locus-tag	class	description
FA707_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FA707_00010	COG0592	DNA-directed DNA polymerase activity
FA707_00015	COG2501	S4 domain
FA707_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA707_00025	COG0187	DNA topoisomerase II activity
FA707_00035	COG0360	Binds together with S18 to 16S ribosomal RNA
FA707_00040	COG0629	single-stranded DNA binding
FA707_00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA707_00050	COG0359	binds to the 23S rRNA
FA707_00055	COG0305	Participates in initiation and elongation during chromosome replication
FA707_00060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA707_00065	COG1307	EDD domain protein, DegV family
FA707_00070	COG0488	(ABC) transporter
FA707_00075	COG0142	geranyltranstransferase activity
FA707_00135	COG3764	Sortase (surface protein transpeptidase)
FA707_00180	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FA707_00180	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FA707_00190	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FA707_00195	COG0295	cytidine deaminase activity
FA707_00200	COG1744	ABC transporter substrate-binding protein PnrA-like
FA707_00205	COG3845	ABC transporter
FA707_00210	COG4603	Belongs to the binding-protein-dependent transport system permease family
FA707_00215	COG1079	Belongs to the binding-protein-dependent transport system permease family
FA707_00220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FA707_00225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FA707_00230	COG0813	purine-nucleoside phosphorylase activity
FA707_00240	COG1278	Cold shock
FA707_00250	COG1132	(ABC) transporter
FA707_00255	COG1979	alcohol dehydrogenase
FA707_00270	COG0588	phosphoglycerate mutase activity
FA707_00275	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FA707_00280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA707_00285	COG0049	tRNA binding
FA707_00290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA707_00295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FA707_00305	COG0051	transcription antitermination factor activity, RNA binding
FA707_00310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA707_00315	COG0088	Forms part of the polypeptide exit tunnel
FA707_00320	COG0089	rRNA binding
FA707_00325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA707_00335	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FA707_00340	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA707_00345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA707_00350	COG0255	Belongs to the universal ribosomal protein uL29 family
FA707_00355	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA707_00360	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA707_00365	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FA707_00370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FA707_00375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FA707_00380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA707_00385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FA707_00390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA707_00395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA707_00400	COG1841	ribosomal large subunit assembly
FA707_00405	COG0200	Binds to the 23S rRNA
FA707_00410	COG0201	protein transport
FA707_00415	COG0563	adenylate kinase activity
FA707_00425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA707_00430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA707_00435	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA707_00440	COG0202	RNA polymerase activity
FA707_00445	COG0203	ribosomal protein L17
FA707_00450	COG1122	ATPase activity
FA707_00455	COG1122	ATPase activity
FA707_00470	COG2610	gluconate transmembrane transporter activity
FA707_00475	COG1929	Belongs to the glycerate kinase type-1 family
FA707_00480	COG3835	regulator
FA707_00485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA707_00490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA707_00505	COG1674	ftsk spoiiie
FA707_00555	COG1737	Transcriptional regulator
FA707_00560	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FA707_00565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA707_00570	COG0371	Dehydrogenase
FA707_00580	COG3716	PTS system mannose fructose sorbose family IID component
FA707_00600	COG1312	Catalyzes the dehydration of D-mannonate
FA707_00605	COG0800	Aldolase
FA707_00610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FA707_00620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA707_00625	COG0583	DNA-binding transcription factor activity
FA707_00630	COG0183	Belongs to the thiolase family
FA707_00635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FA707_00645	COG1028	Short-chain dehydrogenase reductase Sdr
FA707_00650	COG2610	gluconate transmembrane transporter activity
FA707_00655	COG2207	Transcriptional regulator
FA707_00680	COG0673	inositol 2-dehydrogenase activity
FA707_00685	COG0626	cystathionine gamma-synthase activity
FA707_00690	COG0251	oxidation-reduction process
FA707_00695	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA707_00710	COG0165	Argininosuccinate lyase
FA707_00715	COG0137	argininosuccinate synthase activity
FA707_00725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FA707_00735	COG2851	Citrate transporter
FA707_00745	COG0511	ligase activity, forming carbon-carbon bonds
FA707_00750	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FA707_00785	COG0281	malic enzyme
FA707_00790	COG3158	transport of potassium into the cell
FA707_00810	COG1349	DNA-binding transcription factor activity
FA707_00815	COG1105	Belongs to the carbohydrate kinase PfkB family
FA707_00820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FA707_00820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FA707_00820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA707_00825	COG0574	Belongs to the PEP-utilizing enzyme family
FA707_00825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA707_00830	COG0517	IMP dehydrogenase activity
FA707_00835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FA707_00840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA707_00850	COG2115	Belongs to the xylose isomerase family
FA707_00855	COG3507	Belongs to the glycosyl hydrolase 43 family
FA707_00860	COG1129	ABC transporter
FA707_00875	COG1070	Carbohydrate kinase
FA707_00900	COG2723	6-phospho-beta-galactosidase activity
FA707_00905	COG2190	(PTS) system
FA707_00905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_00905	COG1263	PTS System
FA707_00910	COG2188	Transcriptional regulator
FA707_00920	COG0494	nUDIX hydrolase
FA707_00925	COG4463	regulation of RNA biosynthetic process
FA707_00930	COG0542	response to heat
FA707_00935	COG0826	peptidase U32
FA707_00940	COG0826	peptidase U32
FA707_00945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FA707_00950	COG1271	oxidase subunit
FA707_00955	COG1294	oxidase, subunit
FA707_00960	COG4988	ABC transporter
FA707_00965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FA707_00975	COG0142	geranyltranstransferase activity
FA707_00985	COG0561	phosphatase activity
FA707_00995	COG0280	phosphate acetyltransferase
FA707_01015	COG0802	atpase or kinase
FA707_01025	COG3711	transcriptional antiterminator
FA707_01025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA707_01030	COG0604	alcohol dehydrogenase
FA707_01040	COG3842	ATPase activity
FA707_01045	COG1176	ABC-type spermidine putrescine transport system, permease component I
FA707_01050	COG1177	transmembrane transport
FA707_01055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FA707_01065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FA707_01070	COG3711	transcriptional antiterminator
FA707_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_01075	COG2190	(PTS) system
FA707_01075	COG1263	PTS System
FA707_01080	COG1692	metallophosphoesterase
FA707_01090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA707_01095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FA707_01100	COG0424	maF-like protein
FA707_01120	COG1968	undecaprenyl-diphosphatase activity
FA707_01130	COG0765	amino acid transport
FA707_01155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FA707_01160	COG1605	Chorismate mutase
FA707_01160	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FA707_01165	COG1476	TRANSCRIPTIONal
FA707_01180	COG1482	cell wall glycoprotein biosynthetic process
