locus-tag	class	description
MN187_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MN187_00010	COG0592	DNA-directed DNA polymerase activity
MN187_00015	COG0386	Belongs to the glutathione peroxidase family
MN187_00020	COG2501	S4 domain
MN187_00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MN187_00030	COG0187	DNA topoisomerase II activity
MN187_00040	COG0360	Binds together with S18 to 16S ribosomal RNA
MN187_00045	COG0629	single-stranded DNA binding
MN187_00055	COG0359	binds to the 23S rRNA
MN187_00060	COG0305	Participates in initiation and elongation during chromosome replication
MN187_00065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MN187_00085	COG0488	(ABC) transporter
MN187_00090	COG0142	geranyltranstransferase activity
MN187_00130	COG1609	Transcriptional regulator
MN187_00135	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MN187_00145	COG1744	ABC transporter substrate-binding protein PnrA-like
MN187_00150	COG3845	ABC transporter
MN187_00155	COG4603	Belongs to the binding-protein-dependent transport system permease family
MN187_00160	COG1079	Belongs to the binding-protein-dependent transport system permease family
MN187_00165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MN187_00170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MN187_00175	COG0813	purine-nucleoside phosphorylase activity
MN187_00185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MN187_00190	COG0477	Major facilitator Superfamily
MN187_00210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MN187_00215	COG4565	transcriptional regulatory protein
MN187_00220	COG3290	protein histidine kinase activity
MN187_00225	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MN187_00230	COG1242	4 iron, 4 sulfur cluster binding
MN187_00235	COG0671	phosphoesterase, PA-phosphatase related
MN187_00250	COG1388	LysM domain
MN187_00250	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_00255	COG0495	leucyl-tRNA aminoacylation
MN187_00260	COG2244	polysaccharide biosynthetic process
MN187_00265	COG1187	pseudouridine synthase activity
MN187_00270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MN187_00275	COG0577	efflux transmembrane transporter activity
MN187_00275	COG1136	(ABC) transporter
MN187_00325	COG1126	abc transporter atp-binding protein
MN187_00330	COG0765	amino acid transport
MN187_00340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MN187_00345	COG1605	Chorismate mutase
MN187_00345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MN187_00375	COG2814	Major facilitator Superfamily
MN187_00380	COG0673	inositol 2-dehydrogenase activity
MN187_00385	COG1082	Xylose isomerase domain protein TIM barrel
MN187_00390	COG0673	inositol 2-dehydrogenase activity
MN187_00400	COG0039	L-malate dehydrogenase activity
MN187_00405	COG0193	aminoacyl-tRNA hydrolase activity
MN187_00410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MN187_00415	COG2244	polysaccharide biosynthetic process
MN187_00420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MN187_00430	COG1098	S1 RNA binding domain
MN187_00435	COG0037	tRNA processing
MN187_00440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MN187_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MN187_00455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MN187_00460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MN187_00595	COG0542	response to heat
MN187_00605	COG0826	peptidase U32
MN187_00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MN187_00615	COG1271	oxidase subunit
MN187_00620	COG1294	oxidase, subunit
MN187_00625	COG4988	ABC transporter
MN187_00630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MN187_00640	COG0475	glutathione-regulated potassium exporter activity
MN187_00650	COG3942	CHAP domain
MN187_00670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MN187_00680	COG0564	pseudouridine synthase activity
MN187_00685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MN187_00690	COG3679	Belongs to the UPF0342 family
MN187_00695	COG0420	3'-5' exonuclease activity
MN187_00705	COG3481	metal-dependent phosphohydrolase, HD sub domain
MN187_00710	COG3764	Sortase (surface protein transpeptidase)
MN187_00720	COG1181	Belongs to the D-alanine--D-alanine ligase family
MN187_00725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MN187_00735	COG0736	holo-[acyl-carrier-protein] synthase activity
MN187_00755	COG1561	YicC-like family, N-terminal region
MN187_00760	COG0194	GDP metabolic process
MN187_00765	COG1758	RNA polymerase activity
MN187_00770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MN187_00775	COG0242	peptide deformylase activity
MN187_00780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MN187_00785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MN187_00785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MN187_00790	COG0631	protein serine/threonine phosphatase activity
MN187_00795	COG0515	serine threonine protein kinase
MN187_00795	COG2815	serine threonine protein kinase
MN187_00800	COG1162	GTPase activity
MN187_00805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MN187_00825	COG1461	Dihydroxyacetone kinase
MN187_00830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MN187_00835	COG0416	fatty acid biosynthetic process
MN187_00840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MN187_00845	COG2827	Endonuclease containing a URI domain
MN187_00850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MN187_00855	COG0204	Acyl-transferase
MN187_00860	COG0420	3'-5' exonuclease activity
MN187_00875	COG1132	(ABC) transporter
MN187_00880	COG0753	catalase activity
MN187_00890	COG1902	pentaerythritol trinitrate reductase activity
MN187_00935	COG3859	Proton-coupled thiamine transporter YuaJ
MN187_00940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MN187_00945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MN187_00950	COG1780	Probably involved in ribonucleotide reductase function
MN187_00955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MN187_00975	COG0745	RESPONSE REGULATOR receiver
MN187_00980	COG5002	protein histidine kinase activity
MN187_00995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MN187_01000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MN187_01005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MN187_01015	COG2003	Belongs to the UPF0758 family
MN187_01030	COG0488	(ABC) transporter
MN187_01065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MN187_01075	COG0740	serine-type endopeptidase activity
MN187_01080	COG0180	Tryptophanyl-tRNA synthetase
MN187_01085	COG1393	Belongs to the ArsC family
MN187_01090	COG4862	establishment of competence for transformation
MN187_01100	COG1045	serine acetyltransferase
MN187_01120	COG1733	regulation of RNA biosynthetic process
MN187_01135	COG0640	Transcriptional regulator
MN187_01140	COG2217	Heavy metal translocating P-type atpase
MN187_01180	COG0745	RESPONSE REGULATOR receiver
MN187_01195	COG0625	glutathione transferase activity
MN187_01205	COG3527	Alpha-acetolactate decarboxylase
MN187_01210	COG0783	Belongs to the Dps family
MN187_01215	COG0038	chloride channel
MN187_01240	COG0318	PFAM AMP-dependent synthetase and ligase
MN187_01245	COG1169	isochorismate synthase
MN187_01250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MN187_01255	COG0596	Alpha beta hydrolase
MN187_01260	COG4948	Mandelate Racemase Muconate Lactonizing
MN187_01270	COG2252	PERMEase
MN187_01285	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MN187_01290	COG0431	NADPH-dependent FMN reductase
MN187_01295	COG1854	S-ribosylhomocysteine lyase activity
MN187_01300	COG0803	Belongs to the bacterial solute-binding protein 9 family
MN187_01300	COG3443	Belongs to the bacterial solute-binding protein 9 family
MN187_01305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MN187_01315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MN187_01325	COG0523	cobalamin synthesis protein
MN187_01340	COG0142	geranyltranstransferase activity
MN187_01345	COG1346	cytolysis
MN187_01355	COG3279	Response regulator of the LytR AlgR family
