locus-tag	class	description
DSM104443_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DSM104443_00002	COG0592	DNA-directed DNA polymerase activity
DSM104443_00008	COG0758	DNA mediated transformation
DSM104443_00010	COG0242	peptide deformylase activity
DSM104443_00011	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104443_00013	COG5000	phosphorelay sensor kinase activity
DSM104443_00014	COG2204	response regulator
DSM104443_00017	COG4608	Belongs to the ABC transporter superfamily
DSM104443_00018	COG0444	Belongs to the ABC transporter superfamily
DSM104443_00019	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_00020	COG0601	transmembrane transport
DSM104443_00021	COG0747	negative chemotaxis
DSM104443_00023	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSM104443_00033	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSM104443_00036	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSM104443_00037	COG0352	thiamine-phosphate diphosphorylase activity
DSM104443_00038	COG0351	phosphomethylpyrimidine kinase
DSM104443_00039	COG1773	rubredoxin
DSM104443_00043	COG0840	transmembrane signaling receptor activity
DSM104443_00044	COG0643	Histidine kinase
DSM104443_00044	COG2198	Histidine kinase
DSM104443_00044	COG0784	Response regulator, receiver
DSM104443_00047	COG1968	undecaprenyl-diphosphatase activity
DSM104443_00050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSM104443_00053	COG1131	(ABC) transporter
DSM104443_00054	COG0842	Transport permease protein
DSM104443_00055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104443_00056	COG1538	Outer membrane efflux protein
DSM104443_00068	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DSM104443_00070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DSM104443_00071	COG1137	ATPase activity
DSM104443_00072	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DSM104443_00073	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSM104443_00075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DSM104443_00076	COG1660	Displays ATPase and GTPase activities
DSM104443_00080	COG3275	phosphorelay sensor kinase activity
DSM104443_00081	COG3279	Response regulator of the LytR AlgR family
DSM104443_00083	COG2022	thiamine diphosphate biosynthetic process
DSM104443_00085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSM104443_00087	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM104443_00088	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DSM104443_00089	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSM104443_00090	COG0631	protein serine/threonine phosphatase activity
DSM104443_00091	COG2815	serine threonine protein kinase
DSM104443_00091	COG0515	serine threonine protein kinase
DSM104443_00092	COG1561	YicC-like family, N-terminal region
DSM104443_00093	COG0194	GDP metabolic process
DSM104443_00094	COG1758	RNA polymerase activity
DSM104443_00095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM104443_00097	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSM104443_00098	COG3161	chorismate lyase activity
DSM104443_00100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSM104443_00102	COG0475	glutathione-regulated potassium exporter activity
DSM104443_00102	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104443_00108	COG1131	(ABC) transporter
DSM104443_00109	COG0659	secondary active sulfate transmembrane transporter activity
DSM104443_00113	COG0783	Belongs to the Dps family
DSM104443_00114	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104443_00119	COG0762	integral membrane protein
DSM104443_00122	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_00123	COG1960	acyl-CoA dehydrogenase activity
DSM104443_00126	COG0183	Belongs to the thiolase family
DSM104443_00127	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104443_00127	COG1024	Enoyl-CoA hydratase
DSM104443_00129	COG1129	ABC transporter
DSM104443_00133	COG1960	acyl-CoA dehydrogenase activity
DSM104443_00134	COG1960	acyl-CoA dehydrogenase activity
DSM104443_00136	COG2045	Belongs to the ComB family
DSM104443_00137	COG1063	alcohol dehydrogenase
DSM104443_00138	COG1414	Transcriptional regulator
DSM104443_00141	COG1530	ribonuclease E activity
DSM104443_00142	COG0424	maF-like protein
DSM104443_00143	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DSM104443_00144	COG0799	negative regulation of ribosome biogenesis
DSM104443_00145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSM104443_00146	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DSM104443_00149	COG0495	leucyl-tRNA aminoacylation
DSM104443_00151	COG0210	DNA helicase
DSM104443_00153	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSM104443_00155	COG1611	Belongs to the LOG family
DSM104443_00156	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104443_00156	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM104443_00158	COG0009	L-threonylcarbamoyladenylate synthase
DSM104443_00171	COG2815	serine threonine protein kinase
DSM104443_00171	COG0515	serine threonine protein kinase
DSM104443_00175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104443_00181	COG0138	bifunctional purine biosynthesis protein purh
DSM104443_00182	COG0151	Belongs to the GarS family
DSM104443_00185	COG0408	coproporphyrinogen oxidase activity
DSM104443_00191	COG0515	serine threonine protein kinase
DSM104443_00191	COG2815	serine threonine protein kinase
DSM104443_00200	COG4654	Cytochrome c, class I
DSM104443_00201	COG1331	Highly conserved protein containing a thioredoxin domain
DSM104443_00204	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104443_00210	COG2814	Major facilitator Superfamily
DSM104443_00214	COG0667	Aldo Keto reductase
DSM104443_00221	COG0129	dihydroxy-acid dehydratase activity
DSM104443_00223	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSM104443_00224	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104443_00233	COG2197	response regulator
DSM104443_00243	COG3237	CsbD-like
DSM104443_00244	COG0628	permease
DSM104443_00246	COG0745	RESPONSE REGULATOR receiver
DSM104443_00247	COG2205	protein histidine kinase activity
DSM104443_00251	COG0626	cystathionine gamma-synthase activity
DSM104443_00252	COG3001	Fructosamine kinase
DSM104443_00283	COG5285	phytanoyl-CoA dioxygenase
DSM104443_00307	COG1120	ATPase activity
DSM104443_00308	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM104443_00309	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSM104443_00310	COG2205	protein histidine kinase activity
DSM104443_00312	COG4771	TonB-dependent receptor
DSM104443_00313	COG1305	Transglutaminase-like
DSM104443_00315	COG0243	molybdopterin cofactor binding
DSM104443_00315	COG3383	formate dehydrogenase (NAD+) activity
DSM104443_00316	COG3383	formate dehydrogenase (NAD+) activity
DSM104443_00316	COG0243	molybdopterin cofactor binding
DSM104443_00317	COG0437	4 iron, 4 sulfur cluster binding
DSM104443_00318	COG2864	formate dehydrogenase
DSM104443_00321	COG0509	glycine decarboxylation via glycine cleavage system
DSM104443_00323	COG3276	selenocysteine insertion sequence binding
DSM104443_00328	COG1126	abc transporter atp-binding protein
DSM104443_00331	COG4149	molybdate abc transporter
DSM104443_00332	COG0725	ABC transporter, periplasmic molybdate-binding protein
DSM104443_00334	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DSM104443_00335	COG1910	domain protein
DSM104443_00338	COG3383	formate dehydrogenase (NAD+) activity
DSM104443_00339	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSM104443_00341	COG2890	protein-(glutamine-N5) methyltransferase activity
DSM104443_00342	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSM104443_00343	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DSM104443_00347	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DSM104443_00348	COG0237	dephospho-CoA kinase activity
DSM104443_00349	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DSM104443_00350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DSM104443_00353	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DSM104443_00355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DSM104443_00357	COG1845	cytochrome c oxidase, subunit III
DSM104443_00361	COG0109	protoheme IX farnesyltransferase activity
DSM104443_00362	COG1999	signal sequence binding
DSM104443_00364	COG2177	Part of the ABC transporter FtsEX involved in
DSM104443_00365	COG2884	Cell division ATP-binding protein ftsE
DSM104443_00367	COG0742	ribosomal rna small subunit methyltransferase
DSM104443_00368	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DSM104443_00369	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM104443_00371	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DSM104443_00374	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSM104443_00376	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSM104443_00377	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DSM104443_00378	COG0193	aminoacyl-tRNA hydrolase activity
DSM104443_00379	COG0012	GTP binding
DSM104443_00387	COG1702	phosphate starvation-inducible protein PhoH
DSM104443_00388	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DSM104443_00389	COG4535	Mg2 and Co2 transporter CorC
DSM104443_00390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DSM104443_00392	COG0752	glycyl-tRNA synthetase alpha subunit
DSM104443_00393	COG0751	glycine-tRNA ligase activity
DSM104443_00394	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DSM104443_00399	COG0028	Belongs to the TPP enzyme family
DSM104443_00400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSM104443_00401	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DSM104443_00402	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104443_00403	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DSM104443_00406	COG0006	proline dipeptidase activity
DSM104443_00407	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104443_00408	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104443_00411	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DSM104443_00412	COG2967	ApaG domain
DSM104443_00413	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM104443_00414	COG0546	phosphoglycolate phosphatase activity
DSM104443_00417	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DSM104443_00418	COG0134	indole-3-glycerol-phosphate synthase activity
DSM104443_00420	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DSM104443_00422	COG0628	permease
DSM104443_00423	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSM104443_00424	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSM104443_00425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DSM104443_00428	COG0316	Belongs to the HesB IscA family
DSM104443_00429	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DSM104443_00430	COG4942	peptidase
DSM104443_00431	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSM104443_00437	COG4941	Belongs to the sigma-70 factor family
DSM104443_00438	COG3795	YCII-related domain
DSM104443_00444	COG0308	aminopeptidase N
DSM104443_00445	COG0513	Belongs to the DEAD box helicase family
DSM104443_00447	COG3909	cytochrome
DSM104443_00449	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104443_00461	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM104443_00463	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DSM104443_00463	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104443_00465	COG0793	Belongs to the peptidase S41A family
DSM104443_00470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104443_00474	COG3447	MASE1 domain protein
DSM104443_00474	COG5002	protein histidine kinase activity
DSM104443_00474	COG5001	Diguanylate cyclase
DSM104443_00475	COG1127	ABC transporter
DSM104443_00477	COG1053	succinate dehydrogenase
DSM104443_00481	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104443_00484	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSM104443_00489	COG0602	queuosine metabolic process
DSM104443_00492	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM104443_00499	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSM104443_00504	COG0488	(ABC) transporter
DSM104443_00507	COG0673	inositol 2-dehydrogenase activity
DSM104443_00508	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00512	COG0129	dihydroxy-acid dehydratase activity
DSM104443_00516	COG0667	Aldo Keto reductase
DSM104443_00520	COG0515	serine threonine protein kinase
DSM104443_00522	COG1295	ribonuclease BN
DSM104443_00532	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSM104443_00533	COG2072	flavoprotein involved in K transport
DSM104443_00536	COG3275	phosphorelay sensor kinase activity
DSM104443_00537	COG2207	Transcriptional regulator
DSM104443_00550	COG1408	metallophosphoesterase
DSM104443_00557	COG1473	amidohydrolase
DSM104443_00569	COG4774	siderophore transport
DSM104443_00572	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_00577	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104443_00578	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104443_00582	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00583	COG2188	Transcriptional regulator
DSM104443_00584	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_00586	COG0745	RESPONSE REGULATOR receiver
