locus-tag	class	description
GFK26_00025	COG0142	geranyltranstransferase activity
GFK26_00055	COG1696	Membrane protein involved in D-alanine export
GFK26_00065	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GFK26_00070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GFK26_00075	COG2755	lipolytic protein G-D-S-L family
GFK26_00075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GFK26_00095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFK26_00130	COG0831	urea catabolic process
GFK26_00140	COG0832	Belongs to the urease beta subunit family
GFK26_00145	COG0804	urea catabolic process
GFK26_00160	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GFK26_00165	COG0830	nickel cation binding
GFK26_00170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GFK26_00180	COG0583	DNA-binding transcription factor activity
GFK26_00190	COG0583	DNA-binding transcription factor activity
GFK26_00210	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_00235	COG1473	amidohydrolase
GFK26_00250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFK26_00255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GFK26_00270	COG0084	hydrolase, TatD family'
GFK26_00275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_00280	COG0714	Associated with various cellular activities
GFK26_00290	COG2304	oxidoreductase activity
GFK26_00300	COG0300	oxidoreductase activity
GFK26_00305	COG1309	transcriptional regulator
GFK26_00315	COG1024	Enoyl-CoA hydratase
GFK26_00320	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_00330	COG3396	Phenylacetate-CoA oxygenase
GFK26_00335	COG3460	Phenylacetate-CoA oxygenase
GFK26_00340	COG3396	Phenylacetate-CoA oxygenase
GFK26_00345	COG2151	metal-sulfur cluster biosynthetic enzyme
GFK26_00350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFK26_00365	COG0411	ABC transporter
GFK26_00375	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_00375	COG2030	dehydratase
GFK26_00380	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_00390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_00410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GFK26_00440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_00445	COG0583	DNA-binding transcription factor activity
GFK26_00450	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_00480	COG0601	transmembrane transport
GFK26_00500	COG0740	serine-type endopeptidase activity
GFK26_00530	COG1136	(ABC) transporter
GFK26_00535	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFK26_00545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFK26_00555	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_00570	COG3685	Protein conserved in bacteria
GFK26_00595	COG0366	Alpha amylase catalytic
GFK26_00620	COG2226	methyltransferase
GFK26_00640	COG1595	DNA-templated transcription, initiation
GFK26_00650	COG1609	Transcriptional regulator
GFK26_00655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_00660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_00670	COG1850	ribulose-bisphosphate carboxylase activity
GFK26_00685	COG2969	positive regulation of protein catabolic process
GFK26_00690	COG0625	glutathione transferase activity
GFK26_00695	COG2857	Cytochrome c1
GFK26_00700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GFK26_00705	COG0723	plastoquinol--plastocyanin reductase activity
GFK26_00725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_00735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFK26_00740	COG0489	protein tyrosine kinase activity
GFK26_00740	COG3206	protein involved in exopolysaccharide biosynthesis
GFK26_00755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFK26_00810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GFK26_00815	COG1596	polysaccharide export
GFK26_00820	COG1970	mechanosensitive ion channel activity
GFK26_00825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GFK26_00830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFK26_00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_00845	COG0805	protein transport
GFK26_00850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFK26_00855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GFK26_00860	COG0537	adenosine 5'-monophosphoramidase activity
GFK26_00870	COG0140	phosphoribosyl-ATP diphosphatase activity
GFK26_00875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GFK26_00880	COG0107	imidazoleglycerol-phosphate synthase activity
GFK26_00890	COG1301	dicarboxylic acid transport
GFK26_00895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_00900	COG0583	DNA-binding transcription factor activity
GFK26_00905	COG2814	Major facilitator Superfamily
GFK26_00910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GFK26_00920	COG0131	Imidazoleglycerol-phosphate dehydratase
GFK26_00925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFK26_00945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GFK26_00950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFK26_00955	COG5007	Belongs to the BolA IbaG family
GFK26_00960	COG0842	Transport permease protein
GFK26_00965	COG1131	(ABC) transporter
GFK26_00980	COG2853	Lipoprotein
GFK26_00985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFK26_00990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFK26_00995	COG1127	ABC transporter
GFK26_01005	COG0070	glutamate synthase
GFK26_01005	COG0067	glutamate synthase
GFK26_01005	COG0069	glutamate synthase activity
GFK26_01030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GFK26_01035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GFK26_01040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFK26_01075	COG1965	Belongs to the frataxin family
GFK26_01080	COG0019	diaminopimelate decarboxylase activity
GFK26_01085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GFK26_01090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_01095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_01100	COG1333	cytochrome c biogenesis protein
GFK26_01110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GFK26_01120	COG1560	Kdo2-lipid A biosynthetic process
GFK26_01130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GFK26_01135	COG4772	TonB-dependent receptor
GFK26_01150	COG4774	siderophore transport
GFK26_01155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_01165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GFK26_01170	COG0459	protein refolding
GFK26_01175	COG1070	Carbohydrate kinase
GFK26_01180	COG4753	response regulator
GFK26_01180	COG2207	Transcriptional regulator
GFK26_01190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFK26_01200	COG0246	Mannitol dehydrogenase
GFK26_01205	COG3842	ATPase activity
GFK26_01210	COG0395	ABC-type sugar transport system, permease component
GFK26_01215	COG1175	transmembrane transport
GFK26_01245	COG0166	Belongs to the GPI family
GFK26_01250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFK26_01265	COG3842	ATPase activity
GFK26_01275	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_01280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GFK26_01285	COG3384	dioxygenase
GFK26_01290	COG4608	Belongs to the ABC transporter superfamily
GFK26_01295	COG0444	Belongs to the ABC transporter superfamily
GFK26_01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_01325	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GFK26_01330	COG1765	OsmC-like protein
GFK26_01345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_01430	COG0583	DNA-binding transcription factor activity
GFK26_01435	COG2233	PERMEase
GFK26_01445	COG2010	Cytochrome c
GFK26_01450	COG2863	cytochrome
GFK26_01460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_01465	COG2271	Major facilitator Superfamily
GFK26_01480	COG3842	ATPase activity
GFK26_01485	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_01490	COG4178	(ABC) transporter
GFK26_01495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GFK26_01505	COG1132	(ABC) transporter
GFK26_01545	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_01550	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_01560	COG1129	ABC transporter
GFK26_01565	COG4214	carbohydrate transport
GFK26_01575	COG4213	ABC transporter substrate-binding protein
GFK26_01580	COG1879	ABC-type sugar transport system periplasmic component
GFK26_01585	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_01595	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_01600	COG3386	PFAM SMP-30 Gluconolaconase
GFK26_01615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_01620	COG0583	DNA-binding transcription factor activity
GFK26_01625	COG0697	spore germination
GFK26_01640	COG0506	proline dehydrogenase activity
GFK26_01640	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFK26_01640	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFK26_01650	COG5295	Hep Hag repeat protein
GFK26_01660	COG2832	Protein of unknown function (DUF454)
GFK26_01675	COG0235	Class ii aldolase
GFK26_01680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_01685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_01690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_01700	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_01710	COG0583	DNA-binding transcription factor activity
GFK26_01725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GFK26_01735	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GFK26_01740	COG3387	PFAM Glycoside hydrolase 15-related
GFK26_01750	COG0617	tRNA 3'-terminal CCA addition
GFK26_01765	COG1285	pathogenesis
GFK26_01770	COG0741	lytic transglycosylase activity
GFK26_01770	COG0739	heme binding
GFK26_01770	COG1196	nuclear chromosome segregation
GFK26_01775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFK26_01780	COG0583	DNA-binding transcription factor activity
GFK26_01795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_01805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_01815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_01835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_01840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_01850	COG2175	clavaminate synthase activity
GFK26_01865	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_01875	COG0037	tRNA processing
GFK26_01910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFK26_01915	COG2205	protein histidine kinase activity
GFK26_01925	COG2204	response regulator
GFK26_01935	COG3416	Protein conserved in bacteria
GFK26_01935	COG2943	transferase activity, transferring hexosyl groups
GFK26_01950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFK26_01955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_01985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFK26_02005	COG2264	protein methyltransferase activity
GFK26_02010	COG0439	Biotin carboxylase
GFK26_02015	COG0511	ligase activity, forming carbon-carbon bonds
GFK26_02020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_02030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFK26_02040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFK26_02050	COG0312	modulator of DNA gyrase
GFK26_02055	COG0772	Belongs to the SEDS family
GFK26_02065	COG2197	response regulator
GFK26_02070	COG3150	esterase
GFK26_02085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_02090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_02105	COG0575	Belongs to the CDS family
GFK26_02115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GFK26_02120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFK26_02125	COG0583	DNA-binding transcription factor activity
GFK26_02130	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GFK26_02145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GFK26_02150	COG1181	Belongs to the D-alanine--D-alanine ligase family
GFK26_02155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFK26_02160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFK26_02165	COG0772	Belongs to the SEDS family
GFK26_02170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GFK26_02175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFK26_02180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_02185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFK26_02200	COG0275	rRNA processing
GFK26_02205	COG2001	Belongs to the MraZ family
GFK26_02210	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GFK26_02215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GFK26_02225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GFK26_02235	COG0523	cobalamin synthesis protein
GFK26_02240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GFK26_02245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GFK26_02260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GFK26_02280	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GFK26_02290	COG1335	isochorismatase
GFK26_02295	COG0583	DNA-binding transcription factor activity
GFK26_02325	COG2207	Transcriptional regulator
GFK26_02325	COG0662	Cupin 2, conserved barrel domain protein
GFK26_02355	COG0656	L-ascorbic acid biosynthetic process
GFK26_02375	COG2807	transmembrane transport
GFK26_02395	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_02400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_02405	COG1187	pseudouridine synthase activity
GFK26_02420	COG1566	PFAM secretion protein HlyD family protein
GFK26_02435	COG1846	Transcriptional regulator
GFK26_02445	COG3604	Transcriptional regulator
GFK26_02460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GFK26_02475	COG0501	Belongs to the peptidase M48B family
GFK26_02495	COG0418	dihydroorotase activity
GFK26_02500	COG1595	DNA-templated transcription, initiation
GFK26_02520	COG0747	negative chemotaxis
GFK26_02530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_02535	COG4608	Belongs to the ABC transporter superfamily
GFK26_02540	COG0444	Belongs to the ABC transporter superfamily
GFK26_02545	COG0154	amidase activity
GFK26_02555	COG1573	uracil-dna glycosylase
GFK26_02565	COG0583	DNA-binding transcription factor activity
GFK26_02570	COG1024	Enoyl-CoA hydratase
GFK26_02570	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_02575	COG0183	Belongs to the thiolase family
GFK26_02580	COG1960	acyl-CoA dehydrogenase activity
GFK26_02585	COG1960	acyl-CoA dehydrogenase activity
GFK26_02590	COG1024	Enoyl-CoA hydratase
GFK26_02595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_02605	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_02650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_02655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFK26_02670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_02675	COG1957	nucleoside hydrolase
GFK26_02685	COG1126	abc transporter atp-binding protein
GFK26_02690	COG0765	amino acid transport
GFK26_02695	COG0765	amino acid transport
GFK26_02700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_02705	COG0583	DNA-binding transcription factor activity
GFK26_02710	COG0154	amidase activity
GFK26_02715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFK26_02720	COG5265	(ABC) transporter
GFK26_02725	COG1607	acyl-coa hydrolase
GFK26_02730	COG0683	leucine binding
GFK26_02735	COG1024	Enoyl-CoA hydratase
GFK26_02755	COG0183	Belongs to the thiolase family
GFK26_02760	COG2852	Protein conserved in bacteria
GFK26_02765	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_02765	COG1024	Enoyl-CoA hydratase
GFK26_02775	COG1960	acyl-CoA dehydrogenase activity
GFK26_02785	COG4221	oxidoreductase activity
GFK26_02790	COG0583	DNA-binding transcription factor activity
GFK26_02800	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_02805	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_02810	COG2186	Transcriptional regulator
GFK26_02815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_02825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_02830	COG2721	sulfolactate sulfo-lyase activity
GFK26_02835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GFK26_02845	COG1309	transcriptional regulator
GFK26_02850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GFK26_02865	COG1215	transferase activity, transferring glycosyl groups
GFK26_02870	COG1216	Glycosyl transferase, family 2
GFK26_02870	COG0438	transferase activity, transferring glycosyl groups
GFK26_02900	COG1215	transferase activity, transferring glycosyl groups
GFK26_02910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFK26_02920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFK26_02945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_02970	COG0697	spore germination
GFK26_02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_02995	COG0384	phenazine biosynthesis protein PhzF
GFK26_03000	COG0625	glutathione transferase activity
GFK26_03005	COG0384	phenazine biosynthesis protein PhzF
GFK26_03020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_03035	COG0726	polysaccharide deacetylase
GFK26_03035	COG1649	PFAM Uncharacterised BCR, COG1649
GFK26_03040	COG1215	transferase activity, transferring glycosyl groups
GFK26_03050	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_03055	COG0583	DNA-binding transcription factor activity
GFK26_03095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFK26_03100	COG4232	protein-disulfide reductase activity
GFK26_03105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_03120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GFK26_03125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFK26_03145	COG0679	Auxin Efflux Carrier
GFK26_03150	COG0210	DNA helicase
GFK26_03165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GFK26_03195	COG3121	Chaperone
GFK26_03200	COG3188	usher protein
GFK26_03245	COG0582	viral genome integration into host DNA
GFK26_03275	COG4983	Phage plasmid primase, P4 family domain protein
GFK26_03290	COG0484	heat shock protein binding
GFK26_03415	COG4974	Belongs to the 'phage' integrase family
GFK26_03420	COG0582	viral genome integration into host DNA
GFK26_03425	COG4974	Belongs to the 'phage' integrase family
GFK26_03455	COG0583	DNA-binding transcription factor activity
GFK26_03545	COG0789	Transcriptional regulator
GFK26_03570	COG1785	Belongs to the alkaline phosphatase family
GFK26_03575	COG1785	Belongs to the alkaline phosphatase family
GFK26_03640	COG1929	Belongs to the glycerate kinase type-1 family
GFK26_03645	COG4232	protein-disulfide reductase activity
GFK26_03675	COG2433	Pfam Transposase IS66
GFK26_03695	COG0785	Cytochrome C biogenesis protein
GFK26_03700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_03710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_03715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFK26_03720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFK26_03725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_03745	COG0789	Transcriptional regulator