MN187_01360	COG3275	phosphorelay sensor kinase activity
MN187_01380	COG0628	permease
MN187_01390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MN187_01395	COG1426	Protein conserved in bacteria
MN187_01400	COG1028	Short-chain dehydrogenase reductase Sdr
MN187_01405	COG0612	Peptidase, M16
MN187_01410	COG0612	Peptidase, M16
MN187_01415	COG1970	mechanosensitive ion channel activity
MN187_01420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MN187_01425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MN187_01430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MN187_01435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MN187_01440	COG1121	(ABC) transporter
MN187_01445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MN187_01450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MN187_01455	COG1177	transmembrane transport
MN187_01460	COG1176	ABC-type spermidine putrescine transport system, permease component I
MN187_01465	COG3842	ATPase activity
MN187_01475	COG0604	alcohol dehydrogenase
MN187_01480	COG1473	amidohydrolase
MN187_01485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MN187_01490	COG0038	chloride channel
MN187_01495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MN187_01500	COG0708	Exodeoxyribonuclease III
MN187_01510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MN187_01515	COG0802	atpase or kinase
MN187_01520	COG0789	Transcriptional regulator
MN187_01540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MN187_01550	COG1012	belongs to the aldehyde dehydrogenase family
MN187_01555	COG1882	Formate acetyltransferase
MN187_01560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MN187_01565	COG4810	utilization protein
MN187_01585	COG4820	ethanolamine utilization protein (EutJ)
MN187_01605	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
MN187_01610	COG1012	belongs to the aldehyde dehydrogenase family
MN187_01610	COG1454	alcohol dehydrogenase
MN187_01615	COG4869	propanediol catabolic process
MN187_01625	COG0446	pyridine nucleotide-disulphide oxidoreductase
MN187_01630	COG0280	phosphate acetyltransferase
MN187_01635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MN187_01640	COG0561	phosphatase activity
MN187_01650	COG2502	aspartate--ammonia ligase
MN187_01655	COG1609	Transcriptional regulator
MN187_01665	COG1175	transmembrane transport
MN187_01670	COG0395	ABC-type sugar transport system, permease component
MN187_01675	COG1621	beta-fructofuranosidase activity
MN187_01700	COG1940	carbohydrate kinase activity
MN187_01715	COG2814	Major facilitator Superfamily
MN187_01720	COG1476	TRANSCRIPTIONal
MN187_01725	COG2807	transmembrane transport
MN187_01730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MN187_01735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MN187_01745	COG1464	Belongs to the NlpA lipoprotein family
MN187_01750	COG1473	amidohydrolase
MN187_01755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MN187_01760	COG1959	2 iron, 2 sulfur cluster binding
MN187_01780	COG1363	Peptidase, m42
MN187_01785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MN187_01790	COG0589	response to stress
MN187_01795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN187_01800	COG4472	Bacterial protein of unknown function (DUF965)
MN187_01805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MN187_01810	COG3906	Belongs to the UPF0473 family
MN187_01830	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MN187_01845	COG1193	negative regulation of DNA recombination
MN187_01850	COG3118	belongs to the thioredoxin family
MN187_01855	COG0322	excinuclease ABC activity
MN187_01865	COG1252	NADH dehydrogenase
MN187_01870	COG1760	l-serine dehydratase
MN187_01875	COG1760	l-serine dehydratase
MN187_01880	COG1546	Belongs to the CinA family
MN187_01880	COG1058	Belongs to the CinA family
MN187_01885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MN187_01890	COG1418	mRNA catabolic process
MN187_01895	COG1328	CTP reductase activity
MN187_01910	COG1363	Peptidase, m42
MN187_01915	COG1234	tRNA 3'-trailer cleavage
MN187_01920	COG0095	Lipoate-protein ligase
MN187_01925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MN187_01935	COG0537	adenosine 5'-monophosphoramidase activity
MN187_01940	COG1131	(ABC) transporter
MN187_01945	COG4473	ABC transporter
MN187_01950	COG0510	thiamine kinase activity
MN187_01955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MN187_01965	COG2376	Dihydroxyacetone kinase
MN187_01970	COG1461	Dihydroxyacetone kinase
MN187_01975	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MN187_01985	COG2376	Dihydroxyacetone kinase
MN187_02000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MN187_02005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MN187_02010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MN187_02015	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MN187_02020	COG4122	O-methyltransferase activity
MN187_02035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MN187_02045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MN187_02050	COG0006	proline dipeptidase activity
MN187_02055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MN187_02060	COG1302	Protein conserved in bacteria
MN187_02065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MN187_02075	COG1570	exodeoxyribonuclease VII activity
MN187_02080	COG1722	exodeoxyribonuclease VII activity
MN187_02085	COG0142	geranyltranstransferase activity
MN187_02090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MN187_02095	COG1438	arginine binding
MN187_02100	COG0497	DNA recombination
MN187_02115	COG2001	Belongs to the MraZ family
MN187_02120	COG0275	rRNA processing
MN187_02130	COG0768	penicillin binding
MN187_02135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MN187_02140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MN187_02145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MN187_02155	COG0849	cell division
MN187_02160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MN187_02165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MN187_02170	COG1799	cell septum assembly
MN187_02180	COG2302	S4 RNA-binding domain
MN187_02185	COG3599	regulation of cell shape
MN187_02190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MN187_02205	COG1609	Transcriptional regulator
MN187_02210	COG2723	6-phospho-beta-galactosidase activity
MN187_02215	COG2190	(PTS) system
MN187_02215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_02215	COG1263	PTS System
MN187_02220	COG3711	transcriptional antiterminator
MN187_02235	COG4129	membrane
MN187_02245	COG1876	peptidase activity
MN187_02250	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_02270	COG2183	response to ionizing radiation
MN187_02275	COG3091	SprT-like family
MN187_02290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MN187_02295	COG2011	ABC-type metal ion transport system permease component
MN187_02300	COG1464	Belongs to the NlpA lipoprotein family
MN187_02310	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MN187_02315	COG1104	cysteine desulfurase activity
MN187_02320	COG0301	tRNA thio-modification
MN187_02325	COG2309	aminopeptidase activity
MN187_02335	COG0716	FMN binding
MN187_02340	COG0024	Methionine aminopeptidase
MN187_02350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MN187_02355	COG1316	TRANSCRIPTIONal
MN187_02360	COG1134	teichoic acid transport
MN187_02365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MN187_02375	COG1682	transport, permease protein
MN187_02380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MN187_02385	COG0463	Glycosyl transferase, family 2
MN187_02385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MN187_02395	COG0489	protein tyrosine kinase activity
MN187_02400	COG4464	protein tyrosine phosphatase activity
MN187_02410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MN187_02415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MN187_02425	COG0438	transferase activity, transferring glycosyl groups
MN187_02430	COG1216	Glycosyl transferase, family 2
MN187_02480	COG2137	regulation of response to DNA damage stimulus
MN187_02485	COG1194	a g-specific adenine glycosylase
