locus-tag	class	description
BW732_00005	COG0439	Biotin carboxylase
BW732_00010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BW732_00015	COG0825	malonyl-CoA metabolic process
BW732_00020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BW732_00070	COG1122	ATPase activity
BW732_00080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BW732_00090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BW732_00095	COG0352	thiamine-phosphate diphosphorylase activity
BW732_00100	COG0351	phosphomethylpyrimidine kinase
BW732_00110	COG1957	nucleoside hydrolase
BW732_00115	COG2252	PERMEase
BW732_00120	COG2814	Major facilitator Superfamily
BW732_00130	COG0587	DNA-directed DNA polymerase activity
BW732_00135	COG0205	6-phosphofructokinase activity
BW732_00180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BW732_00185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BW732_00190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BW732_00195	COG0287	Prephenate dehydrogenase
BW732_00205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BW732_00210	COG0077	Prephenate dehydratase
BW732_00215	COG1316	TRANSCRIPTIONal
BW732_00220	COG1307	EDD domain protein, DegV family
BW732_00235	COG0513	Belongs to the DEAD box helicase family
BW732_00245	COG0745	RESPONSE REGULATOR receiver
BW732_00260	COG2391	methyltransferase activity
BW732_00265	COG0446	pyridine nucleotide-disulphide oxidoreductase
BW732_00270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BW732_00275	COG4521	taurine ABC transporter
BW732_00280	COG1116	anion transmembrane transporter activity
BW732_00285	COG4476	Belongs to the UPF0223 family
BW732_00290	COG0483	inositol monophosphate 1-phosphatase activity
BW732_00300	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_00310	COG0481	GTPase activity
BW732_00315	COG0463	Glycosyl transferase, family 2
BW732_00325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BW732_00330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BW732_00335	COG1832	CoA-binding protein
BW732_00340	COG0765	amino acid transport
BW732_00345	COG1126	abc transporter atp-binding protein
BW732_00350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BW732_00360	COG0187	DNA topoisomerase II activity
BW732_00365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BW732_00375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BW732_00385	COG2076	Multidrug Resistance protein
BW732_00390	COG2076	Multidrug Resistance protein
BW732_00395	COG1227	inorganic diphosphatase activity
BW732_00405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW732_00415	COG0564	pseudouridine synthase activity
BW732_00420	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BW732_00425	COG2233	PERMEase
BW732_00430	COG0540	Belongs to the ATCase OTCase family
BW732_00435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BW732_00445	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BW732_00450	COG0543	2 iron, 2 sulfur cluster binding
BW732_00455	COG0167	dihydroorotate dehydrogenase activity
BW732_00460	COG0284	orotidine-5'-phosphate decarboxylase activity
BW732_00465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BW732_00500	COG2801	Transposase and inactivated derivatives
BW732_00515	COG0531	amino acid
BW732_00560	COG1285	pathogenesis
BW732_00580	COG2801	Transposase and inactivated derivatives
BW732_00640	COG2801	Transposase and inactivated derivatives
BW732_00650	COG4974	Belongs to the 'phage' integrase family
BW732_00665	COG0456	acetyltransferase
BW732_00675	COG4974	Belongs to the 'phage' integrase family
BW732_00680	COG1573	uracil-dna glycosylase
BW732_00685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BW732_00695	COG1484	DNA-dependent DNA replication
BW732_00705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BW732_00715	COG3716	PTS system mannose fructose sorbose family IID component
BW732_00720	COG3715	PTS system
BW732_00735	COG2017	converts alpha-aldose to the beta-anomer
BW732_00740	COG0457	Tetratricopeptide repeat
BW732_00765	COG0237	dephospho-CoA kinase activity
BW732_00770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BW732_00775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BW732_00775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BW732_00800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BW732_00825	COG0166	Belongs to the GPI family
BW732_00830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BW732_00835	COG2081	HI0933 family
BW732_00845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BW732_00850	COG0710	3-dehydroquinate dehydratase activity
BW732_00860	COG1368	sulfuric ester hydrolase activity
BW732_00885	COG1181	Belongs to the D-alanine--D-alanine ligase family
BW732_00885	COG2918	glutathione biosynthetic process
BW732_00895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BW732_00900	COG1597	lipid kinase activity
BW732_00905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BW732_00910	COG0154	amidase activity
BW732_00915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BW732_00920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BW732_00925	COG0210	DNA helicase
BW732_00930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BW732_00935	COG0358	DNA primase activity
BW732_00940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BW732_00945	COG1131	(ABC) transporter
BW732_00970	COG0751	glycine-tRNA ligase activity
BW732_00975	COG0752	glycyl-tRNA synthetase alpha subunit
BW732_00980	COG1381	Involved in DNA repair and RecF pathway recombination
BW732_00985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BW732_00990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BW732_00995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BW732_01005	COG1702	phosphate starvation-inducible protein PhoH
BW732_01010	COG1610	YqeY-like protein
BW732_01020	COG0735	belongs to the Fur family
BW732_01025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BW732_01040	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BW732_01045	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BW732_01050	COG4974	Belongs to the 'phage' integrase family
BW732_01060	COG0542	response to heat
BW732_01065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BW732_01070	COG2195	Cleaves the N-terminal amino acid of tripeptides
BW732_01075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BW732_01080	COG2384	SAM-dependent methyltransferase
BW732_01085	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BW732_01090	COG1187	pseudouridine synthase activity
BW732_01095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BW732_01100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BW732_01105	COG4974	Belongs to the 'phage' integrase family
BW732_01115	COG0735	belongs to the Fur family
BW732_01120	COG2996	Protein conserved in bacteria
BW732_01130	COG2814	Major facilitator Superfamily
BW732_01135	COG2814	Major facilitator Superfamily
BW732_01145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BW732_01155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BW732_01165	COG0514	ATP-dependent DNA helicase (RecQ)
BW732_01180	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BW732_01185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BW732_01190	COG0758	DNA mediated transformation
BW732_01195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BW732_01220	COG0640	Transcriptional regulator
BW732_01225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BW732_01230	COG0492	ferredoxin-NADP+ reductase activity
BW732_01235	COG0534	Mate efflux family protein
BW732_01245	COG1131	(ABC) transporter
BW732_01260	COG0006	proline dipeptidase activity
BW732_01270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BW732_01275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BW732_01280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BW732_01285	COG5002	protein histidine kinase activity
BW732_01290	COG0745	RESPONSE REGULATOR receiver
BW732_01295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BW732_01300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BW732_01305	COG0544	peptidyl-prolyl cis-trans isomerase activity
BW732_01315	COG4703	Protein of unknown function (DUF1797)
BW732_01320	COG2084	Dehydrogenase
BW732_01330	COG0438	transferase activity, transferring glycosyl groups
BW732_01335	COG0438	transferase activity, transferring glycosyl groups
BW732_01345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BW732_01360	COG0542	response to heat
BW732_01370	COG1414	Transcriptional regulator
BW732_01375	COG0039	L-malate dehydrogenase activity
BW732_01390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BW732_01395	COG2153	protein acetylation
BW732_01400	COG0628	permease
BW732_01405	COG1253	flavin adenine dinucleotide binding
BW732_01410	COG0456	acetyltransferase
BW732_01420	COG4975	Glucose uptake
BW732_01425	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_01435	COG0335	large ribosomal subunit rRNA binding