DSM104443_00589	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSM104443_00590	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSM104443_00593	COG1278	Cold shock
DSM104443_00595	COG0745	RESPONSE REGULATOR receiver
DSM104443_00606	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104443_00614	COG0540	Belongs to the ATCase OTCase family
DSM104443_00616	COG1131	(ABC) transporter
DSM104443_00620	COG0745	RESPONSE REGULATOR receiver
DSM104443_00624	COG0584	glycerophosphoryl diester phosphodiesterase
DSM104443_00625	COG3384	dioxygenase
DSM104443_00627	COG3409	Peptidoglycan-binding domain 1 protein
DSM104443_00627	COG0793	Belongs to the peptidase S41A family
DSM104443_00631	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSM104443_00635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DSM104443_00636	COG0004	ammonium transporteR
DSM104443_00639	COG0277	FAD linked oxidase domain protein
DSM104443_00640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DSM104443_00644	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM104443_00648	COG0300	oxidoreductase activity
DSM104443_00650	COG2823	Periplasmic or secreted lipoprotein
DSM104443_00651	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSM104443_00652	COG0792	nuclease activity
DSM104443_00654	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSM104443_00655	COG0418	dihydroorotase activity
DSM104443_00659	COG1175	transmembrane transport
DSM104443_00660	COG0395	ABC-type sugar transport system, permease component
DSM104443_00661	COG4948	Mandelate Racemase Muconate Lactonizing
DSM104443_00663	COG3842	ATPase activity
DSM104443_00664	COG3734	2-keto-3-deoxy-galactonokinase
DSM104443_00665	COG0800	Aldolase
DSM104443_00668	COG2001	Belongs to the MraZ family
DSM104443_00670	COG0275	rRNA processing
DSM104443_00673	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSM104443_00674	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSM104443_00675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104443_00676	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSM104443_00677	COG0772	Belongs to the SEDS family
DSM104443_00678	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM104443_00679	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104443_00680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSM104443_00681	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM104443_00682	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DSM104443_00687	COG3064	Membrane
DSM104443_00690	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSM104443_00691	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DSM104443_00694	COG0739	heme binding
DSM104443_00695	COG0653	protein targeting
DSM104443_00696	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSM104443_00700	COG0494	nUDIX hydrolase
DSM104443_00701	COG1228	amidohydrolase
DSM104443_00702	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104443_00703	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
DSM104443_00704	COG1116	anion transmembrane transporter activity
DSM104443_00704	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_00705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104443_00706	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_00708	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DSM104443_00709	COG2226	methyltransferase
DSM104443_00710	COG2267	carboxylic ester hydrolase activity
DSM104443_00711	COG0156	8-amino-7-oxononanoate synthase activity
DSM104443_00712	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSM104443_00714	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSM104443_00715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSM104443_00717	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DSM104443_00719	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSM104443_00722	COG0588	phosphoglycerate mutase activity
DSM104443_00724	COG0793	Belongs to the peptidase S41A family
DSM104443_00725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSM104443_00728	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSM104443_00729	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSM104443_00739	COG1832	CoA-binding protein
DSM104443_00741	COG0330	HflC and HflK could
DSM104443_00744	COG0789	Transcriptional regulator
DSM104443_00748	COG1960	acyl-CoA dehydrogenase activity
DSM104443_00749	COG0183	Belongs to the thiolase family
DSM104443_00755	COG4269	membrane
DSM104443_00756	COG0501	Belongs to the peptidase M48B family
DSM104443_00757	COG1022	Amp-dependent synthetase and ligase
DSM104443_00759	COG2130	NADP-dependent
DSM104443_00762	COG1024	Enoyl-CoA hydratase
DSM104443_00762	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSM104443_00764	COG0183	Belongs to the thiolase family
DSM104443_00769	COG2363	Small membrane protein
DSM104443_00771	COG1404	Belongs to the peptidase S8 family
DSM104443_00772	COG3217	Mosc domain protein beta barrel domain protein
DSM104443_00772	COG0633	Ferredoxin
DSM104443_00773	COG4260	virion core protein, lumpy skin disease virus
DSM104443_00776	COG0678	peroxiredoxin activity
DSM104443_00777	COG1280	lysine exporter protein (LysE YggA)
DSM104443_00778	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_00779	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSM104443_00780	COG1956	GAF domain-containing protein
DSM104443_00790	COG0697	spore germination
DSM104443_00792	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DSM104443_00794	COG0515	serine threonine protein kinase
DSM104443_00794	COG2815	serine threonine protein kinase
DSM104443_00797	COG5002	protein histidine kinase activity
DSM104443_00799	COG0745	RESPONSE REGULATOR receiver
DSM104443_00800	COG0277	FAD linked oxidase domain protein
DSM104443_00801	COG0277	FAD linked oxidase domain protein
DSM104443_00802	COG0277	FAD linked oxidase domain protein
DSM104443_00803	COG0625	glutathione transferase activity
DSM104443_00804	COG0247	lactate metabolic process
DSM104443_00806	COG0254	rRNA binding
DSM104443_00807	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSM104443_00809	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DSM104443_00811	COG1294	oxidase, subunit
DSM104443_00812	COG1271	oxidase subunit
DSM104443_00815	COG1074	ATP-dependent DNA helicase activity
DSM104443_00819	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DSM104443_00822	COG3132	Protein of unknown function, DUF480
DSM104443_00824	COG2267	carboxylic ester hydrolase activity
DSM104443_00832	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DSM104443_00841	COG0756	dUTP diphosphatase activity
DSM104443_00842	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSM104443_00843	COG2003	Belongs to the UPF0758 family
DSM104443_00844	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSM104443_00845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSM104443_00849	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DSM104443_00849	COG3264	Mechanosensitive ion channel
DSM104443_00850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSM104443_00850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM104443_00853	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSM104443_00854	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSM104443_00858	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSM104443_00861	COG0617	tRNA 3'-terminal CCA addition
DSM104443_00863	COG1428	Deoxynucleoside kinase
DSM104443_00870	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSM104443_00871	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSM104443_00873	COG1380	Effector of murein hydrolase LrgA
DSM104443_00879	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104443_00880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_00882	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00884	COG4771	TonB-dependent receptor
DSM104443_00888	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00889	COG1024	Enoyl-CoA hydratase
DSM104443_00891	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104443_00893	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104443_00895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_00897	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_00898	COG0662	Cupin 2, conserved barrel domain protein
DSM104443_00902	COG1850	ribulose-bisphosphate carboxylase activity
DSM104443_00905	COG3008	intermembrane lipid transfer
DSM104443_00905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSM104443_00906	COG2995	paraquat-inducible protein a
DSM104443_00910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DSM104443_00910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DSM104443_00916	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DSM104443_00917	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSM104443_00918	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSM104443_00920	COG0243	molybdopterin cofactor binding
DSM104443_00922	COG1116	anion transmembrane transporter activity
DSM104443_00923	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104443_00924	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_00925	COG3707	response regulator
DSM104443_00927	COG2274	protein secretion by the type I secretion system
DSM104443_00928	COG2274	protein secretion by the type I secretion system
DSM104443_00943	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DSM104443_00946	COG0583	DNA-binding transcription factor activity
DSM104443_00949	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSM104443_00951	COG0697	spore germination
DSM104443_00952	COG2153	protein acetylation
DSM104443_00953	COG0354	folic acid binding
DSM104443_00955	COG0047	phosphoribosylformylglycinamidine synthase activity
DSM104443_00955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSM104443_00960	COG0745	RESPONSE REGULATOR receiver
DSM104443_00964	COG1595	DNA-templated transcription, initiation
DSM104443_00966	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104443_00968	COG2350	Protein conserved in bacteria
DSM104443_00969	COG2917	probably involved in intracellular septation
DSM104443_00971	COG0613	PHP domain protein
DSM104443_00972	COG0009	L-threonylcarbamoyladenylate synthase
DSM104443_00973	COG1994	Peptidase M50
DSM104443_00974	COG0180	Tryptophanyl-tRNA synthetase
DSM104443_00976	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DSM104443_00977	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSM104443_00981	COG0583	DNA-binding transcription factor activity
DSM104443_00984	COG1335	isochorismatase
DSM104443_00987	COG2084	Dehydrogenase
DSM104443_00990	COG0259	pyridoxamine-phosphate oxidase activity
DSM104443_00996	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104443_01001	COG2171	N-acyltransferase activity
DSM104443_01004	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104443_01007	COG2226	methyltransferase
DSM104443_01009	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSM104443_01010	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104443_01014	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DSM104443_01017	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSM104443_01018	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSM104443_01019	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSM104443_01021	COG0242	peptide deformylase activity
DSM104443_01028	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DSM104443_01029	COG0024	Methionine aminopeptidase
DSM104443_01030	COG0052	Belongs to the universal ribosomal protein uS2 family
DSM104443_01031	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DSM104443_01032	COG0528	UMP kinase activity
DSM104443_01033	COG0233	cytoplasmic translational termination
DSM104443_01034	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSM104443_01035	COG0575	Belongs to the CDS family
DSM104443_01036	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DSM104443_01040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104443_01041	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM104443_01042	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104443_01043	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104443_01044	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSM104443_01045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104443_01047	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSM104443_01049	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DSM104443_01051	COG2153	protein acetylation
DSM104443_01052	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_01054	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104443_01055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM104443_01060	COG0515	serine threonine protein kinase
DSM104443_01060	COG2815	serine threonine protein kinase
DSM104443_01063	COG1297	OPT oligopeptide transporter protein
DSM104443_01073	COG2226	methyltransferase
DSM104443_01084	COG0601	transmembrane transport
DSM104443_01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_01086	COG0444	Belongs to the ABC transporter superfamily
DSM104443_01087	COG4608	Belongs to the ABC transporter superfamily
DSM104443_01091	COG0251	oxidation-reduction process
