locus-tag	class	description
NDA17_000002	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDA17_000008	COG5265	(ABC) transporter
NDA17_000009	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDA17_000024	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NDA17_000031	COG0477	Major facilitator Superfamily
NDA17_000034	COG2205	protein histidine kinase activity
NDA17_000034	COG2198	Histidine kinase
NDA17_000034	COG0784	Response regulator, receiver
NDA17_000038	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDA17_000070	COG1132	(ABC) transporter
NDA17_000103	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDA17_000105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDA17_000110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDA17_000110	COG3321	synthase
NDA17_000110	COG4221	oxidoreductase activity
NDA17_000110	COG0604	alcohol dehydrogenase
NDA17_000121	COG0316	Belongs to the HesB IscA family
NDA17_000126	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDA17_000131	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDA17_000134	COG0513	Belongs to the DEAD box helicase family
NDA17_000138	COG0484	heat shock protein binding
NDA17_000175	COG2319	Wd-40 repeat
NDA17_000182	COG1785	Belongs to the alkaline phosphatase family
NDA17_000183	COG0285	dihydrofolate synthase activity
NDA17_000198	COG1611	Belongs to the LOG family
NDA17_000202	COG0183	Belongs to the thiolase family
NDA17_000204	COG1760	l-serine dehydratase
NDA17_000208	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDA17_000216	COG1104	cysteine desulfurase activity
NDA17_000218	COG1472	Belongs to the glycosyl hydrolase 3 family
NDA17_000224	COG0514	ATP-dependent DNA helicase (RecQ)
NDA17_000250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NDA17_000265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NDA17_000276	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDA17_000281	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDA17_000284	COG0318	PFAM AMP-dependent synthetase and ligase
NDA17_000307	COG1034	ATP synthesis coupled electron transport
NDA17_000316	COG5383	Protein conserved in bacteria
NDA17_000323	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDA17_000328	COG4178	(ABC) transporter
NDA17_000333	COG0484	heat shock protein binding
NDA17_000356	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDA17_000398	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NDA17_000398	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NDA17_000414	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NDA17_000416	COG0017	Asparaginyl-tRNA synthetase
NDA17_000422	COG0784	Response regulator, receiver
NDA17_000422	COG2205	protein histidine kinase activity
NDA17_000430	COG0477	Major facilitator Superfamily
NDA17_000430	COG2814	Major facilitator Superfamily
NDA17_000442	COG0473	3-isopropylmalate dehydrogenase activity
NDA17_000450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NDA17_000455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_000456	COG0387	Pfam Sodium calcium exchanger
NDA17_000473	COG0513	Belongs to the DEAD box helicase family
NDA17_000483	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NDA17_000484	COG0148	phosphopyruvate hydratase activity
NDA17_000491	COG0436	Aminotransferase
NDA17_000499	COG2175	clavaminate synthase activity
NDA17_000505	COG0572	uridine kinase
NDA17_000506	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NDA17_000514	COG0529	Catalyzes the synthesis of activated sulfate
NDA17_000517	COG2814	Major facilitator Superfamily
NDA17_000525	COG2890	protein-(glutamine-N5) methyltransferase activity
NDA17_000526	COG2271	Major facilitator Superfamily
NDA17_000530	COG0438	transferase activity, transferring glycosyl groups
NDA17_000532	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_000533	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDA17_000542	COG1063	alcohol dehydrogenase
NDA17_000546	COG0328	RNA-DNA hybrid ribonuclease activity
NDA17_000582	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NDA17_000610	COG2132	Multicopper oxidase
NDA17_000640	COG0175	sulfate reduction
NDA17_000669	COG0442	prolyl-tRNA aminoacylation
NDA17_000693	COG0205	6-phosphofructokinase activity
NDA17_000701	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NDA17_000716	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDA17_000726	COG0003	Pfam Anion-transporting ATPase
NDA17_000728	COG1621	beta-fructofuranosidase activity
NDA17_000733	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDA17_000760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NDA17_000762	COG0142	geranyltranstransferase activity
NDA17_000764	COG0233	cytoplasmic translational termination
NDA17_000791	COG0006	proline dipeptidase activity
NDA17_000808	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_000817	COG0656	L-ascorbic acid biosynthetic process
NDA17_000825	COG0488	(ABC) transporter
NDA17_000840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDA17_000845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NDA17_000853	COG0316	Belongs to the HesB IscA family
NDA17_000854	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NDA17_000857	COG2072	flavoprotein involved in K transport
NDA17_000858	COG0714	Associated with various cellular activities
NDA17_000859	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDA17_000875	COG0083	homoserine kinase activity
NDA17_000883	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDA17_000892	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_000892	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_000893	COG2814	Major facilitator Superfamily
NDA17_000895	COG1793	dna ligase
NDA17_000903	COG1584	GPR1 FUN34 yaaH family protein
NDA17_000905	COG0488	(ABC) transporter
NDA17_000909	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDA17_000917	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NDA17_000937	COG0513	Belongs to the DEAD box helicase family
NDA17_000939	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDA17_000974	COG0459	protein refolding
NDA17_000980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDA17_000980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDA17_000986	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDA17_001000	COG5398	heme oxygenase
NDA17_001002	COG0514	ATP-dependent DNA helicase (RecQ)
NDA17_001003	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NDA17_001005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDA17_001011	COG3537	Alpha-1,2-mannosidase
NDA17_001033	COG0714	Associated with various cellular activities
NDA17_001035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDA17_001035	COG0519	Catalyzes the synthesis of GMP from XMP
NDA17_001046	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDA17_001051	COG0235	Class ii aldolase
NDA17_001051	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NDA17_001059	COG0477	Major facilitator Superfamily
NDA17_001059	COG2814	Major facilitator Superfamily
NDA17_001070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDA17_001071	COG0477	Major facilitator Superfamily
NDA17_001090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NDA17_001098	COG0515	serine threonine protein kinase
NDA17_001098	COG2815	serine threonine protein kinase
NDA17_001125	COG0617	tRNA 3'-terminal CCA addition
NDA17_001143	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NDA17_001146	COG1960	acyl-CoA dehydrogenase activity
NDA17_001188	COG0833	amino acid
NDA17_001218	COG0009	L-threonylcarbamoyladenylate synthase
NDA17_001235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDA17_001250	COG0833	amino acid
NDA17_001258	COG1252	NADH dehydrogenase
NDA17_001267	COG0017	Asparaginyl-tRNA synthetase
NDA17_001275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDA17_001280	COG4991	sh3 domain protein
NDA17_001280	COG0515	serine threonine protein kinase
NDA17_001280	COG3064	Membrane
NDA17_001292	COG0456	acetyltransferase
NDA17_001301	COG0459	protein refolding
NDA17_001308	COG1183	phosphatidylcholine synthase activity
NDA17_001310	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDA17_001349	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NDA17_001375	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDA17_001389	COG0512	Glutamine amidotransferase of anthranilate synthase
NDA17_001389	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDA17_001391	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDA17_001404	COG0166	Belongs to the GPI family
NDA17_001417	COG0525	valine-tRNA ligase activity
NDA17_001426	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDA17_001442	COG4284	Utp--glucose-1-phosphate uridylyltransferase
NDA17_001445	COG1132	(ABC) transporter
NDA17_001462	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDA17_001471	COG0556	nucleotide-excision repair
NDA17_001475	COG0129	dihydroxy-acid dehydratase activity
NDA17_001486	COG1129	ABC transporter
NDA17_001490	COG2124	cytochrome p450
NDA17_001490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDA17_001491	COG2986	histidine ammonia-lyase
NDA17_001510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDA17_001533	COG0018	arginyl-trna synthetase
NDA17_001546	COG0022	dehydrogenase e1 component
NDA17_001552	COG0833	amino acid
NDA17_001564	COG0443	Heat shock 70 kDa protein
NDA17_001566	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NDA17_001573	COG1119	ATPase activity
NDA17_001575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_001584	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_001588	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NDA17_001596	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NDA17_001598	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_001600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NDA17_001604	COG0459	protein refolding
NDA17_001615	COG2814	Major facilitator Superfamily
NDA17_001615	COG0477	Major facilitator Superfamily
NDA17_001628	COG0028	Belongs to the TPP enzyme family
NDA17_001668	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDA17_001675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NDA17_001688	COG2217	Heavy metal translocating P-type atpase
NDA17_001693	COG0406	alpha-ribazole phosphatase activity
NDA17_001696	COG0477	Major facilitator Superfamily
NDA17_001696	COG2814	Major facilitator Superfamily
NDA17_001699	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_001722	COG0022	dehydrogenase e1 component
NDA17_001722	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDA17_001726	COG0495	leucyl-tRNA aminoacylation
NDA17_001755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDA17_001757	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NDA17_001765	COG0626	cystathionine gamma-synthase activity
NDA17_001770	COG0459	protein refolding
NDA17_001785	COG0183	Belongs to the thiolase family
NDA17_001787	COG0126	phosphoglycerate kinase activity
NDA17_001792	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NDA17_001797	COG0017	Asparaginyl-tRNA synthetase
NDA17_001812	COG0505	Belongs to the CarA family
NDA17_001827	COG0484	heat shock protein binding
NDA17_001831	COG0484	heat shock protein binding
NDA17_001839	COG1366	Belongs to the anti-sigma-factor antagonist family
NDA17_001845	COG0515	serine threonine protein kinase
NDA17_001856	COG1472	Belongs to the glycosyl hydrolase 3 family
NDA17_001869	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NDA17_001879	COG0442	prolyl-tRNA aminoacylation
NDA17_001891	COG0585	pseudouridine synthase activity
NDA17_001897	COG0542	response to heat
NDA17_001965	COG0481	GTPase activity
NDA17_001970	COG1774	PSP1 C-terminal conserved region
NDA17_001972	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDA17_001979	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NDA17_001980	COG0515	serine threonine protein kinase
NDA17_001980	COG2815	serine threonine protein kinase
NDA17_002042	COG0501	Belongs to the peptidase M48B family
NDA17_002043	COG0513	Belongs to the DEAD box helicase family
NDA17_002051	COG0285	dihydrofolate synthase activity