BW732_01440	COG0336	Belongs to the RNA methyltransferase TrmD family
BW732_01445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BW732_01450	COG1837	Belongs to the UPF0109 family
BW732_01455	COG0228	four-way junction DNA binding
BW732_01475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BW732_01480	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BW732_01485	COG5002	protein histidine kinase activity
BW732_01490	COG0745	RESPONSE REGULATOR receiver
BW732_01495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BW732_01505	COG0484	heat shock protein binding
BW732_01510	COG0443	Heat shock 70 kDa protein
BW732_01515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BW732_01520	COG1420	regulation of RNA biosynthetic process
BW732_01525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BW732_01530	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_01535	COG0196	riboflavin kinase activity
BW732_01540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BW732_01545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BW732_01550	COG0765	amino acid transport
BW732_01555	COG1363	Peptidase, m42
BW732_01560	COG0673	inositol 2-dehydrogenase activity
BW732_01570	COG0436	Aminotransferase
BW732_01595	COG4895	conserved protein (DUF2196)
BW732_01605	COG0346	lactoylglutathione lyase activity
BW732_01620	COG0463	Glycosyl transferase, family 2
BW732_01635	COG0504	CTP synthase activity
BW732_01670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BW732_01680	COG4841	protein insertion into membrane
BW732_01685	COG0569	domain protein
BW732_01690	COG2197	response regulator
BW732_01695	COG4585	Histidine kinase
BW732_01705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BW732_01715	COG2824	Alkylphosphonate utilization operon protein PhnA
BW732_01740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BW732_01745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BW732_01745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BW732_01750	COG0726	polysaccharide deacetylase
BW732_01760	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BW732_01765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BW732_01770	COG1696	Membrane protein involved in D-alanine export
BW732_01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BW732_01785	COG3557	Belongs to the UPF0374 family
BW732_01790	COG1194	a g-specific adenine glycosylase
BW732_01795	COG2137	regulation of response to DNA damage stimulus
BW732_01825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BW732_01850	COG1216	Glycosyl transferase, family 2
BW732_01850	COG1442	glycosyl transferase family 8
BW732_01860	COG0438	transferase activity, transferring glycosyl groups
BW732_01870	COG0438	transferase activity, transferring glycosyl groups
BW732_01875	COG0110	maltose O-acetyltransferase activity
BW732_01880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BW732_01885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BW732_01895	COG4464	protein tyrosine phosphatase activity
BW732_01900	COG0489	protein tyrosine kinase activity
BW732_01910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BW732_01915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BW732_01920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BW732_01920	COG0463	Glycosyl transferase, family 2
BW732_01925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BW732_01930	COG1682	transport, permease protein
BW732_01935	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BW732_01940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BW732_01945	COG1134	teichoic acid transport
BW732_01950	COG1316	TRANSCRIPTIONal
BW732_01955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BW732_01960	COG1295	ribonuclease BN
BW732_01965	COG0024	Methionine aminopeptidase
BW732_01970	COG0716	FMN binding
BW732_01980	COG2309	aminopeptidase activity
BW732_01985	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BW732_01985	COG0392	lysyltransferase activity
BW732_02005	COG0673	inositol 2-dehydrogenase activity
BW732_02020	COG0735	belongs to the Fur family
BW732_02025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BW732_02030	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BW732_02035	COG1278	Cold shock
BW732_02055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BW732_02060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BW732_02065	COG3442	glutamine amidotransferase
BW732_02075	COG1482	cell wall glycoprotein biosynthetic process
BW732_02085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BW732_02095	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BW732_02100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BW732_02110	COG1461	Dihydroxyacetone kinase
BW732_02115	COG2376	Dihydroxyacetone kinase
BW732_02120	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BW732_02135	COG0222	ribosome binding
BW732_02140	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BW732_02145	COG0081	regulation of translation
BW732_02150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BW732_02160	COG0395	ABC-type sugar transport system, permease component
BW732_02165	COG1175	transmembrane transport
BW732_02175	COG1609	Transcriptional regulator
BW732_02190	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BW732_02195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BW732_02210	COG2801	Transposase and inactivated derivatives
BW732_02220	COG1278	Cold shock
BW732_02225	COG0363	glucosamine-6-phosphate deaminase activity
BW732_02230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BW732_02235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BW732_02240	COG0302	gtp cyclohydrolase
BW732_02245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BW732_02255	COG0512	Glutamine amidotransferase of anthranilate synthase
BW732_02265	COG1136	(ABC) transporter
BW732_02275	COG2814	Major facilitator Superfamily
BW732_02290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BW732_02295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BW732_02310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BW732_02320	COG0789	Transcriptional regulator
BW732_02330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BW732_02335	COG0584	glycerophosphoryl diester phosphodiesterase
BW732_02345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BW732_02350	COG1940	carbohydrate kinase activity
BW732_02360	COG0705	Rhomboid family
BW732_02360	COG0457	Tetratricopeptide repeat
BW732_02365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BW732_02375	COG1744	ABC transporter substrate-binding protein PnrA-like
BW732_02385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BW732_02390	COG0768	penicillin binding
BW732_02395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BW732_02405	COG0656	L-ascorbic acid biosynthetic process
BW732_02415	COG1129	ABC transporter
BW732_02455	COG2233	PERMEase
BW732_02465	COG2151	metal-sulfur cluster biosynthetic enzyme
BW732_02470	COG5290	Psort location Cytoplasmic, score
BW732_02490	COG2151	metal-sulfur cluster biosynthetic enzyme
BW732_02515	COG0442	prolyl-tRNA aminoacylation
BW732_02520	COG0750	zinc metalloprotease
BW732_02525	COG4589	Belongs to the CDS family
BW732_02530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BW732_02535	COG0233	cytoplasmic translational termination
BW732_02540	COG0528	UMP kinase activity
BW732_02545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BW732_02550	COG0052	Belongs to the universal ribosomal protein uS2 family
BW732_02555	COG0406	alpha-ribazole phosphatase activity
BW732_02570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BW732_02585	COG2190	(PTS) system
BW732_02585	COG1263	PTS System
BW732_02585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_02590	COG1968	undecaprenyl-diphosphatase activity
BW732_02595	COG2217	Heavy metal translocating P-type atpase
BW732_02600	COG0268	Binds directly to 16S ribosomal RNA
BW732_02605	COG1466	dna polymerase III delta subunit
BW732_02610	COG2333	competence protein COMEC
BW732_02610	COG0658	competence protein
BW732_02620	COG1596	polysaccharide export
BW732_02620	COG1555	photosystem II stabilization
BW732_02625	COG3480	Lon protease (S16) C-terminal proteolytic domain
BW732_02630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BW732_02635	COG0742	ribosomal rna small subunit methyltransferase
BW732_02640	COG4471	UPF0298 protein
BW732_02655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BW732_02660	COG0772	Belongs to the SEDS family
BW732_02665	COG4838	Belongs to the UPF0358 family
BW732_02690	COG2226	methyltransferase
BW732_02695	COG0799	negative regulation of ribosome biogenesis
BW732_02700	COG1713	HD superfamily hydrolase involved in NAD metabolism
BW732_02705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BW732_02710	COG1534	Rna-binding protein
BW732_02715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BW732_02735	COG0280	phosphate acetyltransferase