GFK26_03760	COG0672	)-iron permease
GFK26_03790	COG0723	plastoquinol--plastocyanin reductase activity
GFK26_03800	COG0347	Belongs to the P(II) protein family
GFK26_03820	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_03850	COG2132	Multicopper oxidase
GFK26_03865	COG3387	PFAM Glycoside hydrolase 15-related
GFK26_03975	COG0583	DNA-binding transcription factor activity
GFK26_03990	COG2204	response regulator
GFK26_03995	COG5000	phosphorelay sensor kinase activity
GFK26_04005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFK26_04005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_04015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFK26_04020	COG0085	RNA polymerase activity
GFK26_04025	COG0222	ribosome binding
GFK26_04030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GFK26_04035	COG0081	regulation of translation
GFK26_04040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GFK26_04050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFK26_04060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFK26_04080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GFK26_04085	COG0134	indole-3-glycerol-phosphate synthase activity
GFK26_04090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFK26_04120	COG0546	phosphoglycolate phosphatase activity
GFK26_04125	COG0583	DNA-binding transcription factor activity
GFK26_04130	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_04150	COG1538	Outer membrane efflux protein
GFK26_04345	COG3501	Rhs element vgr protein
GFK26_04355	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_04360	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_04375	COG5002	protein histidine kinase activity
GFK26_04395	COG3210	domain, Protein
GFK26_04410	COG3501	Rhs element vgr protein
GFK26_04440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFK26_04445	COG2967	ApaG domain
GFK26_04460	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GFK26_04465	COG4977	sequence-specific DNA binding
GFK26_04470	COG1335	isochorismatase
GFK26_04495	COG0583	DNA-binding transcription factor activity
GFK26_04500	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_04530	COG2197	response regulator
GFK26_04555	COG0069	glutamate synthase activity
GFK26_04595	COG2353	YceI-like domain
GFK26_04605	COG1280	lysine exporter protein (LysE YggA)
GFK26_04610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_04620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_04625	COG1137	ATPase activity
GFK26_04630	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GFK26_04635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFK26_04645	COG0018	arginyl-trna synthetase
GFK26_04665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_04670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_04675	COG1414	Transcriptional regulator
GFK26_04690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GFK26_04710	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GFK26_04715	COG0583	DNA-binding transcription factor activity
GFK26_04730	COG0205	6-phosphofructokinase activity
GFK26_04745	COG2814	Major facilitator Superfamily
GFK26_04760	COG0154	amidase activity
GFK26_04765	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_04780	COG0121	glutamine amidotransferase
GFK26_04795	COG0189	ligase activity
GFK26_04800	COG3135	benzoate transporter
GFK26_04805	COG3158	transport of potassium into the cell
GFK26_04815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GFK26_04830	COG0495	leucyl-tRNA aminoacylation
GFK26_04835	COG2072	flavoprotein involved in K transport
GFK26_04840	COG0366	Alpha amylase catalytic
GFK26_04865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GFK26_04870	COG0297	glycogen (starch) synthase activity
GFK26_04875	COG0058	SHG alpha-glucan phosphorylase activity
GFK26_04895	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_04900	COG0735	belongs to the Fur family
GFK26_04905	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GFK26_04915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFK26_04935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFK26_04940	COG0747	negative chemotaxis
GFK26_04945	COG4608	Belongs to the ABC transporter superfamily
GFK26_04950	COG0444	Belongs to the ABC transporter superfamily
GFK26_04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_04960	COG0601	transmembrane transport
GFK26_04965	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_04970	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GFK26_04975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GFK26_04980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GFK26_04985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GFK26_05000	COG0482	sulfurtransferase activity
GFK26_05005	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_05010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_05045	COG0629	single-stranded DNA binding
GFK26_05090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFK26_05095	COG1070	Carbohydrate kinase
GFK26_05110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_05115	COG0667	Aldo Keto reductase
GFK26_05140	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_05150	COG0411	ABC transporter
GFK26_05155	COG1129	ABC transporter
GFK26_05160	COG0659	secondary active sulfate transmembrane transporter activity
GFK26_05180	COG1946	Acyl-CoA thioesterase
GFK26_05190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_05195	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_05205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_05220	COG0583	DNA-binding transcription factor activity
GFK26_05250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_05260	COG1879	ABC-type sugar transport system periplasmic component
GFK26_05270	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_05275	COG1063	alcohol dehydrogenase
GFK26_05280	COG1070	Carbohydrate kinase
GFK26_05285	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_05300	COG0243	molybdopterin cofactor binding
GFK26_05315	COG1473	amidohydrolase
GFK26_05320	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_05330	COG2733	membrane
GFK26_05345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_05350	COG0439	Biotin carboxylase
GFK26_05360	COG1960	acyl-CoA dehydrogenase activity
GFK26_05365	COG1960	acyl-CoA dehydrogenase activity
GFK26_05370	COG0513	Belongs to the DEAD box helicase family
GFK26_05375	COG0023	Translation Initiation Factor
GFK26_05385	COG0724	RNA recognition motif
GFK26_05405	COG0004	ammonium transporteR
GFK26_05415	COG0028	Belongs to the TPP enzyme family
GFK26_05435	COG2827	Endonuclease containing a URI domain
GFK26_05450	COG0583	DNA-binding transcription factor activity
GFK26_05455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFK26_05460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFK26_05485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFK26_05500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_05510	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GFK26_05520	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_05525	COG0768	penicillin binding
GFK26_05535	COG1792	Involved in formation and maintenance of cell shape
GFK26_05540	COG1077	Cell shape determining protein MreB Mrl
GFK26_05545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFK26_05550	COG0154	amidase activity
GFK26_05555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFK26_05565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFK26_05570	COG0708	Exodeoxyribonuclease III
GFK26_05590	COG0501	Belongs to the peptidase M48B family
GFK26_05595	COG2211	Major facilitator Superfamily
GFK26_05610	COG0579	oxidoreductase
GFK26_05615	COG0745	RESPONSE REGULATOR receiver
GFK26_05620	COG2205	protein histidine kinase activity
GFK26_05645	COG2974	May be involved in recombination
GFK26_05660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFK26_05670	COG1846	Transcriptional regulator
GFK26_05690	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_05695	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_05715	COG3971	2-oxopent-4-enoate hydratase activity
GFK26_05725	COG0129	dihydroxy-acid dehydratase activity
GFK26_05740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_05750	COG0217	transcriptional regulatory protein
GFK26_05760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFK26_05775	COG0386	Belongs to the glutathione peroxidase family
GFK26_05785	COG0247	lactate metabolic process
GFK26_05790	COG0277	FAD linked oxidase domain protein
GFK26_05795	COG0277	FAD linked oxidase domain protein
GFK26_05800	COG1620	l-lactate permease
GFK26_05805	COG0583	DNA-binding transcription factor activity
GFK26_05815	COG0004	ammonium transporteR
GFK26_05820	COG0347	Belongs to the P(II) protein family
GFK26_05910	COG3501	Rhs element vgr protein
GFK26_05915	COG3501	Rhs element vgr protein
GFK26_05920	COG3501	Rhs element vgr protein
GFK26_05980	COG2080	2 iron, 2 sulfur cluster binding
GFK26_05985	COG1335	isochorismatase
GFK26_06005	COG0683	leucine binding
GFK26_06035	COG1309	transcriptional regulator
GFK26_06060	COG1410	methionine synthase
GFK26_06060	COG0646	methionine synthase
GFK26_06065	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GFK26_06070	COG5380	lipid catabolic process
GFK26_06105	COG1228	amidohydrolase
GFK26_06135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GFK26_06140	COG2986	histidine ammonia-lyase
GFK26_06150	COG1116	anion transmembrane transporter activity
GFK26_06155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_06185	COG1070	Carbohydrate kinase
GFK26_06200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_06205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFK26_06210	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GFK26_06275	COG0633	Ferredoxin
GFK26_06280	COG0683	leucine binding
GFK26_06300	COG0410	ABC transporter
GFK26_06315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_06320	COG0700	Nucleoside recognition
GFK26_06325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GFK26_06335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_06350	COG2066	Belongs to the glutaminase family
GFK26_06380	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_06385	COG1129	ABC transporter
GFK26_06395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_06405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_06430	COG0583	DNA-binding transcription factor activity
GFK26_06445	COG1573	uracil-dna glycosylase
GFK26_06455	COG1760	l-serine dehydratase
GFK26_06460	COG1473	amidohydrolase
GFK26_06470	COG0583	DNA-binding transcription factor activity
GFK26_06485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_06490	COG1960	acyl-CoA dehydrogenase activity
GFK26_06495	COG0583	DNA-binding transcription factor activity
GFK26_06510	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_06520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_06535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_06535	COG1116	anion transmembrane transporter activity
GFK26_06540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_06545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_06550	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_06570	COG1959	2 iron, 2 sulfur cluster binding
GFK26_06600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GFK26_06655	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_06660	COG1942	4-Oxalocrotonate Tautomerase
GFK26_06665	COG3284	Transcriptional regulator
GFK26_06670	COG1819	glycosyl
GFK26_06675	COG1309	transcriptional regulator
GFK26_06695	COG3246	L-lysine catabolic process to acetate
GFK26_06705	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_06720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_06745	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_06750	COG2233	PERMEase
GFK26_06760	COG2894	cell division
GFK26_06765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GFK26_06785	COG0583	DNA-binding transcription factor activity
GFK26_06800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GFK26_06820	COG0411	ABC transporter
GFK26_06865	COG2096	Adenosyltransferase
GFK26_06875	COG0277	FAD linked oxidase domain protein
GFK26_06895	COG1192	Involved in chromosome partitioning
GFK26_06905	COG0357	Ribosomal RNA small subunit methyltransferase G
GFK26_06910	COG0445	tRNA wobble uridine modification
GFK26_06920	COG5487	UPF0391 membrane protein
GFK26_06930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_06935	COG1024	Enoyl-CoA hydratase
GFK26_06940	COG1024	Enoyl-CoA hydratase
GFK26_06950	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_06960	COG1902	pentaerythritol trinitrate reductase activity
GFK26_06965	COG3501	Rhs element vgr protein
GFK26_06995	COG0456	acetyltransferase
GFK26_07000	COG0642	Histidine kinase
GFK26_07005	COG0745	RESPONSE REGULATOR receiver
GFK26_07015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_07030	COG2217	Heavy metal translocating P-type atpase
GFK26_07035	COG2608	mercury ion transmembrane transporter activity
GFK26_07050	COG0745	RESPONSE REGULATOR receiver
GFK26_07055	COG2205	protein histidine kinase activity
GFK26_07070	COG1472	Belongs to the glycosyl hydrolase 3 family
GFK26_07095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_07100	COG0456	acetyltransferase
GFK26_07100	COG0454	-acetyltransferase
GFK26_07125	COG3568	Endonuclease Exonuclease Phosphatase
GFK26_07130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_07135	COG0392	lysyltransferase activity
GFK26_07145	COG1408	metallophosphoesterase
GFK26_07175	COG0187	DNA topoisomerase II activity
GFK26_07180	COG0592	DNA-directed DNA polymerase activity
GFK26_07185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFK26_07190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GFK26_07195	COG0594	ribonuclease P activity
GFK26_07200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GFK26_07205	COG0706	membrane insertase activity
GFK26_07210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GFK26_07215	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GFK26_07215	COG2066	Belongs to the glutaminase family
GFK26_07235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GFK26_07245	COG0300	oxidoreductase activity
GFK26_07255	COG2119	membrane
GFK26_07260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_07265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_07265	COG2813	Specifically methylates the guanine in position
GFK26_07270	COG1739	Uncharacterized protein family UPF0029
GFK26_07275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_07295	COG2267	carboxylic ester hydrolase activity
GFK26_07300	COG2814	Major facilitator Superfamily
GFK26_07315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFK26_07325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GFK26_07330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_07335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GFK26_07350	COG0280	phosphate acetyltransferase
GFK26_07350	COG0281	malic enzyme
GFK26_07370	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GFK26_07415	COG0006	proline dipeptidase activity
GFK26_07425	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GFK26_07430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFK26_07435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFK26_07470	COG3025	triphosphatase activity
GFK26_07480	COG1047	Peptidyl-prolyl cis-trans
GFK26_07500	COG1741	Belongs to the pirin family
GFK26_07505	COG1473	amidohydrolase
GFK26_07520	COG3938	Belongs to the proline racemase family
GFK26_07525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_07540	COG1802	Transcriptional regulator
GFK26_07550	COG0697	spore germination
GFK26_07560	COG0513	Belongs to the DEAD box helicase family
GFK26_07565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GFK26_07580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFK26_07585	COG1960	acyl-CoA dehydrogenase activity
GFK26_07605	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_07610	COG0583	DNA-binding transcription factor activity
GFK26_07630	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GFK26_07630	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GFK26_07645	COG0642	Histidine kinase
GFK26_07665	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFK26_07670	COG2137	regulation of response to DNA damage stimulus
GFK26_07680	COG4682	membrane
GFK26_07690	COG3781	membrane
GFK26_07695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GFK26_07700	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_07705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GFK26_07710	COG0861	Integral membrane protein TerC family
GFK26_07715	COG0631	protein serine/threonine phosphatase activity
GFK26_07720	COG1716	ATPase activity
GFK26_07735	COG4969	Belongs to the N-Me-Phe pilin family
GFK26_07740	COG3307	-O-antigen
GFK26_07790	COG0315	cyclic pyranopterin monophosphate synthase activity
GFK26_07795	COG4783	chaperone-mediated protein folding
GFK26_07800	COG1950	PFAM Membrane protein of
GFK26_07810	COG0861	Integral membrane protein TerC family
GFK26_07825	COG4681	YaeQ
GFK26_07835	COG0625	glutathione transferase activity
GFK26_07850	COG1595	DNA-templated transcription, initiation
GFK26_07855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GFK26_07865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GFK26_07875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_07885	COG4566	intracellular signal transduction
GFK26_07910	COG1522	sequence-specific DNA binding
GFK26_07920	COG2186	Transcriptional regulator
GFK26_07925	COG2271	Major facilitator Superfamily
GFK26_07930	COG2084	Dehydrogenase
GFK26_07935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_07940	COG3395	kinase activity
GFK26_07945	COG0235	Class ii aldolase
GFK26_07950	COG3622	Belongs to the hyi family
GFK26_07960	COG0251	oxidation-reduction process
GFK26_07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_08005	COG2814	Major facilitator Superfamily
GFK26_08010	COG0765	amino acid transport
GFK26_08025	COG1522	sequence-specific DNA binding
GFK26_08040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFK26_08045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFK26_08055	COG2922	Belongs to the Smg family
GFK26_08060	COG0758	DNA mediated transformation
GFK26_08070	COG0242	peptide deformylase activity
GFK26_08080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFK26_08110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_08130	COG0126	phosphoglycerate kinase activity
GFK26_08135	COG0469	pyruvate kinase activity
GFK26_08140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GFK26_08145	COG1522	sequence-specific DNA binding