MN187_02490	COG3557	Belongs to the UPF0374 family
MN187_02500	COG2153	protein acetylation
MN187_02505	COG0628	permease
MN187_02510	COG1253	flavin adenine dinucleotide binding
MN187_02515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MN187_02535	COG5434	Belongs to the glycosyl hydrolase 28 family
MN187_02570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MN187_02575	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_02575	COG3942	CHAP domain
MN187_02605	COG3404	Formiminotransferase-cyclodeaminase
MN187_02620	COG0531	amino acid
MN187_02625	COG2986	histidine ammonia-lyase
MN187_02630	COG0124	histidyl-tRNA synthetase
MN187_02635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MN187_02640	COG1228	amidohydrolase
MN187_02645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MN187_02655	COG1070	Carbohydrate kinase
MN187_02660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MN187_02665	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MN187_02670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MN187_02675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MN187_02680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MN187_02690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MN187_02700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MN187_02705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MN187_02710	COG0138	bifunctional purine biosynthesis protein purh
MN187_02725	COG1737	Transcriptional regulator
MN187_02730	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MN187_02735	COG2190	(PTS) system
MN187_02735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_02735	COG1263	PTS System
MN187_02740	COG2190	(PTS) system
MN187_02740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_02740	COG1263	PTS System
MN187_02750	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MN187_02755	COG1534	Rna-binding protein
MN187_02760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MN187_02765	COG1713	HD superfamily hydrolase involved in NAD metabolism
MN187_02770	COG0799	negative regulation of ribosome biogenesis
MN187_02775	COG2226	methyltransferase
MN187_02780	COG1323	Belongs to the UPF0348 family
MN187_02790	COG1304	FMN binding
MN187_02815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MN187_02820	COG1234	tRNA 3'-trailer cleavage
MN187_02825	COG0300	oxidoreductase activity
MN187_02830	COG5416	Lipopolysaccharide assembly protein A domain
MN187_02835	COG0772	Belongs to the SEDS family
MN187_02845	COG1393	Belongs to the ArsC family
MN187_02850	COG0509	glycine decarboxylation via glycine cleavage system
MN187_02860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MN187_02865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MN187_02880	COG1126	abc transporter atp-binding protein
MN187_02885	COG0765	amino acid transport
MN187_02910	COG2195	Cleaves the N-terminal amino acid of tripeptides
MN187_02920	COG1396	sequence-specific DNA binding
MN187_02930	COG2706	6-phosphogluconolactonase activity
MN187_02935	COG0564	pseudouridine synthase activity
MN187_02950	COG1378	Sugar-specific transcriptional regulator TrmB
MN187_02970	COG0513	Belongs to the DEAD box helicase family
MN187_02980	COG1435	thymidine kinase activity
MN187_02985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MN187_02990	COG2890	protein-(glutamine-N5) methyltransferase activity
MN187_02995	COG0009	L-threonylcarbamoyladenylate synthase
MN187_03000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MN187_03005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MN187_03010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MN187_03025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MN187_03030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MN187_03035	COG3331	DNA recombination
MN187_03040	COG3599	regulation of cell shape
MN187_03050	COG0116	Belongs to the methyltransferase superfamily
MN187_03055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MN187_03060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MN187_03065	COG3588	fructose-bisphosphate aldolase
MN187_03070	COG2249	NAD(P)H dehydrogenase (quinone) activity
MN187_03085	COG2365	Tyrosine phosphatase family
MN187_03090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MN187_03095	COG0737	Belongs to the 5'-nucleotidase family
MN187_03100	COG4470	Protein conserved in bacteria
MN187_03105	COG0647	UMP catabolic process
MN187_03115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MN187_03120	COG0492	ferredoxin-NADP+ reductase activity
MN187_03135	COG1132	(ABC) transporter
MN187_03150	COG1482	cell wall glycoprotein biosynthetic process
MN187_03155	COG0686	Belongs to the AlaDH PNT family
MN187_03160	COG3442	glutamine amidotransferase
MN187_03165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MN187_03170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MN187_03175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MN187_03190	COG1278	Cold shock
MN187_03195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MN187_03200	COG0735	belongs to the Fur family
MN187_03205	COG3853	Toxic anion resistance protein (TelA)
MN187_03230	COG1335	isochorismatase
MN187_03235	COG2855	membrane
MN187_03240	COG0583	DNA-binding transcription factor activity
MN187_03250	COG0531	amino acid
MN187_03255	COG1511	domain protein
MN187_03260	COG0076	glutamate decarboxylase activity
MN187_03285	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MN187_03285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MN187_03290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MN187_03290	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_03300	COG3715	PTS system
MN187_03305	COG3716	PTS system mannose fructose sorbose family IID component
MN187_03335	COG0390	transport system, permease component
MN187_03340	COG4619	ABC transporter
MN187_03345	COG0572	uridine kinase
MN187_03350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MN187_03355	COG1098	S1 RNA binding domain
MN187_03405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MN187_03405	COG1199	ATP-dependent helicase activity
MN187_03415	COG0436	Aminotransferase
MN187_03430	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MN187_03445	COG1316	TRANSCRIPTIONal
MN187_03450	COG3579	cysteine-type endopeptidase activity
MN187_03455	COG0556	nucleotide-excision repair
MN187_03460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MN187_03470	COG0573	inorganic phosphate transmembrane transporter activity
MN187_03475	COG0581	inorganic phosphate transmembrane transporter activity
MN187_03480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MN187_03485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MN187_03490	COG0704	Plays a role in the regulation of phosphate uptake
MN187_03515	COG1983	PspC domain protein
MN187_03520	COG1950	PFAM Membrane protein of
MN187_03525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MN187_03530	COG0228	four-way junction DNA binding
MN187_03535	COG1837	Belongs to the UPF0109 family
MN187_03540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MN187_03545	COG0574	Belongs to the PEP-utilizing enzyme family
MN187_03545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MN187_03550	COG0517	IMP dehydrogenase activity
MN187_03555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MN187_03575	COG0446	pyridine nucleotide-disulphide oxidoreductase
MN187_03580	COG1937	Protein conserved in bacteria
MN187_03590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MN187_03595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MN187_03600	COG0302	gtp cyclohydrolase
MN187_03640	COG1609	Transcriptional regulator
MN187_03650	COG1869	D-ribose catabolic process
MN187_03655	COG4975	Glucose uptake
MN187_03670	COG1979	alcohol dehydrogenase
MN187_03675	COG1620	l-lactate permease
MN187_03680	COG0247	lactate metabolic process
MN187_03685	COG1139	Iron-sulfur cluster binding protein
MN187_03690	COG1556	Lactate utilization protein
MN187_03720	COG0765	amino acid transport
MN187_03725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MN187_03730	COG1942	4-Oxalocrotonate Tautomerase