DSM104443_01094	COG0640	Transcriptional regulator
DSM104443_01095	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_01100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSM104443_01118	COG1793	dna ligase
DSM104443_01118	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSM104443_01119	COG1793	dna ligase
DSM104443_01120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104443_01125	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
DSM104443_01126	COG1201	RNA secondary structure unwinding
DSM104443_01134	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSM104443_01135	COG0670	Belongs to the BI1 family
DSM104443_01143	COG0454	-acetyltransferase
DSM104443_01146	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_01147	COG2186	Transcriptional regulator
DSM104443_01148	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104443_01151	COG5001	Diguanylate cyclase
DSM104443_01152	COG0527	aspartate kinase activity
DSM104443_01153	COG1505	serine-type exopeptidase activity
DSM104443_01154	COG2982	Protein involved in outer membrane biogenesis
DSM104443_01156	COG0582	viral genome integration into host DNA
DSM104443_01171	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DSM104443_01172	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104443_01172	COG2205	protein histidine kinase activity
DSM104443_01180	COG0300	oxidoreductase activity
DSM104443_01185	COG2020	methyltransferase activity
DSM104443_01186	COG0596	Alpha beta hydrolase
DSM104443_01187	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DSM104443_01189	COG3300	MHYT domain
DSM104443_01189	COG5001	Diguanylate cyclase
DSM104443_01192	COG1612	heme a metabolic process
DSM104443_01194	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_01196	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104443_01198	COG2084	Dehydrogenase
DSM104443_01199	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104443_01201	COG4177	L-phenylalanine transmembrane transporter activity
DSM104443_01202	COG1137	ATPase activity
DSM104443_01204	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSM104443_01211	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104443_01217	COG0628	permease
DSM104443_01222	COG1012	belongs to the aldehyde dehydrogenase family
DSM104443_01223	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM104443_01227	COG2318	DinB family
DSM104443_01229	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSM104443_01233	COG1283	sodium-dependent phosphate transmembrane transporter activity
DSM104443_01234	COG1012	belongs to the aldehyde dehydrogenase family
DSM104443_01240	COG4172	Belongs to the ABC transporter superfamily
DSM104443_01241	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_01248	COG0583	DNA-binding transcription factor activity
DSM104443_01249	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM104443_01250	COG3842	ATPase activity
DSM104443_01252	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104443_01261	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM104443_01262	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DSM104443_01263	COG0321	lipoyl(octanoyl) transferase activity
DSM104443_01263	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DSM104443_01266	COG2850	peptidyl-arginine hydroxylation
DSM104443_01267	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_01270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSM104443_01274	COG1652	LysM domain
DSM104443_01275	COG1252	NADH dehydrogenase
DSM104443_01279	COG0483	inositol monophosphate 1-phosphatase activity
DSM104443_01282	COG1045	serine acetyltransferase
DSM104443_01284	COG1104	cysteine desulfurase activity
DSM104443_01285	COG0822	iron-sulfur transferase activity
DSM104443_01286	COG0316	Belongs to the HesB IscA family
DSM104443_01287	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DSM104443_01289	COG0443	Heat shock 70 kDa protein
DSM104443_01290	COG0633	Ferredoxin
DSM104443_01296	COG4772	TonB-dependent receptor
DSM104443_01297	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104443_01297	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM104443_01298	COG2204	response regulator
DSM104443_01300	COG2205	protein histidine kinase activity
DSM104443_01302	COG0560	Phosphoserine phosphatase
DSM104443_01303	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSM104443_01308	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104443_01310	COG5002	protein histidine kinase activity
DSM104443_01311	COG0745	RESPONSE REGULATOR receiver
DSM104443_01312	COG4566	intracellular signal transduction
DSM104443_01316	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSM104443_01325	COG0028	Belongs to the TPP enzyme family
DSM104443_01327	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSM104443_01328	COG0688	phosphatidylethanolamine metabolic process
DSM104443_01329	COG1183	phosphatidylcholine synthase activity
DSM104443_01331	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104443_01333	COG0656	L-ascorbic acid biosynthetic process
DSM104443_01336	COG0625	glutathione transferase activity
DSM104443_01337	COG0482	sulfurtransferase activity
DSM104443_01340	COG0538	isocitrate dehydrogenase activity
DSM104443_01341	COG1278	Cold shock
DSM104443_01342	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DSM104443_01343	COG0542	response to heat
DSM104443_01345	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSM104443_01346	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM104443_01347	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM104443_01348	COG1309	transcriptional regulator
DSM104443_01349	COG0433	COG0433 Predicted ATPase
DSM104443_01350	COG0217	transcriptional regulatory protein
DSM104443_01352	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSM104443_01353	COG0632	four-way junction helicase activity
DSM104443_01354	COG2255	four-way junction helicase activity
DSM104443_01355	COG0824	Thioesterase
DSM104443_01359	COG0823	Involved in the tonB-independent uptake of proteins
DSM104443_01361	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DSM104443_01362	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DSM104443_01367	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DSM104443_01368	COG1247	-acetyltransferase
DSM104443_01370	COG2205	protein histidine kinase activity
DSM104443_01372	COG4206	TonB-dependent receptor
DSM104443_01373	COG0779	Required for maturation of 30S ribosomal subunits
DSM104443_01374	COG0195	Participates in both transcription termination and antitermination
DSM104443_01374	COG2251	uridine kinase activity
DSM104443_01375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSM104443_01376	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DSM104443_01377	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSM104443_01378	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSM104443_01379	COG1185	polyribonucleotide nucleotidyltransferase activity
DSM104443_01384	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSM104443_01385	COG2867	negative regulation of translational initiation
DSM104443_01386	COG2914	Belongs to the UPF0125 (RnfH) family
DSM104443_01392	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104443_01392	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSM104443_01398	COG1393	Belongs to the ArsC family
DSM104443_01401	COG1254	Belongs to the acylphosphatase family
DSM104443_01403	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104443_01403	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104443_01404	COG0489	protein tyrosine kinase activity
DSM104443_01405	COG0717	Belongs to the dCTP deaminase family
DSM104443_01406	COG0019	diaminopimelate decarboxylase activity
DSM104443_01414	COG1476	TRANSCRIPTIONal
DSM104443_01420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DSM104443_01421	COG3104	oligopeptide transport
DSM104443_01428	COG1355	regulation of microtubule-based process
DSM104443_01429	COG2078	PFAM AMMECR1 domain protein
DSM104443_01432	COG1162	GTPase activity
DSM104443_01433	COG2154	pterin-4-alpha-carbinolamine dehydratase
DSM104443_01434	COG0501	Belongs to the peptidase M48B family
DSM104443_01435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DSM104443_01436	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DSM104443_01440	COG0395	ABC-type sugar transport system, permease component
DSM104443_01443	COG1546	Belongs to the CinA family
DSM104443_01444	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSM104443_01445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSM104443_01446	COG2137	regulation of response to DNA damage stimulus
DSM104443_01449	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSM104443_01451	COG0438	transferase activity, transferring glycosyl groups
DSM104443_01454	COG1131	(ABC) transporter
DSM104443_01456	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104443_01457	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104443_01458	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DSM104443_01459	COG0631	protein serine/threonine phosphatase activity
DSM104443_01462	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104443_01463	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DSM104443_01470	COG3258	Cytochrome c
DSM104443_01472	COG4783	chaperone-mediated protein folding
DSM104443_01473	COG0315	cyclic pyranopterin monophosphate synthase activity
DSM104443_01476	COG0425	Belongs to the sulfur carrier protein TusA family
DSM104443_01478	COG1024	Enoyl-CoA hydratase
DSM104443_01480	COG0525	valine-tRNA ligase activity
DSM104443_01483	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104443_01487	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DSM104443_01491	COG0493	'glutamate synthase
DSM104443_01491	COG0543	2 iron, 2 sulfur cluster binding
DSM104443_01492	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DSM104443_01494	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSM104443_01498	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSM104443_01505	COG1450	Type ii and iii secretion system protein
DSM104443_01506	COG3338	carbonate dehydratase activity
DSM104443_01507	COG1672	PFAM Archaeal ATPase
DSM104443_01507	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DSM104443_01511	COG1404	Belongs to the peptidase S8 family
DSM104443_01518	COG0471	metal ion transport
DSM104443_01520	COG1301	dicarboxylic acid transport
DSM104443_01522	COG4566	intracellular signal transduction
DSM104443_01523	COG2205	protein histidine kinase activity
DSM104443_01523	COG2198	Histidine kinase
DSM104443_01523	COG0784	Response regulator, receiver
DSM104443_01524	COG4191	Histidine kinase
DSM104443_01525	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSM104443_01527	COG3791	Glutathione-dependent formaldehyde-activating
DSM104443_01532	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSM104443_01534	COG3023	N-Acetylmuramoyl-L-alanine amidase
DSM104443_01535	COG4166	transmembrane transport
DSM104443_01536	COG0700	Nucleoside recognition
DSM104443_01541	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSM104443_01546	COG0204	Acyl-transferase
DSM104443_01550	COG0436	Aminotransferase
DSM104443_01554	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSM104443_01558	COG0322	excinuclease ABC activity
DSM104443_01563	COG0640	Transcriptional regulator
DSM104443_01566	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104443_01569	COG1917	Cupin 2, conserved barrel domain protein
DSM104443_01569	COG4977	sequence-specific DNA binding
DSM104443_01572	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104443_01574	COG1566	PFAM secretion protein HlyD family protein
DSM104443_01575	COG2814	Major facilitator Superfamily
DSM104443_01576	COG0066	3-isopropylmalate dehydratase activity
DSM104443_01577	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_01580	COG0101	tRNA pseudouridine synthase activity
DSM104443_01581	COG0135	phosphoribosylanthranilate isomerase activity
DSM104443_01582	COG0133	tryptophan synthase activity
DSM104443_01583	COG0159	tryptophan synthase activity
DSM104443_01584	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DSM104443_01585	COG0285	dihydrofolate synthase activity
DSM104443_01592	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DSM104443_01594	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSM104443_01597	COG0215	cysteine-tRNA ligase activity
DSM104443_01599	COG0484	heat shock protein binding
DSM104443_01600	COG0443	Heat shock 70 kDa protein
DSM104443_01601	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSM104443_01602	COG1950	PFAM Membrane protein of
DSM104443_01603	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DSM104443_01604	COG1420	regulation of RNA biosynthetic process
DSM104443_01605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSM104443_01606	COG0497	DNA recombination
DSM104443_01609	COG0400	carboxylic ester hydrolase activity
DSM104443_01610	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSM104443_01611	COG3028	Belongs to the UPF0307 family
DSM104443_01612	COG0312	modulator of DNA gyrase
DSM104443_01613	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104443_01615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSM104443_01616	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_01620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM104443_01621	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM104443_01622	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104443_01622	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DSM104443_01626	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DSM104443_01627	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM104443_01628	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DSM104443_01629	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DSM104443_01630	COG0584	glycerophosphoryl diester phosphodiesterase
DSM104443_01634	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104443_01635	COG0678	peroxiredoxin activity
DSM104443_01635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DSM104443_01636	COG0583	DNA-binding transcription factor activity
DSM104443_01641	COG0247	lactate metabolic process
DSM104443_01642	COG1592	Rubrerythrin
DSM104443_01647	COG2264	protein methyltransferase activity
DSM104443_01650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DSM104443_01659	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DSM104443_01662	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DSM104443_01664	COG2329	Antibiotic biosynthesis monooxygenase
DSM104443_01669	COG1174	glycine betaine transport
DSM104443_01671	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_01672	COG0129	dihydroxy-acid dehydratase activity
DSM104443_01673	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104443_01674	COG3842	ATPase activity
DSM104443_01676	COG1175	transmembrane transport
DSM104443_01677	COG3833	ABC-type maltose transport systems, permease component
DSM104443_01681	COG0484	heat shock protein binding
DSM104443_01684	COG0840	transmembrane signaling receptor activity
DSM104443_01685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104443_01686	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104443_01688	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_01691	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSM104443_01692	COG2721	sulfolactate sulfo-lyase activity
DSM104443_01693	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104443_01696	COG0154	amidase activity
DSM104443_01697	COG0596	Alpha beta hydrolase
DSM104443_01701	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104443_01705	COG0741	lytic transglycosylase activity
DSM104443_01706	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DSM104443_01707	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_01711	COG0517	IMP dehydrogenase activity
DSM104443_01712	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104443_01714	COG0187	DNA topoisomerase II activity
DSM104443_01715	COG0745	RESPONSE REGULATOR receiver
DSM104443_01716	COG2199	diguanylate cyclase activity
DSM104443_01716	COG2200	EAL domain
DSM104443_01716	COG2203	Gaf domain
DSM104443_01717	COG0784	Response regulator, receiver
DSM104443_01717	COG2205	protein histidine kinase activity
DSM104443_01719	COG1309	transcriptional regulator
DSM104443_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_01722	COG1538	Outer membrane efflux protein
DSM104443_01735	COG3128	pkhd-type hydroxylase
DSM104443_01738	COG2205	protein histidine kinase activity
DSM104443_01742	COG4251	negative regulation of phosphorylation
DSM104443_01744	COG4771	TonB-dependent receptor
DSM104443_01745	COG5002	protein histidine kinase activity
DSM104443_01746	COG0745	RESPONSE REGULATOR receiver
DSM104443_01749	COG0745	RESPONSE REGULATOR receiver
DSM104443_01752	COG0840	transmembrane signaling receptor activity
DSM104443_01753	COG0477	Major facilitator Superfamily
DSM104443_01761	COG0582	viral genome integration into host DNA
DSM104443_01776	COG2358	TRAP transporter, solute receptor (TAXI family
DSM104443_01777	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DSM104443_01783	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM104443_01801	COG1309	transcriptional regulator
DSM104443_01807	COG0697	spore germination
DSM104443_01812	COG1595	DNA-templated transcription, initiation
DSM104443_01816	COG1392	Phosphate transport regulator
DSM104443_01817	COG0306	phosphate transporter
DSM104443_01821	COG2828	Protein conserved in bacteria
DSM104443_01830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DSM104443_01832	COG2079	MmgE PrpD family protein
DSM104443_01837	COG2030	dehydratase
DSM104443_01838	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104443_01841	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DSM104443_01842	COG1053	succinate dehydrogenase
DSM104443_01843	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DSM104443_01844	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DSM104443_01845	COG0372	Belongs to the citrate synthase family
DSM104443_01846	COG0567	Dehydrogenase, E1 component
DSM104443_01847	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM104443_01851	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM104443_01852	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DSM104443_01853	COG0604	alcohol dehydrogenase
DSM104443_01858	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSM104443_01859	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_01863	COG1024	Enoyl-CoA hydratase
DSM104443_01872	COG0137	argininosuccinate synthase activity
DSM104443_01874	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM104443_01874	COG2022	thiamine diphosphate biosynthetic process
DSM104443_01878	COG1960	acyl-CoA dehydrogenase activity
DSM104443_01879	COG1971	Probably functions as a manganese efflux pump
DSM104443_01881	COG2133	pyrroloquinoline quinone binding
DSM104443_01886	COG5001	Diguanylate cyclase
DSM104443_01886	COG5002	protein histidine kinase activity
DSM104443_01888	COG1024	Enoyl-CoA hydratase
DSM104443_01889	COG1024	Enoyl-CoA hydratase
DSM104443_01892	COG2985	domain, Protein
DSM104443_01901	COG3119	arylsulfatase activity
DSM104443_01905	COG4566	intracellular signal transduction
DSM104443_01906	COG4191	Histidine kinase
DSM104443_01917	COG4770	biotin carboxylase activity
DSM104443_01919	COG1024	Enoyl-CoA hydratase
DSM104443_01920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104443_01923	COG1960	acyl-CoA dehydrogenase activity
DSM104443_01926	COG0183	Belongs to the thiolase family
DSM104443_01928	COG1960	acyl-CoA dehydrogenase activity
DSM104443_01932	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104443_01934	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_01935	COG0066	3-isopropylmalate dehydratase activity
DSM104443_01936	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104443_01938	COG0583	DNA-binding transcription factor activity
DSM104443_01939	COG2159	amidohydrolase
DSM104443_01940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSM104443_01943	COG1022	Amp-dependent synthetase and ligase
DSM104443_01945	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104443_01950	COG3842	ATPase activity
DSM104443_01951	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM104443_01955	COG0412	Dienelactone hydrolase
DSM104443_01959	COG4555	ABC transporter
DSM104443_01960	COG1668	transmembrane transport
DSM104443_01961	COG1199	ATP-dependent helicase activity
DSM104443_01965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM104443_01971	COG1214	PFAM Peptidase M22, glycoprotease
DSM104443_01973	COG1573	uracil-dna glycosylase
DSM104443_01977	COG1414	Transcriptional regulator
DSM104443_01979	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_01981	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DSM104443_01984	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSM104443_01985	COG4133	protoheme IX ABC transporter activity
DSM104443_01993	COG0492	ferredoxin-NADP+ reductase activity
DSM104443_01995	COG0477	Major facilitator Superfamily
DSM104443_02003	COG0745	RESPONSE REGULATOR receiver
DSM104443_02004	COG0643	Histidine kinase
DSM104443_02004	COG2198	Histidine kinase
DSM104443_02005	COG0840	transmembrane signaling receptor activity
DSM104443_02006	COG0840	transmembrane signaling receptor activity
DSM104443_02007	COG0835	chemotaxis
DSM104443_02008	COG0840	transmembrane signaling receptor activity
DSM104443_02010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSM104443_02011	COG2201	protein-glutamate methylesterase activity
DSM104443_02012	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM104443_02012	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSM104443_02013	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSM104443_02015	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DSM104443_02018	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DSM104443_02019	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_02021	COG0737	Belongs to the 5'-nucleotidase family
DSM104443_02021	COG1525	nuclease
DSM104443_02021	COG4085	toxin activity
DSM104443_02025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104443_02028	COG2346	COG2346, Truncated hemoglobins
DSM104443_02032	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DSM104443_02033	COG1322	Protein conserved in bacteria
DSM104443_02034	COG0028	Belongs to the TPP enzyme family
DSM104443_02037	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSM104443_02038	COG0596	Alpha beta hydrolase
DSM104443_02041	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_02044	COG4677	pectinesterase activity
DSM104443_02046	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DSM104443_02046	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DSM104443_02048	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DSM104443_02050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_02051	COG1609	Transcriptional regulator
DSM104443_02052	COG1763	Mo-molybdopterin cofactor biosynthetic process
DSM104443_02053	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DSM104443_02054	COG0314	molybdopterin synthase activity
DSM104443_02055	COG0640	Transcriptional regulator
DSM104443_02056	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DSM104443_02057	COG4654	Cytochrome c, class I
DSM104443_02063	COG0737	Belongs to the 5'-nucleotidase family
DSM104443_02084	COG0640	Transcriptional regulator
DSM104443_02085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSM104443_02087	COG0587	DNA-directed DNA polymerase activity
DSM104443_02090	COG4206	TonB-dependent receptor
DSM104443_02094	COG4771	TonB-dependent receptor
DSM104443_02097	COG0683	leucine binding
DSM104443_02098	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSM104443_02101	COG0561	phosphatase activity
DSM104443_02103	COG0297	glycogen (starch) synthase activity
DSM104443_02104	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSM104443_02105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DSM104443_02106	COG0366	Alpha amylase catalytic
DSM104443_02109	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DSM104443_02114	COG0673	inositol 2-dehydrogenase activity
DSM104443_02117	COG5002	protein histidine kinase activity
DSM104443_02119	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DSM104443_02121	COG0673	inositol 2-dehydrogenase activity
DSM104443_02123	COG2204	response regulator
DSM104443_02124	COG2204	response regulator
DSM104443_02125	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DSM104443_02127	COG3237	CsbD-like
DSM104443_02133	COG0114	fumarate hydratase activity
DSM104443_02134	COG3038	cytochrome b561
DSM104443_02136	COG2353	YceI-like domain
DSM104443_02139	COG0823	Involved in the tonB-independent uptake of proteins
DSM104443_02139	COG1506	peptidase
DSM104443_02139	COG4946	Tricorn protease homolog
DSM104443_02144	COG0672	)-iron permease
DSM104443_02145	COG4774	siderophore transport
DSM104443_02150	COG1960	acyl-CoA dehydrogenase activity
DSM104443_02155	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_02156	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DSM104443_02157	COG0247	lactate metabolic process
DSM104443_02157	COG0277	FAD linked oxidase domain protein
DSM104443_02158	COG1802	Transcriptional regulator
DSM104443_02159	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104443_02165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DSM104443_02166	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM104443_02167	COG2010	Cytochrome c
DSM104443_02167	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM104443_02169	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_02180	COG4221	oxidoreductase activity
DSM104443_02181	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM104443_02184	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104443_02185	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DSM104443_02187	COG0084	hydrolase, TatD family'
DSM104443_02188	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM104443_02191	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSM104443_02192	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSM104443_02193	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104443_02194	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM104443_02195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM104443_02196	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02198	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM104443_02199	COG0416	fatty acid biosynthetic process
DSM104443_02200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSM104443_02202	COG0424	maF-like protein
DSM104443_02203	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSM104443_02205	COG0616	signal peptide processing
DSM104443_02207	COG0546	phosphoglycolate phosphatase activity
DSM104443_02208	COG0564	pseudouridine synthase activity
DSM104443_02209	COG1530	ribonuclease E activity
DSM104443_02211	COG3209	COG3209 Rhs family protein
DSM104443_02215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSM104443_02217	COG0556	nucleotide-excision repair
DSM104443_02218	COG0436	Aminotransferase
DSM104443_02227	COG0281	malic enzyme
DSM104443_02228	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104443_02231	COG4585	Histidine kinase
DSM104443_02232	COG2197	response regulator
DSM104443_02233	COG2205	protein histidine kinase activity
DSM104443_02233	COG2202	Pas domain
DSM104443_02234	COG0784	Response regulator, receiver
DSM104443_02237	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DSM104443_02238	COG4251	negative regulation of phosphorylation
DSM104443_02244	COG0288	reversible hydration of carbon dioxide
DSM104443_02247	COG0667	Aldo Keto reductase
DSM104443_02250	COG4214	carbohydrate transport
DSM104443_02251	COG4213	ABC transporter substrate-binding protein
DSM104443_02252	COG2115	Belongs to the xylose isomerase family
DSM104443_02253	COG2115	Belongs to the xylose isomerase family
DSM104443_02254	COG1070	Carbohydrate kinase
DSM104443_02256	COG0395	ABC-type sugar transport system, permease component
DSM104443_02257	COG1175	transmembrane transport
DSM104443_02259	COG1609	Transcriptional regulator
DSM104443_02261	COG3661	Belongs to the glycosyl hydrolase 67 family
DSM104443_02262	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104443_02263	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104443_02283	COG3507	Belongs to the glycosyl hydrolase 43 family
DSM104443_02292	COG1566	PFAM secretion protein HlyD family protein
DSM104443_02293	COG1538	Outer membrane efflux protein
DSM104443_02297	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104443_02298	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_02299	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104443_02303	COG1187	pseudouridine synthase activity
DSM104443_02305	COG2264	protein methyltransferase activity
DSM104443_02308	COG0601	transmembrane transport
DSM104443_02309	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_02310	COG0444	Belongs to the ABC transporter superfamily
DSM104443_02311	COG4608	Belongs to the ABC transporter superfamily
DSM104443_02314	COG3246	L-lysine catabolic process to acetate
DSM104443_02316	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_02317	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104443_02327	COG1595	DNA-templated transcription, initiation
DSM104443_02329	COG2197	response regulator
DSM104443_02333	COG3781	membrane
DSM104443_02336	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSM104443_02349	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_02356	COG0596	Alpha beta hydrolase
DSM104443_02358	COG2197	response regulator
DSM104443_02359	COG4585	Histidine kinase
DSM104443_02360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_02363	COG0596	Alpha beta hydrolase
DSM104443_02364	COG0596	Alpha beta hydrolase
DSM104443_02366	COG4566	intracellular signal transduction
DSM104443_02367	COG4566	intracellular signal transduction
DSM104443_02373	COG0322	excinuclease ABC activity
DSM104443_02374	COG1472	Belongs to the glycosyl hydrolase 3 family
DSM104443_02375	COG0736	holo-[acyl-carrier-protein] synthase activity
DSM104443_02376	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DSM104443_02377	COG1381	Involved in DNA repair and RecF pathway recombination
DSM104443_02378	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSM104443_02379	COG0571	ribonuclease III activity
DSM104443_02381	COG0681	Belongs to the peptidase S26 family
DSM104443_02382	COG0481	GTPase activity
DSM104443_02384	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104443_02388	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSM104443_02389	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSM104443_02389	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSM104443_02391	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DSM104443_02391	COG0617	tRNA 3'-terminal CCA addition
DSM104443_02391	COG0517	IMP dehydrogenase activity
DSM104443_02393	COG1136	(ABC) transporter
DSM104443_02396	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DSM104443_02396	COG2755	lipolytic protein G-D-S-L family
DSM104443_02397	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104443_02400	COG1024	Enoyl-CoA hydratase
DSM104443_02401	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_02404	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104443_02407	COG0784	Response regulator, receiver
DSM104443_02407	COG2205	protein histidine kinase activity
DSM104443_02418	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_02419	COG2050	protein possibly involved in aromatic compounds catabolism
DSM104443_02420	COG0640	Transcriptional regulator
DSM104443_02422	COG3964	amidohydrolase
DSM104443_02441	COG2205	protein histidine kinase activity
DSM104443_02443	COG1183	phosphatidylcholine synthase activity
DSM104443_02446	COG0542	response to heat
DSM104443_02448	COG2853	Lipoprotein
DSM104443_02458	COG0436	Aminotransferase
DSM104443_02459	COG0484	heat shock protein binding
DSM104443_02463	COG2902	Dehydrogenase
DSM104443_02465	COG0765	amino acid transport
DSM104443_02466	COG0765	amino acid transport
DSM104443_02467	COG1126	abc transporter atp-binding protein
DSM104443_02469	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSM104443_02471	COG0714	Associated with various cellular activities
DSM104443_02474	COG0653	protein targeting
DSM104443_02476	COG4942	peptidase
DSM104443_02476	COG1388	LysM domain
DSM104443_02477	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSM104443_02478	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DSM104443_02479	COG3590	peptidase
DSM104443_02480	COG3590	peptidase
DSM104443_02481	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02483	COG0509	glycine decarboxylation via glycine cleavage system
DSM104443_02484	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSM104443_02485	COG2205	protein histidine kinase activity
DSM104443_02486	COG0156	8-amino-7-oxononanoate synthase activity
DSM104443_02491	COG0776	regulation of translation
DSM104443_02492	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM104443_02492	COG0072	phenylalanine-tRNA ligase activity
DSM104443_02493	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSM104443_02494	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSM104443_02495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSM104443_02496	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DSM104443_02497	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSM104443_02498	COG0683	leucine binding
DSM104443_02501	COG2159	amidohydrolase
DSM104443_02503	COG0583	DNA-binding transcription factor activity
DSM104443_02504	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DSM104443_02505	COG3384	dioxygenase
DSM104443_02510	COG0411	ABC transporter
DSM104443_02513	COG0683	leucine binding
DSM104443_02514	COG3485	protocatechuate 3,4-dioxygenase
DSM104443_02515	COG3485	protocatechuate 3,4-dioxygenase
DSM104443_02516	COG1414	Transcriptional regulator
DSM104443_02517	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DSM104443_02520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DSM104443_02521	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSM104443_02527	COG0829	nickel cation binding
DSM104443_02528	COG0831	urea catabolic process
DSM104443_02530	COG0804	urea catabolic process
DSM104443_02531	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DSM104443_02532	COG0830	nickel cation binding
DSM104443_02533	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DSM104443_02535	COG3754	Rhamnan synthesis protein F
DSM104443_02537	COG0456	acetyltransferase
DSM104443_02542	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM104443_02544	COG2308	Evidence 4 Homologs of previously reported genes of
DSM104443_02554	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DSM104443_02557	COG1136	(ABC) transporter
DSM104443_02560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSM104443_02562	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DSM104443_02565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSM104443_02567	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM104443_02568	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DSM104443_02569	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02570	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02571	COG3243	poly(R)-hydroxyalkanoic acid synthase
DSM104443_02574	COG0564	pseudouridine synthase activity
DSM104443_02576	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DSM104443_02581	COG5285	phytanoyl-CoA dioxygenase
DSM104443_02585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DSM104443_02586	COG4181	ATPase activity
DSM104443_02588	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DSM104443_02589	COG0515	serine threonine protein kinase
DSM104443_02589	COG2815	serine threonine protein kinase
DSM104443_02591	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DSM104443_02592	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSM104443_02593	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DSM104443_02595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSM104443_02596	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSM104443_02599	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104443_02600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM104443_02601	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104443_02602	COG0564	pseudouridine synthase activity
DSM104443_02603	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DSM104443_02604	COG1674	ftsk spoiiie
DSM104443_02606	COG0492	ferredoxin-NADP+ reductase activity
DSM104443_02607	COG1193	negative regulation of DNA recombination
DSM104443_02608	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DSM104443_02609	COG2076	Multidrug Resistance protein
DSM104443_02610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSM104443_02612	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104443_02612	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_02613	COG3548	integral membrane protein
DSM104443_02615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSM104443_02616	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DSM104443_02621	COG0347	Belongs to the P(II) protein family
DSM104443_02626	COG1596	polysaccharide export
DSM104443_02626	COG1555	photosystem II stabilization
DSM104443_02628	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_02629	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DSM104443_02631	COG0284	orotidine-5'-phosphate decarboxylase activity
DSM104443_02632	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DSM104443_02634	COG0776	regulation of translation
DSM104443_02636	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSM104443_02637	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSM104443_02638	COG0287	Prephenate dehydrogenase
DSM104443_02641	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSM104443_02642	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DSM104443_02645	COG0402	S-adenosylhomocysteine deaminase activity
DSM104443_02646	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104443_02650	COG1794	racemase activity, acting on amino acids and derivatives
DSM104443_02655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DSM104443_02659	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104443_02662	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104443_02667	COG2032	superoxide dismutase activity
DSM104443_02671	COG0437	4 iron, 4 sulfur cluster binding
DSM104443_02672	COG0243	molybdopterin cofactor binding
DSM104443_02672	COG3383	formate dehydrogenase (NAD+) activity
DSM104443_02678	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSM104443_02679	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSM104443_02680	COG0746	molybdenum cofactor guanylyltransferase activity
DSM104443_02682	COG0303	'Molybdopterin
DSM104443_02687	COG1309	transcriptional regulator
DSM104443_02688	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_02692	COG0583	DNA-binding transcription factor activity
DSM104443_02695	COG0175	sulfate reduction
DSM104443_02696	COG0175	sulfate reduction
DSM104443_02699	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DSM104443_02701	COG4208	sulfate ABC transporter
DSM104443_02702	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSM104443_02705	COG0450	alkyl hydroperoxide reductase
DSM104443_02706	COG0583	DNA-binding transcription factor activity
DSM104443_02707	COG0431	NADPH-dependent FMN reductase
DSM104443_02708	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_02709	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DSM104443_02710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_02711	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104443_02713	COG1116	anion transmembrane transporter activity
DSM104443_02716	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DSM104443_02717	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DSM104443_02718	COG0167	dihydroorotate dehydrogenase activity
DSM104443_02719	COG0686	Belongs to the AlaDH PNT family
DSM104443_02720	COG2878	Part of a membrane complex involved in electron transport
DSM104443_02721	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSM104443_02724	COG2863	cytochrome
DSM104443_02726	COG1595	DNA-templated transcription, initiation
DSM104443_02727	COG5001	Diguanylate cyclase
DSM104443_02727	COG5002	protein histidine kinase activity
DSM104443_02729	COG0328	RNA-DNA hybrid ribonuclease activity
DSM104443_02731	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM104443_02732	COG0456	acetyltransferase
DSM104443_02733	COG3903	Transcriptional regulator
DSM104443_02733	COG2319	Wd-40 repeat
DSM104443_02737	COG1388	LysM domain
DSM104443_02737	COG0741	lytic transglycosylase activity
DSM104443_02738	COG0339	signal peptide processing
DSM104443_02740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_02741	COG0601	transmembrane transport
DSM104443_02742	COG4166	transmembrane transport
DSM104443_02743	COG4166	transmembrane transport
DSM104443_02746	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM104443_02750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSM104443_02751	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSM104443_02752	COG0740	serine-type endopeptidase activity
DSM104443_02753	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSM104443_02755	COG1562	ergosterol biosynthetic process
DSM104443_02757	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DSM104443_02761	COG0515	serine threonine protein kinase
DSM104443_02761	COG2815	serine threonine protein kinase
DSM104443_02764	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DSM104443_02766	COG0359	binds to the 23S rRNA
DSM104443_02767	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSM104443_02769	COG0360	Binds together with S18 to 16S ribosomal RNA
DSM104443_02780	COG0612	Peptidase, M16
DSM104443_02781	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_02789	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSM104443_02793	COG1216	Glycosyl transferase, family 2
DSM104443_02800	COG0438	transferase activity, transferring glycosyl groups
DSM104443_02801	COG2226	methyltransferase
DSM104443_02803	COG0667	Aldo Keto reductase
DSM104443_02804	COG0438	transferase activity, transferring glycosyl groups
DSM104443_02808	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM104443_02809	COG2192	nodulation
DSM104443_02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_02811	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DSM104443_02812	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104443_02813	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSM104443_02815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM104443_02816	COG0557	exoribonuclease II activity
DSM104443_02819	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSM104443_02820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DSM104443_02822	COG0330	HflC and HflK could
DSM104443_02823	COG0330	HflC and HflK could
DSM104443_02824	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSM104443_02825	COG1923	regulation of RNA biosynthetic process
DSM104443_02826	COG1160	GTP binding
DSM104443_02828	COG2976	Protein conserved in bacteria
DSM104443_02829	COG0124	histidyl-tRNA synthetase
DSM104443_02830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSM104443_02833	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSM104443_02835	COG0037	tRNA processing
DSM104443_02836	COG0825	malonyl-CoA metabolic process
DSM104443_02837	COG2096	Adenosyltransferase
DSM104443_02838	COG1595	DNA-templated transcription, initiation
DSM104443_02840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DSM104443_02842	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSM104443_02844	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSM104443_02845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DSM104443_02849	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM104443_02853	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM104443_02856	COG0463	Glycosyl transferase, family 2
DSM104443_02858	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_02859	COG0312	modulator of DNA gyrase
DSM104443_02861	COG3164	Protein of unknown function
DSM104443_02862	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DSM104443_02866	COG0859	PFAM glycosyl transferase family 9
DSM104443_02869	COG5642	Protein of unknown function (DUF2384)
DSM104443_02870	COG5654	RES domain protein
DSM104443_02872	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_02887	COG2165	general secretion pathway protein
DSM104443_02890	COG3156	type II secretion system protein K
DSM104443_02894	COG0429	hydrolase of the alpha beta-hydrolase fold
DSM104443_02905	COG3064	Membrane
DSM104443_02908	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DSM104443_02912	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DSM104443_02913	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM104443_02914	COG2188	Transcriptional regulator
DSM104443_02916	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DSM104443_02917	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM104443_02917	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104443_02918	COG1263	PTS System
DSM104443_02918	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM104443_02918	COG2190	(PTS) system
DSM104443_02920	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02922	COG0625	glutathione transferase activity
DSM104443_02928	COG0625	glutathione transferase activity
DSM104443_02937	COG1132	(ABC) transporter
DSM104443_02940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DSM104443_02943	COG2353	YceI-like domain
DSM104443_02945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_02946	COG3647	Membrane
DSM104443_02947	COG1940	carbohydrate kinase activity
DSM104443_02951	COG0683	leucine binding
DSM104443_02959	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DSM104443_02960	COG0861	Integral membrane protein TerC family
DSM104443_02962	COG0625	glutathione transferase activity
DSM104443_02963	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DSM104443_02964	COG3540	Alkaline phosphatase
DSM104443_02967	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02970	COG1733	regulation of RNA biosynthetic process
DSM104443_02973	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_02978	COG1228	amidohydrolase
DSM104443_02981	COG3158	transport of potassium into the cell
DSM104443_02984	COG2135	peptidase activity
DSM104443_02985	COG0322	excinuclease ABC activity
DSM104443_02986	COG0583	DNA-binding transcription factor activity
DSM104443_02992	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DSM104443_02993	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DSM104443_02994	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSM104443_02995	COG0842	Transport permease protein
DSM104443_02996	COG1131	(ABC) transporter
DSM104443_02999	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_03017	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSM104443_03020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSM104443_03023	COG1538	Outer membrane efflux protein
DSM104443_03025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_03028	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_03031	COG3459	Glycosyltransferase 36 associated
DSM104443_03047	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104443_03048	COG1278	Cold shock
DSM104443_03062	COG2755	lipolytic protein G-D-S-L family
DSM104443_03064	COG2197	response regulator
DSM104443_03068	COG4681	YaeQ
DSM104443_03070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DSM104443_03071	COG0583	DNA-binding transcription factor activity
DSM104443_03072	COG4941	Belongs to the sigma-70 factor family
DSM104443_03074	COG3795	YCII-related domain
DSM104443_03076	COG3795	YCII-related domain
DSM104443_03081	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_03084	COG3275	phosphorelay sensor kinase activity
DSM104443_03085	COG3279	Response regulator of the LytR AlgR family
DSM104443_03089	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DSM104443_03097	COG1309	transcriptional regulator
DSM104443_03098	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DSM104443_03101	COG1538	Outer membrane efflux protein
DSM104443_03103	COG0583	DNA-binding transcription factor activity
DSM104443_03104	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DSM104443_03108	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSM104443_03112	COG1678	Uncharacterized ACR, COG1678
DSM104443_03115	COG0457	Tetratricopeptide repeat
DSM104443_03115	COG3710	Transcriptional regulator
DSM104443_03118	COG2301	Belongs to the HpcH HpaI aldolase family
DSM104443_03119	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DSM104443_03119	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_03120	COG0583	DNA-binding transcription factor activity
DSM104443_03122	COG0697	spore germination
DSM104443_03123	COG1764	response to oxidative stress
DSM104443_03127	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104443_03128	COG0765	amino acid transport
DSM104443_03129	COG0765	amino acid transport
DSM104443_03132	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104443_03137	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104443_03138	COG4771	TonB-dependent receptor
DSM104443_03140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM104443_03141	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DSM104443_03142	COG2080	2 iron, 2 sulfur cluster binding
DSM104443_03143	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104443_03144	COG1690	Belongs to the RtcB family
DSM104443_03146	COG0297	glycogen (starch) synthase activity
DSM104443_03147	COG0431	NADPH-dependent FMN reductase
DSM104443_03149	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104443_03152	COG1522	sequence-specific DNA binding
DSM104443_03154	COG0165	Argininosuccinate lyase
DSM104443_03156	COG0583	DNA-binding transcription factor activity
DSM104443_03159	COG1733	regulation of RNA biosynthetic process
DSM104443_03162	COG1024	Enoyl-CoA hydratase
DSM104443_03166	COG0667	Aldo Keto reductase
DSM104443_03171	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_03175	COG2272	Belongs to the type-B carboxylesterase lipase family
DSM104443_03177	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_03181	COG0559	Belongs to the binding-protein-dependent transport system permease family
DSM104443_03185	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_03187	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_03194	COG3118	belongs to the thioredoxin family
DSM104443_03208	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM104443_03208	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM104443_03211	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DSM104443_03221	COG2205	protein histidine kinase activity
DSM104443_03222	COG0745	RESPONSE REGULATOR receiver
DSM104443_03227	COG0142	geranyltranstransferase activity
DSM104443_03228	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSM104443_03229	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSM104443_03230	COG1280	lysine exporter protein (LysE YggA)
DSM104443_03231	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSM104443_03232	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DSM104443_03237	COG0494	nUDIX hydrolase
DSM104443_03238	COG0442	prolyl-tRNA aminoacylation
DSM104443_03239	COG0519	Catalyzes the synthesis of GMP from XMP
DSM104443_03240	COG0741	lytic transglycosylase activity
DSM104443_03241	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_03243	COG1959	2 iron, 2 sulfur cluster binding
DSM104443_03243	COG1295	ribonuclease BN
DSM104443_03247	COG0586	Pfam SNARE associated Golgi protein
DSM104443_03248	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104443_03249	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DSM104443_03250	COG1862	Preprotein translocase
DSM104443_03251	COG0343	queuine tRNA-ribosyltransferase activity
DSM104443_03253	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSM104443_03254	COG0205	6-phosphofructokinase activity
DSM104443_03255	COG0563	adenylate kinase activity
DSM104443_03257	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DSM104443_03258	COG2835	tetraacyldisaccharide 4'-kinase activity
DSM104443_03260	COG0848	biopolymer transport protein
DSM104443_03262	COG1570	exodeoxyribonuclease VII activity
DSM104443_03263	COG3360	Dodecin
DSM104443_03264	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSM104443_03265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSM104443_03267	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM104443_03268	COG0802	atpase or kinase
DSM104443_03269	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSM104443_03274	COG5001	Diguanylate cyclase
DSM104443_03274	COG3300	MHYT domain
DSM104443_03280	COG4149	molybdate abc transporter
DSM104443_03281	COG3842	ATPase activity
DSM104443_03285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DSM104443_03290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSM104443_03293	COG0438	transferase activity, transferring glycosyl groups
DSM104443_03300	COG1295	ribonuclease BN
DSM104443_03305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DSM104443_03306	COG3639	organic phosphonate transmembrane transporter activity
DSM104443_03307	COG3639	organic phosphonate transmembrane transporter activity
DSM104443_03309	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DSM104443_03310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DSM104443_03311	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DSM104443_03312	COG2205	protein histidine kinase activity
DSM104443_03313	COG0745	RESPONSE REGULATOR receiver
DSM104443_03315	COG0387	Pfam Sodium calcium exchanger
DSM104443_03317	COG2095	MarC family integral membrane protein
DSM104443_03319	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_03320	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_03324	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DSM104443_03325	COG0148	phosphopyruvate hydratase activity
DSM104443_03331	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DSM104443_03351	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSM104443_03352	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DSM104443_03353	COG0504	CTP synthase activity
DSM104443_03356	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DSM104443_03357	COG2943	transferase activity, transferring hexosyl groups
DSM104443_03358	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_03363	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSM104443_03365	COG2897	thiosulfate sulfurtransferase activity
DSM104443_03373	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM104443_03379	COG0251	oxidation-reduction process
DSM104443_03381	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM104443_03385	COG0166	Belongs to the GPI family
DSM104443_03387	COG0598	Magnesium transport protein CorA
DSM104443_03391	COG1007	ATP synthesis coupled electron transport
DSM104443_03394	COG0713	ATP synthesis coupled electron transport
DSM104443_03395	COG0839	Belongs to the complex I subunit 6 family
DSM104443_03396	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104443_03397	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DSM104443_03398	COG1034	ATP synthesis coupled electron transport
DSM104443_03399	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DSM104443_03402	COG0649	NAD binding
DSM104443_03403	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104443_03404	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104443_03405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSM104443_03408	COG0149	triose-phosphate isomerase activity
DSM104443_03412	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM104443_03413	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSM104443_03414	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM104443_03415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSM104443_03416	COG1534	Rna-binding protein
DSM104443_03417	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM104443_03418	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM104443_03419	COG0505	Belongs to the CarA family
DSM104443_03420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSM104443_03421	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DSM104443_03422	COG0735	belongs to the Fur family
DSM104443_03427	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_03428	COG0783	Belongs to the Dps family
DSM104443_03430	COG1741	Belongs to the pirin family
DSM104443_03431	COG2259	Doxx family
DSM104443_03432	COG1741	Belongs to the pirin family
DSM104443_03433	COG0583	DNA-binding transcription factor activity
DSM104443_03434	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM104443_03444	COG0473	3-isopropylmalate dehydrogenase activity
DSM104443_03445	COG0596	Alpha beta hydrolase
DSM104443_03446	COG0318	PFAM AMP-dependent synthetase and ligase
DSM104443_03448	COG0515	serine threonine protein kinase
DSM104443_03448	COG2815	serine threonine protein kinase
DSM104443_03450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DSM104443_03454	COG1881	PFAM PEBP family protein
DSM104443_03455	COG0545	Peptidyl-prolyl cis-trans isomerase
DSM104443_03456	COG0405	Gamma-glutamyltransferase
DSM104443_03458	COG0747	negative chemotaxis
DSM104443_03463	COG0546	phosphoglycolate phosphatase activity
DSM104443_03463	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSM104443_03468	COG0747	negative chemotaxis
DSM104443_03472	COG3186	Phenylalanine-4-hydroxylase
DSM104443_03474	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DSM104443_03478	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSM104443_03479	COG0747	negative chemotaxis
DSM104443_03480	COG0601	transmembrane transport
DSM104443_03481	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM104443_03485	COG4608	Belongs to the ABC transporter superfamily
DSM104443_03491	COG5001	Diguanylate cyclase
DSM104443_03491	COG2203	Gaf domain
DSM104443_03491	COG3706	GGDEF domain
DSM104443_03491	COG4251	negative regulation of phosphorylation
DSM104443_03493	COG1643	Atp-dependent helicase
DSM104443_03501	COG0625	glutathione transferase activity
DSM104443_03502	COG2084	Dehydrogenase
DSM104443_03503	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM104443_03506	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DSM104443_03510	COG0247	lactate metabolic process
DSM104443_03511	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DSM104443_03513	COG1686	Belongs to the peptidase S11 family
DSM104443_03517	COG5265	(ABC) transporter
DSM104443_03520	COG3622	Belongs to the hyi family
DSM104443_03521	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM104443_03532	COG3383	formate dehydrogenase (NAD+) activity
DSM104443_03536	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DSM104443_03537	COG0045	succinate-CoA ligase (ADP-forming) activity
DSM104443_03538	COG1733	regulation of RNA biosynthetic process
DSM104443_03547	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM104443_03550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_03557	COG0861	Integral membrane protein TerC family
DSM104443_03558	COG0741	lytic transglycosylase activity
DSM104443_03560	COG0617	tRNA 3'-terminal CCA addition
DSM104443_03562	COG2358	TRAP transporter, solute receptor (TAXI family
DSM104443_03563	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DSM104443_03564	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DSM104443_03567	COG0037	tRNA processing
DSM104443_03568	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM104443_03570	COG4783	chaperone-mediated protein folding
DSM104443_03575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSM104443_03576	COG0625	glutathione transferase activity
DSM104443_03577	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSM104443_03579	COG1560	Kdo2-lipid A biosynthetic process
DSM104443_03580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSM104443_03582	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DSM104443_03583	COG0523	cobalamin synthesis protein
DSM104443_03584	COG0523	cobalamin synthesis protein
DSM104443_03585	COG1136	(ABC) transporter
DSM104443_03589	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DSM104443_03590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DSM104443_03594	COG3220	belongs to the UPF0276 family
DSM104443_03599	COG0071	Belongs to the small heat shock protein (HSP20) family
DSM104443_03600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSM104443_03601	COG3568	Endonuclease Exonuclease Phosphatase
DSM104443_03603	COG1446	asparaginase
DSM104443_03604	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSM104443_03608	COG0501	Belongs to the peptidase M48B family
DSM104443_03613	COG0629	single-stranded DNA binding
DSM104443_03614	COG2814	Major facilitator Superfamily
DSM104443_03619	COG0203	ribosomal protein L17
DSM104443_03620	COG0202	RNA polymerase activity
DSM104443_03621	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSM104443_03623	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSM104443_03624	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSM104443_03625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSM104443_03626	COG0201	protein transport
DSM104443_03627	COG0200	Binds to the 23S rRNA
DSM104443_03628	COG1841	ribosomal large subunit assembly
DSM104443_03629	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSM104443_03630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSM104443_03631	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSM104443_03632	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSM104443_03634	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSM104443_03635	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSM104443_03636	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSM104443_03637	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSM104443_03638	COG0255	Belongs to the universal ribosomal protein uL29 family
DSM104443_03639	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DSM104443_03641	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSM104443_03642	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSM104443_03643	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSM104443_03644	COG0089	rRNA binding
DSM104443_03645	COG0088	Forms part of the polypeptide exit tunnel
DSM104443_03646	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSM104443_03647	COG0051	transcription antitermination factor activity, RNA binding
DSM104443_03649	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM104443_03650	COG0049	tRNA binding
DSM104443_03651	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSM104443_03652	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSM104443_03653	COG0085	RNA polymerase activity
DSM104443_03654	COG0222	ribosome binding
DSM104443_03655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSM104443_03656	COG0081	regulation of translation
DSM104443_03657	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSM104443_03659	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DSM104443_03666	COG2969	positive regulation of protein catabolic process
DSM104443_03667	COG0625	glutathione transferase activity
DSM104443_03668	COG2857	Cytochrome c1
DSM104443_03669	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DSM104443_03670	COG0723	plastoquinol--plastocyanin reductase activity
DSM104443_03671	COG1970	mechanosensitive ion channel activity
DSM104443_03673	COG0805	protein transport
DSM104443_03674	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104443_03675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DSM104443_03677	COG0140	phosphoribosyl-ATP diphosphatase activity
DSM104443_03678	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSM104443_03680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSM104443_03681	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSM104443_03682	COG0131	Imidazoleglycerol-phosphate dehydratase
DSM104443_03683	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM104443_03684	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSM104443_03686	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSM104443_03688	COG0842	Transport permease protein
DSM104443_03689	COG1131	(ABC) transporter
DSM104443_03691	COG2854	intermembrane phospholipid transfer
DSM104443_03692	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DSM104443_03693	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DSM104443_03694	COG1127	ABC transporter
DSM104443_03696	COG3267	Type II secretory pathway component ExeA
DSM104443_03696	COG3409	Peptidoglycan-binding domain 1 protein
DSM104443_03699	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104443_03706	COG1469	GTP cyclohydrolase I activity
DSM104443_03710	COG1666	GTP binding
DSM104443_03713	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSM104443_03714	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM104443_03715	COG0268	Binds directly to 16S ribosomal RNA
DSM104443_03717	COG0196	riboflavin kinase activity
DSM104443_03718	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSM104443_03719	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSM104443_03720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSM104443_03731	COG5487	UPF0391 membrane protein
DSM104443_03733	COG0859	PFAM glycosyl transferase family 9
DSM104443_03733	COG0457	Tetratricopeptide repeat
DSM104443_03734	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM104443_03735	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DSM104443_03736	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DSM104443_03737	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DSM104443_03737	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSM104443_03738	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSM104443_03740	COG0754	glutathionylspermidine amidase activity