GFK26_08160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GFK26_08170	COG3550	peptidyl-serine autophosphorylation
GFK26_08175	COG3620	sequence-specific DNA binding
GFK26_08185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFK26_08190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFK26_08195	COG0009	L-threonylcarbamoyladenylate synthase
GFK26_08205	COG2027	D-alanyl-D-alanine carboxypeptidase
GFK26_08210	COG0494	nUDIX hydrolase
GFK26_08215	COG1349	DNA-binding transcription factor activity
GFK26_08225	COG1214	PFAM Peptidase M22, glycoprotease
GFK26_08240	COG0284	orotidine-5'-phosphate decarboxylase activity
GFK26_08285	COG0343	queuine tRNA-ribosyltransferase activity
GFK26_08290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GFK26_08300	COG1090	epimerase
GFK26_08305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFK26_08310	COG1280	lysine exporter protein (LysE YggA)
GFK26_08330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFK26_08335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_08340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_08345	COG4770	biotin carboxylase activity
GFK26_08515	COG3501	Rhs element vgr protein
GFK26_08565	COG0783	Belongs to the Dps family
GFK26_08570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GFK26_08590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GFK26_08595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GFK26_08600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GFK26_08605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFK26_08610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GFK26_08615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GFK26_08620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GFK26_08625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GFK26_08630	COG1841	ribosomal large subunit assembly
GFK26_08635	COG0200	Binds to the 23S rRNA
GFK26_08640	COG0201	protein transport
GFK26_08645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFK26_08650	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GFK26_08655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GFK26_08660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GFK26_08665	COG0202	RNA polymerase activity
GFK26_08670	COG0203	ribosomal protein L17
GFK26_08690	COG1960	acyl-CoA dehydrogenase activity
GFK26_08695	COG1024	Enoyl-CoA hydratase
GFK26_08710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_08725	COG0583	DNA-binding transcription factor activity
GFK26_08730	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_08740	COG0022	dehydrogenase e1 component
GFK26_08745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFK26_08755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_08880	COG4213	ABC transporter substrate-binding protein
GFK26_08885	COG4214	carbohydrate transport
GFK26_08890	COG1129	ABC transporter
GFK26_08895	COG1940	carbohydrate kinase activity
GFK26_08900	COG4993	Dehydrogenase
GFK26_08950	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_08975	COG0411	ABC transporter
GFK26_08980	COG1022	Amp-dependent synthetase and ligase
GFK26_08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_08995	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_09025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GFK26_09040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_09070	COG4654	Cytochrome c, class I
GFK26_09075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_09110	COG2391	methyltransferase activity
GFK26_09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_09140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GFK26_09145	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GFK26_09150	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GFK26_09160	COG2205	protein histidine kinase activity
GFK26_09165	COG0745	RESPONSE REGULATOR receiver
GFK26_09185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFK26_09190	COG1187	pseudouridine synthase activity
GFK26_09200	COG0745	RESPONSE REGULATOR receiver
GFK26_09205	COG0642	Histidine kinase
GFK26_09215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFK26_09225	COG0583	DNA-binding transcription factor activity
GFK26_09230	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_09235	COG0326	Molecular chaperone. Has ATPase activity
GFK26_09255	COG0714	Associated with various cellular activities
GFK26_09265	COG3552	Protein containing von Willebrand factor type A (VWA) domain
GFK26_09270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_09280	COG1960	acyl-CoA dehydrogenase activity
GFK26_09285	COG0583	DNA-binding transcription factor activity
GFK26_09290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFK26_09300	COG1764	response to oxidative stress
GFK26_09305	COG1846	Transcriptional regulator
GFK26_09315	COG0842	Transport permease protein
GFK26_09320	COG1131	(ABC) transporter
GFK26_09330	COG0625	glutathione transferase activity
GFK26_09345	COG0640	Transcriptional regulator
GFK26_09360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFK26_09365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_09375	COG0574	Belongs to the PEP-utilizing enzyme family
GFK26_09375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFK26_09385	COG0640	Transcriptional regulator
GFK26_09410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GFK26_09425	COG2207	Transcriptional regulator
GFK26_09430	COG1652	LysM domain
GFK26_09435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GFK26_09450	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_09455	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GFK26_09470	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_09480	COG0411	ABC transporter
GFK26_09495	COG1022	Amp-dependent synthetase and ligase
GFK26_09510	COG2095	MarC family integral membrane protein
GFK26_09515	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_09525	COG0412	Dienelactone hydrolase
GFK26_09530	COG0583	DNA-binding transcription factor activity
GFK26_09540	COG0598	Magnesium transport protein CorA
GFK26_09565	COG2945	thiolester hydrolase activity
GFK26_09570	COG1686	Belongs to the peptidase S11 family
GFK26_09575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GFK26_09580	COG0049	tRNA binding
GFK26_09585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_09590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFK26_09595	COG0051	transcription antitermination factor activity, RNA binding
GFK26_09610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GFK26_09615	COG0088	Forms part of the polypeptide exit tunnel
GFK26_09620	COG0089	rRNA binding
GFK26_09625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GFK26_09630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GFK26_09635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GFK26_09640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GFK26_09645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GFK26_09650	COG0255	Belongs to the universal ribosomal protein uL29 family
GFK26_09655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GFK26_09660	COG0678	peroxiredoxin activity
GFK26_09675	COG3909	cytochrome
GFK26_09680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_09695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFK26_09700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFK26_09725	COG2205	protein histidine kinase activity
GFK26_09730	COG2130	NADP-dependent
GFK26_09750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFK26_09755	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_09770	COG2271	Major facilitator Superfamily
GFK26_09780	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_09785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GFK26_09790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GFK26_09795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GFK26_09800	COG0142	geranyltranstransferase activity
GFK26_09810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_09830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_09840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFK26_09845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFK26_09850	COG0321	lipoyl(octanoyl) transferase activity
GFK26_09855	COG2921	Belongs to the UPF0250 family
GFK26_09870	COG0356	it plays a direct role in the translocation of protons across the membrane
GFK26_09880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GFK26_09885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFK26_09890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GFK26_09895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GFK26_09900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GFK26_09905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GFK26_09920	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_09925	COG1879	ABC-type sugar transport system periplasmic component
GFK26_09945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GFK26_09945	COG1793	dna ligase
GFK26_09950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GFK26_09950	COG1793	dna ligase
GFK26_09955	COG1201	RNA secondary structure unwinding
GFK26_09960	COG3118	belongs to the thioredoxin family
GFK26_10010	COG1538	Outer membrane efflux protein
GFK26_10020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_10045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFK26_10050	COG0792	nuclease activity
GFK26_10055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GFK26_10065	COG2084	Dehydrogenase
GFK26_10095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFK26_10110	COG1505	serine-type exopeptidase activity
GFK26_10130	COG1309	transcriptional regulator
GFK26_10140	COG2124	cytochrome p450
GFK26_10140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFK26_10155	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_10160	COG0439	Biotin carboxylase
GFK26_10220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_10265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_10305	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_10310	COG3186	Phenylalanine-4-hydroxylase
GFK26_10325	COG1522	sequence-specific DNA binding
GFK26_10340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GFK26_10355	COG0671	phosphoesterase, PA-phosphatase related
GFK26_10365	COG1597	lipid kinase activity
GFK26_10370	COG0752	glycyl-tRNA synthetase alpha subunit
GFK26_10375	COG0751	glycine-tRNA ligase activity
GFK26_10380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFK26_10405	COG0564	pseudouridine synthase activity
GFK26_10420	COG0789	Transcriptional regulator
GFK26_10425	COG0288	reversible hydration of carbon dioxide
GFK26_10430	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GFK26_10435	COG0183	Belongs to the thiolase family
GFK26_10445	COG1960	acyl-CoA dehydrogenase activity
GFK26_10450	COG1408	metallophosphoesterase
GFK26_10470	COG3012	SEC-C Motif Domain Protein
GFK26_10475	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GFK26_10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_10505	COG1960	acyl-CoA dehydrogenase activity
GFK26_10510	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_10515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_10520	COG1024	Enoyl-CoA hydratase
GFK26_10545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_10550	COG1414	Transcriptional regulator
GFK26_10565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_10575	COG1254	Belongs to the acylphosphatase family
GFK26_10590	COG2815	serine threonine protein kinase
GFK26_10590	COG0515	serine threonine protein kinase
GFK26_10595	COG2116	formate transmembrane transporter activity
GFK26_10600	COG2146	nitrite reductase [NAD(P)H] activity
GFK26_10605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFK26_10625	COG0477	Major facilitator Superfamily
GFK26_10635	COG0683	leucine binding
GFK26_10640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFK26_10645	COG2423	ornithine cyclodeaminase activity
GFK26_10670	COG4555	ABC transporter
GFK26_10685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GFK26_10695	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFK26_10715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GFK26_10730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GFK26_10735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GFK26_10750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GFK26_10755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GFK26_10760	COG0316	Belongs to the HesB IscA family
GFK26_10765	COG2814	Major facilitator Superfamily
GFK26_10770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GFK26_10795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFK26_10800	COG1490	D-aminoacyl-tRNA deacylase activity
GFK26_10810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GFK26_10815	COG1702	phosphate starvation-inducible protein PhoH
GFK26_10820	COG0632	four-way junction helicase activity
GFK26_10835	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_10900	COG4589	Belongs to the CDS family
GFK26_10915	COG2453	phosphatase
GFK26_10915	COG0671	phosphoesterase, PA-phosphatase related
GFK26_10920	COG2267	carboxylic ester hydrolase activity
GFK26_10925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFK26_10950	COG1960	acyl-CoA dehydrogenase activity
GFK26_10955	COG1960	acyl-CoA dehydrogenase activity
GFK26_10965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_10970	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_10975	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_10990	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_10995	COG2909	trisaccharide binding
GFK26_11000	COG0183	Belongs to the thiolase family
GFK26_11005	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_11005	COG1024	Enoyl-CoA hydratase
GFK26_11025	COG1024	Enoyl-CoA hydratase
GFK26_11035	COG0183	Belongs to the thiolase family
GFK26_11045	COG0410	ABC transporter
GFK26_11050	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_11060	COG1024	Enoyl-CoA hydratase
GFK26_11195	COG0457	Tetratricopeptide repeat
GFK26_11250	COG0778	Nitroreductase
GFK26_11275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GFK26_11275	COG2885	chlorophyll binding
GFK26_11315	COG1024	Enoyl-CoA hydratase
GFK26_11330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFK26_11335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_11345	COG1869	D-ribose catabolic process
GFK26_11350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_11355	COG1609	Transcriptional regulator
GFK26_11360	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_11365	COG1129	ABC transporter
GFK26_11370	COG1879	ABC-type sugar transport system periplasmic component
GFK26_11375	COG0012	GTP binding
GFK26_11390	COG1238	metal cluster binding
GFK26_11400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GFK26_11405	COG0138	bifunctional purine biosynthesis protein purh
GFK26_11415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GFK26_11425	COG1773	rubredoxin
GFK26_11445	COG0840	transmembrane signaling receptor activity
GFK26_11455	COG0415	Belongs to the DNA photolyase family
GFK26_11460	COG1678	Uncharacterized ACR, COG1678
GFK26_11465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFK26_11470	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFK26_11475	COG0540	Belongs to the ATCase OTCase family
GFK26_11480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFK26_11500	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_11520	COG0410	ABC transporter
GFK26_11530	COG0697	spore germination
GFK26_11535	COG1902	pentaerythritol trinitrate reductase activity
GFK26_11570	COG2205	protein histidine kinase activity
GFK26_11575	COG0745	RESPONSE REGULATOR receiver
GFK26_11580	COG0745	RESPONSE REGULATOR receiver
GFK26_11615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_11625	COG3485	protocatechuate 3,4-dioxygenase
GFK26_11630	COG3485	protocatechuate 3,4-dioxygenase
GFK26_11635	COG0583	DNA-binding transcription factor activity
GFK26_11650	COG2885	chlorophyll binding
GFK26_11655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFK26_11665	COG2274	protein secretion by the type I secretion system
GFK26_11670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_11730	COG4964	Belongs to the GSP D family
GFK26_11755	COG3063	Type IV pilus biogenesis stability protein PilW
GFK26_11765	COG1414	Transcriptional regulator
GFK26_11775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFK26_11780	COG0183	Belongs to the thiolase family
GFK26_11785	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_11790	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_11805	COG0693	protein deglycase activity
GFK26_11810	COG0395	ABC-type sugar transport system, permease component
GFK26_11825	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_11835	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_11845	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_11870	COG0601	transmembrane transport
GFK26_11890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_11895	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_11900	COG2003	Belongs to the UPF0758 family
GFK26_11910	COG4771	TonB-dependent receptor
GFK26_11930	COG4650	regulator
GFK26_11940	COG1690	Belongs to the RtcB family
GFK26_11950	COG0430	RNA-3'-phosphate cyclase activity
GFK26_11960	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_11980	COG0154	amidase activity
GFK26_11985	COG2186	Transcriptional regulator
GFK26_12030	COG5507	3-demethylubiquinone-9 3-methyltransferase
GFK26_12045	COG2764	glyoxalase bleomycin resistance protein dioxygenase
GFK26_12060	COG1960	acyl-CoA dehydrogenase activity
GFK26_12080	COG1024	Enoyl-CoA hydratase
GFK26_12095	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_12115	COG0489	protein tyrosine kinase activity
GFK26_12130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFK26_12140	COG2226	methyltransferase
GFK26_12155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFK26_12160	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GFK26_12195	COG0109	protoheme IX farnesyltransferase activity
GFK26_12200	COG1999	signal sequence binding
GFK26_12205	COG4335	DNA alkylation repair
GFK26_12245	COG0612	Peptidase, M16
GFK26_12250	COG0612	Peptidase, M16
GFK26_12265	COG0742	ribosomal rna small subunit methyltransferase
GFK26_12270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GFK26_12275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GFK26_12280	COG1984	allophanate hydrolase subunit 2
GFK26_12290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFK26_12295	COG2267	carboxylic ester hydrolase activity
GFK26_12300	COG0588	phosphoglycerate mutase activity
GFK26_12305	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_12335	COG0154	amidase activity