BW732_02770	COG0583	DNA-binding transcription factor activity
BW732_02775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BW732_02780	COG0151	Belongs to the GarS family
BW732_02785	COG0138	bifunctional purine biosynthesis protein purh
BW732_02790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BW732_02805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BW732_02810	COG0047	phosphoribosylformylglycinamidine synthase activity
BW732_02815	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BW732_02820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BW732_02825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BW732_02830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BW732_02835	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BW732_02840	COG1070	Carbohydrate kinase
BW732_02860	COG3414	Phosphotransferase system galactitol-specific IIB component
BW732_02865	COG3775	system Galactitol-specific IIC component
BW732_02875	COG3711	transcriptional antiterminator
BW732_02875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BW732_02915	COG1196	nuclear chromosome segregation
BW732_02915	COG0739	heme binding
BW732_02915	COG0741	lytic transglycosylase activity
BW732_02920	COG0704	Plays a role in the regulation of phosphate uptake
BW732_02925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BW732_02930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BW732_02935	COG0581	inorganic phosphate transmembrane transporter activity
BW732_02940	COG0573	inorganic phosphate transmembrane transporter activity
BW732_02945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BW732_02950	COG2177	Part of the ABC transporter FtsEX involved in
BW732_02955	COG2884	Cell division ATP-binding protein ftsE
BW732_02960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BW732_02965	COG0653	protein targeting
BW732_02980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BW732_02985	COG2267	carboxylic ester hydrolase activity
BW732_02995	COG1739	Uncharacterized protein family UPF0029
BW732_03025	COG0517	IMP dehydrogenase activity
BW732_03035	COG0411	ABC transporter
BW732_03045	COG0559	Belongs to the binding-protein-dependent transport system permease family
BW732_03055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BW732_03065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BW732_03075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BW732_03080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BW732_03085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BW732_03090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BW732_03095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BW732_03100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BW732_03105	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BW732_03110	COG0356	it plays a direct role in the translocation of protons across the membrane
BW732_03115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BW732_03125	COG1647	Serine aminopeptidase, S33
BW732_03135	COG1942	4-Oxalocrotonate Tautomerase
BW732_03140	COG0366	Alpha amylase catalytic
BW732_03145	COG0395	ABC-type sugar transport system, permease component
BW732_03155	COG1653	transport
BW732_03175	COG0697	spore germination
BW732_03180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BW732_03185	COG2207	Transcriptional regulator
BW732_03195	COG0693	protein deglycase activity
BW732_03200	COG2378	regulation of single-species biofilm formation
BW732_03205	COG0148	phosphopyruvate hydratase activity
BW732_03210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BW732_03215	COG0149	triose-phosphate isomerase activity
BW732_03220	COG0126	phosphoglycerate kinase activity
BW732_03230	COG2390	Transcriptional regulator
BW732_03235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BW732_03245	COG0740	serine-type endopeptidase activity
BW732_03255	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW732_03260	COG0022	dehydrogenase e1 component
BW732_03265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BW732_03270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BW732_03275	COG3284	Transcriptional regulator
BW732_03280	COG1481	regulation of sporulation
BW732_03290	COG1660	Displays ATPase and GTPase activities
BW732_03300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BW732_03305	COG0556	nucleotide-excision repair
BW732_03315	COG1316	TRANSCRIPTIONal
BW732_03320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BW732_03335	COG2608	mercury ion transmembrane transporter activity
BW732_03345	COG4975	Glucose uptake
BW732_03350	COG1869	D-ribose catabolic process
BW732_03365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BW732_03375	COG2207	Transcriptional regulator
BW732_03405	COG3962	Belongs to the TPP enzyme family
BW732_03410	COG1349	DNA-binding transcription factor activity
BW732_03425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BW732_03430	COG4565	transcriptional regulatory protein
BW732_03435	COG3290	protein histidine kinase activity
BW732_03440	COG0698	ribose 5-phosphate isomerase
BW732_03445	COG2723	6-phospho-beta-galactosidase activity
BW732_03450	COG3711	transcriptional antiterminator
BW732_03455	COG2190	(PTS) system
BW732_03455	COG1263	PTS System
BW732_03455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_03465	COG0737	Belongs to the 5'-nucleotidase family
BW732_03475	COG1309	transcriptional regulator
BW732_03480	COG0393	Putative heavy-metal-binding
BW732_03500	COG5002	protein histidine kinase activity
BW732_03505	COG0745	RESPONSE REGULATOR receiver
BW732_03510	COG0513	Belongs to the DEAD box helicase family
BW732_03520	COG0564	pseudouridine synthase activity
BW732_03525	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BW732_03550	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BW732_03560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW732_03570	COG1105	Belongs to the carbohydrate kinase PfkB family
BW732_03575	COG3684	Belongs to the aldolase LacD family
BW732_03585	COG2222	sugar isomerase
BW732_03630	COG1063	alcohol dehydrogenase
BW732_03645	COG1131	(ABC) transporter
BW732_03655	COG2801	Transposase and inactivated derivatives
BW732_03705	COG2801	Transposase and inactivated derivatives
BW732_03710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BW732_03715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BW732_03735	COG0436	Aminotransferase
BW732_03745	COG4224	UPF0291 protein
BW732_03750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BW732_03755	COG1363	Peptidase, m42
BW732_03760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BW732_03765	COG3425	synthase
BW732_03785	COG0772	Belongs to the SEDS family
BW732_03795	COG0300	oxidoreductase activity
BW732_03800	COG1234	tRNA 3'-trailer cleavage
BW732_03810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BW732_03815	COG1121	(ABC) transporter
BW732_03820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BW732_03825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BW732_03840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BW732_03870	COG1304	FMN binding
BW732_03875	COG0577	efflux transmembrane transporter activity
BW732_03880	COG1136	(ABC) transporter
BW732_03885	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BW732_03890	COG3104	oligopeptide transport
BW732_03895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_03895	COG1263	PTS System
BW732_03900	COG0366	Alpha amylase catalytic
BW732_03905	COG1609	Transcriptional regulator
BW732_03935	COG0076	glutamate decarboxylase activity
BW732_03940	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BW732_03945	COG1511	domain protein
BW732_03950	COG0531	amino acid
BW732_03960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BW732_03970	COG1902	pentaerythritol trinitrate reductase activity
BW732_03980	COG0726	polysaccharide deacetylase
BW732_03985	COG0726	polysaccharide deacetylase
BW732_03990	COG1132	(ABC) transporter
BW732_03995	COG1132	(ABC) transporter
BW732_04090	COG1098	S1 RNA binding domain
BW732_04100	COG0572	uridine kinase
BW732_04115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BW732_04120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BW732_04125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BW732_04130	COG0659	secondary active sulfate transmembrane transporter activity
BW732_04135	COG2323	membrane
BW732_04145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BW732_04150	COG4109	DRTGG domain
BW732_04160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BW732_04165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BW732_04170	COG4720	Psort location CytoplasmicMembrane, score
BW732_04180	COG0419	ATPase involved in DNA repair
BW732_04185	COG0419	ATPase involved in DNA repair
BW732_04190	COG0420	3'-5' exonuclease activity
BW732_04195	COG0204	Acyl-transferase
BW732_04200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BW732_04205	COG2827	Endonuclease containing a URI domain