MN187_03745	COG0557	exoribonuclease II activity
MN187_03750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MN187_03755	COG0356	it plays a direct role in the translocation of protons across the membrane
MN187_03760	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MN187_03765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MN187_03770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MN187_03775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MN187_03780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MN187_03785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MN187_03790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MN187_03800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MN187_03810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MN187_03820	COG0559	Belongs to the binding-protein-dependent transport system permease family
MN187_03830	COG0411	ABC transporter
MN187_03840	COG0517	IMP dehydrogenase activity
MN187_03865	COG2188	Transcriptional regulator
MN187_03870	COG1739	Uncharacterized protein family UPF0029
MN187_03885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MN187_03900	COG0488	(ABC) transporter
MN187_03905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MN187_03915	COG0768	penicillin binding
MN187_03920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MN187_03930	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MN187_03935	COG0477	Major facilitator Superfamily
MN187_03945	COG2814	Major facilitator Superfamily
MN187_03955	COG0587	DNA-directed DNA polymerase activity
MN187_03960	COG0205	6-phosphofructokinase activity
MN187_03970	COG2814	Major facilitator Superfamily
MN187_03975	COG2996	Protein conserved in bacteria
MN187_03980	COG0735	belongs to the Fur family
MN187_03985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MN187_03995	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MN187_04000	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MN187_04005	COG1187	pseudouridine synthase activity
MN187_04010	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MN187_04015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MN187_04015	COG2755	lipolytic protein G-D-S-L family
MN187_04030	COG0514	ATP-dependent DNA helicase (RecQ)
MN187_04045	COG0539	negative regulation of cytoplasmic translation
MN187_04050	COG1160	GTP binding
MN187_04065	COG0457	Tetratricopeptide repeat
MN187_04070	COG5582	Belongs to the UPF0302 family
MN187_04075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MN187_04080	COG1694	Mazg nucleotide pyrophosphohydrolase
MN187_04085	COG0617	tRNA 3'-terminal CCA addition
MN187_04105	COG2153	protein acetylation
MN187_04110	COG1073	alpha beta
MN187_04115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MN187_04125	COG1846	Transcriptional regulator
MN187_04135	COG0778	Nitroreductase
MN187_04145	COG3759	membrane
MN187_04160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MN187_04165	COG0460	homoserine dehydrogenase
MN187_04165	COG0527	aspartate kinase activity
MN187_04170	COG0460	homoserine dehydrogenase
MN187_04190	COG0076	glutamate decarboxylase activity
MN187_04195	COG0726	polysaccharide deacetylase
MN187_04210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MN187_04225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MN187_04230	COG0457	Tetratricopeptide repeat
MN187_04230	COG0705	Rhomboid family
MN187_04240	COG1940	carbohydrate kinase activity
MN187_04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MN187_04250	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MN187_04255	COG1573	uracil-dna glycosylase
MN187_04265	COG0584	glycerophosphoryl diester phosphodiesterase
MN187_04270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MN187_04275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MN187_04280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MN187_04285	COG0789	Transcriptional regulator
MN187_04295	COG0393	Putative heavy-metal-binding
MN187_04305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MN187_04320	COG1307	EDD domain protein, DegV family
MN187_04325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MN187_04335	COG0513	Belongs to the DEAD box helicase family
MN187_04340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MN187_04345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MN187_04350	COG2011	ABC-type metal ion transport system permease component
MN187_04355	COG1464	Belongs to the NlpA lipoprotein family
MN187_04370	COG0719	Fe-S assembly protein
MN187_04375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MN187_04385	COG0719	Fe-S assembly protein
MN187_04410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MN187_04465	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MN187_04470	COG1674	ftsk spoiiie
MN187_04470	COG1280	lysine exporter protein (LysE YggA)
MN187_04520	COG0577	efflux transmembrane transporter activity
MN187_04525	COG1136	(ABC) transporter
MN187_04535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MN187_04540	COG0358	DNA primase activity
MN187_04545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MN187_04560	COG1136	(ABC) transporter
MN187_04565	COG0577	efflux transmembrane transporter activity
MN187_04565	COG1136	(ABC) transporter
MN187_04570	COG1131	(ABC) transporter
MN187_04595	COG2514	catechol 2,3-dioxygenase activity
MN187_04600	COG1687	branched-chain amino acid
MN187_04605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MN187_04610	COG0488	(ABC) transporter
MN187_04615	COG1368	sulfuric ester hydrolase activity
MN187_04620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MN187_04625	COG0710	3-dehydroquinate dehydratase activity
MN187_04630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MN187_04640	COG2081	HI0933 family
MN187_04645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MN187_04650	COG0166	Belongs to the GPI family
MN187_04680	COG0187	DNA topoisomerase II activity
MN187_04685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MN187_04695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MN187_04710	COG1227	inorganic diphosphatase activity
MN187_04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MN187_04755	COG0745	RESPONSE REGULATOR receiver
MN187_04760	COG5002	protein histidine kinase activity
MN187_04760	COG3850	Histidine kinase
MN187_04765	COG4476	Belongs to the UPF0223 family
MN187_04770	COG0483	inositol monophosphate 1-phosphatase activity
MN187_04775	COG1217	gtp-binding protein TYPA
MN187_04790	COG2384	SAM-dependent methyltransferase
MN187_04795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MN187_04800	COG2195	Cleaves the N-terminal amino acid of tripeptides
MN187_04805	COG0542	response to heat
MN187_04830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MN187_04845	COG2188	Transcriptional regulator
MN187_04855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MN187_04855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MN187_04860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MN187_04865	COG0237	dephospho-CoA kinase activity
MN187_04875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MN187_04885	COG1484	DNA-dependent DNA replication
MN187_04895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MN187_04900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MN187_04905	COG1832	CoA-binding protein
MN187_04925	COG3639	organic phosphonate transmembrane transporter activity
MN187_04930	COG0737	Belongs to the 5'-nucleotidase family
MN187_04940	COG2337	Toxic component of a toxin-antitoxin (TA) module
MN187_04965	COG1160	GTP binding
MN187_04980	COG0481	GTPase activity
MN187_05005	COG2217	Heavy metal translocating P-type atpase
MN187_05010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MN187_05015	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MN187_05025	COG0582	viral genome integration into host DNA
MN187_05040	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MN187_05050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MN187_05055	COG0287	Prephenate dehydrogenase