GFK26_12340	COG0747	negative chemotaxis
GFK26_12350	COG4608	Belongs to the ABC transporter superfamily
GFK26_12355	COG0444	Belongs to the ABC transporter superfamily
GFK26_12360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_12370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFK26_12380	COG0193	aminoacyl-tRNA hydrolase activity
GFK26_12385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GFK26_12390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFK26_12400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GFK26_12415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GFK26_12420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GFK26_12430	COG1660	Displays ATPase and GTPase activities
GFK26_12435	COG0497	DNA recombination
GFK26_12440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFK26_12445	COG1420	regulation of RNA biosynthetic process
GFK26_12470	COG1074	ATP-dependent DNA helicase activity
GFK26_12620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFK26_12630	COG0210	DNA helicase
GFK26_12670	COG0583	DNA-binding transcription factor activity
GFK26_12685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_12715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFK26_12720	COG1758	RNA polymerase activity
GFK26_12725	COG0194	GDP metabolic process
GFK26_12730	COG1561	YicC-like family, N-terminal region
GFK26_12750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GFK26_12755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFK26_12775	COG1129	ABC transporter
GFK26_12780	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_12785	COG1879	ABC-type sugar transport system periplasmic component
GFK26_12800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFK26_12805	COG2376	Dihydroxyacetone kinase
GFK26_12825	COG2226	methyltransferase
GFK26_12825	COG0596	Alpha beta hydrolase
GFK26_12825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_12830	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_12850	COG1388	LysM domain
GFK26_12850	COG4942	peptidase
GFK26_12895	COG4944	Protein of unknown function (DUF1109)
GFK26_12900	COG1595	DNA-templated transcription, initiation
GFK26_12960	COG3287	FIST C domain
GFK26_12960	COG2199	diguanylate cyclase activity
GFK26_12960	COG2200	EAL domain
GFK26_12965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFK26_12990	COG4771	TonB-dependent receptor
GFK26_12995	COG2814	Major facilitator Superfamily
GFK26_13000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFK26_13040	COG4106	trans-aconitate 2-methyltransferase activity
GFK26_13050	COG2217	Heavy metal translocating P-type atpase
GFK26_13060	COG3278	Belongs to the heme-copper respiratory oxidase family
GFK26_13095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFK26_13110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFK26_13115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_13155	COG1959	2 iron, 2 sulfur cluster binding
GFK26_13170	COG1335	isochorismatase
GFK26_13175	COG1335	isochorismatase
GFK26_13195	COG1283	sodium-dependent phosphate transmembrane transporter activity
GFK26_13200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GFK26_13205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GFK26_13225	COG1609	Transcriptional regulator
GFK26_13230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_13240	COG0196	riboflavin kinase activity
GFK26_13250	COG1024	Enoyl-CoA hydratase
GFK26_13265	COG1960	acyl-CoA dehydrogenase activity
GFK26_13270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFK26_13290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFK26_13290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_13305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GFK26_13310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GFK26_13315	COG0492	ferredoxin-NADP+ reductase activity
GFK26_13325	COG1674	ftsk spoiiie
GFK26_13330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GFK26_13335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFK26_13340	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_13350	COG0411	ABC transporter
GFK26_13410	COG2816	NAD+ diphosphatase activity
GFK26_13415	COG0425	Belongs to the sulfur carrier protein TusA family
GFK26_13440	COG2267	carboxylic ester hydrolase activity
GFK26_13445	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GFK26_13445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GFK26_13450	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_13465	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_13485	COG1960	acyl-CoA dehydrogenase activity
GFK26_13495	COG1960	acyl-CoA dehydrogenase activity
GFK26_13505	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_13535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFK26_13545	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GFK26_13560	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_13565	COG0583	DNA-binding transcription factor activity
GFK26_13570	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFK26_13590	COG1598	PFAM Uncharacterised protein family UPF0150
GFK26_13595	COG1724	mRNA binding
GFK26_13610	COG0583	DNA-binding transcription factor activity
GFK26_13630	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GFK26_13635	COG4221	oxidoreductase activity
GFK26_13660	COG2807	transmembrane transport
GFK26_13665	COG2186	Transcriptional regulator
GFK26_13670	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GFK26_13675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFK26_13680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFK26_13700	COG1280	lysine exporter protein (LysE YggA)
GFK26_13785	COG4566	intracellular signal transduction
GFK26_13790	COG0477	Major facilitator Superfamily
GFK26_13800	COG0165	Argininosuccinate lyase
GFK26_13805	COG3275	phosphorelay sensor kinase activity
GFK26_13815	COG0628	permease
GFK26_13830	COG1733	regulation of RNA biosynthetic process
GFK26_13835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_13850	COG0583	DNA-binding transcription factor activity
GFK26_13875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFK26_13880	COG0181	hydroxymethylbilane synthase activity
GFK26_13885	COG1587	Uroporphyrinogen-III synthase
GFK26_13905	COG0583	DNA-binding transcription factor activity
GFK26_13910	COG1530	ribonuclease E activity
GFK26_13930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFK26_13930	COG0616	signal peptide processing
GFK26_13935	COG2223	nitrite transmembrane transporter activity
GFK26_13945	COG0424	maF-like protein
GFK26_13950	COG1399	metal-binding, possibly nucleic acid-binding protein
GFK26_13955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GFK26_13960	COG0416	fatty acid biosynthetic process
GFK26_13965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFK26_13970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GFK26_13975	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_13980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_13985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFK26_14010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_14015	COG0481	GTPase activity
GFK26_14020	COG0681	Belongs to the peptidase S26 family
GFK26_14030	COG0571	ribonuclease III activity
GFK26_14035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFK26_14040	COG1381	Involved in DNA repair and RecF pathway recombination
GFK26_14045	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GFK26_14050	COG0736	holo-[acyl-carrier-protein] synthase activity
GFK26_14055	COG1472	Belongs to the glycosyl hydrolase 3 family
GFK26_14065	COG1451	nucleotide metabolic process
GFK26_14070	COG0443	Heat shock 70 kDa protein
GFK26_14085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GFK26_14095	COG0762	integral membrane protein
GFK26_14100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GFK26_14105	COG0159	tryptophan synthase activity
GFK26_14110	COG0133	tryptophan synthase activity
GFK26_14115	COG0135	phosphoribosylanthranilate isomerase activity
GFK26_14120	COG0101	tRNA pseudouridine synthase activity
GFK26_14130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFK26_14135	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_14140	COG0066	3-isopropylmalate dehydratase activity
GFK26_14145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFK26_14155	COG0372	Belongs to the citrate synthase family
GFK26_14160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GFK26_14165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GFK26_14170	COG1053	succinate dehydrogenase
GFK26_14185	COG2188	Transcriptional regulator
GFK26_14190	COG0039	L-malate dehydrogenase activity
GFK26_14195	COG4106	trans-aconitate 2-methyltransferase activity
GFK26_14230	COG3468	outer membrane autotransporter barrel domain protein
GFK26_14280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_14295	COG2822	iron ion transport
GFK26_14315	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFK26_14315	COG1918	ferrous iron import across plasma membrane
GFK26_14325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_14340	COG3483	tryptophan 2,3-dioxygenase activity
GFK26_14350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_14355	COG1522	sequence-specific DNA binding
GFK26_14370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GFK26_14375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GFK26_14385	COG0268	Binds directly to 16S ribosomal RNA
GFK26_14390	COG0728	peptidoglycan biosynthetic process
GFK26_14410	COG3795	YCII-related domain
GFK26_14420	COG4941	Belongs to the sigma-70 factor family
GFK26_14425	COG1917	Cupin 2, conserved barrel domain protein
GFK26_14425	COG4977	sequence-specific DNA binding
GFK26_14445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GFK26_14450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFK26_14455	COG0617	tRNA 3'-terminal CCA addition
GFK26_14470	COG1392	Phosphate transport regulator
GFK26_14475	COG0306	phosphate transporter
GFK26_14490	COG0228	four-way junction DNA binding
GFK26_14495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFK26_14500	COG0336	Belongs to the RNA methyltransferase TrmD family
GFK26_14505	COG0335	large ribosomal subunit rRNA binding
GFK26_14510	COG0494	nUDIX hydrolase
GFK26_14515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GFK26_14520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GFK26_14530	COG1162	GTPase activity
GFK26_14535	COG2154	pterin-4-alpha-carbinolamine dehydratase
GFK26_14545	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GFK26_14550	COG0513	Belongs to the DEAD box helicase family
GFK26_14560	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_14565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_14570	COG0604	alcohol dehydrogenase
GFK26_14620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GFK26_14625	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_14630	COG0683	leucine binding
GFK26_14640	COG4638	Rieske (2fe-2S)
GFK26_14645	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GFK26_14655	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_14660	COG0411	ABC transporter
GFK26_14750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GFK26_14760	COG0308	aminopeptidase N
GFK26_14765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_14780	COG1464	Belongs to the NlpA lipoprotein family
GFK26_14785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFK26_14790	COG2011	ABC-type metal ion transport system permease component
GFK26_14795	COG1464	Belongs to the NlpA lipoprotein family
GFK26_14810	COG1464	Belongs to the NlpA lipoprotein family
GFK26_14825	COG0667	Aldo Keto reductase
GFK26_14830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFK26_14835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GFK26_14840	COG0251	oxidation-reduction process
GFK26_14850	COG1666	GTP binding
GFK26_14855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GFK26_14865	COG0137	argininosuccinate synthase activity
GFK26_14870	COG3123	guanosine phosphorylase activity
GFK26_14880	COG1393	Belongs to the ArsC family
GFK26_14885	COG0285	dihydrofolate synthase activity
GFK26_14910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_14970	COG1846	Transcriptional regulator
GFK26_14990	COG0411	ABC transporter
GFK26_15005	COG0683	leucine binding
GFK26_15025	COG0583	DNA-binding transcription factor activity
GFK26_15065	COG1283	sodium-dependent phosphate transmembrane transporter activity
GFK26_15090	COG1126	abc transporter atp-binding protein
GFK26_15095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_15105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_15170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_15180	COG2301	Belongs to the HpcH HpaI aldolase family
GFK26_15185	COG2079	MmgE PrpD family protein
GFK26_15200	COG2030	dehydratase
GFK26_15205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_15210	COG2301	Belongs to the HpcH HpaI aldolase family
GFK26_15215	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15220	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_15220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFK26_15220	COG1042	CoA-binding domain protein
GFK26_15235	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_15240	COG0183	Belongs to the thiolase family
GFK26_15245	COG1960	acyl-CoA dehydrogenase activity
GFK26_15250	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_15255	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_15260	COG1960	acyl-CoA dehydrogenase activity
GFK26_15285	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15315	COG0583	DNA-binding transcription factor activity
GFK26_15330	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_15335	COG1960	acyl-CoA dehydrogenase activity
GFK26_15345	COG1024	Enoyl-CoA hydratase
GFK26_15355	COG1960	acyl-CoA dehydrogenase activity
GFK26_15360	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_15365	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15375	COG1960	acyl-CoA dehydrogenase activity
GFK26_15380	COG0183	Belongs to the thiolase family
GFK26_15385	COG1960	acyl-CoA dehydrogenase activity
GFK26_15400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_15405	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_15410	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15415	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_15420	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_15440	COG1960	acyl-CoA dehydrogenase activity
GFK26_15445	COG2197	response regulator
GFK26_15455	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15460	COG1024	Enoyl-CoA hydratase
GFK26_15465	COG1960	acyl-CoA dehydrogenase activity
GFK26_15470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_15525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_15535	COG0583	DNA-binding transcription factor activity
GFK26_15555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_15580	COG0582	viral genome integration into host DNA
GFK26_15590	COG2072	flavoprotein involved in K transport
GFK26_15600	COG2144	transferase activity, transferring acyl groups
GFK26_15610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFK26_15625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_15640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_15665	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_15690	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_15750	COG3251	PFAM MbtH domain protein
GFK26_15770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFK26_15780	COG4774	siderophore transport
GFK26_15785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFK26_15810	COG0625	glutathione transferase activity
GFK26_15830	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_15850	COG0697	spore germination
GFK26_15860	COG2169	Transcriptional regulator
GFK26_15885	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFK26_15890	COG1309	transcriptional regulator
GFK26_15895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_15925	COG0259	pyridoxamine-phosphate oxidase activity
GFK26_15930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_15955	COG1609	Transcriptional regulator
GFK26_15960	COG3265	gluconokinase activity
GFK26_15965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_15970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_15975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_15985	COG0800	Aldolase
GFK26_16000	COG0346	lactoylglutathione lyase activity
GFK26_16010	COG3842	ATPase activity
GFK26_16020	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_16050	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_16060	COG0235	Class ii aldolase
GFK26_16065	COG0800	Aldolase
GFK26_16070	COG3734	2-keto-3-deoxy-galactonokinase
GFK26_16075	COG0129	dihydroxy-acid dehydratase activity
GFK26_16080	COG2186	Transcriptional regulator
GFK26_16085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_16090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_16095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_16115	COG0513	Belongs to the DEAD box helicase family
GFK26_16120	COG0488	(ABC) transporter
GFK26_16135	COG3191	aminopeptidase activity
GFK26_16160	COG2132	Multicopper oxidase
GFK26_16180	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_16200	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GFK26_16205	COG0583	DNA-binding transcription factor activity
GFK26_16215	COG0765	amino acid transport
GFK26_16220	COG0765	amino acid transport
GFK26_16235	COG2271	Major facilitator Superfamily
GFK26_16260	COG1764	response to oxidative stress
GFK26_16270	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_16280	COG0300	oxidoreductase activity
GFK26_16285	COG1595	DNA-templated transcription, initiation
GFK26_16290	COG3712	iron ion homeostasis
GFK26_16295	COG4773	Receptor
GFK26_16330	COG3246	L-lysine catabolic process to acetate
GFK26_16340	COG3485	protocatechuate 3,4-dioxygenase
GFK26_16350	COG1525	nuclease
GFK26_16360	COG1252	NADH dehydrogenase
GFK26_16365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFK26_16370	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GFK26_16380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFK26_16385	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_16390	COG1129	ABC transporter
GFK26_16395	COG1879	ABC-type sugar transport system periplasmic component
GFK26_16400	COG1984	allophanate hydrolase subunit 2
GFK26_16415	COG0511	ligase activity, forming carbon-carbon bonds
GFK26_16425	COG0583	DNA-binding transcription factor activity
GFK26_16440	COG0589	response to stress
GFK26_16445	COG0564	pseudouridine synthase activity
GFK26_16460	COG4628	conserved protein (DUF2132)
GFK26_16470	COG2354	Protein conserved in bacteria
GFK26_16495	COG0477	Major facilitator Superfamily
GFK26_16510	COG4774	siderophore transport
GFK26_16545	COG0523	cobalamin synthesis protein
GFK26_16570	COG2918	glutathione biosynthetic process
GFK26_16575	COG2201	protein-glutamate methylesterase activity
GFK26_16580	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_16590	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GFK26_16590	COG0517	IMP dehydrogenase activity
GFK26_16600	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFK26_16610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFK26_16615	COG1131	(ABC) transporter
GFK26_16630	COG4774	siderophore transport
GFK26_16655	COG0004	ammonium transporteR
GFK26_16660	COG3177	Filamentation induced by cAMP protein fic
GFK26_16700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_16715	COG3275	phosphorelay sensor kinase activity
GFK26_16730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_16750	COG1538	Outer membrane efflux protein
GFK26_16780	COG1737	Transcriptional regulator
GFK26_16785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFK26_16790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_16805	COG1968	undecaprenyl-diphosphatase activity
GFK26_16825	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GFK26_16830	COG4585	Histidine kinase
GFK26_16840	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_16845	COG3795	YCII-related domain
GFK26_16850	COG4941	Belongs to the sigma-70 factor family
GFK26_16870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFK26_16885	COG0598	Magnesium transport protein CorA
GFK26_16890	COG2375	cellular response to nickel ion
GFK26_16895	COG1695	Transcriptional regulator
GFK26_16900	COG2205	protein histidine kinase activity
GFK26_16900	COG5002	protein histidine kinase activity
GFK26_16900	COG0784	Response regulator, receiver
GFK26_16920	COG2274	protein secretion by the type I secretion system
GFK26_16940	COG2205	protein histidine kinase activity
GFK26_16940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_16970	COG3119	arylsulfatase activity
GFK26_16995	COG0583	DNA-binding transcription factor activity
GFK26_17005	COG2311	Membrane
GFK26_17025	COG1522	sequence-specific DNA binding
GFK26_17045	COG1289	transmembrane transporter activity
GFK26_17060	COG1045	serine acetyltransferase
GFK26_17065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFK26_17090	COG0789	Transcriptional regulator
GFK26_17115	COG0475	glutathione-regulated potassium exporter activity
GFK26_17175	COG0521	Mo-molybdopterin cofactor biosynthetic process
GFK26_17185	COG0312	modulator of DNA gyrase
GFK26_17205	COG0395	ABC-type sugar transport system, permease component
GFK26_17210	COG3842	ATPase activity
GFK26_17215	COG1063	alcohol dehydrogenase
GFK26_17220	COG0300	oxidoreductase activity
GFK26_17225	COG2072	flavoprotein involved in K transport
GFK26_17230	COG0385	Bile acid
GFK26_17235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_17250	COG0494	nUDIX hydrolase
GFK26_17260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GFK26_17265	COG2081	HI0933 family
GFK26_17270	COG0791	NLP P60 protein
GFK26_17285	COG3220	belongs to the UPF0276 family
GFK26_17315	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_17325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFK26_17330	COG0243	molybdopterin cofactor binding
GFK26_17340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFK26_17350	COG2223	nitrite transmembrane transporter activity
GFK26_17360	COG1116	anion transmembrane transporter activity
GFK26_17365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_17370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_17375	COG3707	response regulator
GFK26_17380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GFK26_17395	COG0683	leucine binding
GFK26_17415	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GFK26_17420	COG1185	polyribonucleotide nucleotidyltransferase activity
GFK26_17430	COG0149	triose-phosphate isomerase activity
GFK26_17445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_17450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_17455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_17460	COG0649	NAD binding
GFK26_17475	COG1034	ATP synthesis coupled electron transport
GFK26_17480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GFK26_17485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFK26_17495	COG0713	ATP synthesis coupled electron transport
GFK26_17510	COG1007	ATP synthesis coupled electron transport
GFK26_17520	COG0494	nUDIX hydrolase
GFK26_17530	COG1132	(ABC) transporter
GFK26_17535	COG1846	Transcriptional regulator
GFK26_17545	COG1566	PFAM secretion protein HlyD family protein
GFK26_17585	COG3501	Rhs element vgr protein
GFK26_17615	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_17660	COG4941	Belongs to the sigma-70 factor family
GFK26_17665	COG3795	YCII-related domain
GFK26_17680	COG2186	Transcriptional regulator
GFK26_17690	COG4181	ATPase activity
GFK26_17695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GFK26_17700	COG2207	Transcriptional regulator
GFK26_17730	COG0477	Major facilitator Superfamily
GFK26_17745	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_17750	COG2271	Major facilitator Superfamily
GFK26_17755	COG0583	DNA-binding transcription factor activity
GFK26_17765	COG0586	Pfam SNARE associated Golgi protein
GFK26_17775	COG0789	Transcriptional regulator
GFK26_17780	COG2226	methyltransferase
GFK26_17790	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFK26_17795	COG0802	atpase or kinase
GFK26_17800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFK26_17815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GFK26_17820	COG4774	siderophore transport
GFK26_17825	COG3214	Protein conserved in bacteria
GFK26_17840	COG0673	inositol 2-dehydrogenase activity
GFK26_17855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_17860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_17870	COG1309	transcriptional regulator
GFK26_17875	COG0028	Belongs to the TPP enzyme family
GFK26_17885	COG2207	Transcriptional regulator
GFK26_17915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFK26_17920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFK26_17925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GFK26_17930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GFK26_17935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GFK26_17940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_17940	COG0072	phenylalanine-tRNA ligase activity
GFK26_17945	COG0776	regulation of translation
GFK26_18015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFK26_18015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFK26_18020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFK26_18055	COG0419	ATPase involved in DNA repair
GFK26_18080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFK26_18220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFK26_18305	COG1690	Belongs to the RtcB family
GFK26_18410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFK26_18415	COG1475	DNA binding
GFK26_18535	COG3941	tape measure
GFK26_18615	COG1702	phosphate starvation-inducible protein PhoH
GFK26_18650	COG0358	DNA primase activity
GFK26_18680	COG0194	GDP metabolic process
GFK26_18700	COG0582	viral genome integration into host DNA
GFK26_18720	COG0583	DNA-binding transcription factor activity
GFK26_18740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_18750	COG0183	Belongs to the thiolase family
GFK26_18765	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_18780	COG2003	Belongs to the UPF0758 family
GFK26_18790	COG1475	DNA binding
GFK26_18800	COG5489	Protein of unknown function (DUF736)
GFK26_18840	COG1192	Involved in chromosome partitioning
GFK26_18865	COG1104	cysteine desulfurase activity
GFK26_18895	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_18920	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_18930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_18965	COG2267	carboxylic ester hydrolase activity
GFK26_18970	COG2072	flavoprotein involved in K transport
GFK26_18975	COG2271	Major facilitator Superfamily
GFK26_19000	COG2368	4-hydroxyphenylacetate
GFK26_19020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFK26_19045	COG2315	Protein conserved in bacteria
GFK26_19055	COG0583	DNA-binding transcription factor activity
GFK26_19060	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19085	COG1414	Transcriptional regulator
GFK26_19100	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19110	COG1960	acyl-CoA dehydrogenase activity
GFK26_19115	COG1024	Enoyl-CoA hydratase
GFK26_19120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_19145	COG1024	Enoyl-CoA hydratase
GFK26_19155	COG0778	Nitroreductase
GFK26_19160	COG0667	Aldo Keto reductase
GFK26_19165	COG2272	Belongs to the type-B carboxylesterase lipase family
GFK26_19170	COG1024	Enoyl-CoA hydratase
GFK26_19200	COG2706	6-phosphogluconolactonase activity
GFK26_19205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_19230	COG0583	DNA-binding transcription factor activity
GFK26_19245	COG4962	Type ii secretion system protein e
GFK26_19260	COG3451	type IV secretory pathway VirB4
GFK26_19275	COG3846	protein secretion by the type IV secretion system
GFK26_19300	COG1484	DNA-dependent DNA replication
GFK26_19305	COG4584	PFAM Integrase catalytic
GFK26_19335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_19345	COG0672	)-iron permease
GFK26_19360	COG0789	Transcriptional regulator
GFK26_19370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFK26_19420	COG0582	viral genome integration into host DNA
GFK26_19450	COG1595	DNA-templated transcription, initiation
GFK26_19455	COG3712	iron ion homeostasis
GFK26_19465	COG0583	DNA-binding transcription factor activity
GFK26_19475	COG3693	PFAM glycoside hydrolase, family 10
GFK26_19490	COG0864	Transcriptional regulator
GFK26_19525	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_19545	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19555	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19560	COG1609	Transcriptional regulator
GFK26_19575	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_19580	COG0730	response to heat
GFK26_19610	COG1473	amidohydrolase
GFK26_19615	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_19620	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19645	COG0583	DNA-binding transcription factor activity
GFK26_19650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_19660	COG1960	acyl-CoA dehydrogenase activity
GFK26_19670	COG1024	Enoyl-CoA hydratase
GFK26_19675	COG1042	CoA-binding domain protein
GFK26_19675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFK26_19675	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_19690	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GFK26_19695	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_19700	COG0583	DNA-binding transcription factor activity
GFK26_19705	COG2031	fatty acid transporter
GFK26_19715	COG2423	ornithine cyclodeaminase activity
GFK26_19720	COG0583	DNA-binding transcription factor activity
GFK26_19740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_19775	COG0417	DNA replication proofreading
GFK26_19780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFK26_19795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFK26_19805	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GFK26_19810	COG5002	protein histidine kinase activity
GFK26_19815	COG0392	lysyltransferase activity
GFK26_19840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFK26_19925	COG1522	sequence-specific DNA binding
GFK26_19945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFK26_19950	COG0006	proline dipeptidase activity
GFK26_19985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_19995	COG2197	response regulator
GFK26_20015	COG1595	DNA-templated transcription, initiation
GFK26_20030	COG1960	acyl-CoA dehydrogenase activity
GFK26_20040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_20055	COG4964	Belongs to the GSP D family
GFK26_20110	COG2197	response regulator
GFK26_20125	COG0778	Nitroreductase
GFK26_20130	COG3501	Rhs element vgr protein
GFK26_20150	COG3501	Rhs element vgr protein
GFK26_20155	COG3209	COG3209 Rhs family protein
GFK26_20195	COG1360	Flagellar Motor Protein
GFK26_20210	COG1742	UPF0060 membrane protein
GFK26_20220	COG1132	(ABC) transporter
GFK26_20225	COG3145	DNA-N1-methyladenine dioxygenase activity
GFK26_20260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_20295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_20305	COG3045	CreA protein
GFK26_20340	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFK26_20345	COG0183	Belongs to the thiolase family
GFK26_20355	COG0583	DNA-binding transcription factor activity
GFK26_20360	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_20365	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GFK26_20390	COG1546	Belongs to the CinA family
GFK26_20390	COG1058	Belongs to the CinA family
GFK26_20400	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_20405	COG1301	dicarboxylic acid transport
GFK26_20410	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GFK26_20415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFK26_20415	COG4651	solute:proton antiporter activity
GFK26_20430	COG4774	siderophore transport
GFK26_20475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFK26_20510	COG2076	Multidrug Resistance protein
GFK26_20525	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFK26_20530	COG0583	DNA-binding transcription factor activity
GFK26_20565	COG3712	iron ion homeostasis
GFK26_20570	COG1595	DNA-templated transcription, initiation
GFK26_20605	COG3813	Protein conserved in bacteria
GFK26_20635	COG1522	sequence-specific DNA binding
GFK26_20640	COG0028	Belongs to the TPP enzyme family
GFK26_20650	COG4172	Belongs to the ABC transporter superfamily
GFK26_20665	COG4166	transmembrane transport
GFK26_20680	COG1802	Transcriptional regulator
GFK26_20780	COG2003	Belongs to the UPF0758 family
GFK26_20795	COG5489	Protein of unknown function (DUF736)
GFK26_20855	COG1192	Involved in chromosome partitioning
GFK26_20880	COG0583	DNA-binding transcription factor activity
GFK26_20885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GFK26_20895	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_20935	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_20980	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_21040	COG3246	L-lysine catabolic process to acetate
GFK26_21045	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_21060	COG1309	transcriptional regulator
GFK26_21090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_21095	COG0583	DNA-binding transcription factor activity
GFK26_21125	COG1414	Transcriptional regulator
GFK26_21130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_21135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_21160	COG0235	Class ii aldolase
GFK26_21165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_21170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_21185	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_21190	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_21195	COG0410	ABC transporter
GFK26_21210	COG1063	alcohol dehydrogenase
GFK26_21230	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_21255	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GFK26_21270	COG1414	Transcriptional regulator
GFK26_21275	COG1024	Enoyl-CoA hydratase
GFK26_21280	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_21290	COG1960	acyl-CoA dehydrogenase activity
GFK26_21295	COG1960	acyl-CoA dehydrogenase activity
GFK26_21300	COG1063	alcohol dehydrogenase
GFK26_21305	COG1414	Transcriptional regulator
GFK26_21310	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_21335	COG1137	ATPase activity
GFK26_21350	COG0596	Alpha beta hydrolase
GFK26_21360	COG3246	L-lysine catabolic process to acetate
GFK26_21375	COG1024	Enoyl-CoA hydratase
GFK26_21380	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_21385	COG2050	protein possibly involved in aromatic compounds catabolism
GFK26_21390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_21395	COG1063	alcohol dehydrogenase
GFK26_21405	COG1960	acyl-CoA dehydrogenase activity
GFK26_21425	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_21440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_21445	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_21450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_21460	COG0765	amino acid transport
GFK26_21525	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFK26_21560	COG3246	L-lysine catabolic process to acetate
GFK26_21565	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_21570	COG1960	acyl-CoA dehydrogenase activity
GFK26_21575	COG1024	Enoyl-CoA hydratase
GFK26_21585	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_21595	COG1063	alcohol dehydrogenase
GFK26_21610	COG0411	ABC transporter
GFK26_21615	COG0410	ABC transporter
GFK26_21645	COG4372	Transposase
GFK26_21650	COG3436	PFAM IS66 Orf2 family protein
GFK26_21665	COG3618	amidohydrolase
GFK26_21670	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_21675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_21705	COG0596	Alpha beta hydrolase
GFK26_21730	COG0583	DNA-binding transcription factor activity
GFK26_21745	COG4962	Type ii secretion system protein e
GFK26_21760	COG3451	type IV secretory pathway VirB4
GFK26_21790	COG2948	multi-organism process
GFK26_21830	COG2706	6-phosphogluconolactonase activity
GFK26_21835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFK26_21870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFK26_21880	COG1802	Transcriptional regulator
GFK26_21895	COG1703	isobutyryl-CoA mutase activity
GFK26_21900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFK26_21905	COG0439	Biotin carboxylase
GFK26_21910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GFK26_21920	COG1522	sequence-specific DNA binding
GFK26_21925	COG0697	spore germination
GFK26_21935	COG2878	Part of a membrane complex involved in electron transport
GFK26_21955	COG1959	2 iron, 2 sulfur cluster binding
GFK26_21960	COG1104	cysteine desulfurase activity
GFK26_21965	COG0822	iron-sulfur transferase activity
GFK26_21975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GFK26_21980	COG0443	Heat shock 70 kDa protein
GFK26_22000	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GFK26_22010	COG2197	response regulator
GFK26_22015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFK26_22020	COG0297	glycogen (starch) synthase activity
GFK26_22050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_22055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFK26_22060	COG0489	protein tyrosine kinase activity
GFK26_22060	COG3206	protein involved in exopolysaccharide biosynthesis
GFK26_22065	COG1596	polysaccharide export
GFK26_22100	COG0579	oxidoreductase
GFK26_22115	COG0167	dihydroorotate dehydrogenase activity
GFK26_22120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GFK26_22135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFK26_22140	COG4566	intracellular signal transduction
GFK26_22150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GFK26_22155	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFK26_22165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_22170	COG0791	NLP P60 protein
GFK26_22175	COG2133	pyrroloquinoline quinone binding
GFK26_22185	COG2368	4-hydroxyphenylacetate
GFK26_22205	COG0567	Dehydrogenase, E1 component
GFK26_22210	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFK26_22215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFK26_22220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GFK26_22240	COG1199	ATP-dependent helicase activity
GFK26_22250	COG0564	pseudouridine synthase activity
GFK26_22255	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFK26_22260	COG1187	pseudouridine synthase activity
GFK26_22265	COG0105	UTP biosynthetic process
GFK26_22270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GFK26_22285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GFK26_22290	COG0124	histidyl-tRNA synthetase
GFK26_22300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_22305	COG1160	GTP binding
GFK26_22310	COG1923	regulation of RNA biosynthetic process
GFK26_22315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFK26_22320	COG0330	HflC and HflK could
GFK26_22325	COG0330	HflC and HflK could
GFK26_22335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GFK26_22340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFK26_22360	COG0501	Belongs to the peptidase M48B family
GFK26_22365	COG0626	cystathionine gamma-synthase activity
GFK26_22380	COG4181	ATPase activity
GFK26_22395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFK26_22400	COG0644	oxidoreductase
GFK26_22415	COG0667	Aldo Keto reductase
GFK26_22420	COG2059	Chromate
GFK26_22430	COG1295	ribonuclease BN
GFK26_22450	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_22490	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_22510	COG1024	Enoyl-CoA hydratase
GFK26_22555	COG0625	glutathione transferase activity
GFK26_22565	COG0492	ferredoxin-NADP+ reductase activity
GFK26_22575	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GFK26_22590	COG0248	Ppx GppA phosphatase
GFK26_22595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFK26_22600	COG0573	inorganic phosphate transmembrane transporter activity
GFK26_22605	COG0581	inorganic phosphate transmembrane transporter activity
GFK26_22610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFK26_22625	COG5002	protein histidine kinase activity
GFK26_22630	COG0534	Mate efflux family protein
GFK26_22640	COG0254	rRNA binding
GFK26_22645	COG0673	inositol 2-dehydrogenase activity
GFK26_22650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GFK26_22685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFK26_22690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GFK26_22695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFK26_22705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_22715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_22720	COG0475	glutathione-regulated potassium exporter activity
GFK26_22720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFK26_22725	COG1388	LysM domain
GFK26_22725	COG0741	lytic transglycosylase activity
GFK26_22730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_22740	COG0328	RNA-DNA hybrid ribonuclease activity
GFK26_22750	COG0746	molybdenum cofactor guanylyltransferase activity
GFK26_22755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFK26_22775	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_22785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_22845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_22900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GFK26_22925	COG0028	Belongs to the TPP enzyme family
GFK26_22930	COG0440	acetolactate synthase activity
GFK26_22935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GFK26_22940	COG1183	phosphatidylcholine synthase activity
GFK26_22945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_22950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_22960	COG1414	Transcriptional regulator
GFK26_22965	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GFK26_22970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GFK26_22980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFK26_22980	COG2207	Transcriptional regulator
GFK26_23000	COG1414	Transcriptional regulator
GFK26_23005	COG0745	RESPONSE REGULATOR receiver
GFK26_23010	COG0642	Histidine kinase
GFK26_23015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFK26_23035	COG2267	carboxylic ester hydrolase activity
GFK26_23050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFK26_23055	COG0154	amidase activity
GFK26_23060	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_23135	COG2022	thiamine diphosphate biosynthetic process
GFK26_23150	COG0351	phosphomethylpyrimidine kinase
GFK26_23160	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GFK26_23195	COG0492	ferredoxin-NADP+ reductase activity
GFK26_23200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GFK26_23205	COG0529	Catalyzes the synthesis of activated sulfate
GFK26_23205	COG2895	sulfate adenylyltransferase (ATP) activity
GFK26_23215	COG0175	sulfate reduction
GFK26_23230	COG0840	transmembrane signaling receptor activity
GFK26_23245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_23250	COG0601	transmembrane transport
GFK26_23260	COG0747	negative chemotaxis
GFK26_23265	COG4172	Belongs to the ABC transporter superfamily
GFK26_23270	COG1446	asparaginase
GFK26_23290	COG0789	Transcriptional regulator
GFK26_23310	COG0667	Aldo Keto reductase
GFK26_23315	COG0583	DNA-binding transcription factor activity
GFK26_23320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_23330	COG0251	oxidation-reduction process
GFK26_23335	COG0583	DNA-binding transcription factor activity
GFK26_23340	COG0427	acetyl-CoA hydrolase
GFK26_23350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_23355	COG1879	ABC-type sugar transport system periplasmic component
GFK26_23370	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFK26_23390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_23400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFK26_23405	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GFK26_23410	COG0745	RESPONSE REGULATOR receiver
GFK26_23415	COG5002	protein histidine kinase activity
GFK26_23435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GFK26_23435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_23440	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GFK26_23450	COG0431	NADPH-dependent FMN reductase
GFK26_23460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_23465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_23470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_23475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_23480	COG1116	anion transmembrane transporter activity
GFK26_23505	COG1045	serine acetyltransferase
GFK26_23515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_23520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFK26_23535	COG3550	peptidyl-serine autophosphorylation
GFK26_23545	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFK26_23565	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_23570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GFK26_23580	COG0450	alkyl hydroperoxide reductase
GFK26_23590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GFK26_23600	COG4208	sulfate ABC transporter
GFK26_23605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GFK26_23610	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GFK26_23615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_23625	COG1538	Outer membrane efflux protein
GFK26_23645	COG2226	methyltransferase
GFK26_23650	COG0217	transcriptional regulatory protein
GFK26_23655	COG0151	Belongs to the GarS family
GFK26_23660	COG0408	coproporphyrinogen oxidase activity
GFK26_23665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFK26_23670	COG0799	negative regulation of ribosome biogenesis
GFK26_23675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GFK26_23680	COG0424	maF-like protein
GFK26_23685	COG1530	ribonuclease E activity
GFK26_23695	COG3246	L-lysine catabolic process to acetate
GFK26_23700	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_23705	COG1802	Transcriptional regulator
GFK26_23710	COG1132	(ABC) transporter
GFK26_23715	COG0823	Involved in the tonB-independent uptake of proteins
GFK26_23730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GFK26_23740	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_23745	COG1024	Enoyl-CoA hydratase
GFK26_23770	COG1960	acyl-CoA dehydrogenase activity
GFK26_23775	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_23785	COG2070	2-Nitropropane dioxygenase
GFK26_23790	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_23825	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_23830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_23840	COG2171	N-acyltransferase activity
GFK26_23855	COG1280	lysine exporter protein (LysE YggA)
GFK26_23860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GFK26_23860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GFK26_23865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_23870	COG1643	Atp-dependent helicase
GFK26_23885	COG0436	Aminotransferase
GFK26_23890	COG0583	DNA-binding transcription factor activity
GFK26_23910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GFK26_23945	COG0784	Response regulator, receiver
GFK26_23945	COG2205	protein histidine kinase activity
GFK26_23960	COG3121	Chaperone
GFK26_23995	COG2205	protein histidine kinase activity
GFK26_23995	COG0784	Response regulator, receiver
GFK26_24000	COG3204	pilus organization
GFK26_24020	COG1982	Orn Lys Arg decarboxylase major
GFK26_24025	COG1793	dna ligase
GFK26_24035	COG4166	transmembrane transport
GFK26_24040	COG4174	ABC transporter (Permease)
GFK26_24045	COG4239	(ABC) transporter, permease
GFK26_24050	COG4172	Belongs to the ABC transporter superfamily
GFK26_24055	COG0477	Major facilitator Superfamily
GFK26_24060	COG0779	Required for maturation of 30S ribosomal subunits
GFK26_24065	COG2251	uridine kinase activity
GFK26_24065	COG0195	Participates in both transcription termination and antitermination
GFK26_24070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GFK26_24075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFK26_24080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GFK26_24115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GFK26_24120	COG2867	negative regulation of translational initiation
GFK26_24150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFK26_24150	COG0519	Catalyzes the synthesis of GMP from XMP
GFK26_24190	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_24210	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_24240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFK26_24250	COG1744	ABC transporter substrate-binding protein PnrA-like
GFK26_24255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GFK26_24280	COG1595	DNA-templated transcription, initiation
GFK26_24290	COG0433	COG0433 Predicted ATPase
GFK26_24305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_24350	COG3550	peptidyl-serine autophosphorylation
GFK26_24365	COG1196	nuclear chromosome segregation
GFK26_24375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GFK26_24385	COG0242	peptide deformylase activity
GFK26_24395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFK26_24400	COG4597	amino acid ABC transporter
GFK26_24405	COG0765	amino acid transport
GFK26_24410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFK26_24425	COG2197	response regulator
GFK26_24435	COG0457	Tetratricopeptide repeat
GFK26_24440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GFK26_24445	COG1215	transferase activity, transferring glycosyl groups
GFK26_24450	COG1215	transferase activity, transferring glycosyl groups
GFK26_24455	COG2894	cell division
GFK26_24470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GFK26_24475	COG0024	Methionine aminopeptidase
GFK26_24480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFK26_24480	COG0047	phosphoribosylformylglycinamidine synthase activity
GFK26_24505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_24515	COG2917	probably involved in intracellular septation
GFK26_24520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFK26_24525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GFK26_24535	COG2272	Belongs to the type-B carboxylesterase lipase family
GFK26_24540	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_24555	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_24565	COG0411	ABC transporter
GFK26_24575	COG1024	Enoyl-CoA hydratase
GFK26_24575	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_24580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_24585	COG0183	Belongs to the thiolase family
GFK26_24595	COG1960	acyl-CoA dehydrogenase activity
GFK26_24625	COG2130	NADP-dependent
GFK26_24630	COG1960	acyl-CoA dehydrogenase activity
GFK26_24650	COG0583	DNA-binding transcription factor activity
GFK26_24655	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GFK26_24675	COG2814	Major facilitator Superfamily
GFK26_24680	COG0583	DNA-binding transcription factor activity
GFK26_24700	COG1802	Transcriptional regulator
GFK26_24705	COG0277	FAD linked oxidase domain protein
GFK26_24705	COG0247	lactate metabolic process
GFK26_24740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFK26_24750	COG0583	DNA-binding transcription factor activity
GFK26_24765	COG2814	Major facilitator Superfamily
GFK26_24770	COG2814	Major facilitator Superfamily
GFK26_24775	COG2995	paraquat-inducible protein a
GFK26_24780	COG2995	paraquat-inducible protein a
GFK26_24785	COG3008	intermembrane lipid transfer
GFK26_24785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFK26_24795	COG0477	Major facilitator Superfamily
GFK26_24810	COG1595	DNA-templated transcription, initiation
GFK26_24815	COG3712	iron ion homeostasis
GFK26_24820	COG4774	siderophore transport
GFK26_24830	COG0534	Mate efflux family protein
GFK26_24870	COG2201	protein-glutamate methylesterase activity
GFK26_24875	COG4585	Histidine kinase
GFK26_24880	COG2183	response to ionizing radiation
GFK26_24920	COG3501	Rhs element vgr protein
GFK26_24955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFK26_24960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GFK26_24975	COG0084	hydrolase, TatD family'
GFK26_24980	COG0666	response to abiotic stimulus
GFK26_25010	COG2197	response regulator
GFK26_25015	COG2197	response regulator
GFK26_25020	COG0251	oxidation-reduction process
GFK26_25030	COG0590	tRNA wobble adenosine to inosine editing
GFK26_25035	COG2351	hydroxyisourate hydrolase activity
GFK26_25055	COG0583	DNA-binding transcription factor activity
GFK26_25065	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_25070	COG1473	amidohydrolase
GFK26_25075	COG2207	Transcriptional regulator
GFK26_25100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFK26_25100	COG1042	CoA-binding domain protein
GFK26_25100	COG0045	succinate-CoA ligase (ADP-forming) activity
GFK26_25115	COG3360	Dodecin
GFK26_25120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_25125	COG0154	amidase activity
GFK26_25135	COG2207	Transcriptional regulator
GFK26_25140	COG0667	Aldo Keto reductase
GFK26_25145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GFK26_25160	COG3501	Rhs element vgr protein
GFK26_25205	COG0784	Response regulator, receiver
GFK26_25205	COG5002	protein histidine kinase activity
GFK26_25210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFK26_25220	COG5002	protein histidine kinase activity
GFK26_25250	COG1619	proteins homologs of microcin C7 resistance protein MccF
GFK26_25255	COG0590	tRNA wobble adenosine to inosine editing
GFK26_25265	COG2808	Putative FMN-binding domain
GFK26_25280	COG4566	intracellular signal transduction
GFK26_25285	COG4191	Histidine kinase
GFK26_25310	COG2925	Exonuclease
GFK26_25315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_25320	COG0542	response to heat
GFK26_25325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GFK26_25360	COG2885	chlorophyll binding
GFK26_25360	COG3047	cAMP biosynthetic process
GFK26_25430	COG0811	peptide transport
GFK26_25435	COG0848	biopolymer transport protein
GFK26_25440	COG1663	tetraacyldisaccharide 4'-kinase activity
GFK26_25445	COG2835	tetraacyldisaccharide 4'-kinase activity
GFK26_25450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GFK26_25455	COG0563	adenylate kinase activity
GFK26_25460	COG0252	asparaginase activity
GFK26_25465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFK26_25475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_25485	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFK26_25490	COG1024	Enoyl-CoA hydratase
GFK26_25495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_25515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFK26_25525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFK26_25530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GFK26_25535	COG1534	Rna-binding protein
GFK26_25550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFK26_25560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GFK26_25565	COG0505	Belongs to the CarA family
GFK26_25570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFK26_25575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFK26_25580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_25585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_25590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_25595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_25605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFK26_25610	COG0750	zinc metalloprotease
GFK26_25615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GFK26_25620	COG0575	Belongs to the CDS family
GFK26_25625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFK26_25630	COG0233	cytoplasmic translational termination
GFK26_25635	COG0528	UMP kinase activity
GFK26_25640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GFK26_25645	COG0052	Belongs to the universal ribosomal protein uS2 family
GFK26_25665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GFK26_25665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GFK26_25670	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_25675	COG0557	exoribonuclease II activity
GFK26_25690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFK26_25695	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GFK26_25710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFK26_25735	COG0745	RESPONSE REGULATOR receiver
GFK26_25740	COG2205	protein histidine kinase activity
GFK26_25745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GFK26_25745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GFK26_25750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GFK26_25750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GFK26_25755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFK26_25760	COG0560	Phosphoserine phosphatase
GFK26_25780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_25785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFK26_25800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GFK26_25805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GFK26_25810	COG1492	cobalamin metabolic process
GFK26_25820	COG1538	Outer membrane efflux protein
GFK26_25830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_25850	COG1346	cytolysis
GFK26_25865	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GFK26_25885	COG0778	Nitroreductase
GFK26_25890	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GFK26_25900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFK26_25905	COG4607	ABC-type enterochelin transport system periplasmic component
GFK26_25915	COG1797	cobyrinic acid a,c-diamide synthase activity
GFK26_25935	COG0730	response to heat
GFK26_25950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFK26_25955	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_25975	COG1802	Transcriptional regulator
GFK26_25980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GFK26_25995	COG0583	DNA-binding transcription factor activity
GFK26_26000	COG0583	DNA-binding transcription factor activity
GFK26_26005	COG0129	dihydroxy-acid dehydratase activity
GFK26_26020	COG4654	Cytochrome c, class I
GFK26_26030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFK26_26040	COG0583	DNA-binding transcription factor activity
GFK26_26045	COG2910	NAD(P)H-binding
GFK26_26050	COG0114	fumarate hydratase activity
GFK26_26055	COG4175	Glycine betaine
GFK26_26060	COG4176	ABC-type proline glycine betaine transport system permease component
GFK26_26065	COG2113	Glycine betaine
GFK26_26110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GFK26_26115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFK26_26120	COG0740	serine-type endopeptidase activity
GFK26_26125	COG0544	peptidyl-prolyl cis-trans isomerase activity
GFK26_26140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_26155	COG1562	ergosterol biosynthetic process
GFK26_26160	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GFK26_26170	COG1280	lysine exporter protein (LysE YggA)
GFK26_26180	COG1011	Hydrolase
GFK26_26185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GFK26_26190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFK26_26215	COG0410	ABC transporter
GFK26_26280	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_26290	COG0642	Histidine kinase
GFK26_26300	COG2326	polyphosphate kinase activity
GFK26_26320	COG2207	Transcriptional regulator
GFK26_26355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_26410	COG0527	aspartate kinase activity
GFK26_26415	COG0037	tRNA processing
GFK26_26420	COG0825	malonyl-CoA metabolic process
GFK26_26430	COG0215	cysteine-tRNA ligase activity
GFK26_26445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFK26_26450	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFK26_26475	COG0741	lytic transglycosylase activity
GFK26_26480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFK26_26485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFK26_26490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFK26_26490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFK26_26505	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GFK26_26510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFK26_26515	COG0436	Aminotransferase
GFK26_26520	COG0824	Thioesterase
GFK26_26530	COG0848	biopolymer transport protein
GFK26_26545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GFK26_26545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GFK26_26565	COG1741	Belongs to the pirin family
GFK26_26575	COG2259	Doxx family
GFK26_26580	COG1741	Belongs to the pirin family
GFK26_26590	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GFK26_26590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_26595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFK26_26600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GFK26_26635	COG0477	Major facilitator Superfamily
GFK26_26650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFK26_26675	COG1053	succinate dehydrogenase
GFK26_26675	COG3976	FMN-binding domain protein
GFK26_26675	COG0431	NADPH-dependent FMN reductase
GFK26_26710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_26720	COG0647	UMP catabolic process
GFK26_26725	COG1737	Transcriptional regulator
GFK26_26735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_26740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GFK26_26770	COG0410	ABC transporter
GFK26_26775	COG3842	ATPase activity
GFK26_26795	COG2205	protein histidine kinase activity
GFK26_26795	COG2198	Histidine kinase
GFK26_26795	COG0784	Response regulator, receiver
GFK26_26815	COG0583	DNA-binding transcription factor activity
GFK26_26835	COG0604	alcohol dehydrogenase
GFK26_26840	COG1309	transcriptional regulator
GFK26_26860	COG2271	Major facilitator Superfamily
GFK26_26885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFK26_26905	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GFK26_26910	COG0028	Belongs to the TPP enzyme family
GFK26_26915	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_26920	COG1414	Transcriptional regulator
GFK26_26940	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_26945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_26955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFK26_26975	COG1640	4-alpha-glucanotransferase
GFK26_26980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFK26_26995	COG0366	Alpha amylase catalytic
GFK26_27000	COG0366	Alpha amylase catalytic
GFK26_27005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFK26_27050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_27105	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_27115	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_27140	COG2201	protein-glutamate methylesterase activity
GFK26_27150	COG2204	response regulator
GFK26_27160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_27175	COG0071	Belongs to the small heat shock protein (HSP20) family
GFK26_27190	COG2080	2 iron, 2 sulfur cluster binding
GFK26_27195	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GFK26_27200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFK26_27210	COG5492	domain, Protein
GFK26_27210	COG4932	domain protein
GFK26_27240	COG3196	Protein conserved in bacteria
GFK26_27275	COG0789	Transcriptional regulator
GFK26_27295	COG2175	clavaminate synthase activity
GFK26_27300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_27320	COG0730	response to heat
GFK26_27325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_27330	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFK26_27335	COG4521	taurine ABC transporter
GFK26_27340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFK26_27375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_27380	COG1113	amino acid transport
GFK26_27395	COG2855	membrane
GFK26_27400	COG0583	DNA-binding transcription factor activity
GFK26_27405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_27415	COG0583	DNA-binding transcription factor activity
GFK26_27480	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_27505	COG4221	oxidoreductase activity
GFK26_27510	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_27515	COG1733	regulation of RNA biosynthetic process
GFK26_27520	COG1473	amidohydrolase
GFK26_27570	COG1335	isochorismatase
GFK26_27590	COG0583	DNA-binding transcription factor activity
GFK26_27620	COG0587	DNA-directed DNA polymerase activity
GFK26_27625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFK26_27650	COG3384	dioxygenase
GFK26_27655	COG0583	DNA-binding transcription factor activity
GFK26_27660	COG1132	(ABC) transporter
GFK26_27695	COG1160	GTP binding
GFK26_27700	COG1024	Enoyl-CoA hydratase
GFK26_27710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_27715	COG1272	protein, Hemolysin III
GFK26_27725	COG1960	acyl-CoA dehydrogenase activity
GFK26_27730	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_27735	COG0583	DNA-binding transcription factor activity
GFK26_27745	COG0640	Transcriptional regulator
GFK26_27765	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_27770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_27775	COG0583	DNA-binding transcription factor activity
GFK26_27780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFK26_27780	COG0519	Catalyzes the synthesis of GMP from XMP
GFK26_27785	COG1183	phosphatidylcholine synthase activity
GFK26_27815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_27820	COG2818	Glycosylase
GFK26_27835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFK26_27840	COG0583	DNA-binding transcription factor activity
GFK26_27855	COG1024	Enoyl-CoA hydratase
GFK26_27885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_27905	COG0456	acetyltransferase
GFK26_27910	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_27920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_27925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_27985	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_27990	COG3284	Transcriptional regulator
GFK26_28020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GFK26_28030	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GFK26_28040	COG0545	Peptidyl-prolyl cis-trans isomerase
GFK26_28045	COG0531	amino acid
GFK26_28050	COG4303	Ethanolamine ammonia lyase large subunit
GFK26_28055	COG4302	ethanolamine ammonia-lyase activity
GFK26_28075	COG2194	sulfuric ester hydrolase activity
GFK26_28080	COG0671	phosphoesterase, PA-phosphatase related
GFK26_28090	COG0745	RESPONSE REGULATOR receiver
GFK26_28095	COG0642	Histidine kinase
GFK26_28100	COG0824	Thioesterase
GFK26_28110	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_28125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_28130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_28170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GFK26_28175	COG0509	glycine decarboxylation via glycine cleavage system
GFK26_28180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFK26_28180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GFK26_28205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFK26_28255	COG1473	amidohydrolase
GFK26_28300	COG0477	Major facilitator Superfamily
GFK26_28310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFK26_28315	COG2814	Major facilitator Superfamily
GFK26_28325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFK26_28330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_28335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFK26_28340	COG1414	Transcriptional regulator
GFK26_28375	COG0745	RESPONSE REGULATOR receiver
GFK26_28380	COG0642	Histidine kinase
GFK26_28400	COG0024	Methionine aminopeptidase
GFK26_28450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GFK26_28460	COG0477	Major facilitator Superfamily
GFK26_28465	COG3795	YCII-related domain
GFK26_28470	COG3795	YCII-related domain
GFK26_28485	COG0640	Transcriptional regulator
GFK26_28495	COG1024	Enoyl-CoA hydratase
GFK26_28500	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_28510	COG2030	dehydratase
GFK26_28520	COG0318	PFAM AMP-dependent synthetase and ligase
GFK26_28540	COG1294	oxidase, subunit
GFK26_28545	COG1271	oxidase subunit
GFK26_28550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFK26_28555	COG4988	ABC transporter
GFK26_28570	COG1960	acyl-CoA dehydrogenase activity
GFK26_28585	COG3264	Mechanosensitive ion channel
GFK26_28585	COG1196	nuclear chromosome segregation
GFK26_28595	COG0714	Associated with various cellular activities
GFK26_28610	COG2951	lytic endotransglycosylase activity
GFK26_28640	COG1131	(ABC) transporter
GFK26_28655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFK26_28675	COG0395	ABC-type sugar transport system, permease component
GFK26_28685	COG3842	ATPase activity
GFK26_28690	COG3842	ATPase activity
GFK26_28705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFK26_28720	COG2308	Evidence 4 Homologs of previously reported genes of
GFK26_28760	COG4585	Histidine kinase
GFK26_28765	COG2197	response regulator
GFK26_28790	COG2271	Major facilitator Superfamily
GFK26_28810	COG0583	DNA-binding transcription factor activity
GFK26_28820	COG1024	Enoyl-CoA hydratase
GFK26_28825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_28835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_28850	COG5002	protein histidine kinase activity
GFK26_28855	COG2197	response regulator
GFK26_28865	COG1609	Transcriptional regulator
GFK26_28875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFK26_28885	COG1126	abc transporter atp-binding protein
GFK26_28895	COG0765	amino acid transport
GFK26_28900	COG0765	amino acid transport
GFK26_28940	COG0741	lytic transglycosylase activity
GFK26_28945	COG0187	DNA topoisomerase II activity
GFK26_28950	COG0583	DNA-binding transcription factor activity
GFK26_28965	COG2814	Major facilitator Superfamily
GFK26_28975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_28980	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GFK26_28985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFK26_29000	COG2850	peptidyl-arginine hydroxylation
GFK26_29005	COG1047	Peptidyl-prolyl cis-trans
GFK26_29015	COG0756	dUTP diphosphatase activity
GFK26_29025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFK26_29030	COG0504	CTP synthase activity
GFK26_29035	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GFK26_29045	COG0148	phosphopyruvate hydratase activity
GFK26_29050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GFK26_29060	COG3201	nicotinamide mononucleotide transporter
GFK26_29080	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_29090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GFK26_29100	COG2833	Protein of unknown function (DUF455)
GFK26_29115	COG0183	Belongs to the thiolase family
GFK26_29120	COG1309	transcriptional regulator
GFK26_29125	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_29145	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_29150	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_29155	COG0583	DNA-binding transcription factor activity
GFK26_29160	COG4974	Belongs to the 'phage' integrase family
GFK26_29165	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_29180	COG0789	Transcriptional regulator
GFK26_29190	COG2814	Major facilitator Superfamily
GFK26_29205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFK26_29225	COG0583	DNA-binding transcription factor activity
GFK26_29250	COG0183	Belongs to the thiolase family
GFK26_29255	COG1024	Enoyl-CoA hydratase
GFK26_29260	COG1309	transcriptional regulator
GFK26_29285	COG0410	ABC transporter
GFK26_29290	COG1022	Amp-dependent synthetase and ligase
GFK26_29300	COG0542	response to heat
GFK26_29305	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_29315	COG0314	molybdopterin synthase activity
GFK26_29320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_29330	COG0303	'Molybdopterin
GFK26_29335	COG1763	Mo-molybdopterin cofactor biosynthetic process
GFK26_29340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GFK26_29355	COG0436	Aminotransferase
GFK26_29365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GFK26_29400	COG0305	Participates in initiation and elongation during chromosome replication
GFK26_29405	COG0359	binds to the 23S rRNA
GFK26_29410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GFK26_29415	COG2965	DNA replication, synthesis of RNA primer
GFK26_29420	COG0360	Binds together with S18 to 16S ribosomal RNA
GFK26_29435	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GFK26_29440	COG3634	alkyl hydroperoxide reductase activity
GFK26_29470	COG1477	protein flavinylation
GFK26_29475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFK26_29480	COG4774	siderophore transport
GFK26_29485	COG3128	pkhd-type hydroxylase
GFK26_29515	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GFK26_29520	COG0670	Belongs to the BI1 family
GFK26_29525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFK26_29540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFK26_29545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GFK26_29580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFK26_29595	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_29600	COG0596	Alpha beta hydrolase
GFK26_29605	COG0583	DNA-binding transcription factor activity
GFK26_29615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFK26_29620	COG0322	excinuclease ABC activity
GFK26_29625	COG0405	Gamma-glutamyltransferase
GFK26_29640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFK26_29645	COG1611	Belongs to the LOG family
GFK26_29650	COG1309	transcriptional regulator
GFK26_29660	COG0477	Major facilitator Superfamily
GFK26_29675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFK26_29685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFK26_29690	COG3237	CsbD-like
GFK26_29705	COG0123	including yeast histone deacetylase and acetoin utilization protein
GFK26_29720	COG1959	2 iron, 2 sulfur cluster binding
GFK26_29720	COG1295	ribonuclease BN
GFK26_29730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFK26_29735	COG2814	Major facilitator Superfamily
GFK26_29750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_29755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFK26_29760	COG0583	DNA-binding transcription factor activity
GFK26_29780	COG0410	ABC transporter
GFK26_29810	COG1802	Transcriptional regulator
GFK26_29820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GFK26_29830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFK26_29845	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_29860	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_29870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_29875	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_29880	COG2186	Transcriptional regulator