BW732_04210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BW732_04215	COG0028	Belongs to the TPP enzyme family
BW732_04220	COG1121	(ABC) transporter
BW732_04225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BW732_04230	COG3859	Proton-coupled thiamine transporter YuaJ
BW732_04235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BW732_04240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BW732_04245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BW732_04250	COG1823	symporter activity
BW732_04255	COG1970	mechanosensitive ion channel activity
BW732_04260	COG0612	Peptidase, M16
BW732_04265	COG0612	Peptidase, M16
BW732_04275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BW732_04285	COG0628	permease
BW732_04320	COG3584	3D domain protein
BW732_04320	COG3583	domain protein
BW732_04330	COG1132	(ABC) transporter
BW732_04335	COG1132	(ABC) transporter
BW732_04345	COG1011	Hydrolase
BW732_04350	COG1803	Methylglyoxal synthase
BW732_04355	COG3842	ATPase activity
BW732_04365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BW732_04370	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BW732_04375	COG0084	hydrolase, TatD family'
BW732_04380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW732_04380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW732_04385	COG4493	Belongs to the UPF0637 family
BW732_04395	COG4607	ABC-type enterochelin transport system periplasmic component
BW732_04400	COG4604	ABC transporter, ATP-binding protein
BW732_04405	COG4605	iron ion homeostasis
BW732_04410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BW732_04415	COG5506	Protein of unknown function (DUF1694)
BW732_04420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BW732_04425	COG4466	Protein conserved in bacteria
BW732_04435	COG3688	RNA-binding protein containing a PIN domain
BW732_04440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BW732_04445	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BW732_04450	COG0215	cysteine-tRNA ligase activity
BW732_04455	COG1045	serine acetyltransferase
BW732_04460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BW732_04465	COG4956	integral membrane protein (PIN domain superfamily)
BW732_04475	COG0756	dUTP diphosphatase activity
BW732_04485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BW732_04490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BW732_04500	COG0561	phosphatase activity
BW732_04505	COG2723	6-phospho-beta-galactosidase activity
BW732_04510	COG1263	PTS System
BW732_04510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_04510	COG2190	(PTS) system
BW732_04520	COG0783	Belongs to the Dps family
BW732_04525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BW732_04540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BW732_04545	COG0085	RNA polymerase activity
BW732_04550	COG2813	Specifically methylates the guanine in position
BW732_04555	COG2755	lipolytic protein G-D-S-L family
BW732_04560	COG1607	acyl-coa hydrolase
BW732_04565	COG1072	(Pantothenic acid kinase))
BW732_04570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BW732_04570	COG0519	Catalyzes the synthesis of GMP from XMP
BW732_04580	COG1396	sequence-specific DNA binding
BW732_04630	COG0402	S-adenosylhomocysteine deaminase activity
BW732_04635	COG0402	S-adenosylhomocysteine deaminase activity
BW732_04640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BW732_04645	COG1132	(ABC) transporter
BW732_04650	COG1132	(ABC) transporter
BW732_04655	COG0842	Transport permease protein
BW732_04660	COG1131	(ABC) transporter
BW732_04670	COG1388	LysM domain
BW732_04690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BW732_04695	COG1024	Enoyl-CoA hydratase
BW732_04700	COG1250	3-hydroxyacyl-CoA dehydrogenase
BW732_04710	COG0583	DNA-binding transcription factor activity
BW732_04725	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BW732_04730	COG1518	maintenance of DNA repeat elements
BW732_04735	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BW732_04740	COG2217	Heavy metal translocating P-type atpase
BW732_04755	COG1714	RDD family
BW732_04780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BW732_04800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BW732_04805	COG2390	Transcriptional regulator
BW732_04835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BW732_04850	COG0561	phosphatase activity
BW732_04855	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BW732_04860	COG0280	phosphate acetyltransferase
BW732_04865	COG0802	atpase or kinase
BW732_04890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BW732_04895	COG0038	chloride channel
BW732_04900	COG1473	amidohydrolase
BW732_04905	COG2801	Transposase and inactivated derivatives
BW732_04955	COG2207	Transcriptional regulator
BW732_04955	COG4753	response regulator
BW732_04980	COG2801	Transposase and inactivated derivatives
BW732_04990	COG0604	alcohol dehydrogenase
BW732_05005	COG1176	ABC-type spermidine putrescine transport system, permease component I
BW732_05010	COG1177	transmembrane transport
BW732_05015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BW732_05025	COG1874	Beta-galactosidase
BW732_05035	COG4946	Tricorn protease homolog
BW732_05035	COG0823	Involved in the tonB-independent uptake of proteins
BW732_05035	COG1506	peptidase
BW732_05040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BW732_05045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BW732_05050	COG4991	sh3 domain protein
BW732_05050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BW732_05050	COG3103	Sh3 type 3 domain protein
BW732_05055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BW732_05075	COG1490	D-aminoacyl-tRNA deacylase activity
BW732_05080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BW732_05085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BW732_05090	COG2264	protein methyltransferase activity
BW732_05105	COG4716	Myosin-crossreactive antigen
BW732_05115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BW732_05145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BW732_05150	COG0827	DNA restriction-modification system
BW732_05180	COG1459	type II secretion system
BW732_05185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BW732_05190	COG0217	transcriptional regulatory protein
BW732_05225	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BW732_05230	COG4988	ABC transporter
BW732_05235	COG1294	oxidase, subunit
BW732_05240	COG1271	oxidase subunit
BW732_05245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BW732_05260	COG3428	Bacterial PH domain
BW732_05265	COG3402	PFAM membrane-flanked domain
BW732_05270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BW732_05285	COG4948	Mandelate Racemase Muconate Lactonizing
BW732_05290	COG0596	Alpha beta hydrolase
BW732_05295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BW732_05300	COG1169	isochorismate synthase
BW732_05305	COG0318	PFAM AMP-dependent synthetase and ligase
BW732_05320	COG1937	Protein conserved in bacteria
BW732_05325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BW732_05330	COG0446	pyridine nucleotide-disulphide oxidoreductase
BW732_05350	COG0778	Nitroreductase
BW732_05375	COG1250	3-hydroxyacyl-CoA dehydrogenase
BW732_05410	COG3973	AAA domain
BW732_05430	COG3764	Sortase (surface protein transpeptidase)
BW732_05545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BW732_05555	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW732_05560	COG4869	propanediol catabolic process
BW732_05565	COG1454	alcohol dehydrogenase
BW732_05565	COG1012	belongs to the aldehyde dehydrogenase family
BW732_05570	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW732_05590	COG4820	ethanolamine utilization protein (EutJ)
BW732_05610	COG4810	utilization protein
BW732_05615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BW732_05620	COG1882	Formate acetyltransferase
BW732_05625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BW732_05630	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW732_05635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW732_05650	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BW732_05655	COG4978	Transcriptional regulator
BW732_05655	COG0789	Transcriptional regulator
BW732_05665	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
BW732_05670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BW732_05675	COG0446	pyridine nucleotide-disulphide oxidoreductase
BW732_05680	COG0431	NADPH-dependent FMN reductase
BW732_05685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BW732_05705	COG2814	Major facilitator Superfamily
BW732_05715	COG2514	catechol 2,3-dioxygenase activity
BW732_05720	COG4690	dipeptidase activity
BW732_05735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BW732_05740	COG0351	phosphomethylpyrimidine kinase
BW732_05750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BW732_05760	COG2801	Transposase and inactivated derivatives
BW732_05770	COG4974	Belongs to the 'phage' integrase family