NDA17_002052	COG0484	heat shock protein binding
NDA17_002058	COG0557	exoribonuclease II activity
NDA17_002064	COG0515	serine threonine protein kinase
NDA17_002066	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDA17_002085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDA17_002098	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NDA17_002104	COG1024	Enoyl-CoA hydratase
NDA17_002119	COG3268	Saccharopine dehydrogenase
NDA17_002127	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_002128	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDA17_002133	COG0833	amino acid
NDA17_002138	COG0037	tRNA processing
NDA17_002154	COG1082	Xylose isomerase domain protein TIM barrel
NDA17_002154	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NDA17_002154	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NDA17_002154	COG1082	Xylose isomerase domain protein TIM barrel
NDA17_002160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NDA17_002166	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_002167	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NDA17_002173	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDA17_002175	COG2224	Isocitrate lyase
NDA17_002185	COG0515	serine threonine protein kinase
NDA17_002189	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NDA17_002264	COG3961	Belongs to the TPP enzyme family
NDA17_002274	COG0154	amidase activity
NDA17_002279	COG0417	DNA replication proofreading
NDA17_002300	COG2815	serine threonine protein kinase
NDA17_002300	COG0515	serine threonine protein kinase
NDA17_002307	COG0523	cobalamin synthesis protein
NDA17_002322	COG0545	Peptidyl-prolyl cis-trans isomerase
NDA17_002331	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_002335	COG0657	acetylesterase activity
NDA17_002338	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NDA17_002342	COG1643	Atp-dependent helicase
NDA17_002350	COG3579	cysteine-type endopeptidase activity
NDA17_002360	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NDA17_002373	COG3276	selenocysteine insertion sequence binding
NDA17_002393	COG1132	(ABC) transporter
NDA17_002394	COG0833	amino acid
NDA17_002400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDA17_002409	COG1131	(ABC) transporter
NDA17_002410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NDA17_002426	COG0538	isocitrate dehydrogenase activity
NDA17_002431	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDA17_002433	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDA17_002437	COG0596	Alpha beta hydrolase
NDA17_002457	COG1063	alcohol dehydrogenase
NDA17_002465	COG1132	(ABC) transporter
NDA17_002484	COG0833	amino acid
NDA17_002491	COG0489	protein tyrosine kinase activity
NDA17_002496	COG0626	cystathionine gamma-synthase activity
NDA17_002508	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDA17_002516	COG1960	acyl-CoA dehydrogenase activity
NDA17_002519	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NDA17_002524	COG0515	serine threonine protein kinase
NDA17_002524	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDA17_002541	COG0656	L-ascorbic acid biosynthetic process
NDA17_002544	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_002555	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_002559	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDA17_002565	COG0459	protein refolding
NDA17_002583	COG1472	Belongs to the glycosyl hydrolase 3 family
NDA17_002592	COG0515	serine threonine protein kinase
NDA17_002592	COG2815	serine threonine protein kinase
NDA17_002626	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NDA17_002629	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDA17_002642	COG0183	Belongs to the thiolase family
NDA17_002644	COG2130	NADP-dependent
NDA17_002666	COG1185	polyribonucleotide nucleotidyltransferase activity
NDA17_002669	COG2124	cytochrome p450
NDA17_002673	COG0647	UMP catabolic process
NDA17_002689	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDA17_002689	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDA17_002696	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_002699	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_002710	COG0440	acetolactate synthase activity
NDA17_002716	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDA17_002722	COG4702	Belongs to the UPF0303 family
NDA17_002730	COG1196	nuclear chromosome segregation
NDA17_002734	COG0438	transferase activity, transferring glycosyl groups
NDA17_002749	COG3534	alpha-L-arabinofuranosidase
NDA17_002753	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDA17_002769	COG1213	nucleotidyl transferase
NDA17_002788	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NDA17_002791	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDA17_002793	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDA17_002806	COG1999	signal sequence binding
NDA17_002812	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDA17_002825	COG2271	Major facilitator Superfamily
NDA17_002827	COG0321	lipoyl(octanoyl) transferase activity
NDA17_002840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDA17_002847	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDA17_002859	COG0596	Alpha beta hydrolase
NDA17_002875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDA17_002897	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDA17_002912	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDA17_002946	COG2124	cytochrome p450
NDA17_002956	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NDA17_002969	COG0180	Tryptophanyl-tRNA synthetase
NDA17_002982	COG0515	serine threonine protein kinase
NDA17_002982	COG2815	serine threonine protein kinase
NDA17_003006	COG0081	regulation of translation
NDA17_003051	COG0489	protein tyrosine kinase activity
NDA17_003067	COG2272	Belongs to the type-B carboxylesterase lipase family
NDA17_003070	COG0513	Belongs to the DEAD box helicase family
NDA17_003081	COG2815	serine threonine protein kinase
NDA17_003081	COG0515	serine threonine protein kinase
NDA17_003103	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDA17_003105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDA17_003115	COG0435	Glutathione S-transferase
NDA17_003119	COG4221	oxidoreductase activity
NDA17_003124	COG4285	Biotin-protein ligase, N terminal
NDA17_003129	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NDA17_003143	COG1448	Aminotransferase
NDA17_003147	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDA17_003159	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDA17_003165	COG0564	pseudouridine synthase activity
NDA17_003176	COG0154	amidase activity
NDA17_003179	COG1063	alcohol dehydrogenase
NDA17_003186	COG0415	Belongs to the DNA photolyase family
NDA17_003193	COG2351	hydroxyisourate hydrolase activity
NDA17_003200	COG0149	triose-phosphate isomerase activity
NDA17_003201	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NDA17_003210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NDA17_003227	COG0038	chloride channel
NDA17_003232	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_003232	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_003234	COG1643	Atp-dependent helicase
NDA17_003279	COG0483	inositol monophosphate 1-phosphatase activity
NDA17_003286	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NDA17_003295	COG2937	Belongs to the GPAT DAPAT family
NDA17_003305	COG0423	glycine-tRNA ligase activity
NDA17_003313	COG1643	Atp-dependent helicase
NDA17_003321	COG0784	Response regulator, receiver
NDA17_003321	COG5002	protein histidine kinase activity
NDA17_003329	COG4106	trans-aconitate 2-methyltransferase activity
NDA17_003346	COG0156	8-amino-7-oxononanoate synthase activity
NDA17_003347	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDA17_003350	COG0804	urea catabolic process
NDA17_003365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDA17_003368	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDA17_003368	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDA17_003381	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDA17_003383	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_003390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_003400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NDA17_003403	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_003405	COG0446	pyridine nucleotide-disulphide oxidoreductase
NDA17_003423	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDA17_003424	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDA17_003431	COG0085	RNA polymerase activity
NDA17_003444	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDA17_003445	COG0252	asparaginase activity
NDA17_003450	COG0484	heat shock protein binding
NDA17_003457	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDA17_003489	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDA17_003491	COG0488	(ABC) transporter
NDA17_003499	COG0142	geranyltranstransferase activity
NDA17_003502	COG0484	heat shock protein binding
NDA17_003516	COG5277	cytoskeleton organization
NDA17_003528	COG0045	succinate-CoA ligase (ADP-forming) activity
NDA17_003546	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NDA17_003551	COG0656	L-ascorbic acid biosynthetic process
NDA17_003553	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NDA17_003557	COG1643	Atp-dependent helicase
NDA17_003558	COG0475	glutathione-regulated potassium exporter activity
NDA17_003565	COG0006	proline dipeptidase activity
NDA17_003576	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDA17_003603	COG2815	serine threonine protein kinase
NDA17_003603	COG0515	serine threonine protein kinase
NDA17_003608	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NDA17_003635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NDA17_003636	COG3266	domain, Protein
NDA17_003636	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NDA17_003645	COG2815	serine threonine protein kinase
NDA17_003645	COG0515	serine threonine protein kinase
NDA17_003650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDA17_003650	COG0512	Glutamine amidotransferase of anthranilate synthase
NDA17_003651	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDA17_003660	COG0724	RNA recognition motif
NDA17_003666	COG0571	ribonuclease III activity
NDA17_003667	COG0406	alpha-ribazole phosphatase activity
NDA17_003671	COG0110	maltose O-acetyltransferase activity
NDA17_003682	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_003716	COG1022	Amp-dependent synthetase and ligase
NDA17_003716	COG3320	Male sterility
NDA17_003721	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NDA17_003727	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDA17_003731	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NDA17_003745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NDA17_003746	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDA17_003747	COG2828	Protein conserved in bacteria
NDA17_003759	COG0288	reversible hydration of carbon dioxide
NDA17_003765	COG0494	nUDIX hydrolase
NDA17_003775	COG0071	Belongs to the small heat shock protein (HSP20) family
NDA17_003777	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NDA17_003787	COG1131	(ABC) transporter
NDA17_003787	COG1716	ATPase activity
NDA17_003787	COG0842	Transport permease protein
NDA17_003806	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDA17_003809	COG1185	polyribonucleotide nucleotidyltransferase activity
NDA17_003812	COG0154	amidase activity
NDA17_003816	COG1162	GTPase activity
NDA17_003826	COG1024	Enoyl-CoA hydratase
NDA17_003827	COG1956	GAF domain-containing protein
NDA17_003835	COG0798	PFAM Bile acid sodium symporter
NDA17_003840	COG0515	serine threonine protein kinase
NDA17_003840	COG2815	serine threonine protein kinase
NDA17_003841	COG2223	nitrite transmembrane transporter activity
NDA17_003842	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_003874	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_003893	COG2814	Major facilitator Superfamily
NDA17_003900	COG2252	PERMEase
NDA17_003916	COG0165	Argininosuccinate lyase
NDA17_003922	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDA17_003935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDA17_003965	COG0513	Belongs to the DEAD box helicase family
NDA17_003966	COG0513	Belongs to the DEAD box helicase family
NDA17_003969	COG0300	oxidoreductase activity
NDA17_003985	COG0303	'Molybdopterin
NDA17_003987	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_003994	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_004002	COG2815	serine threonine protein kinase
NDA17_004002	COG0515	serine threonine protein kinase
NDA17_004026	COG1196	nuclear chromosome segregation
NDA17_004035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDA17_004046	COG0363	glucosamine-6-phosphate deaminase activity
NDA17_004053	COG0183	Belongs to the thiolase family
NDA17_004054	COG0406	alpha-ribazole phosphatase activity
NDA17_004070	COG2226	methyltransferase
NDA17_004080	COG4948	Mandelate Racemase Muconate Lactonizing
NDA17_004082	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDA17_004091	COG0513	Belongs to the DEAD box helicase family
NDA17_004095	COG0366	Alpha amylase catalytic
NDA17_004096	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDA17_004103	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_004112	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NDA17_004114	COG0318	PFAM AMP-dependent synthetase and ligase
NDA17_004120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDA17_004125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_004127	COG2226	methyltransferase
NDA17_004169	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NDA17_004170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDA17_004187	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NDA17_004191	COG2815	serine threonine protein kinase
NDA17_004191	COG0515	serine threonine protein kinase
NDA17_004202	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDA17_004205	COG0515	serine threonine protein kinase
NDA17_004212	COG0004	ammonium transporteR
NDA17_004231	COG0515	serine threonine protein kinase
NDA17_004231	COG2815	serine threonine protein kinase
NDA17_004232	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NDA17_004267	COG1612	heme a metabolic process
NDA17_004277	COG0557	exoribonuclease II activity
NDA17_004290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NDA17_004295	COG2271	Major facilitator Superfamily
NDA17_004316	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NDA17_004345	COG2814	Major facilitator Superfamily
NDA17_004348	COG0515	serine threonine protein kinase
NDA17_004350	COG1902	pentaerythritol trinitrate reductase activity
NDA17_004354	COG0670	Belongs to the BI1 family
NDA17_004358	COG0463	Glycosyl transferase, family 2
NDA17_004359	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NDA17_004362	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NDA17_004380	COG0688	phosphatidylethanolamine metabolic process
NDA17_004383	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDA17_004385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NDA17_004388	COG4178	(ABC) transporter
NDA17_004389	COG0515	serine threonine protein kinase
NDA17_004395	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_004396	COG1741	Belongs to the pirin family
NDA17_004398	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDA17_004404	COG0318	PFAM AMP-dependent synthetase and ligase
NDA17_004446	COG0477	Major facilitator Superfamily
NDA17_004455	COG0181	hydroxymethylbilane synthase activity
NDA17_004467	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDA17_004468	COG0527	aspartate kinase activity
NDA17_004468	COG0460	homoserine dehydrogenase
NDA17_004469	COG2072	flavoprotein involved in K transport
NDA17_004480	COG0459	protein refolding
NDA17_004499	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDA17_004505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDA17_004513	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NDA17_004518	COG0203	ribosomal protein L17
NDA17_004535	COG0156	8-amino-7-oxononanoate synthase activity
NDA17_004538	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDA17_004543	COG0367	asparagine synthase
NDA17_004545	COG0072	phenylalanine-tRNA ligase activity
NDA17_004553	COG0604	alcohol dehydrogenase
NDA17_004558	COG1819	glycosyl
NDA17_004562	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_004566	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDA17_004602	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_004603	COG1073	alpha beta
NDA17_004604	COG0833	amino acid
NDA17_004630	COG1819	glycosyl
NDA17_004637	COG0039	L-malate dehydrogenase activity
NDA17_004643	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDA17_004667	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NDA17_004672	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDA17_004675	COG2971	BadF BadG BcrA BcrD
NDA17_004681	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NDA17_004682	COG0156	8-amino-7-oxononanoate synthase activity
NDA17_004686	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NDA17_004713	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NDA17_004725	COG2814	Major facilitator Superfamily
NDA17_004738	COG0513	Belongs to the DEAD box helicase family
NDA17_004744	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDA17_004762	COG1205	dead DEAH box helicase
NDA17_004762	COG1111	helicase
NDA17_004765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_004784	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NDA17_004793	COG2816	NAD+ diphosphatase activity
NDA17_004807	COG0415	Belongs to the DNA photolyase family
NDA17_004808	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDA17_004827	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NDA17_004830	COG1194	a g-specific adenine glycosylase
NDA17_004831	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_004852	COG2814	Major facilitator Superfamily
NDA17_004857	COG2072	flavoprotein involved in K transport
NDA17_004869	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDA17_004885	COG0484	heat shock protein binding
NDA17_004892	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDA17_004913	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDA17_004915	COG1196	nuclear chromosome segregation
NDA17_004920	COG0670	Belongs to the BI1 family
NDA17_004934	COG2030	dehydratase
NDA17_004936	COG0038	chloride channel
NDA17_004939	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDA17_004956	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NDA17_004971	COG2815	serine threonine protein kinase
NDA17_004971	COG0515	serine threonine protein kinase
NDA17_004988	COG0571	ribonuclease III activity
NDA17_004990	COG1132	(ABC) transporter
NDA17_004994	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDA17_005018	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDA17_005035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NDA17_005036	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDA17_005043	COG1131	(ABC) transporter
NDA17_005046	COG0557	exoribonuclease II activity
NDA17_005054	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDA17_005059	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDA17_005087	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDA17_005087	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDA17_005096	COG0833	amino acid
NDA17_005151	COG0698	ribose 5-phosphate isomerase
NDA17_005157	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDA17_005157	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDA17_005168	COG0318	PFAM AMP-dependent synthetase and ligase
NDA17_005171	COG1064	alcohol dehydrogenase
NDA17_005174	COG0101	tRNA pseudouridine synthase activity
NDA17_005175	COG2814	Major facilitator Superfamily
NDA17_005191	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDA17_005196	COG2272	Belongs to the type-B carboxylesterase lipase family
NDA17_005199	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NDA17_005200	COG0408	coproporphyrinogen oxidase activity
NDA17_005209	COG0515	serine threonine protein kinase
NDA17_005211	COG0493	'glutamate synthase
NDA17_005220	COG1643	Atp-dependent helicase
NDA17_005224	COG0237	dephospho-CoA kinase activity
NDA17_005225	COG0724	RNA recognition motif
NDA17_005229	COG0405	Gamma-glutamyltransferase
NDA17_005233	COG0563	adenylate kinase activity
NDA17_005234	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDA17_005241	COG1362	aminopeptidase activity
NDA17_005251	COG0515	serine threonine protein kinase
NDA17_005251	COG2815	serine threonine protein kinase
NDA17_005264	COG0133	tryptophan synthase activity
NDA17_005268	COG0483	inositol monophosphate 1-phosphatase activity
NDA17_005273	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDA17_005283	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NDA17_005294	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDA17_005294	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDA17_005305	COG2363	Small membrane protein
NDA17_005309	COG0328	RNA-DNA hybrid ribonuclease activity
NDA17_005313	COG0616	signal peptide processing
NDA17_005330	COG0156	8-amino-7-oxononanoate synthase activity
NDA17_005346	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDA17_005350	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_005356	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_005369	COG5277	cytoskeleton organization
NDA17_005380	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NDA17_005391	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDA17_005407	COG1643	Atp-dependent helicase
NDA17_005422	COG3265	gluconokinase activity
NDA17_005430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDA17_005461	COG3118	belongs to the thioredoxin family
NDA17_005473	COG0415	Belongs to the DNA photolyase family
NDA17_005491	COG2815	serine threonine protein kinase
NDA17_005491	COG0515	serine threonine protein kinase
NDA17_005493	COG0515	serine threonine protein kinase
NDA17_005493	COG2815	serine threonine protein kinase
NDA17_005503	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDA17_005505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDA17_005510	COG0052	Belongs to the universal ribosomal protein uS2 family
NDA17_005525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NDA17_005536	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_005539	COG0488	(ABC) transporter
NDA17_005543	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_005549	COG2814	Major facilitator Superfamily
NDA17_005549	COG0477	Major facilitator Superfamily
NDA17_005579	COG2264	protein methyltransferase activity
NDA17_005581	COG1063	alcohol dehydrogenase
NDA17_005582	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NDA17_005611	COG1472	Belongs to the glycosyl hydrolase 3 family
NDA17_005626	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDA17_005652	COG0515	serine threonine protein kinase
NDA17_005652	COG2815	serine threonine protein kinase
NDA17_005657	COG0101	tRNA pseudouridine synthase activity
NDA17_005671	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDA17_005675	COG0737	Belongs to the 5'-nucleotidase family
NDA17_005684	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NDA17_005696	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NDA17_005709	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NDA17_005720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NDA17_005722	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDA17_005726	COG0475	glutathione-regulated potassium exporter activity
NDA17_005727	COG0187	DNA topoisomerase II activity
NDA17_005728	COG0706	membrane insertase activity
NDA17_005742	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_005747	COG2267	carboxylic ester hydrolase activity
NDA17_005755	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_005765	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_005772	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NDA17_005779	COG5265	(ABC) transporter
NDA17_005780	COG1085	galactose-1-phosphate uridylyltransferase
NDA17_005784	COG1960	acyl-CoA dehydrogenase activity
NDA17_005808	COG2815	serine threonine protein kinase
NDA17_005808	COG0515	serine threonine protein kinase
NDA17_005816	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NDA17_005840	COG2890	protein-(glutamine-N5) methyltransferase activity
NDA17_005844	COG1222	aaa ATPase
NDA17_005850	COG0405	Gamma-glutamyltransferase
NDA17_005853	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_005856	COG1253	flavin adenine dinucleotide binding
NDA17_005862	COG3118	belongs to the thioredoxin family
NDA17_005873	COG1234	tRNA 3'-trailer cleavage
NDA17_005887	COG0489	protein tyrosine kinase activity
NDA17_005899	COG0484	heat shock protein binding
NDA17_005927	COG0513	Belongs to the DEAD box helicase family
NDA17_005944	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NDA17_005947	COG0482	sulfurtransferase activity
NDA17_005956	COG1132	(ABC) transporter
NDA17_005957	COG2814	Major facilitator Superfamily
NDA17_005959	COG1716	ATPase activity
NDA17_005959	COG0842	Transport permease protein
NDA17_005959	COG1131	(ABC) transporter
NDA17_005967	COG0154	amidase activity
NDA17_005969	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NDA17_005976	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_005987	COG0277	FAD linked oxidase domain protein
NDA17_005992	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDA17_006012	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_006024	COG1473	amidohydrolase
NDA17_006027	COG5441	Belongs to the UPF0261 family
NDA17_006044	COG0105	UTP biosynthetic process
NDA17_006063	COG0088	Forms part of the polypeptide exit tunnel
NDA17_006070	COG0484	heat shock protein binding
NDA17_006079	COG1132	(ABC) transporter
NDA17_006117	COG2124	cytochrome p450
NDA17_006117	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDA17_006119	COG1643	Atp-dependent helicase
NDA17_006123	COG0010	Belongs to the arginase family
NDA17_006141	COG1132	(ABC) transporter
NDA17_006166	COG0534	Mate efflux family protein
NDA17_006187	COG2814	Major facilitator Superfamily
NDA17_006219	COG2272	Belongs to the type-B carboxylesterase lipase family
NDA17_006224	COG3693	PFAM glycoside hydrolase, family 10
NDA17_006230	COG1160	GTP binding
NDA17_006272	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDA17_006275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NDA17_006291	COG0588	phosphoglycerate mutase activity
NDA17_006303	COG0052	Belongs to the universal ribosomal protein uS2 family
NDA17_006304	COG0596	Alpha beta hydrolase
NDA17_006314	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDA17_006332	COG0405	Gamma-glutamyltransferase
NDA17_006340	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NDA17_006344	COG0673	inositol 2-dehydrogenase activity
NDA17_006360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_006365	COG2814	Major facilitator Superfamily
NDA17_006366	COG2815	serine threonine protein kinase
NDA17_006366	COG0515	serine threonine protein kinase
NDA17_006398	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDA17_006401	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDA17_006402	COG0124	histidyl-tRNA synthetase
NDA17_006404	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDA17_006408	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDA17_006444	COG0484	heat shock protein binding
NDA17_006454	COG0537	adenosine 5'-monophosphoramidase activity
NDA17_006460	COG1643	Atp-dependent helicase
NDA17_006466	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDA17_006466	COG0515	serine threonine protein kinase
NDA17_006481	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NDA17_006485	COG0571	ribonuclease III activity
NDA17_006491	COG3239	Fatty acid desaturase
NDA17_006498	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDA17_006523	COG0435	Glutathione S-transferase
NDA17_006535	COG2271	Major facilitator Superfamily
NDA17_006537	COG2267	carboxylic ester hydrolase activity
NDA17_006554	COG0612	Peptidase, M16
NDA17_006574	COG0481	GTPase activity
NDA17_006601	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_006615	COG0138	bifunctional purine biosynthesis protein purh
NDA17_006633	COG0656	L-ascorbic acid biosynthetic process
NDA17_006638	COG0513	Belongs to the DEAD box helicase family
NDA17_006656	COG0477	Major facilitator Superfamily
NDA17_006658	COG0477	Major facilitator Superfamily
NDA17_006677	COG0667	Aldo Keto reductase
NDA17_006682	COG0318	PFAM AMP-dependent synthetase and ligase
NDA17_006687	COG0047	phosphoribosylformylglycinamidine synthase activity
NDA17_006687	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDA17_006690	COG0671	phosphoesterase, PA-phosphatase related
NDA17_006691	COG1716	ATPase activity
NDA17_006691	COG0842	Transport permease protein
NDA17_006691	COG1131	(ABC) transporter
NDA17_006698	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDA17_006698	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDA17_006710	COG0659	secondary active sulfate transmembrane transporter activity
NDA17_006722	COG3871	stress protein (general stress protein 26)
NDA17_006723	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDA17_006759	COG2264	protein methyltransferase activity
NDA17_006764	COG0025	NhaP-type Na H and K H
NDA17_006772	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDA17_006793	COG0417	DNA replication proofreading
NDA17_006803	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDA17_006803	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NDA17_006820	COG0492	ferredoxin-NADP+ reductase activity
NDA17_006831	COG0443	Heat shock 70 kDa protein
NDA17_006855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDA17_006856	COG0484	heat shock protein binding
NDA17_006884	COG0575	Belongs to the CDS family
NDA17_006909	COG1025	Belongs to the peptidase M16 family
NDA17_006910	COG2272	Belongs to the type-B carboxylesterase lipase family
NDA17_006913	COG1505	serine-type exopeptidase activity
NDA17_006915	COG0351	phosphomethylpyrimidine kinase
NDA17_006915	COG0352	thiamine-phosphate diphosphorylase activity
NDA17_006915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NDA17_006919	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_006927	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NDA17_006934	COG0436	Aminotransferase
NDA17_006936	COG0504	CTP synthase activity
NDA17_006952	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDA17_006960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDA17_006966	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NDA17_006974	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDA17_006991	COG3397	chitin binding
NDA17_007002	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDA17_007007	COG0515	serine threonine protein kinase
NDA17_007010	COG3119	arylsulfatase activity
NDA17_007015	COG0745	RESPONSE REGULATOR receiver
NDA17_007025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NDA17_007066	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDA17_007087	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDA17_007089	COG0626	cystathionine gamma-synthase activity
NDA17_007096	COG2272	Belongs to the type-B carboxylesterase lipase family
NDA17_007101	COG0515	serine threonine protein kinase
NDA17_007105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDA17_007124	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NDA17_007127	COG2267	carboxylic ester hydrolase activity
NDA17_007131	COG1012	belongs to the aldehyde dehydrogenase family
NDA17_007140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NDA17_007144	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDA17_007157	COG0167	dihydroorotate dehydrogenase activity
NDA17_007158	COG0477	Major facilitator Superfamily
NDA17_007159	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NDA17_007160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDA17_007162	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDA17_007165	COG0436	Aminotransferase
NDA17_007169	COG0384	phenazine biosynthesis protein PhzF
NDA17_007185	COG0724	RNA recognition motif
NDA17_007189	COG0179	Fumarylacetoacetate (FAA) hydrolase
NDA17_007199	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDA17_007199	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NDA17_007210	COG0513	Belongs to the DEAD box helicase family
NDA17_007217	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NDA17_007234	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDA17_007263	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NDA17_007266	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDA17_007290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NDA17_007306	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDA17_007314	COG4221	oxidoreductase activity
NDA17_007318	COG0784	Response regulator, receiver
NDA17_007318	COG2205	protein histidine kinase activity
NDA17_007335	COG1061	Type III restriction enzyme res subunit
NDA17_007340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDA17_007340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDA17_007350	COG4221	oxidoreductase activity
NDA17_007357	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NDA17_007363	COG1132	(ABC) transporter
NDA17_007368	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDA17_007368	COG2124	cytochrome p450
NDA17_007369	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDA17_007387	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDA17_007401	COG4770	biotin carboxylase activity
NDA17_007434	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_007447	COG0515	serine threonine protein kinase
NDA17_007447	COG2815	serine threonine protein kinase
NDA17_007453	COG0473	3-isopropylmalate dehydrogenase activity
NDA17_007470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NDA17_007471	COG1028	Short-chain dehydrogenase reductase Sdr
NDA17_007472	COG0822	iron-sulfur transferase activity
NDA17_007476	COG4221	oxidoreductase activity
NDA17_007479	COG0204	Acyl-transferase
NDA17_007481	COG0443	Heat shock 70 kDa protein
NDA17_007483	COG0833	amino acid
NDA17_007486	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NDA17_007497	COG0436	Aminotransferase
NDA17_007520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDA17_007554	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDA17_007554	COG0519	Catalyzes the synthesis of GMP from XMP
NDA17_007555	COG0513	Belongs to the DEAD box helicase family
NDA17_007565	COG1132	(ABC) transporter
NDA17_007567	COG2897	thiosulfate sulfurtransferase activity
NDA17_007571	COG0277	FAD linked oxidase domain protein
NDA17_007573	COG4948	Mandelate Racemase Muconate Lactonizing
NDA17_007575	COG2815	serine threonine protein kinase
NDA17_007575	COG0515	serine threonine protein kinase
NDA17_007578	COG0109	protoheme IX farnesyltransferase activity
NDA17_007582	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDA17_007589	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NDA17_007591	COG0105	UTP biosynthetic process
NDA17_007595	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NDA17_007602	COG0515	serine threonine protein kinase
NDA17_007602	COG2815	serine threonine protein kinase
NDA17_007616	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDA17_007622	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDA17_007643	COG1793	dna ligase
NDA17_007660	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NDA17_007660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDA17_007667	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NDA17_007686	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDA17_007686	COG2146	nitrite reductase [NAD(P)H] activity
NDA17_007687	COG0513	Belongs to the DEAD box helicase family
NDA17_007696	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDA17_007729	COG1482	cell wall glycoprotein biosynthetic process
NDA17_007734	COG0484	heat shock protein binding
NDA17_007766	COG0459	protein refolding
NDA17_007768	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NDA17_007778	COG0017	Asparaginyl-tRNA synthetase