GFK26_29885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFK26_29895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_29905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_29910	COG2721	sulfolactate sulfo-lyase activity
GFK26_29930	COG0688	phosphatidylethanolamine metabolic process
GFK26_29945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFK26_29950	COG0443	Heat shock 70 kDa protein
GFK26_29955	COG0484	heat shock protein binding
GFK26_29960	COG2766	serine protein kinase
GFK26_29965	COG2718	Belongs to the UPF0229 family
GFK26_29970	COG2719	SpoVR family
GFK26_29975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFK26_29995	COG0625	glutathione transferase activity
GFK26_30010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFK26_30020	COG0346	lactoylglutathione lyase activity
GFK26_30025	COG3070	regulator of competence-specific genes
GFK26_30040	COG0640	Transcriptional regulator
GFK26_30055	COG0431	NADPH-dependent FMN reductase
GFK26_30100	COG1028	Short-chain dehydrogenase reductase Sdr
GFK26_30110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFK26_30175	COG4638	Rieske (2fe-2S)
GFK26_30180	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_30185	COG1414	Transcriptional regulator
GFK26_30205	COG0583	DNA-binding transcription factor activity
GFK26_30210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_30230	COG2267	carboxylic ester hydrolase activity
GFK26_30240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFK26_30250	COG1295	ribonuclease BN
GFK26_30260	COG0277	FAD linked oxidase domain protein
GFK26_30280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFK26_30300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFK26_30305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_30320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_30325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFK26_30330	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GFK26_30335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_30350	COG0535	radical SAM domain protein
GFK26_30360	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GFK26_30365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFK26_30385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_30405	COG3485	protocatechuate 3,4-dioxygenase
GFK26_30445	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_30480	COG2205	protein histidine kinase activity
GFK26_30485	COG1764	response to oxidative stress
GFK26_30490	COG0745	RESPONSE REGULATOR receiver
GFK26_30495	COG0596	Alpha beta hydrolase
GFK26_30500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFK26_30530	COG0243	molybdopterin cofactor binding
GFK26_30530	COG3383	formate dehydrogenase (NAD+) activity
GFK26_30535	COG0437	4 iron, 4 sulfur cluster binding
GFK26_30560	COG0303	'Molybdopterin
GFK26_30575	COG0708	Exodeoxyribonuclease III
GFK26_30590	COG3852	Histidine kinase
GFK26_30605	COG1546	Belongs to the CinA family
GFK26_30605	COG1058	Belongs to the CinA family
GFK26_30630	COG1187	pseudouridine synthase activity
GFK26_30640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_30640	COG4797	methyltransferase
GFK26_30650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GFK26_30710	COG1573	uracil-dna glycosylase
GFK26_30715	COG2323	membrane
GFK26_30720	COG0028	Belongs to the TPP enzyme family
GFK26_30780	COG0517	IMP dehydrogenase activity
GFK26_30795	COG0768	penicillin binding
GFK26_30820	COG2271	Major facilitator Superfamily
GFK26_30825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GFK26_30840	COG0154	amidase activity
GFK26_30870	COG3706	GGDEF domain
GFK26_30870	COG0745	RESPONSE REGULATOR receiver
GFK26_30875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_30900	COG1595	DNA-templated transcription, initiation
GFK26_30915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFK26_30920	COG1595	DNA-templated transcription, initiation
GFK26_30935	COG5001	Diguanylate cyclase
GFK26_30950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFK26_30970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GFK26_30975	COG1605	Chorismate mutase
GFK26_30975	COG0077	Prephenate dehydratase
GFK26_30980	COG0287	Prephenate dehydrogenase
GFK26_30985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GFK26_31005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GFK26_31015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_31030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GFK26_31035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFK26_31035	COG2111	Na H antiporter
GFK26_31040	COG1006	Multisubunit Na H antiporter MnhC subunit
GFK26_31045	COG0651	ATP synthesis coupled electron transport
GFK26_31055	COG2212	antiporter activity
GFK26_31060	COG1320	monovalent cation:proton antiporter activity
GFK26_31070	COG1309	transcriptional regulator
GFK26_31075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_31100	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GFK26_31100	COG3608	succinylglutamate desuccinylase aspartoacylase
GFK26_31170	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_31180	COG2188	Transcriptional regulator
GFK26_31205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_31215	COG1012	belongs to the aldehyde dehydrogenase family
GFK26_31225	COG1802	Transcriptional regulator
GFK26_31230	COG1840	ABC-type Fe3 transport system, periplasmic component
GFK26_31235	COG3842	ATPase activity
GFK26_31265	COG0477	Major facilitator Superfamily
GFK26_31270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFK26_31280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GFK26_31285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GFK26_31290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFK26_31295	COG0142	geranyltranstransferase activity
GFK26_31300	COG1722	exodeoxyribonuclease VII activity
GFK26_31340	COG3064	Membrane
GFK26_31400	COG0747	negative chemotaxis
GFK26_31405	COG0601	transmembrane transport
GFK26_31410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_31415	COG0444	Belongs to the ABC transporter superfamily
GFK26_31420	COG4608	Belongs to the ABC transporter superfamily
GFK26_31425	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GFK26_31435	COG0747	negative chemotaxis
GFK26_31440	COG0601	transmembrane transport
GFK26_31445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_31450	COG4172	Belongs to the ABC transporter superfamily
GFK26_31470	COG0412	Dienelactone hydrolase
GFK26_31495	COG4774	siderophore transport
GFK26_31525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFK26_31535	COG0210	DNA helicase
GFK26_31540	COG3047	cAMP biosynthetic process
GFK26_31545	COG0516	GMP reductase activity
GFK26_31615	COG0583	DNA-binding transcription factor activity
GFK26_31620	COG4948	Mandelate Racemase Muconate Lactonizing
GFK26_31635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GFK26_31645	COG1192	Involved in chromosome partitioning
GFK26_31660	COG0583	DNA-binding transcription factor activity
GFK26_31695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFK26_31700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFK26_31710	COG1253	flavin adenine dinucleotide binding
GFK26_31715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GFK26_31730	COG2197	response regulator
GFK26_31750	COG1116	anion transmembrane transporter activity
GFK26_31755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_31760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_31770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFK26_31780	COG1960	acyl-CoA dehydrogenase activity
GFK26_31785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_31800	COG0513	Belongs to the DEAD box helicase family
GFK26_31805	COG2321	neutral zinc metallopeptidase
GFK26_31810	COG0717	Belongs to the dCTP deaminase family
GFK26_31815	COG0402	S-adenosylhomocysteine deaminase activity
GFK26_31825	COG2366	antibiotic biosynthetic process
GFK26_31830	COG4977	sequence-specific DNA binding
GFK26_31835	COG0583	DNA-binding transcription factor activity
GFK26_31840	COG2814	Major facilitator Superfamily
GFK26_31845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFK26_31850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFK26_31885	COG1129	ABC transporter
GFK26_31890	COG2252	PERMEase
GFK26_31900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFK26_31910	COG0730	response to heat
GFK26_31930	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_31990	COG2351	hydroxyisourate hydrolase activity
GFK26_31995	COG2186	Transcriptional regulator
GFK26_32010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_32030	COG4774	siderophore transport
GFK26_32045	COG1953	Uracil, thiamine, allantoin
GFK26_32060	COG1309	transcriptional regulator
GFK26_32075	COG2233	PERMEase
GFK26_32080	COG0656	L-ascorbic acid biosynthetic process
GFK26_32085	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_32095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFK26_32100	COG0444	Belongs to the ABC transporter superfamily
GFK26_32105	COG4608	Belongs to the ABC transporter superfamily
GFK26_32115	COG0154	amidase activity
GFK26_32160	COG2085	NADP oxidoreductase coenzyme F420-dependent
GFK26_32170	COG0583	DNA-binding transcription factor activity
GFK26_32185	COG1301	dicarboxylic acid transport
GFK26_32195	COG0628	permease
GFK26_32210	COG0583	DNA-binding transcription factor activity
GFK26_32215	COG3960	tartronate-semialdehyde synthase activity
GFK26_32220	COG3622	Belongs to the hyi family
GFK26_32225	COG2084	Dehydrogenase
GFK26_32235	COG0281	malic enzyme
GFK26_32235	COG0280	phosphate acetyltransferase
GFK26_32240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFK26_32255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GFK26_32265	COG1116	anion transmembrane transporter activity
GFK26_32270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFK26_32295	COG0745	RESPONSE REGULATOR receiver
GFK26_32310	COG0642	Histidine kinase
GFK26_32325	COG1733	regulation of RNA biosynthetic process
GFK26_32340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFK26_32350	COG3135	benzoate transporter
GFK26_32365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFK26_32370	COG0590	tRNA wobble adenosine to inosine editing
GFK26_32375	COG0829	nickel cation binding
GFK26_32395	COG2855	membrane
GFK26_32405	COG2879	small protein
GFK26_32410	COG1966	Carbon starvation protein
GFK26_32465	COG0791	NLP P60 protein
GFK26_32505	COG0667	Aldo Keto reductase
GFK26_32510	COG2814	Major facilitator Superfamily
GFK26_32535	COG0559	Belongs to the binding-protein-dependent transport system permease family
GFK26_32575	COG0613	PHP domain protein
GFK26_32585	COG0009	L-threonylcarbamoyladenylate synthase
GFK26_32590	COG1994	Peptidase M50
GFK26_32595	COG0180	Tryptophanyl-tRNA synthetase
GFK26_32600	COG2197	response regulator
GFK26_32605	COG2205	protein histidine kinase activity
GFK26_32605	COG2198	Histidine kinase
GFK26_32605	COG0784	Response regulator, receiver
GFK26_32610	COG1950	PFAM Membrane protein of
GFK26_32620	COG0583	DNA-binding transcription factor activity
GFK26_32625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFK26_32630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFK26_32635	COG1538	Outer membrane efflux protein
GFK26_32665	COG3501	Rhs element vgr protein
GFK26_32700	COG1191	sigma factor activity
GFK26_32715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFK26_32725	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GFK26_32730	COG0745	RESPONSE REGULATOR receiver
GFK26_32745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFK26_32750	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GFK26_32755	COG2198	Histidine kinase
GFK26_32755	COG0643	Histidine kinase
GFK26_32780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFK26_32800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GFK26_32805	COG1334	flagellar protein FlaG
GFK26_32825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFK26_32850	COG1580	Controls the rotational direction of flagella during chemotaxis
GFK26_32860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFK26_32865	COG3190	flagellar
GFK26_32875	COG1987	bacterial-type flagellum assembly
GFK26_32895	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GFK26_32945	COG1256	bacterial-type flagellum assembly
GFK26_32955	COG0835	chemotaxis
GFK26_32960	COG0840	transmembrane signaling receptor activity
GFK26_32980	COG0840	transmembrane signaling receptor activity
GFK26_32985	COG1705	Flagellar rod assembly protein muramidase FlgJ
GFK26_32985	COG3951	Flagellar rod assembly protein muramidase FlgJ
GFK26_33000	COG4786	Flagellar basal body rod
GFK26_33010	COG1749	Flagellar hook protein flgE
GFK26_33015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GFK26_33020	COG1558	bacterial-type flagellum-dependent cell motility
GFK26_33025	COG1815	bacterial-type flagellum-dependent cell motility
GFK26_33055	COG0583	DNA-binding transcription factor activity
GFK26_33065	COG0583	DNA-binding transcription factor activity
GFK26_33075	COG3181	Tripartite tricarboxylate transporter family receptor
GFK26_33085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GFK26_33095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GFK26_33100	COG1047	Peptidyl-prolyl cis-trans
GFK26_33105	COG2003	Belongs to the UPF0758 family
GFK26_33115	COG0737	Belongs to the 5'-nucleotidase family
GFK26_33130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GFK26_33140	COG0765	amino acid transport
GFK26_33145	COG0765	amino acid transport
GFK26_33160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFK26_33165	COG0477	Major facilitator Superfamily
GFK26_33170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GFK26_33175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFK26_33180	COG1845	cytochrome c oxidase, subunit III
GFK26_33185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GFK26_33200	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GFK26_33205	COG1272	protein, Hemolysin III
GFK26_33215	COG0477	Major facilitator Superfamily
GFK26_33220	COG0583	DNA-binding transcription factor activity
GFK26_33235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GFK26_33240	COG0709	Synthesizes selenophosphate from selenide and ATP
GFK26_33245	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GFK26_33250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_33255	COG3639	organic phosphonate transmembrane transporter activity
GFK26_33265	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GFK26_33270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFK26_33280	COG0243	molybdopterin cofactor binding
GFK26_33290	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFK26_33295	COG4149	molybdate abc transporter
GFK26_33305	COG0583	DNA-binding transcription factor activity
GFK26_33310	COG0489	protein tyrosine kinase activity
GFK26_33320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFK26_33325	COG1473	amidohydrolase
GFK26_33330	COG1522	sequence-specific DNA binding
GFK26_33335	COG3132	Protein of unknown function, DUF480
GFK26_33345	COG0473	3-isopropylmalate dehydrogenase activity
GFK26_33350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_33350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFK26_33370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFK26_33380	COG1024	Enoyl-CoA hydratase
GFK26_33380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFK26_33385	COG0659	secondary active sulfate transmembrane transporter activity
GFK26_33405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GFK26_33410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GFK26_33415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GFK26_33420	COG0602	queuosine metabolic process
GFK26_33425	COG0720	synthase
GFK26_33430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GFK26_33440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GFK26_33445	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GFK26_33455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFK26_33460	COG0588	phosphoglycerate mutase activity
GFK26_33465	COG0793	Belongs to the peptidase S41A family
GFK26_33470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFK26_33475	COG2982	Protein involved in outer membrane biogenesis
GFK26_33485	COG2197	response regulator
GFK26_33495	COG5487	UPF0391 membrane protein
GFK26_33515	COG2823	Periplasmic or secreted lipoprotein
GFK26_33545	COG0494	nUDIX hydrolase
GFK26_33560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GFK26_33580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GFK26_33595	COG2226	methyltransferase
GFK26_33620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFK26_33630	COG1175	transmembrane transport
GFK26_33635	COG0395	ABC-type sugar transport system, permease component
GFK26_33640	COG3842	ATPase activity
GFK26_33645	COG0584	glycerophosphoryl diester phosphodiesterase
GFK26_33650	COG3264	Mechanosensitive ion channel
GFK26_33650	COG1511	domain protein
GFK26_33655	COG1522	sequence-specific DNA binding
GFK26_33665	COG4120	Belongs to the binding-protein-dependent transport system permease family
GFK26_33670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFK26_33685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GFK26_33690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GFK26_33695	COG2890	protein-(glutamine-N5) methyltransferase activity
GFK26_33700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GFK26_33705	COG1253	flavin adenine dinucleotide binding
GFK26_33710	COG0741	lytic transglycosylase activity
GFK26_33715	COG0442	prolyl-tRNA aminoacylation
GFK26_33720	COG0494	nUDIX hydrolase
GFK26_33730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GFK26_33735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GFK26_33740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GFK26_33745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GFK26_33750	COG0142	geranyltranstransferase activity
GFK26_33770	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GFK26_33790	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GFK26_33795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GFK26_33810	COG0494	nUDIX hydrolase
GFK26_33820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFK26_33825	COG0653	protein targeting
GFK26_33855	COG0831	urea catabolic process
GFK26_33870	COG0804	urea catabolic process
GFK26_33905	COG0583	DNA-binding transcription factor activity
GFK26_33915	COG0583	DNA-binding transcription factor activity
GFK26_33935	COG1028	Short-chain dehydrogenase reductase Sdr