DSM104443_03742	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSM104443_03743	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DSM104443_03744	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSM104443_03746	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSM104443_03749	COG0126	phosphoglycerate kinase activity
DSM104443_03750	COG0469	pyruvate kinase activity
DSM104443_03755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSM104443_03762	COG1253	flavin adenine dinucleotide binding
DSM104443_03763	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM104443_03764	COG0730	response to heat
DSM104443_03778	COG0859	PFAM glycosyl transferase family 9
DSM104443_03780	COG1132	(ABC) transporter
DSM104443_03781	COG0297	glycogen (starch) synthase activity
DSM104443_03798	COG1450	Type ii and iii secretion system protein
DSM104443_03802	COG3156	type II secretion system protein K
DSM104443_03804	COG2165	general secretion pathway protein
DSM104443_03806	COG2165	general secretion pathway protein
DSM104443_03807	COG1459	type II secretion system
DSM104443_03808	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM104443_03809	COG0004	ammonium transporteR
DSM104443_03810	COG0347	Belongs to the P(II) protein family
DSM104443_03813	COG0606	chelatase, subunit chli
DSM104443_03814	COG2814	Major facilitator Superfamily
DSM104443_03819	COG1473	amidohydrolase
DSM104443_03820	COG1280	lysine exporter protein (LysE YggA)
DSM104443_03827	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104443_03841	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_03845	COG1902	pentaerythritol trinitrate reductase activity
DSM104443_03846	COG0625	glutathione transferase activity
DSM104443_03850	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_03852	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSM104443_03853	COG0142	geranyltranstransferase activity
DSM104443_03854	COG1722	exodeoxyribonuclease VII activity
DSM104443_03874	COG0745	RESPONSE REGULATOR receiver
DSM104443_03875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DSM104443_03876	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DSM104443_03879	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSM104443_03882	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM104443_03883	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DSM104443_03892	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DSM104443_03897	COG2855	membrane
DSM104443_03898	COG2721	sulfolactate sulfo-lyase activity
DSM104443_03899	COG2721	sulfolactate sulfo-lyase activity
DSM104443_03902	COG2321	neutral zinc metallopeptidase
DSM104443_03904	COG0336	Belongs to the RNA methyltransferase TrmD family
DSM104443_03905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSM104443_03906	COG0228	four-way junction DNA binding
DSM104443_03910	COG3011	Protein conserved in bacteria
DSM104443_03912	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSM104443_03913	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DSM104443_03914	COG4536	flavin adenine dinucleotide binding
DSM104443_03925	COG3483	tryptophan 2,3-dioxygenase activity
DSM104443_03930	COG2885	chlorophyll binding
DSM104443_03931	COG2208	phosphoserine phosphatase activity
DSM104443_03931	COG2770	Histidine kinase
DSM104443_03932	COG1234	tRNA 3'-trailer cleavage
DSM104443_03933	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM104443_03935	COG3180	Ammonia monooxygenase
DSM104443_03936	COG1609	Transcriptional regulator
DSM104443_03940	COG3386	PFAM SMP-30 Gluconolaconase
DSM104443_03943	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_03957	COG0714	Associated with various cellular activities
DSM104443_03965	COG1942	4-Oxalocrotonate Tautomerase
DSM104443_03967	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM104443_03970	COG0583	DNA-binding transcription factor activity
DSM104443_03977	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_03978	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_03980	COG2079	MmgE PrpD family protein
DSM104443_03986	COG0583	DNA-binding transcription factor activity
DSM104443_03993	COG0583	DNA-binding transcription factor activity
DSM104443_03995	COG1764	response to oxidative stress
DSM104443_04000	COG2197	response regulator
DSM104443_04006	COG4575	ribosome binding
DSM104443_04009	COG0584	glycerophosphoryl diester phosphodiesterase
DSM104443_04013	COG3181	Tripartite tricarboxylate transporter family receptor
DSM104443_04017	COG0457	Tetratricopeptide repeat
DSM104443_04018	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DSM104443_04020	COG1741	Belongs to the pirin family
DSM104443_04021	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104443_04022	COG0793	Belongs to the peptidase S41A family
DSM104443_04022	COG4946	Tricorn protease homolog
DSM104443_04023	COG2205	protein histidine kinase activity
DSM104443_04027	COG2951	lytic endotransglycosylase activity
DSM104443_04029	COG2081	HI0933 family
DSM104443_04031	COG0667	Aldo Keto reductase
DSM104443_04033	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_04037	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DSM104443_04040	COG1131	(ABC) transporter
DSM104443_04046	COG0793	Belongs to the peptidase S41A family
DSM104443_04049	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DSM104443_04052	COG0459	protein refolding
DSM104443_04056	COG2205	protein histidine kinase activity
DSM104443_04057	COG0784	Response regulator, receiver
DSM104443_04057	COG2198	Histidine kinase
DSM104443_04057	COG2205	protein histidine kinase activity
DSM104443_04060	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM104443_04061	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM104443_04062	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM104443_04066	COG2027	D-alanyl-D-alanine carboxypeptidase
DSM104443_04069	COG1960	acyl-CoA dehydrogenase activity
DSM104443_04070	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DSM104443_04074	COG1981	membrane
DSM104443_04075	COG4232	protein-disulfide reductase activity
DSM104443_04083	COG2945	thiolester hydrolase activity
DSM104443_04084	COG3411	Ferredoxin
DSM104443_04090	COG2972	Histidine kinase
DSM104443_04092	COG3275	phosphorelay sensor kinase activity
DSM104443_04095	COG3275	phosphorelay sensor kinase activity
DSM104443_04099	COG3842	ATPase activity
DSM104443_04101	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM104443_04103	COG0395	ABC-type sugar transport system, permease component
DSM104443_04107	COG4946	Tricorn protease homolog
DSM104443_04107	COG1506	peptidase
DSM104443_04107	COG0823	Involved in the tonB-independent uptake of proteins
DSM104443_04109	COG1028	Short-chain dehydrogenase reductase Sdr
DSM104443_04110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DSM104443_04113	COG0515	serine threonine protein kinase
DSM104443_04115	COG2814	Major facilitator Superfamily
DSM104443_04119	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_04125	COG0745	RESPONSE REGULATOR receiver
DSM104443_04126	COG2205	protein histidine kinase activity
DSM104443_04128	COG2226	methyltransferase
DSM104443_04131	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM104443_04132	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM104443_04139	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_04140	COG2813	Specifically methylates the guanine in position
DSM104443_04140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DSM104443_04141	COG2223	nitrite transmembrane transporter activity
DSM104443_04142	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM104443_04144	COG0488	(ABC) transporter
DSM104443_04145	COG0708	Exodeoxyribonuclease III
DSM104443_04146	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSM104443_04148	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104443_04149	COG0154	amidase activity
DSM104443_04150	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSM104443_04151	COG1077	Cell shape determining protein MreB Mrl
DSM104443_04152	COG1792	Involved in formation and maintenance of cell shape
DSM104443_04153	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DSM104443_04154	COG0768	penicillin binding
DSM104443_04155	COG0772	Belongs to the SEDS family
DSM104443_04157	COG1686	Belongs to the peptidase S11 family
DSM104443_04158	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM104443_04159	COG2921	Belongs to the UPF0250 family
DSM104443_04160	COG0321	lipoyl(octanoyl) transferase activity
DSM104443_04165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DSM104443_04169	COG3275	phosphorelay sensor kinase activity
DSM104443_04170	COG0165	Argininosuccinate lyase
DSM104443_04172	COG1965	Belongs to the frataxin family
DSM104443_04176	COG2239	Acts as a magnesium transporter
DSM104443_04177	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSM104443_04178	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSM104443_04179	COG0174	glutamine synthetase
DSM104443_04181	COG3852	Histidine kinase
DSM104443_04182	COG2204	response regulator
DSM104443_04186	COG0339	signal peptide processing
DSM104443_04188	COG0540	Belongs to the ATCase OTCase family
DSM104443_04189	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DSM104443_04190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DSM104443_04191	COG1678	Uncharacterized ACR, COG1678
DSM104443_04192	COG0415	Belongs to the DNA photolyase family
DSM104443_04200	COG3150	esterase
DSM104443_04202	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM104443_04205	COG0189	ligase activity
DSM104443_04210	COG1238	metal cluster binding
DSM104443_04211	COG0181	hydroxymethylbilane synthase activity
DSM104443_04213	COG2959	enzyme of heme biosynthesis
DSM104443_04216	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSM104443_04219	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DSM104443_04220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DSM104443_04221	COG0511	ligase activity, forming carbon-carbon bonds
DSM104443_04222	COG0439	Biotin carboxylase
DSM104443_04223	COG2264	protein methyltransferase activity
DSM104443_04226	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM104443_04229	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DSM104443_04230	COG3245	cytochrome
DSM104443_04232	COG3307	-O-antigen
DSM104443_04235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM104443_04239	COG0069	glutamate synthase activity
DSM104443_04239	COG0070	glutamate synthase
DSM104443_04239	COG0067	glutamate synthase
DSM104443_04242	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DSM104443_04243	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSM104443_04244	COG0018	arginyl-trna synthetase
DSM104443_04247	COG0300	oxidoreductase activity
DSM104443_04248	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM104443_04250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM104443_04251	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM104443_04252	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DSM104443_04254	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DSM104443_04257	COG0488	(ABC) transporter
DSM104443_04259	COG3590	peptidase
DSM104443_04261	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSM104443_04263	COG2271	Major facilitator Superfamily
DSM104443_04264	COG1404	Belongs to the peptidase S8 family
DSM104443_04271	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM104443_04272	COG4597	amino acid ABC transporter
DSM104443_04273	COG0765	amino acid transport
DSM104443_04274	COG1126	abc transporter atp-binding protein
DSM104443_04276	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSM104443_04281	COG0583	DNA-binding transcription factor activity
DSM104443_04283	COG0477	Major facilitator Superfamily
DSM104443_04286	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM104443_04291	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM104443_04293	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSM104443_04294	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSM104443_04295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSM104443_04296	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSM104443_04297	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSM104443_04298	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM104443_04299	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSM104443_04301	COG0356	it plays a direct role in the translocation of protons across the membrane
DSM104443_04303	COG1475	DNA binding
DSM104443_04304	COG1192	Involved in chromosome partitioning
DSM104443_04305	COG0357	Ribosomal RNA small subunit methyltransferase G
DSM104443_04306	COG0445	tRNA wobble uridine modification
DSM104443_04309	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSM104443_04310	COG0706	membrane insertase activity
DSM104443_04311	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSM104443_04312	COG0594	ribonuclease P activity
DSM104443_04313	COG0230	Belongs to the bacterial ribosomal protein bL34 family