MN187_05065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MN187_05070	COG0077	Prephenate dehydratase
MN187_05100	COG2249	NAD(P)H dehydrogenase (quinone) activity
MN187_05105	COG4974	Belongs to the 'phage' integrase family
MN187_05120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MN187_05140	COG4120	Belongs to the binding-protein-dependent transport system permease family
MN187_05160	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MN187_05180	COG3223	Belongs to the PsiE family
MN187_05190	COG0284	orotidine-5'-phosphate decarboxylase activity
MN187_05195	COG0167	dihydroorotate dehydrogenase activity
MN187_05200	COG0543	2 iron, 2 sulfur cluster binding
MN187_05215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MN187_05220	COG0540	Belongs to the ATCase OTCase family
MN187_05225	COG2233	PERMEase
MN187_05235	COG0564	pseudouridine synthase activity
MN187_05245	COG0626	cystathionine gamma-synthase activity
MN187_05250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MN187_05265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MN187_05290	COG0577	efflux transmembrane transporter activity
MN187_05295	COG1136	(ABC) transporter
MN187_05305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MN187_05310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MN187_05320	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MN187_05325	COG2252	PERMEase
MN187_05330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MN187_05340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MN187_05345	COG0154	amidase activity
MN187_05350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MN187_05355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MN187_05360	COG0210	DNA helicase
MN187_05370	COG1132	(ABC) transporter
MN187_05375	COG1132	(ABC) transporter
MN187_05380	COG3763	UPF0154 protein
MN187_05385	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MN187_05390	COG0765	amino acid transport
MN187_05395	COG0765	amino acid transport
MN187_05400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MN187_05410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MN187_05420	COG0751	glycine-tRNA ligase activity
MN187_05425	COG0752	glycyl-tRNA synthetase alpha subunit
MN187_05430	COG1381	Involved in DNA repair and RecF pathway recombination
MN187_05435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MN187_05445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MN187_05450	COG1480	7TM receptor with intracellular HD hydrolase
MN187_05455	COG1702	phosphate starvation-inducible protein PhoH
MN187_05460	COG1610	YqeY-like protein
MN187_05475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MN187_05490	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MN187_05495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MN187_05500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MN187_05505	COG4974	Belongs to the 'phage' integrase family
MN187_05510	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MN187_05515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MN187_05520	COG0758	DNA mediated transformation
MN187_05525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MN187_05540	COG0793	Belongs to the peptidase S41A family
MN187_05540	COG3409	Peptidoglycan-binding domain 1 protein
MN187_05545	COG4479	Belongs to the UPF0346 family
MN187_05555	COG2755	lipolytic protein G-D-S-L family
MN187_05560	COG1307	EDD domain protein, DegV family
MN187_05565	COG1272	protein, Hemolysin III
MN187_05570	COG1609	Transcriptional regulator
MN187_05580	COG0772	Belongs to the SEDS family
MN187_05600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MN187_05610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MN187_05620	COG0488	(ABC) transporter
MN187_05625	COG2860	membrane
MN187_05635	COG2723	6-phospho-beta-galactosidase activity
MN187_05645	COG2188	Transcriptional regulator
MN187_05650	COG1671	Belongs to the UPF0178 family
MN187_05655	COG4807	Protein conserved in bacteria
MN187_05670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MN187_05675	COG1126	abc transporter atp-binding protein
MN187_05690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MN187_05695	COG0482	sulfurtransferase activity
MN187_05705	COG1104	cysteine desulfurase activity
MN187_05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MN187_05715	COG0656	L-ascorbic acid biosynthetic process
MN187_05725	COG0072	phenylalanine-tRNA ligase activity
MN187_05725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN187_05730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MN187_05735	COG1733	regulation of RNA biosynthetic process
MN187_05745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MN187_05750	COG1254	Belongs to the acylphosphatase family
MN187_05755	COG0706	membrane insertase activity
MN187_05780	COG0640	Transcriptional regulator
MN187_05785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MN187_05795	COG1129	ABC transporter
MN187_05820	COG0668	transmembrane transport
MN187_05825	COG1473	amidohydrolase
MN187_05830	COG0517	IMP dehydrogenase activity
MN187_05840	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MN187_05845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MN187_05850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MN187_05855	COG0456	acetyltransferase
MN187_05865	COG1214	PFAM Peptidase M22, glycoprotease
MN187_05875	COG1764	response to oxidative stress
MN187_05890	COG0363	glucosamine-6-phosphate deaminase activity
MN187_05905	COG2151	metal-sulfur cluster biosynthetic enzyme
MN187_05910	COG0825	malonyl-CoA metabolic process
MN187_05915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MN187_05920	COG0439	Biotin carboxylase
MN187_05925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MN187_05935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MN187_05945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MN187_05955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MN187_05960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MN187_05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MN187_05980	COG0737	Belongs to the 5'-nucleotidase family
MN187_05995	COG0772	Belongs to the SEDS family
MN187_06005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MN187_06010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MN187_06015	COG1481	regulation of sporulation
MN187_06025	COG1660	Displays ATPase and GTPase activities
MN187_06030	COG2177	Part of the ABC transporter FtsEX involved in
MN187_06035	COG2884	Cell division ATP-binding protein ftsE
MN187_06045	COG0653	protein targeting
MN187_06070	COG3052	prosthetic group binding
MN187_06080	COG3493	citrate carrier protein
MN187_06085	COG0281	malic enzyme
MN187_06090	COG2390	Transcriptional regulator
MN187_06125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MN187_06130	COG0149	triose-phosphate isomerase activity
MN187_06145	COG2390	Transcriptional regulator
MN187_06150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MN187_06160	COG0740	serine-type endopeptidase activity
MN187_06170	COG5002	protein histidine kinase activity
MN187_06175	COG0745	RESPONSE REGULATOR receiver
MN187_06180	COG1132	(ABC) transporter
MN187_06185	COG1132	(ABC) transporter
MN187_06190	COG0516	GMP reductase activity
MN187_06195	COG4989	oxidoreductase activity
MN187_06210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MN187_06215	COG1388	LysM domain
MN187_06215	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_06230	COG4467	Involved in initiation control of chromosome replication
MN187_06235	COG1774	PSP1 C-terminal conserved region
MN187_06240	COG0470	DNA polymerase III
MN187_06245	COG3870	Protein conserved in bacteria
MN187_06250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MN187_06255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MN187_06260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MN187_06265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MN187_06275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MN187_06285	COG1073	alpha beta
MN187_06300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MN187_06305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MN187_06310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MN187_06330	COG0335	large ribosomal subunit rRNA binding
MN187_06335	COG0336	Belongs to the RNA methyltransferase TrmD family
MN187_06340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MN187_06365	COG1368	sulfuric ester hydrolase activity
MN187_06380	COG0254	rRNA binding
MN187_06385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MN187_06390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MN187_06395	COG0191	fructose-bisphosphate aldolase activity
MN187_06410	COG3343	RNA polymerase activity
MN187_06420	COG0095	Lipoate-protein ligase
MN187_06425	COG1078	dGTPase activity
MN187_06430	COG0561	phosphatase activity
MN187_06435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MN187_06440	COG0697	spore germination
MN187_06445	COG0803	Belongs to the bacterial solute-binding protein 9 family
MN187_06450	COG0484	heat shock protein binding
MN187_06455	COG0443	Heat shock 70 kDa protein
MN187_06460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MN187_06465	COG1420	regulation of RNA biosynthetic process
MN187_06470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MN187_06475	COG0196	riboflavin kinase activity
MN187_06480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MN187_06485	COG0673	inositol 2-dehydrogenase activity
MN187_06490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MN187_06505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MN187_06510	COG0195	Participates in both transcription termination and antitermination
MN187_06515	COG0779	Required for maturation of 30S ribosomal subunits
MN187_06525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MN187_06550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MN187_06560	COG0442	prolyl-tRNA aminoacylation
MN187_06565	COG0750	zinc metalloprotease
MN187_06570	COG4589	Belongs to the CDS family
MN187_06575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MN187_06580	COG0233	cytoplasmic translational termination
MN187_06585	COG0528	UMP kinase activity
MN187_06590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MN187_06595	COG0052	Belongs to the universal ribosomal protein uS2 family
MN187_06620	COG1968	undecaprenyl-diphosphatase activity
MN187_06625	COG2217	Heavy metal translocating P-type atpase
MN187_06635	COG1307	EDD domain protein, DegV family
MN187_06645	COG1466	dna polymerase III delta subunit
MN187_06650	COG2333	competence protein COMEC
MN187_06650	COG0658	competence protein
MN187_06655	COG2131	deaminase
MN187_06660	COG1596	polysaccharide export
MN187_06660	COG1555	photosystem II stabilization
MN187_06665	COG3480	Lon protease (S16) C-terminal proteolytic domain
MN187_06670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MN187_06675	COG0742	ribosomal rna small subunit methyltransferase
MN187_06680	COG4471	UPF0298 protein
MN187_06695	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MN187_06700	COG0772	Belongs to the SEDS family
MN187_06705	COG4838	Belongs to the UPF0358 family
MN187_06710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MN187_06725	COG4841	protein insertion into membrane
MN187_06730	COG0569	domain protein
MN187_06735	COG2197	response regulator
MN187_06750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MN187_06755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MN187_06760	COG2824	Alkylphosphonate utilization operon protein PhnA
MN187_06775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MN187_06780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MN187_06780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MN187_06785	COG0726	polysaccharide deacetylase
MN187_06790	COG1268	BioY protein
MN187_06800	COG0823	Involved in the tonB-independent uptake of proteins
MN187_06800	COG1506	peptidase
MN187_06800	COG4946	Tricorn protease homolog
MN187_06805	COG1794	racemase activity, acting on amino acids and derivatives
MN187_06815	COG0367	asparagine synthase
MN187_06825	COG4753	response regulator
MN187_06825	COG2207	Transcriptional regulator
MN187_06830	COG2972	Histidine kinase
MN187_06840	COG1653	transport
MN187_06845	COG0395	ABC-type sugar transport system, permease component
MN187_06850	COG1175	transmembrane transport
MN187_06860	COG2814	Major facilitator Superfamily
MN187_06875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MN187_06885	COG1363	Peptidase, m42
MN187_06890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MN187_06895	COG3425	synthase
MN187_06905	COG4716	Myosin-crossreactive antigen
MN187_06915	COG3973	AAA domain
MN187_06930	COG3448	diguanylate cyclase activity
MN187_06930	COG4175	Glycine betaine
MN187_06955	COG0450	alkyl hydroperoxide reductase
MN187_06970	COG1940	carbohydrate kinase activity
MN187_06975	COG2723	6-phospho-beta-galactosidase activity
MN187_06980	COG0446	pyridine nucleotide-disulphide oxidoreductase
MN187_06990	COG1652	LysM domain
MN187_06990	COG2823	Periplasmic or secreted lipoprotein
MN187_06995	COG2217	Heavy metal translocating P-type atpase
MN187_07005	COG5002	protein histidine kinase activity
MN187_07010	COG0745	RESPONSE REGULATOR receiver
MN187_07015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MN187_07020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MN187_07025	COG0544	peptidyl-prolyl cis-trans isomerase activity
MN187_07035	COG4703	Protein of unknown function (DUF1797)
MN187_07040	COG2084	Dehydrogenase
MN187_07050	COG0438	transferase activity, transferring glycosyl groups
MN187_07055	COG0438	transferase activity, transferring glycosyl groups
MN187_07060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MN187_07070	COG0542	response to heat
MN187_07085	COG1595	DNA-templated transcription, initiation
MN187_07090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MN187_07100	COG2076	Multidrug Resistance protein
MN187_07105	COG2076	Multidrug Resistance protein
MN187_07125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MN187_07130	COG2268	Band 7 protein
MN187_07145	COG1136	(ABC) transporter
MN187_07175	COG0436	Aminotransferase
MN187_07180	COG1174	glycine betaine transport
MN187_07190	COG1174	glycine betaine transport
MN187_07205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MN187_07215	COG0583	DNA-binding transcription factor activity
MN187_07220	COG0628	permease
MN187_07255	COG1942	4-Oxalocrotonate Tautomerase
MN187_07260	COG0673	inositol 2-dehydrogenase activity
MN187_07265	COG0531	amino acid
MN187_07270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MN187_07275	COG1126	abc transporter atp-binding protein
MN187_07280	COG0765	amino acid transport
MN187_07295	COG1461	Dihydroxyacetone kinase
MN187_07305	COG0577	efflux transmembrane transporter activity
MN187_07310	COG1136	(ABC) transporter
MN187_07315	COG0642	Histidine kinase
MN187_07320	COG0745	RESPONSE REGULATOR receiver
MN187_07340	COG0716	FMN binding
MN187_07345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MN187_07355	COG0584	glycerophosphoryl diester phosphodiesterase
MN187_07360	COG3338	carbonate dehydratase activity
MN187_07370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MN187_07375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MN187_07380	COG1696	Membrane protein involved in D-alanine export
MN187_07410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MN187_07420	COG1074	ATP-dependent DNA helicase activity
MN187_07425	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MN187_07440	COG3291	Pkd domain containing protein
MN187_07440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MN187_07455	COG0383	alpha-mannosidase activity
MN187_07465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MN187_07470	COG1121	(ABC) transporter
MN187_07485	COG0504	CTP synthase activity
MN187_07490	COG0659	secondary active sulfate transmembrane transporter activity
MN187_07515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MN187_07520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MN187_07525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MN187_07530	COG0427	acetyl-CoA hydrolase
MN187_07535	COG1024	Enoyl-CoA hydratase
MN187_07540	COG1250	3-hydroxyacyl-CoA dehydrogenase
MN187_07545	COG1960	acyl-CoA dehydrogenase activity
MN187_07550	COG0183	Belongs to the thiolase family
MN187_07555	COG0583	DNA-binding transcription factor activity
MN187_07560	COG1960	acyl-CoA dehydrogenase activity
MN187_07565	COG0662	Cupin 2, conserved barrel domain protein
MN187_07575	COG0590	tRNA wobble adenosine to inosine editing
MN187_07585	COG2738	Putative neutral zinc metallopeptidase
MN187_07595	COG2199	diguanylate cyclase activity
MN187_07595	COG2203	Gaf domain
MN187_07600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MN187_07615	COG0366	Alpha amylase catalytic
MN187_07620	COG1263	PTS System
MN187_07620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_07625	COG2188	Transcriptional regulator
MN187_07630	COG1185	polyribonucleotide nucleotidyltransferase activity
MN187_07635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MN187_07640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MN187_07645	COG0242	peptide deformylase activity
MN187_07655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MN187_07665	COG2239	Acts as a magnesium transporter
MN187_07670	COG0564	pseudouridine synthase activity
MN187_07680	COG2357	RelA SpoT domain protein
MN187_07685	COG4116	CYTH
MN187_07695	COG1164	Oligoendopeptidase f
MN187_07700	COG4469	Competence protein
MN187_07705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MN187_07715	COG0737	Belongs to the 5'-nucleotidase family
MN187_07720	COG0488	(ABC) transporter
MN187_07725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MN187_07735	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MN187_07740	COG0459	protein refolding
MN187_07765	COG0217	transcriptional regulatory protein
MN187_07775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MN187_07780	COG4109	DRTGG domain
MN187_07790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MN187_07805	COG1757	Na H antiporter
MN187_07815	COG0250	Participates in transcription elongation, termination and antitermination
MN187_07825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MN187_07845	COG1597	lipid kinase activity
MN187_07850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MN187_07855	COG0406	alpha-ribazole phosphatase activity
MN187_07860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MN187_07865	COG0500	methyltransferase
MN187_07870	COG3142	Participates in the control of copper homeostasis
MN187_07885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MN187_07890	COG1263	PTS System
MN187_07890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_07895	COG1668	transmembrane transport
MN187_07900	COG4152	abc transporter atp-binding protein
MN187_07935	COG1012	belongs to the aldehyde dehydrogenase family
MN187_07935	COG1454	alcohol dehydrogenase
MN187_07950	COG5002	protein histidine kinase activity
MN187_07955	COG2190	(PTS) system
MN187_07955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_07955	COG1263	PTS System
MN187_07965	COG1737	Transcriptional regulator
MN187_07970	COG1486	melibiose metabolic process
MN187_07975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_07975	COG1263	PTS System
MN187_07980	COG0673	inositol 2-dehydrogenase activity
MN187_07985	COG1082	Xylose isomerase domain protein TIM barrel
MN187_08000	COG1917	Cupin 2, conserved barrel domain protein
MN187_08000	COG2207	Transcriptional regulator
MN187_08015	COG1263	PTS System
MN187_08015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_08015	COG2190	(PTS) system
MN187_08025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MN187_08040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MN187_08045	COG0222	ribosome binding
MN187_08050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MN187_08055	COG0081	regulation of translation
MN187_08070	COG2217	Heavy metal translocating P-type atpase
MN187_08085	COG0343	queuine tRNA-ribosyltransferase activity
MN187_08090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MN187_08095	COG2255	four-way junction helicase activity
MN187_08100	COG0632	four-way junction helicase activity
MN187_08110	COG0424	maF-like protein
MN187_08115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MN187_08120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MN187_08130	COG1692	metallophosphoesterase
MN187_08145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MN187_08150	COG4684	Psort location CytoplasmicMembrane, score
MN187_08165	COG1054	Belongs to the UPF0176 family
MN187_08170	COG2814	Major facilitator Superfamily
MN187_08175	COG1490	D-aminoacyl-tRNA deacylase activity
MN187_08180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MN187_08185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MN187_08190	COG2264	protein methyltransferase activity
MN187_08200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MN187_08210	COG0589	response to stress
MN187_08215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MN187_08220	COG0827	DNA restriction-modification system
MN187_08250	COG1459	type II secretion system
MN187_08255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MN187_08260	COG0217	transcriptional regulatory protein
MN187_08275	COG4708	membrane
MN187_08280	COG1028	Short-chain dehydrogenase reductase Sdr
MN187_08295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MN187_08305	COG2813	Specifically methylates the guanine in position
MN187_08310	COG2755	lipolytic protein G-D-S-L family
MN187_08320	COG1072	(Pantothenic acid kinase))
MN187_08325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MN187_08325	COG0519	Catalyzes the synthesis of GMP from XMP
MN187_08345	COG1454	alcohol dehydrogenase
MN187_08345	COG1012	belongs to the aldehyde dehydrogenase family
MN187_08350	COG3292	Two component regulator propeller
MN187_08350	COG2205	protein histidine kinase activity
MN187_08350	COG0745	RESPONSE REGULATOR receiver
MN187_08355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MN187_08370	COG3732	PTS system glucitol sorbitol-specific
MN187_08375	COG3730	PTS system glucitol sorbitol-specific
MN187_08385	COG3711	transcriptional antiterminator
MN187_08385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MN187_08420	COG2723	6-phospho-beta-galactosidase activity
MN187_08425	COG1263	PTS System
MN187_08425	COG2190	(PTS) system
MN187_08425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_08430	COG3711	transcriptional antiterminator
MN187_08450	COG0673	inositol 2-dehydrogenase activity
MN187_08455	COG1132	(ABC) transporter
MN187_08465	COG5503	Protein of unknown function (DUF1447)
MN187_08475	COG2153	protein acetylation
MN187_08480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MN187_08485	COG1278	Cold shock
MN187_08490	COG2003	Belongs to the UPF0758 family
MN187_08495	COG0546	phosphoglycolate phosphatase activity
MN187_08500	COG0285	dihydrofolate synthase activity
MN187_08505	COG0525	valine-tRNA ligase activity
MN187_08510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MN187_08515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MN187_08530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MN187_08535	COG4466	Protein conserved in bacteria
MN187_08550	COG2814	Major facilitator Superfamily
MN187_08565	COG3688	RNA-binding protein containing a PIN domain
MN187_08570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MN187_08575	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MN187_08580	COG0215	cysteine-tRNA ligase activity
MN187_08585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MN187_08590	COG4956	integral membrane protein (PIN domain superfamily)
MN187_08600	COG0756	dUTP diphosphatase activity
MN187_08605	COG3158	transport of potassium into the cell
MN187_08610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MN187_08615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MN187_08635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MN187_08650	COG0110	maltose O-acetyltransferase activity
MN187_08655	COG0436	Aminotransferase
MN187_08675	COG0351	phosphomethylpyrimidine kinase
MN187_08680	COG0352	thiamine-phosphate diphosphorylase activity
MN187_08685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MN187_08695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MN187_08705	COG1129	ABC transporter
MN187_08725	COG1285	pathogenesis
MN187_08745	COG0673	inositol 2-dehydrogenase activity
MN187_08750	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MN187_08755	COG1082	Xylose isomerase domain protein TIM barrel
MN187_08765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MN187_08775	COG1012	belongs to the aldehyde dehydrogenase family
MN187_08780	COG1349	DNA-binding transcription factor activity
MN187_08785	COG0552	protein localization to endoplasmic reticulum
MN187_08790	COG0561	phosphatase activity
MN187_08795	COG1196	nuclear chromosome segregation
MN187_08800	COG0571	ribonuclease III activity
MN187_08805	COG0747	negative chemotaxis
MN187_08810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MN187_08815	COG0601	transmembrane transport
MN187_08820	COG4608	Belongs to the ABC transporter superfamily
MN187_08830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MN187_08835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MN187_08840	COG0860	N-Acetylmuramoyl-L-alanine amidase
MN187_08845	COG3584	3D domain protein
MN187_08845	COG3583	domain protein
MN187_08860	COG1132	(ABC) transporter
MN187_08870	COG1011	Hydrolase
MN187_08875	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MN187_08880	COG1803	Methylglyoxal synthase
MN187_08885	COG3842	ATPase activity
MN187_08895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MN187_08900	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MN187_08905	COG0084	hydrolase, TatD family'
MN187_08910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN187_08910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN187_08915	COG4493	Belongs to the UPF0637 family
MN187_08945	COG1136	(ABC) transporter
MN187_08950	COG0463	Glycosyl transferase, family 2
MN187_08960	COG2246	polysaccharide biosynthetic process
MN187_08965	COG1737	Transcriptional regulator
MN187_08970	COG4607	ABC-type enterochelin transport system periplasmic component
MN187_08975	COG4604	ABC transporter, ATP-binding protein
MN187_08980	COG4605	iron ion homeostasis
MN187_08985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MN187_08995	COG1012	belongs to the aldehyde dehydrogenase family
MN187_09000	COG1181	Belongs to the D-alanine--D-alanine ligase family
MN187_09000	COG2918	glutathione biosynthetic process
MN187_09005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MN187_09005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MN187_09005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MN187_09010	COG1105	Belongs to the carbohydrate kinase PfkB family
MN187_09015	COG1349	DNA-binding transcription factor activity
MN187_09020	COG0018	arginyl-trna synthetase
MN187_09025	COG1288	antiporter activity
MN187_09030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MN187_09035	COG0549	Belongs to the carbamate kinase family
MN187_09040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MN187_09045	COG2235	arginine
MN187_09050	COG1438	arginine binding
MN187_09060	COG3684	Belongs to the aldolase LacD family
MN187_09065	COG2222	sugar isomerase
MN187_09070	COG2188	Transcriptional regulator
MN187_09100	COG3715	PTS system
MN187_09105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MN187_09110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MN187_09115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MN187_09115	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MN187_09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MN187_09130	COG0800	Aldolase
MN187_09140	COG1028	Short-chain dehydrogenase reductase Sdr
MN187_09145	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MN187_09155	COG2323	membrane
MN187_09205	COG1136	(ABC) transporter
MN187_09255	COG1447	Phosphotransferase system cellobiose-specific component IIA
MN187_09290	COG3579	cysteine-type endopeptidase activity
MN187_09300	COG1914	H( )-stimulated, divalent metal cation uptake system
MN187_09305	COG1028	Short-chain dehydrogenase reductase Sdr
MN187_09310	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MN187_09310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MN187_09315	COG3716	PTS system mannose fructose sorbose family IID component
MN187_09320	COG3715	PTS system
MN187_09335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MN187_09340	COG1304	FMN binding
MN187_09345	COG1346	cytolysis
MN187_09355	COG0583	DNA-binding transcription factor activity
MN187_09410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MN187_09415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MN187_09420	COG0101	tRNA pseudouridine synthase activity
MN187_09430	COG1122	ATPase activity
MN187_09435	COG1122	ATPase activity
MN187_09440	COG0203	ribosomal protein L17
MN187_09445	COG0202	RNA polymerase activity
MN187_09450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MN187_09455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MN187_09460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MN187_09465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MN187_09470	COG0563	adenylate kinase activity
MN187_09480	COG0200	Binds to the 23S rRNA
MN187_09485	COG1841	ribosomal large subunit assembly
MN187_09490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MN187_09500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MN187_09505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MN187_09510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MN187_09515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MN187_09520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MN187_09525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MN187_09530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MN187_09535	COG0255	Belongs to the universal ribosomal protein uL29 family
MN187_09540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MN187_09545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MN187_09550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MN187_09560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MN187_09565	COG0089	rRNA binding
MN187_09570	COG0088	Forms part of the polypeptide exit tunnel
MN187_09575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MN187_09580	COG0051	transcription antitermination factor activity, RNA binding
MN187_09585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MN187_09590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MN187_09595	COG0049	tRNA binding
MN187_09600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MN187_09605	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MN187_09610	COG0588	phosphoglycerate mutase activity
MN187_09615	COG1114	Component of the transport system for branched-chain amino acids
MN187_09820	COG1686	Belongs to the peptidase S11 family
MN187_09835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MN187_09840	COG0039	L-malate dehydrogenase activity
MN187_09850	COG0517	IMP dehydrogenase activity
MN187_09850	COG0516	GMP reductase activity
MN187_09860	COG0012	GTP binding
MN187_09865	COG4481	Protein conserved in bacteria
MN187_09870	COG1475	DNA binding
MN187_09875	COG1192	Involved in chromosome partitioning
MN187_09880	COG0357	Ribosomal RNA small subunit methyltransferase G
MN187_09890	COG0445	tRNA wobble uridine modification
MN187_09895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MN187_09905	COG0706	membrane insertase activity
MN187_09910	COG0594	ribonuclease P activity
MN187_09915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MN187_09920	COG1192	Involved in chromosome partitioning
MN187_09935	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_09960	COG5434	Belongs to the glycosyl hydrolase 28 family
MN187_09960	COG4632	Exopolysaccharide biosynthesis protein
MN187_10165	COG1061	Type III restriction enzyme res subunit
MN187_10205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MN187_10220	COG1192	Involved in chromosome partitioning
MN187_10235	COG1705	Flagellar rod assembly protein muramidase FlgJ
MN187_10370	COG1783	phage Terminase large subunit
MN187_10505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair