactate metabolic process
DSM104440_03027	COG1196	nuclear chromosome segregation
DSM104440_03027	COG0741	lytic transglycosylase activity
DSM104440_03027	COG0739	heme binding
DSM104440_03028	COG1686	Belongs to the peptidase S11 family
DSM104440_03031	COG5265	(ABC) transporter
DSM104440_03032	COG0662	Cupin 2, conserved barrel domain protein
DSM104440_03039	COG4771	TonB-dependent receptor
DSM104440_03042	COG3622	Belongs to the hyi family
DSM104440_03043	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104440_03051	COG3383	formate dehydrogenase (NAD+) activity
DSM104440_03053	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DSM104440_03055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSM104440_03056	COG0045	succinate-CoA ligase (ADP-forming) activity
DSM104440_03058	COG0515	serine threonine protein kinase
DSM104440_03058	COG2815	serine threonine protein kinase
DSM104440_03062	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104440_03063	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104440_03070	COG0861	Integral membrane protein TerC family
DSM104440_03073	COG0617	tRNA 3'-terminal CCA addition
DSM104440_03076	COG2358	TRAP transporter, solute receptor (TAXI family
DSM104440_03077	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DSM104440_03078	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DSM104440_03090	COG0037	tRNA processing
DSM104440_03093	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104440_03100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSM104440_03102	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSM104440_03103	COG0625	glutathione transferase activity
DSM104440_03114	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSM104440_03118	COG1560	Kdo2-lipid A biosynthetic process
DSM104440_03119	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSM104440_03121	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DSM104440_03122	COG0523	cobalamin synthesis protein
DSM104440_03123	COG0523	cobalamin synthesis protein
DSM104440_03125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DSM104440_03126	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DSM104440_03130	COG3220	belongs to the UPF0276 family
DSM104440_03133	COG0071	Belongs to the small heat shock protein (HSP20) family
DSM104440_03134	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSM104440_03136	COG3568	Endonuclease Exonuclease Phosphatase
DSM104440_03137	COG0494	nUDIX hydrolase
DSM104440_03138	COG1446	asparaginase
DSM104440_03139	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSM104440_03142	COG0501	Belongs to the peptidase M48B family
DSM104440_03143	COG0629	single-stranded DNA binding
DSM104440_03144	COG2814	Major facilitator Superfamily
DSM104440_03147	COG0203	ribosomal protein L17
DSM104440_03148	COG0202	RNA polymerase activity
DSM104440_03149	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSM104440_03150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSM104440_03151	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSM104440_03152	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSM104440_03153	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSM104440_03154	COG0201	protein transport
DSM104440_03155	COG0200	Binds to the 23S rRNA
DSM104440_03156	COG1841	ribosomal large subunit assembly
DSM104440_03157	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSM104440_03158	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSM104440_03159	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSM104440_03162	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSM104440_03163	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSM104440_03164	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSM104440_03165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSM104440_03166	COG0255	Belongs to the universal ribosomal protein uL29 family
DSM104440_03167	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DSM104440_03168	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSM104440_03169	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSM104440_03170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSM104440_03171	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSM104440_03172	COG0089	rRNA binding
DSM104440_03173	COG0088	Forms part of the polypeptide exit tunnel
DSM104440_03174	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSM104440_03175	COG0051	transcription antitermination factor activity, RNA binding
DSM104440_03177	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM104440_03178	COG0049	tRNA binding
DSM104440_03179	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSM104440_03180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSM104440_03181	COG0085	RNA polymerase activity
DSM104440_03182	COG0222	ribosome binding
DSM104440_03183	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSM104440_03184	COG0081	regulation of translation
DSM104440_03185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSM104440_03187	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSM104440_03194	COG2969	positive regulation of protein catabolic process
DSM104440_03195	COG0625	glutathione transferase activity
DSM104440_03196	COG2857	Cytochrome c1
DSM104440_03197	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSM104440_03198	COG0723	plastoquinol--plastocyanin reductase activity
DSM104440_03199	COG1970	mechanosensitive ion channel activity
DSM104440_03201	COG0805	protein transport
DSM104440_03202	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104440_03203	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104440_03205	COG0140	phosphoribosyl-ATP diphosphatase activity
DSM104440_03206	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSM104440_03208	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSM104440_03209	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSM104440_03210	COG0131	Imidazoleglycerol-phosphate dehydratase
DSM104440_03211	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM104440_03212	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSM104440_03213	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSM104440_03214	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSM104440_03215	COG0271	Belongs to the BolA IbaG family
DSM104440_03216	COG0842	Transport permease protein
DSM104440_03217	COG1131	(ABC) transporter
DSM104440_03219	COG2854	intermembrane phospholipid transfer
DSM104440_03220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSM104440_03221	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSM104440_03222	COG1127	ABC transporter
DSM104440_03224	COG3409	Peptidoglycan-binding domain 1 protein
DSM104440_03224	COG3267	Type II secretory pathway component ExeA
DSM104440_03227	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104440_03234	COG1469	GTP cyclohydrolase I activity
DSM104440_03236	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSM104440_03239	COG0137	argininosuccinate synthase activity
DSM104440_03240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSM104440_03241	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM104440_03242	COG0268	Binds directly to 16S ribosomal RNA
DSM104440_03243	COG0728	peptidoglycan biosynthetic process
DSM104440_03244	COG0196	riboflavin kinase activity
DSM104440_03245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSM104440_03246	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSM104440_03247	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSM104440_03256	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM104440_03257	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DSM104440_03260	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DSM104440_03261	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSM104440_03261	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DSM104440_03262	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSM104440_03263	COG3766	membrane
DSM104440_03264	COG0754	glutathionylspermidine amidase activity
DSM104440_03266	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSM104440_03267	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DSM104440_03268	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSM104440_03270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSM104440_03273	COG0126	phosphoglycerate kinase activity
DSM104440_03274	COG0469	pyruvate kinase activity
DSM104440_03277	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSM104440_03280	COG0730	response to heat
DSM104440_03284	COG4206	TonB-dependent receptor
DSM104440_03285	COG3510	cephalosporin hydroxylase
DSM104440_03290	COG0859	PFAM glycosyl transferase family 9
DSM104440_03291	COG0438	transferase activity, transferring glycosyl groups
DSM104440_03292	COG1132	(ABC) transporter
DSM104440_03293	COG0438	transferase activity, transferring glycosyl groups
DSM104440_03294	COG0859	PFAM glycosyl transferase family 9
DSM104440_03303	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104440_03306	COG1450	Type ii and iii secretion system protein
DSM104440_03309	COG3166	PFAM Fimbrial assembly family protein
DSM104440_03310	COG3156	type II secretion system protein K
DSM104440_03312	COG2165	general secretion pathway protein
DSM104440_03313	COG4970	Tfp pilus assembly protein FimT
DSM104440_03314	COG2165	general secretion pathway protein
DSM104440_03315	COG1459	type II secretion system
DSM104440_03316	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104440_03317	COG0662	Cupin 2, conserved barrel domain protein
DSM104440_03317	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DSM104440_03319	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104440_03325	COG2264	protein methyltransferase activity
DSM104440_03326	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104440_03329	COG1215	transferase activity, transferring glycosyl groups
DSM104440_03330	COG0463	Glycosyl transferase, family 2
DSM104440_03331	COG0367	asparagine synthase
DSM104440_03333	COG2226	methyltransferase
DSM104440_03341	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSM104440_03344	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_03349	COG0463	Glycosyl transferase, family 2
DSM104440_03366	COG0438	transferase activity, transferring glycosyl groups
DSM104440_03366	COG1216	Glycosyl transferase, family 2
DSM104440_03369	COG0438	transferase activity, transferring glycosyl groups
DSM104440_03371	COG0004	ammonium transporteR
DSM104440_03372	COG0347	Belongs to the P(II) protein family
DSM104440_03376	COG0606	chelatase, subunit chli
DSM104440_03377	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DSM104440_03380	COG2814	Major facilitator Superfamily
DSM104440_03381	COG2814	Major facilitator Superfamily
DSM104440_03383	COG1473	amidohydrolase
DSM104440_03386	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104440_03389	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_03390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104440_03397	COG0625	glutathione transferase activity
DSM104440_03400	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_03403	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSM104440_03404	COG0142	geranyltranstransferase activity
DSM104440_03405	COG1722	exodeoxyribonuclease VII activity
DSM104440_03414	COG1450	Type ii and iii secretion system protein
DSM104440_03425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104440_03430	COG1649	PFAM Uncharacterised BCR, COG1649
DSM104440_03436	COG0745	RESPONSE REGULATOR receiver
DSM104440_03440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSM104440_03443	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104440_03444	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104440_03445	COG1053	succinate dehydrogenase
DSM104440_03458	COG2855	membrane
DSM104440_03459	COG2721	sulfolactate sulfo-lyase activity
DSM104440_03461	COG1609	Transcriptional regulator
DSM104440_03463	COG2321	neutral zinc metallopeptidase
DSM104440_03464	COG0335	large ribosomal subunit rRNA binding
DSM104440_03465	COG0336	Belongs to the RNA methyltransferase TrmD family
DSM104440_03466	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSM104440_03467	COG0228	four-way junction DNA binding
DSM104440_03468	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104440_03470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSM104440_03472	COG4536	flavin adenine dinucleotide binding
DSM104440_03478	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104440_03479	COG0288	reversible hydration of carbon dioxide
DSM104440_03482	COG3483	tryptophan 2,3-dioxygenase activity
DSM104440_03488	COG2208	phosphoserine phosphatase activity
DSM104440_03489	COG1234	tRNA 3'-trailer cleavage
DSM104440_03490	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM104440_03491	COG0745	RESPONSE REGULATOR receiver
DSM104440_03492	COG2205	protein histidine kinase activity
DSM104440_03496	COG1609	Transcriptional regulator
DSM104440_03499	COG3386	PFAM SMP-30 Gluconolaconase
DSM104440_03500	COG3836	Belongs to the HpcH HpaI aldolase family
DSM104440_03502	COG0842	Transport permease protein
DSM104440_03503	COG1131	(ABC) transporter
DSM104440_03505	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSM104440_03509	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104440_03510	COG2081	HI0933 family
DSM104440_03511	COG0667	Aldo Keto reductase
DSM104440_03512	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DSM104440_03517	COG0789	Transcriptional regulator
DSM104440_03522	COG1131	(ABC) transporter
DSM104440_03527	COG2312	Erythromycin esterase
DSM104440_03543	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_03553	COG0459	protein refolding
DSM104440_03554	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSM104440_03561	COG2823	Periplasmic or secreted lipoprotein
DSM104440_03567	COG0564	pseudouridine synthase activity
DSM104440_03570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DSM104440_03572	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DSM104440_03573	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM104440_03574	COG2188	Transcriptional regulator
DSM104440_03576	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DSM104440_03577	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM104440_03577	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104440_03578	COG1263	PTS System
DSM104440_03578	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM104440_03578	COG2190	(PTS) system
DSM104440_03579	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM104440_03583	COG2027	D-alanyl-D-alanine carboxypeptidase
DSM104440_03588	COG4941	Belongs to the sigma-70 factor family
DSM104440_03589	COG3795	YCII-related domain
DSM104440_03592	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DSM104440_03600	COG1960	acyl-CoA dehydrogenase activity
DSM104440_03602	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DSM104440_03605	COG1981	membrane
DSM104440_03606	COG4232	protein-disulfide reductase activity
DSM104440_03613	COG2945	thiolester hydrolase activity
DSM104440_03618	COG2972	Histidine kinase
DSM104440_03628	COG3842	ATPase activity
DSM104440_03630	COG1175	transmembrane transport
DSM104440_03631	COG0395	ABC-type sugar transport system, permease component
DSM104440_03635	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104440_03636	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSM104440_03639	COG0515	serine threonine protein kinase
DSM104440_03641	COG2814	Major facilitator Superfamily
DSM104440_03644	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104440_03645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104440_03652	COG2226	methyltransferase
DSM104440_03657	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104440_03658	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM104440_03660	COG3064	Membrane
DSM104440_03661	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104440_03662	COG2813	Specifically methylates the guanine in position
DSM104440_03662	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104440_03664	COG2223	nitrite transmembrane transporter activity
DSM104440_03665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104440_03667	COG0488	(ABC) transporter
DSM104440_03668	COG0708	Exodeoxyribonuclease III
DSM104440_03669	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSM104440_03671	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104440_03672	COG0154	amidase activity
DSM104440_03673	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104440_03674	COG1077	Cell shape determining protein MreB Mrl
DSM104440_03675	COG1792	Involved in formation and maintenance of cell shape
DSM104440_03676	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DSM104440_03677	COG0768	penicillin binding
DSM104440_03678	COG0772	Belongs to the SEDS family
DSM104440_03680	COG1686	Belongs to the peptidase S11 family
DSM104440_03681	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104440_03682	COG2921	Belongs to the UPF0250 family
DSM104440_03683	COG0321	lipoyl(octanoyl) transferase activity
DSM104440_03688	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSM104440_03690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104440_03694	COG3275	phosphorelay sensor kinase activity
DSM104440_03695	COG0165	Argininosuccinate lyase
DSM104440_03701	COG2239	Acts as a magnesium transporter
DSM104440_03702	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSM104440_03703	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSM104440_03704	COG0174	glutamine synthetase
DSM104440_03706	COG3852	Histidine kinase
DSM104440_03707	COG2204	response regulator
DSM104440_03711	COG0339	signal peptide processing
DSM104440_03713	COG0540	Belongs to the ATCase OTCase family
DSM104440_03715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DSM104440_03716	COG1678	Uncharacterized ACR, COG1678
DSM104440_03721	COG3150	esterase
DSM104440_03723	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104440_03726	COG0189	ligase activity
DSM104440_03730	COG1238	metal cluster binding
DSM104440_03731	COG0181	hydroxymethylbilane synthase activity
DSM104440_03732	COG1587	Uroporphyrinogen-III synthase
DSM104440_03739	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104440_03740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSM104440_03741	COG0511	ligase activity, forming carbon-carbon bonds
DSM104440_03742	COG0439	Biotin carboxylase
DSM104440_03743	COG2264	protein methyltransferase activity
DSM104440_03746	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104440_03750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DSM104440_03751	COG3245	cytochrome
DSM104440_03755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104440_03759	COG0070	glutamate synthase
DSM104440_03759	COG0069	glutamate synthase activity
DSM104440_03759	COG0067	glutamate synthase
DSM104440_03763	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSM104440_03765	COG0018	arginyl-trna synthetase
DSM104440_03767	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSM104440_03768	COG0300	oxidoreductase activity
DSM104440_03769	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104440_03771	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104440_03773	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104440_03776	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104440_03777	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104440_03780	COG2271	Major facilitator Superfamily
DSM104440_03786	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM104440_03787	COG2323	membrane
DSM104440_03788	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM104440_03792	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104440_03793	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104440_03794	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSM104440_03795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSM104440_03799	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM104440_03800	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSM104440_03802	COG0356	it plays a direct role in the translocation of protons across the membrane
DSM104440_03804	COG1475	DNA binding
DSM104440_03805	COG1192	Involved in chromosome partitioning
DSM104440_03806	COG0357	Ribosomal RNA small subunit methyltransferase G
DSM104440_03807	COG0445	tRNA wobble uridine modification
DSM104440_03810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSM104440_03811	COG0706	membrane insertase activity
DSM104440_03812	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSM104440_03813	COG0594	ribonuclease P activity
DSM104440_03814	COG0230	Belongs to the bacterial ribosomal protein bL34 family