FA707_01190	COG0708	Exodeoxyribonuclease III
FA707_01195	COG2153	protein acetylation
FA707_01200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA707_01210	COG1278	Cold shock
FA707_01220	COG0459	protein refolding
FA707_01230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_01230	COG1263	PTS System
FA707_01235	COG0366	Alpha amylase catalytic
FA707_01240	COG2188	Transcriptional regulator
FA707_01250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FA707_01260	COG0516	GMP reductase activity
FA707_01265	COG1596	polysaccharide export
FA707_01265	COG1555	photosystem II stabilization
FA707_01270	COG2131	deaminase
FA707_01275	COG2333	competence protein COMEC
FA707_01275	COG0658	competence protein
FA707_01280	COG0514	ATP-dependent DNA helicase (RecQ)
FA707_01285	COG1466	dna polymerase III delta subunit
FA707_01305	COG0726	polysaccharide deacetylase
FA707_01310	COG0268	Binds directly to 16S ribosomal RNA
FA707_01315	COG0306	phosphate transporter
FA707_01320	COG1392	Phosphate transport regulator
FA707_01325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FA707_01345	COG1058	Belongs to the CinA family
FA707_01345	COG1546	Belongs to the CinA family
FA707_01350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA707_01355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA707_01365	COG1418	mRNA catabolic process
FA707_01370	COG1121	(ABC) transporter
FA707_01375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA707_01380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA707_01385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA707_01390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA707_01400	COG1970	mechanosensitive ion channel activity
FA707_01405	COG0612	Peptidase, M16
FA707_01410	COG0612	Peptidase, M16
FA707_01415	COG0300	oxidoreductase activity
FA707_01420	COG1426	Protein conserved in bacteria
FA707_01425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA707_01440	COG0561	phosphatase activity
FA707_01445	COG0745	RESPONSE REGULATOR receiver
FA707_01450	COG5002	protein histidine kinase activity
FA707_01450	COG3850	Histidine kinase
FA707_01455	COG4476	Belongs to the UPF0223 family
FA707_01460	COG0483	inositol monophosphate 1-phosphatase activity
FA707_01465	COG1217	gtp-binding protein TYPA
FA707_01470	COG2188	Transcriptional regulator
FA707_01485	COG3715	PTS system
FA707_01490	COG3716	PTS system mannose fructose sorbose family IID component
FA707_01500	COG2222	sugar isomerase
FA707_01505	COG3684	Belongs to the aldolase LacD family
FA707_01510	COG0191	fructose-bisphosphate aldolase activity
FA707_01520	COG2723	6-phospho-beta-galactosidase activity
FA707_01535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FA707_01540	COG1459	type II secretion system
FA707_01545	COG4537	Required for transformation and DNA binding
FA707_01570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA707_01570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA707_01575	COG0084	hydrolase, TatD family'
FA707_01580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FA707_01585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FA707_01590	COG1960	acyl-CoA dehydrogenase activity
FA707_01595	COG0583	DNA-binding transcription factor activity
FA707_01600	COG0183	Belongs to the thiolase family
FA707_01605	COG1960	acyl-CoA dehydrogenase activity
FA707_01610	COG1250	3-hydroxyacyl-CoA dehydrogenase
FA707_01615	COG1024	Enoyl-CoA hydratase
FA707_01620	COG0427	acetyl-CoA hydrolase
FA707_01625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FA707_01630	COG3842	ATPase activity
FA707_01645	COG1263	PTS System
FA707_01645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_01645	COG2190	(PTS) system
FA707_01655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FA707_01660	COG2017	converts alpha-aldose to the beta-anomer
FA707_01665	COG1609	Transcriptional regulator
FA707_01670	COG0366	Alpha amylase catalytic
FA707_01675	COG0366	Alpha amylase catalytic
FA707_01680	COG0366	Alpha amylase catalytic
FA707_01690	COG1175	transmembrane transport
FA707_01695	COG3833	ABC-type maltose transport systems, permease component
FA707_01715	COG1609	Transcriptional regulator
FA707_01720	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FA707_01725	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FA707_01730	COG2706	6-phosphogluconolactonase activity
FA707_01740	COG0628	permease
FA707_01745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FA707_01755	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_01755	COG3942	CHAP domain
FA707_01760	COG1368	sulfuric ester hydrolase activity
FA707_01765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FA707_01770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA707_01775	COG4716	Myosin-crossreactive antigen
FA707_01790	COG2081	HI0933 family
FA707_01795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA707_01800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FA707_01805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA707_01820	COG0166	Belongs to the GPI family
FA707_01825	COG0101	tRNA pseudouridine synthase activity
FA707_01830	COG0531	amino acid
FA707_01840	COG1611	Belongs to the LOG family
FA707_01845	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA707_01855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_01875	COG1121	(ABC) transporter
FA707_01880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA707_01885	COG0803	Belongs to the bacterial solute-binding protein 9 family
FA707_01890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA707_01895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA707_01900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA707_01905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA707_01910	COG0640	Transcriptional regulator
FA707_01915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FA707_01920	COG1376	ErfK ybiS ycfS ynhG family protein
FA707_01925	COG0431	NADPH-dependent FMN reductase
FA707_01935	COG1473	amidohydrolase
FA707_01940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA707_01950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA707_01955	COG1725	Transcriptional regulator
FA707_01960	COG1131	(ABC) transporter
FA707_01980	COG1136	(ABC) transporter
FA707_01980	COG0577	efflux transmembrane transporter activity
FA707_01985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA707_01990	COG2233	PERMEase
FA707_01995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA707_02015	COG1486	melibiose metabolic process
FA707_02025	COG0583	DNA-binding transcription factor activity
FA707_02035	COG1129	ABC transporter
FA707_02050	COG1113	amino acid transport
FA707_02055	COG1741	Belongs to the pirin family
FA707_02060	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA707_02065	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FA707_02070	COG1737	Transcriptional regulator
FA707_02080	COG0577	efflux transmembrane transporter activity
FA707_02085	COG1136	(ABC) transporter
FA707_02100	COG5002	protein histidine kinase activity
FA707_02100	COG3850	Histidine kinase
FA707_02115	COG1132	(ABC) transporter
FA707_02120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA707_02125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA707_02130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FA707_02140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FA707_02155	COG0716	FMN binding
FA707_02160	COG0561	phosphatase activity
FA707_02165	COG0346	lactoylglutathione lyase activity
FA707_02170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_02180	COG2723	6-phospho-beta-galactosidase activity
FA707_02200	COG0367	asparagine synthase
FA707_02210	COG0628	permease
FA707_02215	COG1253	flavin adenine dinucleotide binding
FA707_02230	COG1363	Peptidase, m42
FA707_02235	COG1234	tRNA 3'-trailer cleavage
FA707_02240	COG0095	Lipoate-protein ligase
FA707_02250	COG0180	Tryptophanyl-tRNA synthetase
FA707_02255	COG1393	Belongs to the ArsC family
FA707_02260	COG4862	establishment of competence for transformation
FA707_02265	COG1011	Hydrolase
FA707_02275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA707_02280	COG1780	Probably involved in ribonucleotide reductase function
FA707_02285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FA707_02305	COG0590	tRNA wobble adenosine to inosine editing
FA707_02330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA707_02335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FA707_02340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FA707_02345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FA707_02350	COG3870	Protein conserved in bacteria
FA707_02355	COG0470	DNA polymerase III
FA707_02360	COG1774	PSP1 C-terminal conserved region
FA707_02365	COG4467	Involved in initiation control of chromosome replication
FA707_02435	COG1278	Cold shock
FA707_02440	COG4948	Mandelate Racemase Muconate Lactonizing
FA707_02450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FA707_02455	COG1169	isochorismate synthase
FA707_02460	COG0318	PFAM AMP-dependent synthetase and ligase
FA707_02485	COG0318	PFAM AMP-dependent synthetase and ligase
FA707_02490	COG0531	amino acid
FA707_02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA707_02505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA707_02510	COG0768	penicillin binding
FA707_02515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA707_02525	COG1609	Transcriptional regulator
FA707_02535	COG1621	beta-fructofuranosidase activity
FA707_02540	COG1940	carbohydrate kinase activity
FA707_02550	COG0571	ribonuclease III activity
FA707_02555	COG1196	nuclear chromosome segregation
FA707_02560	COG0561	phosphatase activity
FA707_02565	COG0552	protein localization to endoplasmic reticulum
FA707_02595	COG0406	alpha-ribazole phosphatase activity
FA707_02600	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FA707_02600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FA707_02605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_02605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA707_02615	COG3715	PTS system
FA707_02620	COG3716	PTS system mannose fructose sorbose family IID component
FA707_02670	COG0006	proline dipeptidase activity
FA707_02675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA707_02680	COG1302	Protein conserved in bacteria
FA707_02685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA707_02690	COG1570	exodeoxyribonuclease VII activity
FA707_02695	COG1722	exodeoxyribonuclease VII activity
FA707_02705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FA707_02710	COG0497	DNA recombination
FA707_02720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FA707_02735	COG1610	YqeY-like protein
FA707_02770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA707_02780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA707_02790	COG1269	ATP hydrolysis coupled proton transport
FA707_02795	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA707_02800	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FA707_02805	COG1527	subunit (C
FA707_02810	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FA707_02815	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FA707_02820	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FA707_02825	COG1394	ATPase activity, coupled to movement of substances
FA707_02830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA707_02835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA707_02845	COG0705	Rhomboid family
FA707_02855	COG1940	carbohydrate kinase activity
FA707_02870	COG0542	response to heat
FA707_02880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA707_02885	COG0438	transferase activity, transferring glycosyl groups
FA707_02890	COG2084	Dehydrogenase
FA707_02905	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA707_02910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA707_02915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FA707_02920	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FA707_02925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FA707_02930	COG1534	Rna-binding protein
FA707_02935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FA707_02940	COG1713	HD superfamily hydrolase involved in NAD metabolism
FA707_02945	COG0799	negative regulation of ribosome biogenesis
FA707_02950	COG2226	methyltransferase
FA707_02960	COG0516	GMP reductase activity
FA707_02970	COG0351	phosphomethylpyrimidine kinase
FA707_02975	COG0351	phosphomethylpyrimidine kinase
FA707_02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA707_02990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA707_02995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA707_03000	COG2070	2-Nitropropane dioxygenase
FA707_03005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FA707_03010	COG1028	Short-chain dehydrogenase reductase Sdr
FA707_03015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA707_03030	COG0439	Biotin carboxylase
FA707_03035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA707_03040	COG0825	malonyl-CoA metabolic process
FA707_03060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FA707_03065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA707_03075	COG2217	Heavy metal translocating P-type atpase
FA707_03090	COG1595	DNA-templated transcription, initiation
FA707_03125	COG1105	Belongs to the carbohydrate kinase PfkB family
FA707_03130	COG1214	PFAM Peptidase M22, glycoprotease
FA707_03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FA707_03155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA707_03180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FA707_03185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FA707_03195	COG4585	Histidine kinase
FA707_03200	COG2197	response regulator
FA707_03205	COG0569	domain protein
FA707_03210	COG4841	protein insertion into membrane
FA707_03220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FA707_03225	COG4838	Belongs to the UPF0358 family
FA707_03230	COG0772	Belongs to the SEDS family
FA707_03235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FA707_03245	COG3679	Belongs to the UPF0342 family
FA707_03250	COG4471	UPF0298 protein
FA707_03255	COG0742	ribosomal rna small subunit methyltransferase
FA707_03260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FA707_03265	COG3480	Lon protease (S16) C-terminal proteolytic domain
FA707_03270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA707_03285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FA707_03295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA707_03295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA707_03300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FA707_03305	COG0237	dephospho-CoA kinase activity
FA707_03310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA707_03320	COG1484	DNA-dependent DNA replication
FA707_03330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA707_03335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FA707_03340	COG0745	RESPONSE REGULATOR receiver
FA707_03345	COG5002	protein histidine kinase activity
FA707_03355	COG0706	membrane insertase activity
FA707_03360	COG1254	Belongs to the acylphosphatase family
FA707_03365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA707_03375	COG1733	regulation of RNA biosynthetic process
FA707_03380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA707_03385	COG0072	phenylalanine-tRNA ligase activity
FA707_03385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA707_03400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FA707_03405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FA707_03425	COG0640	Transcriptional regulator
FA707_03440	COG1950	PFAM Membrane protein of
FA707_03445	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FA707_03465	COG1253	flavin adenine dinucleotide binding
FA707_03480	COG2723	6-phospho-beta-galactosidase activity
FA707_03495	COG0671	phosphoesterase, PA-phosphatase related
FA707_03500	COG2076	Multidrug Resistance protein
FA707_03505	COG2076	Multidrug Resistance protein
FA707_03515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA707_03525	COG0531	amino acid
FA707_03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_03540	COG1263	PTS System
FA707_03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA707_03560	COG0281	malic enzyme
FA707_03570	COG3594	Acyltransferase
FA707_03585	COG1126	abc transporter atp-binding protein
FA707_03590	COG0765	amino acid transport
FA707_03595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA707_03600	COG4485	Bacterial membrane protein, YfhO
FA707_03610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA707_03615	COG1435	thymidine kinase activity
FA707_03620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA707_03625	COG2890	protein-(glutamine-N5) methyltransferase activity
FA707_03630	COG0009	L-threonylcarbamoyladenylate synthase
FA707_03635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA707_03640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA707_03645	COG0772	Belongs to the SEDS family
FA707_03650	COG1132	(ABC) transporter
FA707_03655	COG1132	(ABC) transporter
FA707_03660	COG2188	Transcriptional regulator
FA707_03670	COG3964	amidohydrolase
FA707_03685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FA707_03705	COG0105	UTP biosynthetic process
FA707_03710	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FA707_03735	COG0039	L-malate dehydrogenase activity
FA707_03745	COG0745	RESPONSE REGULATOR receiver
FA707_03750	COG5002	protein histidine kinase activity
FA707_03760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FA707_03770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FA707_03775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA707_03780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FA707_03790	COG1307	EDD domain protein, DegV family
FA707_03800	COG0587	DNA-directed DNA polymerase activity
FA707_03805	COG0205	6-phosphofructokinase activity
FA707_03815	COG3409	Peptidoglycan-binding domain 1 protein
FA707_03815	COG0793	Belongs to the peptidase S41A family
FA707_03825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FA707_03830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA707_03835	COG0758	DNA mediated transformation
FA707_03840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA707_03845	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FA707_03850	COG4974	Belongs to the 'phage' integrase family
FA707_03855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FA707_03860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FA707_03870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA707_03875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA707_03880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FA707_03895	COG0556	nucleotide-excision repair
FA707_03900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA707_03905	COG1660	Displays ATPase and GTPase activities
FA707_03915	COG1481	regulation of sporulation
FA707_03925	COG0740	serine-type endopeptidase activity
FA707_03940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA707_03950	COG0557	exoribonuclease II activity
FA707_03955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA707_03960	COG0356	it plays a direct role in the translocation of protons across the membrane
FA707_03965	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA707_03970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FA707_03975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA707_03980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FA707_03985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA707_03990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FA707_03995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FA707_04005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA707_04015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FA707_04050	COG4209	transmembrane transport
FA707_04055	COG0395	ABC-type sugar transport system, permease component
FA707_04065	COG4209	transmembrane transport
FA707_04070	COG0395	ABC-type sugar transport system, permease component
FA707_04085	COG2207	Transcriptional regulator
FA707_04095	COG1472	Belongs to the glycosyl hydrolase 3 family
FA707_04100	COG2723	6-phospho-beta-galactosidase activity
FA707_04110	COG1446	asparaginase
FA707_04115	COG3250	beta-galactosidase activity
FA707_04120	COG3291	Pkd domain containing protein
FA707_04120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FA707_04135	COG3408	Glycogen debranching enzyme
FA707_04135	COG3119	arylsulfatase activity
FA707_04140	COG0641	radical SAM
FA707_04150	COG1175	transmembrane transport
FA707_04155	COG0395	ABC-type sugar transport system, permease component
FA707_04160	COG1653	transport
FA707_04170	COG2972	Histidine kinase
FA707_04175	COG2207	Transcriptional regulator
FA707_04175	COG4753	response regulator
FA707_04185	COG1609	Transcriptional regulator
FA707_04195	COG0383	alpha-mannosidase activity
FA707_04200	COG1940	carbohydrate kinase activity
FA707_04225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FA707_04230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FA707_04235	COG0546	phosphoglycolate phosphatase activity
FA707_04240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FA707_04245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FA707_04255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FA707_04275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FA707_04280	COG1074	ATP-dependent DNA helicase activity
FA707_04300	COG0217	transcriptional regulatory protein
FA707_04315	COG2261	transglycosylase associated protein
FA707_04320	COG0778	Nitroreductase
FA707_04325	COG0504	CTP synthase activity
FA707_04340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FA707_04345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FA707_04350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA707_04355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA707_04360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA707_04365	COG4684	Psort location CytoplasmicMembrane, score
FA707_04370	COG1309	transcriptional regulator
FA707_04375	COG0187	DNA topoisomerase II activity
FA707_04380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FA707_04395	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FA707_04400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FA707_04410	COG0228	four-way junction DNA binding
FA707_04415	COG1846	Transcriptional regulator
FA707_04415	COG0456	acetyltransferase
FA707_04420	COG2321	neutral zinc metallopeptidase
FA707_04455	COG1136	(ABC) transporter
FA707_04465	COG1428	Deoxynucleoside kinase
FA707_04470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FA707_04475	COG1882	Formate acetyltransferase
FA707_04480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FA707_04485	COG1027	Aspartate ammonia-lyase
FA707_04490	COG1227	inorganic diphosphatase activity
FA707_04500	COG3442	glutamine amidotransferase
FA707_04505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA707_04510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA707_04525	COG2608	mercury ion transmembrane transporter activity
FA707_04530	COG2217	Heavy metal translocating P-type atpase
FA707_04535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FA707_04540	COG0336	Belongs to the RNA methyltransferase TrmD family
FA707_04545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FA707_04550	COG0584	glycerophosphoryl diester phosphodiesterase
FA707_04555	COG0335	large ribosomal subunit rRNA binding
FA707_04565	COG4372	Transposase
FA707_04645	COG4372	Transposase
FA707_04670	COG2207	Transcriptional regulator
FA707_04680	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FA707_04685	COG2376	Dihydroxyacetone kinase
FA707_04690	COG1461	Dihydroxyacetone kinase
FA707_04715	COG4894	glucomannan catabolic process
FA707_04720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA707_04730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA707_04735	COG2151	metal-sulfur cluster biosynthetic enzyme
FA707_04740	COG4974	Belongs to the 'phage' integrase family
FA707_04765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FA707_04775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA707_04855	COG0582	viral genome integration into host DNA
FA707_04870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA707_04880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA707_04885	COG2151	metal-sulfur cluster biosynthetic enzyme
FA707_04895	COG2268	Band 7 protein
FA707_04910	COG2723	6-phospho-beta-galactosidase activity
FA707_04915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FA707_04915	COG1199	ATP-dependent helicase activity
FA707_04925	COG0436	Aminotransferase
FA707_04935	COG1725	Transcriptional regulator
FA707_04940	COG1131	(ABC) transporter
FA707_04950	COG0577	efflux transmembrane transporter activity
FA707_04955	COG1136	(ABC) transporter
FA707_04965	COG0358	DNA primase activity
FA707_04970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA707_04975	COG0710	3-dehydroquinate dehydratase activity
FA707_04980	COG2384	SAM-dependent methyltransferase
FA707_04985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA707_04990	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA707_05005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA707_05020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA707_05025	COG3763	UPF0154 protein
FA707_05030	COG1132	(ABC) transporter
FA707_05035	COG1132	(ABC) transporter
FA707_05040	COG0534	Mate efflux family protein
FA707_05045	COG0492	ferredoxin-NADP+ reductase activity
FA707_05050	COG1323	Belongs to the UPF0348 family
FA707_05055	COG1136	(ABC) transporter
FA707_05065	COG0228	four-way junction DNA binding
FA707_05070	COG1837	Belongs to the UPF0109 family
FA707_05085	COG2814	Major facilitator Superfamily
FA707_05095	COG2723	6-phospho-beta-galactosidase activity
FA707_05100	COG2188	Transcriptional regulator
FA707_05105	COG2267	carboxylic ester hydrolase activity
FA707_05110	COG1304	FMN binding
FA707_05135	COG3425	synthase
FA707_05140	COG1846	Transcriptional regulator
FA707_05145	COG0346	lactoylglutathione lyase activity
FA707_05150	COG0346	lactoylglutathione lyase activity
FA707_05155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FA707_05165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA707_05175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA707_05180	COG1234	tRNA 3'-trailer cleavage
FA707_05185	COG0300	oxidoreductase activity
FA707_05195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FA707_05195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FA707_05200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA707_05210	COG3935	DnaD domain protein
FA707_05215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FA707_05220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA707_05225	COG3331	DNA recombination
FA707_05230	COG4474	Belongs to the UPF0398 family
FA707_05235	COG3599	regulation of cell shape
FA707_05245	COG0116	Belongs to the methyltransferase superfamily
FA707_05250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FA707_05255	COG1288	antiporter activity
FA707_05265	COG1307	EDD domain protein, DegV family
FA707_05275	COG0328	RNA-DNA hybrid ribonuclease activity
FA707_05285	COG1278	Cold shock
FA707_05300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA707_05305	COG0564	pseudouridine synthase activity
FA707_05310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FA707_05320	COG0540	Belongs to the ATCase OTCase family
FA707_05325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA707_05330	COG0505	Belongs to the CarA family
FA707_05335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA707_05340	COG0543	2 iron, 2 sulfur cluster binding
FA707_05345	COG0167	dihydroorotate dehydrogenase activity
FA707_05350	COG0284	orotidine-5'-phosphate decarboxylase activity
FA707_05365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FA707_05370	COG0745	RESPONSE REGULATOR receiver
FA707_05375	COG5002	protein histidine kinase activity
FA707_05380	COG1942	4-Oxalocrotonate Tautomerase
FA707_05390	COG4656	Part of a membrane complex involved in electron transport
FA707_05395	COG0252	asparaginase activity
FA707_05395	COG5275	peptidyl-tyrosine sulfation
FA707_05415	COG0252	asparaginase activity
FA707_05415	COG5275	peptidyl-tyrosine sulfation
FA707_05430	COG0709	Synthesizes selenophosphate from selenide and ATP
FA707_05455	COG1921	L-seryl-tRNASec selenium transferase activity
FA707_05460	COG2391	methyltransferase activity
FA707_05465	COG0425	Belongs to the sulfur carrier protein TusA family
FA707_05475	COG4974	Belongs to the 'phage' integrase family
FA707_05490	COG1012	belongs to the aldehyde dehydrogenase family
FA707_05500	COG4607	ABC-type enterochelin transport system periplasmic component
FA707_05505	COG4604	ABC transporter, ATP-binding protein
FA707_05510	COG4605	iron ion homeostasis
FA707_05515	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FA707_05525	COG4479	Belongs to the UPF0346 family
FA707_05530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA707_05540	COG2755	lipolytic protein G-D-S-L family
FA707_05545	COG1307	EDD domain protein, DegV family
FA707_05550	COG1272	protein, Hemolysin III
FA707_05565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA707_05570	COG1803	Methylglyoxal synthase
FA707_05575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FA707_05585	COG0488	(ABC) transporter
FA707_05600	COG0617	tRNA 3'-terminal CCA addition
FA707_05605	COG1694	Mazg nucleotide pyrophosphohydrolase
FA707_05610	COG5582	Belongs to the UPF0302 family
FA707_05630	COG1160	GTP binding
FA707_05635	COG0539	negative regulation of cytoplasmic translation
FA707_05640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FA707_05650	COG0514	ATP-dependent DNA helicase (RecQ)
FA707_05665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FA707_05670	COG1187	pseudouridine synthase activity
FA707_05675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FA707_05680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FA707_05690	COG0735	belongs to the Fur family
FA707_05700	COG2996	Protein conserved in bacteria
FA707_05705	COG2252	PERMEase
FA707_05710	COG1914	H( )-stimulated, divalent metal cation uptake system
FA707_05745	COG1473	amidohydrolase
FA707_05750	COG1464	Belongs to the NlpA lipoprotein family
FA707_05755	COG2011	ABC-type metal ion transport system permease component
FA707_05760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA707_05780	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FA707_05785	COG0149	triose-phosphate isomerase activity
FA707_05790	COG0126	phosphoglycerate kinase activity
FA707_05795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA707_05805	COG0038	chloride channel
FA707_05810	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA707_05840	COG0673	inositol 2-dehydrogenase activity
FA707_05850	COG1136	(ABC) transporter
FA707_05860	COG1309	transcriptional regulator
FA707_05875	COG1609	Transcriptional regulator
FA707_05885	COG0484	heat shock protein binding
FA707_05890	COG0443	Heat shock 70 kDa protein
FA707_05895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FA707_05900	COG1420	regulation of RNA biosynthetic process
FA707_05905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA707_05910	COG0196	riboflavin kinase activity
FA707_05915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FA707_05920	COG2814	Major facilitator Superfamily
FA707_05925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FA707_05940	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FA707_05945	COG0195	Participates in both transcription termination and antitermination
FA707_05950	COG0779	Required for maturation of 30S ribosomal subunits
FA707_05955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA707_05960	COG2116	formate transmembrane transporter activity
FA707_05965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FA707_05975	COG1040	competence protein
FA707_05980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FA707_05985	COG2267	carboxylic ester hydrolase activity
FA707_05995	COG1739	Uncharacterized protein family UPF0029
FA707_06000	COG2188	Transcriptional regulator
FA707_06010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA707_06025	COG0668	transmembrane transport
FA707_06035	COG3404	Formiminotransferase-cyclodeaminase
FA707_06040	COG0151	Belongs to the GarS family
FA707_06050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FA707_06055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FA707_06065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA707_06070	COG0047	phosphoribosylformylglycinamidine synthase activity
FA707_06075	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA707_06080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA707_06085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA707_06095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA707_06100	COG0704	Plays a role in the regulation of phosphate uptake
FA707_06105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA707_06110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA707_06115	COG0581	inorganic phosphate transmembrane transporter activity
FA707_06120	COG0573	inorganic phosphate transmembrane transporter activity
FA707_06125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FA707_06130	COG2177	Part of the ABC transporter FtsEX involved in
FA707_06135	COG2884	Cell division ATP-binding protein ftsE
FA707_06145	COG0653	protein targeting
FA707_06150	COG0481	GTPase activity
FA707_06155	COG0542	response to heat
FA707_06170	COG0751	glycine-tRNA ligase activity
FA707_06175	COG0752	glycyl-tRNA synthetase alpha subunit
FA707_06180	COG1381	Involved in DNA repair and RecF pathway recombination
FA707_06185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FA707_06190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FA707_06195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FA707_06205	COG1702	phosphate starvation-inducible protein PhoH
FA707_06210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA707_06215	COG0025	NhaP-type Na H and K H
FA707_06225	COG0183	Belongs to the thiolase family
FA707_06240	COG1674	ftsk spoiiie
FA707_06240	COG1280	lysine exporter protein (LysE YggA)
FA707_06250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA707_06250	COG0551	DNA topoisomerase type I activity
FA707_06260	COG1464	Belongs to the NlpA lipoprotein family
FA707_06265	COG2011	ABC-type metal ion transport system permease component
FA707_06270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA707_06275	COG0509	glycine decarboxylation via glycine cleavage system
FA707_06280	COG1393	Belongs to the ArsC family
FA707_06300	COG0534	Mate efflux family protein
FA707_06315	COG0656	L-ascorbic acid biosynthetic process
FA707_06320	COG1757	Na H antiporter
FA707_06325	COG2502	aspartate--ammonia ligase
FA707_06340	COG1131	(ABC) transporter
FA707_06365	COG2261	transglycosylase associated protein
FA707_06390	COG2723	6-phospho-beta-galactosidase activity
FA707_06395	COG2723	6-phospho-beta-galactosidase activity
FA707_06400	COG1447	Phosphotransferase system cellobiose-specific component IIA
FA707_06405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_06405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_06415	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FA707_06415	COG3711	transcriptional antiterminator
FA707_06435	COG3421	Type III restriction
FA707_06440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FA707_06490	COG0582	viral genome integration into host DNA
FA707_06495	COG1619	proteins homologs of microcin C7 resistance protein MccF
FA707_06500	COG0719	Fe-S assembly protein
FA707_06510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FA707_06515	COG0719	Fe-S assembly protein
FA707_06525	COG1132	(ABC) transporter
FA707_06530	COG1132	(ABC) transporter
FA707_06535	COG0482	sulfurtransferase activity
FA707_06540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FA707_06555	COG1104	cysteine desulfurase activity
FA707_06560	COG0768	penicillin binding
FA707_06565	COG1879	ABC-type sugar transport system periplasmic component
FA707_06570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FA707_06580	COG1869	D-ribose catabolic process
FA707_06585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FA707_06590	COG1609	Transcriptional regulator
FA707_06595	COG1335	isochorismatase
FA707_06600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA707_06620	COG3853	Toxic anion resistance protein (TelA)
FA707_06630	COG1114	Component of the transport system for branched-chain amino acids
FA707_06635	COG0508	dehydrogenase complex catalyzes the overall conversion of
FA707_06640	COG0022	dehydrogenase e1 component
FA707_06645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FA707_06650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FA707_06655	COG3426	butyrate kinase activity
FA707_06660	COG0280	phosphate acetyltransferase
FA707_06670	COG1196	nuclear chromosome segregation
FA707_06670	COG0741	lytic transglycosylase activity
FA707_06670	COG0739	heme binding
FA707_06680	COG1181	Belongs to the D-alanine--D-alanine ligase family
FA707_06680	COG2918	glutathione biosynthetic process
FA707_06720	COG0601	transmembrane transport
FA707_06725	COG4608	Belongs to the ABC transporter superfamily
FA707_06735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA707_06740	COG0416	fatty acid biosynthetic process
FA707_06745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FA707_06760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FA707_06765	COG1564	THIamine pyrophosphokinase
FA707_06770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA707_06775	COG1162	GTPase activity
FA707_06780	COG2815	serine threonine protein kinase
FA707_06780	COG0515	serine threonine protein kinase
FA707_06785	COG0631	protein serine/threonine phosphatase activity
FA707_06790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA707_06790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FA707_06795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FA707_06800	COG0242	peptide deformylase activity
FA707_06805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FA707_06815	COG0194	GDP metabolic process
FA707_06820	COG1561	YicC-like family, N-terminal region
FA707_06825	COG4443	Transcriptional Coactivator p15 (PC4)
FA707_06840	COG0736	holo-[acyl-carrier-protein] synthase activity
FA707_06850	COG3279	Response regulator of the LytR AlgR family
FA707_06860	COG3290	protein histidine kinase activity
FA707_06870	COG1131	(ABC) transporter
FA707_06880	COG1131	(ABC) transporter
FA707_06900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA707_06905	COG1181	Belongs to the D-alanine--D-alanine ligase family
FA707_06915	COG3764	Sortase (surface protein transpeptidase)
FA707_06980	COG1136	(ABC) transporter
FA707_06985	COG0577	efflux transmembrane transporter activity
FA707_06995	COG3942	CHAP domain
FA707_06995	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_07015	COG0681	Belongs to the peptidase S26 family
FA707_07020	COG1388	LysM domain
FA707_07020	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_07025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA707_07035	COG0495	leucyl-tRNA aminoacylation
FA707_07040	COG1388	LysM domain
FA707_07040	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_07055	COG0671	phosphoesterase, PA-phosphatase related
FA707_07060	COG1242	4 iron, 4 sulfur cluster binding
FA707_07065	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FA707_07070	COG0477	Major facilitator Superfamily
FA707_07080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA707_07090	COG0222	ribosome binding
FA707_07095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA707_07100	COG0081	regulation of translation
FA707_07105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA707_07115	COG0250	Participates in transcription elongation, termination and antitermination
FA707_07125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA707_07135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA707_07140	COG3599	regulation of cell shape
FA707_07145	COG2302	S4 RNA-binding domain
FA707_07155	COG1799	cell septum assembly
FA707_07160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA707_07165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA707_07170	COG0849	cell division
FA707_07175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FA707_07180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA707_07185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA707_07195	COG0768	penicillin binding
FA707_07205	COG0275	rRNA processing
FA707_07210	COG2001	Belongs to the MraZ family
FA707_07250	COG1098	S1 RNA binding domain
FA707_07260	COG0492	ferredoxin-NADP+ reductase activity
FA707_07265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FA707_07275	COG0647	UMP catabolic process
FA707_07280	COG4470	Protein conserved in bacteria
FA707_07285	COG0737	Belongs to the 5'-nucleotidase family
FA707_07290	COG2365	Tyrosine phosphatase family
FA707_07295	COG0783	Belongs to the Dps family
FA707_07300	COG3118	belongs to the thioredoxin family
FA707_07305	COG1193	negative regulation of DNA recombination
FA707_07315	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FA707_07320	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA707_07335	COG3906	Belongs to the UPF0473 family
FA707_07345	COG4472	Bacterial protein of unknown function (DUF965)
FA707_07350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA707_07355	COG0589	response to stress
FA707_07360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA707_07365	COG1363	Peptidase, m42
FA707_07375	COG1464	Belongs to the NlpA lipoprotein family
FA707_07380	COG2011	ABC-type metal ion transport system permease component
FA707_07385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA707_07390	COG1132	(ABC) transporter
FA707_07405	COG0510	thiamine kinase activity
FA707_07410	COG4473	ABC transporter
FA707_07415	COG1131	(ABC) transporter
FA707_07420	COG0537	adenosine 5'-monophosphoramidase activity
FA707_07430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA707_07435	COG3481	metal-dependent phosphohydrolase, HD sub domain
FA707_07440	COG4717	serine-type aminopeptidase activity
FA707_07450	COG3679	Belongs to the UPF0342 family
FA707_07455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FA707_07460	COG0564	pseudouridine synthase activity
FA707_07465	COG0018	arginyl-trna synthetase
FA707_07485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA707_07495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA707_07505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FA707_07515	COG2910	NAD(P)H-binding
FA707_07520	COG3091	SprT-like family
FA707_07525	COG2183	response to ionizing radiation
FA707_07540	COG1288	antiporter activity
FA707_07545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FA707_07550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA707_07555	COG1126	abc transporter atp-binding protein
FA707_07560	COG0765	amino acid transport
FA707_07570	COG2814	Major facilitator Superfamily
FA707_07580	COG1132	(ABC) transporter
FA707_07605	COG4989	oxidoreductase activity
FA707_07610	COG1802	Transcriptional regulator
FA707_07615	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FA707_07620	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_07625	COG1876	peptidase activity
FA707_07635	COG4129	membrane
FA707_07665	COG0095	Lipoate-protein ligase
FA707_07670	COG1078	dGTPase activity
FA707_07675	COG0561	phosphatase activity
FA707_07680	COG0346	lactoylglutathione lyase activity
FA707_07705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FA707_07710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA707_07720	COG4493	Belongs to the UPF0637 family
FA707_07725	COG0519	Catalyzes the synthesis of GMP from XMP
FA707_07730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA707_07735	COG1597	lipid kinase activity
FA707_07740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA707_07745	COG0154	amidase activity
FA707_07750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA707_07760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA707_07765	COG0210	DNA helicase
FA707_07775	COG0322	excinuclease ABC activity
FA707_07790	COG1288	antiporter activity
FA707_07800	COG0549	Belongs to the carbamate kinase family
FA707_07805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA707_07810	COG2235	arginine
FA707_07815	COG0442	prolyl-tRNA aminoacylation
FA707_07820	COG0750	zinc metalloprotease
FA707_07825	COG4589	Belongs to the CDS family
FA707_07830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA707_07870	COG0233	cytoplasmic translational termination
FA707_07875	COG0528	UMP kinase activity
FA707_07880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA707_07885	COG0052	Belongs to the universal ribosomal protein uS2 family
FA707_07890	COG2813	Specifically methylates the guanine in position
FA707_07905	COG1072	(Pantothenic acid kinase))
FA707_07910	COG0519	Catalyzes the synthesis of GMP from XMP
FA707_07910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA707_07955	COG4974	Belongs to the 'phage' integrase family
FA707_07965	COG0556	nucleotide-excision repair
FA707_07990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FA707_08005	COG1136	(ABC) transporter
FA707_08010	COG0642	Histidine kinase
FA707_08015	COG0745	RESPONSE REGULATOR receiver
FA707_08020	COG2207	Transcriptional regulator
FA707_08020	COG3708	Transcriptional regulator
FA707_08085	COG3711	transcriptional antiterminator
FA707_08095	COG1252	NADH dehydrogenase
FA707_08110	COG1473	amidohydrolase
FA707_08120	COG2388	GCN5-related N-acetyl-transferase
FA707_08155	COG2390	Transcriptional regulator
FA707_08165	COG1917	Cupin 2, conserved barrel domain protein
FA707_08170	COG1185	polyribonucleotide nucleotidyltransferase activity
FA707_08175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA707_08185	COG0242	peptide deformylase activity
FA707_08195	COG1346	cytolysis
FA707_08200	COG1380	Effector of murein hydrolase LrgA
FA707_08205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FA707_08225	COG0436	Aminotransferase
FA707_08240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FA707_08245	COG3428	Bacterial PH domain
FA707_08250	COG3402	PFAM membrane-flanked domain
FA707_08255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA707_08260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA707_08265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA707_08270	COG0124	histidyl-tRNA synthetase
FA707_08275	COG4991	sh3 domain protein
FA707_08275	COG3103	Sh3 type 3 domain protein
FA707_08275	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA707_08280	COG1490	D-aminoacyl-tRNA deacylase activity
FA707_08285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA707_08290	COG1442	glycosyl transferase family 8
FA707_08295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FA707_08300	COG2264	protein methyltransferase activity
FA707_08315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FA707_08330	COG0589	response to stress
FA707_08340	COG0531	amino acid
FA707_08360	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_08360	COG1388	LysM domain
FA707_08370	COG0789	Transcriptional regulator
FA707_08375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FA707_08385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FA707_08390	COG1132	(ABC) transporter
FA707_08395	COG1132	(ABC) transporter
FA707_08410	COG0604	alcohol dehydrogenase
FA707_08415	COG0659	secondary active sulfate transmembrane transporter activity
FA707_08420	COG3557	Belongs to the UPF0374 family
FA707_08430	COG1194	a g-specific adenine glycosylase
FA707_08435	COG2137	regulation of response to DNA damage stimulus
FA707_08470	COG3250	beta-galactosidase activity
FA707_08480	COG3833	ABC-type maltose transport systems, permease component
FA707_08485	COG1175	transmembrane transport
FA707_08505	COG1316	TRANSCRIPTIONal
FA707_08510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FA707_08515	COG0728	peptidoglycan biosynthetic process
FA707_08530	COG1091	dTDP-4-dehydrorhamnose reductase activity
FA707_08535	COG1088	dTDP-glucose 4,6-dehydratase activity
FA707_08545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA707_08565	COG0438	transferase activity, transferring glycosyl groups
FA707_08585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FA707_08595	COG4464	protein tyrosine phosphatase activity
FA707_08600	COG0489	protein tyrosine kinase activity
FA707_08605	COG3944	biosynthesis protein
FA707_08640	COG4886	Leucine-rich repeat (LRR) protein
FA707_08660	COG0463	Glycosyl transferase, family 2
FA707_08665	COG2246	polysaccharide biosynthetic process
FA707_08680	COG0463	Glycosyl transferase, family 2
FA707_08680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FA707_08690	COG1705	Flagellar rod assembly protein muramidase FlgJ
FA707_08690	COG1388	LysM domain
FA707_08715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FA707_08720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FA707_08735	COG1682	transport, permease protein
FA707_08740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FA707_08745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FA707_08750	COG1134	teichoic acid transport
FA707_08755	COG1316	TRANSCRIPTIONal
FA707_08760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA707_08765	COG1295	ribonuclease BN
FA707_08770	COG0024	Methionine aminopeptidase
FA707_08775	COG0716	FMN binding
FA707_08785	COG2309	aminopeptidase activity
FA707_08815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_08820	COG1447	Phosphotransferase system cellobiose-specific component IIA
FA707_08825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_08840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_08860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_08865	COG1447	Phosphotransferase system cellobiose-specific component IIA
FA707_08870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FA707_08875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FA707_08875	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FA707_08880	COG0513	Belongs to the DEAD box helicase family
FA707_08885	COG0673	inositol 2-dehydrogenase activity
FA707_08900	COG0765	amino acid transport
FA707_08905	COG1132	(ABC) transporter
FA707_08915	COG5503	Protein of unknown function (DUF1447)
FA707_08930	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FA707_08935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FA707_08940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FA707_08945	COG0584	glycerophosphoryl diester phosphodiesterase
FA707_08955	COG1278	Cold shock
FA707_08960	COG2003	Belongs to the UPF0758 family
FA707_08970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FA707_08975	COG0285	dihydrofolate synthase activity
FA707_08980	COG0525	valine-tRNA ligase activity
FA707_08995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FA707_09000	COG0301	tRNA thio-modification
FA707_09005	COG1104	cysteine desulfurase activity
FA707_09010	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FA707_09020	COG1801	Protein of unknown function DUF72
FA707_09030	COG2514	catechol 2,3-dioxygenase activity
FA707_09035	COG4466	Protein conserved in bacteria
FA707_09190	COG0735	belongs to the Fur family
FA707_09200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA707_09205	COG2176	DNA-directed DNA polymerase activity
FA707_09210	COG1268	BioY protein
FA707_09245	COG0582	viral genome integration into host DNA
FA707_09325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FA707_09330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA707_09335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FA707_09345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FA707_09350	COG0037	tRNA processing
FA707_09355	COG1098	S1 RNA binding domain
FA707_09365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FA707_09370	COG2244	polysaccharide biosynthetic process
FA707_09375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FA707_09380	COG0193	aminoacyl-tRNA hydrolase activity
FA707_09395	COG2738	Putative neutral zinc metallopeptidase
FA707_09400	COG2824	Alkylphosphonate utilization operon protein PhnA
FA707_09415	COG1368	sulfuric ester hydrolase activity
FA707_09425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FA707_09430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FA707_09440	COG3142	Participates in the control of copper homeostasis
FA707_09445	COG2239	Acts as a magnesium transporter
FA707_09450	COG0564	pseudouridine synthase activity
FA707_09455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA707_09460	COG2357	RelA SpoT domain protein
FA707_09465	COG4116	CYTH
FA707_09475	COG0601	transmembrane transport
FA707_09480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA707_09485	COG0444	Belongs to the ABC transporter superfamily
FA707_09490	COG4608	Belongs to the ABC transporter superfamily
FA707_09500	COG0737	Belongs to the 5'-nucleotidase family
FA707_09540	COG1792	Involved in formation and maintenance of cell shape
FA707_09545	COG1454	alcohol dehydrogenase
FA707_09545	COG1012	belongs to the aldehyde dehydrogenase family
FA707_09550	COG1862	Preprotein translocase
FA707_09555	COG0343	queuine tRNA-ribosyltransferase activity
FA707_09560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FA707_09565	COG2255	four-way junction helicase activity
FA707_09575	COG3325	Belongs to the glycosyl hydrolase 18 family
FA707_09575	COG3469	chitinase activity
FA707_09590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FA707_09615	COG2207	Transcriptional regulator
FA707_09630	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FA707_09640	COG0475	glutathione-regulated potassium exporter activity
FA707_09645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA707_09650	COG0827	DNA restriction-modification system
FA707_09655	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FA707_09660	COG3104	oligopeptide transport
FA707_09675	COG1668	transmembrane transport
FA707_09680	COG4152	abc transporter atp-binding protein
FA707_09685	COG2723	6-phospho-beta-galactosidase activity
FA707_09690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FA707_09690	COG1263	PTS System
FA707_09690	COG2190	(PTS) system
FA707_09695	COG3711	transcriptional antiterminator
FA707_09705	COG0561	phosphatase activity
FA707_09720	COG2814	Major facilitator Superfamily
FA707_09725	COG1846	Transcriptional regulator
FA707_09735	COG1028	Short-chain dehydrogenase reductase Sdr
FA707_09745	COG0861	Integral membrane protein TerC family
FA707_09770	COG2252	PERMEase
FA707_09785	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FA707_09790	COG1518	maintenance of DNA repeat elements
FA707_09795	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FA707_09805	COG1215	transferase activity, transferring glycosyl groups
FA707_09820	COG1132	(ABC) transporter
FA707_09825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FA707_09830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FA707_09835	COG0419	ATPase involved in DNA repair
FA707_09840	COG0420	3'-5' exonuclease activity
FA707_09850	COG0673	inositol 2-dehydrogenase activity
FA707_09860	COG0628	permease
FA707_09865	COG4608	Belongs to the ABC transporter superfamily
FA707_09870	COG0444	Belongs to the ABC transporter superfamily
FA707_09875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA707_09880	COG0601	transmembrane transport
FA707_09890	COG4166	transmembrane transport
FA707_09895	COG2233	PERMEase
FA707_09900	COG0402	S-adenosylhomocysteine deaminase activity
FA707_09910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FA707_09915	COG0488	(ABC) transporter
FA707_09925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FA707_09930	COG4109	DRTGG domain
FA707_09935	COG1760	l-serine dehydratase
FA707_09940	COG1760	l-serine dehydratase
FA707_09950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FA707_09955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA707_09960	COG0475	glutathione-regulated potassium exporter activity
FA707_09970	COG0204	Acyl-transferase
FA707_09975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FA707_09980	COG2827	Endonuclease containing a URI domain
FA707_09985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA707_10000	COG2731	YhcH YjgK YiaL family protein
FA707_10005	COG1653	transport
FA707_10010	COG0395	ABC-type sugar transport system, permease component
FA707_10015	COG1175	transmembrane transport
FA707_10020	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FA707_10030	COG2823	Periplasmic or secreted lipoprotein
FA707_10030	COG1652	LysM domain
FA707_10040	COG0572	uridine kinase
FA707_10045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA707_10055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FA707_10075	COG3688	RNA-binding protein containing a PIN domain
FA707_10080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA707_10085	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FA707_10090	COG0215	cysteine-tRNA ligase activity
FA707_10095	COG1045	serine acetyltransferase
FA707_10100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA707_10105	COG4956	integral membrane protein (PIN domain superfamily)
FA707_10115	COG0756	dUTP diphosphatase activity
FA707_10120	COG0384	phenazine biosynthesis protein PhzF
FA707_10135	COG1937	Protein conserved in bacteria
FA707_10140	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA707_10150	COG1187	pseudouridine synthase activity
FA707_10155	COG2244	polysaccharide biosynthetic process
FA707_10160	COG1363	Peptidase, m42
FA707_10170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA707_10175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FA707_10190	COG5002	protein histidine kinase activity
FA707_10195	COG0745	RESPONSE REGULATOR receiver
FA707_10200	COG3973	AAA domain
FA707_10205	COG1054	Belongs to the UPF0176 family
FA707_10220	COG3584	3D domain protein
FA707_10220	COG3583	domain protein
FA707_10230	COG1285	pathogenesis
FA707_10305	COG5002	protein histidine kinase activity
FA707_10315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA707_10320	COG0686	Belongs to the AlaDH PNT family
FA707_10325	COG0517	IMP dehydrogenase activity
FA707_10325	COG0516	GMP reductase activity
FA707_10340	COG0012	GTP binding
FA707_10345	COG4481	Protein conserved in bacteria
FA707_10350	COG1475	DNA binding
FA707_10355	COG1192	Involved in chromosome partitioning
FA707_10360	COG0357	Ribosomal RNA small subunit methyltransferase G
FA707_10375	COG0586	Pfam SNARE associated Golgi protein
FA707_10400	COG0445	tRNA wobble uridine modification
FA707_10405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FA707_10415	COG0706	membrane insertase activity
FA707_10420	COG0594	ribonuclease P activity
FA707_10425	COG0230	Belongs to the bacterial ribosomal protein bL34 family