BW732_05895	COG0582	viral genome integration into host DNA
BW732_05900	COG0582	viral genome integration into host DNA
BW732_05975	COG4974	Belongs to the 'phage' integrase family
BW732_05980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BW732_05985	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BW732_06000	COG1122	ATPase activity
BW732_06005	COG1122	ATPase activity
BW732_06010	COG0203	ribosomal protein L17
BW732_06015	COG0202	RNA polymerase activity
BW732_06020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BW732_06025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BW732_06030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BW732_06035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BW732_06040	COG0563	adenylate kinase activity
BW732_06050	COG0200	Binds to the 23S rRNA
BW732_06055	COG1841	ribosomal large subunit assembly
BW732_06060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BW732_06065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BW732_06070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BW732_06075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BW732_06080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BW732_06085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BW732_06090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BW732_06095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BW732_06100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BW732_06105	COG0255	Belongs to the universal ribosomal protein uL29 family
BW732_06110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BW732_06115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BW732_06120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BW732_06125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BW732_06130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BW732_06135	COG0089	rRNA binding
BW732_06140	COG0088	Forms part of the polypeptide exit tunnel
BW732_06145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BW732_06150	COG0051	transcription antitermination factor activity, RNA binding
BW732_06155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BW732_06160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BW732_06165	COG0049	tRNA binding
BW732_06170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BW732_06175	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BW732_06180	COG0588	phosphoglycerate mutase activity
BW732_06185	COG1114	Component of the transport system for branched-chain amino acids
BW732_06345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BW732_06350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BW732_06365	COG0012	GTP binding
BW732_06370	COG4481	Protein conserved in bacteria
BW732_06375	COG1475	DNA binding
BW732_06380	COG1192	Involved in chromosome partitioning
BW732_06385	COG0357	Ribosomal RNA small subunit methyltransferase G
BW732_06390	COG2140	Oxalate decarboxylase
BW732_06400	COG0445	tRNA wobble uridine modification
BW732_06405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BW732_06415	COG0706	membrane insertase activity
BW732_06420	COG0594	ribonuclease P activity
BW732_06425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BW732_06430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BW732_06435	COG0592	DNA-directed DNA polymerase activity
BW732_06445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BW732_06450	COG0187	DNA topoisomerase II activity
BW732_06470	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_06490	COG0360	Binds together with S18 to 16S ribosomal RNA
BW732_06495	COG0629	single-stranded DNA binding
BW732_06505	COG0359	binds to the 23S rRNA
BW732_06510	COG0305	Participates in initiation and elongation during chromosome replication
BW732_06515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BW732_06525	COG0488	(ABC) transporter
BW732_06530	COG0142	geranyltranstransferase activity
BW732_06545	COG4939	FMN-binding domain protein
BW732_06565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BW732_06575	COG1744	ABC transporter substrate-binding protein PnrA-like
BW732_06595	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BW732_06600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BW732_06615	COG3655	Transcriptional regulator
BW732_06635	COG0519	Catalyzes the synthesis of GMP from XMP
BW732_06670	COG3279	Response regulator of the LytR AlgR family
BW732_06680	COG3328	transposase activity
BW732_06700	COG0463	Glycosyl transferase, family 2
BW732_06705	COG0367	asparagine synthase
BW732_06715	COG1794	racemase activity, acting on amino acids and derivatives
BW732_06725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BW732_06730	COG0477	Major facilitator Superfamily
BW732_06740	COG1242	4 iron, 4 sulfur cluster binding
BW732_06745	COG0671	phosphoesterase, PA-phosphatase related
BW732_06760	COG1705	Flagellar rod assembly protein muramidase FlgJ
BW732_06760	COG1388	LysM domain
BW732_06765	COG0495	leucyl-tRNA aminoacylation
BW732_06770	COG2244	polysaccharide biosynthetic process
BW732_06775	COG1187	pseudouridine synthase activity
BW732_06780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW732_06790	COG1126	abc transporter atp-binding protein
BW732_06815	COG0039	L-malate dehydrogenase activity
BW732_06820	COG0193	aminoacyl-tRNA hydrolase activity
BW732_06825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BW732_06830	COG2244	polysaccharide biosynthetic process
BW732_06835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BW732_06845	COG1098	S1 RNA binding domain
BW732_06850	COG0037	tRNA processing
BW732_06865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BW732_06870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BW732_06875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BW732_06925	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BW732_06930	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BW732_06945	COG2235	arginine
BW732_06950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BW732_06955	COG0549	Belongs to the carbamate kinase family
BW732_06965	COG1288	antiporter activity
BW732_06970	COG0018	arginyl-trna synthetase
BW732_06980	COG0542	response to heat
BW732_07005	COG4684	Psort location CytoplasmicMembrane, score
BW732_07010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BW732_07025	COG1692	metallophosphoesterase
BW732_07040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BW732_07045	COG0424	maF-like protein
BW732_07050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW732_07055	COG0561	phosphatase activity
BW732_07060	COG1609	Transcriptional regulator
BW732_07085	COG0789	Transcriptional regulator
BW732_07085	COG4978	Transcriptional regulator
BW732_07090	COG2801	Transposase and inactivated derivatives
BW732_07110	COG2255	four-way junction helicase activity
BW732_07135	COG1960	acyl-CoA dehydrogenase activity
BW732_07140	COG0583	DNA-binding transcription factor activity
BW732_07145	COG0183	Belongs to the thiolase family
BW732_07150	COG1250	3-hydroxyacyl-CoA dehydrogenase
BW732_07155	COG1024	Enoyl-CoA hydratase
BW732_07160	COG0427	acetyl-CoA hydrolase
BW732_07170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BW732_07175	COG0343	queuine tRNA-ribosyltransferase activity
BW732_07185	COG1073	alpha beta
BW732_07190	COG1012	belongs to the aldehyde dehydrogenase family
BW732_07190	COG1454	alcohol dehydrogenase
BW732_07195	COG1792	Involved in formation and maintenance of cell shape
BW732_07210	COG1695	Transcriptional regulator
BW732_07220	COG1929	Belongs to the glycerate kinase type-1 family
BW732_07235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BW732_07240	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BW732_07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BW732_07265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_07265	COG1263	PTS System
BW732_07270	COG1486	melibiose metabolic process
BW732_07275	COG1737	Transcriptional regulator
BW732_07295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BW732_07305	COG0564	pseudouridine synthase activity
BW732_07310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BW732_07315	COG3679	Belongs to the UPF0342 family
BW732_07320	COG0420	3'-5' exonuclease activity
BW732_07340	COG3764	Sortase (surface protein transpeptidase)
BW732_07350	COG1181	Belongs to the D-alanine--D-alanine ligase family
BW732_07355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BW732_07365	COG0736	holo-[acyl-carrier-protein] synthase activity
BW732_07380	COG1561	YicC-like family, N-terminal region
BW732_07385	COG0194	GDP metabolic process
BW732_07390	COG1758	RNA polymerase activity
BW732_07395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BW732_07400	COG0242	peptide deformylase activity
BW732_07405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BW732_07410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BW732_07410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BW732_07420	COG0515	serine threonine protein kinase
BW732_07420	COG2815	serine threonine protein kinase
BW732_07425	COG1162	GTPase activity
BW732_07430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BW732_07435	COG1564	THIamine pyrophosphokinase
BW732_07445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BW732_07450	COG1302	Protein conserved in bacteria
BW732_07455	COG1461	Dihydroxyacetone kinase
BW732_07460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BW732_07465	COG0416	fatty acid biosynthetic process
BW732_07470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BW732_07480	COG4608	Belongs to the ABC transporter superfamily
BW732_07485	COG0601	transmembrane transport
BW732_07490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BW732_07495	COG0747	negative chemotaxis
BW732_07505	COG0747	negative chemotaxis
BW732_07510	COG0571	ribonuclease III activity
BW732_07515	COG1196	nuclear chromosome segregation
BW732_07520	COG0561	phosphatase activity
BW732_07525	COG0552	protein localization to endoplasmic reticulum
BW732_07530	COG1349	DNA-binding transcription factor activity
BW732_07535	COG1105	Belongs to the carbohydrate kinase PfkB family
BW732_07540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BW732_07540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BW732_07540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BW732_07545	COG1447	Phosphotransferase system cellobiose-specific component IIA
BW732_07550	COG1181	Belongs to the D-alanine--D-alanine ligase family
BW732_07550	COG2918	glutathione biosynthetic process
BW732_07555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BW732_07560	COG4980	gas vesicle protein
BW732_07565	COG0537	adenosine 5'-monophosphoramidase activity
BW732_07570	COG1131	(ABC) transporter
BW732_07575	COG4473	ABC transporter
BW732_07600	COG5584	Small secreted protein
BW732_07605	COG1363	Peptidase, m42
BW732_07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BW732_07620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW732_07625	COG4472	Bacterial protein of unknown function (DUF965)
BW732_07630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BW732_07635	COG3906	Belongs to the UPF0473 family
BW732_07655	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BW732_07670	COG1193	negative regulation of DNA recombination
BW732_07675	COG3118	belongs to the thioredoxin family
BW732_07715	COG4152	abc transporter atp-binding protein
BW732_07720	COG1668	transmembrane transport
BW732_07730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BW732_07740	COG0242	peptide deformylase activity
BW732_07745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BW732_07750	COG1185	polyribonucleotide nucleotidyltransferase activity
BW732_07765	COG3639	organic phosphonate transmembrane transporter activity
BW732_07780	COG1959	2 iron, 2 sulfur cluster binding
BW732_07790	COG2376	Dihydroxyacetone kinase
BW732_07795	COG1461	Dihydroxyacetone kinase
BW732_07800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BW732_07820	COG3493	citrate carrier protein
BW732_07825	COG3290	protein histidine kinase activity
BW732_07830	COG4565	transcriptional regulatory protein
BW732_07850	COG2807	transmembrane transport
BW732_07855	COG1953	Uracil, thiamine, allantoin
BW732_07860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BW732_07870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BW732_07875	COG3257	ureidoglycine aminohydrolase activity
BW732_07880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BW732_07890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BW732_07910	COG2508	Transcriptional regulator
BW732_07915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BW732_07920	COG0459	protein refolding
BW732_07925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BW732_07935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BW732_07940	COG0488	(ABC) transporter
BW732_07945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BW732_07955	COG1164	Oligoendopeptidase f
BW732_07970	COG2357	RelA SpoT domain protein
BW732_07975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BW732_07980	COG0564	pseudouridine synthase activity
BW732_07985	COG2239	Acts as a magnesium transporter
BW732_08000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BW732_08005	COG0406	alpha-ribazole phosphatase activity
BW732_08010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BW732_08015	COG1597	lipid kinase activity
BW732_08025	COG0475	glutathione-regulated potassium exporter activity
BW732_08050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BW732_08055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BW732_08060	COG0250	Participates in transcription elongation, termination and antitermination
BW732_08075	COG1760	l-serine dehydratase
BW732_08080	COG1760	l-serine dehydratase
BW732_08085	COG1058	Belongs to the CinA family
BW732_08085	COG1546	Belongs to the CinA family
BW732_08090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BW732_08095	COG1418	mRNA catabolic process
BW732_08100	COG2207	Transcriptional regulator
BW732_08100	COG1917	Cupin 2, conserved barrel domain protein
BW732_08120	COG0673	inositol 2-dehydrogenase activity
BW732_08125	COG3830	Belongs to the UPF0237 family
BW732_08130	COG2848	UPF0210 protein
BW732_08145	COG0446	pyridine nucleotide-disulphide oxidoreductase
BW732_08165	COG3639	organic phosphonate transmembrane transporter activity
BW732_08180	COG3626	phosphonate metabolism
BW732_08185	COG3627	carbon phosphorus lyase activity
BW732_08190	COG4107	phosphonate C-P lyase system protein PhnK
BW732_08195	COG3454	Phosphonate metabolism
BW732_08200	COG4778	phosphonate C-P lyase system protein PhnL
BW732_08205	COG0613	PHP domain protein
BW732_08215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BW732_08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_08225	COG1263	PTS System
BW732_08225	COG2190	(PTS) system
BW732_08235	COG1609	Transcriptional regulator
BW732_08240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BW732_08245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BW732_08250	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BW732_08255	COG1609	Transcriptional regulator
BW732_08265	COG0436	Aminotransferase
BW732_08270	COG1126	abc transporter atp-binding protein
BW732_08275	COG0765	amino acid transport
BW732_08280	COG1136	(ABC) transporter
BW732_08285	COG1136	(ABC) transporter
BW732_08285	COG0577	efflux transmembrane transporter activity
BW732_08290	COG2195	Cleaves the N-terminal amino acid of tripeptides
BW732_08295	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_08300	COG1053	succinate dehydrogenase
BW732_08315	COG1621	beta-fructofuranosidase activity
BW732_08325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BW732_08325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BW732_08330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BW732_08330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_08340	COG3715	PTS system
BW732_08345	COG3716	PTS system mannose fructose sorbose family IID component
BW732_08355	COG1737	Transcriptional regulator
BW732_08360	COG1486	melibiose metabolic process
BW732_08370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BW732_08370	COG0574	Belongs to the PEP-utilizing enzyme family
BW732_08375	COG0517	IMP dehydrogenase activity
BW732_08380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BW732_08395	COG2801	Transposase and inactivated derivatives
BW732_08415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_08415	COG1263	PTS System
BW732_08430	COG2210	Belongs to the sulfur carrier protein TusA family
BW732_08435	COG0745	RESPONSE REGULATOR receiver
BW732_08440	COG2205	protein histidine kinase activity
BW732_08445	COG1136	(ABC) transporter
BW732_08450	COG0577	efflux transmembrane transporter activity
BW732_08455	COG1764	response to oxidative stress
BW732_08475	COG1914	H( )-stimulated, divalent metal cation uptake system
BW732_08490	COG1979	alcohol dehydrogenase
BW732_08495	COG1349	DNA-binding transcription factor activity
BW732_08500	COG1012	belongs to the aldehyde dehydrogenase family
BW732_08510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BW732_08515	COG1082	Xylose isomerase domain protein TIM barrel
BW732_08520	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BW732_08525	COG0673	inositol 2-dehydrogenase activity
BW732_08535	COG0642	Histidine kinase
BW732_08540	COG0745	RESPONSE REGULATOR receiver
BW732_08545	COG1136	(ABC) transporter
BW732_08570	COG1363	Peptidase, m42
BW732_08575	COG1234	tRNA 3'-trailer cleavage
BW732_08580	COG0095	Lipoate-protein ligase
BW732_08585	COG0180	Tryptophanyl-tRNA synthetase
BW732_08590	COG1393	Belongs to the ArsC family
BW732_08595	COG4862	establishment of competence for transformation
BW732_08625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BW732_08630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BW732_08635	COG1780	Probably involved in ribonucleotide reductase function
BW732_08640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BW732_08650	COG1918	ferrous iron import across plasma membrane
BW732_08650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BW732_08655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BW732_08675	COG4209	transmembrane transport
BW732_08680	COG0395	ABC-type sugar transport system, permease component
BW732_08705	COG1472	Belongs to the glycosyl hydrolase 3 family
BW732_08710	COG3459	Glycosyltransferase 36 associated
BW732_08720	COG0745	RESPONSE REGULATOR receiver
BW732_08725	COG5002	protein histidine kinase activity
BW732_08735	COG4853	Protein conserved in bacteria
BW732_08740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BW732_08750	COG1136	(ABC) transporter
BW732_08770	COG4129	membrane
BW732_08780	COG1876	peptidase activity
BW732_08785	COG1705	Flagellar rod assembly protein muramidase FlgJ
BW732_08810	COG2183	response to ionizing radiation
BW732_08825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BW732_08835	COG3595	metallopeptidase activity
BW732_08840	COG1983	PspC domain protein
BW732_08845	COG1950	PFAM Membrane protein of
BW732_08850	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BW732_08855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BW732_08860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BW732_08865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BW732_08875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BW732_08885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BW732_08895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BW732_08900	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BW732_08905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BW732_08910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BW732_08915	COG3870	Protein conserved in bacteria
BW732_08920	COG0470	DNA polymerase III
BW732_08925	COG1774	PSP1 C-terminal conserved region
BW732_08930	COG4467	Involved in initiation control of chromosome replication
BW732_08945	COG3942	CHAP domain
BW732_08945	COG1705	Flagellar rod assembly protein muramidase FlgJ
BW732_08950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BW732_08955	COG2233	PERMEase
BW732_08960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BW732_08970	COG4989	oxidoreductase activity
BW732_08975	COG1131	(ABC) transporter
BW732_08985	COG0516	GMP reductase activity
BW732_08995	COG0561	phosphatase activity
BW732_09000	COG1078	dGTPase activity
BW732_09005	COG0095	Lipoate-protein ligase
BW732_09015	COG3343	RNA polymerase activity
BW732_09025	COG1012	belongs to the aldehyde dehydrogenase family
BW732_09035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BW732_09040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BW732_09045	COG0254	rRNA binding
BW732_09050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BW732_09055	COG1368	sulfuric ester hydrolase activity
BW732_09060	COG0037	tRNA processing
BW732_09065	COG0488	(ABC) transporter
BW732_09070	COG0779	Required for maturation of 30S ribosomal subunits
BW732_09075	COG0195	Participates in both transcription termination and antitermination
BW732_09080	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BW732_09095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BW732_09105	COG0772	Belongs to the SEDS family
BW732_09115	COG2011	ABC-type metal ion transport system permease component
BW732_09120	COG1464	Belongs to the NlpA lipoprotein family
BW732_09130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BW732_09135	COG1801	Protein of unknown function DUF72
BW732_09150	COG0527	aspartate kinase activity
BW732_09155	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BW732_09160	COG1104	cysteine desulfurase activity
BW732_09165	COG0301	tRNA thio-modification
BW732_09195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BW732_09200	COG0492	ferredoxin-NADP+ reductase activity
BW732_09215	COG1132	(ABC) transporter
BW732_09220	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BW732_09225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BW732_09230	COG0525	valine-tRNA ligase activity
BW732_09235	COG0285	dihydrofolate synthase activity
BW732_09240	COG0546	phosphoglycolate phosphatase activity
BW732_09245	COG2003	Belongs to the UPF0758 family
BW732_09250	COG1278	Cold shock
BW732_09255	COG2365	Tyrosine phosphatase family
BW732_09260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BW732_09265	COG0028	Belongs to the TPP enzyme family
BW732_09270	COG3527	Alpha-acetolactate decarboxylase
BW732_09275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BW732_09275	COG2190	(PTS) system
BW732_09275	COG1263	PTS System
BW732_09290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BW732_09300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BW732_09305	COG3316	Transposase and inactivated derivatives
BW732_09320	COG1302	Protein conserved in bacteria
BW732_09325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BW732_09330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BW732_09335	COG1570	exodeoxyribonuclease VII activity
BW732_09340	COG1722	exodeoxyribonuclease VII activity
BW732_09345	COG0142	geranyltranstransferase activity
BW732_09350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BW732_09355	COG0497	DNA recombination
BW732_09370	COG2001	Belongs to the MraZ family
BW732_09375	COG0275	rRNA processing
BW732_09385	COG0768	penicillin binding
BW732_09390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BW732_09395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BW732_09400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BW732_09405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BW732_09410	COG0849	cell division
BW732_09415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BW732_09420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BW732_09425	COG1799	cell septum assembly
BW732_09435	COG2302	S4 RNA-binding domain
BW732_09440	COG3599	regulation of cell shape
BW732_09445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BW732_09450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BW732_09470	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BW732_09475	COG1074	ATP-dependent DNA helicase activity
BW732_09490	COG3853	Toxic anion resistance protein (TelA)
BW732_09510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BW732_09515	COG1335	isochorismatase
BW732_09520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BW732_09525	COG1136	(ABC) transporter
BW732_09530	COG0577	efflux transmembrane transporter activity
BW732_09535	COG2855	membrane
BW732_09540	COG0583	DNA-binding transcription factor activity
BW732_09545	COG4475	Protein of unknown function (DUF436)
BW732_09555	COG2706	6-phosphogluconolactonase activity
BW732_09565	COG0628	permease
BW732_09570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BW732_09575	COG1435	thymidine kinase activity
BW732_09580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BW732_09585	COG2890	protein-(glutamine-N5) methyltransferase activity
BW732_09590	COG0009	L-threonylcarbamoyladenylate synthase
BW732_09595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BW732_09600	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BW732_09610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BW732_09620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BW732_09625	COG3331	DNA recombination
BW732_09640	COG0116	Belongs to the methyltransferase superfamily
BW732_09645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BW732_09665	COG1940	carbohydrate kinase activity
BW732_09670	COG3588	fructose-bisphosphate aldolase
BW732_09675	COG2249	NAD(P)H dehydrogenase (quinone) activity
BW732_09685	COG1131	(ABC) transporter
BW732_09695	COG0737	Belongs to the 5'-nucleotidase family
BW732_09700	COG4470	Protein conserved in bacteria
BW732_09705	COG0647	UMP catabolic process
BW732_09840	COG1393	Belongs to the ArsC family
BW732_09845	COG0509	glycine decarboxylation via glycine cleavage system
BW732_09855	COG0716	FMN binding
BW732_09865	COG3706	GGDEF domain
BW732_09875	COG2738	Putative neutral zinc metallopeptidase
BW732_09885	COG0590	tRNA wobble adenosine to inosine editing
BW732_09895	COG1126	abc transporter atp-binding protein
BW732_09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BW732_09905	COG0765	amino acid transport
BW732_09910	COG0765	amino acid transport
BW732_09920	COG1268	BioY protein
BW732_09935	COG0584	glycerophosphoryl diester phosphodiesterase
BW732_09945	COG1011	Hydrolase
BW732_09955	COG4175	Glycine betaine
BW732_09955	COG3448	diguanylate cyclase activity
BW732_09965	COG0110	maltose O-acetyltransferase activity
BW732_09975	COG2217	Heavy metal translocating P-type atpase
BW732_09980	COG0247	lactate metabolic process
BW732_09985	COG1139	Iron-sulfur cluster binding protein
BW732_09990	COG1556	Lactate utilization protein
BW732_09995	COG1388	LysM domain
BW732_10005	COG2217	Heavy metal translocating P-type atpase
BW732_10030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BW732_10035	COG3763	UPF0154 protein
BW732_10040	COG1132	(ABC) transporter
BW732_10045	COG1132	(ABC) transporter
BW732_10050	COG0659	secondary active sulfate transmembrane transporter activity
BW732_10070	COG1126	abc transporter atp-binding protein
BW732_10075	COG0765	amino acid transport
BW732_10085	COG2267	carboxylic ester hydrolase activity
BW732_10090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BW732_10115	COG2851	Citrate transporter
BW732_10125	COG0511	ligase activity, forming carbon-carbon bonds
BW732_10140	COG3052	prosthetic group binding
BW732_10165	COG0488	(ABC) transporter
BW732_10190	COG0789	Transcriptional regulator
BW732_10190	COG4978	Transcriptional regulator
BW732_10195	COG3804	dihydrodipicolinate reductase
BW732_10200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BW732_10205	COG2011	ABC-type metal ion transport system permease component
BW732_10210	COG1464	Belongs to the NlpA lipoprotein family
BW732_10225	COG1012	belongs to the aldehyde dehydrogenase family
BW732_10225	COG1454	alcohol dehydrogenase
BW732_10235	COG1253	flavin adenine dinucleotide binding
BW732_10240	COG1214	PFAM Peptidase M22, glycoprotease
BW732_10245	COG0456	acetyltransferase
BW732_10255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BW732_10280	COG0668	transmembrane transport
BW732_10295	COG1609	Transcriptional regulator
BW732_10310	COG0154	amidase activity
BW732_10325	COG1609	Transcriptional regulator
BW732_10335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BW732_10340	COG1815	bacterial-type flagellum-dependent cell motility
BW732_10345	COG1558	bacterial-type flagellum-dependent cell motility
BW732_10350	COG1677	Flagellar hook-basal body complex protein FliE
BW732_10360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BW732_10390	COG4786	Flagellar basal body rod
BW732_10410	COG1338	Plays a role in the flagellum-specific transport system
BW732_10415	COG1987	bacterial-type flagellum assembly
BW732_10420	COG1684	flagellar biosynthetic protein fliR
BW732_10425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BW732_10430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BW732_10435	COG1191	sigma factor activity
BW732_10440	COG4786	Flagellar basal body rod
BW732_10445	COG4786	Flagellar basal body rod
BW732_10455	COG0840	transmembrane signaling receptor activity
BW732_10465	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BW732_10470	COG2201	protein-glutamate methylesterase activity
BW732_10475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BW732_10480	COG2198	Histidine kinase
BW732_10480	COG0643	Histidine kinase
BW732_10485	COG1776	CheC inhibitor of MCP methylation
BW732_10490	COG2201	protein-glutamate methylesterase activity
BW732_10500	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BW732_10505	COG1776	CheC inhibitor of MCP methylation
BW732_10505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BW732_10520	COG4786	Flagellar basal body rod
BW732_10520	COG1256	bacterial-type flagellum assembly
BW732_10570	COG0789	Transcriptional regulator
BW732_10575	COG0366	Alpha amylase catalytic
BW732_10580	COG0366	Alpha amylase catalytic
BW732_10585	COG2182	Extracellular solute-binding protein
BW732_10590	COG1175	transmembrane transport
BW732_10595	COG3833	ABC-type maltose transport systems, permease component
BW732_10605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BW732_10610	COG3443	Belongs to the bacterial solute-binding protein 9 family
BW732_10610	COG0803	Belongs to the bacterial solute-binding protein 9 family
BW732_10615	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BW732_10620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BW732_10635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BW732_10640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BW732_10645	COG2011	ABC-type metal ion transport system permease component
BW732_10650	COG1464	Belongs to the NlpA lipoprotein family
BW732_10670	COG3279	Response regulator of the LytR AlgR family
BW732_10675	COG3275	phosphorelay sensor kinase activity
BW732_10685	COG0719	Fe-S assembly protein
BW732_10690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BW732_10695	COG0822	iron-sulfur transferase activity
BW732_10700	COG0719	Fe-S assembly protein
BW732_10740	COG4974	Belongs to the 'phage' integrase family
BW732_10795	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BW732_10800	COG3421	Type III restriction
BW732_10810	COG2801	Transposase and inactivated derivatives
BW732_10830	COG0386	Belongs to the glutathione peroxidase family
BW732_10835	COG4807	Protein conserved in bacteria
BW732_10840	COG1671	Belongs to the UPF0178 family
BW732_10850	COG2249	NAD(P)H dehydrogenase (quinone) activity
BW732_10860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BW732_10865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BW732_10870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BW732_10875	COG2205	protein histidine kinase activity
BW732_10900	COG1174	glycine betaine transport
BW732_10905	COG1132	(ABC) transporter
BW732_10910	COG0514	ATP-dependent DNA helicase (RecQ)
BW732_10920	COG1960	acyl-CoA dehydrogenase activity
BW732_10925	COG0583	DNA-binding transcription factor activity
BW732_10935	COG1960	acyl-CoA dehydrogenase activity
BW732_10940	COG1250	3-hydroxyacyl-CoA dehydrogenase
BW732_10945	COG1024	Enoyl-CoA hydratase
BW732_10950	COG0427	acetyl-CoA hydrolase
BW732_10955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BW732_10960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BW732_10970	COG0280	phosphate acetyltransferase
BW732_10975	COG3426	butyrate kinase activity
BW732_10980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BW732_10985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BW732_10990	COG0022	dehydrogenase e1 component
BW732_10995	COG0508	dehydrogenase complex catalyzes the overall conversion of
BW732_11010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BW732_11015	COG0217	transcriptional regulatory protein
BW732_11020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BW732_11030	COG0531	amino acid
BW732_11035	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BW732_11040	COG0124	histidyl-tRNA synthetase
BW732_11045	COG0482	sulfurtransferase activity
BW732_11050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BW732_11065	COG1012	belongs to the aldehyde dehydrogenase family
BW732_11080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BW732_11085	COG2207	Transcriptional regulator
BW732_11090	COG1012	belongs to the aldehyde dehydrogenase family
BW732_11090	COG1454	alcohol dehydrogenase
BW732_11095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BW732_11100	COG1104	cysteine desulfurase activity
BW732_11115	COG0772	Belongs to the SEDS family
BW732_11120	COG0318	PFAM AMP-dependent synthetase and ligase
BW732_11125	COG0084	hydrolase, TatD family'
BW732_11130	COG1116	anion transmembrane transporter activity
BW732_11140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BW732_11150	COG1160	GTP binding
BW732_11160	COG2261	transglycosylase associated protein
BW732_11170	COG0457	Tetratricopeptide repeat
BW732_11175	COG5582	Belongs to the UPF0302 family
BW732_11180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BW732_11185	COG1694	Mazg nucleotide pyrophosphohydrolase
BW732_11190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BW732_11195	COG0617	tRNA 3'-terminal CCA addition
BW732_11215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BW732_11225	COG1272	protein, Hemolysin III
BW732_11230	COG1307	EDD domain protein, DegV family
BW732_11235	COG2755	lipolytic protein G-D-S-L family
BW732_11240	COG4698	Protein conserved in bacteria
BW732_11245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BW732_11250	COG4479	Belongs to the UPF0346 family
BW732_11255	COG0793	Belongs to the peptidase S41A family
BW732_11255	COG3409	Peptidoglycan-binding domain 1 protein
BW732_11265	COG1254	Belongs to the acylphosphatase family
BW732_11270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BW732_11280	COG1733	regulation of RNA biosynthetic process
BW732_11285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BW732_11290	COG0072	phenylalanine-tRNA ligase activity
BW732_11290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BW732_11295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BW732_11305	COG0778	Nitroreductase
BW732_11310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BW732_11315	COG1846	Transcriptional regulator
BW732_11320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BW732_11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BW732_11335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BW732_11340	COG1028	Short-chain dehydrogenase reductase Sdr
BW732_11345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BW732_11355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity